BIOBASE Discrete Automatic Biochemical Analyzer Operation
Contents
1. Reagent volume R1 25 300ul R2 10 150ul 1ul per step Reagents the minimum reaction solution is 180ul Address No 51 South Gongye Road Jinan Shandong China 250101 8 BIOBASE TEL 0531 82373183 FAX 0531 81219880 Emergency samples place the emergency samples and control materials to any location in the sample dial at any time automatic detection is given priority Calibration one point calibration multi point calibration QC quality control can be joined at any time The same item can have up to six kinds of quality control Reaction time about 15 minutes Optical system Interference Filter nm 340 405 450 510 546 578 630 700 Detection of single and dual wavelength Light source 12V 20W halogen lamps optical fiber guides light Accept 8 imported photoelectric receiver The linear range 0 000 2 500 Abs Temperature Control 1 the temperature of reaction disk is 37 0 1 C 2 the reagent is refrigerated at the temoerature which is 8 C lower than that of the room Reaction cup 120 micro violet plexiglass material cuvette standard optical path is 6mm in length The liquid level detection automatic level sensing probes Software English interface of Windows 2000 or more superior version Power supply AC220V 22V 50Hz 1Hz 1 5KW 3 8 Installation Requirements 3 8 1 Installation Environment 1 indoor installation only 2 the ground should be flat inclination should be less than 1 2002. The query has two sub menu Query of quality control results and the test results 8 1 1 Query for Test Results In the data processing interface click the Data management Test Results Query menu click the Query menu then click Results query the following interface appear Routine Operation S Parameter T Specific Test P Service And X User Y Help H Exit E gt R H lt 3 EB 28 Reaction Curve L Data Maintenance M xW Results Query TE S ey Informatiorg _o Serum f vlBeano E L E op Address No 51 South Gongye Road Jinan Shandong China 250101 37 BIOBASE TEL 0531 82373183 FAX 0531 81219880 Queries can be carried out by a variety of ways such as the date name patient number registration number there are three kinds of query date name and sample number If according to the name select the correct date confirm the registration number of the day to display in the sample number column select the appropriate number of samples the results are displayed in the results column click the button Print then print a report Also can use a combination of query enter a few queries such as at the same time to enter the date and name 8 1 2 Query for QC Results In the data processing interface click data management click the Query QC Query appears appear the following interface e Operation S Parameter T Specific Tes
3. 3 BIOBASE Sapphire ground is able to withstand 100kg of weight at least 4 there should be no direct sunlight in venues 5 there is less dust less vibration and low noise in venues 6 should not be close to strong electrical interference sources 7 a good grounding and grounding resistance is less than 40 3 8 2Temperature and Humidity 1 room temperature should be between 15 30 C 2 the relative humidity shoud be no higher than 80 3 the room should be well ventilated Address No 51 South Gongye Road Jinan Shandong China 250101 9 BIOBASE TEL 0531 82373183 FAX 0531 81219880 3 8 3 Installation Space 90cm 100cm 60cm Figure 4 Installation space schematic Main unit BIOBASE Sapphire length 90mm x width 740mm x height 60mm INote power supply board at the rear of the side of the instrument should not be blocked off which is to facilitate the operation of the power switch 3 8 4 Power and Grounding 1 power supply AC 220V 22V 50Hz 1Hz 2 Input power BIOBASE Sapphire 400W 3 grounding resistance lt 4Q 3 8 5 Deionized Water Less than 5 liters per hour conductivity is less than 2 0us cm 3 9 Transport and Storage Requirements In the packaging state analyzer should be transported according to the ordering contract Severe impact rain and exposure should be avoided during transport Packaging analyzer should be stored at 0 C to 40 C with relative humidity no more than 85 non
4. Blank Category reagent blank and sample blank value If you choosee reagent blank you can get the final absorbance test value by deducting in the test the he reagent blank of total absorbance If you choose sample blank firstly test sample blank in each sample test and then test the reactant absorbance the absorbance of the reactants minus sample blank absorbance will get the final absorbance data Standard number multiple standards each standard should has its unique number Standard batch number input batch number of standard material Absorbance values when calibration the instrument measures absorbance values of standard material Calibration factors the instrument calculate the coefficients according to the concentration of standard material the absorbance value reagent blank and calibration formula Address No 51 South Gongye Road Jinan Shandong China 250101 31 BIOBASE TEL 0531 82373183 FAX 0531 81219880 Concentration input the concentration of standard material Cup No when calibrating standard material should be placed on the location of the sample circle The graphic box showd the calibration curve after calibration the horizontal axis is the absorbance OD value and the vertical axis is the concentration value Change the scale of the abscissa scale you can change the horizontal aspect ratio Change the scale of the ordinate scale can change the horizontal aspect ratio The current calibration selec
5. following interface appear Routine Operation S Parameter T Specific Test P Data Management M Service And Adjust X User Y Help H Exit E S smu EB OW ee Vy A sU Report Add input item oaee LPT Mem MSO Select the number of samples in Sample ID list box and the results are displayed in the results column If you need patient information please enter patient information in patient information column If you need to print other test results some other relevant information can be input to the adding column The results can also be edited in the interface After the test result is confirmed please select to print the current report or the whole report or choose to print a range of the report After finishing the detection please turn off the system exit the test interface and turn off your computer 5 Routine Operation 5 1 Flow Chart Turn on the machine Warm up for 30 minutes Address No 51 South Gongye Road Jinan Shandong China 250101 17 BIOBASE TEL 0531 82373183 FAX 0531 81219880 YES oe specimen information entering Detect specimen Finish the detection Turn off the machine Figure 8 daily operation flow chart 5 2 Specimen Detection 5 2 1 Preparation for Detection 1 specimen preparation Serum samples will be available after centrifuging the tested blood The serum should not have clot hemolysis and other pheno
6. 40G Monitor should be 15 inches or more in length and resolution shoud be no less than 1024 x 768 The printer should be a ordinary inkjet or laser printer The main structure of the biochemical analyzer s main unit Sample parts the reagent dial sample dial sample arm the reagent arm diluting instrument Detection parts optical system filters signal acquisition 3 5 The Scopes of the Products This product is suitable for medical and biochemical analysis test 3 6 Sample Collection The sample must be fresh specimens collected in the same day Serum is centrifuged samples from the sample as test specimens and sample should not have the phenomenon of hemolysis or coagulation INote The specimens may carry infectious bacteria Dood protection is needed when handling specimens Operator should wear a mask and put on work clothes to avoid being infected and in some cases protective glasses is a necessity When handling waste operator should wear a mask and put on work clothes to prevent infection and in some cases protective glasses is a necessity Please observe the local emission standards and consult the reagent manufacturer or distributor 3 7 Technical Data Sheet Analysis Method End point method two point method dynamic method turbidimetric method Analyzing item Maximum of analyzing 45 items at the same time Programming items program any test items Sample volume 2 uL of 50ul of 0 1ul per step
7. If you do not set dual wavelength select blanK of the second wavelength Test method the end point method the two point method dynamic method turbidimetry select according to the test reagents and methods typical reaction curves are as follows Address No 51 South Gongye Road Jinan Shandong China 250101 25 BIOBASE TEL 0531 82373183 FAX 0531 81219880 Figure 10 Endpoint method response curve diagram Figure 11 dynamic method reaction curve diagram Slope If the absorbance readings are becoming bigger that is a positive slope If the absorbance readings are becoming smaller that is a negative lope Maximum slope it represents the maximum allowable amount of absorbance change If it is larger than the set value indicating that there is error the sample which is being analyzed Instrument gives failure code suggesting that the specimen need to be retested Reading point the main reading segment is beginning time of reading and the period of reading time There are 40 points of the instrument in the whole process of reading interval of each point is about 18 seconds and the entire reading time is 40 x 18 720 seconds 12 minutes If you choose the third minutes as the starting point the reading interval is three minutes Then the starting value is 10 the end value is 20 If you need to adopt the blank sample method during the test you should read blank sample while reading You should apply the method of Sec re
8. heating power and temperature control circuit and regulator power supply of 12V 20W light etc reagent disk control circuit stepper motor controls drive reagent position sensor and provides two cooler power that ensures reagent refrigeration and temperature control circuit etc syringe control circuit is driven by two stepper motors which respectively drive the sample syringe and reagent syringes two position sensors sense the original location of the syringe and a solenoid valve controls cleaning and conversion of the sample sample disk control circuit consists of a stepper motor and a position sensor The position sensor is a photoelectric sensor The interface circuit consists of two 8051 single chip microcomputers and some peripheral circuits and is used to the convert the command sent by the computer into executable command for various moving parts so as to coordinate the work of the various components meanwhile it sends the A D conversed digital signal and instrument status information to the computer Address No 51 South Gongye Road Jinan Shandong China 250101 5 BIOBASE TEL 0531 82373183 FAX 0531 81219880 3 3 Software User Interface special test parameter data processing maintenance routine test calibrated quality parameters of query of routine repeated test control tests test tested item patient s maintenance Test print the of reagent parameters of result calibrate the result Figure 3 Software stru
9. light cover 5 Set the rear cover Note in order to do this power must be disconnected to avoid electrical shock and you have to wait until the old light source lamp cools completely before replacing it with a new one so as to avoid burns 9 5 2 Syringe Replacement Syringe may be leaking after working for a period of time six months or so then it must be replaced 1 Remove the rear cover 2 Replace the syringe piston which is leaking and note that screws should be set firmly 3 Set the rear cover 9 5 3 Reagent Sample needle Replacement If damaging a needle accidentally you must replace it with a new one need Address No 51 South Gongye Road Jinan Shandong China 250101 44 BIOBASE TEL 0531 82373183 FAX 0531 81219880 professionals do the replacement and adjustment work 1 Carefully remove the top cover of the needle 2 Remove the screws 3 Change a new needle 4 Fix the needle 5 Adjust the position of the needle through using the procedures software of needle adjustment 6 Cover the top cover INote that the postion of the needle must be aligned otherwise it will damage the new needle 10 Malfunction Analysis 10 1 No Respond after Startup Check the power plug and the instrument fuse INote Please use the fuse with a specification of 5 x 20 Please replace the fuse according to the specification markd on the instrument 10 2 Light Source Can not be Lit Check whe
10. reliable analytical instruments Second reagents of stable performance Both are Indispensable In the basis of ensuring high quality instrument performance we suggest that users should buy product of trustworthy quality for the accuracy of your test results Firstly it is the reagent are approved by the state Secondly it is the products are verified by the majority of users 11 Warranty Commitment 1 Warranty period lasts twelve months from the date of purchase 2 During the warranty period if the instrument is damaged which is due to improper use or any accident the Company will not assume any responsibility or obligations 3 After the warranty period the company is also Address No 51 South Gongye Road Jinan Shandong China 250101 47 BIOBASE TEL 0531 82373183 FAX 0531 81219880 responsible for maintenance but it will charge maintenance fee Please provide maintenance organizations or maintenance personnels trained and approved by the company with drawings of the instrument and part of the necessary technical data 4 Please contact the service department of the company to purchase the spare parts Not the Spare parts of our company are likely to cause damage to the instrument and affect the use of the instrument Note Cuvette sample cup reagent bottle halogen lamp syringe sample reagent needle fuse are all consumables and not included in the warranty Manufacturer Jinan Biobase Biotech Co Ltd Addr
11. BIL OXI 13 TP 14 ALB 15 CREA ALK 16 CREA ALK 17 UREA 18 UREA 19 UA 20 UA 1 25 5496 5 5878 25 5496 5 421 11 9544 4 4619 0 0 0 0 0 0 22 7368 24 3776 9 376 10 0792 9 962 3 1275 9 6104 2 919 Modify 1 2 1 2 1 2 1 2 1 2 1 2 1 1 1 2 1 2 1 2 In this interface you can enter the information of the reagent Position reagent box is placed on corresponding location of number in the reagent disk range No 1 No 56 Items are selected in the drop down list of the input box Bottle type maximum volumn of reagent box ml The height of the reagent box net height of the reagent box mm Reagent type place of the first reagent or the second reagentR1 or R2 Choose a position number Click it Then under the position list input the information in blanks follow the Number position Item name Bottle type reagent type Address No 51 South Gongye Road Jinan Shandong China 250101 35 BIOBASE TEL 0531 82373183 FAX 0531 81219880 If you test the remaining reagent volume click the Test button the instrument automatically detects the reagent stock and calculate the number of items that can be tested INOTE The reagents location can not be misplaced before the test reagent please make sure there is sufficient reagent for testing items 7 5 Instrument Performace Test For the needs of Instrument performance test and the calculation we should test absorbance of some standar
12. BIOBASE TEL 0531 82373183 FAX 0531 81219880 BIOBASE Discrete Automatic Biochemical Analyzer Operation Manual Please read this operation manual before using the analyzer Keep the manual for accessing information Executive Standard of the Product YZB Lu 0146 2011 Registration Number Lu Food and Drug Administration Word 2011 No 2400179 BIOBASE Jinan Biobase Biotech Co Ltd BIOBASE TEL 0531 82373183 FAX 0531 81219880 1 Warning label description Warning biohazard Warning be careful of electric shock gt pe Note be careful of the danger it could cause personal injury or equipment damage gt Warning Be careful of burns 2 Overview Automatic Biochemical Analyzer BIOBASE Sapphire is the hospital s routine in vitro diagnostic equipment and it is an instrument used in testing a variety of biochemical index in the body fluids of patients It is necessary to read this chapter carefully before using BIOBASE Sapphire This chapter includes important information about using the BIOBASE Sapphire and some imprtant information of this user manual Please use the device in accordance with the provisions of this manual so as to avoid potential personal injury or equipment damage 2 1 About This Manual This manual can help the user use BIOBASE Sapphire in a safe and correct way For this purpose the manual will introduce the BIOBASE Sapphire components and working principle This manual intro
13. Optical System 1 light source 2 fiber guided beam 3 Cuvette 4 interference filter 5 Optoelectronic receivers Figure 1 the optical path diagram Instrument optical system shown in Figure 1 Light of light source shoots upon the fiber end and then is divided into eight beams which act as the incident light shooting upon the cuvette The beams become monochromatic light after shooting through the solution and go into interference filter soectrophotometric and then shoots a photoelectric receiver We choose the quartz glass halogen lamp of 12V 20W as thr light source ant the light source collimates into a parallel beam of 2 5mm diameter We should use rectangular discrete plexiglass cuvette of 6mm optical diameter through which UV can shoot through cuvettes Cuvettes should be uniform in the shape and there should be no scratches on the surface of light transmission hole Light transmittance slot of precise 120 attainment yards disk align at the middle of the cuvette so as to ensure the readings sampling point is in the middle of the cuvette 120 cuvettes are placed in a circle of the reaction plate with the smallest volume of 180ul The advantage is that there is no cross contamination Taking into account the speed of rotating colorimetric turntable we use static eight way splitter system and integrated components package consisting of import filters and optical receiver to test wavelength of 340 405 450 510 546 578 630 700 with spectral ha
14. adings meaning reading the blank sample data in the auxiliary reading section read the response data in the main reading section and process data according to the need Auxiliary reading section is located before main reading section Please set the data according to the need Second reagent Figure 12 Auxiliary reading segment diagram Normal range it refers to the normal range of the test results the instrument will prompt in the test results when surpassing this normal range Address No 51 South Gongye Road Jinan Shandong China 250101 26 BIOBASE TEL 0531 82373183 FAX 0531 81219880 Linear correlation If the machine s test results are different from expectations you can be modify the result according to the formula Y AX B change the coefficient A and B to amend the test results Unit Concentration units can be selected in the drop down list Accuracy the number of decimal places of the test results can be selected in the drop down list Maximum rate of change A min It refers to the maximum absorbance change In particular when controlling enzymatic measurement due to the high concentration reaction is violent change of absorbance is rapid so substrate is depleted and false results if this happens the instrument will prompt re test the specimen If you want to modify the item parameters select the item in the list of items column click Edit button and then the cursor can be moved to necessary
15. an be scrolled to show all the test data 5 3 Testing the Emergency Specimens In the process of testing specimens emergency specimens can be inserted at any time Put the specimens on the sample ring specimens can be placed on any vacancy in the sample circle Action should be quick do not place the specimens while the sample circle is rotating Sample order menu interface is as follows Emergency interface and routine test interface is roughly the same and the difference is that when entering the emergency sample one should select the emergency check box see above The other input is the same with a L Erone common sample After the input is completed and the current sample is finished the instrument will test emergency specimens 5 4 Re testing Sample Inputting If the item of some specimens was found too high in concentration or other bad results you can re test it The test results will overwrite the original data We can enter the Repeat test and the interface is as follows Routine Operation S Parameter T Specific Test P Data Management M Service And Adjust X User Y Help H Exit E S slm tho EB OY be Ty gt A t Repeat Order Marlee Irirorrsicitle rl Address No 51 South Gongye Road Jinan Shandong China 250101 22 BIOBASE TEL 0531 82373183 FAX 0531 81219880 As follows Select the number of specimen which will be retested edit it Select the items whic
16. corrosive gases and a well ventilated environment 3 10 Standard Configuration Unit There is no Name corresponding Quantity Remarks units of quantity in English Serial number Address No 51 South Gongye Road Jinan Shandong China 250101 10 BIOBASE TEL 0531 82373183 FAX 0531 81219880 l Main unit l l 2 Manual I 1 Warranty card l jl 4 Certificate l 1 5 Accessories box 5 1 AMRS I 1 Quantity 500 5 2 Cuvette I 9 Positioning block of 5 3 reagent bottle I 45 5 4 Bucket l 9 RS232 5 9 communication cable 1 5 6 Power cord l 1 57 Operating software l 1 CD CD ROM 5 9 EASMARIRES I 1 4mm X 6mm 5 9 ESEMANBNES I 1 6 5mmX 10mm 5 10 Simple tools l 1 5 11 Spare halogen light l i 5 12 e 2 5 13 Water falling head l 9 5 14 Yellow green ground 2 Large joints and nuts 5 15 of large joints l 1 Small joints and nuts 5 16 of small joints l 3 Address No 51 South Gongye Road Jinan Shandong China 250101 BIOBASE TEL 0531 82373183 FAX 0531 81219880 4 Overview of System Operation 4 1 Introduction of the System 4 1 1 Hardware 1 the main unit BIOBASE Sapphire automatic biochemical analyzer is a landing automatic biochemical analyzer which adopts stand cuvette The instrument is operated without human intervention during the whole processo and the reagent dial has the functio
17. cture diagram The software consists of two parts namely computer operating software and single chip control software the framework of computer operating software is shown in Figure 3 The user interface is formed by Visual Basic development tools in Windows2000 platform and its database is in Access forms Under the unified user interface specific function is accomplished by each sub module Routine testing menu is mainly to complete the daily work and it consists of several sub menus the conventional test is carried out in entry of the day to day specimens information of the patients in the choice of test items and in testing samples and it is the most commonly used software module of the instrument emergency test is carried out in emergency specimens entry and in emergency insertion test of emergency specimens priority having been given to some choreographed specimens real time results show that real time display of test results for each specimen response curve display module can display the reaction curve of a sample in any testitem and at any time so as to easily understand the details of the test instrument status submenu can show real time display of each work status of the instrument Printing the result means to verify the detected samples results print test results reports and give it back to patients Thus a complete cycle is completed The parameter setting menu is to complete the module produced by various parameters and i
18. d solution Enter this program module absorbance test and Instruments stability can be carried out In the main interface click the Reading absorbance under specific test menu to enter the above interface xt Reading Absorbance Stability Test Reading Abs Click Stability test Select the time interval for reading Maximum one hour After the data is entered correctly click the button start into test process After the start of the test every 12 seconds to refresh the data every five minutes to a records until the set time interval Observation data changes and determine the stability of the instrument Address No 51 South Gongye Road Jinan Shandong China 250101 36 BIOBASE TEL 0531 82373183 FAX 0531 81219880 Click Reading abs Select the desired wavelength in wavelength drop down list after sample in cuvette is ready click the button start and the instrument begins reading After the reading is completed the table shows the numbe of the cuvette and corresponding absorbance values select the number of the cuvette to find the corresponding measured absorbance value Note In the process of the instrument performance tests must be at 120 cuvette deionized water was added as a water blank 8 Data Processing The data processing consists of three sub menu test results query response curves and data maintenance for data query processing 8 1 Search for Test Results
19. dle position 9 4 Instrument Maintenance 9 4 1 Daily Maintenance 1 clean bucket empty waste water bucket 2 check the position of pipetting needle and the position of and whether there is blockage in the head of reagent needle and samples needle 3 check whether there is blockage in cleaning mouth 9 4 2 Weekly Maintenance 1 Use cleaning fluid to clean the pipetting needle reagent needle and stirring needle 2 Clean the surface of the instrument 3 Clean positions holding reagent 9 4 3 Maintenance for Every 6 Months 1 check whether the light source lamp is normal replace it if necessary 2 check whether the injection pump is working properly 3 check whether the syringe leaks and replace it if necessary with a new syringe 9 4 4 Annual Maintenace 1 Check whether the power supply voltage and the ground wire is in good contact 2 Maintenance robotics arm 3 Water pipe replacement Address No 51 South Gongye Road Jinan Shandong China 250101 43 BIOBASE TEL 0531 82373183 FAX 0531 81219880 4 Adjustment of the instrument position 9 5 Spare Parts Replacement 9 5 1 Light Source Lamp Replacement It is generally required to replace the light source lamp within six months or after 1500 hours of work time 1 Open the rear cover 2 Remove the light cover 3 Remove the old light source lamp and replace it with a new light source lamp 12V 20W Note that the connector must be firm 4 Set the
20. duces in a detailed way the necessary software and hardware knowledge for operating the BIOBASE Sapphire After having some knowledge of the components of BIOBASE Sapphire we will teach you step by step how to use these modules to complete routine tasks After reading this munual thoroughly believe you can operate BIOBASE Sapphire well We will use some warnings hints and very useful comments emphasizing the key chapters which have a striking Note mark Address No 51 South Gongye Road Jinan Shandong China 250101 1 BIOBASE TEL 0531 82373183 FAX 0531 81219880 This manual applies to BIOBASE Sapphire 2 2Introduction The Biosafety automatic biochemical analyzer is optional automatic biochemical analyzers Jinan Xin Biobase Biotech Co Ltd These types of analyzers use 120 discrete cuvettes with a moderate analysis speed no cross contamination and few consumables their reagents are opening and other advantages Thank you for choosing our products We will always provide services for you If you have any requirments please notify us We will do our utmost for you Automatic biochemical analyzer is a conventional hospital diagnostic equipment and it is an instrument used in testing a variety of biochemical index in the body fluids of patients Since 1960s when the first biochemical analyzer was made it has been developing by leaps and bounds Whether from the instrument s accuracy or manufacture of precision as well as i
21. e passwords Please keep in mind the modified password When entering a new test item or replace reagents you need to change test parameters Parameter setting process is as follows Click the Paremeter menu of Item parameters in the main interface input the password 00000000 and enter the following Address No 51 South Gongye Road Jinan Shandong China 250101 24 BIOBASE TEL 0531 82373183 FAX 0531 81219880 Routine Operation S Parameter T Specific Test P Data Management M Service And Adjust x User Y Help H Exit E slesan mA ha e r Al Parameter 40 00 High 150 0 Click the item name in the item column such as ALT the background of the item turns blue At this point item number item name full name the test item parameters and other information of the tested item are revealed Sample parameters sample volume the volume of the first reagent the volume of the second reagent These data will limit the volume of solution extracted by sample syringe reagent syringe input range of sample is between 2 50ul the volume of the first reagent 25 300ul the volume of the second reagent 10 150ul If you do not set the second reagent you can enter 0 or not input anything in the second reagent bar The test parameters are as follows Test the dominant wavelength select among 340 405 450 510 546 578 630 700 Test the Auxiliary wavelength select among 0 340 405 450 510 546 578 630 700
22. e position of cuvette We can adjust the horizontal position of the sample arm through Step and Step button save the changes through the OK button Cancel button to abandon changes 9 3 2 Vertical Adjustment of Sample Arm Adjusting the maximum depth of the pipetting needle vertically This adjustment corresponds the reagent arm gt gt the vertical adjustment Click related Ei Through adjusting cleaning position reagent position the reaction cup position and sample position adjusting with the help of Add a step and Reduce a step button to make pipetting needle reach the maximum depth If the pipetting needle can not touch reagents or samples in this depth the instrument can not test the specimen OK button to save the adjustment and Cancel button to abandon the adjustment Address No 51 South Gongye Road Jinan Shandong China 250101 42 BIOBASE TEL 0531 82373183 FAX 0531 81219880 Pipetting needle is better to be adjusted to the bottom position of the sample cup I Note SampLe cup and test tube could select one only during adjustment Stirring pin reagent arm and cleaning needle adjustment is similar to that of sample arm 9 3 3 Adjustment of Sample Tray and Reagent Tray Horizontal position of sample Tray reagent dial should be in the middle position of the pipetting needle if there is any variant just modify the data then could adjust the position until adjust to the mid
23. ems contain computational item and manual item otherwise the item data will not be to print 2 The project has been deleted in item parameters setting It should be deleted here otherwise it will go wrong 9 Maintenance 9 1 Instrument Initialization Click Initialization of Service and adjust menu the instrument reset can be reset 9 2 Instrument Check If instrument failure appears you can use the instrument software to test the Address No 51 South Gongye Road Jinan Shandong China 250101 40 BIOBASE TEL 0531 82373183 FAX 0531 81219880 various components in order to find the cause of the malfunction click Parts Testing the software interface is as follows 9 2 1 Syringe Test There are reagent syringe and sample syringe There is a text box after each syringe enter the syringe capacity and click the Execute button in the text box syringe will move to the shape of desired capacity click the orginal button syringe moves upward to the original location If syringe does not move or not move to the disired shape there is a fault of the syringe 9 2 2 Sample and Reagent Arm Test Mechanical movement test of sample arm is done by x button It can move to the level zero reagent place sample place the reaction cup place We can detect the vertical position of the sample arm the test of cleaning arm and mixing arm is the same of that of sample arm 9 2 3 Turntable Test The instru
24. er multiple quality control specimens Use Edit and delete button to modify the input data entry information can be shown in the QC entry list If the data is entered correctly withdraw from the interface and then open the Sample order page click add choose the QC and Lot then choose the related test items click ok then open testing page start the test In the test process you can click the stop test button to stop the test The test results are shown in real time in the results column and the results are stored in the QC database 7 4 Reagents The instrument has a reagent disk in which 56 reagent boxes can be placed order of reagents shall be set in the reagent status interface The interface can estimate how many tests can the remaining reagents in the reagent boxes can do so as to avoid the situation that reagent is in shortage in the test process On the main interface click the reagent status menu under the specific test menu to appear the following interface Routine Operation S Parameter T Data Management M Service And Adjust X User Y Help H Exit E gt slealt Soe leee l CE Washing and Blank W Reading Absorban H Address No 51 South Gongye Road Jinan Shandong China 250101 34 BIOBASE TEL 0531 82373183 FAX 0531 81219880 a Reagent Status Hon 1 ALT 2 ALT 3 AST 4 AST 5 ALP 6 ALP 7 GGT 8 GGT 9 TBIL OXI 10 TBIL OXI 11 DBIL OXI 12 D
25. ess No 51 South Gongye Road jinan China Tel 86 531 82373183 Fax 86 531 81219880 Address No 51 South Gongye Road Jinan Shandong China 250101 48
26. ge the second method is to enter the quality control test interface to do quality control test Select the quality control mode in Test Mode Routine Operation Specific Test P Data Management M Service And Adjust X User Y Help H Exit E D a Hale l Specific Parameters S Calibration Parameters C QC Parameters Q Normal Value Range N Please firstly set the quality control parameters before doing quality control click QC Parameters button to display the interface below Click the add button OC Parameter Address No 51 South Gongye Road Jinan Shandong China 250101 33 BIOBASE TEL 0531 82373183 FAX 0531 81219880 Click add input the batch numberof QC QC lot NO Select test items in optional item column to add it to the QC items column steps are the same as describe above In the QC items column click an item and enter the average value standard deviation and range of the item repeat the above steps you can enter quality control data for each item Press the Edit button to edit the input values Click the OK button to save the data In Quality control colunm press add button to enter Registry Number placing number of quality control indicating the quality control specimens were placed in the placing number of sample ring and batch number of quality control In t items column select an item and add it to QC items column Repeat the above steps and ent
27. h will be retested and add them to the selected item Repeat the above process multiple input samples Click Save to enter the test interface for test 5 5 Registration and Print of the Results Routine Operation Parameter T s Jat to enter the following interface Click Report or Routine Operation S Parameter T Specific Test P Data Management M Service And Adjust X User Y Help H Exit E S 3 0 ta EE P Ya e Vy gt lO A Report x 2 g Output as fo s s Calculate Delete Sample i Nelefe Item D The specimen test results of the day can all be found in the results sample box First select the number of samples and test results are displayed in the results column If it is needed to enter patient information please enter the patient information in patient information column If need to print other test results in the report you can also add item name in addition column and enter data in the results column If you want to edit the test results move the cursor to results column in which the results are needed to be replaced Enter the new results and confirm If all the samples have not been tested and you want to print part of the results report release the report while testing the sample you have to click the button of Calculate the item Once the specimen is tested the calculation results will appear immediately otherw
28. he user should first turn off the power of the BIOBASE Sapphire and disconnect the powe 2 7 Computer Preventive Measures Some measures should be taken to guard against computer viruses and the computer can not be used for other purposes The computer should only use the user software written for BIOBASE Sapphire by Jinan Biobase Biotech Co Ltd 2 8 Processing Machines Please dispose of the analyzer in accordance with local waste disposal standards 3 Introduction 3 1 Basic Principles According to the Lambert Beer law when a bunch of incident light shoots through the colorimetric solution there is the law concerning the incident light transmitted light and the solution of light absorption A LogioT KCL T I lo lo Incident light intensity Transmitted light intensity A Absorbance C Concentration L Optical path k Coefficient The testing principle of biochemical analyzer mainly applies light absorption the Lambert Beer law by measuring the absorbance of the monochromatic light which shoots through the liquid mixture of the serum or urine and other body fluids and reagents to determine whether human physiological indicators are normal 3 2 Hardware In order to auto complete specimen test hardware support is indispensable Address No 51 South Gongye Road Jinan Shandong China 250101 3 BIOBASE TEL 0531 82373183 FAX 0531 81219880 which includes the following aspects 3 2 1
29. ial user name and password are number 1000 if they are confirmed yon can go to the BIOBASE Sapphire main test interface Address No 51 South Gongye Road Jinan Shandong China 250101 14 BIOBASE TEL 0531 82373183 FAX 0531 81219880 Please be ready to detect the specimens after the main unit has warmed up for 30 minutes Please be ready to detect the specimens after the main unit has warmed up for 30 minutes 4 2 3 Test the Sample Specimens The software interface is as follows Routine Operation S Parameter T Specific Test P Data Management M Service And Adjust X User Y Help H Exit OBA er pee tl Click on the Routine operation to enter the following interface FRR emeen specricrest Dota Managemeni M Senice And AISO User Hep KE eera EAE 94 aa lS AO A Repeat Test R Testing T Report P Click on the sample order into the following interface Routine Operation S Parameter T Specific Test P Data Management M Service And Adjust X User Y Help H Exit E oo 3 C0 e Vy 29 _ t Sample Order Haitians lifer Le a ell a a Ld r a 4 2 4 Enter the Patient Information and Test Items Click add button to enter the patient information Address No 51 South Gongye Road Jinan Shandong China 250101 15 BIOBASE TEL 0531 82373183 FAX 0531 81219880 Input patient information and specimen information sample position is the
30. in accordance with the placement order of the reagents and samples in the interface Enter the number of the Start cuvette Number click the Start button and pop up the hint box FAITH 1020 This interface is to remind users to check whether the reaction cup is washed clean and whether the number of selected initial and last reaction cup is correct After confirmation please click am DOK the instrument begins test If you cancell the above input please click the aal If you want to suspend operations in the testing process please press the pause button Note pause time in the testing process can not be too long If you want to continue the test please press the Continue the instruments will continue to test If you want to cease the operation you can click the Stop button to cancel all tests and retreat to the main interface After confirmation please click sam Ok The status bar will have real time DORR display of the sample state in order to observe the work of the instrument Address No 51 South Gongye Road Jinan Shandong China 250101 21 BIOBASE TEL 0531 82373183 FAX 0531 81219880 When the insrument is to show the test results show it will have real time display of test results absorbance and other information in the results colum There will be a new test results about every 18 seconds If a picture can not show all test results the vertical scroll bar on the right side of the interface c
31. ise the calculation results will appear after all the tests end If there is the V mark in Print inorder check box it means the printing order of the data conforms to the setting of date printing order described by the user in Address No 51 South Gongye Road Jinan Shandong China 250101 23 BIOBASE TEL 0531 82373183 FAX 0531 81219880 data maintenance printing order maintainance is defined in Print Settings of data processing After confirming test result please select All current or range for printing The report format is as follows X X X X X X test report ItemNO 0764 NAME SEX AGE_ NoITEM_ RESULT 1 ALT 13 00 U L 0 00 45 00 9 TG 1 46 mmol l 0 48 1 88 AST 25 00 U L 0 00 45 00 10 Crea 70 0 umol l 36 0 144 0 AKP 83 00 U L 15 0 150 0 TBIL 16 80 umol l 6 0 22 0 IBIL 6 00 umol l 0 00 6 0 TP 74 50 g L 60 0 85 0 Nn Un A Q N DATE 200 Figure 9 print reports diagram 6 1 Parameter Settings of the Tested Item INote In order to prevent the phenomenon of changing the item parameters casually password is set If you do not enter a password you can only edit item parameters that are not closed in the parameter setting bar If you want to edit the closed item parameters you must enter the correct password The original password is 00000000 You can also modify the original password by entering the password changing field to chang
32. lete the selected item in the list first click the item then click the lt button the item disappears from the list of selected items After all of the items are selected click OK button the setting of items portfolio is completed you can edit the items portfolio with the help of Delete button and Edit button 6 4 Parameter Settings of Items for Calculated item Please click the Add button in the column of Parameter Settings of Items for Calculation Please enter the number short name Chinese full name English full name of the item and the short name of the item must be entered and enter the normal low value normal high value number of decimal places If during specimen test all the test items contained in the formula appear After the test is completed the value of items for calculation will be automatically calculated and results will be printed Please edit the formula you can directly enter the item name item must be in the list of selectable items or select an item in the optional item column There can be only the item name and calculation symbols in the formula No other non standard symbols are allowed Please click OK button after setting the item You can edit the item for calculation with the help of button Delete and Edit After deleting items must delete this item in Print item order otherwise you will make mistakes 6 5 Parameter Settings of the Entered Item Please click the Add but
33. lf width of less than 10nm 2nm so that we can collect eight wavelength data at once without any mechanical movement and overcome the defect that the reaction disk of some of the imported products and the filter halo also rotate at the same time so as to ensure measurement accuracy Address No 51 South Gongye Road Jinan Shandong China 250101 4 BIOBASE TEL 0531 82373183 FAX 0531 81219880 3 2 2 Circuit pipetting arm control reagent disc control syringe control circuit data acquisition colorimetric turntable sample disk control Figure 2 The circuit diagram The whole circuit diagram is shown in Figure 2 We adopt a 8051 single chip microcomputer to control the direction speed rotation steps and other functions of a stepper moto and then associated with the computer through the serial bus connection and then the RS 232 interface The rotation and lift of pipetting arm reagent arm mixing arm are mainly controled by two stepper motors and eight position sensors detect the movements and rotational position of sample arm the reagents arm stirring arm liquid level sensor detects the sample and reagent liquid level data acquisition circuit uses eight separate pre amplifier circuit respectively to enlarge the electrical signals of the photoelectric sensor the A D converter converts analog signals into digital signals Colorimetric turntable control circuit stepper motor controls drive cuvette position sensor the
34. mber Sample number conform to the placement of specimens in the sample circle the number of location can be repeatitive Specimen types serum urine and others Address No 51 South Gongye Road Jinan Shandong China 250101 19 BIOBASE TEL 0531 82373183 FAX 0531 81219880 Submission unit the name of the department which sends specimens Patient number If he is the out patients enter patient number patients in hospital enter the hospital number Combination login If you have a number of specimens and each specimen will be tested in terms of the same item in order to facilitate rapid input you can place them continuously on the specimen ring and use the combination login firstly enter the starting specimen number and then enter the start cup No Finally enter the quantity of specimen Then the number of sample specimens and sample number starting Cup are continuously choreograped automatically by a computer Item selection You can two input methods individual item input and item portfolio input Portfolio items are defined in later chapters If you select the individual item you can cllick in the name of the test items press Ctrl to make jumping options or press Shift to make consecutive multiple choice the item is displayed as selected click gt you can double click to add to enter them to the column of test items You also can select other items and enter OK button to confirm If you select the in
35. mena Pour serum or urine to the sample cup and there should be no bubbles in the sample cup 2 reagent preparation Add a sufficient amount of reagent in the kit and it is required that within the validity period quality of reagents should be stable and reliable Address No 51 South Gongye Road Jinan Shandong China 250101 18 BIOBASE TEL 0531 82373183 FAX 0531 81219880 3 clean water preparation It is preferably to use deionized water with conductivity less than 2 0us cm Test procedure Click the Routine operation to enter the following test interface Parameter T Specific Test P Data Management M Service And Adjust x User Y Help H Exit E a ha EA ha b Vy gt ar A Sample Order N Repeat Test R Testing T Report P Click the Sample order menu to enter the following interface Routine Operation S Parameter T Specific Test P Data Management M Service And Adjust X User Y Help H Exit E Lo 3 C0 ICEA e Vy 29a _ t Sample Order PAn EnA Onn anor f EE lll a a a Ld a Click add button and Input the information input the number of samples sample number can only have a unique number within a day without repeative use The patient s name gender age can be entered in the patient information bar patient information can be input while the test report is being printed In the Specimen Information Bar you can edit the sample nu
36. ment panel has three dial sample dial reagent dial and reaction dial there is a text box in the back of each dial label if you input the number click the Execute button the corresponding dial will move to the desired location click the zero button dial reset 9 2 4 A D Reading Click the the A D reading each wavelength signal readings will be displayed in their respective text box if the signal value is not normal indicating that the data channel has fault Click By the wavelength related range is 20000 50000 and oD is close to Address No 51 South Gongye Road Jinan Shandong China 250101 41 BIOBASE TEL 0531 82373183 FAX 0531 81219880 0 0015 9 3 Calibrating the Instrument INote The instrument calibration procedures must be carried out by professionals To avoid damage is done to the machine non professionals we set the password 666666 It s mainly to adjust the position of the sample arm needle reagents needle stirring rod cleaning needle and dial Click Adjustment menu of Service and adjust menu enter the password to enter the interface as follows Fara ae xix 2 l 9 3 1 Horizontal Adjustment of Sample Arm This adjustment corresponds to the reagent arm gt gt horizontal adjustment Click related Rf Through adjusting reagent position the reaction position and sample position we can adjust the horizontal position of the sample arm the reagent position and th
37. n cold storage 2 Computer and printer All operations and control of the instrument are under computer control and it is connected to the computer interface through RS 232 serial port The quality of the computer will directly affect the quality of the system so the computer must be of good quality and its conventional configuration should meet the system requirements To satisfy the need of installing the system software the computer must have the CD ROM The computer is a dedicated instrument not being allowed to do other work in particular not being allowed to play games and install other software which is at the risk of being infected with a virus The printer is used to print a test report and a laser printer is given priority INote The computer should not used for any other purposes Software The instrument is equipped with a set of system software CD ROM which is developed based on the Windows 2000 platform so the Chinese Windows2000 operating system or the superior system must be installed in the computer 4 1 2 Installation of the Instrument 1 Unpacking the Instrument This instrument is a valuable precision instruments Particular attention should be given to lightly packaging and releasing and invertion of the instrument is not allowed in the process of shipping and handling the instrument it is necessary to firstly check whether the box is complete or moistened before installing the instrument if the above situatio
38. n happens it is necessary to notify the staff and they will handle the issue The unpackaging steps are as follows First remove the panel and side panel of the packaging of the wooden box Remove the four screws in the bottom of the backplane Remove shockproof foam packaging Address No 51 South Gongye Road Jinan Shandong China 250101 12 BIOBASE TEL 0531 82373183 FAX 0531 81219880 As the instrument is relatively heavy two or more staff are needed to lift the instrument If the instrument is too wide and can not enter the door the instrument can be tilted slightly but can not be inverted instrument is required to be placed in the level firmly and 30cm with of space at the back of the instrument should be left for maintenance Remove the moisture proof plastic sheeting of the instrument Remove the apparatus used for t fixed attachment of the instrument during the transport see Figure as follow Panel and side panel made of wooden box Figure 5 Schematic diagram of packaging Inspect equipment for any abnormal signs remove the instrument panel to check the circuit board and whether connector is loose if it is loose please fix it 2 instrument installation Install cleaning bucket Install the waste buckets Intake O O Intake wastewater mouth O O wastewater mouth Figure 6 schematic of instrument connecting to the pipes Rear View Connected into the water pipes and waste pipes Install computer and pri
39. nter Address No 51 South Gongye Road Jinan Shandong China 250101 13 BIOBASE TEL 0531 82373183 FAX 0531 81219880 Connect the power cord and RS 232 serial cable Pour deionized water in a bucket ON if Fuse Input power 7 0 0O Cooling switch 0 Output power j RS 232 Main power Figure 7 schematic of computer and instruments connecting with RS 232 line INote The parts of the outlet pipe inserting into the waste container should not be too long 10 cm in length is appropriate so as to prevent the excessive wastewater immersing outlet pipe which will result in poor drainage 4 2 Simple Operation Process 4 2 1 Preparation Before Turning on the Machine Prepare cleaning which will use a bucket of 10 liters or more deionized water Prepare a variety of test reagents and add them to corresponding reagents kit Prepare the samples specimens which will be tested and add them to the sample cup and put them on the sample holder Check whether the power voltage is normal 4 2 2 Turning on the Machine Turn on the power switch which is located on the right side of the maon unit on the back panel above which is refrigeration power switch and under which is the main power switch Turn on the computer power switch and the printer power switch and the main computer Windows interface appears double click the shortcut BIOBASE Sapphire and enter the log in interface enter a user name and password the init
40. ong China 250101 29 BIOBASE TEL 0531 82373183 FAX 0531 81219880 aW Calibration Parameter Leole i Factor Conce value Cup 2013 1 8 18 59 20 2013 1 8 19 49 43 2013 1 30 19 21 06 2013 1 31 18 50 24 2013 1 31 21 27 54 2013 2 1 0 22 31 2013 2 1 13 27 14 2013 2 24 15 50 18 gt Click the item refering to the item list to list the item parameter in the screen Item name and test parameters shows the same The calibration mode can have a variety of options Calibration mode Calibration mode for Sapphire Single standard Double standard Multi standard passing the zero point Multi standard without passing the zero point Formula the formula are as follows Y AX Y AX B Y AO0X n A1X n 1 e AnX Y AOX n A1X n 1 ee AnX B BIOBASE TEL 0531 82373183 FAX 0531 81219880 Figure13 Calibration curve of a single standard Figure14 Calibration curve of doubles tandard Concentration Usually use a single standard is enough Repetitive times Repeat the test several times the result is the average one of the result Number of Standardized ones place several Standardized ones at once One item can have 6 standardized ones Multi point calibration is allowed Specimen Type Serum urine and so on Reagent blank absorbance sample reagents samples and blank absorbance value this data is automatically measured in instrument calibration testing process it needs not to be input
41. parts to modify if one wants to cancel the change click Cancel button If you want to save your changes then click the Save button If you want to delete test item parameters select the item in the list of items column click the delete button and then remove the item parameters If you want to add the test item click the Add button to enter the test parameters and save the input 6 2 Parameter Settings of Special Items Click the special item parameter settings menu of the Item setting in the main interface to the following interface Routine Operation S Parameter T Specific Test P Data Management M Service And Adjust X User Y Help H Exit E 3 e Sm to EB 98 ee T gt la A Specific Parameters FOTN ENS ORT Chem 12 SURE ne HbA1C HbA1C HbA1C MPAA CET re a a cl High 5 2 EA Address No 51 South Gongye Road Jinan Shandong China 250101 27 BIOBASE TEL 0531 82373183 FAX 0531 81219880 6 3 Parameter Settings of profile item Click the Add button in the column of items portfolio parameter settings enter the number the short name full Chinese name full English name of the item and the short name of the item must be entered click the item in the optional items and the background color of the item turns blue click the gt button to add items to the list of selected items and use the same method to select other items If you want to de
42. position number you choose on sample disk Select the test item and cllick in the name of the test items press Ctrl to make jumping options or press Shift to make consecutive multiple choice the item is displayed as selected click gt you can double click to add to enter them to the column of test items You also can select other items and enter OK button to confirm Repeat the above steps When the entry is completed please exit the routine test login screen Click Testing or to enter the following test interface Routine Operation S Parameter estiP Data Management M lt And Adjust User Help H E tE Marc sallle a a Testing Aen Beas td 8l HA FORE l seesi gt ih Stop Refreshing Stop alarm sound Flag s Detail osan pause TR Continue Check reagents and samples in accordance with the place order of the reagents and Sat ek in the interface Enter the number of the first cuvette and click the After confirmation please click OK button to start the test Instrument starts to test the sample and the information of the sample is revealed in the instrument column 4 2 5 Processing and Printing of the Result Address No 51 South Gongye Road Jinan Shandong China 250101 16 BIOBASE TEL 0531 82373183 FAX 0531 81219880 In the sample test menu please click Report or Routine Operation S Parameter T the sie Gale LZ ie
43. put of the item portfolio you can select the name of the item portfolio to be tested in the the item portfolio bar Click on the item the item is displayed as selected click the gt and add it to Selected Item column if you want to delete a test item please click the test item in the Selected Item column click the lt to delete the test item Repeat the above operation to input the specimens You can edit the information entered In the Lonin Column you can select a sample number for inquiries and it will reveal the information of patient and test items You can use Edit or delete button to edit and delete the displayed content If the information is correct please enter OK button for conformation Note The patient information can be entered here and can also be input while printing a test report When the input is completed please exit the Sample Input interface 5 2 2 Test Click on the Testing or to enter the following test interface Address No 51 South Gongye Road Jinan Shandong China 250101 20 BIOBASE TEL 0531 82373183 FAX 0531 81219880 Routine Operation S Data Management M Serv vje lajt ile aaa ific Test P r Help H T nae pis s Testing x Sam no item OD Resutts unit Fao Pe e585 aaeseseedaaeeee gt 4 TT 1 Stop Refreshing Stop alarm sound Flag s Detail start pase Continue Check reagent and sample
44. rs to test various components of the instrument so as to identify failures Data processing module can check the patient s test results QC results etc and carry out mathematical statistics calculate daily average and draw trend mapping to provide valuable statistical information to the Clinical Laboratory records of equipment failure can record the fault information of the instrument while working and provide maintenance information to maintenance personnel Instrument maintenance and maintenance module are to provide staff with a means of detection instrument Routine maintenance can provide routine maintenance of the instrument and calibrating the instrument can test the instrument s moving parts and optical signal SCM software is compiled by using assembly language and is used to manage coordination operation of each motor of the management data acquisition and other work 3 4 Structure Biochemical analyzer consists of the main unit of analyzer computer including the main unit and monitor the Windows 2000 or more superior operating system exclusive software and printers etc It is suggested to buy the computer and printer which meet the national standard Minimum configuration Computer frequency should be no less than 500MHz RAM should be greater than 128M Address No 51 South Gongye Road Jinan Shandong China 250101 7 BIOBASE TEL 0531 82373183 FAX 0531 81219880 Hard disk capacity should be greater than
45. t P Data Management M Service And Adjust X User Help H Exit E ea BAe l Reaction Curve L Data Maintenance M 1 20803141E ALP i Standard QC Cha ALP 208031E get Value 93 Select the test item in the Drop down list enter the start and end dates Data date and batch number of an item within a period of time is displayed in the QC value column If several quality controls are made in the same day we need to choose an appropriate data as a quality control chart parameters the default value is the first data the statistics column automatically calculates their average value SD CV Quality control chart shows quality control graphics click Print Quality Control Chart to print 8 2 Reaction Curve Monitoring Address No 51 South Gongye Road Jinan Shandong China 250101 38 BIOBASE TEL 0531 82373183 FAX 0531 81219880 During test each test item the instrument read a set of data on eight wavelength every circle for each test item There are a total of 40 point value for each tested item We can observe the reaction of the whole process to understand the correctness of the results Click the reaction curve of data processing menu to enter the following interface EE i 5 1015 20 25 30 35 40 45 50 Click the Delete button to delete all the data of selected date INote Be careful to use the deleted data data can not be recovered Click Date button select
46. t accredited calibration results in date list of all calibration and display it in the text box If you want to delete a calibration data in the list you can select the data click delete the calibration button If you want to modify the calibration parameters please press Edit button If the calibration results are right you can click the OK button to save the calibration results Close the page and returned to the calibration order interface Select the calibration item in the item list column method of selection is the same as that described earlier If the data is entered correctly close the page then fileDialog as below a ia g PL gt e al Calibration Parameter Address No 51 South Gongye Road Jinan Shandong China 250101 32 BIOBASE TEL 0531 82373183 FAX 0531 81219880 Click the 2 sc OK and then open the testing or then click start The os calibration test will start In the test process you can click the Stop button to stop the test After the test is completed you can enter the calibration parameters to see results of the calibration 7 2 QC Test In order to monitor the accuracy of test results it is sometimes necessary to test quality control of some specimens There are a variety of ways of doing QC test the first method is in ordinary sample test you can observe whether the test results is within the quality control ran
47. t consists of two sub menus the sub menu of parameters of tested item mainly sets the sample volume reagent volume the analysis wavelength test methods and other parameters of each tested items parameter settings of special items is to set a formula based on which test results has been calculated and form a new item results combinated items Address No 51 South Gongye Road Jinan Shandong China 250101 6 BIOBASE TEL 0531 82373183 FAX 0531 81219880 settings is to facilitate the item input Based on clinical requirements routine testing items can be combined into a new item and we can enter the new combinated item name while inputting these items Special inspection is the exclusive test in addition to routine test and it can test the standard samples draw standard curves test quality control specimen describe quality control diagram and other work it can also test the instrument performance such as linear measurement absorbance measurements the repeatability measurements which has facilitated the identification of the measurement work and special needs of the users The layout of each test reagents used in the test means the position of reagents on turntable is set so that the instrument can accurately find the required reagents Instruments can measure the amount of each reagent before the item is tested and tell the operator whether he needs to add reagents Maintenance and repair of sub menu facilitates maintenance enginee
48. the date Select the types of specimens that you want to query in samples calibration and quality control If you choose specimens selected samples to display the number of samples in the sample column within that day select the correct number of samples the samples tested in the project displays the list of items If you want to observe the test data click the Data button the interface displays all the absorbance value of main wavelength auxiliary wavelength and the difference between the two click the data button to exit Repeat the above process you can query calibration and quality control click upper right corner x to exit the response curve monitoring interface 8 3 Data Maintenance Address No 51 South Gongye Road Jinan Shandong China 250101 39 BIOBASE TEL 0531 82373183 FAX 0531 81219880 Data maintenance is a module to effectively maintain the printing report and its datas click Data maintenance of Data Maintenance menu to enter the following interface 1 GGT 4 ALP 9 GLU 10 CHOL 14 HDL C 16 LDL C EA gt Refresh In the Print Settings column you can enter the name of the hospital which produced the report place print order In the data set column you can input examining physician units of measurement inspection departments clinical impression inspection departments and other contents INote 1 When arrange the item print order it should be arranged all the it
49. ther the light source lamp is burned out and the light source lamp is of 12V 20W Replace it if it is broken Address No 51 South Gongye Road Jinan Shandong China 250101 45 BIOBASE TEL 0531 82373183 FAX 0531 81219880 10 3 Reagent Sample needle not Washed Check whether the water pump is working If the pump is normal please check the waterway connecting pipe If it comes off please connect the pipeline And then if the pipe gets clogged replace the pipe lf the water pump can not work correctly replace it 10 4 The Amount of Sample Reagent is not Accurate Check whether the syringes and the pipes leak and whether head of the pipetting needle gtes clogged and then replace them with new pipe or syringe 10 5 Position of Sample Reagent needle is Offset Adjust the position of sample reagent needle through the instrument adjustment software 10 6 Result of One item is not Accurate Check the reagent and adding situation And observe whether other items are normal with the same wavelength If not normal replace the light filter Address No 51 South Gongye Road Jinan Shandong China 250101 46 BIOBASE TEL 0531 82373183 FAX 0531 81219880 Note If the fault can not be ruled out please contact maintenance engineers of the company Contact information please see the last page of the manual Suggestions Accuracy of test results from automatic biochemical analyzer is mainly decided by two factors First
50. ton in the column of Parameter Settings of entered Items Please enter the number short name Chinese full name English full name of the item and the short name of the item must be entered and enter the normal low value normal high value number of decimal places Please click OK button after setting the item You can edit the item for calculation with the help of button Delete and Edit Address No 51 South Gongye Road Jinan Shandong China 250101 28 BIOBASE TEL 0531 82373183 FAX 0531 81219880 Note The entered item of the printed report must be maintained in this column If there is no item in this column the entered data can not be printed 7 Specific test 7 1 Calibration and QC Some test items need calibration click the specific test and choose calibration order to display the following interface Routine Operation S Parameter T Data Ez Service And Dial User Y Help H Exit E Calibration Order 0 Reagent Status R Washing and Blank W Reading Absorban H Routine Operation S Farameter T Specific Test Data Management M CACAR ial to User Y Help H Exit E lal Lele 4 t Calibration Order Calib Item DBIL OXI TP TG In detection mode select the calibration mode Calibration item parameter need to be done before calibration procedure click calibration parameters button to display the following interface Address No 51 South Gongye Road Jinan Shand
51. ts functions the analyzers we produce approach or reach the level of their foreign counterparts BIOBASE series of discrete automatic biochemical analyzers use discrete cuvettes which are segregated and have no cross contamination between each other significantly improving the precision and speed of the instrument Overcoming the defects such as the relatively low analysis speed of flow cuvette serious cross contamination and low accuracy so these series of analyzers arewelcomed by the majority of hospitals 2 3 Users BIOBASE Sapphire is operated by professional eople in accordance with the munual 2 4 Security The following sections will introduce the note in terms of security electronics and other relevant potential dangers 2 5 General Prevention When operating BIOBASE Sapphire the user should be strictly in compliance with laboratory practice and must wear suitable protective clothing and rubber gloves A During the operation of BIOBASE Sapphire the sample arm move quickly so the user should not place the hand in the work area of the moving parts so as to avoid accidental injury Meanwhile the user should not rely on BIOBASE Sapphire or tilt it to avoid potential personal injury or equipment damage Address No 51 South Gongye Road Jinan Shandong China 250101 2 BIOBASE TEL 0531 82373183 FAX 0531 81219880 2 6 Electrical Safety Precautions When disassembling the equipment components or circuit boards t
Download Pdf Manuals
Related Search