Thermo Scientific SRS Pro Solvent Recycling
Contents
1. 020487 7070 nl info thermofisher com www nl fishersci com Portugal tel 21425 3350 fax 214253351 pt fisher thermofisher com www pt fishersci com Suisse Switzerland t l 056618 41 11 fax 056618 41 41 info ch thermofisher com www ch fishersci com Thermo Scientific SRS Pro Solvent Recycling System User Guide v1 2009 Thermo Fisher Scientific Inc All rights reserved All trademarks are the property of Thermo Fisher Scientific Inc and its subsidiaries Part of Thermo Fisher Scientific SCIENTIFIC2. Description Principle of Operation reduce mobile phase consumption by up to 90 by redirecting untainted mobile phase to the solvent reservoir during isocratic HPLC operation With a modern compact design and innovative features SRS Pro brings a fresh approach to solvent recycling No power adapter is required as the solvent saver is powered directly from the chromatography data system PC through a USB connection User friendly software is provided to configure the system parameters and also includes on line monitoring and audit trail facilities Analog input to SRS Pro allows for unipolar or bipolar operation of the device within a range of 1V An analog to digital converter facilitates further evaluation by the built in processor TTL contact closure for the device can be configured as Start auto zero or valve position control input Thermo Scientific SRS Pro continuously monitors the output signal of the chromatographic detector recycling the mobile phase to the solvent reservoir when the baseline is below a certain preset threshold Operation of SRS Pro is illustrated in Figure 1 If the input signal level exceeds this threshold value a SRS Pro redirects the eluent flow to waste with a delay taking account of the transport time from the detector to the switching valve When the signal returns below the threshold b SRS Pro again waits for the transport delay and then switches the mobile phase back to the reser
3. Thermo Scientific SRS Pro Solvent Recycling System Users Guide 66001 001 Part of Thermo Fisher Scientific SCIENTIFIC Chromatography Resources Our Chromatography Columns and Consumables catalogs helps you find all your chromatography needs in a single resource To order your copy visit www thermo com catalog Our bi monthly Separated By Experience newsletter keeps you up to date on the latest technical and product information of interest to chromatographers Subscribe today at www separatedbyexperience com Beyond the catalog our Thermo Scientific Chromatography Team shares its extensive expertise through our web based Chromatography Resource Center The Chromatography Resource Center accessed at www separatedbyexperience com provides technical support applications technical tips and literature to help move your separations forward quickly and easily f Separated by Experience re 7 a a Es BN E omomor src these new HPLC wnd SPE ary ald aa icid SCIEN TLE TC A Newsletter for Chromatographers sortons whatsNew Anaivies Announcements January 2007 Issue 3 gt Send to a friend Welcome to the Separated by Experience enewsletter eaturing New Solutions New Products and New Ideas to make your chromatography easier issue request your free subscription today Spotlight Solutions Productivity Solutiot pad EE Separation moa ace n of Complex Amino e you cas eas Acid Der
4. d using the provided software although it may also be performed using any terminal program e g Windows Hyperterminal After connection of SRS Pro to the system PC the operating system will recognize the hardware and install the necessary virtual com port driver Use the Windows hardware manager to detect com port number reported Thermo Fisher Scientific Thermo Fisher Scientific as USB Serial Port It is necessary to set this com port number later in SRS Pro software setup Start the SRS Pro application It is possible that an error message Invalid port number may be seen the first time the application is opened Ignore it by clicking OK and continue with the setup A new recycle icon will appear on the Windows task bar It is now possible to open the local menu and select Setup by right mouse clicking on the icon The desired com port can now be selected as illustrated in Figure 6 If the appropriate com port IS currently unavailable click the Disconnect button Then click Save button The solvent recycler is now ready for communication with the control application SRS Pro Setup Com port i Initialize Figure 6 Selecting the com port Before using SRS Pro the Threshold and Delay parameters need to be correctly set in accordance with the properties of the chromatographic system The SRS Pro system status window can be activated by right click on saver task bar icon and selecting th
5. e Show Status option The threshold value is set by entering the desired value into the threshold edit box 200 mV has been entered as shown in Figure 7 and selecting the Set Threshold button marked with his icon fi The value is now stored in SRS Pro nonvolatile internal memory Specifications Computer Requirements Thermo Scientific SRS Pro RECYCLE 1000 mv Threshold r Delay e UU U Figure 7 Setting the threshold level In a similar manner the delay value is set by entering the desired value into the delay edit box and selecting Set Delay button marked with icon amp A typical setting will be between O and 5 seconds depending on tubing length and flow rate To zero the system wait until detector baseline is stable Zero your detector signal and then select the Auto Zero icon on the speed bar of SRS Pro status window e Powered from PC USB port e Input range 1V optimized for integrator detector output e 12 bit analog to digital converter e 1 Hz data rate e LED indication of WASTE RECYCLE positions e Manual WASTE RECYCLE control e User configurable TTL contact closure input e Compatible with any HPLC detector e Wetted material PEEK e Connection 28 Flat Bottom e Maximum pressure 30 psi 0 2 MPa e Only two operating parameters Threshold Transport Delay e Easy Plug amp Play Installation e Drivers and Software Included Personal computer data system running Micr
6. is necessary to setup analog output within the instrument software prior to using SRS Pro _ a am all 12 QQ GIL ZE a gt op I gt lt F Figure 4 Connecting the start cable to Thermo Scientific Surveyor or Accela detector Initial Setup If using an Agilent detector connect the analog signal output on the rear panel to SRS Pro using the BNC analog input cable provided Set the analog output to 1 Volt FS in the instrument software Interface board SS a ae 7 E a Analog signals es APG remote o RS 232C CAN HP IB P ower Configuration switch Figure 5 Connecting the start cable to Agilent detector If auto zero of SRS Pro is required the START input should be connected to the contact closure of the HPLC autosampler This contact closure must be activated at the moment of injection The default function is auto zero If the output of the autosampler is polarized e g open collector output respect the polarity of START input it has an internal pull up resistor Connect the USB cable of solvent recycler to the PC ensuring that the software and drivers have already been installed SRS Pro has built in USB interface Communication with the system PC running MS Windows operating system is accomplished via virtual com port driver using simple text protocol It is recommended that communication between the system PC and SRS Pro is performe
7. iv on 5 pi ment pro with Fa ie red application uses a ur solutio that do the E dir wate screen adenine aS w you a Productivity hat ac tely and efficiently b separa jentifies an asur ci fa combine Thermo a Scientific GCM s sys and con mention single alidated ure immediate success aus Increasing Throughput in oe i s by aha Th Using 1 9 um Particle Pac What s New This IMSC 2006 posi nae des a oot ethe Ne e as at the Chromatography speed and resolutio ee seis ans sing 1 9 Res e Center um particles and to prove eect ity v alternative column chemistries Read more ny m Chromatography Resource Center ea iE pa eA rce C is the of Thi eee duress pia Arar and Con mables H Seas a wes iors ration method say gta and ONS Maan atesi e ratograpny Saas T Thermo Fisher Scientific Introduction Table of Contents Thermo Scientific SRS Pro solvent recycling system can reduce mobile phase consumption by up to 90 This is achieved by continuously monitoring the output signal of the chromatographic detector recycling the mobile phase to the solvent reservoir when the baseline is below a certain preset threshold Product description 2 Principle of operation 2 Getting Started 4 Tubing Connection 4 Software Installation 4 Electrical Connection 4 Initial Setup 6 Specifications 8 Computer Requirements 8 Contact Information 9 Product Thermo Scientific SRS Pro solvent recycling system can
8. osoft Windows 98 2000 XP Vista 32 with one free USB port Thermo Fisher Scientific Contact Information To Place an Order USA amp Canada T 1 800 532 4752 F 1561 688 8731 E analyze us thermo com United Kingdom T 44 0 845 702 3964 F 44 0 1707 391 311 E enquiries chromacol com France T 33 0 1 60 92 48 00 F 33 0 1 60 92 49 00 E analyze fr thermo com All Other Enquiries T 44 0 1928 581 000 F 44 0 1928 581 078 E salesorders columns uk thermofisher com For Technical Support USA amp Canada T 1 800 532 4752 E techsupport analyze us thermo com Thermo Fisher Scientific Japan T 81 45 453 9129 F 81 45 453 9199 E analyze jp thermo com Switzerland T 41 0 56618 41 11 F 41 0 56 618 41 41 E into ch thermofisher com Germany T 49 0 6103 408 1140 F 49 0 6103 408 1111 E analyze de thermo com Africa Asia Europe Latin America amp Middle East T 44 0 1928 581000 E techsupport columns thermo com Belgique Belgi t l 056 260 260 fax 056 260 270 be fisher thermofisher com www be fishersci com Espana tfno 91 380 67 10 fax 913808502 es fisher thermofisher com www es fishersci com n m EERS France t l 03 88 67 53 20 fax 0388671168 fr commande thermofisher com www fr fishersci com Fisher Scientific Italia tel 02953 28 258 fax 02953 27 374 it fisher thermofisher com www it fishersci com Bonini Thana Fisher ticenific Netherlands tel 020487 7000 fax
9. the 3 way valve marked as WASTE should be connected to the solvent waste bottle Installation of the software package should be performed prior to connection of SRS Pro to the computer To install the software insert the software CD into the drive on your computer The installation process will normally Start automatically If the auto play function is disabled run setup exe from the root folder of CD Follow the instruction of the installer Connect the SIGNAL input of SRS Pro with the integrator 1V Full Scale output from the HPLC detector using the cable provided as illustrated in Figures 3 to 5 Thermo Fisher Scientific Thermo Fisher Scientific If using a UV6000 detector locate the OUTPUT screw terminal on the rear panel as shown in Figure 3 above C Using the standard analog input cable connect the blue wire to the CH1 position and the black wire to CH1 position Channel 2 can be used alternatively It is necessary to setup analog output within the instrument software prior to using SRS Pro ch 2 5V EVENT READY RUN B SPARE COM COM cos SaS START ZERO SPARE COM COM COM Blelelelele Figure 3 Connecting the start cable to Thermo Scientific UV6000 detector If using Surveyor or Accela detector again use the Standard cable supplied Connect the blue wire to the CHA 1V output and the black wire to GND A positions Channel B can be used alternatively It
10. voir TO ensure consistent operation in an automated environment zeroing of the signal input at the point of injection can be performed by connecting the autosampler injection marker signal to SRS Pro Thermo Fisher Scientific Thermo Fisher Scientific i WASTE P RECYCLE THRESHOLD Figure 1 SRS Pro Principle of Operation In order to protect the integrity of the mobile phase supply SRS Pro is designed to recycle the mobile phase only if switched on The normal position of the 3 way valve is waste Therefore in case of power failure the valve remains in the waste position and the mobile phase in the reservoir remains uncontaminated Getting Started Tubing Connection Software Installation Electrical Connection Unpack the SRS Pro Solvent Recycler The box should contain the following items SRS Pro Solvent Recycler Connectors Qty 3 Ferrules Qty 3 Electrical cables Qty 2 pFTE tubing User manual Quick start guide System CD SRS Pro can be connected to the HPLC system using 1 16 PTFE tubing and flange free fittings Ferrules must be placed in the proper position against the nut as illustrated in Figure 2 Figure 2 Tubing connection The mobile phase output from the detector should be connected to the common port of the 3 way valve of recycler marked as DETECTOR The outlet port of the 3 way valve marked as RECYCLE should be connected to the mobile phase reservoir The outlet port of
Download Pdf Manuals
Related Search