TSC ThermoShaker user manual (English)
Contents
1. ee na see 8 ist Reaction Hune TIME 9 21 2 MAKING M ee ee 9 Zl Reaction Temperature T C zen 9 Fro am beXeoHtlo suia colon e aao DER dase eae 9 8 MAINTENANGE a a a aa nenn ehe 11 CO ANN G en EN 11 8 2 RUBBER BELT 11 9 jeje T ON O e 12 10 SERVIGE a 13 11 EQUIPMENT DECONTAMINATION 14 12 NOTE FOR DISPOSAL OF ELECTRIC ELECTRONIC WASTE 16 13 NOTO coc ER 17 14 EC DECLARATION OF CONFORMITY EU KONFORMITATSERKLARUNG 18 SWARRANTY ee ee HQ 19 2 Safety The following symbols mean A 7 05 rm y Caution Read these operating instructions fully before use and pay particular attention to sections containing this symbol Caution Surfaces can become hot during use Caution Instructions for handling Always observe the following safety precautions Do not check the temperature by touch Use a thermometer Do not touch surfaces which become hot during high tempera2. The platform motion can be stopped at any time by pressing the Shaker Start Stop button In this case the program and the platform motion stop the timer is set back to zero and switches into the STOP mode Press the Shaker Start Stop button to repeat the operation with the same time and speed Attention At the end of the set time period the platform movement is stopped A N automatically but the heating can be stopped only manually by reducing the temperature with the VW T C key Fig 5 3 lower button till the OFF sign appears in the upper line of the display At the end of operation switch off the unit by using the on off switch at the rear side of the TS1 Fig 4 10 8 Maintenance All products covered in this manual are designed to comply with IEC61010 1 and can be flash tested As they are fitted with radio frequency interference suppressers it is recommended that only a D C test is performed No other routine service is required 8 1 Cleaning The case can be cleaned with a damp cloth after disconnection Do not use liquids that contain concentrate organic solvents alkali or acid nor abrasives Standard ethanol 75 can be used for disinfection Attention Disconnect the unit from the power supply socket Before using any decontamination or cleaning method except that recommended check with our Service Department that the proposed method will not damage the equipment 8 2 Rubber belt repla
3. ated it is possible that Biometra will be forced to refuse to accept the device e The sender of the repair order will be held liable for possible losses resulting from insufficient decontamination of the device Please enclose a note which contains the following a Senders name and address b Name of a contact person for further inquiries with telephone number 13 11 Equipment Decontamination Certificate To enable us to comply with german law i e S71 StrlSchV 817 GefStoffV and 819 ChemG and to avoid exposure to hazardous materials during handling or repair please complete this form prior to the equipment leaving your laboratory COMPANY INSTITUTE ADDRESS PHONE NO FAX NO E MAIL EQUIPMENT Model Serial No If on loan evaluation Start Date Finish Date Hazardous materials used with this equipment Method of cleaning decontamination The equipment has been cleaned and decontaminated NAME POSITION HEAD OF DIV DEP INSTITUTE COMPANY SIGNED DATE PLEASE RETURN THIS FORM TO BIOMETRA GMBH OR YOUR LOCAL BIOMETRA DISTRIBUTOR TOGETHER WITH THE EQUIPMENT PLEASE ATTACH THIS CERTIFICATE OUTSIDE THE PACKAGING INSTRUMENTS WITHOUT THIS CERTIFICATE ATTACHED WILL BE RETURNED TO SENDER 14 General Information for Decontamination Please contact your responsible health amp safety officer for details Use of radioactive substances Please contact your responsible person for details Use of geneti
4. biometra a part of Analytik Jena sR ThermoShaker Order No 051 600 230 V Order No 051 690 115 V May 2009 Warning Please read these instructions carefully before using this apparatus Biometra biomedizinische Analytik GmbH Service Department Rudolf Wissell Str 30 Rudolf Wissell Str 14 16 D 37079 G ttingen D 37079 G ttingen Germany Germany Phone 49 0 5 51 50 68 6 0 Phone 49 0 5 51 50 88 1 10 or 12 Fax 49 0 5 51 50 68 6 66 Fax 49 0 5 51 50 88 1 11 e mail info biometra de e mail service biometra de internet http www biometra de 1 Contents 1 CONTENTS ad LIED I 1 2 ae Bus ta ee na pe Ber aan an a ae aa 2 3 DELIVERY i LESE EET 4 4 AGCCGESSORIES z 3 4 ere 4 5 GENERAL INFORMATION 6 6 INSTALL LA T lO N ee 6 61 UNPACK AND CHECK 6 5 2 6 6 3 CHANGING BLOCK MODULES 222 en 7 7 OPERATION OF TS1 8 71 PARAMETER SETTING 5 ciue
5. cally change organism or parts of those Please contact your responsible person for details 15 12 Note for Disposal of Electric Electronic Waste This symbol the crossed out wheelie bin means that this product should be brought to the return systems and or separate systems available to end users according to yours country regulations when this product has reached the end of its lifetime For details please contact your local distributor This symbol applies only to the countries within the EEA EEA European Economics Area comprising all EU members plus Norway Iceland and Liechtenstein 16 13 Notices 14 EC Declaration of Conformity EU Konformitatserklarung March 2009 im Sinne der EG Richtlinie uber elektrische Betriebsmittel zur Verwendung innerhalb bestimmter Spannungsgrenzen 73 23 EWG following the EC directive about electrical equipment for use within certain limits of voltage 73 23 EEC und and im Sinne der EG Richtlinie fur die elektromagnetische Vertraglichkeit 89 336 EWG following the EC directive about the electromagnetic compatibility 89 336 EEC Hiermit erkl ren wir dass folgender Thermoschuttler Herewith we declare that the following Thermoshaker Typ type ThermoShaker TSC Best Nr Order No 051 600 230 V 051 690 115 V den grundlegenden Anforderungen der corresponds to the basic requirements of EG Niederspannungsrichtlinie 73 23 EWG und der EC low voltage directiv
6. cement Fig 6 Rubber belt replacement Remove the external power supply unit AC DC adapter supplied with the shaker from the 12 V socket at the rear side of the apparatus Remove 4 fixation screws on the shaker bottom and remove the bottom plate Replace the rubber belt Fig 6 Assemble the unit 11 0 Specifications Speed range 250 1 400 RPM Temperature control range Temperature setting range 15 C below RT to 100 C 4 C to 100 C Temperature setting resolution Stability Stability 2 Temperature uniformity over the platform Ee Temperature accuracy up to 85 C 222 from 85 C heating rate 20 1 5 ml block Average cooling rate 20 x 1 5 block in the range from re C to RT in the range from RT to 18 C below RT Display Digital timer Block capacity Power 5 C min from 25 C to 100 C in 15 min 5 C min from 100 C to 25 C in 14 min 1 8 C min from 25 C to 4 C in 12 min 16 symbols two lines LCD Simultaneously display of set and actual temperature time and speed 1 min 96 hrs 20 x 1 5 ml microtubes 20 x 2 ml microtubes 20 x 0 2 ml 12 x 1 5 ml microtubes 20 x 0 5 ml 12 x 1 5 ml microtubes external power supply Input 100 240VAC 50 60Hz Output DC 12V 4 5 A The TSC ThermoShaker is designed for operation in closed laboratory rooms at ambient temperature from 5 C to 40 C a
7. d have it checked by a competent person It is the user s responsibility to carry out appropriate decontamination if hazardous material is spilt on or inside the equipment Clean the unit only with a damp cloth Do not use chemical cleaning agents Before using any cleaning or decontamination method except those recommended in this manual users should check with the Biometra Service Department that the proposed method will not damage the equipment Disconnect the mains before removing the outer cover Note there are no user serviceable parts inside in the unit Warranty is void if cover has been removed by user 3 Delivery parts The Biometra TSC ThermoShaker Order No 051 600 690 will be delivered with Fig 1 Delivery Parts 1 x ThermoShaker apparatus Fig 1 1 1 x External power supply unit cable Fig 1 2 2 x Spare rubber belt Fig 1 3 1 x Manual Interchangeable block modules Fig 2 have to be ordered separately and will be delivered separately 4 Accessories Interchangeable block modules Order No 051 610 051 611 051 612 051 613 Description Interchangeable block module for TSC 20 x 1 5 ml tubes Fig 2 1 Interchangeable block module for TSC 20 x 2 0 ml tubes Fig 2 2 Interchangeable block module for TSC 20 x 0 2 ml 12 x 1 5 ml tubes Fig 2 3 Interchangeable block module for TSC 20 x 0 5 ml 12 x 1 5 ml tubes Fig 2 4 051 610 051 611 051 612 051 613 F
8. e 73 23 EEC and the EG Richtlinie ber die elektromagnetische Vertr glichkeit 89 336 EWG entsprechen EC directive about the electromagnetic compatibility 89 336 EEC Dr Juergen Otte Quality Manager 18 15 Warranty This laboratory instrument is produced with the highest practical standards of materials workmanship and design The design and manufacture of parts have been conceived with one purpose to produce units which will give satisfactory service Biometra GmbH guarantees this unit to be free from defects in materials or workmanship under normal use or service for 24 month from date of shipment If during this time this unit proves defective in materials or workmanship Biometra GmbH will repair or replace it free of charge if returned to us prepaid This guarantee does not cover damage in transit damage caused by carelessness misuse or neglect or unsatisfactory performance as a result of conditions beyond our control or consequential losses as a result of failure of our product Biometra biomedizinische Analytik GmbH Service Department Rudolf Wissell Str 30 Rudolf Wissell Str 14 16 D 37079 G ttingen D 37079 G ttingen Germany Germany Phone 49 0 5 51 50 68 6 0 Phone 49 0 5 51 50 88 1 10 or 12 Fax 49 0 5 51 50 68 6 66 Fax 49 0 5 51 50 88 1 11 e mail info biometra de e mail service biometra de internet http www biometra de 19
9. e parameters STOP time 000 RPM thermoblock temperature C which automatically starts rising according to the temperature set in the upper line Fig 5 Time h min 2 OK Time C Start Stop Fig 5 Control panel The time of temperature stabilisation depends on the initial temperature but does not exceed 15 20 min if the set temperature is 37 0 C 7 1 Parameter Setting Use the readings in the upper line of the display set point while setting the necessary parameters 7 1 1 Reaction Time TIME With the help of A and V buttons Fig 5 1 set the required working time interval in hours and minutes If the button is pressed for longer time the increment becomes bigger 1 min increments to reach 10 20 30 40 50 or 60 min after this 10 min increments until reaching the full hour and finally 1 hour increments 7 1 2 Shaking Intensity RPM With the help of A and WV buttons Fig 5 2 set the required shaking intensity in revolutions per minute increment 10 RPM If the button is pressed for longer time the increment becomes bigger 10 RPM for the first 10 steps after these 100 RPM increments to reach 1 400 RPM 7 1 3 Reaction Temperature 2 With the help of A and V buttons Fig 5 3 set the necessary temperature increment 0 1 C If the button is pressed for longer time the increment becomes bigger 0 1 C increments to reach 1 C 2 C after this 1 C incremen
10. ig 2 Interchangeable block modules 20 x 1 5 ml tubes 20 x 2 0 ml tubes 20 x 0 2 ml 12 x 1 5 ml tubes 20 x 0 5 ml 12 x 1 5 ml tubes 5 General Information The TSC ThermoShaker is a compact bench top shaking incubator ideal for all applications requiring heating cooling and shaking in microtubes up to 2 0 ml within the temperature range of 15 C below room temperature RT to 100 C The intensive mixing operation and the incubation heating cooling mode can be used either combined or independently from each other i e the device can work as a thermoshaker incubator without shaking mixing or as shaker mixer without temperature control The TSC ThermoShaker is applicable for DNA analysis extraction of proteins polysaccharides lipids and other cell components DNA library creation preparation of samples for electrophoresis etc The TSC ThermoShaker provides Peltier elements for active cooling Variable speed variable temperature micro tube thermoshaker Gentle to vigorous mixing of samples 2 mm shaking orbit Soft start function Even amplitude throughout the shaker platform Timed shaking operation 1 min to 96 hours with buzzer and automatic switch off Set parameters will be saved Low voltage power supply for safe cold room operation 6 Installation 6 1 Unpack and Check Unpack and carefully examine the ThermoShaker Report any damage to BIOMETRA Save all packing material if damage is found Do
11. nd maximum relative humidity 80 for temperatures up to 31 C decreasing linearly to 50 relative humidity at 40 C 12 10 Service Should you problems with this unit please contact our service department or your local Biometra dealer Biometra biomedizinische Analytik GmbH Service Department Rudolf Wissell Stra e 14 16 D 37079 Gottingen Germany Phone 49 0 5 51 50 88 1 10 or 12 Fax 49 0 5 51 50 88 1 11 e mail service biometra de Attention If you would like to send the unit back to us please read the following instructions Instructions for return shipment Return only defective devices Please contact the Technical Service Department at Biometra Phone 49 0 5 51 50 88 1 10 or 12 to get an Return Authorization Number RAN number e Use the original box or a similarly sturdy one Label the outside of the box with CAUTION SENSITIVE INSTRUMENT and the RAN number sticker Deliveries without RAN number cannot be accepted e Please enclose a precise description of the fault which also reveals during which procedures the fault occurred if possible Important Clean all parts of the instrument from residues and of biologically dangerous chemical and radioactive contaminants Please include a written confirmation that the device is free of biologically dangerous and radioactive contaminants in each shipment If the device is contamin
12. not attempt to operate this device if physical damage is present If you would like to send the unit back to us please read the return instructions page 13 6 2 Installation Place the apparatus upon even horizontal non flammable surface away from any flammable material provide optimum ventilation ensure clearance around the apparatus 20 cm on each side Ensure additional clearance from the bottom side and do not place any object below the unit Plug the external power supply unit AC DC adapter supplied with the shaker into the 12 V socket at the rear side of the apparatus 6 3 Changing Block Modules 10 way plug Fig 3 Changing block modules Remove the four knurled screws Fig 3 1 and disconnect the 10 way plug Fig 3 2 Select the new block module Connect the plug Align the block module so that the warning label is facing the front of the unit and secure with the four knurled screws Attention Please handle the block modules carefully do not let them drop Please disconnect and connect the 10 way plug carefully do not damage it 7 Operation of TSC ThermoShaker Connect the power supply unit to the mains Switch on by using the on off switch at the rear side of the TS1 Fig 4 on off switch Fig 4 Rear side of the TSC The upper line of the display settings shows time RPM and temperature set earlier Fig 5 The lower line of the display actuals shows current readings of the sam
13. ts until reaching 10 C 20 C and finally 10 C increments to reach 100 C Notes The set parameters can also be changed during operation The block temperature is maintained independently of the set time and shaking speed 7 1 4 Program Execution After the TS1 ThermoShaker has reached thermal stabilisation when the set and current temperature readings become the same insert tubes into the platform sockets of the interchangeable block module Press the Shaker Start Stop button Fig 5 4 The platform will start rotation and the timer indicator will start counting up the time interval with 1 min precision Note A N If the rotation speed is set to zero pressing Shaker Start Stop button starts the timer but the platform does not move At the end of the program after the set time elapses the platform motion stops and the timer shows the flashing reading STOP accompanied by the repetitive sound signal until the Shaker Start Stop button is pressed If the working time is not set or deleted and the timer indicator the upper line shows 00 00 pressing the Shaker Start Stop button causes the apparatus to operate continuously until the Shaker Start Stop button is pressed again If required there is possibility to restart the timer when it is running Press the Timer Start Stop button once Fig 5 5 to stop the timer Press the Timer Start Stop button again to restart the timer
14. ture operation Use only as specified by the operating instructions or the intrinsic protection may be impaired After transport or storage in humid conditions dry out the unit before connecting it to the supply voltage During drying out the intrinsic protection may be impaired Connect only to a power supply with a voltage corresponding to that on the serial number label at the rear of the unit Do not use other power supply units than recommended by the manufacturer Ensure that the mains switch and isolating device power supply connector are easily accessible during use Before moving disconnect at the power supply socket The unit should be saved from shocks and falling Do not operate the unit outside the laboratory premises The unit must be placed on a level non flammable surface away from flammable materials 2 Do not operate the unit in premises with aggressive explosive chemical mixtures Do not impede the platform motion during operation Use appropriate vessels tubes for temperature required Never fill liquid directly into the blocks always use vessels To reduce the risk of eye injury during high temperature operation use safety goggles or spectacles Do not put any hot blocks on inflammable surfaces Ensure that the operating temperature is less than the maximum operating temperature of your sample material If liquid is spilt inside the unit disconnect it from the power supply an
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