Cliniscan EEG Clinical Decision Support System User Manual
Contents
1. Frequen N Ww oa a o 3 s The density spectral map is provided in two forms The first one is generated for the entirety of the wave signal and found in miniature form between the EEG signal display and the analytical tools The second is accessible via the analytical toolbox on the bottom left side of the full screen display of the EEG visualizer analyzer under DSA With frequency on the y axis and x axis representing time occurrence of frequencies are then mapped to a colormap The result is a graphical representation of the dominance of particular frequencies over others For instance our color spectrum uses red to illustrate high prevalence and blue to illustrate low prevalence At a glance the user has an idea of which frequencies are relatively more present Combo Tab Represents three of the main tools FFT Power Spectrum Coherence and Independent Component Analysis arranged next to each other to facilitate user investigation Coherence Calculations Coherence Maps 00 32 32 000 to 00 32 42 000 Lateral Sf c s8 e15 Sagittal Sensativity 1 0 75 0 5 Frequency C Composite Delta Theta Alpha Beta O Gamma The user can obtain coherence calculation results between electrodes or between electrode pairs based on the section of the EEG signal selected via the Time bar Lateral interhemispheric coherence and sagittal intrahemispheric front to back coherence can be selecte2. 2014 12 03 24 GMT 0500 Eastern Standard Time Starting pre processing e Tue Feb 25 2014 12 03 38 GMT 0500 Eastern Standard Time Pre processing stage complete Time Chunk Analysis Waveform analysis wavelet and chaos dynamics e Tue Feb 25 2014 12 03 38 GMT 0500 Eastern Standard Time Identified 4 chunks for analysis e Tue Feb 25 2014 12 04 06 GMT 0500 Eastern Standard Time Completed channel analysis for time chunk 900 1800 e Tue Feb 25 2014 12 04 08 GMT 0500 Eastern Standard Time Completed channel analysis for time chunk 1800 2700 e Jue Feb 25 2014 12 04 09 GMT 0500 Eastern Standard Time Completed channel analysis for time chunk 0 900 e Tue Feb 25 2014 12 04 10 GMT 0500 Eastern Standard Time Completed channel analysis for time chunk 2700 3600 Diagnosis Generating diagnostic results from processing data e Tue Feb 25 2014 12 04 10 GMT 0500 Eastern Standard Time Performing seizure detection procedure Visualizer Selection The visualizer selection screen allows the user to select a visualizer to view the results of an analysis Several visualizers may apply to a given analysis result so a listing is shown with a description of each visualization Clicking on the appropriate visualization button will take you to the visualizer page picg mto CliniScan Workflow Request 01 15 Investigation Back Details Status Manifest Visualize EEG Visualizer Advanced visualization for EEG recording Provides ICA D
3. Cliniscan EEG Clinical Decision Support System User Manual Cliniscan a Picofemto product is a clinical decision support system for medical metadata including but not restricted to EEG ECG and medical imaging This user manual addresses the Cliniscan EEG Clinical Decision Support System accessible via http cliniscan picofemto com CliniScan Overview and Key Terms Understanding the terms CliniScan uses to refer to various features of the product will assist you in using it successfully The following are the most important such terms e Data Store A data store is a collection of uploaded files A data store can contain multiple file types although the primary supported file type at the moment is EDF In order to analyze files they are first uploaded into a data store e User Group This is a grouping of users Objects in CliniScan are associated with a user group and this association determines whether or not a file or analysis can be seen by other users A user can be in more than one user group e Data Analysis A data analysis is a process that analyzes one or more data files and produces a an output result e Visualization One a series of files has been analyzed it appears in the data analysis listing From here it can be visualized A visualizer is a custom interface that allows the user to explore the results of a data analysis Icons Used Throughout The Site e This icon indicate that clicking on it will provide a dro
4. SA sub band and detailed channel analysis and detection of regions with characteristics indicative of grand mal seizures EEG Visualizer Prototype visualizer demonstrating resizable layout Visualizer leita Visualizer a kAnalysis 0 2 EEG Visualizer Manifestld 0a96b4dd 484e 49b3 b39f 264208addadc BY Googie Pe BD a picg mto CliniScan S 2 3 ai R 2 0 16 000 e cliniscan picofemto com Data Visualizer EEGTimeChunkAr Sorting By Default v Frequency hz Channel Selection FP1 F7_ w F7 T7 v The Cliniscan EEG visualizer in full screen mode allows for eeg analytic data to be displayed with a dashboard feel The screen is arranged in three sections the Time bar the wave display and the analytic toolbox The tools from the analytic toolbox are arranged in preconfigured bundles accessible at the bottom left pane of the screen The first analytic tab is Power showing Fast Fourier Transforms of any two channels simultaneously and decomposition of any channel into frequency subbands The second tab accesses the Density Spectral Map and the third is a combination of FFT Power Spectrum Coherence and Independent Component Analysis Time bar 00 31 40 000 00 32 00 000 00 32 20 000 00 32 40 000 00 33 00 000 00 33 20 000 00 33 40 000 00 34 00 000 00 34 21 The Time bar allows the user to navigate through the EEG data using two linked navigation bars
5. Sri s Data 02 27 2014 06 06 PM Brian A EDF Type 2 Picofemto Admin Users 02 25 2014 07 14 PM Brian G NewFeb14Store 1 Picofemto Admin Users 02 25 2014 04 44 PM Brian G test 26 Picofemto Admin Users 12 16 2013 03 39 PM Brian G Neuro _Demo_1 14 Picofemto Admin Users 11 04 2013 05 30 PM Cxi G dk_test 5 Picofemto Admin Users 11 04 2013 04 59 PM Brian G Store Alpha 495 Picofemto Admin Users 09 30 2013 05 25 PM Brian G Sample Store 60 Picofemto Admin Users 09 30 2013 04 59 PM Brian G Demo Data Store 693 Picofemto Admin Users 09 18 2013 12 54 PM Brian G Sample Data Store 901 Picofemto Admin Users 09 09 2013 01 01 AM Brian G 20130904 620e56b 1 Picofemto Admin Users 09 04 2013 07 53 PM Brian G 20130904 2111b16 1 Picofemto Admin Users 09 04 2013 07 41 PM Brian G 20130904 9c02744 1 Picofemto Admin Users 09 04 2013 07 39 PM Brian G 20130904 043fb26 1 Test Client 001 Admins 09 04 2013 07 16 PM Brad G 20130904 ffbdf4a 1 Picofemto Admin Users 09 04 2013 07 06 PM Brian G 20130904 bc6c683 0 Picofemto Admin Users 09 04 2013 07 04 PM Brian G 20130904 5dfcdc5 0 Test Client 001 Admins 09 04 2013 06 59 PM Brad G 20130904 bc087e3 0 Picofemto Admin Users 09 04 2013 06 59 PM Brian G 20130904 fb944e8 0 Picofemto Admin Users 09 04 2013 06 58 PM Brian G Data Analysis The data analysis menu provides the option to view a listing of complete or in progress data analyses or to initiate a new analysis Data Analysis v of a picg mto CliniScan Sak Current Analyse
6. The top bar represents the entirety of the file while the bar below displays the highlighted region from the top bar in more detail Regions can be selected in the each bar by dragging the light blue brush Any detected incidents that may be indicative of seizures are marked in red The upper slider indicates the range that is displayed in the lowertime bar 00 50 00 000 00 41 40 00 The red region indicates a potentially _ interesting area 00 44 25 000 00 44 30 000 00 44 35 e00 44 28 000 The lower slider indicates the region that will be display in the details area 00 16 40 000 00 25 00 000 00 33 20 000 00 41 40 000 00 50 00 000 00 58 20 000 00 49 30 000 00 49 40 000 00 49 50 000 00 50 00 000 00 50 10 000 00 50 20 000 00 50 30 000 00 49 50 000 00 50 00 000 00 50 10 000 00 50 20 000 reine eaa Pran n 7 ee ee ee R ent atti NAN ST et Hi gt i aN ge ap OO yn nf A egal VEOH GH AA A git AR Sart WANA NS YON AN INA Near ON LV frre F7 T7 ER r E I E E ENA at L E A A LE PE E EE I EE ES N re A aS TPT l ERL E IE T h N Ae E AA S EA E AA D E E i 5 P7 01 t en I A A A A A A m P1 F3 R a npn gener Ne he gt SRD penne ON tees amie PLA LNA cl Vb rice en etn Soll Ng Pad eatin statin ate heparan a aN Legation yatta hy N tN tal bys A f WASL RADA LV SOO lian 7 ol eRe re eat eee ee ee j CP3an MESS ENE TE AEN mca igo Mi
7. a EENE EOE O O E EEE IRA GIR ATR A ER I EES E N E A E E RRA GE RR E E T EEA E N E RE NE ee ce Rp A N E E I 3 01 U l x q EET TR E EE Cy EEE E E E E EIS TE OG g I FP2 F4 madw AASA Al Tae Tel gt a ple AMA on AANA git A Aya aka NN aa abi dA aA A NOI Aa Ph al yp 3A ny F4 C4 mo 1 m N Ar AAAA pt PAAA DOA AANA PIR LNA pl ANARAN PIA AA LOOK rAr VPN na T ana AN ey SNS Nf NN I ry j C4 P4_ p nin pa E E EE LRA EN A PA ORO N LE E OI SIE AAAA ANA INR nen P402 nA n PEIS E TY E E O E I 00 49 50 000 00 50 00 000 00 50 10 000 00 50 20 000 Sering By Defaut y The EEG display is tied to the selection on Time bar It is comprised of channel name EEG waveform display electrode montage sorting and a zoom function Detected incidences characterized by the analytical workflow are highlighted in a red background The first 12 channels are shown and using mouse scroll the user can view the rest channels By dragging the display section left to right the user can view channel data immediately to the left and right of the initial selection The analytical tools tied to the data selection will update automatically Power Tab The Power Tab is found at the bottom left of the visualizer analyzer interface The user can obtain frequency distribution of EEG channel data using Fast Fourier Transform FFT Additionally user can examine known frequency bands using wavelet subbands decomposition Both demonstrate how prevalent certain frequencies are ove
8. d separately or together The sensitivity of the coherence display can be adjusted so as to display coherence values under and above a particular threshold Within a particular user set range of coherence to be displayed a cutoff marker is available to display higher coherence in red and lower coherence in blue During slow left and right scrolling on the time domain the coherence values are not updated until the user clicks on the refresh button on the top right of the coherence calculations box Coherence values are recalculated after any click on Time bar Coherence values can be displayed for a particular subband as well as for all subbands Independent Component Analysis ICA Independent Component Analysis 00 32 32 000 to 00 32 42 000 Component 0 Component 1 Component 2 X gt Component 3 Component 4 Component 5 o EEG signal analysis in Cliniscan allows the user to identify components representative of the source behind the detected signals The system automatically identifies the top 5 most powerful components at a particular frequency and displays the effect of each component on each electrode via a heat map The scale bar on the right indicates the absolute power of the component on each electrode Therefore the heat map acts as a localization tool for the signal source The user can select the frequency of interest by clicking on the frequency power spectrum of all components ICA analysis is refreshed automatically by click
9. ing on the Time bar but not when slow left and right scrolling through the wavedata is initiated 0 5 10 15 20 25 30 35 Frequency Hz
10. p Workflow Type Request Name Status Duration Created At y Actions Billy Bob Branch Plant EEGTimeChunkAnalysis A Complete 169 9 2 28 2014 11 19 44 PM Picofemto Admin Users EEGTimeChunkAnalysis Test Visualization Feb28 Complete 57 0 2 28 2014 10 53 55 PM Sri s Data EEGTimeChunkAnalysis Test Sri Sample Complete 41 3 2 27 2014 10 01 20 PM Sri s Data EEGTimeChunkAnalysis Sri Test 1 Complete 67 7 2 27 2014 7 13 59 PM Picofemto Admin Users EEGTimeChunkAnalysis 01 15 Investigation Complete 58 9 2 25 2014 5 03 18 PM Picofemto Admin Users EEGTimeChunkAnalysis Q 2 Complete 42 0 2 10 2014 6 33 27 PM Picofemto Admin Users EEGTimeChunkAnalysis Q 1 Complete 174 6 2 10 2014 4 39 32 PM Analysis Details The analysis details page shows the basic information about the data analysis including the name the type of analysis and any notes entered when creating the analysis Back Workflow Request 01 15 Investigation Details Status b Manifest Visualize Name Modality 01 15 Investigation None Analysis Status The data analysis status page provides details of the progress of analysis that are currently processing and a log of actions performed during analysis for completed analysis a picge CliniScan Workflow Request 01 15 Investigation Back Details Status b Manifest Visualize Pre Processing Time Chunk Analysis Diagnosis Complete Complete Complete Pre Processing Extraction of data and downsampling e Tue Feb 25
11. p down menu of actions to perform e This icon indicated that clicking on it will allow you to view or edit the target object e This icon indicated that clicking on it will allow you to download the target item e This icon indicated that clicking on it will allow you to launch a visualizer to examine the output of a data analysis Process Overview The standard process for analysing data in the CliniScan system is as follows 1 Upload the source data to a data store 2 Create a new data analysis and select the source data following the instructions provided for the analysis type 3 Wait until processing is finished 4 Find the analysis in the analysis listing and select the appropriate visualizer to view the results Log in You will be provided with a username and password for this beta version You must log in before any actions are performed on the site User Name L Password A Home Screen Rrefox 7 CliniScan cliniscan picofemto com Home ndex apicg CliniScan Welcome to CliniScan CliniScan is a clinical decision support system designed to provide cloud based medical data analysis and visualization Please note CliniScan is currently in a preview beta testing mode and should only be used for research and testing purposes Step 1 Step 2 Step 3 Upload EEG file in the EDF file format to a data store You Run an EEG analysis workflow against the uploaded files Explore the output of the anal
12. r others They are calculated based on the selection of the EEG signal from the Time bar FFT Power Spectrum FFT Power Spectrum 10 15 Frequency hz Channel Selection FP1 F w F7 I7 00 32 73 000 to 00 32 47 000 The FFT Power Spectrum is a graph of Power vs frequency It provides relative and absolute measures of the expression of frequencies inside the EEG signal The user can choose to compare the frequency distribution of any two channels color and the frequency range is up to 30 Hz Wavelet Subband Decomposition 00 32 40 000 00 32 42 000 00 32 44 000 Alpha hula were hon MA nots haii ili AINA Betaliyhijes Servs Pyaar 00 32 40 000 00 32 42 000 00 32 44 000 Ch The wavelet subband decomposition provides the investigator with the tool needed to examine GAM Mao seaeen ptas sate auteurs atmi prata ene eaaa aaa ana en alle ae tt tb eit ita e fap aaa tw nea ota Each is displayed with a different line 00 32 46 000 00 32 48 000 annel Selection FP1 F7 v Mama th e pt ee fe Me we te 00 32 50 000 OR eg aas gg the frequency subbands delta 0 01 Hz 4Hz theta 4 Hz 8 Hz alpha 8 Hz 15 Hz beta 15 Hz 30 Hz and gamma above 30Hz from any selected EEG channel by choosing the particular channel from the channel selector at the bottom of the subband wave display Density Spectral Map Tab Density Spectral Array Channel Selection All Pa gt 3
13. s New Data Analysis Create New Data Analysis Workflow When creating a new analysis you a required to give the analysis a name in order to be able to identify it later In addition you should select the type of analysis you wish to perform and the user group that will be able to view the analysis results Based on the analysis type you will be prompted to select one or more files to be processed Create Workflow Request EEG Analytic Workflow Single File EDF v Another Group v Notes EDF Data File File Key File Name Start Date HE End Date HE Search Data Store Key Size Name Created On Bill s Repository EDF 40 0 MB chb01_06 edf 02 28 2014 11 18 PM Add Bill s Repository EDF 40 0 MB chb01_04_edf 02 26 2014 11 16 PM Add Bill s Repository EDF 40 0 MB chb01_15_edf 02 28 2014 11 18 PM Add Bill s Repository EDF 40 0 MB chb01_03_edf 02 28 2014 11 16 PM Add Sample Store For EDF 40 0 MB chb01_15_edf 02 27 2014 06 06 PM Add Sri lt lt 21 3 4 5 6 7 8 9 gt View a list of Data Analysis When viewing a list of data analysis you can search through all processing or completed data analysis Clicking on the name of the analysis will take you to the detailed status page for the analysis while click on the actions link for an individual analysis will provide you an option of actions to perform Data Analysis Start New Analysis Workflow Data Store Request Start Date End Date Status s All v Search e Grou
14. ytic workflow using our web can maintain multiple data stores to organize your files and based visualization control access to between users Navigation Bar The navigation bar outlines all the actions that can be performed in the CliniScan system that your user has the permission to perform Data Store Data Store List mg New The data store menu provides the option to view a list of existing data stores or to create a new data store Typically new data stores are created to logically separate groups of files or to provide different security levels for certain files as a data store can hold a large number of files When selecting to create a new Data store the following menu appears with options on to name the type of store The user group indicate which users of the site can see this data store and the files contained in it picgemto CliniScan iil New Data Repository Name User Group Another Group Notes When viewing a list of existing data stores click on the data store name or the edit icon on the right to view the details of the data store picgomto CliniScan fii Data Repositories Create New Data Repository Key File Count Group Created At v Created By Bill s Repository Billy Bob Branch Plant 02 28 2014 10 44 PM Bill G Repsoitory B 0 Billy Bob Branch Plant 02 28 2014 10 41 PM Billy Bob G Repository A 0 Billy Bob Research 02 28 2014 10 41 PM Billy Bob G Sample Store For Sri 5
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