DOWNLOAD NOW ALC-601 Laser Combiner The Andor Laser
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1. non condensing e Operating Altitude Up to 2000m e Storage Temperature 0 C to 50 C ambient OHS502497 Ce ALC601SS 0615 R1 Power Requirements e Mains Power supply 100 240 VAC 50 60 Hz e Power consumption 350 W Max 15W MPU Controller2. et al 2005 http www conoptics com wp content uploads 2013 09 Alternating Laser Excitation of Single Molecules pdf the AOTF can be left open on multiple simultaneous channels and the ALC Ultra fast driver board is available for direct modulation up to the laser maximum 150 MHz for some diode lasers Left Time lapse images showing mitosis in HeLa cells time in hr min This experiment illustrates how minimal exposure combined with laser spinning disk microscopy preserves live cell health and function Image Courtesy of Alexey Khodjakov Division of Translational Medicine Wadsworth Center New York State Department of Health Albany NY ALC 601 laser options The laser wavelengths and powers supported are outlined in the table below An ultra fast driver module UFDM is available for applications requiring 10 s MHz switching rates Wavelength nm Power Rating mW 405 100 445 40 50 488 50 60 488 50 100 150 200 491 5 50 100 Slee 50 100 150 532 50 100 150 200 300 561 2 5010015020015001 593 6 50 100 640 100 659 6 400 Above Maximum intensity projection of z series from Zebrafish retina highlighting nuclei blue green and red sensitive cones green and 2 different types of bipolar cells red amp yellow Courtesy of Tim McGinn Stenkamp Lab University of Idaho USA Wavelength variation nm depends on laser type 0 3 2 5 denotes on special requ
3. 01 with MPU Top panel 448 7 17 67 r 592 9 23 34 487 1 19 18 4 482 4 18 99 Front panel top and rear panel below Laser TTL Control SMB 425 5 16 75 q Compact flexible and robust AN ple d ALC 601 6 line laser combiner an company PCU O O O OOO Ow O O O O O O O ge MPU Controller ALC 601 Supplied Components 1 x ALC 601 supplied with purchased lasers installed ALC enclosures are 19 rack mount capable An optional wheeled rack system is available 1 x PCU 100 precision controller with TTL I O and AOTF controller 1 x Single or multi mode optical fibre suitable for selected application Borealis requires multi mode 1 x PCI DAC card and D 37 cable for PC control interface 1 x USB cable Power cords for local mains supply 1x User Manual Optional Ultra fast driver module UDFM for high speed switching integrated into ALC enclosure MPU multi port head integrated with ALC MPU controller Additional one or two single mode optical fibres for selected MPU FORD E INSTRUMENTS The Business of Science Software Compatibility e Andor iQ Micro Manager MetaMorph QuickPALM Software Development kit SDK available on request Regulatory Compliance e EU EMC LV Machinery RoHS Directives e Laser safety compliant for IEC 60825 1 and CDRH 21 CFR 1040 10 Class 4 under special request Compact flexible and
4. Compact flexible and robust 6 line laser combiner ALC 601 ANDOR company IM Flexible configuration up to 6 lines v Supports multiple devices covering a broad range of applications WM High stability and robust design delivers optimal performance a gt 5 D gt O O Q T D a 3 gt O 5 Features and Benefits Next generation laser combiner Enhanced power delivery and stability at single mode fibre outputs Borealis compatible Use multi mode fibres with homogenizer for high intensity imaging Multi port fibre switch Supports complex microscopy systems Direct laser TTL control For user defined precision control Linearised power output Corrects for AOTF non linearity Power down lasers Switch off unused lasers to extend lifetime Power threshold protection Do not exceed power limit for delicate fibres Class IIIB compliant version Support for up to 500mW Class IV gt 500mW version For super resolution and related applications Highly flexible and configurable platform System may be built to your specific requirements Customer Special Request CSR system Specialised and experimental configurations are available using our CSR system The multi line laser source delivering flexibility for demanding application needs The Andor Laser Combiner ALC is now in its 3 generation delivering a highly configurable laser delivery package to meet a wide variety of
5. DM simultaneously TTL Software selection of individual laser control mode 3 x BNC 500 Inputs with OR logic Via PCU Active Blanking AOTF controlled shutters all output Digital Inputs 8 x BNC 500 TTL Via PCU Digital Outputs 8 x BNC 500 TTL Via PCU Power Supply Requirements Mains 100 240V a c 50 60Hz Power Consumption 350 W Max 15W MPU Controller Independent Software control of each laser to greatly extend laser life Laser Standby Mode 90 seconds warm up time after re enable AOTF controlled Linearised output O 100 0 1 resolution Laser Power Control Linearity 5 AOTF controlled up to 6 lines with independent and asynchronous control rT ay Cah Absolute maximum incident laser power 5 W q Compact flexible and robust AN ple R ALC 601 6 line laser combiner an company Mechanical Specifications ALC 601 Dimensions WxDxH 483mm x 530mm x 184mm 483mm x 593mm x 210mm 4U 19 Sub rack BS EN 60297 Aluminium Construction ALC 601 Enclosure and Mounting Format Andor Revolution XD 19 Rack mount Cabinet Optional Rubberised feet allow for bench top mounting ALC 601 Weight 38Kg Max 6 Lasers 42kg Max 6 Lasers PCU Dimensions WxDxH 483mm x 316mm x 133mm 3U 19 Sub rack BS EN 60297 Aluminium Construction PCU Enclosure and Mounting Format Andor Revolution XD 19 Rack mount Cabinet Optional Rubberised feet allow for bench top mounting PCU Weight 8kg MPU Controller Dimensio
6. est e e 2 q Compact flexible and robust AN ple R ALC 601 6 line laser combiner an company Specifications Optical Specifications Up to 6 Diode Lasers 5 Diode 1DPSS OPSS Lasers Laser Configurations 4 Diode 2DPSS OPSS Lasers 3 Diode 3DPSS OPSS Lasers 1 Diode Laser 640nm 4 DPSS OPSS Lasers 500mW Maximum for Class IIIB raser CMAN mol iba COURET Class IV gt 500mW emission version available under CSR Fibre coupled Power Stability lt 2 per C RMS Noise 0 10Hz 10MHz se Output Polarisation Extinction Ratio Typ Fibre Optic Type Fibre Output Connector gt 100 1 Single mode polarisation maintaining stainless steel armoured cabling or multi mode used with Borealis illumination Selectable FC AFC FC APC FC PC Rise Fall Time lt 2 uS NE nc onuneiro Extinction Ratio 50 dB fibre end gt 60dB Signal Lag lt 2 US Digital Modulation Rise Fall Time lt 20 ns Diode Lasers Max Freq 150 MHZ Digital Modulation Rise Fall Time 18 2 uS OPSS Lasers Max Freq 50 kHz MPU Switching Speed optional N A lt 2 a Pa ta MPU Max Switching Freq Optional N A 100 Hz Electronic Specifications Control Interface USB2 0 and 37 Pin D sub connector PCI I O Card included 6 x SMB Connectors 500 TTL PASM pee Wita l tts SITE Allows independent asynchronous control 1 x BNC 500 Distributes the modulation signal to up to 4 diode lasers FLIM Modulation Option UF
7. imaging application needs Our long standing expertise in laser combiners means that you can be certain of owning a robust device with optimum performance both optically and mechanically and which delivers a highly stable output Laser safety is paramount in the design of the ALC 601 which is primarily supplied as a Class IIIb CDRH compliant device up to 500mW and includes full interlock connectivity Offering up to 6 laser lines from 405nm up to 660nm across a broad range of power options you can configure the ALC 601 according to your budget and application needs Laser line selection and power control are managed though an accousto optical tuneable filter AOTF resulting in laser switching and incremental power control in the microsecond range Enhance the ALC 601 with a multi port unit MPU to provide high speed switching between two or three outputs to support multi mode imaging For example use a three port MPU for multi point confocal TIRF illuminator and active illumination for photo bleaching photo switching or uncaging Included with the ALC 601 is the Precision Control Unit PCU which provides 8 TTL input and 8 TTL output channels as well as AOTF control This provides the functionality with the appropriate software to send and receive trigger commands to peripheral devices as part of an imaging experiment Additional TTL connectivity is provided for direct laser modulation if desired and an ultra fast driver module UFDM can al
8. ns WxDxH 483mm x 324mm x 95mm 2U 19 Sub rack BS EN 60297 Aluminium Construction MPU Controller Enclosure and Mounting Format Andor Revolution XD 19 Rack mount Cabinet Optional Rubberised feet allow for bench top mounting MPU Controller Weight 5kg General Specifications Andor iQ MetaMorph Micro Manager LabView Driver available on request Control Software Operating Temperature 23 C 5 C Indoor use only Operating Relative Humidity lt 70 Non condensing Storage Temperature O 50 C Operating Altitude Up to 2000 m Compliance Specifications Certification CE Compliant CDRH Registered Class Illb IEC 60825 1 and CDRH Class IV IEC 60825 1 and CDRH available under special request RoHS Compliant Yes Key operated master switch shrouded fibre connection laser safety interlock kit inc remote interlock connection Classification Laser Safety Features Borealis high throughput and uniform illumination Andor EMCCD and scientific CMOS with CSU X and CSU W the ultimate in detection Borealis enhanced CSU X Andor iXon EMCCD Andor sCMOS Find out more about Borealis at www andor com microscopy systems To find out more about Andor s range of EMCCD and scientific CMOS revolution borealis detectors please see www andor com scientific cameras q Compact flexible and robust AN ple d ALC 601 6 line laser combiner an company Product Drawings Dimensions in mm inches Standard ALC 601 ALC 6
9. robust 6 line laser combiner ANDOR company Order Today Need more information At Andor we are committed to finding the correct solution for you With a dedicated team of technical advisors we are able to offer you one to one guidance and technical support on all Andor products For a full listing of our regional sales offices please see Nk lalofo eo palfoTo ajrc Toji Our regional headquarters are Europe Japan Tokyo Phone 81 3 6732 8968 Fax 81 3 6732 8939 Belfast Northern Ireland Phone 44 28 9023 7126 Fax 44 28 9031 0792 China Beijing Phone 86 10 8271 9066 Fax 86 10 8271 9055 North America Connecticut USA Phone 1 860 290 9211 Fax 1 860 290 9566 Footnotes Specifications are subject to change without notice 1 All specifications are typical Requires optional ultra fast driver module UFDM ALC 601 models are registered CDRH and IEC Class 3B or Class 4 according to laser selections Installation service and upgrade should be performed by qualified personnel All local safety standards should be followed by users o oF de po o If your specific requirements are not covered in this document please contact your sales channel We will certainly consider special requests Operating amp Storage Conditions OHSAS 18001 Occupational e Indoor use only aragement anao e Operating Temperature 18 C to 28 C ambient FM40523 EMS91062 e Operating Relative Humidity lt 70
10. so be added for applications such as FLIM Fluorescence lifetime microscopy and ALEX Kapanidis et a 2005 Key Specifications Max number of lasers 6 405 660 8 TTL input and 8 TTL output channels Wavelength range nm TTL control interface Integral AOTF clean emission lt 2 us wavelength switching Active Laser blanking 2 us on off times Linearized power control Linearity lt 5 FSD Resolution 0 1 Optional multi port unit 2 3 ports switching time lt 2 ms all ports Optional ultra fast driver up to 150 MHz TTL modulation High power option gt 500 mW Class IV vw 4 ANDOR company Laser modulation options ALC 601 uses an integral AOTF for control of all laser lines and this provides significant benefits o First it provides high speed and precision across the full intensity range 100 0 1 0 1 steps making the ALC 601 an ideal product for complex imaging needs like localization microscopy and minimal exposure microscopy O Connell et al 2009 hito Avww ncbi nim nih gov pmc articles PMC2762104 e Second the AOTF provides fast gating for Active Laser Blanking minimizing specimen exposure and readout artefacts when combined with ultra sensitive EMCCD and rolling shutter sCMOS cameras e Third ALC 601 delivers extremely rapid wavelength switching 2 us and simultaneous multi band excitation Finally for experiments requiring ultra fast switching like alternating laser excitation ALEX Kapanidis
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