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WinEEG User Manual - Bio-Medical Instruments, Inc.

1. THMT 20 12 2006 26 06 1971 2 fIBEC 19 08706 2007 15 12 1987 T1 Sk 2 19 14 05 2007 07 06 1987 2 HMT 2170372007 14 09 1988 2 20 12 2006 18 08 1382 32M Hi HT Mn 20 12 2006 27 10 1974 ID Date 03 05 2007 Time 10 02 06 Investigation Patient 2 Espot Patient ID 22024 Add Diagnosis Delete Date of birth 02 03 1989 Backup Address Restore Report File 20000127 Backuped Size 2927292 Number of recards 127 Selected 1 Record search condition filter Undefined Each database consists of an investigation list file and data files Records in the investigation list file include patient card data file name and service information A record in the database corresponds to a single data file Data files can be placed either in a working directory folder on the hard disk or in archives on removable drives The working directory for data files also can be placed on removable drives of high capacity such as magneto optical diskettes Data 15 searched over the investigation list file which signific
2. o E ista ds mon Ee oor oto a EN 167 23 Export wavelet bandpower coherence dialog eee ee nennen nane EE senes annees sensns 170 24 EPO EEG uu ossis edit pt dosis nase ewer new ests ee e pr etu VN M 171 2I APO VIGCO 172 20 PEXDOFLEEG SPECTO ALOE A 174 27 ENPO FEG Indices o o vasi d tut ii mE M HER I I ON MEE 176 26 Export EEG independent components parameters 176 20 Video ile COMPTES STON QIOlOD eligunt SIME MU D IM M PU I cU P De dL 176 SUM 179 RUE 31077 00121721 3 E E 180 SUE eas OR 180 O 181 List didlo E uq ERI EN tas tube tp et Desa 182 39 D pdate task list from slave aae 182 50 Checkin Impedance UR Se 183 37 Calibra on ORB VIDETAR Ci OG PR 183 184 S cee a
3. 130 131 Analysis Coherence Cross correlations for Channels commanmntd cesses 130 132 Analysis Average Coherence BRE REI OA II be TU I EE VIN INE EU Ee HU UM SUE E EUIS 151 133 Analysts Phase Spectra Com malls t Hb E ce eoe UII Aaa 151 192 Analysis BISDeciT tee p RR ce I MUERE II MIN SEI SHE 151 1995 ANGIVSIS 1 command osi SE DREW RU Acte I BEN HI DS TUN EN DIS RN SE EIE S EUN CU USED 151 TSO ANGI SIS AVETA SE SPECI COMMANA a boots dulce a 151 137 Analysts Specta Dynamics command eret vetat blu e ae Sees vla bovis oO va ta a NS 151 138 Analysis Parameters of interaction diagrams 151 199 ANGI SIS Jnsent tables TUOT POT btc a end 151 140 Pop up Menu of Spectra Window Add Map command 132 TAT Groups COMMA Nd ctii std iat te ib utate ta t ae 132 TAD A natuss Channels Mund toda Denies 132 TAS ANALYSIS 132 Analysts Group S I ime Mapp E CONUNGNG iiis ans PU ABA ess DETUR OU 132 Jd OTN AICO eden s ERR ean uu eU Via iode OM ERU I M ina
4. 89 De Input C OTOL 91 SCIRET TT m 92 Cm 93 2 Prnt Control 94 Os TWIT CVS DOL RP MH cT 94 Fe IN GIVES atra 95 o Maps Bar WIRGOWJ ate Lai UT US REUS 95 VEN BIO Es WAL OW P Dm 96 T0 Maps BONI cem pde Ru eT near 97 PB DN oar a 97 TD 98 Ud E 98 ID MB VideO W TI OWN T 99 MENU COMMANDS 3 ics Gas cp C 100 PATE OD Rm TTC 100 EOM iecit sien tito E md ing aeri Ceuta iue SS EUR uade 100 View Menr COMIN at ite nga Luo E EA aicut is 101 Po gu AT IRURE m G ms 101 E e EUR Edd 101 Analysts Meni COMMONGS EGE 102 CUD Menu COMMING E a 105 Winrdow mMenu TUB EIU DETUR Mb Rc Mut 105
5. TASER 105 DESCRIPTION OF MENU COMMANDS 106 FeFe NW CONANA AEE r TE EO EE 106 Zoe Data DASE COMMNGNG T E T 107 3 File Open Another Database gt EEG Spectra 107 4 File Open Another Database gt EEG Cross correlations 4 sese enhn eene nnne esses nnn 107 5 File Open Another Database EEG Indices command eese sese 107 6 File Open Another Database gt ERP EP File command 107 7 File Open Another Database gt ERD File 108 File Open Another Database gt ERCoh File commando tei er aa ette o Wad RR AA 108 9 File Open Another Database gt Biofeedback File command 108 10 OPTA Csi x QT LoT 106 14 Import EDPs Data on suse tid 106 I2 Joe POr P Comuna dcus cake mdi 106 dL eC 108 TAT UE COO ie tis verdure Lap tee 109 TOU TOES OVC As COMMI e t
6. te rest heu tuni eui Fori s ad t hau velie 263 IO OAV OO rc 264 PL 265 TIO Graphics Pase Formar 265 assai estu 265 T12 Run Td COD SII 266 113 F mal Report Template List dialo 267 114 Final Reporti emplate r 268 1493 Setup Final Generator dialog esce m 266 116 sett 269 117 Egquipment Confienration dialog ei Sis creates to ea EE 2 1 APPENDIX 1 FINAL REPORT GENERATION SE UD seo Ue 273 PROGRAMMING LANGUAGE FOR AUTOMATIC FINAL REPORT GENERATION SYSTEM 273 VP OA THE PEERS 273 veles aes a et 273 SE EAI OUG TTD ENTE 274 Z Example ol a Hierarchical Menu Propramizcooasee o ee ae ei ente eie ut E m de Mea MERO E NS 276 SOIT OMS esce OTS MEI IM M M IY M e
7. EN 90 Find nearest user label beyond left border of plot window Find nearest user label beyond the right border of the plot window View or edit patient card Decrease sensitivity vertical scale Increase sensitivity vertical scale Decrease speed horizontal scale Increase speed horizontal scale Modify montage Click arrow to open montage list Turn band pass filter on or off Click arrow to open filter list Open or activate final report window for the active program file Open map window Calculate EEG indices Calculate EEG spectra Correct electro oculogram EOG Correct EEG artifacts or restore last correction Mark EEG artifacts automatically Computes event related potentials Computes event related EEG desynchronization Computes event related EEG coherence Computes event related wavelet EEG bandpower Computes event related wavelet EEG coherence Insert patient card into final report text Insert a final report template Cascade windows Tile windows horizontally Tile windows vertically Get context sensitive help on a WinEEG control 91 2 Input Control Toolbar This toolbar is usually placed in the top of the WinEEG window under the main toolbar but can positioned differently and 15 used to control EEG acquisition and to scroll EEG window To show or to hide the Input Control toolbar use View Toolbar Input Control Toolbar
8. 91 Database Parameters Databases of Processing Results dialog Database Of EEG Spectra Database Pathname Enter full path for EEG spectra database or press button to the right of the name field to browse folders Database Of EEG Spectra Working Folder Enter full path for EEG spectra working folder or press button to the right of the name field to browse drives and to select a folder Database Of EEG Indices Database Pathname Enter full path for EEG indices database or press button to the right of the name field to browse folders Database Of EEG Indices Working Folder Enter full path for EEG indices working folder or press button to the right of the name field to browse drives and to select a folder Database Of Evoked Potentials ERP Database Pathname Enter full path for ERP database or press button to the right of the name field to browse folders Database Of Evoked Potentials ERP Working Folder 247 Enter full path for ERP working folder or button to the right of the name field to browse drives and to select a folder Database parameters X Databases of raw data Databases of processing results Browser settings Database records search parameters Database of EEG spectra Database pathname E Working folder Ic SFrajects sw InEE GV IdeasRHelease sS PELA id Database of EEG Indecis Database pathn
9. Files of type EEG files L ancel 27 Look In 164 Choose a folder on a drive or in a network where the file to open can be found 18 File Save As dialog Specifies the name and location of the file you want to save File Name Save ini E Eeg EN I 01 69 M 1 AS eeg I 012 69 eeg 03 69 3 5 I 04 69 MM 04 405 eeg 05 69 E A 5 Beg I 9 File name 7 59 eeg 08 69 Dba eeg 09 69 09 65 eeq 10 69 10 44 11 69 11 655 12 eeg 13 69 13 44 eeg 14 59 14 4 eeg 15 65 eeq 15 40 16 44 eeg 17 65 eeq eeg 18 16 4 les 9 19 69 19 44 20 59 20 A eeg 21 B8 eeg 21 60 22 59 Save Save type EEG files L ancel Type new file name extension will be suggested application The following extensions are used EEG for EEG files RTF for final reports SPC for EEG power spectra IDX for EEG indices ERP for event related potentials BFB for biofeedback files ERD for event related EEG de synchronization ERC for event re
10. aed tte auf de iiis 124 100 Analysis Detection s COMMAND asc cot lbi pes tut 124 TO T Analtysis s pIKeAVerapinmo commana usse oie Get etd ouo e UR Eb deti clas dotum Td po Ev ages 125 T02 Analysts Remove asi ie D t ete ened teu sa eM oe TN oce toD 125 LOS Analysis MIGHT OCIS COMMON Gd s e thes Na 125 T04 Analysis Arnfacts correction COmmaldl di e ei eat tu de Ne ala eA 125 105 Analysis Artifacts correction using templates 4 126 106 Analysis Turn on off band pass filter not in a 126 207 natysiss Compute ERP x COMMING eu cepit tmu ON I d eis 126 209 ANGIVSIS COMPUTE EID eode tr E ERE Ta um UI IN Cus 126 109 Anatysis Compute ERC Ok COMMANA setti EO E REESE austen 127 110 Analysis Compute COMIMONG TD ue DR COR LU 127 TT Analysis Compute Wavelet sern ir rS ba ae STD E IPM SO DP 126 112 Analysis Independent component spectra command esee hne esses enean ntes essen rennes esses nennen 126 113 Analysis Independent component spectra command nnne sss nnns 126 TI4 Analysis Compartsom Of TESSU COMMANA oaa Sae n
11. Auto Select Margins millimeters Lett 20mm Right 20mm Top 20mm 20mm Cancel Printer Portrait Landscape Paper Select appropriate paper Size and Source Orientation Select page orientation Portrait or Landscape Margins 181 Set margin size in millimeters Printer Use the Printer command to choose a printer and to set its options 33 Print Setup dialog The following options allow you to select the destination printer and its connection Print Setup 442108 297 mm Printer Select the printer you want to use Properties Set additional printer options Paper Select appropriate paper Size and Source Orientation Select page orientation Portrait or Landscape 182 34 Stimuli Presentation Program List dialog Use this dialog to choose a stimuli presentation protocol program for stimuli presentation in ERP investigations or to modify the list of stimuli presentation programs After a program 15 chosen EEG acquisition starts with simultaneous stimuli presentation on an additional computer ERPs can be calculated for this EEG file during further processing To learn more about ERP see Event Related Potentials section Stimuli presentation program list Cancel Heread Update BE recording Press the Update button to read a new stimuli presentation program list from a floppy if it was recorded b
12. Gamma Toul 3 AvW 9 00 1 23 901 0 93 5 40 0 56 6 23 0 69 15 31 1 66 5 43 0 89 69 83 11 22 238 o 6 000 20 00 Delta Teta 0 00 Alfa 0 000 uy uv 20 00 Betaz i Gamma 0 000 uy Average values of normalized spectra Normalization frequency band 0 0 64 0 Hz Dm Tea _ 23 36 222 26 93 2 13 16 73 1 24 4 07 0 32 3 84 0 34 3 AVW Cz AvW C4 AvW 4 AvW 5 AvW P3 AvW Pz AvW P4 AvW 6 AvW OI AvW O2 AvW 24 02 2 13 22 47 1 80 17 54 1 45 5 47 0 43 3 71 0 41 23 44 1 84 21 06 1 54 18 07 1 46 3 75 0 32 2 90 0 20 2 07 0 18 3 26 0 27 23 67 1 80 21 06 1 56 20 23 1 59 10 23 11 61 Betal Gamma 1 06 1 35 1 96 0 27 3 91 0 31 1 09 0 11 4 38 0 58 4 42 0 81 7 93 0 64 1 09 0 12 0 36 0 04 1 08 0 10 6 09 0 48 1 19 0 17 0 71 0 09 0 38 0 05 0 62 0 07 141 0 18 1 21 0 13 0 74 0 10 7 000 0 000 uy 239 40 00 30 00 D Delta 0 00 Teta 25 4 0 00 pa Alta ot 20 00 Betaz Average frequency Hz mma C3 AvW 2 48 0 06 5 45 0 07 9 55 0 09 16 45 0 12 23 74 0 13 34 02 0 16 6 07 0 23 Average asymmetry for power spectra 90 mea Af mea Gams CA AvW C3 AvW 0 74 643 5 61 531 3 35 4 67 3 21 4 70 2 63 3 55 1 55 4 00 1 57 3 25 10 75 1125 21
13. 7 F amp Ref 0 3 053 2 30 5010 1 0 00 44 8 T3Ref 0 3 L53Hz 30 0 000 s 9 0 3 053 2 30 5000 2 0 00 44 10 CeRef 03 1053 2 30 0 00 11 C4 Ref QuV s 0 3 D53Hz 30 50 01 Hz 0 00 12 T4 Aef 0 3 D53Hzg 30 50 0 1 0 00 13 T amp RHef Ouwa 0 3 053 2 30 50 0 1 0 00 uv 14 P2Hef 0 3 D53Hzg 30 50 01 Hz 0 00 uv 15 0 3 L53Hzg 30 50 0 1 0 00 uv 16 P4Ref 0 3 053 2 30 50 0 1 0 00 17 03 053 2 30 50 0 1 0 00 uv 18 01 Ref 0 3 053 2 30 50 D 1 Hz 0 00 uv 19 2 Ref 0 3 053 2 30 50 0 1 0 00 20 ECG Duv s 0 3 0 53 30 5000 2 0 00 uv Montage name 5 Montage Parameters View dialog Use the Colors tab of the Montage Parameters dialog to monitor the parameters set You can also choose a montage from the montage list see Setup Montage List command Montage Name This field initially contains the name of default montage from the montage list Use down arrow button to select a different montage from the list to use as a new default You can also rename the selected montage The paper speed horizontal scale can be selected from the Speed list 60 30 15 7 5 3 75 or 1 875 mm sec The left window
14. QN OO gP 0 33 p 0 164 0 66 p 0 002 0 19 p 0 058 0 28 p lt 0 532 0 67 p 0 031 0 17 p 0 742 9 70 p 0 118 a 5 Ne A C P O E UY Y ON U gP Uv Q2 gP A Se Ne c p Te P O QN P C O 5 p m ON OO P go QN OO ON gt gP ON ON a UA Ue 5 lt C NO ON LR 5 Oo NO Oo 2 ON ON 2 O QN ON 0 23 p 0 007 0 20 p 0 002 0 16 p 0 017 0 06 p 0 848 0 30 p 0 000 0 89 p 0 293 0 61 p 0 002 0 74 p 0 488 0 03 lt 0 782 0 39 p 0 276 0 12 p 0 684 0 32 lt 0 773 1 58 p 0 002 0 34 p 0 363 6 56 lt 0 115 0 20 p 0 116 0 48 p 0 002 0 62 p 0 172 0 28 p 0 573 0 39 p 0 390 0 01 p 0 984 2 70 p 0 000 0 21 p 0 454 0 41 p 0 002 0 90 p 0 019 0 12 p 0 744 0 90 p 0 301 0 11 p 0 769 2 14 p 0 270 0 15 p 0 488 0 21 lt 0 083 0 27 p 0 024 0 18 p 0 855 0 07 lt 0 859 2 72 p 0 008 0 34 p 0 358 0 17 lt 0 621 0 57 p 0 002 0 20 p 0 721 0 72 p 0 362 0 54 lt 0 248 0 97 p 0 546 0 44 p 0 120 0 34 p 0 284 0 64 p 0 002 0 44 p lt 0 026 1 65 p 0 000 0 98 p 0 174 0 75 p 0 671
15. 166 Annotation content the beginning of corresponding annotation 4 Type type of annotation that used for data interpretation 5 Trial info additional information for definition parameters of imported trials sweeps Type and Trial info can be changed using Change attributes of time events button After pressing this button Event attributes dialog will appear on the screen Hypnogramm file name field is used to attach additional information to EEG file Use Browse button on the right of the file name field to select a drive and a folder Not implemented now 20 Channel attributes dialog Channel attributes x M ame EEG E Theta 72 This dialog includes following fields Name Name of channel for destination file up to 7 characters Type Type of channel for destination file It can be following EEG EEG channel BIO additional not EEG channel or REF referent Theta and Phi spherical coordinates of sensors placed on the head for EEG channels only 21 Event attributes dialog Event attributes x Beginning of tial Baseline time interval ms 200 Duration m 100 Poststinulus tine interval ma 200 Use digits only Cancel This dialog includes following fields Type type of event for its interpretation It can be following 1 Fragment the beginning of fragments 2 User mark the user label with text 167 3 Artif
16. 169 Here TR X are time readouts Ch X channels Gr X trial groups and D data If Groups In Line option is unchecked ERP data will be written as follows 1 2 Ch TRIG D D D TR2G1 D D D TRNGI D D IRIG2 D D D IR2G2 D D D _ TRNG2 D D TRIGK D D D TR2GK D D TRNGK D D D Add Column Names Check this option to add column names in the first row of the file Column names can be useful for example for data exported to the Statistica program Add Row Names Check this option to add row names in the first column of the file Row names can be useful for example for data exported to the Statistica program File Enter full file path Use button on the right of the file name field to select a drive and a folder Append To the End Of File Check this option to append data to an existing file otherwise the file will be rewritten File appending may be useful for arranging data of several investigations in an entire table for further statistical analysis 170 23 Export wavelet bandpower coherence dialog Export wavelet bandpower coherence E Data Channels amp waveforms Performance data Time Interval From Stimulus z2 From 200 ms 400 step 200 Frequency band Hz From E To fiz Baseline correction To lett tram
17. 17 Wait for end of driver s installation Setup Drivers Completing the Mitsar Drivers Setup Wizard Setup has Finished installing Mitsar Drivers on your computer Click Finish to exit Setup 18 Press Finish to complete Mitsar hardware drivers installation 18 Setup program will begin Guardant dongle driver installation TOM Guardant Drivers 5 12 57 Setup Welcome to the Guardant Drivers Setup Wizard Select whether you want to reinstall or remove Guardant Drivers Reinstall Guardant Drivers C Remove Guardant Drivers Cancel 19 Press Finish to continue installation i Guardant Drivers 5 12 57 Setup Installing uardant Drivers 3uardant Drivers 15 being installed Please wall 20 Wait for finish of driver installation 19 Setup Complete Setup has finished installing WinEEG on your computer Setup can launch the Read and Choose the options vau want below Click Finish to complete Setup 21 Press Finish to complete Mitsar software installation 22 Insert the Guardant dongle in free USB connector 23 Windows will detect a new hardware 24 Select Automatic search for the corresponding driver and allow Windows to install it press button NEXT 25 Sometimes you will need to reboot computer After finishing of Setup you need to run WinEEG program It will ask for automatically se
18. Time 12 34 59 Investigation 2 Patient ID 63534 18 08 1982 Patient name Diagnosis Date of birth Address Mate 20000117 Backuped Size 3019604 Number of records 127 Selected 11 Record search condition filter Undefined E L ancel Export Delete Backup Lomponents Find 155 ICA button calls function computing independent components of average ERPs if ERP database 15 opened independent components of average ERD if ERD database is opened and EEG independent components average spectra if EEG database is opened The Parameters of independent component analysis ICA dialog or Parameters of ICA spectra calculation for selected group of observations appears after calling this function Components button calls the function performing transformation of ERPs to ERP components The results of processing will store to the same database as additional ERP files WinEEG ask for text file contains the description of list of spatial filters The example of such file 15 presented below 1 1 vO 1 1 1 vTL VCPT2ref cmx PINI VCPT3ref cmx N1P2 aC p h VCPTAref cmx v comTL a
19. 191 48 Change signal polarity dialog This function is useful if there is a priori reliable information then some signals were recorded incorrect for example due to incorrect installation of electrodes of their connection to amplifiers Change signal polarity X Attention Incarrect usage of this Function can result to mistakes in signal polarity measurements Use this function if you are absolutely sure that palatity of angal are incorrect due to electrode connection errors Select all Unselect all Cancel Select channel list in which the polarity should be inverted and press OK Attention Please be very attentive using this function Incorrect inversion of signal polarity can lead to mistakes in processing results and their interpretation 192 50 Open dialog trial list Specifies the name and location of the file you want to open 73 LINIVER 000 Events file ANN Trial duration 1 000 Baseline duration ma 300 Trial beginning shift 0 Following additional information is necessary Trial duration ms total duration of trials Baseline duration ms the duration of prestimulus time interval Trial beginning shift ms the duration shift if any shift exists between event and real beginning of trial 51 Font dialog Define font p
20. 0 O The results of EEG power spectral analysis can be presented in seven window modes that are selected by commands available on the Analysis menu Graphs Power spectra auto and cross correlation are shown as graphs for each separate channel For the Spectral Dynamics display mode spectra for each epoch are superposed with a small vertical shift Histograms Total signal power for given EEG frequency bands is depicted as a histogram for each separate channel Disabled for auto and cross correlation Table For EEG power spectra absolute or related percent of spectral power and the frequency of signal maximum for given EEG frequency bands are listed in the table For EEG coherence average coherence and the frequency of signal maximum for given EEG frequency bands are listed in the table For EEG autocorrelations minimal lag value in which autocorrelation function cross zero and corresponding to lag frequency are listed in the table For EEG cross correlations value of first maximum minimum of cross correlation function and corresponding lag are listed in the table Maps Total signal power for given EEG frequency bands is shown on maps For the Spectral Dynamics mode power is mapped separately for each epoch Disabled for auto and cross correlation Asymmetry Total signal power asymmetry for given EEG frequency bands is shown on 75 maps For Spectral Dynamics mode asymmetry is mapped separately for each epoch Disabled f
21. 200 Include interval after ms 200 Clear previous set of artifact intervals D x 1002 Cancel Clear all Load from database Channels Select channels which signals will be used for processing Voltage Threshold Condition Check this button if you would like to use voltage criteria and select appropriate threshold Level Slow Waves Check this button if you would like to use slow wave amplitude criteria and select appropriate threshold Amplitude and frequency band Frequency from to Fast Waves Check this button if you would like to use fast wave amplitude criteria and select appropriate threshold Amplitude and frequency band Frequency from to Clear previous set of artifacts intervals Check this button if you would like to restore all previously marked time intervals Clear all Press this button if you would like to restore all previously marked time intervals 207 Load from database Press this button to define default parameters used in normative database OK Press this button to start processing of data using specified parameters 62 Spatial Filter Parameters Estimation dialogue Spatial filEer parameters estimation i Haw EEG Corrected EEG Fecluded artefacts EEG compoments Topagrafies 4 gt Method Current iteration Save topographies PCA EUER Speed s Invert filter Restore The raw unfiltered EEG wavefor
22. FRC EXE ACSII file name resource file name gt I Basic Terms Basic terms used in the programming language A Menu is a basic automatic final report resource unit A menu is a list of wordings united into an entire group and showed in a window simultaneously A menu can have an additional attribute so called menu header This is an arbitrary text shown in the top of automatic final report generation window when the corresponding menu 15 displayed Menu description contains a list of options An option contains a wording to be shown and selected in the window text to be inserted into final report on selecting the option and a set of commands organizing menu display sequence menus described in the system must be organized in menu blocks A menu block 15 set of separate menu descriptions enclosed in block endblock brackets In simplest cases menu description file has only one menu block The block term is introduced into the syntax in order to lessen description text size It 15 very favorable to organize menus with wordings used more than once into blocks It seems also reasonable to unit logically closed pieces of a hierarchical menu system into blocks 2 Hierarchical Menu System Cycle To understand hierarchical menu system programming principles better let us study a hierarchical menu system cycle First of all just after a hierarchical menu system is called the first block in order is loaded to memory Then
23. enia derse ride bua is sim s 116 View Decrease Speed COMMANG E EE EE 116 OS View Increase Speed COMMOANG siii tt oa ELO sis inna Seta IO Etro Lob La Seco totos UC M a ee ee 116 09 Views sSelectMONBIISe COMI utile tn 116 TONG CODO cS EEI ETUR EIE UN NEMORE TUM tI IRE NR ESO aa 119 AL oEomigt Paraerapiboommalld ss easet 119 72 Recording EEG Monitoring Command t REVENUE EE EN YER ERR ENVASE Sae E I NEUE E Eee aes Raat 119 73 Recording EEG Recording on off eese a rrr nnne nennen 119 Tieke ordne E 119 Re COFOIBg Pon 120 76 Recording Turn Off Calibration 4 120 VACO TECOTUIN E COMMON REDE 120 DC PMter command tin qnentt 120 ARecordino s Photostunulanonm Command 120 OU RECOTdING Photostunulation Program command quiescere d gi vete teu VET ESI YR ae 121 51 Recording Stimuli Presentation Program command eie cata eee vi Ed tA UA vede e I EE RRA pe eee Ne 121 SPAM TZ HO E OFF VISIO COMMGNG 121 Rec orano 7 RETE 121 G4 deecordino Impedance COMMU euer eile Seah cath
24. list instead of entering parameters all over again Shortcut Main toolbar 70 Format Font command Modify font for selected text in final report Font dialog is displayed after calling this command 71 Format Paragraph command Formats selected paragraph s in the final report The Paragraph dialog is displayed after calling this command 72 Recording EEG Monitoring command Use this command to start EEG monitoring that means acquiring EEG to the computer memory and monitoring it in the new EEG window without recording EEG to hard disk The command 15 available only if a new EEG window is opened see File New command To start recording EEG to hard disk use the Recording EEG Recording command Use Filters bar to modify paper speed montage sensitivity and bandwidth To stop EEG acquisition run Recording Stop command Shortcut Input Control toolbar 73 Recording EEG Recording on off command Use this command to start recording EEG fragment to hard disk The command 15 available only if a new EEG window is opened see File New command To stop recording the fragment and to resume EEG monitoring mode run this command once more Use Filters bar to modify paper speed montage gain and bandwidth To stop EEG recording run Recording Stop command Shortcuts Input Control toolbar Keys Enter F2 F3 F4 F5 F6 F7 F8 F9 74 Recording Pause command Pause EEG ac
25. AGG IM 113 LJU Deere oisin 114 e 114 Trl COMMUNA usc Nuvi be est a E 114 41 Edit Adjust trial synchronization x command e sive do cop o eds e dae CORE VOU OR ME ENS NN due URP A UR AE UNDE 114 42 Change 114 29 TrOPEISI s OW sii re ER e od d 114 44 View Toolbar Toolbar command ie x OR UR E Ee uen uc e iri Iu Bs Has tinea I 115 45 View Toolbar gt Input Control Toolbar 115 46 View Toolbar gt Analysis Ioolb rcomnmatid us ios RENE ERI Ip HIE RP E EU 115 47 View Toolbar gt Maps Window commana sueco to pio o oe ku beo peer ep M DU UP I M LM Delon up 115 46 View Toolbar gt Dipole Window command n eye RN DIEA RU Iu 115 40 Views Toolbar lt Filters Bar Command dicente a io C SIS EU e au ee EV eni Df MU Ee t ER 115 50 View Toolbar Maps Bar aao M DU UNE 115 JJ Toolbar Spectra Bar commands usos er I e Diese oq VM a 115 32 Views Toolbar gt Bar
26. Baseline correction Specify parameters for baseline correction To left from Define stimulus before time interval will be chosen for estimation of baseline average potential Length Define length if time interval used for estimation of baseline average potential Attention These parameters are not used in this version of program Frequency band Specify frequency band for which average power or coherence will be calculated 76 Parameters of ICA Spectra calculation for selected group of observations dialog Parameters of ICA Spectra calculation for selected group of observations Channels Time interval for processing Fragment 33r 12 55 39 First word delimiter None Whole EEG file Beginning interval length s 1 0 i Epoch lentgh Overlaping Time window T4 v T4 v TES TE AG C 1 second seconds am Square Pay P3 v 2 seconds t 32 seconds t Bartlett 4 seconde 64 seconds Fa Hanning TB TE A seconds Welch O1 Ay O1 Ay Upper spectra frequency Hz 54 Load Gave Add Debe EN EE Add all Delete Minimal number of averaged epochs i 100 Current iteration Total processing time Cancel Channels Select the channels which signals you wish to process Use Add Delete Select All and Deselect buttons 224 Time Interval Define EEG interval to be processed Fragment Process
27. E Be fee E cree P Speed 30 mms Gain 100 LM Baseline 0 00 Low Cut 0 3 0 53 Hz High Cut Hz 3t HAS 1480 1 48 48 403 Fay F 3 5 vw Fz A v Fast vu FEA TIAA RLAR ARRA Ke C 3 5 MAU wed Ao AN od OON A 2 5 EEUN Td I Po Avy ZEN TBA ERE REM ELGAn Tin m ET PL cece Lg pma vor Ur 1 87 m i lt En m For Help press F1 L 35 3 uly R 35 3 T R L 0 000 5 R L 0 4 71 27 Scalp potentials maps Scalp potentials maps are displaying automatically in Maps window for selected by vertical markers time samples 50 0 nv 50 0 ny 28 Dipole source localization The dipole source localization is performed automatically for selected by vertical markers time samples The results of dipole source localization are displayed in Dipole window QEA RRE 0 069 ECC 1 00000 RRE 0 118 ECC 0 23795 Copy Parameters 12 2 Final Report Window The WinEEG Final Report window is similar to WordPad but with some WordPad features disabled See WordPad Help to learn more about text editing by means of Edit menu commands and Format menu commands The major differences are as follows BE 02 69 rtf Patient Dmitriev Dmitry Birth date 1975 Sex Investigation 6 9 Date 11 02 2001 Time 17 33 28 First WinEEG allows the final report file to be create
28. Fw TEA Paty Dd Fold Teh Peta hw Pz 1 0248vw P4 AvWw 02 AAV Fo zw Fp2 w Fold TEA T a hw DA TES zw DZA TE AvW Fp2 Avw FFA Fp2 Aw Fab Add Foe Fp2 vw Fata Delete Coherence levels Coherence differencies levels Crosecorrelation levels Iv First level Iv First level 0 05 v First level v Second level v Second level 0 1 _ Second level 0 8 Third level Third level 0 05 Third level gm W Fourth level W Fourth level Fourth level Channel pairs of file list of existing channel pairs Select channel pairs that will be added into one of tree channel pairs list First list Second list and Third list Three independent lists of channel pairs Not used pairs and Selected pairs radio buttons defines using mode if each channel pairs list Add buttons Press this button to add selected in left list pairs into corresponding list of pairs Delete button Press this button to delete selected pairs from corresponding list of pairs Three sets of buttons and fields Coherence levels Coherence differences levels and Cross correlation levels helps to define thresholds curves style and curves colors using by interaction diagrams display
29. Photo stimulation Programs EEG Bandranges Stimuli Presentation Programs Graph Formats Title Final Report Final Report Templates Video recording Equipment Parameters Window menu commands Sets modifies Database pathnames Sets EEG display parameters Sets map display parameters Edits list of montages Edits list of fragment names Edits list of user labels Edits list of photo stimulation programs Modifies standard EEG frequency bands Views and modifies the list of stimuli presentation programs for ERP acquisition Modifies formats for displaying ERP graphs Edits organization title Customizes final report generator Edits list of final report templates Select video capturing device Set and modifies parameters of capturing resolution frame rate signal format and on line compression Customizes hardware configuration The Window menu offers the following commands Cascade Tile Horizontally Tile Vertically Arrange Icons Split Help menu commands Arranges windows in cascade Tiles windows horizontally Tiles windows vertically Arranges icons of minimized windows Splits active window in two panes Activates window you choose The Help menu offers the following commands About WinEEG Displays program information and copyright 106 Description of Menu Commands I File New command Run this command to create a new EEG file It should be c
30. lt Duration 2 Durz ms 20 lt lt lt o Duration Dun ms 20 z Dura Duration ms 20 lt lt DurB Amplitude uv z Amplitude B amp mpB uv 30 lt AmpbB Amplitude 2 amp mpz uv 50 lt Ampe Slope 1 511 ums 1 zz 5 Slope 2 512 uv lt ole Sharpness d 2 4T 2 V ms z 02 Dipole and spatial parameters v Use dipole parameters M Use relative resudal energy RRE 0 2 Use dipole eccentrisity ECC x ETT EE lt 0 9999 Use SYD before dipole estimation Epoch duration SWO 200 Wee relative fraction of total energy of first component 03 Use spikeness of component SIAN Eve blink parameters Remove eve blinks Dipole locattion coordinates gt 0 5 Dipole lacattien 2 coordinates lt o Dipole eccentrisity ECC gt 0 9999 Polarity Positive Wave form duration ms gt 180 Cancel Source data for detection algorithm fields define what kind of data will be used for searching of spike like waves using amplitude temporal parameters of waves The source data can be Raw EEG or independent components of multi channel EEG signal ICA components In last case the additional parameter Minimal duration of epoch will be used to divide whole EEG file on separated epochs Amplitude temporal parameters fields define limit
31. Databases Of Raw Data dialog 245 91 Database Parameters Databases of Processing Results dialog eese 246 92 Database Parameters Browser caste Ue ESSEN PLACES ERU Cantona CUTS DIETS 246 95 Database Parameters Base Record Search Parameters dialog esses eene nnns 246 92 Choose Folderealog ssuecstoscde CU uisa AAG ADAG P IM NI CUT II 250 goo kelerences s JE EO ANP QU QUO ei evel a vo SEE UE RU 251 90 rences RE 252 Prelerencesoscale dialogus ena URN cue sang TERN 254 Preferences 255 aso ne 256 TOO Oro 257 IOF Mappuiv parameters 237 LOZ Names OF Froements dialog 258 HOS User Label DESPON AIG OC ie c 259 104 PhotostimillatonW PrOPFAIIE LEISE eu sese ped 260 T03 Bandan eS TlO 261 100 Parameters Of Bandpass Folter didlo pode qeu me e equ UE Od ES PM MU EE 262 TO
32. Define output file name Add to existing file Check this option to append data to an existing file otherwise the file will be rewritten File appending may be useful for arranging data of several investigations in an entire table for further statistical analysis 87 Processing results comparison dialog Processing results comparison l x E EEG Spectra E EEG Spectra Battaglia Gianna 17 03 2003 Battaglia Gianna 17 03 2003 Schindler Michael 17 04 2003 chindler Michael 17 04 2003 Cancel Load Database Select spectra ERP or ERP from the left and right list for comparison Press button Load Database to load a list of processing results included in normative database Press button OK to compute the differences between spectra ERP or ERD and open corresponding Spectra ERP or ERD window 88 Insert tables of spectra parameters dialog 237 Insert tables of spectra parameters E Topograms of power spectra Normalized power spectra Topograme of normalized power spectra Average frequency A amp symmetry of power spectra Topograms of asymmetry of power spectra Cancel Select type of tables and maps while you would like to insert into MS Word The result of this function is placed below Name Schindler Michael Date of observation 17 04 2003 Total epoch number 76 Time interval duration 181 472 s Average power of spectra uV 2 pe Teu A
33. It is recommended that you close all other applications before continuing Click Next to continue or Cancel to exit Setup 13 Press Next button to continue installation Setup Mitsar Drivers Check the equipment that are going to install Drivers the selected equipment will be installed on your computer jw EEG 201 EEG 202 Rheograph Pulse Hou Jammer BFE Phone lt Back Cancel 14 Select required hardware drivers that you are going to install in dependence on your hardware configuration and press Next button 16 Setup Mitsar Drivers Connect USE cable Connect USB cable to the selected and cancel Mew Device Found Wizard that will appear after connection 15 Connect USB cable s to the selected device s and cancel New Device Found Wizard the will appear after connection s Press Next button Setup Mitsar Drivers Attention Salbwoare metalai Fress Next and accept Debe em retal has aod eed unsigned drivers installation by Pornos pressing Continue anyway in metalation of Bis the appeared window Cancel 16 Press Next and accept unsigned drivers installation by pressing Continue anyway in appeared window s 17 y Installing Please wait while Setup installs Mitsar Drivers on your computer Finishing installation
34. Lock Num Lock and Scroll Lock keys To learn more see Status Bar 61 View Channel Names Bar command Run this command to show or hide Channel Names bar where a channel in the active EEG window may be selected for additional actions To learn more see Channel Names Bar 62 View Main Video Window command Run this command to show or hide Main Video window which presents main video camera data for active EEG file Shortcuts Main Toolbar 63 View Additional Video Window command Run this command to show or hide Additional Video window which presents additional video camera data for active EEG file Shortcuts Main Toolbar 64 View Video Window size command Run this command to change a size of Video window which presents video data for active EEG file Shortcuts Main Toolbar EAM 65 View Decrease Gain command Run this command to decrease gain vertical EEG scale Shortcuts Main Toolbar Keys Numpad Minus 118 66 View Increase Gain command Run this command to increase gain vertical EEG scale Shortcuts Main Toolbar Keys Numpad Plus 67 View Decrease Speed command Run this command to decrease speed horizontal EEG scale Shortcuts Main Toolbar Keys Numpad Divide 68 View Increase Speed command Run this command to increase speed horizontal EEG scale Shortcuts Main Toolbar Keys Numpad Multiply 69 View Select Montage command Us
35. Some EEG trials intervals can contain artifacts They can be manually excluded from the process of ERP calculation Place cursor on the trial label rectangle containing the trial number and click The rectangle will change its color All the trials labeled by this color will be excluded from further processing Click again to include the trial in the processing 20 Marking artifacts time intervals To mark artifacts time intervals select corresponding time interval by vertical markers and use Edit Cut command A horizontal blue bar displayed the artifacts marking time interval 2 Copying selected time intervals of EEG record and video EEG record to another file To copy a selected time intervals of EEG record and video EEG record to another file use File Export EEG and Video EEG command This function is useful if it is necessary to prepare a number of video EEG examples to write them to CD The WinEEG program will copy automatically video EEG data video EEG viewer ViewEEG program and some additional service data in selected folder It is possible to run this function many times As the results a number of subfolders will be created and the data will be copied in these subfolders Edit View Favorites Tools Help Back Forward Up Search Folders Move Copy Address Go lol x AUTORUN INF ST
36. datafile Add record Correct EOCG by peores sion method Compute EEP Compute ERD save ERD datafile save ERP datafile Add record m ERP m ERD Add record Montage processing 1 High order bandpass filtering mark artifacts Compute ER Coh Save EE Coh datafile Add record in ER Coh Bandpass Compute wavelet bandpower Save wavelet bandpower in file Add record in ERD Define spatial filter using template Compute wavelet coherence Save wavelet coherence in file Add record in ERCoh Spatial filterme artifacts correction Compute EEG IC spectra Save ICA datafile spectra database database database database database database Update processing report EEG batch processing functional diagram Dipole source localization Dipole source localization function uses scalp potentials and electrode 3 D coordinates as input parameters The 3 D coordinates can be set or modified using commands View Select montage or Setup Montage list See chapter Montage Parameters Electrodes dialog Equivalent dipole source coordinates and momentums are computed automatically using this method and are displayed in a special window QEA RRE 0 069 ECC 1 00000 RRE 0 118 ECC 0 23795 Copy Parameters 56 This window can be displayed using View Toolbar gt Dipole window command The four shel
37. eis t RU on las aap 137 FTACMENL QU NA 157 17D Setupc babel List sc COMMMANG aet EU E weiss deal 157 160 Setup Photosnmulation Programs Combnand sae vua oer aac uec uetus eee y uae IUe 137 EEG Dandranpess COMO ee utendi 138 182 Setup Stimuli Presentation Programs 138 LOS OCUP GTODRh FOEWIOTS i ed teases IE 136 PIOS m E 138 ASCH REDOT cs COILING MM 138 LOO Jnal Report Lemplales eer e due 136 TOA SCHIP VIG COT z dash 136 196 peup Parameters ad exu e a eine quiet iota deside n cR 138 199 III o Cascade COMMONG 138 POO Windows Tori onta ll y Command E e Up aded 139 TOL Window COMMA ted d dus obutd Dodco s aba Up aded 139 192 WINDOW AVION Ge ICONS COMMAN
38. 1 2 2 gem ate pz 02 2000 Time 10249 OO Investigation EEG observation Patient Ce Fatient ID Diagnosis Tet Date of birth 25 07 1960 M Address Test 00000000 Mote TestE EEG monitor controlling Internal memory of monitor to recording of signals an internal memory of monitor Total size Mb Maximal recording duration min Free size Mb Maximal recording duration min Monitor batteries state Clear monitor intemal memory Required maximal continious duration of signal recording Disk free space Mb 1222665 Maximal length of 20 channele EEG recording minute 22891 B recording parameters Resolution Pixels 320 Frames per second 25 Maximal length of recording minute 1 381 Montage Name This field initially contains name of the default montage from montage list Use down arrow button to select a different montage from the list for use as a new default You can also rename the selected montage ID EEG record ID 15 an arbitrary alphanumeric sequence of up to 10 characters to simplify searching the database Date The date of EEG acquisition start 1s entered automatically Use DD MM Y Y Y Y date format for successful database search by date 143 Time The time of EEG acquisition start is entered automatically Use HH MM SS time for
39. AND WAVELET COHERENCE ANALYSIS 41 RECORDING AND ANALYSIS OF ERP ERD ERCOH WAVELET POWER AND WAVELET COHERENCE 42 EQUIPMENT PREPARATION FOR PERFORMING ERP STUDIES cccsccceccsccsccsccsscscescesccsccsccscescessessesccsccscescessessescesscuseescenees 42 de preparanon PSYTASK program S d aeter E E e RE aec eet std dues Sue Cisse eae 42 2 Testine the SVNCHTONICAILOI Of COMPILES entes Li mus da 42 CARRYING OUT OF ERPSTUDIES cose etu E Orte tein Cen Seen eoa cb 43 COMPUTING AND ANALYSIS OF ERP 44 ANALYSIS OF EEG INDEPENDENT COMPONENTS AND ERP INDEPENDENT COMPONENTS 45 1 THE SPECTRA OF EEG INDEPENDENT COMPONENTS sscceccecccscosccsccsccecccccceccessesseccecccaccsccesbesssccsaccececsecberbeccecccececcescsenseses 47 2 SINGLE TRIAL INDEPENDENT COMPONENTS ANALYSIS OF ERPS 48 3 THE GRAND AVERAGE SPECTRA OF EEG INDEPENDENT COMPONENTS 49 4 THE GRAND AVERAGE ERPS OF INDEPENDENT COMPONENTS cscccsssccssccscccscccsscesscesccescceusseesccescsesseesceeeceusseusceesseeessens 50 5 THE GRAND AVERAGE AND WAVELET BAND POWER OF INDEPENDENT COMPONENTS 5 VIDEO EEG RECORDING beue oed
40. Artifact processing Synchronisation Subject response processing Level 100 M w eve yp Stimulus Defined Channels Ont EEG stimulus t1 Threshold for channels Button channel Not selected gt Time interval before ms Time interval after m fos Frequency from gt Frequency to gt Shep hoH Wavelet width 5 cycles v W Substract ERP from raw EEG Smoothing 5 l W Use as default Os 100 Define Load This dialog box works similar as described in previous chapter But user should also specify a list of channel pairs to which wavelet coherence should be compute 218 70 Choose Group Differences dialog Define trial group pairs for calculating differential ERPs Choose group differences ERP 2 gt 2 EHP 15 1 lt 3 3 15 1 lt ERP 45 J ERP 4 ERP 1 gt Select all 1 lt ERP 5 5 lt ERP 15 The 15 lt ERP E E lt ERP 15 13 lt gt lt 15 lt ERP 1 lt 85 r riri ri a Cancel Press Select button to choose all group pairs Press Deselect button to deselect all group pairs if there are for example 8 context groups then not more than 24 trial group pairs c
41. Colors dialog setas cette 147 ov Montage Paramelens VEW GIGI E A 148 Montage Parameters Electrodes dialog 149 7 Transformation Matrix for Weighted Average Referent dialog eese nennen nennen nennen 151 ESOS cc tatu A LM EUER 152 9 dat h EEG Process Ne pat iv Hn RE 156 AVCTOGIN gratas essct und 157 Record Sear eh Farom eler Sd dl OR cene etsi mee e aeos dee e ob eoe E 156 TA BACKUP Data code id me Qo Museo n date Ses vas que Pul E mde 159 TUIS CID OS PRECOR TET 160 T4 Delete Dara broma otabasedtdlog ui tin e ud tu OU eaa 160 IX Fe TO Database alo Tr o dotis t eos ud Chiba duo tut Gah seuss haves ih 161 TOs Statistical iem os 162 TT PWC ODEN 163 AS AO P 164 19 nwon O OP 165 DO Bm 166 ape seti i aS 166 22 EXDOFL AlO O
42. Compute Wavelet coherence Independent component spectra Independent component ERP Comparison of results Add Spike Delete Spike Change Channel Copy EEG Copy Spike Copy EEG to Report Copy Spike to Report Average Spectra Spectra Dynamics Graphs Histograms Table Maps Asymmetry Formula Mapping Formula Graphs Interaction diagram Power Spectra Autocorrelations Coherence Cross correlations for Channels Average Coherence Phase Spectra Parameters of interaction diagrams Insert tables into Report Bispectra Bicoherence Add map 103 Computes event related potentials Computes event related EEG de synchronization Computes event related EEG coherence Performs wavelet ERP analysis Compute Wavelet coherence Compute spectra for independent component of EEG and open ICA window Compute ERP for independent component of EEG and open ICA window Compare spectra ERP or ERD For pop up menu of EEG window Add spike label for selected channel and time sample Delete selected spike label Change main channel for selected spike label Copy EEG time interval into clipboard for selected spike Copy spike waveform into clipboard for selected spike Copy EEG time interval into clipboard for selected spike Copy spike waveform into text of final report for selected spike For EEG Spectra and EEG Indices Window Displays average EEG spectra Displays EEG spectra dynamics Shows processing results as
43. None Lenght imsi sp m Format Channels inline Add Delete Select all Unselect all Select all Unselect all Groups in line File O Eu Add row names Append to the end offile v Add column names cael Time samples in file This dialog works similar as described in previous chapter but user should also specify Frequency band for which average power or coherence will be calculated 171 24 Export EEG Data dialog EEG data export 1s used for saving data in a file readable by other applications Export EEG data q X Interval Selection Fragment 06 08 23 C Full EEG file Start time and label of trials Format v ASCII Binary float C EDF European Data Format UDF Universal Data Format EEG files v 2 0 Compression Her DAT Lexicor EEG files Sampling rate 128 ts File E XTMPADDDODE48 TT E 04 100 Cancel Interval Choose an EEG interval to be exported Selection Exports an EEG interval selected by two vertical markers Fragment Exports an EEG fragment chosen from the list Full EEG file Exports the whole EEG Format Choose format for a file to export EEG interval to ASCII Each column in an ASCII file means one channel and each row one time readout Data written to the file 15 reformatted and filtered according to montage parameters it is not raw data Binary In binary format a singl
44. Option insert text5 menu9 go MenlO test of Option insert text4 menu9 quit Option insert texti 10 next Option insert text2 10 break Option insert text3 10 go 11 Option insert text4 10 quit Option insert texti menuli next Option insert text2 menull break Option insert text3 11 go Option insert text4 menull quit string length should not exceed 256 characters Not more than 256 menus can be described Total length of blocks simultaneously loaded to memory should not exceed 64 menus Not more than 128 blocks can be described A menu should not exceed 32 options A menu description including header wording names and texts to be inserted should not exceed 4000 characters
45. Press 7 key to half decrease speed or key to increase the speed twice Use the Gain list to choose vertical scale gain You can also use and keys Press key to half decrease gain key to increase gain twice To change gain only for a selected channel hold Ctrl pressed see Channel Names bar otherwise eain will be changed for all channels that are visible in the montage Use High Cut Hz list to choose EEG band pass high frequency cutoff To change high cutoff only for a selected channel press and hold Ctrl to avoid changing cutoff frequency for all channels that are visible in the montage Use Low Cut Hz list to choose EEG band pass low frequency cutoff To change low frequency cutoff only for a selected channel press and hold Ctrl to avoid changing cutoff frequency for all channels that are visible in the montage Use Notch Hz list to turn notch 50 or 60 Hz filter on or off To change notch only for a selected channel hold Ctrl pressed otherwise notch will be changed for all channels that are visible in the montage Use Baseline field to change baseline To change baseline only for a selected channel hold Ctrl pressed otherwise baseline will be changed for all channels that are visible in the montage 7 Channel Names Bar Fpz Hef nV cm AO nv zem F3 Ref nV cm Fz Hat AO nv zem F4 RHef nV cm AO nv zem 3 nV
46. Shortcut Analysis toolbar 147 Analysis Rasters Time Frequency command Display time frequency time frequency plots for wavelet ERP analysis in an ERP window Shortcut Analysis toolbar E 148 Analysis Channel List command Selects channel list for displaying graphs and maps in the ERP window Select List of Channels dialog is displayed after calling this command 149 Analysis Group Info command Display statistical results of ERP averaging and response reaction analysis Use this command also to edit trial group names Results of Averaging and Subject Response Processing dialog is displayed after calling this command 150 Analysis Export trial parameters command Export parameters of task performance for single trials to ASCII text file The next table is written to text file 1 First column Time offset in milliseconds of the beginning of trial 2 Second column Label of trial If the trial includes artifacts its label 18 equal zero 3 Columns include reaction time measured by first button in according with parameters of subject response processing for each averaging group or zero if this trial does not belong to averaging group 4 Columns include reaction time measured by second button in according with parameters of subject response processing for each averaging group or zero if this trial does not belong to averaging group 5 Columns include number of first button presses during the tr
47. Size field contains size in bytes of the data file if it is placed in the working directory Otherwise this field contains Not found Backed up Field contains Yes if the data file was backed up in the archive and No otherwise Record search condition filter field contains the information about records filter If this field contains word Defined this means the search condition is not clear If this field contains word Undefined this means the search condition 15 clear To the right of the patient card there are control buttons Open button opens the data EEG ERP EEG spectra and etc file corresponding to the record selected in a new window The file can also be opened by double clicking the row in the record list The Record List dialog 1s then closed Note If you open an ERP EEG spectra and etc database and select multiple records then the Average button appears instead of the Open button If you press the Average button ERPs EEG spectra and etc that have been averaged over all selected records will be calculated and then a new ERP window or a new EEG Spectra window will be opened If a raw EEG database 15 opened then on pressing Average button a Batch EEG processing dialog appears allowing the calculation of ERP ERD ERCoh wavelet bandpower and etc for several investigations simultaneously Cancel button closes the Record List dialog without opening any data file Export button calls the function of ERP ER
48. Spectra dialog if used to define a parameter of averaging Check Keep raw spectra button to save individual spectra in resulting file More accurate estimation of spectral parameters their confidences levels and statistical significance of differences can be done using individual spectra For more information see Analysis Insert tables into report command x Keep raw spectra 158 11 Base Record Search Parameters dialog The Base Record Search Parameters dialog 15 used to define a set of criteria for record filtering In other words only records satisfying all of the specified criteria would be displayed in the list and the others would be ignored The search criteria are saved and re used each time the Record List dialog is opened This logic facilitates manipulation of a certain subset of the database records for example only data acquired during last month But it may also cause mistakes and complications when searching data If you find that some records have suddenly disappeared from the base first of all check the search criteria Each edit box in the Base Record Search Parameters dialog defines one search criterion A record satisfies search conditions if it contains all features that have been defined Blank fields are ignored during search Here 15 the list of search criteria that can be defined Database records search parameters X ID Date fram ta Time from to Investigation P
49. Text in angle brackets lt gt must be present but its contents 15 just an example and can be replaced with another text otructure of Menu Block Description block Block Identifier Menu Description 1 gt Menu Description 2 Menu Description 3 Menu Description n 275 endblock lt Block Identifier gt is a character string not exceeding 16 characters not containing punctuation signs dots commas colons etc Any block must have an identifier that will be used to program calls of this block structure of Menu Description menu Menu Identifier gt title Menu Header Text gt Option Description 1 gt Option Description 2 Option Description 3 gt Option Description m end Menu Identifier 1s a character string not exceeding 16 characters not containing punctuation signs dots commas colons etc Any menu must have an identifier that will be used to program calls of this menu Menu Header Text is an arbitrary text not exceeding 60 characters enclosed into double quotation marks Menu header is not mandatory according to the notation convention otructure of Option Description lt Name gt lt Text gt goblock Block Identifier gt lt Transfer where Name is a wording name indicated in the wording list window It is an arbitrary text in double quotation marks not exceeding 50 characters Text 15 the wording text to be inserted into final re
50. a channel in the montage first of all select a row in the table by clicking the left mouse button on that row The row 15 then highlighted by color You can select several or all of the rows To select multiple lines use the mouse holding Ctrl or Shift key pressed To select all lines click any column heading in the table To change channel status visible hidden click the pictogram to the left of the channel or press the Space key The Show and Hide buttons set the same status for all channels simultaneously The active electrode is defined for all selected channels in the montage by pressing the desired button in the Electrode gt EEG Channels group This group includes buttons for EEG and universal Bio channels The passive electrode is defined for all selected channels in the montage by pressing the desired button in the Referent EEG Channels group This group includes buttons for EEG channels and other referent types 146 The for all selected channels can be set by selecting a value from list The low cut for all selected channels can be set by selecting a value from the Low Cut s list The high cut for all selected channels can set by selecting a value from the High Cut list The notch parameters for all selected channels can be set by selecting a value from the Notch Hz list The baseline for all selected channels is changed by pressing arrow buttons to the right of the B
51. allowed slow wave power 2 frequency band to be treated as slow wave Bispectra Check this option to compute bispectra and bicoherence Additional Processing None Calculate only average EEG spectra Spectra Dynamics Calculate spectra dynamics together with average spectra The Averaging parameter is used to define how many successive epochs to average when calculating dynamics Calculate Calculate EEG coherence for each pair of channels together with Coherence average power spectra Calculate Phase Calculate EEG coherence and EEG phase spectra for each pair of Spectra 199 channels together with average power spectra Keep raw spectra Save raw not averaged spectra in resulting file This option allows do more accurate estimation of power spectra parameters their confidence levels and statistical significance of differences during comparison Press Load button to read parameter values from a file Press Save button to save current parameter values to a file Load from database Press this button to load standard parameters of spectra computation compatible with normative database To define correct parameters press button Load from database and select corresponding condition from the list of conditions Parameters of EEG spectra computal Time interval Selection Fragment Eyes Opened 15 36 16 Ful EEG file Epoch X C 1s C os Eves Closed Auditory Bes Mathematical
52. and resume writing EEG signals on the hard disk to save them for future analysis Total record duration is limited only by available disk space A video signal from a camera connected to the computer can be recorded synchronously with EEG The best results will be if analog or digital camera connected to corresponding video capture card 1s used In this case video signal 1s compressed on line that decrease required disk space and increase possible total recording time The night video EEG monitoring can be performed if video camera with infrared illuminant 15 used Video capture can be continuous or can be turned on and turned off manually many times The video EEG can be played back in moving paper emulation mode User interface provides a fast access to any part of EEG and video record Video signal can be recompressed off line Any selected part of video signal can be deleted to decrease total space Any selected part of EEG and corresponding video signal can be copied to another smaller file to prepare the data for writing to CD A free distributed video EEG viewer 15 available It 15 similar to WinEEG programs and includes all functions for visual analysis of video EEG data you need 2 Visual EEG Analysis After finishing EEG acquisition it 15 possible to analyze stored data visually During both data acquisition and visual analysis EEG signals are displayed in plotter like mode Also the visual analysis mode enables manual measurement of sign
53. backed up Data File and the Corresponding Record option is mostly used for deleting test records not real investigation data 15 Add File To Database dialog 2 xl EEG Es EM nase See 5100000020 Raa Ble 81 20000021 4 C0000016 EEs po000022 EEG Bia amp 00000017 5 0000023 5 Aika ENSE 0000018 24 Bina ENSE 0000019 5 0000025 5 00000015 EEG 00000001 EEG 0000000 EEG files eed Iv remane files if possible Iv Copy files to working Database folder 2 WIN 7 v write volume name to Database Verify addition of each file You can select several files to be added Define also if file names should be kept if data files should be copied to working directory if archive name should be recorded in the database and if patient card should be viewed before file adding 162 16 Statistical report dialog Statistical report X Date from to Time from of Investigation ENS Diagnosis Po Age fram in to so Shep ic Divide by gender Cancel The Statistical report dialog 15 used to define set of criteria for record filtering In other words only records satisfying all of the s
54. channels you wish to export ERP for Use Add Delete Select and Deselect buttons Export EEG spectra x Channel Spectra Fol Aw t Raw EEG spectra Fpz Av EEG power for defined bandranges FAV FAV Bi nee F3 Av Fi Ispectra tor defined bandranges Fz Av t for defined bandranges FAV FAV FB8 Av Bandrange list Taw T3Av lemen 34v 34v 2 5 C4 v Cay Paes Maes 4 4 ower IF THAY Amplitude A Pzt Pz As t Percentage P4 P4 Ay T Bethy Coherence and Phase O1 Ay O1 Ay E 2 7 2 r Bandranges in row Add Include row names el Delete el iw Include column names File Te Append to existing file omen Data Defines what data are to be exported in an ASCII file You can export either Raw EEG Spectra or table of EEG Power for Defined Frequency bands Raw EEG spectra Writes raw EEG power spectra to an ASCII file Columns correspond to channels and rows to harmonics The first row presents the first harmonic with frequency depending on analysis epoch length 1 sec Hz 2 sec 0 5 Hz 4 sec 0 25 Hz see Analysis EEG Spectra command The constant component is not written to the file EEG spectral power Writes the table of EEG spectral power parameters to an ASCII for the defined file Columns present channels and each pair of chann
55. cm 3 AD nv zem nV cm 4 AD nv zem 4 nV cm 5 AO nv zem P2 Ret AO nv zem 4 nV cm AO nv zem 1 nV cm 2 AD nv zem Biol 2 nv zem 8 Maps Bar Map Window 50 0 pv 50 0 ny 95 This bar is placed at the left side of the EEG window and is used to select a channel for processing The channel also can be selected by the Up and Down arrow keys Suggestion to compare EEGs recorded from different sites you can move a channel in the vertical direction while viewing Place cursor on a button on the Channel Names bar and drag vertically with left mouse button pressed The curve depicting the selected channel will also move in the vertical direction When the left mouse button is released the curve will automatically return to its original position Select an EEG interval and run View Toolbar Maps command to view two potential or spectral power maps corresponding to each of the vertical mouse cursors Left and Right 9 Dipole Window 96 The dipole source localization and dipole parameters id displayed in this window RRE is relative residual energy and 15 eccentricity Use buttons Copy or Copy parameters to copy this picture or table of dipole parameters into clipboard 10 Maps Spectra and Indices Bars Horma
56. compressors will take a lot of time to process the video data gt p 30 Print dialog The following options allow you to specify how the document should be printed Printer Select active printer and its connection Choose Properties command to modify printer properties Properties Call a dialog to define additional printer options Prnt Ei Printer Mame Brother HL 1230 seres E Properties Default printer Ready Type Brother HL 1230 series Where Comment Print to file Print range Copies Number of copies Pages from 1 to e Selection Print Range Specify the pages you want to print 180 Prints entire document Selection Prints the currently selected text Pages Prints the range of pages you specify in the From and To boxes Copies Specify the number of copies you want to print for the above page range Collate Prints copies in page number order instead of separated multiple copies of each page 31 Printing dialog The Printing dialog box is shown during the time WinEEG 15 sending output to the printer The page number indicates progress of the printing task To abort printing choose Cancel 32 Page Setup dialog You can define the following parameters for the page to be printed Page Setup Ei i 1 mi Ir Pe m mi Ad 210 297 mm
57. depicted and define whether a statistical significance histogram 1s to be shown for the group 266 Parameters of graphics Attention If you are modifying parameters for several graphs simultaneously only newly entered parameter values will be changed For example you can select all graphs in the table and modify their sizes the remaining parameters will be unchanged 112 Running Header dialog Enter for example your organization title to be printed as running header at the top of each page Running head 267 113 Final Report Template List dialog Creates and modifies final report template list Use the New button to add a new final report template to the list Final Report Template dialog will appear Use Delete button to delete the selected final report from the list Use Edit button to edit selected final report Final Report Template dialog will appear Final report template list 208 114 Final Report Template dialog Enter template name in the Name field Enter final report text in the edit box below Name field Fianl report templater Name New Cancel 115 Setup Final Report Generator dialog Setup final report generator X E ditor Internal Like Wordpad MS Word E dit template Resource file 5 cancel Editor Define what editor to use only with MS Word 97 and MS Word 2000 MS Word 95 15 not supported D Attention MS Word can b
58. differences 15 displayed be vertical bar with different height shorter bar means that significant of differences 1s lower then 0 05 p 0 05 middle bar lt 0 01 and longer bar lt 0 001 Use the Channel list to choose a channel to display EEG coherence or phase spectrum for For Graphs and Histograms modes Value Freq tag and p 0 0 fields of the status bar are used to show power level frequency and significance of differences A frequency component may be pointed to on a graph or selected in a histogram by cursor position when holding the left mouse button pressed There 15 a possibility to add one or more maps corresponding to selected frequency of frequency band A frequency component may be pointed to on a graph or selected in a histogram by cursor position when holding the right mouse button pressed When right button will be released a pop up menu will appears on the screen Use Add Map command to add map for selected frequency 78 F3 FA TJA Cav Ceca Cav MKB 0 420 0 280 nian Toa 01 Aw 02 8w 10 0 300 0 000 P 10 01 9 79 72 P 18 31 MKB 0 420 nen 0 140 dd dd MKB 0 426 0 280 0 140 on on 10 20 Tu 20 Use the Setup EEG Bandranges command disabled for auto and cross correlation to modify parameters for standard EEG frequency bands Use the Setup Mapping Style comma
59. e IM A ELE A E C M M M IE DUM MD M 2 7 Main Features The WinEEG software runs on PC personal computer and 15 intended for clinical observation of EEG video EEG and ERP ERD recording for diagnostic of brain diseases WinEEG software for MS Windows XP Vista allows perform an advanced computerized analysis of the EEG on standard personal computer or Notebook including digital filtering montage reformatting spectra and coherence analysis ERP and event related de synchronization analysis topographic maps and etc WinEEG software is designed to work with Mitsar EEG 201 and Mitsar EEG 202 amplifiers WinEEG is designed for IBM PC and MS Windows XP Vista which together define minimal system requirements But the program performance significantly depends on capabilities of the computer Here are recommended computer specifications Minimal to work with EEG or ERP recording and analysis CPU Celeron 850 RAM 128 Mb HDD 20 Gb IDE Video Adapter SVGA 16 Mb AGP accelerator Monitor 17 Floppy drive 3 5 1 44 Mb CD Writer 4x4x 32 Printer HP Laser Jet 1020 OS MS Windows XP Optimal to perform different EEG ERP ERD processing efficiently CPU Pentium III 800 and higher RAM 256 Mb HDD 40 Gb Video Adapter SVGA 32 Mb AGP accelerator Monitor 17 3 5 1 44 Mb CD ROM 40 x CD Writer x4x 32 Printer HP Laser Jet 1020 OS MS Windows XP Professional to perform additional processing
60. generators is linear at the scalp electrodes 1s not satisfied computing of 15 nonlinear procedure So application of ICA for ERD waveforms does not allow analyzes the signals from independent sources The independent components of average ERDs are computed using selected in ERD database array of individual subject or observation ERDs as a source data The parts of ERD waveforms corresponding to specified time intervals are merged to continuous time series and than this data are decomposed to independent components Grand average ERDs are computed separately for each independent component Individual ERD component waveforms grand average ERD components and component topographies are displayed in ICA window and are available for analysis Additional assumption is also suggested that cortical localization of components is similar between subjects so that it is viable to implement the ICA on array of ERDs Following diagram illustrates consequence of processing and analysis steps 52 ICA average ERD analysis functional diagram Select average ERD files time intervals for a number of trial groups Correct Concatenate baseline time intervals for each from different time interval FED files Compute to grand average independent ERDs of components independent components Decompose ERD database records selection ICA window Computing and analysis grand average independent components ERD ICA average wav
61. graph or a histogram when holding the left mouse button pressed Use the Setup EEG Bandranges command to modify parameters for standard EEG frequency bands Use the Setup Mapping Style command to change color scale palette and map appearance Use Edit Copy command to copy graphs or maps visible in the window to the clipboard They can then be pasted into final report text or into any application WinWord Paint and etc window by means of Edit Paste command The table of spectral parameters can be also copied to clipboard as text Use the File Save command to save newly calculated EEG indices in the database 82 6 ERP Window This window is designed to analyze event related potentials ERP event related EEG de synchronization ERD event related EEG coherence ERCoh or to perform wavelet ERP analysis FA 21 69 Nataliya OF E4 Active Groups C 1 6 6 amp 2 6 9 6 3 8 amp NoGo 2 4 3 366 From m NN Duration m To the end Maps From m Step ms 4 Humber 10 Baseline Baseline Stimulus z Length m 200 9 9 0 9 9 9 2 382 ms C2 572 ms li 4 Ld ERP bar is placed on the right side of the window and at the top there is the Averaging group bar ERPs can be presented in five window modes that
62. graphically depicts the electrodes used their position coordinates and the site scheme montage The referent electrodes are also shown 149 Montage parameters Card Channels Referents Colors Electrodes name Weee Speed rims 30 rirc 6 Montage Parameters Electrodes dialog Use the Electrodes tab of the Montage Parameters dialog to list electrodes to be used and their coordinates You can also choose a montage from the montage list see Setup Montage List command Montage Name This field initially contains the name of default montage from the montage list Use down arrow button to select a different montage from the list for use as a new default You can also rename the selected montage Check a channel to include it in the list for acquisition Spherical coordinates of the electrode upon the head top hemisphere are listed to the right of the channel name The coordinate system 15 set as follows X axis goes from the left ear to the right one Y axis from the nape to the forehead Z axis upwards 150 The Theta spherical coordinate must lie in range from to 90 degrees the Phi coordinate from to 360 degrees Montage parameters I X Channels Referents Colors Electrodes Montage name 7 Theta Phi Theta Phi Theta Phi Theta Phi The
63. graphs Shows processing results as histograms by EEG frequency bands Shows processing results as a table of parameters for EEG frequency bands Shows processing results as distribution maps by EEG frequency bands Shows processing results as asymmetry distribution maps by EEG frequency bands Maps spectra indices ratio Displays spectral ratio dynamics in a Spectra window as graphs Displays interaction diagram in a Spectra window For EEG Spectra Displays EEG power spectra or EEG autocorrelations Displays EEG coherence for one of selected channels or EEG cross correlations Displays EEG coherence averaged over all channels Displays phase spectra for one of selected channels Modify parameters of interaction diagrams channel pairs and thresholds Insert tables of EEG spectra parameters into MS Word Display bispectra frequency frequency plot Display bicoherence frequency frequency plot For pop up menu of EEG Spectra window Add map for selected frequency Channels Groups Groups Channels Time Groups Mapping Groups Time Mapping Formatted Page Average Bandpower Rasters Time Frequency Channel List Group Info Export trial parameters Add Map Add Label Copy Parameter Distribution Copy Channel Copy Channel to Report Sources distribution LORETA Dipole source BrainLock Delete Labels Delete Labels and Maps Generate Final Report Insert Patient Card Insert Final Report Template Select groups Sel
64. gray opaque bar with text Horizontal label A horizontal gray opaque rectangle with text Its vertical position is defined by user when creating the label Text Enter label text for a Vertical label or a Horizontal label 26 104 Photostimulation Program List dialog Photostimulation program list x Duration Frequency Color Duration Frequency Color seconds seconds Hz NE Mame Increasing b 35 Hz 3 b Bath a Both E nw 3 0 Bath 3 Both 3 Bath 3 28 Both Number of flashes flash pairs n i Bath Bath Minimal 0 z z Both z a z Both M uu Bath E Both m hd aximal interval fo a 2 Bath e og Bath Time interval between flashes in pair Bath Bath x 3 14 Bath 3 34 Bath 1 Not used Bath Both 2 used Bath Both a used 3 0 Both 0 Both E E Bath E Both 3 0 Bath 0 0 Both awe iY 3 20 Bath 0 0 Bath M Bath Both 7 Not used E Both Both Not used z s d 0 H jo 0 H Both 24 gt Both 0 Both 3 0 Bath 0 0 Both Cancel 4 Photostimul
65. is not available unless text is selected Shortcuts Main Toolbar Keys CTRL X 27 Edit Copy command Copy selected text in the final report or the active window EEG waveforms spectra graphs ERP maps etc to the clipboard Previous clipboard content 15 replaced Shortcuts Main Toolbar Keys CTRL C 28 Edit Paste command Paste the clipboard content to the final report The clipboard may contain text or graphic objects EEG waveforms spectra graphs ERP maps etc Shortcuts Main Toolbar Keys CTRL V 29 Edit Clear command Deletes selected text from the final report or a selected fragment from the EEG record Shortcut Main Toolbar 30 Edit Select All command Select the whole final report text 113 31 Clear All command Clear the whole final report text 32 Edit Clear All Video Data command Clear the whole video data Video Data Deleting dialog is displayed after calling this command 33 Edit Find command Finds evens in EEG record based on threshold criteria Find events dialog is displayed after calling this command Find a text string in the final report The Find dialog is displayed after calling this command Shortcut Main Toolbar 34 Edit Replace command Finds a text string in the final report and replaces that string with another one The Replace dialog is displayed after calling this command 35 Edit Find Selection command Use this command t
66. like independent component analysis ICA or wavelet band power and wavelet coherence analysis CPU Pentium IV 2000 and higher RAM 2 Gb HDD 500 Gb Video Adapter SVGA 64 Mb AGP accelerator Monitor 19 Floppy drive 3 5 1 44 Mb CD ROM 40 x CD Writer 6 4 32 Printer HP Laser Jet 1020 OS MS Windows XP Vista 10 For Video EEG this computer provide synchronously recording of EEG video from one two cameras with on line MPEG4 compression and audio with on line MPEG3 compression during at least 48 hours CPU RAM HDD Video Adapter Sound card Monitor FDD DVD Writer Printer OS Pentium IV 3000 and higher 2 Gb 500 Gb SVGA 64 Mb AGP accelerator Any 19 3 5 1 44 Mb 8 4 32 HP Laser Jet 1020 MS Windows XP Vista and Direct X 9 0 D Attention DirectX 9 0 should be installed 11 WinEEG software Installation To install WinEEG software 1 2 m Insert the CD to the corresponding drive Open folder with name WinEEG or WinEEGCompact or WinEEGMedium or WinEEGSP Run SETUP EXE program Follow the instruction on the screen Setup program will begin WinEEG software installation Welcome to the WinEEG Setup program This program will install WwinEEG on your computer 1 strongly recommended that you exit all Windows programs before running this Setup program Click Cancel ta quit Setup and then close any programs vou have running Chick Next to continue wit
67. of maximally similar to template This parameter helps to exclude the components with small power from the consideration There is a possibility to add manually own unique topographies into list to extend the possibility of this function The list of topographies templates 15 stored in file with name TopEng cfg The example of content of similar file 1s presented below 1 19 Fp1 Ref Fp2 Ref F7 Ref F3 Ref Fz Ref F4 Ref F8 Ref T3 Ref C3 Ref Cz Ref C4 Ref T4 Ref T5 Ref P3 Ref Pz Ref P4 Ref T6 Ref OI Ref O2 Ref 0 9539 0 9312 0 0405 0 0222 0 1812 0 0383 0 0842 0 2245 0 1529 0 1550 0 1611 0 2318 0 1815 0 1404 0 1451 0 1497 0 1733 0 1536 0 1647 0 8 5 1 19 Fpl Av Fp2 Av F7 Av Fz Av F4 Av 8 T3 Av C3 Av Cz Av C4 Av T4 Av T5 Av P3 Av Pz Av P4 Av T6 Av 1 O2 Av 1 0530 0 9975 0 4066 0 0717 0 0979 0 0518 0 0650 0 2405 0 1508 0 1461 0 1481 0 2091 0 2983 0 2314 0 2187 0 2228 0 2684 0 3023 0 3069 0 8 5 Each component template 1s described by four consequent lines 1 First line text name of topographies that will displayed in dialog window 2 Second line list of channel names in dependence on used montage The names include the reference names also to have a possibility to use separate topographies for different referents Third line
68. of processing results Browser settings Database records search parameters ID Date From ta Time from In Po Patient C Patiend ID Diagnosis Date of birth from to E Address P Existed in the working folder Backuped Date From To fields define interval of EEG acquisition dates current year example To enable automatic search by date use DD MM Y Y Y Y date format Time From To fields define the interval of EEG acquisition times before noon for example To enable automatic search by time use HH MM SS time format Investigation field contains a text string to be presented in the corresponding field of the database record see also ID field 250 Patient field contains text string for example patient name to be presented in corresponding field of the database record see also ID field Patient ID field contains a text string to be presented in the corresponding field of the database record see also ID field Diagnosis field contains a text string to be presented in the corresponding field of the database record see also ID field Date of Birth From To fields define the interval for dates of patients birth for example from 01 01 1950 to 31 12 1959 To enable automatic search by date use DD MM Y Y Y Y date format Sex field displays patient
69. of this value is accepted as the threshold Finally raw EEG recordings are not used for processing only those reformatted and filtered according to the user selected parameters established in the active montage Following diagram illustrates consequence of processing and analysis steps EEG indices analysis functional diagram Spatial High order EEG datafile Calibration Montage Bandpass bandage 5 ocessing artifacts Ine calculation processing filtering FIR filtering alcul Indices window Database of observations TN Indices file Database of EEG indices EEG indices processing Therefore EEG indices calculation results depend on the processing parameters set using the EEG Bandranges command or in the Parameters of EEG indices computation dialog and also on the montage parameters While defining limits of the EEG frequency bands should not cause any difficulties selecting parameters for the indices can be quite highly counter intuitive If the threshold is too low could be as low as zero half waves will be selected if there are any fluctuations of the signal Taking into account that real amplifiers have some level of self noise and that there 15 also other noise detected a number of cases such a low selection of the threshold may well lead to detection of high frequency oscillations including some with a frequency exceeding 30 Hz On the other hand if a high thresho
70. output file name Add to existing file Check this option to append data to an existing file otherwise the file will be rewritten File appending may be useful for arranging data of several investigations in an entire table for further statistical analysis The output file consists of four columns 1 First column order number of trial 2 Second order number of averaging group 3 Third average value for selected time interval 4 Fourth Latency of pick in selected time interval absolutely exact for each trial due to a different kind of noise Please check output data attentively and try to determine pick latency manually for incorrect output results D Attention There is no way to determine the pick latency in selected time interval 86 Export of spectrum parameters of independent component dialog Export of spectrum parameters of independent compe X Bandrange list Values Power Amplitude A Percentage X Label File Ez Add to existing file Cancel Specify parameters for export Bandrange list Choose what frequency band list will be used see Setup EEG bandranges command Values 236 Choose what values to export Power P absolute power values Amplitude A square root of absolute power values Percentage frequency band power as a percentage of total power Label Specify label for exporting data File
71. p NoGO a a GO VCPT 5ref cmx v comTR a p NoGO a a GO P4 wmF VCPT 7ref cmx P3b P a a GO VCPT8ref cmx SW H a a GO 9 P3 supF a p NoGO VCPT10ref cmx P4 monCC a p NoGO 11 Each row corresponds to one component First column contains name of component that will be used as name of averaging group in resulting file Second column contains name of averaging group of source ERP file to which the processing will be applied Third column contains name of text file in which the transformation matrix spatial filter revealing the component from multi channel ERP 15 written by command Analysis Save signal filter command 156 9 Batch EEG Processing dialog Montage list allows automatic changing of source EEG file montage Batch EEG processing x Montage 73 Artifacts processing Artifacts correction Parameters EOG rejection Parameters Artifacts rejection Parameters EEG filtering Bandrange list 1 Bandpass filter Nore Data processing f Save EEG file far future processing Event related potentials Event related desynchronization Event related coherence Wavelet bandpower ERD Wavelet coherence EEG spectra and coherence seme ee ICA spectra Create report Process file 04 100 Cancel Check Artifacts correction option
72. passivity off line The next command of WinEEG program help to control corresponding features of Video EEG recording Setup Video Recording View Main Video Window View Additional Video Window View Video Window Size Recording Video Recording Edit Clear Edit Clear Video Data File Compress Video Files File Export EEG and Video EEG Recording Play Forward Recording Rewind Forward Positioning to video pictures corresponding to manually selected EEG sample can be performed using horizontal scroll bar of EEG window The selection of sample in EEG window to which corresponding video frame will be displayed can be done using Sample slider placed at the top of EEG window IST Export and Import the data There is a possibility to save raw EEG data for selected time interval or whole EEG record to anther data format The WinEEG program supports the next data formats for export raw EEG data 1 ASCII data format The columns of resulting data file correspond to montage channels and rows to time samples The data 1s processed before exporting according to the montage parameters band pass filtering and artifacts correction procedures and 15 stored to the file in micro Volts 2 Binary data format The data is stored as 4 bytes float number in multiplexed format 1 e letting J number of montage channels and I number of time points samples in selected time interval the data points are as follows data point 1 for cha
73. reactions will be calculated 2 For each of the trial groups set the ordinal number of the Stimulus relative to which reaction time will be calculated 3 Set the allowed Time Interval for reaction time values milliseconds 4 Define reaction type for Left Right or both buttons One of the following reaction types can be chosen No don t analyze signal from the button Press patient must press the button in response to stimulus presentation Average reaction time number of correct trials and number of errors will be determined during processing A trial is treated as an error if the patient did not press the button or pressed it more than once or pressed it not within the time interval that had been defined Don t Press patient must not press the button in response to stimulus presentation Correct trials and errors false alarms or commissions are counted during processing 5 Choose a Channel for each registered Attention There are different modifications of buttons simple button one level button advanced button two levels button and digital button Setting of button channel depends on what type of button was used level signal should be used for simple button Both Low level and High level signal can be used for advanced button if the subject press both key during investigation The digital inputs Dig1 Dig2 should be used for digital button 6 Choose the agreement concerning mu
74. scale fields group provides these changes By default whole duration of independent components time interval is displayed The Graphs horizontal scale fields group allows set to display only beginning time interval with specified duration 233 83 Correct graphs baseline dialog Correct graphs baseline x Interval for baseline corrector correct default Substract average value for interval from beginning to 100 Cancel By default no baseline correction 1s performed For ICA ERP it is useful to make baseline correction if prestimulus time interval exists This dialog allows specify the duration of baseline time interval 84 Select components for filter dialog Select components for filter Suppressing C Revealing Cumputation method Clearing of component tapagraphies Pseudoinversino of component tapagraphies Cancel Check components using for spatial filter computing Type of filter Specify type of spatial filter that will be computed Suppressing Compute spatial filter that will suppress selected components from raw multi channel EEG or ERP 234 Revealing Compute spatial filter that will reveal selected components from raw multi channel EEG or ERP Computation method Specify method for spatial filter computation Clearing of comp
75. see Kalcher J Pfurtsheller G Discrimination between phase locked and non phase locked event related EEG activity EEG and Clin Neurophysiol 1995 V 94 P 381 and G Pfurtscheller F H Lopes da Silva Event related EEG MEG synchronization and desynchronization basic principles Clinical Neurophysiology 1999 V 110 P 1842 1857 The method of ERCoh is not common at present but it is described for example in Shibata T Shimoyama L Ito T Abla D Iwasa H Koseki K Yamanouchi N Sato T Nakajima Y The synchronization between brain areas under motor inhibition process in humans estimated by event related EEG coherence Neurosci Res 1998 v 31 p 265 271 Event related EEG de synchronization and synchronization ERDS 15 calculated by several steps 1 To reduce the affect of the common referent source EEG 15 reformatted to average weighted referent do not forget to use a montage containing an average weighted referent AvW 2 The signal for a given frequency range 15 detected for each EEG fragment trial by means of digital band pass filters do not forget to turn band pass filter on 3 To reduce the influence of ERP components on ERDS averaged ERPs are computed over the trial to be then subtracted from each trial 4 To assess EEG signal power dynamics for a given frequency range for each time readout bin the values are squared and averaged over all trials 41 5 To reduce data dispersion the EEG power dyn
76. sex M or F Address field contains a text string to be presented in the corresponding field of the database record see also ID field Note field contains a text string to be presented in the corresponding field of the database record see also ID field Check Existed in the working folder option to select only records corresponding to files located in the working folder Attention Using this condition may significantly slow down the database search Check Backed up option to select only records corresponding to EEG files that have been backed up at least once 94 Choose Folder dialog Choose folder Folder name Cancel H c WnEEGEn Release LE Folder Enter folder name or browse the list to find the appropriate folder Drive Choose a drive to look for the necessary folder on 251 95 Preferences EEG Input dialog Set options for new data acquisition in EEG window Amplifiers Displays name of amplifier block the software is designed for I O Port Choose input output port to connect amplifier block to Length of Input Buffer Choose how many seconds will be stored before starting EEG acquisition x EEG input EEG window Scale Signals polarity Printing Length of input buffer 5981038 vw Add labels each time when frequency of photastiulation will be changed Monitoring style during EEG recording Show value for each channel during recording f Movi
77. spectral parameters for standard EEG frequency bands in an EEG indices window or in an EEG spectra window Ratio formula is defined by means of Calculator bar Attention Maps cannot be viewed if the source EEG was reformatted to a bipolar montage before processing Shortcut Analysis toolbar 128 Analysis Formula Graphs command Display dynamics of the ratio of two spectral parameters for standard EEG frequency bands as graphs in EEG spectra window Ratio formula is defined by means of Calculator bar Shortcut Analysis toolbar 129 Analysis Interaction diagram command Display interaction diagrams in an EEG spectra window Shortcut Analysis toolbar 130 Analysis Power Spectra Autocorrelations command Display EEG power spectra or EEG autocorrelations in an EEG spectra window Shortcut Analysis toolbar 131 Analysis Coherence Cross correlations for Channels command Display EEG coherence channels or EEG cross correlations for a selected channel in an EEG spectra window Shortcut Analysis toolbar Py 131 132 Analysis Average Coherence command Display BEG coherence averaged over all channels in an EEG spectra window Shortcut Analysis toolbar 128 133 Analysis Phase Spectra command Display EEG phase spectra for a selected channel in an EEG spectra window Shortcut Analysis toolbar 134 Analysis Bispectra command Display bispectra frequency frequency plot in a
78. stimuli was carried out synchronously with EEG acquisition After calling this command one of the Wavelet Decomposition dialogs is displayed to define additional processing parameters Raw data 15 reformatted according to montage parameters before processing Attention EEG reformatted to a bipolar montage cannot be mapped If you wish to view maps choose a monopolar montage for the active EEG window before calling this command Electrode coordinates are additional parameters for maps see Montage parameters Electrodes dialog Incorrect coordinate settings can disable mapping Shortcut 128 Main toolbar b 111 Analysis Compute Wavelet command Compute wavelet coherence for the active EEG file and opens an ERP window Wavelet coherence can be calculated only if presentation of visual auditory stimuli was carried out synchronously with EEG acquisition After calling this command one of the Wavelet Coherence dialog is displayed to define additional processing parameters Raw data 15 reformatted according to montage parameters before processing maps choose a monopolar montage for the active EEG window before calling this command D Attention EEG reformatted to a bipolar montage cannot be mapped If you wish to view Electrode coordinates are additional parameters for maps see Montage parameters Electrodes dialog Incorrect coordinate settings can disable mapping Shortcut Main toolbar 112 Analysis In
79. the first menu in the block 15 processed necessary information 274 on this menu is read into RAM from the resource file A wording selection window is formed automatically menu header if defined is highlighted and the control goes to the procedure processing operator commands by means of these commands an user can choose one of existing wordings After a wording has been chosen corresponding text is inserted into final report and processing procedure starts In the simplest case when there is no menu block call commands among control transfer commands corresponding to selected wording next menu is processed Control transfer commands can enable transfer to next menu in order or to miss a number of menus described within executed block In a more complicated case one more menu block is called to be executed In this case required block information is loaded to memory and the first menu of new block is processed When processing of newly loaded block menus is finished the control transfer command corresponding to the wording that had been selected and had caused the new menu block loading to memory In other words in this case one more menu block is processed after inserting the selected wording into text and before control transfer to next menu according to the described control transfer command described The system enables nested calls of menu blocks to be processed 1 a block can be called to be processed from another block calle
80. the source one Time Interval Before ms If the parameter value exceeds zero and the interval from the trial beginning the synchronizing stimulus see above exceeds this value resulting trial will be shortened from its start Time Interval After ms If the parameter value exceeds zero and the interval from the trial beginning the synchronizing stimulus see above exceeds this value resulting trial will be shortened from its end Calculate Statistical Significance Check this option to calculate statistical significance of ERP difference from baseline separately for each ERP or differential ERP and for each time read out or for each pair of readouts taken to calculate differential signal The Student criterion 15 used to estimate statistical significance Use as Default Check this option to have the current parameter values saved and then used for next EEG file processing Press Load button to read parameter values from a file Press Save button to save current parameter values to a file Groups of trials Labels Correct Incorrect Aani E EC Mathematical 0 Headin D in ea or dg em mo PB ie 4 3 6 5 Artifact processing Level 1 Channels EEG Thresholds for channels responce processing Defne pression Time interval E ft Ime interea oU er ms Calculate statistical 0 100 Load Save Load from da
81. to another file Interval Choose an EEG interval to be copied Selection Copy an EEG interval selected by two vertical markers Fragment Copy an EEG fragment chosen from the list Full EEG file Copy the whole EEG Output data Choose a type of output EEG data Raw EEG Copy unfiltered raw EEG Filtered EEG Copy filtered EEG Low cut s High cut Hz and Notch Hz fields allow you specify filters parameters for filtered EEG Folder Define a destination folder in which the EEG data and video files will be recorded 173 This function is useful if it is necessary to prepare a number of video EEG examples to write them to CD The WinEEG program will copy automatically video EEG data video EEG viewer ViewEEG program and some additional service data in selected folder It 1s possible to run this function many times As the results a number of subfolders will be created and the data will be copied in these subfolders Edit View Favorites Tools Help ie kj S Back Forward Up Search Folders Move To Copy To START EXE utility helps to open all copied data automatically by ViewEEG program ViewEEG program is the restricted version of WinEEG program providing reviewing of video EEG data D Attention ViewEEG program requires DirectX 9 0 installation 174 26 Export EEG Spectra dialog EEG spectra export is used for saving data in a file readable by other applications Channels Select the
82. to suppress components of EEG related to artifacts Press Parameters button to call up the Artifact correction using standard component topographies as templates dialog and set parameters of processing Check EOG Rejection option to eliminate eye motion artifacts for all files Press Parameters button to call up the EOG Rejection dialog and set parameters for EOG rejection Check Artifacts Rejection option to automatically detect parts of EEG record including artifacts and eliminated them from processing for entire file Press Parameters button to call up the Search and Rejection Artifacts dialog and set parameters for artifacts rejection Use Bandpass List to choose a list of standard EEG frequency bands for automatic source EEG filtering 157 Use Bandpass Filter to choose a standard EEG frequency band filter for automatic source EEG filtering Choosing an option from the Calculate group defines how to process selected files The following processing could be performed 1 Save EEG file for future processing The results of artifact correction EOG rejection artifact rejection and EEG filtering will be saved to EEG file for future processing This option is useful if the goal of processing 1s to calculate different parameters spectra ERP ERD and etc for the same list of files and for the same parameters of preprocessing 2 Event related potentials The event related potentials will be computed and saved automatically to correspon
83. value may be used in several different trial groups For groups with empty label lists ERP would not be calculated On the right side of the table there are fields for displaying statistical results of trial grouping artifact analysis and response processing The Correct fields show number of trials in each eroup when the patient performed the task correctly The Incorrect fields show number of trials when the patient performed the task incorrectly Task performing correctness is controlled by monitoring button states according to Subject Response Processing parameters Number of trials treated as artifact 1s displayed in the Artifact fields Parameters for event related potentials computation X Groups of trials Mame Labels Correct Incorrect Artifact mmm mE RUNE 2 2 NENNEN 3 pem mem EE pu 3 1 2 0 x 0 0 5 E o 7 pum tele a a 5 Group differences E 4 3 5 5 Choose Artifact processing Synchronization Subject responce processing Level 1 00 uM efined Channels mulus 1 Define Threshalds For channels Button channel No Compression ot Time interval before ms 0 Time interval after ms E Calculate statistical significance M Use as default LE 100 Load Save Load fram database Cancel 212 Group Differences This field defines a list of tr
84. vie COM ports using null modem cable to provide synchronization of signals recording and stimuli presentation The additional PSYTASK software developed for Windows XP Vista presents different stimuli of additional PC such as images sounds and text PSYTASK software allows prepare pre defined stimuli presentation protocols and presents these protocols during ERP recording During ERP recording PSYTASK software is working in so called slave modes and WinEEG software controls the PSYTASK s functions by sending the control codes via COM ports WinEEG software receives the amplified pre filtered digitized EEG signals stores them to hard disk of PC for the future processing and control synchronously stimuli presentation process 24 3 The video EEG recording system configuration Computer Aanplifier Mirsa EEG 201 or Mitsm EEG 202 E Mitsar MITSAR EEG 202 Keyboard 7 E Fpi Foz ES o FA o o o X FT F3 Fr 4 Fa WinEEG T E er FC o oO ru o o CPi J P3 Pz Video capture card Sound card s o 1 01 oz 02 o o 0 an NON b Fa 7 inm em F j Od OF OF p go F PF Video In idi i cal Jl sockets Power ca
85. w Synchronization with Vertical Access codes Video Database Cancel The access codes should be entered to corresponding fields Main field is used to open EEG recording function Video field is used to open video signal capture function Database field is used to open functions of comparison the data with normative database Attention The access code is 8 characters string with digits or capital English letters and without additional symbols such as space point comma and others 21 Mitsar EEG System Overview There are at least three system configurations that can be used for practical goals 1 The EEG recording system configuration 2 The ERP recording system configuration 3 The video EEG recording system configuration Any combination of mentioned above system configuration can be used also 1 The EEG recording system configuration Comparer Aunplitver Iitsaa EEG 201 model 106 107 Photosiumulato MITSAH EEG 701 Eevhbnaard OW O FA FBN o T4 o o T o L o2 WinEEG Blouse Hs Photoctimal able Power Power calle T amp USE Patent ed wilting button Power adapter for medical devices Power cable The EEG recording system based on Mitsar EEG amplifiers 22 Computes Amp
86. weights for each electrode in topographies 4 Forth line default values of Similarity and Component number parameters UJ Attention Be very attentive modifying content of TopEng cfg file Incorrect modification of this file can fail this function 210 64 Parameters For Evoked Potential Computation dialog Parameters for evacked potentials computation Time interval Fragment 15 12 18 Ful EEG file with separate processing for each fragment Ful EEG Duration of base line time interval ms 200 Duration of paststimulus interval m 000 Artifacts elimination parameters Threshold 00 Channels Jal Do you want to calculate differences of waveforms Do vou want to calcutate statistical significans of EP 100 Cancel Time Interval Define EEG interval to be processed Selection Process interval between two vertical markers Fragment Process fragment selected from the list Full EEG file with Process the whole file calculating ERPs for each fragment separate processing separately for each fragment Full EEG file Process the whole file Duration Of Base Line Time Interval ms set the duration of interval used for base line estimation Duration of poststimulus interval ms set the duration of the poststimulus interval Artifact elimination parameters set Threshold in uV and choose which Channels to process You can choose on
87. wishes to support the development of new methods for EEG analysis 60 WinEEG COMMANDS AND INTERFACE REFERENCE WinEEG Windows 1 EEG Window 07 Belyakova Ekaterina isual 19 57 07 o x Biol 2 An EEG window is used for electroencephalogram monitoring The Channel Names bar placed left side of EEG window 15 used for channel selection The Slider placed in top of EEG window 15 used to select time sample for which a synchronous video frame is displayed The Status bar placed in the bottom of WinEEG window displays parameters for a selected channel In the top of the EEG window there is a time scale displaying fragment names and time marks Any EEG interval in the EEG window can be selected for further processing by means of two vertical markers 61 ET TOVATEST EEG 17 24 11 NM NM O2 Ret 1 0 usm Some amplifiers have additional digital TTL inputs In this case the signals from these inputs are displayed by red horizontal bars placed at the bottom of EEG window Thin horizontal bar correspond to logical zero high TTL level and thick bar to logical one low TTL level Usually the special digital button is connected to these digital inputs to measure subject reaction Upper horizontal bar correspond to Digital 1 input and to left button lower bar correspond to Digital 2 input and to right button If Mitsar amplifiers h
88. 0 20 p 0 702 0 45 p 0 365 0 13 p 0 790 0 05 lt 0 767 0 89 p 0 255 1 17 p 0 002 1 68 p lt 0 219 0 803 0 39 p 0 245 0 P QN gP e m Uv WS gP P QN Y gP Ne QN gP ON ON ER gP Gamma 0 12 p lt 0 244 0 26 p 0 229 0 44 p 0 000 0 53 p 0 202 0 38 p 0 089 1 34 p 0 240 0 76 lt 0 282 2 25 p 0 370 0 20 p 0 660 0 25 lt 0 421 0 17 p 0 558 0 49 p lt 0 408 0 91 p 0 145 0 42 p 0 244 2 74 p lt 0 082 0 21 p 0 267 0 23 p lt 0 692 0 01 p 0 955 0 48 p 0 014 0 16 p 0 840 0 53 p 0 450 2 09 p 0 313 OI AvW 0 21 p 0 526 0 15 p 0 000 0 96 p 0 000 0 66 p 0 322 0 74 p 0 050 0 07 p lt 0 312 3 61 p 0 064 O2 AvW 0 07 p 0 822 0 39 lt 0 479 1 28 p 0 071 0 04 p 0 622 1 30 p 0 209 0 64 p 0 237 2 58 p 0 140 Comparison of asymmetry of power spectra 90 0 17 p 0 000 0 20 p 0 553 0 66 lt 0 167 0 63 p 0 251 0 92 p lt 0 144 0 22 p lt 0 021 0 46 p lt 0 598 Er pomo powo pawo paio 0 00 an nr 50 00 40 00 Delta 0 00 Teta an Alta 50 00 Betal 40 00 60 00 60 00 Betaz BL UL Gamma 00 245 3 000 3 000 Delta 3 000 Teta 3 000 Alfa 3 000 Betal sp SD 50 3 000 3 000 3 000 3 000 Betaz 3 000 Gamma 3 000 Th
89. 1 defined as the maximum magnitude of the first time derivative during the leading edge of an EEG wave 511 9 Slope 2 defined as the maximum magnitude of the first time derivative during the trailing edge of an EEG wave SI2 10 Sharpness defined as the second time derivative of an EEG wave at its pick d P d t 5 For more information see following papers 1 P Y Ktonas Automated spike and sharp wave SSW detection In Methods of analysis of brain electrical and Magnetic signals EEG handbook revised series Vol 1 2 A S Gevins and A Remond Eds 1987 Elsevier Science Publishers B V 211 241 pp The dipole parameters using by WinEEG program are the following 1 Relative residual energy RRE 2 Dipole source eccentricity ECC X Y 4Z The parameters of dipole source are used both for more exact spike detection and for eye blink artifact rejection Both monopolar and bipolar montages could be used for EEG to which automated spike detection is applied But dipole source parameters will be not estimated for EEG at bipolar montage The estimation of dipole model could be done using raw EEG voltage and EEG component PCA or ICA topographies 1 D Flanagana Agarwala Y H Wanga J Gotman Improvement in the performance of automated spike detection using dipole source features for artefact rejection Clinical Neurophysiology 2003 Vol 114 P 38 49 2 P Van Hese P Boon K Vonck I Lemahieul R Va
90. 185 TOTALS acetals 185 POUT EE a sn 186 187 name oett E 187 EEG 188 LAND IA Of VGC OO 188 E OE E E E ETE 189 47 Adjust trial synchronization using synchro impulse dialog 190 AS CHONCE SIONAL ua eve Ine ve 191 IO OI AOR S PET 192 192 SANE Pora ranha Ol O RE DSL 193 193 Jo Farameters Of senals didlo sicir 195 54 Parameters Of EEG Indices Computation eee eene 196 55 Parameters Of EEG Spectra Computation dialog sessi 197 56 Parameters Of EEG Auto and Cross correlation Computation dialog eese eene eene 200 Nonlinear analysis parameters dialogus Gaeta io ees Poe espe ttu estu 201 IGOKEA CHOU IGLOS osos
91. 2 3 4 Use dipole parameters if this button is checked the dipole source parameters will be used in spike detection algorithm Use relative residual energy fields define a usage and limitation of this parameter Use dipole eccentricity fields define a usage and limitation of this parameter Use SVD before dipole estimation field define will singular value decomposition of multi channel EEG data will be performed before dipole source localization procedure will be applied or not If this button checked the topography of first component will be used as source data for dipole source localization procedure Attention Is the source data are independent components the singular value decomposition is not performed Epoch duration for SVD field defines duration of time interval corresponding to spike wave for which the multi channel EEG data 15 used as source data for singular value decomposition The time interval 1s selected so that the pick of spike places at center of interval Use relative fraction of total energy of first component fields to define a usage and limitation of this parameter Use spikeness of component Smax Smax sum S S N fields define a usage and limitation of this parameter The spikeness 15 computed according following formula Smax Smax sum S S N Where Smax maximal value of signal in the first component sum S S total energy of first component and N number of samples in epoch Eye blin
92. 38 0 Investigation Reading Fatient Hame Hug Flavio Fatient ID Diagnosis 7 Date of birth 21 04 1989 Sex m Address Mate FH Sampling rate Hz 250 Record duration hh mrm 2 00 0 32 Cancel ID EEG record ID 15 an arbitrary sequence up to 10 characters which simplifies searching the database Date The date of EEG acquisition start 15 entered automatically Use DD MM Y Y Y Y date format for successful database search by date Time The date of EEG acquisition start is entered automatically Use HH MM SS time format for successful database search by time Investigation Select investigation type from list 1 EEG observation 2 Biofeedback Patient Enter patient s name Patient ID Enter patient s card number Diagnosis Enter a brief disease diagnosis The final report may contain more detailed description Date of birth Enter the date of patient s birth Use DD MM YYYY date format for successful database search Sex Enter patient s sex M F Address Enter patient s address 187 Note Enter other useful info patient s insurance policy number for example the fields of patient card are not mandatory but can be useful when searching database Remember that all patient info would be automatically added to the final report Sampling rate The sampling rate of EEG digital recording is displayed in this field Record duration The total recording time of whole file is displ
93. 5 Parameters of independent component analysis ICA dialog eese eene eene nnne nnn eese 22 76 Parameters of ICA Spectra calculation for selected group of observations dialog ssec 226 pure uude Eom 228 78 Results Of Averaging And Subject Response Processing dialog 229 79 List of channel pairs and parameters for EEG coherence and EEG cross correlations dialog 230 OO Darametekssor averaeuis OR accused Mi de bl de uid 231 Sl electoveraeutg BOUNDS TOF displaying GIGI bte pea 232 OZ Denne CHAPS SCONE CIAO RR 232 go Correct orap hS Daen e 233 SA SCLECE CONIDONEIIS TOF Uter dialog ties tals 233 COMPONCHL aa 234 86 Export of parameters of independent component dialog 234 86 Export of spectrum parameters of independent component dialog esses eene eene nnns 235 O7 Processmg Tesulls Comparison seni set o c a tton d das pesto NE A UN 236 Insert LADIES of spectra parameters dialog ver OE IR dua CN 236 69 Insert tables of spectra comparison didlQg sie deett se a b a es bla eeu 240 90 Database Parameters
94. 50 0 70 0 100 0 150 0 200 0 300 0 500 0 700 0 mV cm c The Low cut column shows the selected low frequency cutoff value For any channel in the montage you can set one of the following values for low cutoff frequency 0 16 Hz 1 0 sec 0 53 Hz 0 3 sec 1 6 Hz 0 1 sec 5 3 Hz 0 03 sec and 0 0 Hz DC 0 016 Hz 10 0 sec 0 032 Hz 5 0 sec 0 053 Hz 3 0 sec 0 045 Hz 3 5 sec for DC amplifiers d The High cut column shows the selected high frequency cutoff value For any channel in the montage you can set one of the following values for high cutoff frequency 15 Hz 30 Hz 50 Hz 70 Hz and possible 150 Hz 0 5 Hz u 1 5 Hz for different modification of amplifiers filters are 2 d order Butterworth filters e The Notch column shows the notch values For any channel one of the following notch values can be set Turn Off 45 55 Hz 40 60 Hz 35 65 Hz 55 65 Hz 50 70 Hz 45 75 Hz filters are 12 th order Butterworth notch filters Attention Do not use the wide width filters unless absolutely necessary since it can distort bandwidth f The Baseline shows the selected value of the channel baseline offset The offset is set in mV micro Volts its range and step depend on the selected gain for the given channel So minimal baseline offset corresponds to mm on the screen and offset range 15 from 100 mm below to 100 mm above Changing Channel Parameters To modify a parameter for
95. 606 600 ICA window for independent component ERPs The topographies of components are placed on the left side of ICA window The power variance of components is placed below topographies The bitmaps displaying individual not averaged components are place on the right from topographies The average components are displayed by curves places below bitmaps Each row of bitmap corresponds to single trial or individual ERP The first or individual ERP trial is displayed on the bottom of bitmap The x axis corresponds to the time The value of components 1s coded by color The curves display average ERPs for different conditions The legend of curves the correspondence of colors to conditions 15 displayed right The parameters of equivalent dipole source for component topographies are displayed on right side of window Here RRE is Residual Relative Energy allowing estimate the accuracy of fitting of real data by dipole model and ECC 15 eccentricity of dipole The time offset of selected ERP samples 15 displayed on status bar The command Copy component from pop up menu of window is used to place corresponding bitmaps and graphs to clipboard The command Component name from pop up menu of window is used to modify corresponding name 88 The command LORETA for component from pop up menu of window is used to runs LORETA application and automatically store to it the topographies of selected c
96. 63 Analysis Select groups command Select averaging groups from list of groups for displaying of the graphs Parameters of averaging groups dialog is displayed after calling this command 164 Analysis Select group pairs command Select averaging group pair from list of groups for displaying of the difference curve graphs Select group pairs dialog is displayed after calling this command 165 Analysis Change graph scale command Change vertical scale for ICA average curves Define graph scale dialog is displayed after calling this command 166 Analysis Correct baseline command Define time interval for baseline correction Correct graphs baseline dialog is displayed after calling this command 167 Analysis Save components filter command Save to the ASCII file a matrix transforming raw EEG ERP to the components of EEG ERP 168 Analysis Save signal filter command Save to the ASCII file a matrix spatial filter revealing or suppressing signals from raw EEG ERP for selected list of components Select components for filter dialog is displayed after calling this command 169 Analysis Export activation curves spectra command 136 Export activation curves for independent components of ERP or spectra of independent components into ASCII text file 170 Pop up menu of ICA window Copy component command Place bitmaps and graphs to clipboard corresponding to selected component by mouse The result of work of this c
97. 92 0 075 0 033 0 043 0 085 1 000 0 102 0 033 0 041 Pz 0029 0 029 0 034 0042 0044 0042 0034 0041 066 0 086 0 066 P4 0026 0033 0028 0033 0039 0 048 0045 0030 0041 0 063 0 094 0 067 0 039 0 055 0 000 0000 0000 _ Cancel 152 8 Record List dialog WinEEG has its own database to simplify archiving and searching of files containing EEGs and processing results EEG spectra EEG indices etc There is a separate database for each type of file EEG files EEG spectra files EEG indices files and so on It is also possible to create several databases for one file type in order to group data by some criteria by investigation date for example Use the Setup Database Pathnames command to create a new database or to select an existing one Database of EEG recordings x GA Patient JID Date Birthdate 000 0 0 0 4 K L 58 HMT 2571222006 01 SM 59 20 02 2007 24 02 1988 2 16 04 2008 16 10 1989 L1 8M 3705 72007 OF 03 7989 18 05 1387 1 8M 59 MAB 18 15705 2007 13 03 1383 2 13 04 2007 21 11 1988 3 2 HI 18 16 05 2007 30 08 1988
98. 92 37 48 26 60 14 79 P4 AvW P3 Avw_ 10 94 6 39 3 04 6 13 4 36 441 2 57 4 35 4 01 3 73 1 61 3 50 4 32 3 23 6 AvW T5 AvW 11 13 17 88 11 78 2 56 4 52 7 11 4 03 3 75 4 76 1202 240 LODS O2 AvW O1 AvW 346 471 0 81 4 14 8 56 341 3 74 4 20 bo pios 2 61 2 33 3 f Delta E 00 Teta 00 Alta a 00 Betal 40 00 Betaz um Gamma 50 Ut E 50 00 The values of corresponding spectra parameters and their confidence interval are placed in the cells of tables 89 Insert tables of spectra comparison dialog Insert tables of spectra comparison xX Power spectra Topograms of power spetra statistical comparison Normalized power spectra Normalized power spectra topograme Topograme of normalized power spectra statictical comparison Average frequency Asymmetry of spectra power Topograme of asymmetry of power spectra Topograms of asymmetry of power spectra statistical comparison Cancel Select type of tables and maps while you would like to insert into MS Word The result of this function is placed below Name Battaglia Gianna Schindler Michael Date of observation 09 05 2004 Total epoch number 2 76 Comparison power spectra uV 2 P Deu Alfa Bear Beta Gamma Tow _ Fpl AvW 23 89 lt 0 190 5 56 lt 0 319 9 39 lt 0 119 0 80 lt 0 117 4 63
99. A dde ted 139 195 Window OP CODICIS cete eee 139 T94 Window REO EO LITT 139 Help Abont WINE Ga CONGHO uc taa c RE VB CH Reha USA eS HUN CEU EUER 139 D TT ren Tene P 139 DO RONDE 140 199 45126 Commund System INCI scc 140 199 WMOUE COmmana CSN SCI uaa ROS 140 200 Minimize command System MENU issues de Pee ea ERR NN 140 command SYSTE MENU det eee ples eH Pee 140 202 Next command document window System MENU eese eese esent 140 203 Previous command document window System 141 ZU 6 TONO SVSICIE Heu IUe 141 205 tuse vette i tuse 141 c mE 142 1 Montage T aramee Patient Card didlog usate c o NE Het s a eae E NI bue 142 2 UMontape Parometersc C o 143 ParometersodJeterentsalalo0 astuce 146 4
100. ART PAR VIEWEEG EXE E objects 954 My Computer START EXE utility helps to open all copied data automatically by ViewEEG program ViewEEG program is restricted version of WinEEG program providing reviewing of video EEG data A Attention ViewEEG program requires DirectX 9 0 installation 22 Search for EEG events Sometime it is necessary to find quickly such called EEG events WinEEG program is able to finds simplest events time intervals during which the absolute voltage of selected EEG channel is higher the defined threshold To start this procedure use Edit Find command 67 23 Automated spike detection To automatically find and mark spikes use a command Analysis Spike Detection All founded spikes will be marks by vertical dot lines and spike s labels in the bottom of EEG window A name of channel in which the pick voltage was maximal is printed in spike s label WinEEG DO0007473 EEG 10 37 37 n8 x Edit View Format Recording Analysis Setup Window Help x be u mn mSS oj xjmnptUulissS sis jm 9s kE 4 gt BE Speed 30 5 Gain 200 LM Baseline 0 00 u H Reset Low Cut 2 0 3 0 53 Hz High Cut Hz Total number of spikes 58 For Help press F1 L 56 9 uly R 56 9 uly IT R L 0 000 5 R L 2 The EEG window could be divided into two parts by horizontal splitter In thi
101. Clear all pick labels and maps voltage data voltage data For Final Report window Activates final report generation procedure Only Russian version available Inserts patient card into final report text Inserts a final report template into final report text For ICA window Select averaging groups from list of groups for displaying of the graphs Select averaging group pairs from list of groups for displaying of the difference curve graphs Change vertical scale for ICA average curves Define time interval for baseline correction Save to the ASCII file a matrix transforming raw EEG ERP to the components of EEG ERP Save to the ASCII file a matrix spatial filter revealing or suppressing signals from raw EEG ERP for selected list of 105 components Export activation curves Export activation curves or spectra into ASCII text file spectra For pop up menu of ICA Window Place bitmaps and graphs to clipboard corresponding to selected component by mouse Modify component name Runs LORETA application and store to 1 the topography of selected component Save to the ASCII file the parameters of selected component for the future statistical analysis Copy component Component name LORETA for component Export of component parameters Setup Menu Commands The Setup menu offers the following commands Database Pathnames Preferences Mapping Style Montage List Fragment Names Label List
102. Commanga 116 33 Views Toolbar gt ERF Bar command ge Na UH e SE 116 34 Views Toolbar lt gt Bar command so S ei A 116 29 Calculator Bar Commana c uec eae nuces pae cuace modios unes 116 56 View Toolbar gt Averaging Groups Bar command 116 57 View Toolbar gt Customize Main Toolbar command sss eene enses nnne essen sanare ness nan 116 56 View Toolbar gt Customize Input Control Toolbar 116 59 View Toolbar gt Customize Analysis Toolbar command esee sese eene essen nnne essen aane nnn 116 tatus TROT COMING RN MEI MR D IR MEN 117 Gls VIEW Dar COMMONG aes E uve Us Eder SER 117 62 View Main Video WING OW COMIMOANG PR T r E 117 05 View Additonal Video Window command isccasviovasicunssd etaed eod in eer Eee Qe Rave ev 117 VL Views Video WINDOW MTT r 117 03 VIEW Decrease Gain COMING A ARRIERE 117 dncrease QUIT COWBOY
103. D EEG spectra and EEG independent components spectra export It can be useful for exporting processing results of several investigations to one ASCII file for further statistical analysis Find calls automatic record search function A Base Record Search Parameters dialog will then be opened Add button calls the function that adds a data file to the database A file is added to the database in two cases First if it is necessary to add a file to the database that has not yet been recorded This may happen after an investigation if data was saved by Save As command or if the file was copied from other encephalographic hardware Second files are added if there 1s a need to create a new database for example if the old one is lost If Add 154 command is called a File Open dialog appears Using the standard Windows browsing interface find the file of interest and open it If the selected data file has a compatible format EEG 1 5 EEG 3 0 or WinEEG an Open dialog will appear There are two exceptions EEG 1 5 EEG files with bipolar acquisition and EEG 3 0 spectra files cannot be added to respective databases Delete button calls the record and data file deletion function Delete Data From Database dialog is then displayed Backup button calls the function that backs up data files from the working directory to an archive Backup Data To Archive dialog appears then Restore button calls the function of data file copy
104. E Doy EE pedea ael ade eue adeo eo TR OO EO E eU eR HR GE 53 EXPORTANDIMPORT THE DA Xii esee ea cs au Ue E SEES UD Ce ae ETE R Papa 53 GRAND AVERAGING AND BATCH DATA PROCESSING ccccsscccssscccsccccscsccccccccsccccsccccscccccsccccsccccscccccccccscccseess 54 DIPOLE SOURCE LOCALIZATION 55 WINEEG AND LORETA Veto PR 56 AUTOMATED SPIKES DETECTION AND ANALYSIS 56 WARRANTIES i uL Aim Lim UE ADEL a Lis 59 WINEEG COMMANDS AND INTERFACE REFERENCE sssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssosssssssssssssssssssssssso 60 WINEEC WINDOW S MT 60 BELG WIUNGOW 60 2 W DO OW arenas 72 DAP UD O MOPS 73 4 EEG Power Spectra Auto and Cross correlations 74 JELO ndices ITI T 50 NUN MUT 82 ZW E OV A 56 WIDE cen state eaten ato M gg I M dM ea M E 89 DSTI Too C
105. EG amplitude 1 difference between maximal and minimal values in the selected interval A 0 1 uV Average signal frequency 1 0 Hz 7 Photo stimulation frequency FS 5 Hz d 11 Montage modification To edit montage parameters run the View Select Montage command 12 Changing speed horizontal scaling On the Filters bar choose an appropriate value from the Speed list You can also use and keys Press key to decrease speed by half or key to double speed 13 Changing gain vertical scaling On the Filters bar choose an appropriate value from the Gain list You can also use keys Press key to half reduce gain by half or key to double the gain 65 To change gain only for a selected channel hold Ctrl pressed Otherwise gain will be changed for all channels that are visible in the montage 14 Changing upper cutoff frequency On the Filters bar choose an appropriate value from the High Cut Hz list To change high cut only for a selected channel hold Ctrl pressed Otherwise high cut will be changed for all channels that are visible in the montage 15 Changing lower cutoff frequency On the Filters bar choose an appropriate value from the Low Cut Hz list To change low cut only for a selected channel hold Ctrl pressed Otherwise low cut will be changed for all channels that are visible in the montage 16 Setting AC Mains 50 60 Hz no
106. ERP corresponding to standard and deviant stimuli in whole task In this case we need to define at least six averaging groups see Parameters for Event Related Potential Computation for which the ERP will be computed separately This definition can be done as shown below Standard1 1 Deviant1 2 Standard2 3 Deviant2 4 Standard 1 Deviant 2 3 4 The computation of differences of waveforms is very useful for ERP analysis To do this averaging Group of differences should be defined The three useful groups of differences can be defined for 45 mentioned above example Deviant Standardl Deviant2 Standard2 and Deviant Standard In this case the processing parameters will be the next 2 1 4 3 6 5 The artifacts elimination procedure bases on comparison absolute voltage of EEG with defined threshold The recommended value of voltage threshold is in voltage interval from 70 to 100 uV Attention Select Only EEG mode for artifact detection if the micro switch signal was recorded Otherwise all sweeps including subject response will be eliminated Usually the synchronization by first stimulus is recommended Another setting of synchronization parameters can be used if two or more stimuli in the trials are presented with different intra stimuli interval The parameters of subject response processing should be defined if signal of micro switch was recorded only Finally WinEEG have a number of predefined sets o
107. Meses ome ns 202 29 A Vernaced spikescalculation dl gione a eher gus e adu ua dE 204 OU FOC RECHOU uli ee aep Poux vade ra Deu qi 205 OT Seurch amd rele con 206 02 Filter Parameters ESMA On eoe vod t E aue 207 63 Artifact correction using standard component topographies as templates dialogue esses 206 64 Parameters For Evoked Potential Computation dialog 210 65 Parameters for Event Related Potential Computation dialog eese eene eene 211 67 Parameters For Event Related Coherence Computation dialogue eese eene nennen 215 05 Wayelet DecompDosSuOn GIG mc eto ditus a teas 216 GOWN CICEC idu Reo 217 70 Choose Group Differences dialog ce t v Hr ME Ha t aua aii t uim 216 71 Artifact Rejection Thresholds dialog ccccccccccsssesssccccccccncnesseeceeeeeecaenssseeeeeeeeaaenseeeeeeeeaaauaseeeceeeeaaaaaseeseeeeaaaaaaseseeeesauages 219 72 Subject Response Processing Parameters dialog eese essen 219 73 Parameters of ICA spectra calculation dialog cesses 224 d Parameters OF ERF oe 220 7
108. Reading Artefact YCPT Slo Addition C Nor C Spe f Cale Cale Kee Cancel Load Save Load from database a 100 200 56 Parameters Of EEG Auto and Cross correlation Computation dialog 2 Parameters of EEG auto and crosscorrelation computation x Time interval Selection e Fragment 15 06 25 Full EEG file Channels EEG only Epoch lentgh 1 second C 4 seconds 16 seconds C 64 seconds seconds f seconds 32 seconds Artetacts elimination Polinomial trends 2 Slow waves Power of signal 200 Bandrange 0 5 1 25 100 pe Load GAVE Cancel Time Interval Define EEG interval to be processed Selection Process interval between two vertical markers Fragment Process fragment selected from the list Full EEG file Process the whole file Channels Define a sunset of channels to be processed Epoch Length Select epoch length for analysis Maximal lag 15 half of epoch length second Maximal lag 512 ms 2 seconds Maximal lag 1024 ms 4 seconds Maximal lag 2048 ms 8 seconds Maximal lag 4096 ms 16 seconds Maximal lag 8192 ms 32 seconds Maximal lag 16384 ms 64 Maximal lag 32768 ms Artifact elimination Check options to define types of artifacts to be eliminated Polynomial trends Polynomial trend is estimated for each epoch and ea
109. Related De synchronization Computation and Parameters for Event Related Coherence Computation and Wavelet Decomposition dialogs 3 Analysis of ERP ERD ERCoh or Wavelet using ERP window We don t describe details in this chapter For more information see below in corresponding chapters But we should to make a number of definitions to simplify understanding of used processing parameters Each task consists of a number of trials The trial is some minimal time interval during which one or more stimuli are presented and subject responds according to the instruction A digital label is defined to each trial according to mean of stimulus stimuli and task instruction This digital labels help to sort EEG sweeps corresponding to task trials for averaging As an example we will consider so called Odd ball task using for P300 studies During this task two different stimuli are presented a standard frequent stimulus and deviant rare stimulus The subject should press a button in response to the presentation of deviant stimulus The whole task will be divided on two parts Let trial corresponding to presentation of standard stimulus in the first part of task have digital label 1 deviant stimulus in the first part 2 standard stimulus in the second part 3 and deviant stimulus in the second part 4 We want to compute ERP corresponding to standard and deviant stimuli in the first and second parts separately Also we want to compute the
110. SOFTWARE FOR ELECTROENCEPHALOGRAM ACQUISITION AND PROCESSING WinEEG Version 2 8 User Manual St Petersburg Russia 2009 IV UE 9 WINEEG SOEIWAREINSTALELDATION eve ee boudeig e ebvsvi ve ed odek tov ovid eet ev ee eit deb edet 11 MITSAR EEG SYSTEM OVERVIEW eiu do eee EG PRAE 21 1 THE EEG RECORDING SYSTEM CONFIGURATION cccceccecssceccecceccscscecceccscscssceccscescsscsccsceecscesceceeceecscsscsceecsscssessescescesens 2l 2 HE ERP RECORDING SYSTEM CONFIGURATION Feb Que ede Ego Celo load Fa RET 23 3 THE VIDEO EEG RECORDING SYSTEM CONFIGURATION csccecceccscscescecceccccscsccscescescuscscescescescsccecescscssesceecscesessescescesens 24 IVEATIN FUNCTIONS PEN 27 LA EEG RECORDING 27 2 MISUAL EBCFANNADVYSIS Td t TAM te NR MM n Ie 27 So BOEPROCBESSENG ersada meon bte TRE t bb RU IAS dat Roach ba beo doe iS a 27 4 COMPOSING A FINAL E td s qa Det 28 5 PRINTING EEG FRAGMENTS PROCESSING RESULTS AND REPORT TEXT cssccseccsccceccscescccsccsccsccesccscesscessescesccusseu
111. To rewind the EEG window right with high speed 92 3 Analysis Toolbar This toolbar is usually placed in the top of the WinEEG window under the main toolbar but can be moved and is used to manage ERP Spectra and Indices windows To show or to hide the toolbar use View Toolbar Analysis Toolbar command To modify button set or to change order of buttons in the Input Control toolbar use View Toolbar Customize Analysis Toolbar command You can also move or delete buttons by dragging them when holding the Shift key pressed 6 T e Display spectra or indices as graphs Graphs mode Display spectra or indices as histograms Histograms mode List spectra or indices parameters in a table Table mode Display spectra or indices as maps Maps mode Map asymmetry for spectra or indices Asymmetry mode Map ratio for spectra or indices Formula Mapping mode Display interaction diagrams Interaction diagrams mode Display ratio dynamics for spectra as graphs Formula Graphs mode Display power spectra or their parameters in spectra window E 15 18 E E Display EEG coherence or its parameters for each channel in spectra window Display average EEG coherence or its parameters in spectra window Display phase spectra or their parameters in spectra window Displays EEG bi spectra frequency frequency plots Displays EEG bi coherence frequency frequency plots Display average spectra i
112. able The EEG recording system based on Mitsar EEG 202 amplifiers model 404 and 400 modifications of system differ in the connected Mitsar EEG amplifiers only and include the doctor physiologist s PC with keyboard mouse printer and USB dongle the EEG amplifiers the photo stimulator the patient s warning button and the power supply 23 WinEEG software receives amplified pre filtered and digitized EEG signals stores them to hard disk of PC for the future processing process the signals in real time and displays them on the PC monitor All functions of recording and analysis are controlled using the keyboard and the mouse of PC 2 The ERP recording system configuration Computer Aanplifier 201 of 2027 E D Mifsar MITSAR EEG 207 nn ARER o OF o T WinEEG 5 Ly e 09 j zi zg 2 2030508 oF OF m c sockets Power cable USE cable a _ Power cable gt Computer _ gt PSY TAS i ji The EEG recording system This system configuration includes an additional PC so called stimuli presentation computer Stimuli presentation computer is connected with EEG recording computed
113. act the beginning of artifact and its duration 4 Beginning of trial the beginning of trials 5 Stimulus onset the stimuli onsets Following additional information is necessary for Beginning of trial and Stimulus onset event types Baseline time interval ms the duration of prestimulus time interval Duration ms the stimulus time interval Poststimulus time interval ms the duration of poststimulus time interval Total duration of trial will be equal to the sum of these tree parameters Check Use digits only button to exclude time events with textual information during adding trials list 22 Export ERP ERD dialog ERP ERD export is used for saving data in a text file readable by other applications Export ERP ERD X Channels Data Waveforms Performance data Time Interval From Begining of Tri From ma OE 0 Step o x Baseline carrectian left from Hone Lenght ma 50 Format Channels in line Add Delete 5 elect all Unselect all Select all Unselect all Groupe in line File row names Append to the end of file column names Cancel C Time samples in file Channels Select the channels you wish to export ERP from Use Add Delete Select and Deselect buttons Groups Select the trial groups for which you wish to export ERP To select or to unselect al
114. al movement Eve blink conmected ears iaverage referent 19 ri Eve blink average referent referent 19 channels 13 channels Similarity 10 800 Similarity 10 800 Similarity 10 800 F Left myagraphy average Right myography average referent 19 channels referent 19 channels Similarity 10 800 Similarity 10 800 Similarity Export first number af artifact free independent components only Number of components for esport 0 Percent of total variance described by first artifact free components with maximal variaance 10 95 Parameters of components for export Volume areas for counting the number af components with corresponding dipole source coordinates Component topograties P dz dr d Y 7 d Equivalent dipole source coordinates mm mm mm m mm mm mm mm LORETA maximum localization ii on LORETA maximum localization i LORETA transfornation matris 0 0 0 0 0 0 11 0 0 0 0 0 0 Braue 4 0 0 0 0 0 0 12 0 0 0 0 0 0 Power of component spectra for selected bandranges 2 2 Percent of power of component spectra for selected bandranges l List of frequency bands lo 0 0 0 0 0 15 0 0 0 0 0 Output name Browse D 100 Parameters of components for output fields group is used for definition list of parameters It includes following fields Check Component top
115. al parameters intervals and amplitudes horizontal and vertical speed and sensitivity scaling marking sites of interest removing artifacts etc 3 EEG Processing WinEEG includes the following methods of EEG analysis 1 Digital EEG filtering 2 Artifacts correction based on ICA decomposition and spatial filtering 3 Automatic artifacts detection and elimination 4 Automated dipole based spike detection 5 Spectral and coherence analysis including topographic power and asymmetry mapping 6 Analysis of EEG indices 7 Topographic mapping of instantaneous scalp potential values spectral parameters and etc using 2 D spherical spline or 3 D LORETA methods 8 Source dipole localization 9 Event related potentials 10 Event related EEG de synchronization 11 Event related EEG coherence 12 Event related wavelet band power 13 Event related wavelet coherence 14 The spectra of EEG independent components 15 Single trial independent components analysis of ERPs 28 16 The grand average spectra of EEG independent components 17 The grand average ERPs of independent components 18 Exporting the data to ASCII file for analysis by another statistical package 19 Computing of grand average EEG spectra grand average EEG coherence grand average ERP grand average ERD for selected set of observation 20 Comparison of EEG spectra EEG coherence ERP and ERD for different subjects groups of subject
116. allowed slow wave power 2 frequency band to be treated as slow wave 223 74 Parameters of ERP ICA spectra dialog Parameters of ERP ICA calculation E X Groups of trials Labels Correct Incorrect Artifact EL STI Subject response processing D efined Define Synchronization Stimulus Artifact processing Level uM 00 Channels Ont EEG Stimulus t1 Threshalds for channels Button channel Mat selected Time interval before m Time interval after lo Add Delete Add all Delete all Load Save 04 1004 Current iteration Cancel Channels Select the channels which signals you wish to process Use Add Delete Select All and Deselect buttons Groups Of Trials The table defines context names for trial groups Name fields and corresponding trial label lists Labels fields Up to 8 different trial groups can be defined For each trial group a label list 1s defined label values in the list are separated by commas 1 2 5 9 The same trial label value may be used in several different trial groups For groups with empty label lists ERP would not be calculated On the right side of the table there are fields for displaying statistical results of trial grouping artifact analysis and response processing The Correct fields show number of trials in each eroup when the patient performed the task correctly The Incor
117. alp maps nor the IC activations are themselves calibrated Rather the original activity units mV and polarities are distributed between the two IC factors the IC scalp map and activation time series For example reversing the polarities of the activation and inverse weight matrices then back projecting the activations through the respective columns of W recovers the original component 47 activities in their native mV units Thus neither sign of scalp maps nor the sign of activations are meaningful in themselves but only their product which determines the sign of the potential accounted for at each scalp channel However IC activation magnitudes may be normalized by multiplying each by the root mean square RMS amplitude of the corresponding IC scalp map The activation units are then RMS mV across the scalp array The matrix W be s found using infomax approach see Bell A J Sejnowski An information maximization approach to blind separation and blind deconvolution Neural Comput 1995 Vol 7 P 1129 1159 Lee T W Girolami M Sejnowski T J 1999 Independent component analysis using an extended infomax algorithm for mixed subgaussian and supergaussian sources Neural Computation 11 417 441 to carry out blind source separation Infomax ICA 15 one of a family of algorithms Cardoso J F Laheld B 1996 Equivariant adaptive source separation IEEE Transactions on Signal P
118. ame C Projects winE EGVideo R M Working folder E ProjectswinEE GVideo R Please INDIES Database of Evacked Potentials ERF Database pathname CAD 00 ERF Working folder 0 ERP y Database of Event Related Desynchronization ERD Database pathname C Projects winE EGVideo Release ERDBASE DBF x Working folder C Projects winEE GVideo Fielease ERD m Database af Event Related Coherence EH Cah Database pathname C Projects iwinE EGVideo Release E RCBASE DEF m Working folder C Projects winE EGVideo Release ERC TE Database of EEG crasscarrelatian Database pathname C Projects WwinE EGVideo R S Working folder C Projects iwinE EGVideo R xs Database Of Event Related De synchronization Database Pathname Enter full path for ERD database or press button to the right of the name field to browse folders Database Of Event Related De synchronization ERD Working Folder Enter full path for ERD working folder or press button to the right of the name field to browse drives and to select a folder Database Of Event Related Coherence ERCoh Base Pathname Enter full path for ERCoh database or press button to the right of the name field to browse fold
119. amics is smoothed by moving average with averaging epoch width optimally 100 ms or 25 bins 6 ERDS 15 calculated as percent of signal power change for each bin in relation to average power during the prestimulus interval R R R x 100 The signals obtained are then averaged similarly to ERPs Following diagram illustrates consequence of processing and analysis steps ERD analysis functional diagram Spatial High order Montage filtering Bandpass bandpass processing artifacts filtering correction FIR filtering EEG datafile Calibration Subject om ae EEG p PE omputing response E relops difference p elimination sroupmg GUERT processing 7 averaging waveforms Database of observations ERP Database of window ERD ERD analysis Wavelet ERP and Wavelet Coherence Analysis The wavelet ERP and wavelet coherence analysis is performed similarly to cognitive ERP computation wavelet ERP and wavelet coherence analysis can be performed only for EEG files recorded together with stimuli presentation by PSYTASK program on an additional stimulus presenting computer These methods is based on signal power and coherence dynamics assessment for the given frequency range by means of source EEG wavelet decomposition Usually 5 wavelet transform is used for signal decomposition Detailed description event related band power computing can be found in Tallon Braudry C Bertrand O Oscillatory gamma activity in h
120. an be selected D Attention Total number of trial groups trial group pairs may not exceed 32 Therefore 219 71 Artifact Rejection Thresholds dialog Artefacts repection thresholds Level ri Level Level Level ri Level re Pore fo B EMO X resp fo Fm fo EMO Pa o EMO Crj Level ri Level ri Level ri Level ri Adi 0 Ad 0 Ad3 Add 0 Ad Ad Biol jo jo jo jo 5 0 Bio 0 Bio Biog 0 Cancel Check channels that will be tested for artifacts and define an individual threshold value for each of these channels 72 Subject Response Processing Parameters dialog You will need to define the following parameters for button processing Subject response processing parameters Group Stimulus Time interval ms Lett Button Right Button y on Press EZ ven e me m cR ap amp Me xv 1T xf SSS EE eo Se gt zw Lett Button channel 8103 ECG Any Level Right Button channel Not selected Consider multiple response as Ix ii Cornmission error Corect response Heset Cancel 220 1 Check Groups for which response
121. an be useful for example for data exported to Statistica software File Define full path for the file to export data to Use the to the right of the name field to choose a drive and a folder Append To Existing File Check this option to append data to an existing file otherwise the file will be rewritten File appending may be useful for arranging data from several investigations in an entire table for further statistical analysis 176 27 Export EEG Indices dialog EEG indices export is used for saving data in a file readable by other applications Export EEG indeces Export EEG indeces C EEG indeces for defined bandranges File HswinE EBGEn sHaeleaseX HDEXSD DDBDOP EXP p cence Export EEG Indices Defines what features of EEG indices are to be exported to an ASCII file Raw EEG indices Writes raw EEG power spectra to an ASCII file Columns correspond spectra to channels and rows to frequencies first line 0 25 Hz second 0 5 Hz The value in a cell means the percent of time when the EEG contained half of waves of the given frequency band EEG indices for the Writes the table of parameters of EEG indices to an ASCII file defined bandranges Columns present channels and each line correspond to an EEG frequency band Delta Theta etc The value in a cell means the percent of time when the EEG contained half of waves of the given frequency band File Define full path for the file to export data
122. analysis of recording interval four indices will be calculated for each EEG channel representing percentages of time when the potential fluctuations had frequencies lying within the given ranges There is no standard algorithm for calculating EEG indices so two methods are implemented in the WinEEG software the first method is based on detection of zero crossings for half wave period calculation the second one on detection of local peaks In either case one additional parameter is used this is the minimum threshold signal voltage for rejecting low amplitude potential changes So a zero crossing will be considered valid if there are two time readouts such that the signal voltage should exceed the threshold for the first readout and fall below the threshold for the second one for opposite polarity signal intervals simply invert the threshold and signal relationships Besides that the potential values for time readouts placed between the above threshold readouts found should not exceed the threshold value In other words low amplitude potential fluctuations are ignored in order to eliminate amplifier noises and external ones from the analysis When detecting local peak values also only those exceeding the given threshold are taken into account 36 The threshold potential may be set as an absolute value in microVolts or as a relative one In the relative case the standard deviation of the signal potential about zero is calculated and half
123. ane EE 109 TO Pies COMPTES VIQCO TILES sce 109 Irt OU COMING A 109 ELG and Video EEG command Lei rude ated 110 ELE PEEL 110 2U FUE Tace Setas ne I 111 21 File Print Preview command He ec EE 111 d HB SALON 111 eiui MEI I Mm I Hu DIE D AE E 111 LO IU INO OC OMINONG a ME I LI OM EIE D ME 112 EIE Eu M I Mm DI E 112 DT THOU CODY COMMM OANIO t deca ti Hat pni pesa hu daba tetilce ouais Utque asd cua ethos UR Oed due 112 PAE CON AON 112 20 COMMOANG ERN 112 S sea Reus TECHN 112 DEM UTI CEAFA COMMON NER RR ETE 113 Video Data COMMGN Ga RUN 113 COMMING ERREUR TERRE m 113 ICCD IAC 113 DOA FANG SCICCUION COMIMONG tt td ttti bout ae E 113 SEd FVGACINEI etel t beet eitis dtes ut a 113
124. another file When you run this command Export video EEG dialog appears This function is useful if it is necessary to prepare a number of video EEG examples to write them to CD The WinEEG program will copy automatically video EEG data video EEG viewer ViewEEG program and some additional service data in selected folder It 15 possible to run this function many times As the results a number of subfolders will be created and the data will be copied in these subfolders lox Edit wiew Favorites Tools Help Q O DP5 i F Back Forward Up Search Folders Move To Copy Address Go Lj DATA1 b AUTORUN INF START EXE WIEWEEG EXE E objects 954 KB E Computer START EXE utility helps to open all copied data automatically by ViewEEG program ViewEEG program is the restricted version of WinEEG program providing reviewing of video EEG data D Attention ViewEEG program requires DirectX 9 0 installation 19 File Print command Print the active window content active file By default the full contents graphs maps or text will be printed unless specific pages have been specified in the Print dialog that 15 displayed on calling this command The exception is the EEG window where you position the two vertical cursors to select the EEG interval you wish to print 111 Use File Print Preview command to preview the document you are going to print Shortcut
125. ansformation For the frequency interval set by the Low Frequency Band parameter signal power 15 calculated and compared with the Maximal Low Frequency Signal Power parameter value If the power calculated exceeds that set by the last parameter then the EEG epoch 15 treated as an artifact To cancel artifact elimination select zero 0 25 Hz limits of Low Frequency Signal Range parameter Note that an EEG epoch 15 treated as artifact 1f low frequency signal power exceeds the limit value for any of the channels 39 6 Finally average spectrum 15 calculated for each separate channel over all non artifact EEG record epochs in the single interval You may think choosing EEG spectral analysis parameters is too cumbersome If so we recommend you use a standard parameter set epoch length 4 sec 5090 overlapping zero order of polynomial trend Hanning time window 0 2 1 25 Hz range of low frequency signal 200 mkV maximal low frequency signal power The duration of the analyzed interval should not be less than 10 sec for at least 4 epochs to be averaged Use other settings and parameter values only when needed to obtain data compatible with that described in the literature EEG power spectra dynamics EEG coherence EEG phase spectra bi spectra and bi coherence can be computed and saved together with EEG power spectra but auto and cross correlations are computed separately and saved in another file Event Related Potentials This secti
126. antly simplifies and accelerates selecting records of interest WinEEG Database functions allow 1 Adding a new file for example an EEG file after an investigation or a spectra file after processing to the database See File Save command 2 To add a previously created data file 3 To sort records patient cards by any criterion field 4 To select a subset of records by a set of criteria 9 To copy or to move a file to an archive 6 To copy a file from an archive to the working directory 153 7 delete a data file and or database record In the top of the Record List dialog window there is a record list Each row in it corresponds to one record in the investigation list file Each column in list corresponds to one field of the patient card form Use Setup Database Pathnames command to define what fields are to be displayed and in what order When Record List dialog 1s opened record list 1s unsorted the first row displays the latest investigation added to the database etc To sort the record list by any field click the corresponding column header To select a record for further processing click the corresponding row so it becomes highlighted In the bottom of the Record List window the patient card from the selected record is displayed see Edit Patient Card dialog Additional data file information 15 also shown there File field displays the name of data file corresponding to selected record
127. arameters Font Choose font name from the list Font Style Choose font style normal italic bold Size Choose font size Effects Check Underline and Strikeout options to set corresponding effects and choose font color 193 Tr Times New Roman Tp Trebuchet M5 Tr Typollpriaht BT F Utah Tr Utah Condensed Sample Display font sample Script Choose appropriate script character set 52 Paragraph dialog Define paragraph format Paragraph Indentation Left Indent from left margin cm Right Indent from right margin cm First line First line indent from left edge of the paragraph cm Alignment Choose paragraph alignment left right or centered 47 Final Report Template List 194 Display list of templates for final reports Choose template you need and double click its name or press OK Final report template list 195 53 Parameters Of signals dialog x Fpl Ay 21 0 B Lt 1 3 Fpz Av 4 FAV 17 3 11 53 F3 4 33 13 5 Fz 24 5 8 10 7 Fa Ay 26 6 AA 3 3 21 0 B bz 4 8 Thay 25 6 10 24 Cay 17 1 53 13 5 Cay zB b bz B 1 4 5 20 9 14 15 1 6 T4 Av 30 4 9 53 4 2 Toa 29 5 8 H1 Ja 229 Pz 18 7 r09 6 9 18 2 0 06 0 1 Bb v 30 5 F 54 40 O1 Ay 34 7 7 51 4 35 5 9 5 12 4 24 19 0 6 Min Insert into repart The table displayed in this window includes next colum
128. arch connected amplifiers If Mitsar amplifiers are not connected now or some problem occurs manual search of connected amplifiers can be performed using Setup Equipment parameters command Is you haven t Security Key you can open protected functions by Access Codes The Access Codes are distributed by Mitsar Ltd Mitsar will give you these codes by requirement if you have purchased the corresponding hardware software configuration The Access Codes are unique for each amplifier box and are active if this amplifier box 15 connected to computer only To generate Access Codes it is necessary to know the information about amplifier box such as its version and its serial number This information can be found using Setup Equipment parameters command The next or similar string will be displayed in Amplifiers type field if the amplifier box 1s connected to the computer Mitsar 201 version 8 serial number 46 20 Equipment configuration x Amplifiers type Mot respond 70 pork Sampling rate Hz Parameters of Synchronization Port Synchronization port to which a slave computer is connected COM 1 Baudrate 57600 Number of bits E Parity None Stop bits 1 Presentation device Parameters of port for external marks Serial port for extemal marks None Baudrate 1310 Humber of bits 4 Parity Even Stop bits Graphics acceleration Method Turm off
129. are selected by corresponding commands on the Analysis menu as listed in the table below In addition for wavelet ERP analysis there is a feature that allows display of EEG oscillation dynamics for the given frequency band as graphs or as bitmaps X axis time Y axis frequency 83 B x j x 2 pump A Fa Speed 30 mms Gain 50 uv Baseline 0 00 ES Heset Low Cut z High Cut Hz Match Hz 5091 Active Groups Averaging frequence bandrange 9 1 O 2 ignore 3 O 4 Go EX i WinEEG WinErd3 Natalya File Edit wiew Format Recording Analysis Setup Window Help For Help press F1 From m fo Duration m end Step ms 4 Number Baseline Baseline used Length ms Channels ERPs are depicted as graphs arranged in columns by channels Groups and in rows by trial groups Groups ERPs are depicted as graphs arranged in columns by trial Channels groups and in rows by channels Time Groups ERPs are depicted as maps arranged in columns by time Mapping readouts and in rows by trial groups Groups Time ERPs are depicted as maps arranged in columns by trial Mapping eroups and in rows by time readouts Formatted Page gt ERPs are depicted as graphs and maps ERPs are depicted as graphs and maps Graphs are placed according to
130. aseline list EEG Window The global field power 15 calculated according a formula D Attention If active electrode is defined as GFP the global field power will be displayed in GFP 0120 uli i Modifying Channel List Press Add button to add a new line to the end of the montage channel list Press Insert button to add a new line above the currently selected one Press Delete button to delete all selected lines from the montage channel list 3 Montage Parameters Referents dialog Use the Channels tab of the Montage Parameters dialog to define lists of channels to be included when calculating Av AvL AvR and AvW referents You can also choose a montage from the montage list see Setup Montage List command Montage Name This field initially contains the name of the default montage from the montage list Use down arrow button to select a different montage from the list for use as a new default You can also rename the selected montage The Left Average AvL group defines the list of channels for the AvL referent To calculate the AvL referent signal the encephalograms of the marked checked channels are averaged The Right Average AvR group defines the list of channels for the AvR referent To calculate the referent signal the encephalograms of the marked channels are averaged The Average Av group defines the list of channels for the Av referent To calculate the Av referent signal the en
131. atient card choose a montage and check it When these actions are completed successfully a new EEG window will be displayed on the screen 5 Run the Recording EEG Monitoring command Visually check the quality of the live EEG displayed in the new window If any channel is acquiring EEG poorly re install the corresponding electrode s Check EEG acquisition quality using a monopolar montage without averaging 6 Run the Recording EEG Recording command to start recording signals to a file To stop recording run the Recording EEG Recording command once more One fragment of the EEG will be recorded Record another fragment if necessary Before recording a fragment its name should be set using the Fragment list on the Recording bar Input Control Toolbar If photo stimulation 15 necessary set its frequency using arrows in the PS Frequency field of the Recording bar start the EEG fragment recording turn the photo stimulator on using the Recording Photostimulation on off command wait for the time needed change the photo stimulation frequency or turn the photo stimulator off and so on After finishing the photo stimulation procedure stop EEG recording 7 Stop EEG acquisition using the Recording Stop command 8 Save the newly created EEG file into the database using the File Save command 9 Remove the electrodes and let the patient go D Attention To avoid data loss do not carry out Step 9 before Step 8 10 Analyze the newly
132. atient name Patiend ID Diagnosis Date of birth from NENNEN In Address DEE Existed in the working folder Backuped ID field contains a text string that must be present in corresponding field of database record If the text defined for search is shorter than in the database a substring 15 searched Symbol case 15 ignored Blank spaces before and after the text are deleted If the ID field in the search condition contains then records containing ABC abc AbCXXxxXX in their ID fields satisfy this condition Date From To fields define the interval of EEG acquisition dates current year for example To enable automatic search by date use DD MM Y Y Y Y date format Time From To fields define the interval of EEG acquisition times before noon for example To enable automatic search by time use HH MM SS time format 159 Investigation field contains a text string that must be present in corresponding field of database record see also ID field Patient field contains a text string for example patient name that 1s to present in the corresponding field of the database record see also ID field Patient ID field contains a text string that must be present in the corresponding field of the database record se
133. ation for corresponding parameters values using during searching of spike like waves Amplitude temporal parameters are the following Dur 1 Duration 1 defined as the time interval between two successive maxima or minima of an EEG wave Durl 2 Duration 2 defined as the time interval between two successive inflection points 1 points where the absolute value of the first time derivative of the wave form has a maximum value of an EEG wave Dur2 Amp Ampz UJ EUER 9 203 Duration A defined as the time interval between the beginning and the pick of an EEG wave DurA Duration B defined as the time interval between the pick and the end of an EEG wave DurB Amplitude A measured from the beginning to the pick of EEG wave Amplitude B measured from the pick to the end of EEG wave AmpB Amplitude measured from the baseline zero voltage to the pick of EEG wave AmpZ Slope 1 defined as the maximum magnitude of the first time derivative during the leading edge of an EEG wave SII Slope 2 defined as the maximum magnitude of the first time derivative during the trailing edge of an EEG wave SI2 10 Sharpness defined as the second time derivative of an EEG wave at its pick d P d t Dipole and spatial parameters fields define a usage and limitation for corresponding parameters values using during searching of spike like waves Dipole and spatial parameters are the following 1
134. ation programs are used during EEG acquisition see Input Control toolbar There are two types of photostimulation programs rhythmic and flashes A rhythmic photostimulation program may consist of several from one to twenty steps For each step the photostimulator flashes with constant frequency and power for a certain time For photostimulation by single flashes three parameters are set number of flashes minimum interval and maximum interval in milliseconds WinEEG automatically creates and uses a sequence of intervals with random durations within the range from minimal to maximal value defined Name Select a photostimulation program to modify or enter a new name Type Choose photostimulation program type Rhythmic Single flashes or Pairs of flashes Duration Define duration in seconds for each step of rhythmic photostimulation program Frequency Set stimulation frequency for each step of the rhythmic photostimulation program If zero frequency value 15 set photostimulator will be off during that step Power 261 Set flash power for each step of rhythmic photostimulation if power control is enabled Number Of Flashes Set the number of single flashes or number of flash pairs for stimulation by flash pairs Minimal interval Set minimum interstimulus interval for stimulation by single flashes or flash pairs Maximal interval Set maximum value for the interstimulus interval for stimulation by single flashes or f
135. aue 126 115 Pop up menu of EEG window Add Spike command E 128 116 Pop up menu of EEG window Delete Spike 126 117 Pop up menu EEG window Change Channel 4 eene n nennen eene nnne nns 126 118 Pop up menu EEG window Copy EEG command 129 119 Pop up menu EEG window Copy Spike command eene eene nnn nnn nennen eene essen 129 120 Pop up menu of EEG window Copy EEG to Report eese eene eene nnne eene 129 121 Pop up menu of EEG window Copy Spike to Report command 129 CONMATE MR r M 129 12 ETE 129 PGI SUS LADLE M nem 129 122 E E ia 129 FOAD ASYE COMTAN PP 129 Analysis Formula Mappi ITI cie EE NS TENEN E REE 130 12 Formula COMMANA osinn i enen ces aeey NEENA tro Iso EE EE 130 128 Analysis Interaccion diapram tro 130 130 Analysis Power Spectra Autocorrelations
136. ave not additional digital TTL inputs another analog button is connected to ECG input to measure subject reaction Last modification of button has two output levels left button low level right button high level and provide all possibilities as digital button different modification of buttons Incorrect settings of button signal processing can be potential source of errors Attention Different parameters of processing of subject reaction should set up for 62 Main features of EEG window are listed below 1 EEG Acquisition During EEG recording additional information is displayed in the window DNEWOOOO EEG Test 2 11 05 15 10 x jme 300 300 4 300 300 3 300 C3 Ret 300 4 300 4 T5 Ret S00 Fz Ref S00 fcr 1 300 S00 icm m Ga LJ m ca c ca c cO eO cO eO eO eO eO Z zT zT zT zT zT zT a o o o o x Es 4 H Current time is displayed on the left top corner of the window Total duration of EEG recorded to the hard disk is shown on the left bo
137. avelet decomposition Step Choose step for calculations within a certain frequency range Wavelet Width 217 Choose wavelet width in time domain Wavelet width can be in absolute units ms or in cycles Cycles mean different absolute wavelet width for each frequency On the other hand in this case resolution will change proportionally for time and frequency domains Special papers recommend the value of 5 cycles for this parameter But each case may require a different specific value for this parameter Smoothing This parameter is set in time readouts N and defines filter sliding average width for ERD curve smoothing for each separate trial prior to averaging Subtract ERP from raw EEG If this option 1s checked then before calculating EEG oscillation power ERPs will be subtracted from source data to eliminate their effect and only induced activity will remain 69 Wavelet Coherence dialog To perform wavelet coherence calculation additional information on stimuli presentation structure in each trial is used together with source data To group trials by stimuli types or by response task trial labels are used These parameters are defined beforehand when creating editing stimuli presentation protocols by means of PSYTASK program installed on the presenting computer Wavelet coherence Groups of trials Labels Correct Incorrect Artifact ea c Pa Group differences E 4 3 5 5 Choose
138. ayed in this field 42 Fragments List dialog List of fragments x Heading 08 31 10 Cancel Choose fragment and press OK or double click fragment name Click Delete to delete selected fragment from EEG file Click Modify to change name of selected fragment The Modify fragment name dialog will appears then 43 Modify fragment name dialog Modify fragment name Fragment name 08 31 07 T Enter new fragment name and press OK 188 44 Deleting of selected EEG fragment Select what kind of data are you going to delete and press OK button 45 Deleting of video data Video data deleting Select what kind of data are you going to delete and press OK button 189 46 Modify Trial Labels dialog Trial list 1s there on the left of the dialog Select trials to edit labels for Click a trial to select it Use Shift and Ctrl keys to select multiple trials Modify trial labels Selected Select all Value Old value Mew Value Load Save D Cn Toc DR D B qe I C c3 c3 c3 c3 63 63 6 c3 6 c3 c 6 AA c3 c3 Press Select button to se
139. ble USE cable z Power adapter for medical devices Power cable m Patient warming Microphone lution TR bight source N Power cable Video aut Video camera e Camera remate Power adaptes control The video EEG recording system with one camera 25 Coupes Amplifier 201 or REG 26 MITSAR EEG 202 Mirsar Kevhoand 1 2 O20 Fe FBN WinEEG o 655 FW Fer o T3 Cz Ta O O0 CP3 cpa Tra 6 o O2 T LO adeo capire M x oO o a oO x Printer Oo Oo O O in Video In N a H USE cable s xi Power cable Power sockets jE Poser cable Power adapter medical devices button T 5 IR light source E Widen out Power cable Video camera Camera remate Poser adaptei control C EE Second video camera Video ont The video EEG recording system with two cameras One or two video cameras and microphone can be connected to doctor s PC for synchronous recording of EEG and video movies WinEEG software receives the amplified pre filtered digitized EEG signals stores them to hard d
140. calculated for each channel P alpha P beta P delta P theta and displayed whenever Formula mapping were selected 98 12 Averaging Groups Bar Active Groups 1 ac e 2 nogo 10 3 4 None Averaging frequence bandrange This bar is located at the top of the ERP Window and is used to choose which groups may be displayed and to select an active group 13 ERP Bar This bar 15 placed on the right edge of the ERP Window and is used to set graph or map size vertical and horizontal scaling for graphs color scale sensitivity and time readouts for ERP mapping Time interval From m Duration ms end Maps From m Step ms Humber 10 Baseline Baseline Mot used Length m Al 99 14 Video Window The video data corresponding to position of slider see EEG window is displayed in this indow Use command View Video Window jo show hide this window unu in ww 7 E TR 74 a cited at Menu Commands File Menu Commands 100 The File menu offers the following commands New Open EEG Database Open Another Database EEG Spectra EEG Cross correlations EEG Indices ERP EP File ERD File ERCoh File Open File Import EDF Data Import Data Close Save Sav
141. ce between instantaneous values at the markers A Peak to peak EEG amplitude for selected interval difference between maximal and minimal values Average signal frequency Photo stimulation frequency For EEG spectra window 6 Measured parameter value 2 Frequency at the marker position 2 For ERP window V Measured potential value uV T Time from the last preceding stimulus ms stimulus number 1s indicated by number before colon Frequency Hz for time frequency plots P lt Statistical significance Indicator Description CAP Caps Lock key locked NUM Num Lock key locked SCRL Scroll Lock key locked 94 5 Print Preview Control Bar ieee Two Page zoom in Close Print Call Print dialog to start printing document Next View next page Previous View previous page Two Pages One Page View two pages or one page at a time Zoom in Zoom page in Zoom out Zoom page out Close Close Print Preview 6 Filters Bar x Speed 20 mm s nv Baseline 0 00 n Low Cut is High Cut Hz 30 Hz 50 0 1 This bar is usually placed at the top of the WinEEG window but can be moved and is used to edit a number of parameters for the EEG window or active EEG file 663499 Use Speed list to choose horizontal scale simulating paper speed You can also use and keys
142. cephalograms of the marked channels are averaged 147 Montage parameters X Card Channels Referents Colors View Electrodes Montage name Aight average 47 Pol Fp Fo2 Pa FF F3 v Ce T5 Pe 4 v M 02 Lett average Pol W M C3 M C 14 T5 MPa Pe P4 02 ch Di m me seb sdg F d Ada Weighted average Bw Avv zRet Modify transformation matrix Average Av Pol I Fpl Fp 2 Fr MF M C Iw v 14 Th M Po P4 v M 02 Ada The Weighted Average AvW group defines list of channels and weights for the AVW referent You can choose a transformation weight matrix from the list or define your own To define a transformation matrix press Modify transformation matrix button The Transformation Matrix for Weighted Average Referent dialog will appear 4 Montage Parameters Colors
143. ch channel and 201 eliminated from source signal Additional parameter polynomial order Slow waves Epochs with too large slow wave signal component cause by eye motion or other artifact are eliminated from averaging Additional parameters 1 maximal allowed slow wave power 2 frequency band to be treated as slow wave 56 Nonlinear analysis parameters dialog Nonlinear analysis parameters Interval Selection f Fragment 12 2407 C Ful EEG file Channel Fef Number of samples 1 Sampling rate 250 Step 1 Lag ms det Estimate Plot of attractor Store plot in file C 2D File name Default Browse 3D ae EN Display Step 2 Theiler Window ms det auta Estimate Step 3 Embedding dimension 102default 10 N det 1000 Fast FIN Step 4 xz remi Shep 5 for all channels Additional processing All channels Y Parameters woo Default Terminate Cancel Attention This window helps to define parameters of nonlinear analysis and run processing utilities The nonlinear analysis is optional function and can be ordered separately by special order together with description of this window 202 58 Spike detection dialog Spike detection X Source data for detection algorithm C ICA components Amplitude temparal parameters Duration 1 1 ms So
144. command To arrange buttons in the Input Control toolbar use View Toolbar Customize Input Control Toolbar command You can also move or delete buttons by dragging them when holding the Shift key pressed Click To Start EEG acquisition and monitoring without recording to hard disk Start EEG fragment recording to hard disk Click arrow to open list of fragment names Pause EEG acquisition monitoring and recording He OE Stop EEG acquisition monitoring and recording and switch to EEG view mode Show hide Main Video Window Show hide Additional Video Window Change the size of Video Window Start stop recording of Video signal synchronously with EEG recording Start calibration signal 0 5 Hz 0 1 Ohm acquisition and monitoring in a new EEG window without recording to hard disk Reset DC component View calibration efficiencies of the amplifiers Measure electrode impedance E ED e 8 Turn rhythmic photo stimulation on or off Click arrow to open menu of photo stimulator colors White Red and Red With Increase photo stimulation frequency Decrease photo stimulation frequency EA Turn on off a photo stimulation program Click arrow to open photo stimulation program list Start or stop a stimuli presentation program Rewind the EEG window left with high speed Playback the EEG window left with normal speed To playback the EEG window right with normal speed
145. command to size the active window by means of arrow keys The cursor will change its shape to Use arrow keys to move the window Press ENTER when the window reaches the necessary position Shortcuts Keys CTRL F7 200 Minimize command System menu Minimize the window to an icon Shortcuts Title bar Keys ALT F9 201 Maximize command System menu Maximize an application window to screen size or a document window to application window size Shortcuts Title bar Double click title bar Keys CTRL F10 202 Next command document window System menu Activates next document window in order of opening time 141 Shortcut Keys CTRL F6 203 Previous command document window System menu Activate previous document window in turn by time of opening Shortcut Keys SHIFT CTRL F6 204 Close command System menu Close a document window or application Shortcuts Title bar Keys CTRL F4 to close a document ALT F4 to close WinEEG 205 Restore command System menu Restore a minimized or a maximized window 142 Dialogs I Montage Parameters Patient Card dialog Use the Patient Card tab of the Montage Parameters dialog to enter data in the patient card You can also choose a montage from the montage list see Setup Montage List command Montage parameters X Fatient Channels Referents Colors View Electrodes Montage Mame
146. commend you to use this option with rather slow computers Use Source button to specify compression parameters if corresponding video capture card support on line compression Frames per second Select frame rate if it 1s possible Video format Press this button to specify parameters of video format Video Source Press this button to specify parameters of video capturing Audio input device Select audio input device Audio source Press this button to specify parameters of audio input Audio Compressor Select on line video compressor The compressors MPEG Layer 3 will be the best for many system configurations Would you like to capture audio Check this button if you would like to capture audio signal Video block length Specify minimal length of block of video data placed into one file By another words each specified seconds the old video file will be closed and new file will be created Attention Please specify all parameters of Video format Video source and Audio source carefully The quality of recorded signal will depend on these parameters Unfortunately corresponding dialog boxes are unique for each video capture and audio capture devices Please look for information about them in corresponding operation manuals 271 117 Equipment Configuration dialog Amplifiers type In this case the version and serial number of amplifiers box will be displayed I O Port Choose COMI or 2 port to connect encephalograph Atte
147. conjunct time series This time series was used for assessment of W matrix Let X conjunct time series U 4 j where X individual EEG of j th subject and U denote conjunction operator j The unmixing matrix was estimated in accordance to the next equation Xe S using Infomax algorithm Then individual activation curves for each subject were calculated as following W X 50 For each individual and for each independent component power spectra were computed Individual spectra of components grand average spectra of components and component topographies are displayed in ICA window and are available for analysis Following diagram illustrates consequence of processing and analysis steps ICA averaged spectra analysis functional diagram Spatial Montage filtering Bandpass processing artifacts filtering correction EEG datatfiles Calibration Compute averaged independent Concatenate Decompose Artifacts epoch from to elimination different component EEG files 1 spectra EEG database records ICA selection window Computing and analysis grand average independent components spectra This procedure is run by pressing button ICA in Database dialog window for EEG database see below 4 The grand average ERPs of independent components The independent components of average ERPs are computed using selected 1n ERP database array of individual subject or observat
148. cord Search Parameters dialog This dialog allows selection of criteria for record filtering In other words only records satisfying the defined search conditions would be displayed in the results list and the others would be ignored The criteria set 15 saved and then used any time when the Record List dialog is opened This logic facilitates repetitive searches over a certain subset of the database records for example only with data 249 acquired during last month But it may also cause mistakes and complications when looking for data If you find that some records have suddenly disappeared from the database first of all check the search criteria Each edit box the Base Record Search Parameters dialog defines one search criterion record satisfies search conditions if it contains all features that have been defined Blank fields are ignored during search Here 15 the list of search criteria that can be defined ID field contains a text string that must be present in the corresponding field of the database record If the text defined for search is shorter than in the database a substring is searched Symbol case 15 ignored Blanks placing before and after the text are deleted If the ID field in the search condition contains then records containing ABC abc AbCXXxxXX in their ID fields satisfy this condition Database parameters Databases of raw data Databases
149. ct the method of graphics acceleration that you prefer Default Turn off Access codes Enter 8 characrters access codes into these fields see above 218 Appendix 1 Final Report Generation Setup Programming Language for Automatic Final Report Generation System Automatic Final Report Generation dialog uses a programming language developed for the purpose of simplifying the creation of hierarchical menus that are used for selecting specific wordings By means of this programming language you can develop practically any structure for calling wording interactive menus The developers however made their aim to design as simple and convenient a language as possible and not to create the most perfectly general hierarchical menu system A source for a hierarchical menu system is an ASCII file created by any text editor and containing information on future structure of interactive menus When menus are created the text 15 compiled by a special compiler FRC EXE that generates a resource file used by the automatic final report generation system The resource file name is mandatory EEGFR RES The compiler interprets menu description If an error occurs compiling process breaks and an error messages 15 generated containing the source line number and a brief error description If no errors are detected a message about successful compilation 15 displayed and a corresponding resource file is created Command line syntax to call the compiler
150. cut Input Control toolbar P 89 Analysis Final Report command Open a Final Report window for the active EEG file When opening the Final Report window WinEEG is looking for a corresponding file in the EEG database working directory RTF file with the same name as the active EEG file If the final report file 1s found it 1s opened in the Final Report window and can be read and edited If not found a new file 1s created and Patient Card contents are inserted in it automatically Shortcut Main toolbar 90 Analysis Signal Parameters command Open Parameters of Signal dialog window The parameters of signals Amplitude from pick to pick approximated frequency and voltage difference will be measured for selected by vertical markers time interval 91 Analysis EEG Mapping command 123 Open an EEG Mapping window for active EEG file You can open several Mapping windows for one active EEG file but for different intervals Use vertical markers in the EEG window to mark an interval of interest An interval for mapping must not exceed sec Raw data 15 processed according to montage parameters before mapping ECG channels are excluded automatically Electrode coordinates are additional parameters for maps see Montage parameters Electrodes dialog Incorrect coordinate settings can disable mapping monopolar montage for the active EEG window before calling this command D Attention EEG data reformatted to a bipolar
151. d 1s used to define the bandwidth and to suppress AC line interference at 50 60 Hz It uses filters with infinite impulse response IIR characteristics that most accurately simulate the RC circuits used in paper chart recorders In other words IIR filters allow EEG recordings that most closely mimic results achieved by means of paper chart recorders IIR filters with different order are used for various goals Low cut filters are first order so signal suppression outside the pass band 15 small 6 dB per octave High cut filters are second order They signal suppression at stop band 15 equal to 12 dB per octave notch filters are twelfth order This filters have the high suppression of at 50 60 Hz more then 40 dB The notch filters with different stop band can be used in dependence on settings 45 55 40 50 35 65 55 65 50 60 or 45 75 Hz The additional combinations of filters are also available 45 55 amp 95 105 40 50 amp 90 110 35 65 amp 85 115 55 65 amp 115 125 50 60 amp 110 130 or 45 75 amp 105 135 Hz The last combinations of notch filters can be used for suppression both first and second harmonics of AC line interference Parameters of filters mentioned above can be set in the montage parameter list or by means of the Filters bar The disadvantage of these filters 1s that they shift signal phase The second method can be used to detect signals in a certain frequency range for example when calculating event relat
152. d automatically in the EEG database working folder and to be opened together with the active EEG file In addition the patient card 1s automatically inserted in the text when generating a new final report Second the EEG database enables the final report file to be backed up automatically along with EEG files Third WinEEG enables the insertion of templates 1n the final report text You are not obliged to use the built in WinEEG final report editor To use Microsoft Word and to keep all the advantages of the built in editor you should install MS Office 2000 and customize WinEEG for using Microsoft Word see Setup Final Report command 73 3 EEG Maps Window This window displays maps of instantaneous ERP values for a selected EEG interval The EEG interval is divided into non overlapping epochs with length defined by the Step parameter value Thus the number of maps displayed depends on the selected interval duration and on the Step parameter value For each channel and each epoch time averaged ERP values are used as input data for an interpolation algorithm Under each map there are figures displaying the beginning and the end of the averaging epoch relative to the first time readout of the selected EEG interval Patient Dmitriev Dmitry Date of birth 1975 Date 1170272001 Fragment M 32 40 ms 40 48 ms On right side of the window there 15 Maps bar In the top of the bar there 15 a color scale and bel
153. d beforehand to be processed But total length of all blocks that can be loaded into RAM is limited Note that processing of a menu block is finished in two cases either after the last menu in order 15 processed or after a break control transfer command is executed The system of hierarchical menu processing completes its functioning when processing of the first in order block described in the hierarchical menu program 15 finished 50 if processing of any block in the program except first block 15 not described explicitly 1n control transfer commands such a block will not be used Finally menu header processing logic shall be fixed If no header 1s described for next menu in order it does not change the header set previously Otherwise two situations may take place If menus of one block are processed their headers will be consequently replacing one another If a block was loaded and a menu with a header is processed the header will be changed But after the block 15 processed completely the header defined in the block that has been previously called and 15 currently being processed will be restored 3 Language Syntax Notation Convention Common notation conventions will be used in syntax descriptions as it takes place in MS DOS and in a number of programming languages like Assembler or C A key word or a syntax expression not in brackets 1s directly present in the program Text in square brackets 1s not mandatory to be present
154. database or in the archive 10 File Open File command This command uses the Windows standard file open interface to open a previously recorded data file EEG EEG spectra etc 1n a new window You can open more than one file Use the Window menu commands to switch between opened files See Windows 1 2 command When you run this command a File Open dialog appears 11 File EDF Data command This command opens EDF files and converts them to EEG format When you run this command a File Open dialog appears After selection of appropriate EDF file a Import of EDF data dialog will appear on the screen 12 File Import Data command This command opens files of other formats and converts them to EEG format When you run this command a File Open dialog appears 13 File Close command Close all windows for the active data file EEG or others WinEEG will ask about saving changes before closing the file 109 Shortcuts Main Toolbar Bi Mouse Click icon in the right top corner of the file document window Or double click the window document icon in the left top corner of the window For different file types different icons are used as follows m for EEG files for final reports for potential maps for EEG power spectra auto cross correlations for EEG indices for biofeedback files for ERP ERD and ERCoh 14 File Save command This command saves the active file If th
155. dependent component spectra command Compute ERP for independent component of EEG and open ICA window The Parameters of ICA spectra calculation dialog will be displayed on calling this command 113 Analysis Independent component spectra command Compute ERP for independent component of EEG and open ICA window The Parameters of ERP ICA calculation dialog will be displayed on calling this command 114 Analysis Comparison of results command Run this command to compare spectra ERP or ERD The results can be compared between different conditions and different subjects or with normative database The Processing results comparison dialog will be displayed on calling this command 115 Pop up menu of EEG window Add Spike command Run this command to add spike label for selected channel and time sample 116 Pop up menu of EEG window Delete Spike command Run this command delete selected spike label 117 Pop up menu of EEG window Change Channel command Run this command to change main channel for selected spike label 129 118 Pop up menu of EEG window Copy EEG command Run this command to copy EEG time interval into clipboard for selected spike 119 Pop up menu of EEG window Copy Spike command Run this command to copy spike waveform into clipboard for selected spike 120 Pop up menu of EEG window Copy EEG to Report command Run this command to copy EEG time interval into text of final report for selected spike 121 Po
156. derline the application of ICA for analysis of array of individual EEG and ERPs are as follow 1 summation of the electric currents induced by separate generators 15 linear at the scalp 46 electrodes 2 spatial distribution of components generators remains fixed across time 3 generators of spatially separated components temporally independent from each other for review see Onton J Westerfield M Townsend J Makeig S Imaging human EEG dynamics using independent component analysis Neuroscience and Biobehavioral Reviews 2006 V 30 P 808 822 This problem can be formulated mathematically as follow Let 1s raw EEG signal recorded from i th electrode i 1 t time 5 is the signal from j th blind source j 2 1 M placed inside the brain Let X r is the sum of 5 f with different waves X t s J Here A is a matrix of weights The task is to recover a version u f l of original sources 5 by finding a matrix W A number of methods as principal component analysis PCA suggest that the sources 5 7 uncorrelated u u 0 V ij In contract with decorrelation techniques independent component analysis ICA 1s imposes a much stronger criterion statistical independence required that all second order and higher order correlations of 1 are zero Statistical independence means the joint probability density function pdf of the output
157. dialog Use the Colors tab of the Montage Parameters dialog to define colors for depicting channels You can also choose a montage from the montage list see Setup Montage List command Montage Name This field initially contains the name of default montage from the montage list Use down arrow button to select a different montage from the list for use as a new default You can also rename the selected montage Channel List The table of channels in the montage is placed on the left side Each row corresponds to a channel in the montage don t confuse them with the channels in the acquisition list The montage channel list includes channels that will be displayed during the monitoring and processed Columns correspond to channel parameters for more info see Montage List Channels dialog 148 To change colors for selected channels how to select channels see Montage Settings Channels dialog click one of the color buttons located to the right of the channels table Montage parameters X Fatient Card Referents Colors Electrodes Notch Baseline 1 1 0 3 0 53 Hz 50 0 1 0 00 uv 2 Fp2Ref 0 3 0 53 Hz 5 50 0 1 0 00 uv 3 FRRef 0 3 D53Hz 30 5000 2 0 000 4 F32Ref 0 3 053 2 30 5000 2 0 000 ps 5 Duv s 0 3 0 53 30 5000 2 0 00 F Ref 03 053 2 30 5010 1 0 00 uv
158. dialog Graphics Page Format Dialog EEG Bandranges dialog Parameters of Bandpass Filter dialog and Equipment Configuration dialog The ERP and other mentioned above studies can be performed 1f EEG 15 recorded synchronously with stimuli presentation The additional signal from special micro switch can be recorded for estimation of reaction time and task performance The auditory and visual stimuli can be presented by PSYTASK program developed by Mitsar Ltd or by conventional stimuli presentation software for example Presentation or E Prime program An additional computer is used for stimuli presentation Both computers should be connected by null modem cable Equipment preparation for performing ERP studies The preparation of computers for ERP studies will be describe below only for using the PSYTASK program for the stimuli presentation The information concerning preparation of computers for using other presentation software can be found in corresponding user manuals I Installation and preparation PSYTASK program 1 Install PSYTASK program To do this installation insert CD with PSYTASK setup program and run SETUP Follow the instruction on the screen 2 Run PSYTASK program 3 Perform Modify Synchronization Parameters Windows XP command and check parameters of Serial Port for External Synchronization The default parameters are the next Baud Rate 57600 Word length 8 Stop bits 1 Parity NONE You can change these paramete
159. ding Evoked potentials ERP database 3 Event related de synchronization The event related de synchronization of EEG will be computed and saved automatically to corresponding Event related de synchronization ERD database 4 Event related coherence The event related coherence of EEG will be computed and saved automatically to corresponding Event related coherence ERCoh database 5 Wavelet band power ERD The event related de synchronization of EEG will be computed using Morlet wavelet decomposition and saved automatically to Event related de synchronization ERD database 6 Wavelet coherence ERCoh The event related coherence of EEG will be computed using Morlet wavelet decomposition and saved automatically to Event related coherence ERCoh database 7 EEG spectra and coherence Power spectra of EEG and EEG coherence will be computed and saved automatically to corresponding EEG spectra database 6 EEG independent component spectra separately for each selected EEG record The results will be saved in specified folder as separate files Check Create report button to generate automatically the processing report The compressed results of processing and processing errors will inserted to this report The processing report will be useful monitoring the processing results and allow estimate their correctness Processing File field displays the name of the file currently being processed I0 Averaging Spectra dialog The Averaging
160. e The Adjust trial synchronization using synchro impulse dialog is displayed after calling this command 42 Edit Change polarity command Change polarity of signals for selected list of channels for the active EEG file The Change signal polarity dialog is displayed after calling this command 43 Edit Load Trial List command Load trial list from ASCII file This feature is implemented for compatibility with Neurobotics EEG system The format of trial list file is follow EventTable V2 0 00024118 1 11 Ls LI 00024924715 44 00025331 Ll 41 1 115 39 00026144 1 4 d Where fist column is sample of trial beginning second column type of event 1 trial third column trial label used for trials sorting during ERP computation 44 View Toolbar gt Main Toolbar command Run this command to show or to hide the main toolbar containing shortcut buttons for most frequently used WinEEG menu commands such as Print See Main Toolbar to learn how to use it 45 View Toolbar gt Input Control Toolbar command Run this command to show or to hide the Input Control toolbar containing buttons used to manage EEG acquisition and scrolling See Input Control Toolbar to learn how to use it 46 View Toolbar gt Analysis Toolbar command Run this command to show or to hide the Analysis toolbar containing buttons used to manage spectra indices and ERP windows See Analysis To
161. e As Compress video files Export Data Export EEG and Video EEG Print Page Setup Print Preview Print Setup Exit Edit Menu Commands Creates a new EEG file Opens a source data record from the database Opens a file from the database of processing results an EEG spectra file an EEG auto and cross correlation file an EEG indices file an ERP file an event related EEG de synchronization file an event related EEG coherence file Opens a file from hard disk containing source EEG or processing results Import of EDF data file Converts data from another format to WinEEG format Closes the active file Saves the active file under its current name Saves the active file under another name Compress or recompress video files by selected method Writes the data file in 5 binary or another format Copy selected part of EEG record to another file Prints the active document Sets parameters for a page to be printed Displays the document as it will be printed Chooses a printer and sets parameters for it Quits WinEEG The Edit menu offers the following commands Undo Cut Copy Paste Clear Select Clear Clear All Video Data Find Replace Find Selection Find Fragment Add Label Delete Label Patient Card Undoes the previous edit action Mark selected time interval of EEG record as artifact Removes the selection and places it on the clipboard Copies the selection or
162. e EEG file and opens an ERP window You can open several ERP windows for one active EEG file but for different intervals ERPs can be calculated only if presentation of visual auditory stimuli was carried out synchronously with EEG acquisition After calling this command a Parameters for Event Related Potential Computation photostimulation dialog or a Parameters for Event Related Potential Computation stimuli presentation dialog is displayed to define additional processing parameters depending on whether source data type 1s photostimulation EEG or stimuli presentation EEG Raw data 15 reformatted according to montage parameters before processing ERP maps choose a monopolar montage for the active EEG window before calling this command D Attention EEG reformatted to a bipolar montage cannot be mapped If you wish to view Electrode coordinates are additional parameters for maps see Montage parameters Electrodes dialog Incorrect coordinate settings can disable mapping Shortcut Main toolbar 108 Analysis Compute ERD command Calculate event related de synchronization ERD for the active EEG file and opens an ERP window ERD can be calculated only if presentation of visual auditory was carried out synchronously with EEG acquisition After calling this command Parameters for Event Related De synchronization Computation dialog is displayed to define additional processing parameters 127 Raw data 15 reformat
163. e active montage parameters i e the montage currently selected by the user Channels not included in the list of channels to process are excluded from the reformatted and filtered multi channel record The entire record interval 1s divided into equal parts epochs The length of an epoch 15 defined by adjusting the Epoch Length parameter in the menu displayed by Analysis Spectra Epoch Length may be set equal to 1 2 or 4 sec Overlapping of the epochs 15 also set as a parameter when dividing the record interval into epochs If Overlapping 15 set equal to 5090 beginning with the second epoch each the first 5090 of each epoch overlaps the final 5090 of the previous epoch After the interval 1s divided into epochs separate calculations are performed for each channel For each EEG epoch polynomial trend parameters are computed and the trend is compensated The order of the polynomial trend is set by means of the corresponding parameter and can be chosen from 0105 If zero trend order 1s chosen only the constant DC component 15 eliminated To suppress energy infiltration through filter side lobes each epoch is smoothed by a time window Bartlett Hanning and Welch time window types can be selected If a rectangular time window 15 used then energy infiltration through side lobes would not be suppressed and in this case there would be no sense in using half overlapping analysis epochs The power spectrum is computed by means of quick Fourier tr
164. e also ID field Diagnosis field contains a text string that must be present in the corresponding field of the database record see also ID field Date of Birth From To fields define the range for dates of patients birth for example from 01 01 1950 to 31 12 1959 To enable automatic search by date use DD MM Y Y Y Y date format Sex field signs patient sex M or F Editing note what about trans gendered individuals Address field contains a text string that must be present in the corresponding field of the database record see also ID field Note field contains a text string that must be present in the corresponding field of the database record see also ID field Check Existed in the working folder option to select only records corresponding to files existing in the working folder Attention Using this condition may significantly slow down the database search Check Backed up option to select only records corresponding to EEG files that have been backed up at least once Press OK button to accept search conditions Press Clear button to clear all fields 12 Backup Data To Archive dialog To backup a data file means to copy it to an archive on some disk If the data file 1s larger than free space on the disk for example when copying on a floppy it will be split into several parts and the copying procedure will sequentially ask for the necessary number of removable disks 160 Backup data to archive Number o
165. e chapters Analysis Source distribution LORETA command and Analysis Spectra power distribution LORETA command The detail description of LORETA Low resolution electromagnetic tomography method can be found in R D Pasqual Marqui C M Michel D Lehmann Low resolution electromagnetic tomography A New Method for Localizing Electrical Activity in the Brain International Journal of Psychophysiology 1994 18 pp 49 65 Automated spikes detection and analysis The automated spike detection method uses both amplitude temporal parameters of waveforms and their spatial characteristics Many authors emphasized the amplitude temporal parameters of waveforms are necessary for development of effective spike detection methods 1 Gotman 7 Gloor P Automatic recognition and quantification of interictal epileptic activity in the human scalp EEG Electroenceph clin Neurophysiol 1976 Vol 41 P 513 529 2 Gotman J Wang LY State dependent spike detection concepts and preliminary results Electroenceph clin Neurophysiol 1991 Vol 79 P 11 19 3 P Y Ktonas Automated spike and sharp wave SSW detection In Methods of analysis of brain electrical and Magnetis signals EEG handbook revised series Vol 1 4 A S Gevins and A Remond Eds 1987 Elsevier Science Publishers B V 211 241 pp 5 P Van Hesse H Hallez B Vanrumste Y D Asseler P Boon Evaluation of temporal and spatial EEG spike detection algorithms From the other hand
166. e chosen only if it 1s installed on your computer WinEEG works Resource File Choose resource RES file for final report generation 269 Edit template Run MS Word application to modify empty final report 116 Video recorder parameters Video recoder parameters X Camera Video Input Device Pinnacle Dv Capture Video Input Video Composite Video compressor Microsott MPEG 4 Video Codec V1 Frames 25 per second Resolution 352 259 pixels Video format Video Source Audio Input Device Sounds Digital Audio Audio Source Audio compressor MPEG Layer 3 Would you to capture audio Additional camera Would you laike to capture video from additional camera Video Input Device EM aker WOM Video Capture Video Input Video Composite Video compressor Microsott MPEG 4 Video Codec v1 Frames per 25 per second Resolution 320 x 240 pixels Video format Video Source Video black length 900 The parameters of main and additional cameras can be specified using this dialog Video input device Select video capturing device Video input Select video input to which camera is connected Video compressor Select on line video compressor The compressors Microsoft MPEG 4 Video Codec V1 or Microsoft MPEG 4 Video Codec will be best for many system configurations We don t 270 re
167. e computation X Groups of trials Mame Labels Correct Incorrect Artefacts ODORE Group differences E 4 3 6 5 Choose Channel list Artifact processing Synchronisation Level 1 00 uy Stimulus Channels Stimulus B Thresholds tor channels Button channel Mo Subject responce processing Frequence Defined Epoch 200 ns Define Frequence 5 Hz c MM dre Iw Use as default Save 100 Cancel To calculate ERCoh additional information on stimuli presentation structure in each trial is used together with source data To group trials by stimuli types or by response task trial labels are used These parameters are defined beforehand when creating editing stimuli presentation protocols by means of PSYTASK program installed on the presenting computer Many fields of this dialog are similar to those of Parameters for Event Related Potential Computation dialog So only additional fields are described below Channel List 216 a list of channel pairs to be processed not more than 24 pairs Frequency This group defines harmonic signal frequency for which the EEG event related coherence will be calculated Epoch sets width of sliding window used for ERCoh calculation Frequency defines the harmonic 68 Wavelet Dec
168. e file was opened from the database the corresponding record is modified when saving the file If the file is new name is assigned to it automatically and a record 15 added to the database To save the latest changes in another file use the File Save As command Shortcuts Main Toolbar Keys CTRL S 15 File Save As command Save the active document in a new data file A Save As dialog appears to define the new file name 16 File Compress video files command Compress or recompress video files by selected method When you run this command a Video files compression dialog appears 17 File Export Data command Save the data in a format compatible with other applications If an EEG file is active an Export EEG Data dialog appears An EEG file can be converted into text ASCII format binary format European Data Format EDF or Universal Data Format UDF Russian extension of EDF format If an EEG spectra file 15 active an Export EEG Spectra dialog appears the screen An EEG spectra file can be converted into text ASCII format 110 If an EEG indices is active an Export EEG Indices dialog appears An EEG indices can be converted into text ASCII format If an ERP ERD file is active an Export ERP ERD dialog appears An ERP ERD file can be converted into text ASCII format Shortcut Main Toolbar EF 18 File Export EEG and Video EEG command Copy selected part of EEG record to
169. e interval from the trial beginning the synchronizing stimulus see above exceeds this value resulting trial will be shortened from 15 end Press Load button to read parameter values from a file 225 Press Save button to save current parameter values to a file 75 Parameters of independent component analysis ICA dialog Parameters of independent component analysis ICA X Channels Time interval From stimulus Begining of Trial From ms U 0 Frequency band From 0 fo Baseline correction To left from Begining of Trial Lenght ms 60 Add Delete Add all Delete 5 elect all Unselect all Current iberatian Cancel Channels Select the channels you wish to export ERP from Use Add Delete Select All and Deselect All buttons Groups Select the trial groups for which you wish to export ERP To select or to unselect all groups quickly use Select All and Deselect All buttons Time Interval Set the time interval you wish to export data for The following interval parameters need to be Set From sets the starting point You can start at the very beginning of the trial or at the moment when one of the stimuli 15 presented From ms sets the beginning of the interval to export in relation to the starting point To ms sets the end of the interval to export in relation to the starting point 226
170. e of the following values for the Channel parameter All Only EEG channels or Only Bio channels An EEG interval a trial 1s treated as artifact if an ERP absolute value for any channel and for any bin exceeds the threshold Calculate Differences of Waveforms check this option to calculate differential ERPs if Full EEG file with separate processing for each fragment time interval option is chosen Calculate Statistical Significance check this option to calculate statistical significance of ERP difference from baseline separately for each ERP or differential ERP and for each bin or for each pair of bins taken to calculate differential signal The Student criterion 15 used to estimate statistical significance 211 65 Parameters for Event Related Potential Computation dialog To calculate ERPs additional information on stimuli presentation structure in each trial 1s used together with source data To group trials by stimuli types or by response task trial labels are used These parameters are defined beforehand when creating editing stimuli presentation protocols by means of PSYTASK program installed on the presenting computer Groups Of Trials The table defines context names for trial groups Name fields and corresponding trial label lists Labels fields Up to 8 different trial groups can be defined For each trial group a label list 15 defined label values in list are separated by commas 1 2 5 9 The same trial label
171. e tet t utut etic deal seed ek let Saini 121 GO Recorduie Buck Committees s teet ti es 122 Recording Playback command ects oi du Ev tei iu 122 87 Recording Play Forward command 122 88 Recording Fast Forward 122 99 Analysis Final Report commu arid eee 1227 Sopa CONNAN esee ade desc an ete e ee ean uo EUR dasa ote e te Qaeda dose UT Qe do e Oe aou Mehsud 127 DT Analysis FAC MODDING A ea Dues uae uo UT RON ARRA 122 92 Analysis EEG durat 123 SANAS ELG SDOGIEQ s COMMON Oi oso usi 123 94 Analysis COP 124 UO ANQINSIS Density Array command usines ia RR dots tete aun b udo DAN E 124 96 Analysis Source distribution LORETA COMMANA ed t S de e eed east lide 124 97 Analysis Spectrum power distribution LORETA command eese eese 124 95 Analysis Dipole Source CBramEock command aic dete toti tud UR Ede aee ie ideis 124 99 Analysis NONNE Analysts cc COMMON isses sa dte e edite uota ie ds
172. e this command to choose or to modify montage for an EEG file Signals are always acquired and recorded in monopolar form relative to the electrodes connected to A and A2 connectors The bandwidth for acquisition and recording is maximally wide 0 15 70 Hz for Mitsar EEG 3 Remember that 0 15 Hz frequency corresponds to 1 0 sec time constant This recording method allows conversion of raw data to any mono or bipolar montage with any bandwidth during subsequent viewing and processing The Montage parameters dialog consisting of five tabs is displayed after calling this command Go from tab to tab to define the following montage parameters a Define a list of channels and their parameters such as gain bandwidth and baseline see Montage parameters Channels dialog b Define colors for displaying signals see Montage parameters Colors dialog Define the referents calculated if any Av AvL and see Montage parameters Referents dialog d Test whether channels are correctly defined or view another montage in list see Montage parameters View dialog You can also select a montage from the list saved in the montage list If a parameter set 1s expected to be used many times it would be better to define it in the montage list see Setup Montage List command Next time you D Attention Montage parameters set by this command are applied only to the active file and not 119 need only select it from
173. e value takes 4 bytes The data is recorded as Float follows lt gt lt S Co gt SiC lt S2C1 gt lt S2C2 gt lt gt where denotes the i th time readout and C means jth channel Data written to file 1s reformatted and filtered according to the montage parameters it is not raw data EDF European Data Format supported by a number of European and American vendors of computer encephalography Data written to the file is reformatted and filtered according to the montage parameters it is not raw data UDF Universal Data Format supported by leading vendors of computer 172 encephalography in Russia UDF is an extension for the EDF format Raw data 1s written to the file ANL Old ERP data format DAT Lexicor data format In this case the sampling rate can be changed according Lexicor the setting of field Sampling Rate data files File Define full path of the destination file for exporting data to Use the on the right of the name field to choose a drive and a folder 25 Export video EEG dialog Export video EEG Time interval Selection Fragment 06 08 23 7 C Full EEG Output data Raw EEG Filtered EEG Low cut 5 DC High cut Hz 70 Y Match Folder 0 100 ____ Cancel The following options allow you to specify how raw EEG and video EEG should be copied
174. e values of differences of corresponding spectra parameters and their significance level are placed in the cells of tables 90 Database Parameters Databases Of Raw Data dialog Database Of EEG Base Pathname Enter full path for EEG database or press button on the right of the name field to browse folders Database Of EEG Working Folder Enter full path for EEG working folder or press button on the right of the name field to browse drives and to select a folder Database Of Biofeedback Records Base Pathname Enter full path for biofeedback database or press button on the right of the name field to browse folders Database Of Biofeedback Records Working Folder Enter full path for biofeedback working folder or press button on the right of the name field to browse drives and to select a folder If there is no file or folder with the name you entered a new one will be created if possible when you press OK or Apply button 246 Database parameters 7 X Databases of raw data Databases of processing results Browser settings Database records search parameters Database of EEG Database pathname oe RR RF Working folder YD AM Database of biofeedback records Database pathname C Projects WinEEGVideo Release EFBBASE DBF Working folder C Projects WinE EG Video Release BFBDATAN
175. eans of Edit Paste command Use the File Save command to save newly calculated ERPs in the database Click right mouse button to show the popup menu If the cursor 15 placed on a graph then Add Map Add Label Copy Parameter Distribution Copy Channel and Copy Channel to Report commands will be available in the popup menu Use the Add Map command to add a map in the Formatted Page window mode Use Add Label command to add peak labels on the active group ERP curve Use Copy Parameter Distribution to place a string of voltages into clipboard for selected active group ERP curve and time sample SUD JeCct Name r4AY 126 3 51305 90452 oder ld ZH DUO a cu 20 42 47 9514 156 Use Copy Channel and Copy Channel to Report commands to place selected channel and group waveform into clipboard or final report 85 150 0 9 150 0 9 ARE 0 072 1 00000 ThA The map and dipole localization picture will added for selected time sample if monopolar montage was used 86 7 ICA Window The design of ICA window for spectra of EEG independent components 15 presented on following figure EJ EyeClose20s ica Power spectra of independent components of EEG for 914 observations 9 RRE 0 008 ECC 0 98337 OHS 585258 Componenti Variance 14 394 Co
176. ect group pairs Change graph scale Correct baseline Save components filter Save signal filter 104 For ERP Window Displays ERP graphs arranging channels in columns and averaging groups in rows Displays ERP graphs arranging channels in rows and averaging groups in columns Displays ERP maps arranging time intervals in columns and averaging groups in rows Displays ERP maps arranging time intervals in rows and averaging groups in columns Displays ERP graphs according to ERP Display Format you have chosen Displays average EEG bandpower graphs for wavelet ERP analysis Displays Time Frequency rasters for wavelet ERP analysis Selects channels to be displayed on graphs or maps Views the statistics for averaging of ERP and response reaction processing results Export parameters of task performance for single trials For pop up menu of ERP Window Adds an ERP map for selected active trial group Adds a peak label on the graph for selected active trial group Copy string of voltages of active ERP group for selected time sample into clipboard Copy channel waveform map and dipole picture for ERP group into clipboard Copy channel waveform map and dipole picture for ERP group into final report Runs LORETA application and store to it the corresponding to selected time point Runs BrainLock application and store to it the corresponding to selected time point Clear all pick labels
177. ed EEG de synchronization It uses filters with finite impulse response FIR They provide significant signal suppression outside the bandwidth of interest and do not shift signal phase Filter parameters can be set by means of the Setup EEG Bandranges command The disadvantage of these filters 15 that they take a long time for calculations so they can not be used for real time EEG acquisition Electrooculographic artifacts correction The method of electrooculographic artifacts correction based on linear regression method in the time domain It is very helpful if there are many artifacts related eyes blinks To use this method an additional signal electrooculogram should be recorded The electrooculogram EOG is recorded using two additional electrodes placed higher and below eye and connected to additional EEG channels for example Fpz and Oz sockets In this case a montage should include one additional bipolar channel Fpz Oz During the processing WinEEG program using threshold criteria will automatically detect time intervals in which eye blinks were observed Using this data WinEEG program calculates coefficient of influence 33 of EOG for each EEG channel separately Finally WinEEG program subtracts EOG signal multiplied in corresponding coefficient from EEG signal This correction procedure can be performed using Analysis Remove EOG command Attention The quality of work of this correction procedure depends on quality if EOG
178. ef F8 Ref 100 Normoliealion T3Ref T4 Ref TRRef Lhannel fA Deta O O Afs 0 Detal 0 Deta 0 Gomme O O O L1 D O O O O switch between window modes use the following Analysis menu commands EEG Spectra Displays EEG power spectra autocorrelation Coherence for Displays EEG coherence cross correlation for a Channels selected channel Average Coherence Displays average EEG coherence for all channels Disabled for auto and cross correlation Phase Spectra Displays EEG phase spectra for a selected channel Disabled for auto and cross correlation Bispectra Displays EEG bi spectra frequency frequency plots Disabled for auto and cross correlation Bicoherence Displays EEG bi coherence frequency frequency plots Disabled for auto and cross correlation If spectral dynamics have been calculated during EEG processing you can toggle between Average Spectra and Spectral Dynamics window modes see Analysis menu commands Disabled for auto and cross correlation Use the Scale list or and keys to change color scale sensitivity or Y axis scale for graphs Use the Value list disabled for auto and cross correlation to choose what value to depict in graphs and maps P uV 2 Graphs Y axis shows signal power Color scale encodes power 1n regular intervals Measurement units squared microvolt T1 A uV Graphs Y axis shows
179. egistered channels list of displayed channels and their parameters gains bandwidths baselines colors etc Remember that signals are acquired and recorded always in monopolar form referenced to the electrode connected with A1 and A2 nets The bandwidth for acquisition and recording is maximally wide 0 15 70 Hz for Mizar EEG 3 Remember that 0 15 Hz frequency corresponds to 1 0 sec time constant This recording method allows conversion of raw data to any mono or bipolar montage with any bandwidth during subsequent viewing and processing Note After recording EEG data the phrase any bandwidth must be understood to mean any bandwidth that 1s less than or equal to the instrument s maximum bandwidth 1 e 70Hz in the case of the Mitsar EEG 3 A Montage parameters dialog consisting of six tabs 1s displayed after calling this command Go from tab to tab to define the following montage parameters a Define a list of channels for EEG acquisition corresponding to electrodes actually placed and connected see Montage parameters Electrodes dialog Also define coordinates of the electrodes b Define a list of channels in the montage and their parameters such as gain bandwidth and base line see Montage parameters Channels dialog c Define colors for displaying each channel see Montage parameters Colors dialog d Define the calculated referents if there are any e g Av AvL and AvR see Montage parameters Referen
180. elected interval by 60 mm Calibration style Choose an option defining how to print calibration Line width for EEG window Choose an option defining line width for printing EEG waveforms 100 Colors dialog To choose a color click the corresponding button 101 Mapping parameters dialog Palette Choose a color palette from the list The palette encodes values displayed on the maps by color Mapping style Interpolation method Palette f Spherical splines Barycentric Red 255 Greer 0 E Blue 255 Interpolation order 2 C Drak Show electrode position Draw isopotential contours Cancel 258 Slider Use the slider placed to the right of the color scale to choose a color for modification Red Set a value for the red component of the selected palette color Green Set a value for the green component of the selected palette color Blue Set a value for the blue component of the selected palette color Interpolation Method Choose an interpolation method Spherical splines are recommended but barycentric interpolation is better if few electrodes are used Interpolation Order Set interpolation order recommended value 15 2 Quality This parameter defines pixel size for the maps Best option is recommended meaning the smallest pixel size If you choose Draft maps will be painted about three times faster Show electrode position Check 1 electrode posi
181. election Process interval between two vertical markers Fragment Process fragment selected from the list Full EEG file Process the whole file Epoch Length Select epoch length for analysis Spectrum step 1s derived from epoch length second Hz spectrum step 2 seconds 0 5 Hz spectrum step 4 seconds 0 25 Hz spectrum step 8 seconds 0 125 Hz spectrum step 16 seconds 0 0625 Hz spectrum step 32 seconds 0 03125 Hz spectrum step 64 0 015625 Hz spectrum step 222 50 Choose this option if a non square time window 15 used None Choose this option if a square time window 15 used Time window Choose time window type Time windows are used to suppress side lobe infiltration by smoothing a source realization epoch to decrease sharp variations in its initial and final intervals Square wij 1 Bartlett w j 1 abs j 0 5 N 0 5 Hanning wij 0 5 1 c0s 6 28 N Welch wij 1 j 0 5 N 05 N 4 0 5 N 0 5 Upper spectra frequency Choose upper spectra frequency their length Artifact elimination Check options to define types of artifacts to be eliminated Polynomial trends Polynomial trend is estimated for each epoch and each channel and eliminated from source signal Additional parameter polynomial order Slow waves Epochs with too large slow wave signal component cause by eye motion or other artifact are eliminated from averaging Additional parameters maximal
182. elet bandpower analvsis functional diagram Select T Wavelet wavelet bandpower a 868 bandpower time mitervalz over defined dk le for a number frequency each tiles of trial groups band time interval Compute Concatenate Decompose average i i tune mtervals from different independent of files components independent components ERD database records 7 selection ICA window Computing and analysis grand average independent components ERD for wavelet band power 53 Video EEG recording WinEEG program provides the next features for Video EEG recording 1 Synchronous on line recording of EEG video signals from one or two cameras and audio signal from microphone 2 On line and off line compression recompression of video and audio signal MPEG4 compression of video signal and MPEG3 compression of audio signal are provided Night video monitoring using video camera with infrared illuminant Manual marking of events during EEG and video recording Off line synchronous playback of EEG video and audio signals Automatic positioning to video pictures corresponding to manually selected EEG sample or marker 7 Editing of EEG video and audio signals to save meaningful fragments only 8 Advanced service for preparation of CD copy of video EEG record 9 Compact but powerful free video EEG viewer for displaying of CD or DVD copy of video EEG record provides next
183. els bandranges corresponds to an EEG frequency band Delta Theta etc Bispectra for defined Writes the table of EEG bispectral parameters to an ASCII file 175 bandrange Columns present channels corresponding to each pair of EEG frequency band Delta Theta etc Bicoherence for Writes the table of EEG bicoherence parameters to an ASCII file defined bandrange Columns present channels corresponding to each pair of EEG frequency band Delta Theta etc Bandrange list Choose what frequency band list will be used see Setup EEG bandranges command Values Choose what values to export Power P absolute power values Amplitude A square root of absolute power values Percentage frequency band power as a percentage of total power Coherence and Phase Coherence the coherence or average coherence for defined frequency band will be exported together with power spectra Phase the phase spectra or average phase for defined frequency band will be exported together with power spectra Bandranges In Row Check this option to arrange spectral parameters for each channel in a single line Otherwise they will be written in several lines Include Column Names Check this option to add column names in the first row of the file Column names can be useful for example for data exported to Statistica software Include Row Names Check this option to add row names in the first column of the file Row names c
184. ependent component similarly described above ERPs calculation Chapter 15 15 Single trials component waveforms average component ERPs and component topographies are displayed in ICA window and are available for analysis Following diagram illustrates consequence of processing and analysis steps 49 ICA single trial ERP analvsis functional diagram Spatial High order Montage filtering Bandpass a a T x Li l processing artifacts filtermg FIR filtering correction 5 EEG datafile Calibration NOM Select Correct Concatenate Decompose Compute Artifacts single baseline single independent to elimination trial for each trial independent components epochs epoch epochs components ERP Database of observations ICA window Computing and analysis independent components ERP The command Independent component ERP from menu Analysis runs this procedure 3 The grand average spectra of EEG independent components The spectra of EEG independent components are computed for selected in EEG database collection of EEG recordings Additional assumption is also suggested that cortical localization of components 15 similar between subjects so that it is viable to implement the ICA on array of EEGs The ICA decomposition of the array of individual EEGs was performed as follows Several seconds epochs defined as parameter of processing of artifact free multi channel EEG recording of each subject were merged into
185. erage ERP and grand average ERD for selected set of observation To perform grand averaging open corresponding database select subset of records and press button Average Attention The compatible data only can be used for grand average computation This means the montage and processing parameters should be the same for all averaging spectra ERPs or ERDs The WinEEG program can perform batch data processing It helps to process large amount of data automatically This could be artifacts correction artifacts detection EEG filtering computation EEG power spectra and coherence ERP ERD wavelet analysis and wavelet coherence The results of processing can be saved to source EEG data files and to new processing results data files in dependence on settings The power spectra and coherence ERP ERD wavelet decomposition and wavelet coherence are saved in corresponding databases of processing results The processing report could be generate automatically and could be used for detection of processing mistakes To start batch data processing open EEG database select subset of records and press button Average Following diagram illustrates automatic EEG batch processing steps 55 Batch processing functional diagram Update montage Op and bandpass filters EEG datafile Calibration arameters EEG database List of selected EEG recordings Compute spectra and coherence Save spectra datafile Save FEG
186. ers Database Of Event Related Coherence ERCoh Working Folder Enter full path for ERCoh working folder or press button on the right of the name field to browse drives and select a folder Database Of EEG Cross correlation Database Pathname Enter full path for EEG cross correlation database or press button to the right of the name field to browse folders Database Of EEG Cross correlation Working Folder 248 Enter full path for EEG cross correlation working folder or press button to the right of the name field to browse drives and to select a folder If there 1s no file or folder with the name you entered a new one will be created if possible when you press the OK or Apply button 92 Database Parameters Browser Settings dialog This dialog defines fields for Record List dialog Field Check those fields you wish to use in the record list Width Set width in pixels for each field used in the record list Database parameters X Databases of raw data Databases of processing results Browser settings Database records search parameters Position Field Position ID 1 Diagnosis 7 Date 2 Birthdate Time 3 Sex 30 3 Investigation 4 Address 400 10 w Patient name Note 11 Patient ID m Position Set position ordinal number for each field used in the record list 93 Database Parameters Base Re
187. esentation Program command 8 Use the Recording Pause command to temporary stop EEG recording and stimuli presentation if it is necessary Use Recording EEG Monitoring command to continue EEG recording and stimuli presentation 9 Stop EEG acquisition using the Recording Stop command 10 Save the newly created EEG file into the database using the File Save command 11 Remove the electrodes and let the patient go 44 D Attention To avoid data loss do not carry out Step 11 before Step 10 12 Analyze the newly recorded EEG using commands Analysis Compute ERP command Analysis Compute ERD command Analysis Compute ERCoh command Analysis Compute Wavelet command omission and commission errors the signal from special micro switch should be recorded To do this 1 Connect micro switch to ECG socket or to digital inputs socket in dependence on type of EEG amplifiers 2 Add ECG channel to montage planed to use if ECG socket is used 3 Don t forget to define the parameters of processing of button signal t Attention If it is necessary to study subject reaction time and task performance parameters Computing and analysis of ERP ERD ERCoh To compute and analyze ERP ERD ERCoh or Wavelet three steps should be performed 1 Manual or automatic artifact rejection 2 Computing the ERP ERD ERCoh or Wavelet using Parameters for Event Related Potential Computation Parameters for Event
188. et new graphic page size The Page Size dialog is displayed after calling this command After setting new size horizontal and vertical sizes and positions of graphs would be proportionally modified Axes Customize axes output Check axes to be displayed X and or Y and set values for tic mark step milliseconds for X micro Volts for Y Calibration Customize calibration scale output position on the page in relation to left upper corner and size Waveform graphic line parameters for groups Choose color and style for ERP graph lines for each trial group up to four groups can be depicted on a page simultaneously see ERP window Press a color filled button to call Colors dialog Press a button with a horizontal line to call Line Style dialog Table of Graph Parameters Each row of the table displays parameters for one graph position in relation to upper left page corner horizontal and vertical size and list of depicted curves One graph can depict up to four 264 curves corresponding to different trial groups for only one channel Besides under graph there can be histograms for each of four trial groups encoding results of ERP statistical analysis see ERP window For example if Curves List field contains the following Gr14St lt Gr2 lt Gr3 lt Gr4 gt The graph will depict ERPs for F3 channel and for four trial groups named by means of Averaging Groups bar Also a histogram of statistical significa
189. eys CTRL O 3 File Open Another Database gt EEG Spectra command This command opens an EEG spectra file from the database in a new window You can open several EEG spectra files simultaneously Use the Window menu commands to switch between opened files See Window 1 2 command As you run this command a Record List dialog is displayed for searching EEG spectra files in the database or in the archive 4 File Open Another Database gt EEG Cross correlations command This command opens an EEG auto and cross correlation file from the database in a new window You can open several EEG auto and cross correlation files simultaneously Use the Window menu commands to switch between opened files See Window 1 2 command As you run this command a Record List Dialog is displayed for searching EEG auto and cross correlation files in the database or in the archive 5 File Open Another Database gt EEG Indices command This command opens an EEG indices file from the database in a new window You can open several EEG indices files simultaneously Use the Window menu commands to switch between opened files See Window 1 2 command As you run this command a Record List Dialog is displayed for searching EEG indices files in the database or in the archive 6 File Open Another Database gt EP File command This command opens an event related potential evoked potential file from the database in a new window You can o
190. f ERP processing parameters saved in the files into WinEEG ERPPARAM folder and corresponding to each example of task included in PSYTASK program P300 PAR for Odd ball task Go_NoGo RAP for Go NoGo task TOVA PAR for TOVA task PAT_H PAR PAT HLR PAR PAT LR PAR for Reversionary pattern tasks The parameters of computation of ERD ERCoh and Wavelet are the similar Analysis of EEG independent components and ERP independent components A common view of EEG and ERP components recorded from the scalp 15 that they are a superposition of several signals from sites placed inside the brain Many attempts of localization of these sources were made at different scientific laboratories in the world The results of this studies is the development very effective methods of localization of equivalent brain sources thus as dipole source localization low resolution electro magnetic tomography and etc This studies display some problems that should be solved to increase the accuracy of localization of brain sources 50 in the case of equivalent dipole sources localization the number of dipoles 15 a priori unknown One of solution of this problem is to decompose raw multi channel EEG to a number of components using information about interaction of signals recorded from different sites and localize equivalent sources for resulting components separately The additional suggestion 15 usually any independence of these components Assumptions that un
191. f Files 1 Total Size 18 69 Mb Volume DISKI Remove files from working folder Please don t forgen to write a volume name to label of removable disk It will be helpfull when will search nessesary data in the Future 0 100 Cancel Attention Use Restore command to restore a backed up file into database working directory Using a file Copy procedure to move data in the archive can change format of the data file Drive select drive to backup the data file to Check Remove Files From Working Folder option to delete the backed up file s from the working directory 13 Archive Data dialog To restore an archive file means to copy a backed up archived file corresponding to the selected record from the specified disk to the working directory see Data Archiving If the data file 15 archived on several floppies they will be asked for sequentially Restore archived data Volume label 100 mn Drive select drive to restore data file from 14 Delete Data From Database dialog Be careful when running this command mistake can lead to unrecoverable loss of important data First of all define what exactly 1s to be deleted 161 Delete data from Database X C Data file and corresponding record Cancel Only Data File option would be usually chosen to free hard disk space but only if the file has been
192. factorizes p u The data submitted to ICA are simply the recorded EEG channel data arranged in a matrix of n channels rows by t time points columns No channel location information at all 1s used in the analysis ICA performs a blind separation of the data matrix X based only on the criterion that resulting source time courses U are maximally independent Specifically ICA finds a component unmixing matrix W that when multiplied by the original data X yields the matrix U of independent component IC time courses Each column of the W mixing matrix represents the relative projection weight at each electrode of a single component source IC topography Mapping these weights to corresponding electrodes on a cartoon head model allows visualization of the scalp projection or scalp map of each source The source locations of the components are presumed to be stationary for the duration of the training data That 1s the brain source locations and projection maps are assumed to be spatially fixed while their activations U reveal their activity time courses throughout the input data Thus the IC activations U can be regarded as the EEG waveforms of single sources although obtaining their actual amplitudes at the scalp channels requires multiplication by the inverse of the unmixing matrix The back projected ICs X are 1n the same mV units as the recorded scalp data However neither the IC sc
193. ferent montage from the list for use as a new default You can also rename the selected montage Channel List The table of channels in the montage is placed on the left side Each row corresponds to a channel in the montage don t confuse them with the channels in the acquisition list The montage channel list includes channels that will be displayed during the monitoring and processed Columns correspond to channel parameters a The No column contains the ordinal number of the channel To the left of it there 15 a pictogram its color 15 the same that the waveform color in the EEG window It depicts also the channel status visible or hidden if the pictogram is marked by a V character the channel is shown in the EEG window visible otherwise the channel is not displayed hidden AII channels included in the list of montage channels will be used for processing except universal channels Biol 102 145 The Channel column shows electrode scheme for example 2 electrode named first 1 the active one and the second is the passive one A channel can be used if it 15 included in the list of monitored channels b The Gain column shows the channel gains For any channel in the montage you can select a gain value from list 1 0 1 5 2 0 3 0 5 0 7 0 10 0 15 0 20 0 30 0 50 0 70 0 100 0 150 0 200 0 300 0 500 0 700 0 uV cm 1 0 1 5 2 0 3 0 5 0 7 0 10 0 15 0 20 0 30 0
194. for analysis of EEG coherence because 198 Epoch number Specify number of epoch for averaging Channels Define a sunset of channels to be processed Epoch Length Select epoch length for analysis Spectrum step 1s derived from epoch length second Hz spectrum step 2 seconds 0 5 Hz spectrum step 4 seconds 0 25 Hz spectrum step 8 seconds 0 125 Hz spectrum step 16 seconds 0 0625 Hz spectrum step 32 seconds 0 03125 Hz spectrum step 64 0 015625 Hz spectrum step Overlapping 50 Choose this option if a non square time window 15 used None Choose this option if a square time window 1s used Time window Choose time window type Time windows are used to suppress side lobe infiltration by smoothing a source realization epoch to decrease sharp variations in its initial and final intervals Square wij 1 Bartlett w j 1 abs j 0 5 N 0 5 Hanning wij 0 5 1 c0s 6 28 N Welch wij 1 j 0 5 N 05 N 4 0 5 N 0 5 Upper spectra frequency Choose upper spectra frequency their length Artifact elimination Check options to define types of artifacts to be eliminated Polynomial trends Polynomial trend is estimated for each epoch and each channel and eliminated from source signal Additional parameter polynomial order Slow waves Epochs with too large slow wave signal component cause by eye motion or other artifact are eliminated from averaging Additional parameters maximal
195. fragment selected from the list Whole EEG file Process the whole file First word delimiter Use this list to select delimiter of first word in fragment name This option is very useful if EEG recordings have different names of fragments but there is a common part at the beginning of one Beginning interval length Define maximal duration of artifact free EEG record for each selected file included in estimation of component topographies matrix see above This parameter should not be very large because computational time and computer memory consumption problems can occur Epoch Length Select epoch length for analysis Spectrum step 1s derived from epoch length second Hz spectrum step 2 seconds 0 5 Hz spectrum step 4 seconds 0 25 Hz spectrum step 8 seconds 0 125 Hz spectrum step 16 seconds 0 0625 Hz spectrum step 32 seconds 0 03125 Hz spectrum step 64 0 015625 Hz spectrum step Overlapping 50 Choose this option if a non square time window 15 used None Choose this option if a square time window 1s used Time window Choose time window type Time windows are used to suppress side lobe infiltration by smoothing a source realization epoch to decrease sharp variations in its initial and final intervals Square wij 1 Bartlett w j 1 abs j 0 5 N 0 5 Hanning w j 0 5 1 c0s 6 28 N Welch wij 1 j 0 5 N 05 N 4 0 5 N 0 5 Upper spectra frequency Choose upper spectra frequenc
196. g this command you have a risk to loss the data That is why the usage of 8 Choosing a channel to be processed To choose a channel press the corresponding button on the Channel Names bar You can also choose channels using Arrow Up and Arrow Down keys For more detailed view of a single channel use one channel display mode To toggle between one channel and multi channel modes place cursor on a button on the Channel Names bar or on the corresponding EEG curve and double click left mouse button 9 Comparing EEG for different channels To compare EEG recorded from different sites you can place one curve over another while viewing Place cursor on a button on the Channel Names bar and drag vertically with left mouse button pressed The curve depicting the selected channel also will move in the vertical direction When left mouse button 15 released the selected curve automatically returns to its original position 10 Measuring channel parameters Channel parameters are measured automatically and displayed in the status bar fields Note that all parameters are not always measured The selected interval see 8 above should be 100msec 10sec long and visible in the EEG window The following parameters are computed automatically EEG value at the left marker L 0 1 uV EEG value at the right marker R 0 1 uV Time interval between two markers 0 1 sec Difference between EEG values at the two markers R L 0 1 uV E
197. gether with new portion of data in this case The data can be recovered in this case if a crash of WinEEG program or Microsoft Windows have occurred Do not redraw EEG window after sensitivity changing faster Check this button if you would like to do not redraw whole EEG window when vertical scale is changed Only newly recorded samples will be displayed using new vertical scale this case This is fastest mode of work Use it if some problems with the acquisition errors on slow computers occur 96 Preferences EEG Window dialog Colors List of window elements displayed in color Under the list there 15 a button showing current color for the selected element Click it to call Colors dialog and to modify element color Grid Choose vertical grid style for EEG window and also for printing None No grid 1s shown or printed 1 second step Coarse grid 1 second step 200 millisecond Fine grid 200 millisecond step step Preferences EEG input EEG window Scale Printing Colors Background Grid Baselines Waveforms Active channel Color labels Test labels Time scale Time scale text Selected time scale Grid C None 1 second step 200 milisecond step Show Channel base lines w Calibration in channel names W User labels Show 253 a T m M oe ii Ampy Help Check additional graphical elements to be shown in EEG window Horizonta
198. graphy templates More information concerning this method can be found at Jung T Makeig S Humphries C Lee T McKeown M Iragui V and Sejnowski T Removing electroencephalographic artifacts by blind source separation Psychophysiol 2000 V 37 163 178 It should be emphasized that the quality of artifact signal correction depends on a possibility to separate the blind source signals related to the artifacts Theoretically the artifact related signals usually correlate with brain signals As results there is no way to separate pure artifact related components That is why some EEG signals will be suppressed also by this method Our studies are shown that this method will suppress EEG and ERP signals for the frontal recording sites Fpl and Fp2 channels to a marked degree These studies are shown that ICA method will give smaller signal distortions in comparison with PCA method interval used for estimation of spatial filter matrix That is why the visual inspection should be done after performing this procedure If the results of artifact correction are not satisfactory another time interval should be selected for analysis Attention The quality of work of this correction procedure depends on selection of time Automatic and manual artifacts elimination WinEEG program includes different artifacts detection procedures The simplest way is a visual inspection of EEG record and marking or removing the time intervals including a
199. h the Setup program WARNING This program is protected by copyright lav and International treaties Unauthorized reproduction or distribution of this program or any portion of it may result in severe civil and criminal penalties and will be prosecuted to the maximum extent possible under law Cancel 6 Press Next button to continue installation 12 Choose Destination Location x Setup will install WinEEG in the following folder To install to this folder click Next install to different folder click Browse and select another folder can choose not to install WinEEG by clicking Cancel to exit Setup Destination Folder C MitsarsyinEEG Browse 7 Press Browse button if you would like to change location WinEEG program Press Next button to continue installation Setup Click the of Setup you prefer then click Next Typical Program will be installed with the most common options Recommended for most users Compact Frogram will be installed with minimum required options C Custom You may choose the options you want to install Recommended for advanced users lt Back Cancel 8 Select type of Setup you prefer Press Next button to continue installation If Custom installation 1s selected following window will appear on the screen 13 Select Components x Select the components you want to install clear
200. hard Turn On Off Calibration EEG Recording on off Pause Stop Video Recording Reset DC Filter Photostimulation on off Photostimulation Program Stimuli Presentation Program Turn on off Music Calibration Impedance Rewind Back Play Back Play Forward Rewind Forward Analysis Menu Commands 102 disk Turns on off calibrating signal Starts recording a new EEG fragment to the hard disk Pauses EEG acquisition Stops EEG acquisition and switches to signal view mode Start stop recording of video data Use this command to reset constant component of the signal Turns photo stimulator on off Starts a photo stimulation program Starts presenting stimuli for ERP acquisition Turns on off music for auditory biofeedback Checks calibration of the amplifiers Enables automatic measurement of electrode impedance Rewinds the EEG window left Plays back the EEG window left Plays back the EEG window right Rewinds the EEG window right The Analysis menu offers the following commands Final Report Insert Patient Card Insert Final Report Template Signal Parameters EEG Mapping EEG Indices EEG Spectra EEG Cross correlations Spectra Density Array Source distribution LORETA Spectra power distribution LORETA Dipole Source BrainLock Nonlinear Analysis Spike Detection Spike Averaging Remove EOG Mark artifacts Artifacts correction Artifacts correction template
201. his command to calculate coefficients for electro oculogram influence on EEG and to subtract weighted EOG signal from signals of other channels One of the EOG Rejection dialog will be displayed on calling this command EOG was recorded at least by one channel It also assumes that no other high amplitude artifact occurred during EEG acquisition Otherwise EEG can be significantly distorted and eye movement artifact elimination may be quite poor D Attention The algorithm of EOG artifact elimination is not ideal and supposes that a pure Shortcut Main toolbar 103 Analysis Mark artifacts command Run this command to automatically detect artifacts parts of EEG record based on threshold criteria and to mark corresponding time intervals One of the Search and rejection artifacts dialog will be displayed on calling this command Shortcut Main toolbar 104 Analysis Artifacts correction command Run this command to calculate spatial filter matrix that 1s used to correct EEG artifacts The selected part of EEG record is used to estimate EEG and artifact components of record by PCA or ICA methods The artifacts components are selected manually by visual inspection of their topography Using these data the corresponding spatial filter 15 computed The Artifacts space filtering parameters estimation dialog will be displayed on calling this command Run this command again to disable previously activated artifacts correction
202. ial in according with parameters of subject response processing or zero if this trial does not belong to averaging group 134 6 Columns include number of second button presses during the trial in according with parameters of subject response processing or zero if this trial does not belong to averaging group 151 Pop up menu of ERP window Add Map command Add a map in ERP window The map is added for active trial group see Averaging Groups Bar and for the time readout bin marked on the ERP graph by the by cursor position when holding the right mouse button pressed 152 Pop up menu of ERP window Add Label command Add a peak label on a graph in an ERP window Peak label is added for active trial group see Averaging Groups Bar and for time readout bin marked on the ERP graph by the by cursor position when holding the right mouse button pressed Before the first call of the LORETA application the WinEEG program ask for a location of LORETA EXE file Its usual location is folder with name LORETA 020 MAIN 153 Pop up menu of ERP window Copy Parameter Distribution command Copy string of voltages of active ERP group for selected time sample into clipboard 154 Pop up menu of ERP window Copy Channel command Copy channel s waveform map and dipole picture for active ERP group into clipboard The map and dipole picture will correspond to time sample selected by mouse pointer 155 Pop up menu of ERP window C
203. ial group pairs for calculating differential ERPs Group pairs are separated by commas Group numbers in a pair are separated by a hyphen a minus sign Press Choose button to choose group pairs see Choose Group Differences dialog Artifact Processing The following parameters are used for automatic artifact analysis and elimination Level set threshold value 1n uV An EEG interval a trial 1s treated as artifact 1f an ERP absolute value for any channel and for any bin exceeds Level value Channels define channels to be processed for artifact analysis Possible options are All process all channels Only EEG process only EEG channels Only Bio process only Bio channels Table the defined channel table 1s used and Level value is ignored Don t Reject artifacts are not eliminated Use the Threshold for channels button to define a list of channels to be processed and individual threshold values for artifact analysis This button calls Artifact Rejection Thresholds dialog Synchronization Several stimuli are allowed to be presented during one trial Also pre and poststimulus intervals may change from trial to trial even if trials belong to one averaging group In this case it 1s necessary to set additional parameters to synchronize trials correctly when averaging them Moreover some tasks may need analyzing ERPs preceding the response reaction Type select trial synchronization type Stimulus standard trial synchroni
204. independent storages see figure 6 Each of storages consist of processing results database file the list of records and corresponding working folder using for writing processing result files 30 Quick Start The following steps describe briefly how to acquire an EEG and to create a final report 1 Place the electrodes on the patient s head For a normal investigation 19 electrodes are placed using the International 10 20 system Also a common point electrode N electrode and reference electrodes must be placed Attention Common point and reference electrodes are to be placed in any case whether A bipolar or monopolar montage is used If EEG is assumed to be recorded in reference to ears two reference electrodes are placed on the ears A reference electrode can be placed on the forehead and connected to Al or A2 input the appropriate electrode is provided in the set and a corresponding montage 15 set in the program EEG signal quality depends on paying special attention to the placement of common point and reference electrodes 2 Connect the electrodes to their respective inputs on the front panel of the amplifier block 3 Set the electrode impedance checking mode using Recording Impedance command If the impedance value is satisfactory less than 5 kOhm close the Control of Electrode Impedance dialog Otherwise re install electrodes showing excessive impedance 4 Run the File New command Fill in the p
205. ing from archive to the working directory Restore Archive Data dialog appears then Report button calls the function that creates The databases of results of processing can have additional buttons So Database of evoked potentials has two additional buttons a statistical report including quantity EEG observations carried out during selected time interval and or with different groups of subjects and insert resulting table into MS Word The Statistical results dialog appears then Database of EEG recordings NET 59 2 HMT 59 4 6 59 18 2 01SM 5 3 2 HI 18 Moca THMT H0 19 2 19 BUE 24M 032M Hi HI Ma ID naca HMT 20 03 2007 16 04 2008 1 E is 13 04 2007 16 05 2007 26 12 2006 B Db DET i Beng AUT 272006 20 12 2006 Date 29712 2006 24 02 1968 16 10 1999 07 03 1989 18 05 1987 14 03 1989 21 11 1988 30 08 1988 26 06 1971 IS le 07 06 1967 04 09 1988 18 08 1982 27 101974
206. ing procedure 231 80 Parameters of averaging groups dialog Parameters of averaging groups Display group Trial number Total BBD jaaGo eo JapNoGO Ix LM M M M M z Cancel This dialog window allows select a list of groups for displaying them in ICA window The additional possibility is to define colors and line style for graphics Finally there is a possibility to rearrange the data and define new averaging groups The new group names and trial number should be defined of trials in the file D Attention The sum of trials for all newly defined groups should be equals the total number 232 81 Select averaging groups for displaying dialog Select group pairs Ix This dialog window allows select a list of groups for displaying them in ICA window The additional possibility 1s to define colors and line style for graphics 82 Define graphs scale dialog Define graphs scale x Graphs vertical scale t Different for each graph default f Common defined by value 3 Graphe horizontal scale f Whole waveform C Only defined beginning interval m 1 100 Cancel By default independent components graphs have individual vertical scale This dialog allows define common scale for all graphs with specific value Graphs vertical
207. ing the Find what one 185 39 Find Events Findevents x Do Find next Threshold 100 Cancel Channel The following options allow you to specify parameters of searching Events when the absolute voltage of EEG signal is higher then defined threshold If selected channel is digital channel the voltage threshold is not used Channel Select processed channel Threshold Select voltage threshold Find Next Find next time interval of EEG record when absolute voltage of EEG signal of selected channel was higher then defined threshold and display EEG waveforms in EEG window 40 Replace dialog Find What Define the string to be searched for Replace With Define the string to replace the one found Replace Find what with Match whale ward only Cancel Match case Match Whole Word Only Check to find only whole words matching the Find What string Match Case Extend search criteria to include uppercase and lowercase attributes while searching for the Find What string in the text Find Next Find next string matching the Find what one Replace Replaces the string found and resumes searching 186 Replace Finds and replaces all strings that match the Find What string 4I Patient Card dialog Fill or edit the patient card Patient Card X ID Date 3170172008 Time 030
208. ion ERPs as a source data The parts of ERP waveforms corresponding to specified time intervals are merged to continuous time series and than this data are decomposed to independent components Grand average ERPs are computed separately for each independent component Individual ERP component waveforms grand average ERP components and component topographies are displayed in ICA window and are available for analysis Additional assumption is also suggested that cortical localization of components is similar between subjects so that it is viable to implement the ICA on array of ERPs Following diagram illustrates consequence of processing and analysis steps 51 ICA average ERP analysis functional diagram EL Correct Concatenate ERP files esie baseline time intervals pe NS for each from different for a number pin of trial zroups files Compute Decompose grand average to independent ERPs of components independent components ERP database records TE selection xim window Computing and analysis grand average independent components ERP This procedure is run by pressing button ICA in Database dialog window for ERP database see below 5 The grand average ERD and wavelet band power of independent components Formally similar procedure see previous chapter can be applied for ERD waveforms But it should be stressed here that assumption Summation of the electric currents induced by separate
209. ion for printing EEG spectra Paper orientation for indices window Choose paper orientation for printing EEG indices Paper orientation for ERP ERD window Choose paper orientation for printing ERP ERD and ERCoh Paper orientation for biofeedback window Choose paper orientation for printing biofeedback window contents Preferences EEG input EEG window Scale Signals polarity Printing Paper orientation Far EEG window Printing Default Portrait I Channel names Iw Calibration Paper onentation EEG mapping window Default Portrait Landscape Using memory buffer Calibration style Paper onentation for spectra window Default Portrait Landscape Value only Paper orientation for indeces window Values and vertical bar C Default Portrait Landscape Values and calibration signal Paper arientation EER window Line width for EEG window Default Portrait Landscape f Thin Middle Paper onentation biofeedback window Thick C Default Portrait Landscape Printing Check options for graphic elements to be printed together with EEG Channel names Check this to print channel names left of each page 231 Calibration Check this to print conventional calibration signals showing gains and bandwidths for EEG channels If this option is checked calibration will be printed on the last page increasing s
210. ion functional diagram Spatial High order ppc Y Montage filtering Bandpass bs seach o 1 andpass EEG datafile Calibration processing artifacts filtering 2106 i spike like NOE correction filtering wavetorms Array of parameters of spike like waveforms Database of observations Automatic spike detection 59 Warranties Of course WinEEG may have its own bugs as any other software We apologize in advance for possible troubles and promise to do our best to find and correct software errors hoping that you would meet them not very often If you detect any discrepancy between the manual and the real performance of the software please do not hesitate to contact the developers directly You can always learn the contact information using the Help About WinEEG command Quick and effective troubleshooting is our duty and we shall be grateful for your help in detecting any bugs You will receive a free revised software version on your request Extending the WinEEG vocabulary of software features 15 another question WinEEG 15 a commercial product so the developers follow industry practices and deliver the product as 15 Your comments the product features will be gratefully accepted and probably be taken into account when developing further software versions But we cannot guarantee immediate addition of new features requested by our users Naturally we will meet the wishes of any customer who
211. isk of PC for the future processing WinEEG receives synchronously the signals from cameras and microphone compress these signals on line and stores them to hard disk for future playback and analysis During the work WinEEG and PSYTASK interact with OS and different external modules and drivers see figure below 26 Video Card driver Audio Card Monitor Card Monitor Pus Mitsar driver Video driver stimulator Amplifiers driver Audio ard Windows and MEC driver Windows and MEC Patient s warning button Direct Keyboard Sound Direct Sound COM COM WinEEG Mouse Printer driver Audio card Compressor t driver PSYTASK capture Direct Compressor Show card driver Video capture card driver Direct 1 Compressor Show Microphone Second video camera Video out Guardant driver Second video camera Video out Diagram of interaction of WinEEG and PSYTASK software with different external modules and drivers 27 Main Functions 1 EEG Recording During recording EEG and other signals are acquired in digital form by the computer through amplifier block and displayed on the monitor screen as curves graphs simulating those made by a plotter on moving paper WinEEG software includes graphic tools allowing the display of paper speed mm sec and sensitivity mV cm with 1090 accuracy A user can initiate stop
212. ission number of trials when the patient should ignore the stimulus but pressed the button instead Artifacts number of artifact trials RTI mean reaction time for the Ist button 2 mean reaction time for the 2nd button 1 mean square variation of reaction time for the Ist button var RT2 mean square variation of reaction time for the 2nd button 230 79 List of channel pairs and parameters for EEG coherence and EEG cross correlations dialog List of channel pairs and parameters for EEG coherence and EEG crosscorrelations E X Channel pairs of file First list Second list Third list Fel Aww Fpl Aw Le Mat used Fpl Avw F Avw Mot used Fp 1 Aviv Foe viv L Hot used Fpl Avw PFA F7 AvMw F7 AvMw Toa F7 AvMW FEAA Fecha F3 AAW All pairs T24wwW C All pairs F3Avw Faaa f All pairs Fava Fast Pad Av Aviat TAa AW F4Avw selected pairs Fpl AvW Fav Selected pairs Selected pairs Fpl Avw PA Taha Coed F3 w Aw TES Aw TIA Coc Cov Poway Sha Pa Av hw Coty Cdl P3 Avw 01 Av AV 02A Fpl Avw CoA T a CoA hw Dd Paka Pz A MW TAA P3 Avw Fp2 Avw
213. iters are the most convenient and relatively cheap A CD or Writer costs 30 50 and a 700 Mb optical disk and 4 7 Gb DVD disk costs less than 1 So we recommend this device for EEG archiving Finally what to archive EEG files of course are most valuable and in a number of cases unrecoverable After system setup these files will be stored in the DATA folder and named as D0000001 EEG D0000002 EEG D0000003 EEG etc These names are assigned automatically by the built in database Final report texts are also stored as DO0000001 RTF D0000002 RTF D0000003 RTF or D0000001 DOC 32 D0000002 DOC D0000003 DOC etc Processing results such as power spectra or EEG indices and IDX files respectively can also be of a certain value In addition there are database files eegbase dbf spcbase dbf idxbase dbf erpbase dbf bfbbase dbf etc in the WinEEG working directory These contain information necessary for automatic data searching and also links to data files If you have EEG files or processing results stored it 15 always possible to restore database files but it can take plenty of effort So we recommend archiving database files regularly Note that the placement of database and EEG files is not fixed and can be modified by user So additional attention may be needed to archive and duplicate data properly Digital EEG Filtering WinEEG software offers at least two methods of digital EEG filtering The first metho
214. k Bar command Run this command to show or to hide Biofeedback bar containing controls for a number of additional parameters affecting EEG acquisition and processing during biofeedback sessions To learn more see Biofeedback Bar 55 View Toolbar gt Calculator Bar command Run this command to show or to hide Calculator bar in a spectra window or an indices window used to define processing for the Formula mode To learn more see Calculator Bar 56 View Toolbar gt Averaging Groups Bar command Run this command to show or to hide Averaging Groups bar in an ERP window offering a choice of four trial groups to be depicted on ERP graphs To learn more see Averaging Groups Bar 57 View Toolbar gt Customize Main Toolbar command Run this command to customize main toolbar by adding deleting or moving buttons Customize Toolbar dialog appears on calling this command 58 View Toolbar gt Customize Input Control Toolbar command Run this command to customize Input Control toolbar by adding deleting or moving buttons Customize Toolbar dialog appears on calling this command 59 View Toolbar gt Customize Analysis Toolbar command 117 Run this command to customize Analysis toolbar by adding deleting or moving buttons Customize Toolbar dialog appears on calling this command 60 View Status Bar command Show or hide status bar that displays hints for menu items or bar buttons along with indicators for Caps
215. k artifact parameters fields define a usage and limitation for corresponding parameters values using during searching and elimination of eye blink artifacts The set of eye blink artifact parameters are the following l 2 Remove eye blinks define usage of eye blink artifact detection procedure Dipole location Y coordinates and Dipole location Y coordinates fields define an appropriate values of Y and Z coordinates of dipole source of eye blink artifact wave Dipole eccentricity ECC field defines an appropriate value of eccentricity of dipole source of eye blink artifact wave Polarity field defines a polarity of eye blink artifact wave Waveform duration ms field defines minimal duration of eye blink artifact wave 204 Attention Both monopolar and bipolar montages could used for EEG to which automated spike detection 15 applied But dipole source parameters will be not estimated for EEG at bipolar montage 59 Averaged spikes calculation dialog Averaged spikes calculation X Time interval Selection Fragment 103750 OOo Ful EEG file Duration of base line time interval m Duration of paststimulus interval m 350 Calculate statistical significance 0 1005 _ ______ Cancel Time Interval Define EEG interval to be processed Selection Process interval between two vertical markers Fragment Process fragment selected from the
216. l dashed lines showing zero level for each channel in EEG window Channel Baselines Calibration In Channel Names User Labels Numbers showing gains uV cm to the right of the channel names in the Channel names bar Graphic object marking EEG interval of specific interest to user 254 97 Preferences Scale dialog Monitor Size Choose the display size corresponding to your monitor Then using the two sliders adjust the square size so that its width and height are exactly 30 mm This will provide proper horizontal and vertical screen scaling Use sliders to fine tune EEG scaling on the screen Preferences EEG input EEG window Scale Printing Monitor size x mm Help 233 98 Preferences Signal polarity dialog x EEG input EEG window Scale Signals polarity Printing Signal polarity Far EEG window C Minus Up Signal polarity for ERP f Plus Up Minus Up Signal polarity for EEG window Select appropriate signal polarity for EEG window Signal polarity for ERP Select appropriate signal polarity for ERP window 256 99 Preferences Printing dialog Paper orientation for EEG window Choose paper orientation for printing EEG Paper orientation for EEG mapping window Choose paper orientation for printing EEG maps Paper orientation for spectra window Choose paper orientat
217. l groups quickly use Select and Deselect buttons 168 Data Choose what data to export Waveforms themselves or Performance Data table Time Interval Set the time interval you wish to export data for The following interval parameters need to be set From sets the starting point You can start at the very beginning of the trial or at the moment when one of the stimuli is presented From ms sets the beginning of the interval to export in relation to the starting point To ms sets the end of the interval to export in relation to the starting point Step sets sampling interval for the exported data If the Step value exceeds sampling interval for source data adjacent readouts are averaged Baseline correction Specify parameters for baseline correction To left from Define stimulus before time interval will be chosen for estimation of baseline average potential Length Define length if time interval used for estimation of baseline average potential Format Choose format for ERP export If you choose the Channels In Line option ERP data will be written as follows Ch1 Ch2 Ch 1 2 Ch Ch1 Ch Gr1 Gr1 M Gr2 Gr2 M Gr M Gr 1 Gr 2 K Gr K TRI TR2 D D D BEES EMEN NE ZEE ee TRN D D D D D D D D If you choose Time Samples In Line option ERP data will be written as follows
218. l spherical volume conductor model of head used by dipole source localization method 1s presented by C J Stol J W H Meijs M J Peter Inverse solution based on MEG and EEG applied to volume conductor analysis Phys Med Biol 1987 V 32 No 1 P 99 104 Least square solution if inverse problem is performed by Nelder Meade simplex method W H Press S A Teukolsky W T Vetterling B P Flannery Numerical Recipes in C The Art of Scientific Computing Second Edition Cambrige University Press 1992 994 p Used in WinEEG program optimization of forward model parameters computation was presented by Sun M An efficient algorithm for computing multishell spherical volume conductor models in EEG dipole source localization IEEE Trans Biomed Eng 1997 V 44 P 1243 1252 Attention Many authors prefer to use average referent montage for dipole source A localization to eliminate influence of reference electrode signal Attention Please do not forget that an accuracy of dipole source localization method can be bad due to a number of different factors incorrect head model large errors in electrode coordinates existing more than one brain electromagnetic source and etc WinEEG and LORETA WinEEG have simple user interface that helps to transfer data from WinEEG to LORETA program LORETA program 15 rather popular software for 3D mapping of EEG or ERP voltage distribution or EEG frequency band power into 3D Talairach atlas For more information se
219. lash pairs 105 EEG Bandranges dialog Select a list of frequency bands which parameters you would like to modify EEG Bandranges x List name Default From Hz hs DE Es TN po Bo p p p p p Bandrange 1 Hame Deta Tea Ma 2 E Change Change Change Change Change Change Change Change Change Change Change Change Change Change Change CU feta Change Cancel Defines names limits and graph colors standard EEG frequency bands You can define up to sixteen frequency bands A desired frequency band will be used in processing only if the checkbox to the left of the frequency band name 15 checked Use List name list to select list of frequency bands Press a Color button to display Colors dialog 262 Press a Change button to display Parameters Of Bandpass Filter dialog changing frequency band limits and filter parameters 106 Parameters Of Bandpass Filter dialog Parameters of bandpass filter Filter Response Function Impulse response 10 20 30 40 50 60 70 80 30 100 110 120 Filter Response Function dE Filter response 20 30 40 50 60 70 80 30 100 110 120 Low cut Fass 14 0 Hz Stop 120 Hz High cut Pass 20 0 Hz Type Kaiser
220. lated EEG coherence And other types of file Save In Choose a folder on a drive or a network to place the new file in 165 19 Import of EDF data dialog The EDF data export procedure is used to convert EDF data to EEG format Import of EDF data Waveforms IS 512 FF EEG Theta 2 Phiz103 2 FP24 amp 172 912 uv PEPE x FP2 EEG Theta Phi 1 3 FRAT AZ 512 ou PEPE A F7 EEG Theta Phiz145 4 F34A amp 17 Z 512 ww PEPE e F3 EEG Theta 48 Phi 12 9 F2 41 AZ 512 PEPE EEG Theta 36 Phi 4441742 512 uv PEPE A F4 EEG Theta 48 Phi 53 7 FE4AT7A2 512 ww PEPE e F8 EEG Theta Phi 35 T34A1 7 2 512 PEPE T3 EEG Theta Phi 180 3 C3HA17 2 512 ul PEPE A C3 EEG Theta 36 Phiz180 10 C2 41 42 512 ww PEP A EEG Theta 0 0 11 C44517 82 512 ww PEPE 4 EEG Theta 36 Phi 0 12 1444142 912 uw PEPE T4 EEG Theta Phi 0 13 1544142 512 PEPE A T5 EEG Theta Phiz215 14 512 PEPE EEG Theta 48 Phi 233 15 P2 A1 512 PEPE EEG Theta 36 Phi 270 16 P44 amp 17 amp 2 512 PEPE A P4 EEG Theta 48 Phi 307 17 TE4 amp 17 amp 2 512 ww PEPE e EEG Theta Phi 325 19 512 PEPE 01 EEG Theta Fhi 251 1 19 0241742 512 uv PkFPk A 02 EEG Thetaz 72 i Uim k Change attributes of signals Time events Ty
221. ld value 15 set low amplitude oscillations beta rhythm most likely will be lost In addition these algorithms are unstable in the presence of circuit noise if its level is significant So it is impossible to offer unified recommendations for choosing the optimal amplitude threshold setup especially in view of the dependence of noise level on montage parameters and the notch filter use Here we list a set of parameters that 15 optimal from our point of view low frequency filter 30 Hz notch filter 37 50 Hz 1s on absolute peak to peak threshold 3 uV The peak to peak threshold should be chosen to exceed the amplifier noise level for the chosen bandwidth Selection of half wave detection algorithm 1s also not trivial If you use the algorithm based on zero crossing detection processing will detect low frequency high amplitude oscillations caused by signal baseline fluctuations generated by motor or vascular artifacts The influence of artifacts can be reduced by choosing a lower frequency limit We recommend the value of 0 1 sec or 1 5 Hz Unfortunately even in this case estimated EEG indices would be offset towards the low frequency range For example high frequency low amplitude signal oscillations 1n the beta range are often observed against high amplitude low frequency potential fluctuations In this case the zero cross half wave detection algorithm will not detect the high frequency signal components However at the same time the resu
222. lding the right mouse button pressed 141 Analysis Channels Groups command Display ERP graphs in an ERP window arranging them in columns by channels and in rows by trial groups Shortcut Analysis toolbar 142 Analysis Groups Channels command Display ERP graphs in an ERP window arranging them in columns by trial groups and in rows by channels Shortcut Analysis toolbar 143 Analysis Time Groups Mapping command Display ERP maps in an ERP window arranging them in columns by time readouts and in rows by trial groups Attention Maps cannot be viewed if source EEG was reformatted to a bipolar montage before processing Shortcut Analysis toolbar 144 Analysis Groups Time Mapping command Display ERP maps in an ERP window arranging them in columns by trial groups and in rows by time readouts Attention Maps cannot be viewed if source EEG was reformatted to a bipolar montage before processing Shortcut Analysis toolbar 8 145 Analysis Formatted Page command Display ERP graphs and maps in an ERP window Graphs are placed in the window according to defined ERP display format see Setup Graph Formats command 133 Attention Maps cannot viewed if source EEG was reformatted to a bipolar montage before processing Shortcut Analysis toolbar 146 Analysis Average Bandpower command Display average EEG band power graphs for wavelet ERP analysis in an ERP window
223. lect all trials 1n file Press Set button to set a new label value for the trials selected The new label value must be set beforehand in the Value field of the Set group Press Replace button to replace all trial labels matching the value in the Old Value field with a new value defined in the New Value field Press Load button to load trial labels from selected ASCII file Press Save button to save trial labels to selected ASCII file The last options allow also modify manually a structure of trial a number of presented stimuli and intra stimuli intervals 190 47 Adjust trial synchronization using synchro impulse dialog Adjust trial ynchromization using synchro impulse 1 X Synchro impulse channel Impulse polarity Positive C Negative Threshold uM 20 100 cancel Use Synchro impulse channel list to select channel to which synchronization signal is recorded using special detector for example photodiode Use Impulse polarity group of fields to define the appropriate polarity of the synchronization signal Threshold Enter appropriate voltage threshold to detect the beginning of synchronization impulses The threshold should be defined as low as in 1s possible but higher the amplifier or detector noise Attention The synchronization signal should be recorded from first stimulus in the trail There is way to adjust the beginnings of all stimuli in the trial except one
224. les compression 10 x Video Compressor Microsoft MPEG 4 Video Codec v1 ammressar properties Audio Compressor MPEG Layer 3 Save audio track File aoo ILLMLLIVTLNXAALLLLL L LLLL Total files Play source Compression Play destination Cancel Stop The following options allow you to specify how the video files should be compressed Video Compressor Select appropriate video compressor from a list The best choice in mane cases is Microsoft MPEG 4 Video Codec V1 or Microsoft MPEG 4 Video Codec Audio Compressor Select appropriate video compressor from a list The best choice in mane cases is MPEG 3 Save audio output stream Check this button if you would like to keep audio signal in resulting video file Compressor properties Select and modify compressor properties Play source Play back source video file 179 Play destination Playback compressed or re compressed video file The raw video file will be compressed before playing back function will be started This option helps to choose the best compressor before beginning the video compression procedure Stop Stop playing back function OK Start video compression procedure Attention Not all existing compressor from a list can be compatible with source video files Attention A number of compressors can unrecoverable decrease a quality of video signal Attention A number of
225. lifier Mitear FFG 202 model 401 or 404 Photastimulator jj Mifsar MITSAR EEG 202 keyboard pom p Hz CN O WinEEG f Fp2 o F4 o Ti ca cz c4 T4 Pa T o o e o b N s 4 1 Oz lt On oO o HO LJ 0 1 2 3 4 POLY i o u00 o oO L cable amp i Power sockets Power cable cable Patent Power adapter Warning for medical devices Power calle n gt Power adapter for medical devices Power cable 3 4 The EEG recording system based on Mitsar EEG 202 amplifiers model 401 and 403 Computer Amplifier Matssu EEG 202 model 404 406 Photostmmnulato LA Mitsar MITSAR EEG 207 Keyboard E n POWER Fete eere Fpz Fp2 Y WinEEG Um HM i SE FC T3 Cz C4 T4 cpa TPS Q z T5 P3 Pz PA T6 1 oO O Of N oa Oz 02 Printer N N Photostunnl ator cable Power T sockets Power cable f USR cable Panent Power adapter waning for medical devices button 4 Power cable C 3i Power adapter for medical devices Power c
226. list Full EEG file Process the whole file Duration Of Base Line Time Interval ms set the duration of interval used for base line estimation before spike pick Duration of poststimulus interval ms set the duration of the interval after spike pick Calculate Statistical Significance check this option to calculate statistical significance of difference of spike wave from baseline The Student criterion 1s used to estimate statistical significance 205 60 EOG Rejection dialog rejection EOG Channel Choose appropriate EOG channel from list Polarity Choose Positive or Negative polarity for first EOG extreme caused by blinking Threshold uV Set threshold value for detecting EOG signal caused by blinking Duration ms Set average duration for EOG signal caused by blinking Press Reset button to undo previous EOG rejection 206 61 Search and rejection artifacts dialog This dialog allows specify parameters of automatically detection of parts of EEG record including artifacts signals and mark corresponding time intervals The detection bases on threshold comparison of absolute voltage of EEG signal and amplitude of show and fast waves with defined thresholds Search and rejection artifacts i X v Voltage Threshold Condition Level uv 100 Slow Waves Amplitude 50 Frequency from 0 to 1 vw Fast Waves Amplitude peo Frequency from 20 to 35 Include interval betore ms
227. lization From 0 00 D b4 0 Hz w Statichics Mone E Channel Fpl vw ZEE NI PE 11 Calculator Bar 97 This bar 15 located at the right side of EEG mapping spectra or indices windows ts controls depend on window type At the top of this bar 15 a color scale Numbers above and below the scale indicate parameter values corresponding to highest and lowest color degree Below the color scale are controls for setting color scale sensitivity size of maps or graphs etc To learn for additional details about these controls see the sections describing particular windows Delta Theta Alfa Beta Beta2 Gamme Delta Theta Alfa Betal Beta2 Gamm This bar is located at bottom edge of the EEG Spectra window or EEG Indices window and is used to define a formula for calculating a value to be mapped in the Formula mode The bar has two rows of buttons corresponding to standard EEG frequency bands The top row defines the sum for ratio numerator and the bottom one for ratio denominator The standard EEG frequency band parameters signal powers or EEG indices marked by checked buttons will be summed when calculating the ratio of numerator and denominator For example if Alpha and Beta buttons are checked in the top row and Delta and Theta in the bottom row then the following power ratio would be
228. lt 0 000 1 02 lt 0 000 113 59 241 FS AvW 9 08 p 0 002 4 48 p lt 0 986 5 50 p 0 014 0 41 p lt 0 708 5 60 p lt 0 089 2 04 p lt 0 081 Se 3 AVW 4 15 p 0 249 7 59 lt 0 082 5 14 p lt 0 015 3 35 p lt 0 002 1 55 4 33 lt 0 008 27 38 8 Teta 000 0 00 Betal d 2 uy 2 uy 30 00 Delta 20 00 5 000 Betaz Gamma F 000 uv uy 242 3 000 3 000 3 000 3 000 3 000 Teta 3 000 Alfa 3 000 Beta 3 000 Sp SD Sp SD 3 000 3 000 Betas 3 000 Gamma 3 000 Sp SD Comparison of normalized power spectra 90 Normalization frequency band 0 0 64 0 Hz Pda mea Am Beo Gamma C3 AvW 13 30 lt 0 002 15 50 lt 0 362 23 06 p 0 011 9 62 lt 0 000 0 29 p 0 309 0 20 lt 0 500 243 20 00 30 00 40 00 20 00 Delta 20 00 Teta 30 00 Alfa 40 00 Betal 20 00 20 00 20 00 Betaz 20 00 Gamma 20 00 pa pa 3 000 3 000 3 000 3 000 Delta 3 000 Teta Sp Alta 3 000 Betal 3 000 SD SD 3 000 Betas 3 000 Gamma 3 000 Sp SD Comparison of average frequency Hz 0 16 p 0 000 0 17 p 0 767 0 Total Fpl AvW Fp2 AvW 7 F3 AvW Fz AVvW F4 AvW F8 AvW 3 AVW C3 AvW Cz AvW C4 AvW 4 AvW 5 AvW QN gP me Uv m O gP P 5 C P OO o
229. ltiple subject responses during specified processing time interval Consider multiple response as group of fields One of the following options can be chosen Commission error all subject responses during specified processing time interval will be considered as commission errors Correct response all subject responses during specified processing time interval will be considered as correct subject response Press Reset to reset default parameters Press Cancel to cancel response processing Note Response processing results can be viewed in Results Of Averaging And Subject Response Processing dialog called by Analysis Group Info command in an ERP window 221 73 Parameters of ICA spectra calculation dialog Parameters of ICA 5pectra calculation X Time interval Selection C Fragment 08 31 07 Ful EEG file Epoch lentah Time window C 1 second C 16 seconds C 2 seconds C 3 seconds 4 seconds C 64 seconds B8 seconds Upper spectra frequency Hz Artefacts elimination Polinornial trend Slow waves Power of signal 200 C Square Bartlett f Hanning C Welch Bandrange 0 5 s 1 25 Add all Delete all Load Save Add Delete Current iteration Cancel Channels Select the channels which signals you wish to process Use Add Delete Select All and Deselect buttons Time Interval Define EEG interval to be processed S
230. lts obtained by means of this algorithm will correspond better to those of spectral analysis although not precisely On the other hand the algorithm of half wave detection from local extremes is less sensitive to motor and vascular artifacts and 1s also more sensitive when detecting high frequency low amplitude signal oscillations The results of EEG indices analysis by means of these methods are the closest to visual EEG estimations Though this method leads to some offset of the indices toward the high frequency range we consider it to be the most stable But unfortunately this approach 15 used practically nowhere and seems to be original That certainly is a significant disadvantage for its implementation in routine encephalographic investigations So if you still have not given up EEG indices analysis here are some recommendations that of course must not be considered as dogma 1 Choose the bandwidth we recommend 0 1 sec for low cut and 30 Hz for high cut 2 Turn on the notch filter 3 Set the absolute threshold near 3 uV 4 Choose an appropriate algorithm of half wave detection the local extreme based algorithm has a number of advantages but 1f you use it further comparison of results with the limited existing data will be complicated The algorithm choice therefore 1s defined by your goal 5 Either fix the chosen parameters once and for all or systematically investigate the dependence of results on control parameters D
231. mat for successful database search by time Investigation Select investigation type from list 1 EEG observation Patient Enter patient s name Patient ID Enter patient s card number Diagnosis Enter a brief disease diagnosis The final report may contain more detailed description Date of birth Enter the date of patient s birth Use DD MM YYYY date format for successful database search Sex Enter patient s sex M F Address Enter patient s address Note Enter other useful info patient s insurance policy number for example the fields of patient card are not mandatory but can be useful when searching database Remember that all patient info would be automatically added to the final report The fields are placed below used for EEG monitor control The fields with information about available disk free space place near patient card 2 Montage Parameters Channels dialog Use the Channels tab of the Montage Parameters dialog to define the list of channels included in the montage and for setting their parameters You can also choose a montage from the montage list see Setup Montage List command 144 Montage parameters B Patient Card Channels Electrodes 1 0 5 0 53 Hz AFF 0 00 Montage name Monapolar 32 chan amp 1 amp 2 2 Fp2Ref Duc 0 3 0 53 Hz 45 55 Hz Electrode Referent 3 F
232. montage cannot be mapped Choose a Shortcut Main toolbar 92 Analysis EEG Indices command Calculate EEG indices for a selected EEG interval and opens an EEG Indices window for the active EEG file You can open several indices windows for one active EEG file but there can be only one window for any specific record interval Use vertical markers in the EEG window to mark an interval of interest An interval for processing must not be shorter than 1 sec After calling this command the Parameters of EEG Indices Computation dialog is opened to set additional processing parameters Raw data is processed according to montage parameters maps of indices choose a monopolar montage for the active EEG window before calling this Attention EEG reformatted to a bipolar montage cannot be mapped If you wish to view command Electrode coordinates are additional parameters for maps see Montage parameters Electrodes dialog Incorrect coordinate settings can disable mapping Shortcut Main Toolbar 93 Analysis EEG Spectra command Calculate EEG power spectra for a selected EEG interval and opens an EEG Spectra window for the active EEG file You can open several spectra windows for one active EEG file but for different intervals Use vertical markers in the EEG window to mark an interval of interest An interval for processing must not be shorter than 1 sec After calling this command the Parameters of EEG Spectra Co
233. mponent2 Variancez13 747 ICA window for independent component spectra The topographies of components are placed on the left side of ICA window The power variance of components is placed below topographies The bitmaps displaying individual not averaged components spectra are place on the right from topographies The average components spectra are displayed by curves places below bitmaps Each row of bitmap corresponds to single epoch spectra or individual spectra The first spectrum 1s displayed on the bottom of bitmap The x axis corresponds to the frequency The power of spectrum 15 coded by color The curve displays average power spectra of EEG component The parameters of equivalent dipole source for component topographies are displayed on right side of window Here RRE is Residual Relative Energy allowing estimate the accuracy of fitting of real data by dipole model and ECC 15 eccentricity of dipole The frequency of selected by mouse spectrum harmonic 15 displayed on status bar The design of ICA window for independent components of ERPs is presented on following figure 67 251 PP PH ica 2 1000 Dag 9 RRE 0 002 ECC 0 12100 Component Variance 4 664 EP ph OOGA RRE 0 032 ECC 0 23482 Lomponent2 Variance 1
234. mputation dialog is opened to set additional processing parameters Raw data is processed according to montage parameter spectral maps choose a monopolar montage for the active EEG window before calling this Attention EEG reformatted to a bipolar montage cannot be mapped If you wish to view command 124 Electrode coordinates are additional parameters for maps see Montage parameters Electrodes dialog Incorrect coordinate settings can disable mapping Shortcut Main Toolbar 94 Analysis EEG Cross correlation command Calculate EEG auto and cross correlation for a selected EEG interval and opens an EEG Spectra window Auto and Cross correlation for the active EEG file You can open several spectra windows for one active EEG file but for different intervals Use vertical markers 1n the EEG window to mark an interval of interest An interval for processing must not be shorter than 1 sec After calling this command the Parameters of EEG Auto and Cross correlation Computation dialog is opened to set additional processing parameters Raw data is processed according to montage parameters 95 Analysis Spectra Density Array command Calculate and display hide spectra density arrays in EEG window for the whole EEG file 96 Analysis Source distribution LORETA command Run this command to call LORETA application and store to it the voltage data corresponding to position of vertical markers Before the first call of
235. ms are displayed on Raw EEG plot The Corrected filtered EEG waveforms are displayed on Corrected EEG plot The pure artifacts filtered artifacts waveforms are displayed on Excluded Artifacts plot The waveforms of EEG signal components are displayed on EEG components plot The amplitudes of these components are printed right to the waveforms The topographies of EEG signal components are displayed by Topographies maps The Scroll bar is used to change the beginning time point for all mentioned above waveforms The buttons Gain and are used to change vertical scale sensitivity for all waveforms 208 The buttons Speed and are used to change horizontal scale speed for all waveforms The group of buttons Method is used for selection of EEG signal decomposition 1 method using singular value decomposition SVD and 2 ICA independent component analysis method can be used for this goal The button Invert filter allows estimate spatial filter so that Corrected EEG and Excluded Artifacts will be flipped This possibility allows separate clean EEG component waveforms from mix of components in raw EEG for the future processing Click on Map of topographies to include exclude it to from the data set used for spatial filter estimation Click Save topographies button to store the selected topographies to ASCII test file Attention The algorithm of artifacts correction 15 not ideal That is why the vis
236. n EEG spectra window Shortcut Analysis toolbar 135 Analysis Bicoherence command Display bicoherence frequency frequency plot in an EEG spectra window Shortcut Analysis toolbar 136 Analysis Average Spectra command Display average spectra in an EEG spectra window Shortcut Analysis toolbar x 137 Analysis Spectra Dynamics command Display spectra dynamics in an EEG spectra window Shortcut Analysis toolbar 138 Analysis Parameters of interaction diagrams Run this command to modify parameters of interaction diagrams used channel pairs and thresholds After calling this command a List of channel pairs and parameters for EEG coherence and EEG cross correlations dialog is displayed to modify these parameters 139 Analysis Insert tables into report Run this command to insert detailed report into the text of MS Word window This option 15 available only if raw spectra are kept during computation of power spectra see Parameters of EEG spectra 132 computation dialog After calling this command an Insert table of spectra parameters dialog is displayed to define a set of inserted tables and maps 140 Pop up Menu of Spectra Window Add Map command Add a map in Spectra window The map is added for selected frequency component or frequency band in dependence on displaying mode of Spectra window A frequency component may be pointed to on a graph or selected in a histogram by cursor position when ho
237. n de Walle A New Method for Detection and Source Analysis of EEG Spikes 3 Bart Vanrumste Richard D Jones and Philip J Bones DETECTION OF FOCAL EPILEPTIFORM ACTIVITY IN THE EEG AN SVD AND DIPOLE MODEL APPROACH 58 Proceedings of Second Joint EMBS BMES Conference Houston TX USA October 23 26 2002 4 A Ossadtchi S Baillet Mosher D Thyerlei W Sutherling R M Leahy Automated Interictal Spike Detection and Source Localization in MEG using ICA and Spatio Temporal Clustering Clinical Neurophysiology 2003 submitted 5 S Faul L Marnane G Lightbody G Boylan S Connolly A METHOD FOR THE BLIND SEPARATION OF SOURCES FOR USE AS THE FIRST STAGE OF A NEONATAL SEIZURE DETECTION SYSTEM The parameters of dipole source are used both for more exact spike detection and for eye blink artifact rejection For more information see description of command Analysis Spike Detection Analysis Spike Averaging Analysis Add Spike Analysis Delete Spike Analysis Change Channel Analysis Copy EEG Analysis Copy Spike Analysis Copy EEG to report Analysis Copy Spike to report and dialogue windows Spike detection and Average spike calculation Both monopolar and bipolar montages could be used for EEG to which automated spike detection 1s applied But dipole source parameters will be not estimated for EEG at bipolar montage Following diagram illustrates consequence of processing and analysis steps Automated spike detect
238. n spectra window Display spectra dynamics in spectra window Switch ERP window to Channels Groups mode Switch ERP window to Groups Channels mode Switch ERP window to Time Groups Mapping mode Switch ERP window to Groups Time Mapping mode Switch ERP window to Formatted Page mode Display average band power for wavelet ERP analysis 93 Display time frequency plots for wavelet ERP analysis Copy window contents and paste it into MS Word to current cursor position on instead selection Insert tables of EEG spectra parameters into MS Word 4 Status Bar The status bar is located at the bottom of the WinEEG window To show or to hide it run View Status Bar command The left part of the status bar displays a brief description of a menu command a toolbar button a Filters bar control an Input Control bar control or a Channel Names bar control pointed to by the mouse cursor used e g to preview a software action by hesitating with the mouse cursor on a command item to ensure the intended action will take place when the mouse button 15 clicked On the right side of the status bar there are fields displaying values for a selected EEG channel or spectrum or ERP parameters evaluated at the marker and indicating states of the locking keys Field Description For EEG window L Instantaneous EEG value at left marker Instantaneous EEG value at right marker T R L time interval between markers R L Differen
239. nce for the first trial group will be shown under the graph Graphs will not be displayed for channels or trial groups absent in the opened ERP file Check table rows for graphs to be depicted in the ERP window or highlight a row rows to modify parameters for Press Change button to set new parameters for displaying graphs checked in the table The Parameters Of Graphics dialog is displayed after calling this command Press Copy From button to copy parameters from another format selected from list The Page Size dialog is displayed after pressing this button 108 Page Size dialog Page size Width mm Height mmn 20 Enter page width and height 265 109 Line Style dialog Line style Press a button to select an appropriate line style 110 Graphics Page Format List dialog Choose a format from list Graphics page formats list 4 channel Standard Standard Standard Standard Standard Standard Standard Standard Standard Standard Standard Standard Standard Standard Cancel 111 Parameters Of Graphics dialog Rectangle Enter graph size and coordinates of its upper left corner relatively to the upper left corner of the page If the graph size exceeds page dimensions they page dimensions will be increased Channel Select a channel to be depicted Waveforms Choose a trial group to be depicted by each of curves on the graph up to four groups can be
240. nd to change color scale palette and map appearance Use Edit Copy command to copy graphs or maps visible in the window to the clipboard They can then be pasted into final report text or into any application window WinWord Paint and etc by means of Edit Paste command The table of spectral parameters can be also copied to clipboard as text Use the File Save command to save newly calculated EEG power spectra in the database Use the Analysis Insert tables into report command disabled for auto and cross correlation to insert detailed report into the text of MS Word window This option 1s available only if raw spectra are kept during computation of power spectra see Parameters of EEG spectra computation dialog Use the File Print command to printout of content of window Graphs and maps are rescaled to fit single page 79 The preliminary review of printing form can be done using command File Print Preview 80 5 EEG Indices Window This window is designed for EEG indices analysis Ooitney Dmitry 0 0 Scale AU x Fill b Bandranges Size 100 Delta Theta L Alfa C Betal Beta L Gamm L L Deta Theta L Alfa Betal C Beta2 L right side of window there 15 the Maps Spectra Indices bar and at window bottom there is a Calculator bar The results of EEG indices analysis can be prese
241. ng paper emulation C Don t show C Oscilloscope emulation Color boxes Color boxes with values Use large input buffer for displaing the data Use save mode for data input slower Do nct redraw EEG window afrer sensitivity changing faster Monitoring Style During EEG Recording Choose EEG monitoring style Moving paper Scrolling EEG window from right to left emulation Oscilloscope emulation Redrawing EEG window from left to right Can be used if the computer is not fast enough to enable smooth EEG window scrolling Show DC Value For Each Channel During Recording unknown item in Russian Choose DC component monitoring style 292 Don t Show Do not depict DC value Color Boxes Depict as small colored boxes IIDSIMOVTOJIBHHKH KOTODBIX Use large input buffer for displaying data Check this button if you would like to have a possibility to redraw whole EEG window during EEG recording when horizontal scale is changed Otherwise only newly recorded samples will be displayed using new horizontal scale The disadvantage of this method 15 that it takes a lot of time and can cause the acquisition errors on slow computers Use save mode for data input slower Check this button if you would like to use save mode for EEG recording The file header will be saved to
242. nnel 1 data point 1 for channel 2 data point 1 for channel J data point 1 for channel 1 data point 1 for channel 2 data point 1 for channel 1 The data is processed before exporting according to the montage parameters band pass filtering and artifacts correction procedures and is stored to the file in micro Volts 3 European Data Format EDF that supported by software developed by another companies The data 15 processed before exporting according to the montage parameters band pass filtering and artifacts correction procedures 4 Universal Data Format UDF an extension of EDF data format 5 LEXICOR data format The WinEEG program 15 able to export EEG spectra EEG coherence ERP and to ASCII data format for the further processing of these data by STATISTICA or similar programs for more advanced statistical analysis The WinEEG program supports the next data formats for import raw EEG data recorded by other equipment 54 1 ASCII data format The columns of resulting data file correspond to montage channels and rows to time samples 2 European Data Format EDF that supported by software developed by another companies 3 Universal Data Format UDF an extension of EDF data format 4 NeuroScan CNT data format 5 NeuroScan EEG data format Grand averaging and Batch data processin The WinEEG program can compute grand average EEG spectra grand average EEG coherence grand av
243. ns Channel channel names Amplitude amplitude from pick to pick for signal of each channel and for selected by vertical markers time interval Frequency an approximate frequency of signals Difference a difference of voltages for selected by vertical markers EEG samples Extrema the minimal and maximal values of amplitude are marked in this column Press Insert into report button into insert this table in text of report A usage of MS Word is recommended 196 54 Parameters Of EEG Indices Computation dialog The basic definitions and algorithms are described in EEG Indices section Here only processing parameters are listed Parameters of EEG indeces computation Time interval C Fragment 65 5 12 15 47 Ful EEG Method Use crosszern Use local extrema X of stantard deviation 0 Absolute n my c Interval Define the EEG interval to be processed Selection Interval between two vertical markers Fragment Fragment selected from the list Full EEG file The whole file Method Choose an algorithm for EEG indices calculation Use Zero Crossings Select half of waves by base line cross points Use Local Extrema Select half of waves between a local minimum and its adjacent maximum or a maximum and its adjacent minimum Detection threshold Define half of wave detection threshold to filter noise of Standard Deviati
244. nsitivity Ohm cm are maintained with 1090 accuracy Color printing maintains hues when printing spectra graphs and maps Monochrome printers replace hues with gray levels 29 6 Maintaining EEG Database and Processing Results WinEEG has a built in database for simplifying data save and search Using this database is not mandatory but it provides features that are often useful These include automatic conditional data search long file archiving and record restoration tools and dividing the whole set of EEG records into several independent databases which may be placed on different changeable magneto optical disks or CD of large capacity Recording Off line analysis EEG spectra ERD database database Raw EEG database file Off Ime processmtz EEG spectra ERD working folder working folder Raw EEG working folder EEG midices ERCoh database database EEG mdices ERCoh working folder working folder ERP Auto Cross database correlation Anto Cross correlation vorking folder ERP working folder WinEEG software database structure Whole database is divided on two parts EEG recording database and EEG processing results database EEG recording database includes raw EEG database file the list of EEG observations and raw EEG working folder that is the storage of EEG data files and corresponding video movies files and final report files Off line EEG processing results database includes six
245. nted in six window modes that are switched from one to another by corresponding commands found on the Analysis menu Graphs Indices are depicted as graphs for each separate channel X axis frequency 0 25 Hz increments Y axis percentage of time that signal of a given frequency was detected Histograms Indices are depicted as graphs for each separate channel X axis frequency 0 25 Hz increments Y axis percentage of time that signal of a given frequency lay within a certain standard EEG frequency band Table EEG indices are listed in a table Maps Percentage of time a signal existed within a certain standard EEG frequency band Asymmetry Map of Asymmetry of EEG indices Formula Ratio of percentages of signal existence time for two standard EEG frequency bands is mapped Ratio formula to be mapped is defined by means of Calculator bar Use the Scale list or and keys to change color scale sensitivity or Y axis scale for graphs Use the Fill By list to choose how to fill areas under a graph or a histogram None Blank white areas Bandranges Fills areas by colors defined in the standard frequency band 81 parameters see Setup EEG Bandranges command Color Scale Fills areas by color scale showing index level Choose graph or map size from the Size list For Graph and Histogram modes Value and Freq Fields of the status bar are used showing level and frequency for an index indicated by cursor on a
246. ntion If I O Port is chosen incorrectly EEG cannot be acquired and any attempt to start EEG input will cause error Attention This field can be disabled in a number of WinEEG versions Use button Find in this case to perform automatic search of connected to computer Mitsar amplifiers Synchronization Port To Which a Slave Computer Is Connected Choose a COM port to connect a slave computer presenting stimuli for ERP investigation to and specify its parameters Equipment configuration Amplifiers type Mot respond LO pork Sampling rate Hz Parameters of Synchronization Port Synchronization port to which a slave computer is connected 1 Baudrate 52600 Murmber of bita E Parity None Stop bits 1 Presentation device PSYTASK Parameters of port for external marks Serial port for extemal marks None Baudrate 1310 Humber of bits 4 Parity Even Stop bits 1 Graphics acceleration Method Turm alf w Iw Synchronization with Vertical Retrace Access codes Cancel 212 Parameters of port for external marks Choose a COM port to connect another computer sending external marks to and specify its parameters Presentation device Select presentation device The presentation device can be PSYTASK program or EXTERNAL Select EXTERNAL option if you would like to use Presentation program or E prime program Graphics acceleration Sele
247. o find the beginning of the selected EEG time interval Shortcut Main Toolbar 36 Edit Find Fragment command Find the beginning of an EEG fragment a trial Shortcut Main Toolbar 37 Edit Add Label command Add a user label run the command once more to turn Add Label mode off After calling this command choose label type from the popup menu The cursor will change its shape to Place cursor at desired position in the EEG window and click If you are adding a Channel or a Contour label also set its length by dragging to the desired length before releasing the left mouse button Shortcut Main Toolbar 114 38 Delete Label command Delete a user label run the command once more to turn Delete Label mode off The cursor will change its shape to Position it over label to be deleted and left click Shortcut Main Toolbar 39 Edit Patient Card command Edit patient card for the active file document The Patient Card dialog is displayed after calling this command Shortcut Main Toolbar E 40 Edit Trial Labels command Edit trial labels used for grouping trials in ERP calculations for the active EEG file The Modify Trial Labels dialog is displayed after calling this command 41 Edit Adjust trial synchronization command Adjust trial synchronization using synchronization signal recorded from special detector for example photodiode for the active EEG fil
248. ography button to export topographies table Check Equivalent dipole source button coordinates to export coordinates of dipole source equivalent to component topography Check LORETA maximum localization button to export coordinates of maximum of equivalent distribution of current density computed by LORETA method Check sLORETA maximum localization button to export coordinates of maximum of equivalent distribution of current density computed by sLORETA method If sLORETA maximum localization button is checked the sSLORETA transformation matrix location should be specified The Browse button to the right of name field 15 used to choose a drive and a folder 178 Check Power of component spectra for selected band range button to export table of spectra power for the list of frequency bands Check Percent of power of component spectra for selected band range button to export the table of percents of spectra power for the list of frequency bands Use List of frequency bands menu to define appropriate list see Setup EEG bandranges command The Volume areas for counting the number of components with corresponding dipole source coordinates table can be used for definition up to 16 cubic areas not implemented now The Output file name field is used to define full path for the file to export data to Use the Browse to the right of the name field to choose a drive and a folder 29 Video file compression dialog Video fi
249. olbar to learn how to use it 47 View Toolbar gt Maps Window command Run this command to show or to hide the side window that presents mapping potentials and other processing parameters depending on the positions of two vertical cursors 48 View Toolbar gt Dipole Window command Run this command to show or to hide the side window that presents dipole sources 49 View Toolbar gt Filters Bar command Run this command to show or to hide Filters bar which presents a number of processing options or window parameters for the active EEG window To learn more see Filters Bar 50 View Toolbar gt Maps Bar command Run this command to show or to hide Maps bar which presents data display options for the active EEG mapping window See Maps Spectra Indices Bar to learn how to use it 51 View Toolbar gt Spectra Bar command 116 Run this command to show to hide Spectra bar which presents data display options for active EEG spectra window See Maps Spectra Indices Bar to learn how to use it 52 View Toolbar Indices Bar command Run this command to show or to hide Indices bar which presents data display options for the active EEG indices window See Maps Spectra Indices Bar to learn how to use it 53 View Toolbar gt ERP Bar command Run this command to show or to hide ERP bar which presents data display options for the active ERP window To learn more see ERP Bar 54 View Toolbar gt Biofeedbac
250. ommand will be similar to 3 90 Je 3 90 9 RRE 0 036 0 32338 Component Varnance 1 737 3 400 2 0 171 Pop up menu of ICA window Component command Modify component name Component name dialog is displayed after calling this command 172 Pop up menu of ICA window LORETA for component command Runs LORETA application and store to 1 the topography of selected component 173 Analysis Export of component parameters command Save to the ASCII file the parameters of selected component for the future statistical analysis Export of parameters of independent component dialog is displayed after calling this command 174 Setup Database Pathnames command Create or opens EEG spectra and indices databases and customizes their parameters The Database Parameters dialog consisting of four tabs 15 displayed after calling this command Go from tab to tab to define parameters for Databases of Raw Data Databases of Processing Results and also Browser Settings and Base Record Search Parameters 175 Setup Preferences command Set graphic output parameters for EEG window Preferences dialog is displayed after calling this command 176 Setup Mapping Style command Modify map display style Mapping Style dialog is displayed after calling this command 137 177 Setup Montage List command Modify montages in the montage list A montage includes a number of options such as list of r
251. omponent The command Select groups from menu Analysis is used to select the list of conditions to which corresponding average curves will be displayed The command Select group pairs from menu Analysis is used to select the list of condition pairs to which corresponding difference waves will be displayed The command Change graph scale from menu Analysis is used to change vertical scale of the graph The command Correct baseline from menu Analysis is used to define the length of baseline time interval for baseline correction The command Save components filter from menu Analysis is used to save to ASCII file matrix A using as a spatial filter for transformation raw EEG ERP to components The command Save signals filter from menu Analysis is used to save to ASCII file matrix using as a spatial filter for reviling or suppression of signals from raw EEG ERP for selected list of components The command Export of component parameters from pop up menu of window is used to save to ASCII file the parameters of selected component for the future statistical analysis The Save command from submenu File is used to save newly calculated independent components ICA file The Save As command from submenu File is used to save independent components in ICA file with another name 89 WinEEG Bars 1 Main Toolbar The main toolbar 15
252. omposition dialog To perform wavelet decomposition additional information on stimuli presentation structure in each trial is used together with source data To group trials by stimuli types or by response task trial labels are used These parameters are defined beforehand when creating editing stimuli presentation protocols by means of PSYTASK program installed on the presenting computer Wavelet decomposition X Groups of trials Ma Mame Labels Correct Incorrect Artifact 1 1 0 0 0 2 2 T 0 T 3 E iC ae 4 c 3 1 2 0 0 0 5 E remp rm 7 0 s 0 0 0 0 0 Group differences E 4 3 5 5 Choose Artifact processing Synchronisation Subject response processing Level 100 p m eve T yp Stimulus Defined Channels EEG Stimulus 1 Threshold for channels Buttan channel Mot selected gt Time interval before ms Time interval after p Frequency from 40Hz gt Frequency to 40 0Hz gt Shep gt Wavelet width 5 cycles gt Substract ERP from raw EEG Smoothing 5 Hl v Use default 1002 Define Cancel Many fields of this dialog are similar to those of Parameters for Event Related Potential Computation dialog So only the additional fields are described below Frequency From Frequency To Choose two values defining frequency range for w
253. on Thresholds will be calculated for each separate channel from standard signal deviation Absolute uV One common threshold 15 set for all channels in uV 197 55 Parameters Of EEG Spectra Computation dialog The basic definitions and algorithms are described in EEG Spectra section Here only processing parameters are listed Parameters of EEG spectra computation Time interval s Fragment 14 00 15 t Ful EEG file Average defined epoch number only Epoch number 0 Channels EEG only Epoch lentgh verlapina Time window 1 second C 16 seconde mz f Square C 2 seconds t Bartlett t 32 seconds 4seconds None f Hanning t seconds B4 seconds t Welch Upper spectra frequency Hz B4 ES Artefacts elimination Palinamial trends 2 Slow waves Power of signal 1200 Bandrange 0 5 1 25 Bispectra Additional processing t t Spectra dynamics Averaging epoch t Calculate coherence Calculate coherence and phase spectra f Keep raw spectra Load Save Load from database 0 100 Cancel Time Interval Define EEG interval to be processed Selection Process interval between two vertical markers Fragment Process fragment selected from the list Full EEG file Process the whole file Check Average defined epoch number only button to compute the spectra and coherence with strong equal averaged epoch number This option 15 extremely useful
254. on describes the main features of the event related potential ERP acquisition tool We assume you are familiar with the ERP method WinEEG permits recording the simplest long latency visual evoked potentials evoked by a photo stimulator flash as well as event related potentials such as P300 wave mismatch negativity MMN conditionally negative variance CNV and many others In evoked response measurements an additional computer is used as a universal device for presenting visual and auditory stimuli It is connected to WinEEG computer by null modem link cable through the COMI or 2 serial port in order to synchronize stimulation and EEG recording The stimulus presenting computer should use PSYTASK 2 x software working in concert with WinEEG In addition a pushbutton connected to the ECG channel input or to digital input in dependence on amplifiers type can be used for monitoring user response Although EEG 15 being recorded non stop during the whole investigation non overlapping EEG intervals trials will be selected for ERP calculation for synchronizing signal and used for ERP summation If photo flash ERPs are recorded then trial length and pre stimulus interval duration are set as processing parameters In this case you may calculate ERPs for a selected EEG record interval for the whole record or for each fragment separately If an additional stimulus presenting computer 15 used trial length 15 defined b
255. on t try to manipulate parameters in order to reach a certain local goal for example to prepare a remarkable illustration for your EEG description 6 A final reminder there are no standards or norms for the methods of EEG indices analysis EEG Power Spectra This section describes the algorithm of power spectral computation We assume you are already acquainted with theoretical basis of spectral analysis If not you can find complete information in the book by J Bendat A Pirsol Random data Analysis and measurement procedure John Wiley and Sons NY 1986 540 pp As for the practical use of EEG spectral analysis in the diagnosis of diseases you can read specialized journals such as Electroencephalography and Clinical Neurophysiology Following diagram illustrates consequence of processing and analysis steps 36 Power spectra analvsis functional diagram Spatial High order Montage poud ag bandpass processing ers FIF filtering spectra calculation EEG datafile Calibration spectra window Database of observations spectra file Database of spectra EEG spectra analysis We will briefly describe the features of power spectral calculation algorithms implemented in WinEEG Suppose that we process a single interval of an EEG record 1 2 3 4 5 6 First of all the source record interval 15 reformatted and filtered according to th
256. onent topographies Compute spatial filter by clearing unchecked component topographies Pseudo inversion of component topographies Compute spatial filter by Moore Penrose pseudo inversion of rectangular not squared matrix of checked component topographies File Define output file name 85 Component name dialog Component name ES Cancel Enter new name for selected component 86 Export of parameters of independent component dialog Export of parameters of independent component Time interval From stimulus TRE From ms 0 ms 0 Baseline correction the left fram used Length ma S0 E a 13 He ay Add to existing file Cancel Specify parameters for export Time Interval Set the time interval you wish to export data for The following interval parameters need to be set From stimulus sets the starting point You can start at the very beginning of the trial or at the moment when one of the stimuli 15 presented From ms sets the beginning of the interval to export in relation to the starting point 235 Baseline correction Specify parameters for baseline correction To left from Define stimulus before time interval will be chosen for estimation of baseline average potential Length Define length if time interval used for estimation of baseline average potential File Define
257. ontage you must define a number of its parameters a Define a list of channels for EEG acquisition corresponding to electrodes really placed and connected see Montage parameters Electrodes dialog Define also coordinates of the electrodes b Define a list of channels in the montage and their parameters such as gain bandwidth and baseline see Montage parameters Channels dialog c Define colors for signal displaying see Montage parameters Colors dialog d Define referents to be calculated if there are any Av AvL and AvR see Montage parameters Referents dialog e Test whether channels are correctly defined or view another montage in the list see Montage parameters View dialog When the parameters are set press OK button to create a new EEG file A new blank EEG window appears on the screen Use Recording menu commands to start monitoring EEG and to manage photo stimulators Don t forget to save the new file in the database see File Save command when EEG monitoring is finished 107 Shortcuts Main Toolbar Keys CTRL N 2 File Open EEG Database command This command opens an EEG file from the database in a new window You can open several EEG files simultaneously Use the Window menu commands to switch between opened files See Window 1 2 command As you run this command a Record List dialog is displayed for searching EEG files in the database or in the archive Shortcuts Main Toolbar E K
258. opy Channel to Report command Copy channel s waveform map and dipole picture for active ERP group into text of final report The map and dipole picture will correspond to time sample selected by mouse pointer 156 Pop up menu of ERP window Source distribution LORETA command Run this command to call LORETA application and store to it the voltage data corresponding to selected time point of ERP data Time readout bit may be pointed to on an ERP graph by cursor position when holding the right mouse button pressed 157 Pop up menu of ERP window Dipole source BrainLock command Run this command to call BrainLock application and store to it the voltage data corresponding to selected time point of ERP data Time readout bit may be pointed to on an ERP graph by cursor position when holding the right mouse button pressed 158 Pop up menu of ERP window Delete All Labels command Run this command to clear all pick labels 159 Pop up menu of ERP window Delete Labels and Maps command Run this command to clear all pick labels and maps 160 Analysis Insert Patient Card command 135 Insert patient card into final report text Shortcut Main toolbar E 161 Analysis Generate Final Report command Activate final report generation procedure Only Russian version available 162 Analysis Insert Final Report Template command Insert a final report template into final report text Shortcut Main toolbar 1
259. or auto and cross correlation Formula A map depicting the ratio of signal powers for two given EEG frequency Mapping bands The ratio formula is defined by means of the Calculator bar For the Spectral Dynamics mode multiple maps are displayed Disabled for auto and cross correlation Formula Signal power ratio dynamics for two given EEG frequency bands Disabled Graphs for auto and cross correlation Interaction The EEG coherence and cross correlation can be presented by so called diagram interaction diagrams For EEG coherence electrodes will be connected by curves with different thickness and colors in dependence of value of average coherence For EEG cross correlation electrodes will be connected by curves with different thickness and colors in dependence of value first maximum extreme of cross correlation function 760 S5PC Grand Average File Fill b None L Size Betal Beta P x gt Normalization From LOC C 6 ES Stalictics Channel x En Deta lta Beta 0 Gamm O LT 0 Delta Tea lta 0 Betal L Beta Gamm L LT L L L L The window can display background EEG coherence and phase spectra as well as power spectra Bi spectra and bi coherence are displayed by frequency frequency color plots 1 Annalea Fui Rel F7 R
260. ort command Customize final report generator Final Report Generator Setup dialog is displayed after calling this command 186 Setup Final Report Templates command Define and modifies list of final report templates Final Report Template List dialog is displayed after calling this command 187 Setup Video recording command Select video capturing device Set and modifies parameters of capturing resolution frame rate signal format and on line compression Video recorder parameters dialog is displayed after calling this command 188 Setup Equipment Parameters command Set and modify hardware configuration Equipment Configuration dialog is displayed after calling this command 189 Window Cascade command 139 Cascades all open windows Shortcut Main toolbar 190 Window Tile Horizontally command Tiles all open windows horizontally Shortcut Main toolbar 191 Window Tile Vertically command Tiles all open windows vertically Shortcut Main toolbar 192 Window Arrange Icons command Arrange the icons for minimized windows at the bottom of the main window 193 Window Split command Split the active window into two panes 194 Window 1 2 command WinEEG displays a list of currently open document windows at the bottom of the Window menu Check a document from this list to make its window active 195 Help About WinEEG command Displays copyright and version number for
261. ow it controls allows to modify mapping parameters are placed Use the Scale list or and keys to change color scale sensitivity Use the Step list to change averaging epoch length Use the Size list to zoom maps Use the Setup Mapping Style command to change color scale palette and appearance of maps Use Edit Copy command to copy maps visible in the window to the clipboard They can then be pasted into final report text or into any application WinWord Paint etc window by means of Edit Paste command 74 4 EEG Power Spectra Auto and Cross correlations Window This window is designed for EEG power spectra and correlation analysis On the right side of the window there is Spectra bar and at the window bottom there is the Calculator bar Fil WinSpc1 Battaglia Gianna Bl Fpl Avw Fp2 Aviw 12 0 uv 2 0 0 uv 2 Faia F8 A yw Scale 124472 7 20 Value 4 80 P 2 40 Fill b None AW T4 Avw Size uv 2 100 7 20 i Normalization 4 80 From 2 40 0 00 Hz Me T5 MW Pz AvMW P4 Ayviw TE A 64 0 Hz 2 Statictics 7 20 am Channel 2 40 yl Aw 5 x a 10 20 lt e e a 4 4 M Deta Teta 0 Betal 0 Beta2 0 Gamm 7 O L1 O O O O O O L1 Delta Teta O Alfa 0 Beta2 0 Gamm L1 0 O O 0
262. p Til md EDF Annotations DOC 522 000 gt 5 4 000 gt 5 6 000 lt gt 5 9 000 gt 5 10 000 lt gt 5 12 000 lt gt 5 Fragment agg 2 EDF Annotations 5545 367 0 5 195 lt Artifact gt 5 55 064 1228 0 52 Baseline 5104 0 16 104 lt User mark 00 3 EDF Annotations Fragment ood 4 EDF Annotations 528 5Z3 5tart task gt 5 30 303 lt End Task gt 5 60 606 21 gt 5 67 38925 5 232 121 lt 2 Beginning of trial 200 100 700 gt Change attrubutes of time events Hypnagram file name Browse 0 100 Cancel Both Waveform table and Time events table helps to define list of signal channels and list of EDF annotations The Waveform table includes following columns No order number of channel Label name of channel written to EDF file Hz sampling rate of channel in source file Physical name of physical units for each channel Prefilter textual data described frequency bands Name name of channel for destination file Type type of data EEG Bio or Referent Coordinates spherical coordinates of sensors placed on the head for EEG channels only SUR EE CE Name Type and Coordinates channel attributes can be changed using Change attributes of signals button After pressing this button Channel attributes dialog will appear on the screen The Time events table includes following columns No order number of EDP annotation 2 Label fixed name EDF annotation
263. p up menu of EEG window Copy Spike to Report command Run this command to copy spike waveform into text of final report for selected spike 122 Analysis Graphs command Display processing results spectra or indices as graphs for each channel in an EEG indices window or in an EEG spectra window Shortcut Analysis toolbar 123 Analysis Histograms command Display histograms for standard EEG frequency bands for each channel in an EEG indices window or in an EEG spectra window Shortcut Analysis toolbar 124 Analysis Table command Display table of spectral parameters for standard EEG frequency bands for each channel in an EEG indices window or in an EEG spectra window Shortcut Analysis toolbar 125 Analysis Maps command Map spectral parameters distribution for standard EEG frequency bands for each channel in an EEG indices window or in an EEG spectra window Attention Maps cannot be viewed if the source EEG was reformatted to a bipolar montage before processing Shortcut Analysis toolbar 126 Analysis Asymmetry command 130 asymmetries in distribution of spectral parameters for standard EEG frequency bands for each channel in an EEG indices window or in an EEG spectra window Attention Maps cannot be viewed if the source EEG was reformatted to a bipolar montage before processing Shortcut Analysis toolbar 127 Analysis Formula Mapping command Map ratio of two
264. pboard or final report commands Copy Spike of Copy Spike to report of pop up menu could be used To do this artifact move mouse pointer to spike label press and release right mouse button and select appropriate command The next picture will be placed into clipboard or final report commands T4 v 300 0 9 300 0 8 0 035 0 9804 200 Attention The voltage map and dipole localization picture will be not added for bipolar montage To insert corresponding to spike waveforms of EEG into clipboard or final report commands Copy EEG of Copy EEG to report of pop up menu could be used The next picture will be placed into clipboard or final report commands 69 10 37 37 1 Fpl ay FF ae t Tm A LAC m aa i 01 A gt m Le us Ex A Attention Use MS Word only if you want to insert picture into final report 70 26 Display spectra density arrays To display Spectra density arrays use command Analysis Spectra Density Array The color bitmaps time frequency plots will be displayed at lower part of EEG window 19 WinEEG D0000059 EEG Decurtins Annalea visual CPT 10 48 50 Ioj x File Edit View Format Recording Analysis Setup Window Help x BEX f a we 4 hH lu 5 9
265. pecified criteria would be calculated and the others would be ignored Each edit box in the Statistical report dialog defines one search criterion A record satisfies search conditions if it contains all features that have been defined Blank fields are ignored during search Here 15 the list of search criteria that can be defined ID field contains a text string that must be present in the corresponding field of the database record If the text defined for search 1s shorter than 1n the database a substring 15 searched Symbol case 15 ignored blanks placing before and after the text are deleted If the ID field 1n the search condition contains ABC then records containing ABC abc AbCXXxxXX in their ID fields satisfy this condition Date From To fields define the interval of EEG acquisition dates current year for example To enable automatic search by date use DD MM Y Y Y Y date format Time From To fields define the interval of EEG acquisition times before noon for example To enable automatic search by time use HH MM SS time format Investigation field contains a text string that must be present in the corresponding field of the database record see also ID field Diagnosis field contains a text string that must be present in the corresponding field of the database record see also ID field Date of Birth From To fields define the range for dates of pa
266. pen several ERP files simultaneously Use the Window menu commands to switch between opened files See Window 1 2 command As you run this command a Record List dialog is displayed for searching ERP files in the database or in the archive 108 7 File Open Another Database gt ERD File command This command opens an event related EEG de synchronization ERD file from the database in a new window You can open several ERD files simultaneously Use the Window menu commands to switch between opened files See Window 1 2 command As you run this command a Record List Dialog is displayed for searching ERD files in the database or in the archive 8 File Open Another Database gt ERCoh File command This command opens event related EEG coherence ERCoh file from the database in a new window You can open several ERCoh files simultaneously Use the Window menu commands to switch between opened files See Window 1 2 command As you run this command a Record List Dialog is displayed for searching ERCoh files in the database or in the archive 9 File Open Another Database gt Biofeedback File command This command opens a biofeedback file from the database in a new window You can open several biofeedback files simultaneously Use the Window menu commands to switch between opened files See Window 1 2 command As you run this command a Record List dialog is displayed for searching biofeedback files in the
267. placed in top of the WinEEG window under menu bar It enables quick initiation of many WinEEG commands by simple mouse clicks To show or to hide the main toolbar use View Toolbar gt Main Toolbar command To change the arrangement of buttons in the main toolbar use View Toolbar Customize Main Toolbar command You can also move or delete buttons by dragging them while holding the Shift key down C lick To j M les 5 ij Create a new EEG file Open a data file EEG spectra file etc Click the arrow to open database list Save the active file to the database Close the active document Open the Export file format menu Print the active document Preview the active document before printing Exit WinEEG Undo last action when editing final report text Mark selected time interval of EEG record as artifact Cut selected block from final report text to clipboard Copy active window contents or selected block of text from final report to clipboard Paste the clipboard content to final report text Delete selected block from final report text or selected interval from data plot Find given text in the final report Find the beginning of selected plot interval Find the beginning of a plot fragment trial Add a user label or turn Add Label mode off Click the arrow to open label list Delete a user label or turn Delete Label mode off GN
268. plifiers dialog Attention Amplifiers are calibrated by manufacturer before metrological certification WinEEG user is only able to view calibration parameters not to change them The following fields allow viewing the table of correction parameters Parameters Choose what parameter set to view Parameters Table Table of gains and offsets 1s placed under Parameters list Calibration of Amplifiers Parameters Gan Aero Fpl 0 7407 1365 0 7299 12589 Fz 0 7352 1289 r5 1258 Fe 0 7462 i331 Pz 0 7407 1335 07407 1283 1348 01 cx 0 7462 1356 02 Cz 0 7407 1363 36 Find dialog Find Match whole word only Match case a ra 0 7407 0 7407 gc Iz c c ra c Z 1 L E 1 L b Do i 77 I na 184 Coefficients Far high sensitivity of amplifiers zen Biol po Bf arfi Bio fi fl Bo fl Eo Bg fi Cancel Find What Define the string to be searched for Match Whole Word Only Check to find only whole words matching the Find What string Match Case Extends search criteria to include uppercase and lowercase attributes while searching for the Find What string in the text Find Next Find next string match
269. port It 1s an arbitrary text 1n double quotation marks Special characters can also be used new line Vi line feed double quotation marks V apostrophe V backslash V goblock Block Identifier call of a block to be processed Transfer control transfer command There are four control transfer commands next goes to next menu default break finishes block processing quit stops the whole hierarchical menu processing system functioning go lt Menu Identifier gt starts processing the menu with the corresponding identifier There are several limitations for programming block calls and menu transfers Only a block can be called that is described in the text below the block currently processed A menu can call another menu only within a block and the menu to be called shall be described in the text below the menu calling it These limitations can complicate development of a user s own hierarchical menu system but they leave out the possibility of occurrence of closed loops and therefore simplify debug of the system Comments 276 Any text from a semicolon to end of line is treated as a comment and 15 not included in syntax analysis 4 Example of a Hierarchical Menu Program Here 15 a short example of a program showing all key words and features of the language You can analyze this text by yourself and having done it you surely will be able to create a hierarchical menu system as complica
270. quisition monitoring and recording The ensuing EEG fragment will be absent in the record The command is available only if a new EEG window is opened see File New command To resume EEG acquisition and monitoring or recording use the Recording EEG Monitoring command 120 Shortcut Input Control toolbar m 75 Recording Stop command Stops EEG acquisition monitoring and recording or EEG window scrolling and switches to EEG view mode see EEG Window The command is available only if a new EEG window is opened see File New command Before new file is saved in the database EEG monitoring and recording can be resumed by running Recording EEG Monitoring and Recording EEG Recording commands Shortcut Input Control toolbar 76 Recording Turn On Off Calibration command Use this command to start acquiring calibration signal 0 5 Hz 0 1 Ohm to the computer memory and monitoring it in the new EEG window without recording the signal to hard disk The command is available only if a new EEG window is opened see File New command To stop calibration signal acquisition and to start EEG monitoring run this command once more Shortcut Input Control toolbar 77 Video recording command Use this command to start recording the video data to hard disk The command 15 available only if a new EEG window is opened see File New command To stop recording the video data and to resume video monitoring mode r
271. r Ref 0 3 0 53 30 45 55Hz 0 00 EEG channels EEG channels 4 F3Ref iM a 03 0 53 30 4555H2 0 00 5 FeRef 03 D53Hz 30 4555Hz 000w 6 F4Ref 03 0 53 30 4555H2 0000 7 FoRef 03 D53Hz 30 4555H2 0 00 8 Pgi Ref 03 53Hz 30 45 55 0 00 3 Po2 Ref 03 053 30 45 55 0000 10 CbRe 0 3 D53Hz 30 4555Hz 0 000 11 T3Ref 03 D53Hz 30 4555Hz 0000 gar Eds 12 C3Ref 0 3 30 4555Hz 0 000 io channels 13 0 3 30 4555Hz 0 000 Eis Een Biss 14 C4 Ref 0 3 D53Hz 30 4555Hz 0 000 Bice Biod Bior Bice 15 T4 Ref 0 3 D53Hz 30 4555Hz 0 000 16 T5 Aef 0 3 30 4555Hz 0 000 17 P3Ref 30 4555Hz 0 000 18 PzRef 0 3 53H24 30 45 66 0 000 Gain 50 uv cm 19 P4 Ref 0 3 D53Hz 30 4555Hz 0 000 20 03 D53Hz 30 4555Hz 0000 Baseline 0 00 uv zi 21 01Ref 0 3 D53Hz 30 4555Hz 0000 0 53 Hz 22 D2Ref 0 3 D53Hz 30 45 55H2 0000 23 Biol 2 03 D53Hz 30 4555Hz 0000 High cut 30 2 Notch 50 Hz 45 55 Add Insert Delete Show all Hide all Montage Name This field initially contains name of default montage from montage list Use down arrow button to select a dif
272. rameters of EEG for given time interval 15 higher then threshold then this time interval 15 marked as artifact and eliminated from further processing Most power artifact detection and marking procedure is implemented in Analysis Mark Artifacts command This procedure makes three independent EEG signal parameters comparison with defined thresholds 1 The comparison of absolute voltage of signal with the threshold 2 The comparison of amplitude of slow wave in defined frequency band with the threshold 3 The comparison of amplitude of fast wave in defined frequency band with the threshold This procedure can be performed many times independently Command Artifacts from submenu Analysis runs this procedure Search and rejection artifacts dialog will appear on the screen and allows enter or change parameters of automatic artifact detection EEG Indices The section describes the algorithm for analyzing EEG indices and its features We should note that the method of EEG index analyses implemented in this software 1s more a research method than a standard routine That is why we recommend using this method only if you realize quite clearly what parameters and algorithms are used and what they mean We define an EEG index as the percentage of time that EEG potential fluctuations occurred within a given frequency range In other words if we have defined four standard EEG frequency bands alpha beta theta and delta then after
273. reated before starting EEG monitoring Before creating a new EEG file a number of EEG parameters should be defined in the Montage Parameters dialog box consisting of 7 tabs Switch from tab to tab to define parameters for a new EEG file 1 Fill in the patient card see Montage parameters Patient card dialog 2 Choose a montage from the existing list and or enter its parameters A montage includes a number of options such as list of monitored channels list of displayed channels and their parameters gains bandwidths baseline colors etc Don t forget that signals are acquired and recorded always monopolarly in relation to the electrodes connected with Al A2 inputs The bandwidth for acquisition and recording 15 maximally wide 0 15 70 Hz or 0 5 30 Hz Remember that 0 15 Hz frequency corresponds to 1 0 sec time constant and 0 5 Hz to 0 3 sec time constant This acquisition method allows convert raw data to any mono or bipolar montage with any bandwidth during subsequent viewing and processing created file and are not saved in the montage list If a parameter set is expected to be used many times it would be better to define it in the montage list see Setup Montage List command Next time you would simply select it from the list instead of repeatedly entering parameters which may take a considerable time Attention Montage parameters set by New command are active only for the currently When customizing a m
274. recorded EEG See EEG window 11 Open the Final Report window using the Analysis Final Report command 3l 12 Compose the final report and save it to the database using the File Save command 13 Print the final report and illustrative fragments of the EEG using the File Print command 14 Close the WinEEG window using the File Exit command Note The EEG recorded to the database 1s the raw one acquired using monopolar montage in relation to reference electrodes with the bandwidth 0 5 30 Hz for Mitsar EEG 2 or 0 15 70 Hz for Mitsar EEG 3 But the EEG displayed on the screen 15 reformatted and filtered according to the montage parameters that have been set see Setup Montage List command The raw EEG data may be reformatted into any montage without limitation Data Archiving Don t forget the main difference between paper and paperless technologies By recording an EEG on a paper sheet and putting it in a bookcase you can be absolutely sure it will be stored safely unless a catastrophe happens or an untidy colleague accidentally throws the EEG record in a dustbin We of course assume that you have effectively arranged your EEG records so you can find any particular one among all the others quickly and easily Paperless technologies help avoid storing kilometers and kilograms of paper on bookshelves and also simplify searching for necessary records But it 1s too soon for you to relax Unfortunately practically no opera
275. recording The EOG and EEG signals should be recorded using the same frequency bands Because additional artifacts can influence on quality of correction of eye blink artifacts the visual inspection of its result should be done 34 Correction of EEG artifacts Eye blink artifacts and some other artifacts can be corrected using this procedure even if the EOG signal was not recorded This method based on blind source separation procedure from multi channel EEG data and spatial filtering of some components of EEG signal The input data 15 manually selected time interval including artifacts Blind source separation can be performed using both principal component analysis PCA and independent component analysis ICA methods After the decomposition of milti channel signal the components of signal related to artifacts are selected manually based during the analysis of their topographies and waveforms of components The components corresponding to artifacts are cleared set to zero and corrected EEG waveforms are computed by multiplying artifacts topographies matrix and new components set In fact a spatial filter performing equivalent transformation 15 calculated and applied to raw EEG This correction procedure can be performed using Analysis Artifacts correction and Analysis Artifacts correction using templates commands At last case the artifacts related components are selected automatically using criteria of similarity to predefined artifact topo
276. rect fields show number of trials when the patient performed the task incorrectly Task performing correctness is controlled by monitoring button states according to Subject Response Processing parameters Number of trials treated as artifact 1s displayed in the Artifact fields Artifact Processing The following parameters are used for automatic artifact analysis and elimination 224 Level set threshold value in uV An EEG interval trial is treated as artifact if an ERP absolute value for any channel and for any bin exceeds Level value Channels define channels to be processed for artifact analysis Possible options are All process all channels Only EEG process only EEG channels Only Bio process only Bio channels Table the defined channel table 1s used and Level value is ignored Don t Reject artifacts are not eliminated Use the Threshold for channels button to define a list of channels to be processed and individual threshold values for artifact analysis This button calls Artifact Rejection Thresholds dialog Synchronization Several stimuli are allowed to be presented during one trial Also pre and poststimulus intervals may change from trial to trial even if trials belong to one averaging group In this case it 1s necessary to set additional parameters to synchronize trials correctly when averaging them Moreover some tasks may need analyzing ERPs preceding the response reaction Type select trial s
277. rform this task use Edit Copy command The waveform areas visible in the EEG window will be copied to clipboard and can be then pasted into final report text or into any application WinWord Paint etc window by means of Edit Paste command 5 Selecting an interval for processing To select an interval use vertical markers Place the cursor on the time scale of the active window the cursor should change its form to Clicking the left or right mouse button sets the corresponding left or right marker The time scale for selected interval will be highlighted in color Marker position can be changed by means of the mouse Place the cursor on one of the markers the cursor should change its form to Then drag cursor with left mouse button pressed Marker position can also be changed using keyboard Press Shift Left Right arrow keys to move left marker Press Ctrl Left Right arrow keys to move right marker Press Ctrl Shift Left Right arrow keys to move both markers simultaneously 6 Printing an EEG interval To print an EEG interval use File Print and File Print Preview commands 64 7 Deleting an EEG interval You may need to delete an EEG artifact interval To delete an interval select it and use Edit Clear command This command can be used to delete a part of video data only but EEG data will be kept Edit Clear command to mark artifacts time interval is the better ideas D Attention Usin
278. rocessing 44 3017 3030 Comon P 1994 Independent component analysis a new concept Signal Processing 36 287 314 Jutten C and Herault J 1991 Blind separation of sources I An adaptive algorithm based on neuromimetic architecture Signal Processing 24 1 10 that exploit independence to perform blind source separation ICA algorithms can separate complex multi channel data into spatially fixed and temporally independent components whose linear mixtures form the input data records without detailed models of either the dynamics or the spatial structure of the separated components The Infomax algorithm was implemented in EEGLAB software Delorme A Makeig S EEGLAB an open source toolbox for analysis of single trial EEG dynamics including independent component analysis Journal of Neuroscience Methods 2004 Vol 134 pp 9 21 and successfully applied for both analysis of independent components of EEG ERP for review see Onton J Westerfield M Townsend J Makeig 5 Imaging human EEG dynamics using independent component analysis Neuroscience and Biobehavioral Reviews 2006 V 30 P 808 822 and for artifacts correction procedures Delorme A Sejnowski T Makeig 5 Enhanced detection of artifacts in EEG data using higher order statistics and independent component analysis NeuroImage 2007 V 34 P 1443 1449 This Infomax algorithm was implemented in WinEEG software for analysis on raw EEG and ERPs WinEEG program p
279. rovides following possibilities 1 The spectra of EEG independent components The spectra of EEG independent components are computed for selected time interval Multi channel raw EEG 1s decomposed to independent components Than power spectra are computed separately for each independent component similarly described above The single spectra average spectra and component topographies are displayed in ICA window and are available for analysis Following diagram illustrates consequence of processing and analysis steps 48 ICA spectra analvsis functional diagram Spatial High order Montage filtering Bandpass bandp processing artifacts filtering FIR filtering correction EEG datafile Calibration m Concatenate Decompose Compute Artifacts artifacts independent j to elimination free independent component epochs components spectra Database of observations ICA window Computing and analysis independent components spectra The command Independent component spectra from menu Analysis runs this procedure 2 Single trial independent components analysis of ERPs The independent components of ERPs are computed not for whole EEG file but for specified time intervals beginning after selected time events stimulus in the trials This time intervals are merged to continuous time series and corresponding multi channel raw EEG is decomposed to independent components ERPs are computed separately for each ind
280. rs But in this case you should change them in WinEEG program also see Setup Equipment configuration command 2 Testing the synchronization of computers 4 Perform Switch to Slave Mode command of PSYTASK program 5 Perform Analysis Stimuli Presentation Programs command of WinEEG program 6 Click Update button If synchronization COM ports are defined correctly the progress bar will display a process of transferring of task protocols from PSYTASK program to WinEEG program Otherwise WinEEG program will report that the slave computer doesn t respond 7 Change the COM ports and their parameters if it is necessary using Modify Synchronization Parameters command of PSYTASK program and Setup Equipment configuration command of 43 WinEEG program and perform 4 7 steps It is necessary to find correct combination of COM ports Attention It is necessary to perform steps 4 6 every time when the list of tasks or their A parameters is changed in PSYTASK program Attention PSYTASK program is able to send correct task protocols Please be attentive and check newly added task protocols before updating list of protocols for WinEEG program Carrying out of ERP studies 1 Place the electrodes on the patient s head For a normal investigation 19 electrodes are placed using the International 10 20 system Also a common point electrode N electrode and reference electrodes must be placed bipolar or monopolar montage 15 u
281. rtifact related signals Long term artifacts can be constantly removed from EEG recording Following steps should be done to remove artifacts 1 Find the time interval including artifact related signals by visual inspection 2 Select the time interval using vertical markers see Chapter 15 7 7 3 Run command Clear from menu Edit WinEEG software will remove selected time interval from EEG recording and length of EEG file will decreases This method of removing artifacts related time interval has some disadvantage The additional artifacts related to transient response of band pass and notch filters in EEG recording parts joint time moments Another manual procedure does not remove artifacts related time intervals from EEG recording but marks it only These time intervals will exists in EEG recording but will be eliminated from processing 35 during EEG spectra wavelet band power wavelet coherence and independent components computation Following steps should be done to mark artifacts 1 Find the time interval including artifact related signals by visual inspection 2 Select the time interval using vertical markers 3 Run command Cut from menu Edit The time interval will be marked by horizontal blue bar placed on the bottom of EEG window Marked time interval can be recovered The automatic artifact detection procedures base on comparison of any parameter of EEG signal with defined threshold If this pa
282. s Main Toolbar Keys CTRL P 20 File Page Setup command Set the print page parameters The Page Setup dialog is displayed on calling this command 21 File Print Preview command Use this command to display the active document as it would appear when printed When you choose this command the main window will be replaced with a print preview window in which one or two pages will be displayed in their printed format Use print preview control bar for detailed preview Shortcut Main Toolbar 14 22 File Print Setup command Use this command to select a printer and to set printer options The Print Setup dialog box is displayed on calling this command 23 File 1 2 3 4 commands Use the numbers and filenames listed at the bottom of the File menu to open any of the last four documents you have been working with 24 File Exit command Use this command to end your WinEEG session Shortcuts Main Toolbar 5 Mouse Click icon in the right upper corner of WinEEG window n Double click application icon in the left upper corner of the WinEEG window Keys ALT F4 112 25 Undo command Undo last change in the final report Shortcuts Main Toolbar Keys CTRL Z ALT BACKSPACE 26 Edit Cut command Mark selected time interval of EEG record as artifact ff EEG window 1s active Cut selected text to the clipboard if Final report window is active The command
283. s Bandrange filter using For EEG Window Opens a final report Inserts patient card into final report text Inserts a final report template into final report text Display signal parameters table Opens an EEG Mapping window Calculates EEG indices for a selected interval Calculates EEG power spectra and the coherence function for a selected interval Calculates EEG power auto and cross correlation for a selected interval Calculate and display hide spectra density arrays in EEG window Runs LORETA application and store to it the voltage data corresponding to position of vertical markers Runs LORETA application and store to it the EEG power covariance matrix computing for selected time interval Run BrainLock program optional Run utilities for nonlinear analysis of EEG optional Start automated spike detection procedure Calculate averaged spike waveforms and open ERP window Correct electro oculogram artifacts caused by eye movements from the record Mark EEG artifacts Correct EEG artifacts by spatial filtering of raw EEG or recover previous correction The artifact components are selected manually Correct EEG artifacts by spatial filtering of raw EEG The artifact components are selected automatically by similarity component topographies to predefined templates Turn on off band pass filter defined by Setup EEG bandranges command Compute Compute Compute Compute Wavelet
284. s or condition with the simplest estimation of statistical significance of differences 21 Batch data processing It helps to compute a lot of different spectra ERP ERD automatically and etc Artifacts Artifacts Automated Other EEG file detection and spikes related marking Mom atom detection processing Playback Import data ASCII file EEG datafile Export EDF file Data aquisition Spectral spectra Database of analysis file spectra Database of observation Event related ERP Database of potentials file ERP Independent component analysis Database of processing result Other data Data processing file Data flow functional diagram 4 Composing a Final Report To create a final report WinEEG has a built in window text editor with standard text functions including block operations The patient card 1s automatically added to the report There 15 also a help menu enabling automatic inclusion of standard formulations in the text The final report can be prepared using MS Word Both the patient card and pictures and tables of processing results can be inserted into final report text 5 Printing EEG Fragments Processing Results and Report Text WinEEG enables high quality graphic printing of EEG signals and processing results on many of the most popular color or black and white printers When printing EEG signals absolute horizontal and vertical scales paper speed mm sec and se
285. s case the EEG will displayed in upper parts and position of all founded spike will be output in lower part by vertical bars The horizontal scale 15 selected thus as the whole array of spikes can be displayed in lower part The left and right border of track button of scroll bar will correspond to first and last displayed EEG sample They will correspond to first and last displayed spike s mark also This relationship between track button displayed spikes array and displayed time interval at upper part will help to find a part of EEG required for analysis 68 24 Manual changing spike parameters The automated spike detection method can miss real spikes and mark some artifacts To correct results of automated spike detection method commands Add Spike and Delete Spike could be used To add spike move mouse pointer to appropriate channels and time sample press and release right mouse button and choose command Add Spike from pop up menu To delete marked as spike artifact move mouse pointer to appropriate spike label press and release right mouse button and choose command Delete Spike from pop up menu To change main channel of spike defining a localization of spike source move mouse pointer to appropriate spike label press and release right mouse button select command Change Channel in pop up menu and choose appropriate channel from additional menu 25 nsert spike waveform into report To insert waveform of selected spike into cli
286. scs 28 6 MAINTAINING EEG DATABASE AND PROCESSING RESULTS 0scceccsececcecceccccccscceccescsceccescesccsscsscescscescescesscsscsscscesceees 29 COUT CK START iini oido 0308129 128100099 00010 2010809902050 1092001090085 30 DATA ARCHIVING a iesece seeve suvekvevesse vu vec e covevse ve sve qvv dev eee EN QE VE Fede E EE YE SEL EN e MEA VEEROETEL EVER NEC R EA V RE EV VE Fa de 31 DIGITAL EEG EIELTERING iet eetuv euo netu Y CY ve EXER OR FERE CET EE CE edv CERE CE eer 32 ELECTROOCULOGRAPHIC ARTIFACTS CORRECT ION eee 32 CORRECTION OF ARTIEAC TS iie evt ei eee eoe Ev eue peo ovv e a ese peu e boil ee v dvi v dE ae eve vai va 34 AUTOMATIC AND MANUAL ARTIFACTS ELIMINA TION ccccccsccscccsccsccccccccccccccccccccccccccccscccsccccccccccccccsccoes 34 EFEGINDICES aut pede eO eo v eed Decus es LOL UL E 35 EEG 37 EVENT RELATED POTENTIALS ve Po e Rr e svi oe db Ee 39 EVENT RELATED EEG DE SYNCHRONIZATION AND 40 WAVELET ERP
287. sed If EEG 15 assumed to be recorded in reference to ears two reference electrodes are placed on the ears A reference electrode can be placed on the forehead and connected to Al or A2 input the appropriate electrode is provided in the set and a corresponding montage 15 set in the program EEG signal quality depends on paying special attention to the placement of common point and reference electrodes Attention Common point and reference electrodes are to be placed in any case whether 2 Connect the electrodes to their respective inputs on the front panel of the amplifier block 3 Set the electrode impedance checking mode using Recording Impedance command If the impedance value is satisfactory less than 5 kOhm close the Control of Electrode Impedance dialog Otherwise re install those electrode s showing excessive impedance 4 Run the File New command Fill in the patient card choose a montage and check it When these actions are completed successfully a new EEG window will be displayed on the screen 5 Run the Recording EEG Monitoring command Visually check the quality of the live EEG displayed in the new window If any channel is acquiring EEG poorly re install the corresponding electrode s Check EEG acquisition quality using a monopolar montage without averaging 6 Run the Recording EEG Recording command to start recording signals to a file 7 Run the stimuli presentation program using the Recording Stimuli Pr
288. selected format parameters see Setup gt Graph Formats command Maps are placed below graphs Average Displays average band power graphs for wavelet ERP bandpower analysis Rasters Displays time frequency rasters for wavelet ERP analysis Time Frequency Use the Scale list in the ERP bar or and keys of keyboard to change color scale sensitivity or Y axis scale for graphs 84 Choose graph or map size from the Size list in the ERP bar Use Active group fields in the ERP bar to set start and end time of the interval to be depicted by ERP graphs Use Maps group fields in the ERP bar to set start and end time of the interval to be mapped and also to define degree of ERP compression If the Step parameter value exceeds quantizing interval then time averaged ERPs will be mapped Use Baseline group fields in the ERP bar to modify interval for baseline calculation Use Active Groups group fields in the Averaging group bar to choose groups to be displayed and to select an active group Use Averaging bandrange group fields in the Averaging group bar to set frequency band for displaying average band power graphs for wavelet ERP analysis Use Setup Mapping Style command to change color scale palette and map appearance Use Edit Copy command to copy graphs or maps visible in the window to the clipboard They can then be pasted into final report text or into any application WinWord Paint and etc window by m
289. signal amplitude 1 e square root of power The amplitude term has physical sense only for spectral graphs in all other cases it means square root of the total signal power in a given frequency band Color scale encodes amplitude in regular intervals Measurement units microvolt Graphs Y axis shows percentage of total broadband signal power 15 a particular frequency band Color scale encodes power percentage in regular intervals Measurement units percent Log P Graphs Y axis shows logarithm of signal power Units For coherence and auto and cross correlations Grad For phase Use the Fill By list disabled for auto and cross correlation to choose how to fill areas under a graph or a histogram None Blank white areas Bandranges Fills areas by colors defined in the standard frequency band parameters see Setup EEG Bandranges command Color Scale Fills areas by color scale showing power level Choose graph or map size from the Size list Use Normalization fields disabled for auto and cross correlation to define frequency band used for computation and displaying normalized spectra see above Value 90 These parameters will influence on results of statistical comparison of two spectra see Analysis Comparison of results command Use Statistics field disabled for auto and cross correlation to show or hide results of statistical comparison of two spectra The statistical significance of
290. spatial filter Attention The processed part of EEG record should include both the artifacts signals and the artifacts free EEG signal to have a possibility to estimate their components Attention The algorithm of artifacts correction is not ideal That is why the visual inspection of results of correction 15 necessary If the results are not satisfied another time interval should be selected and analyzed Attention The correct usage of this method 15 possible for fixed parameters of EEG montage and band pass filters That is why any changes of mentioned above parameters will automatically disable artifact correction spatial filter gt gt gt Shortcut Main toolbar 126 105 Analysis Artifacts correction using templates command Run this command to correct EEG artifacts by spatial filtering of raw EEG The artifact components are selected automatically by similarity component topographies to predefined templates The Artifacts correction using standard component topographies as templates will be displayed on calling this command 106 Analysis Turn on off band pass filter not in a menu Run this command to turn on off band pass filter defined by Setup EEG bandranges command Press right placed arrow button to displayed pop up menu helps to select filter Shortcut Main toolbar 107 Analysis Compute ERP command Calculates event related potentials ERP for a selected EEG interval in the activ
291. stop 73 0 Hz 384 m Define frequency limits filter type and order For Chebyshev filter type also select low and high frequency cutoffs Filter Response Function Impulse Response and Filter Response graphs help to check if filter parameters you enter are adequate 263 107 Graphics Page Format dialog Graphics page format Standard size Width mm i AL Height mrn zl Change AMES Calibration Ive X Step of tip marks ms 200 Left mm mm E Step af tip marks nV 2 Width mm Height mm 1 Waveform graphic line parameters For groups ian Cures list 1 34 zb NI sari lt Gree Gra lt Grd gt Jo de zb z sare Grd 4 En zb 21 Fe lrl gt sargs 4 24 ef zb 21 Bri lt 3 gt lt arg gt 63 Zi 26 21 Fe Gras b HH Er zb 21 FA Gris sargs 7 ef zb 21 Bri lt Grd gt B 4 AL zb 21 Gr carte d 24 AL zb 21 Ca lt Grl gt Gr s sara Bids Ll 1n Rh Ce Gras efr a Cancel Change fram Name Choose a format from list or enter a new name for current format Page Size Press Change button to s
292. t Montage Format Menu Commands Toggles display of Main toolbar Input Control toolbar Analysis toolbar maps of two EEG instants selected by Left and Right cursors dipole source localization of two EEG instants selected by Left and Right cursors Filters bar Maps bar in an EEG mapping window Spectra bar in a spectra window Indices bar in an indices window ERP bar in an ERP window Biofeedback bar in a biofeedback window Calculator ratio formula bar in a spectra window an indices window or a biofeedback window Averaging Group Bar in an ERP window Modifies Customize MainToolbar button set Modifies Input Control toolbar button set Modifies Analysis_toolbar button set Shows or hides the status bar Shows or hides the Channel Names bar Show hide Video Window for main video camera Show hide Video Window for additional video camera Change a size of Video window Decrease vertical scale in an EEG window Increase vertical scale in an EEG window Decrease horizontal scale in an EEG window Increase horizontal scale in an EEG window Chooses or modifies a montage channel list filters gain color electrodes etc The Format menu offers the following commands Font Paragraph Recording Menu Commands Chooses a font Formats a paragraph The Recording menu offers the following commands EEG Monitoring Starts resumes EEG monitoring without recording data to the
293. t3 menu4 go 5 Option insert text4 menu4 quit we Option insert texti menu5 next Option insert text2 menu5 break Option insert text3 menu5 Option insert text4 menu5 quit Option ODIO TODUCrOnn TODUSXOn TOPCON THSere insert ITNSert insert insert insert insert insert text of titleo COSLA texts text4 textl text text4 7 next break go Menu quit next break go Menu GULLE menu Menu title text of tities IDnserc insert insert insert texkl text4 2H menu menu menu menu goblock Block3 next goblock Block3 break goblock Block3 go Menu9 GODLOCK BLOCKS Quit Optionl menu amp Option menus option Options Option Option4 menu amp Option end menu 9 title Optionl menu9 Options 9 Options menu9 Option4 menu9 end endblock menu 10 title Optionl menulO TODCIOnz Options 10 Option4 menulO end menu 11 Optionl 11 Option2 11 Options 11 Option4 11 end endblock 5 Limitations wee Option insert texti menu9 next Option insert text2 menu9 break
294. ta Phi fos m Fe 72 fice 72 so m reef 72 M iss M 36 o M 5 m Fe fre MW taf M i o fo 72 zie Mm Palas 225 s 270 m5 M 324 M or z 252 2 o fese 42 ch fao 270 Cag 126 Adeo Ad3 sn 162 fis Ads sn fise Ade sn 342 o p Biol Bint Ecg 4 Bind Iw Connect channels 41 and 2 Connect Channels A1 and A2 Check this option if you are not going to acquire EEG from different channels in relation to different ears or to the average ear If the option 15 checked and A2 nets are connected directly in the amplifier block so that there is no necessity to connect two electrodes to these nets or to use a jumper 151 7 Transformation Matrix for Weighted Average Referent dialog Change transformation coefficients if needed Transformation matrix for weighted average referent C4 a rJ Fol Foz FF F3 Fz F4 Fa T3 1 000 0 121 1 113 0 107 0 058 0 060 0 056 0 059 0 053 0 045 0 041 0 000 0 000 0 000 0 000 0 000 0 000 0 000 0 000 0 000 0 000 0 000 0 000 0 000 0 000 0 000 0 000 0 000 0 000 0 000 0 000 0 000 0 000 k 0 053 0 036 0 041 0 055 0 0
295. tabase OF Cancel 214 Load from database Press this button to load standard parameters of spectra computation compatible with normative database To define correct parameters press button Load from database and select corresponding condition from the list of conditions 66 Parameters For Event Related De synchronization Computation dialog To calculate ERD additional information on stimuli presentation structure in each trial 1s used together with source data To group trials by stimuli types or by response task trial labels are used These parameters are defined beforehand when creating editing stimuli presentation protocols by means of PSYTASK program installed on the presenting computer Parameters for event related desynchronisation computation Groups of trials Labels Correct Incorrect 2 ESL SUE 3 Eo i pompe qp L2 X Ca o Artifact Tit Group differences a 4 3 5 5 Choose Synchronization Stimulus Channels Stimulus 1 Thresholds for channels Button channel No Method Squared amplitude Time interval before ms lo Envelope Artifact processing Level LN Subject respance pracessing D efined Define Time interval after ms 0 vw Substract ERP from raw EEG Compression No Smoothing 25 Normali
296. tation The command 15 available only if anew EEG window is opened see File New command The Stimuli Presentation Program List dialog is displayed after calling this command Shortcut Input Control toolbar 82 Recording Turn On Off Music command Run this command to turn on off music for auditory biofeedback Shortcut Input Control toolbar 83 Recording Calibration command Run this command to review calibration of the amplifiers The Calibration of Amplifiers dialog will be displayed on calling this command Attention Amplifiers are calibrated by the manufacturer before metrological certification WinEEG users able only to view calibration results not to modify them Shortcut Input Control toolbar 84 Recording Impedance command Call the function of electrode impedance control Electrode Impedance dialog is displayed after calling this command 122 Shortcut Input Control toolbar 8 85 Recording Rewind Back command Run this command to rewind EEG window Shortcut Input Control toolbar K 86 Recording Playback command Run this command to play EEG window backwards Shortcuts Input Control toolbar 4 Keys ALT Left Arrow 87 Recording Play Forward command Run this command to play EEG window forward Shortcuts Input Control toolbar gt Keys ALT Right Arrow 88 Recording Fast Forward command Run this command to Fast Forward the EEG window Short
297. tch filter On the Filters bar choose an appropriate value from the Notch Hz list To change notch only for a selected channel hold Ctrl pressed Otherwise notch will be changed for all channels that are visible in the montage 17 Baseline offset On the Filters bar click up and down arrows of the Baseline field to change baseline To change baseline only for a selected channel hold Ctrl pressed Otherwise baseline will be changed for all channels that are visible in the montage 18 Adding or clearing user labels To add a user label run the Edit Add Label command or press Add Label button on the main toolbar and choose label type from the popup menu The cursor will change its shape to Place cursor at the desired position in the EEG window and click When adding a Channel or a Contour label its length can be adjusted by dragging and releasing the left mouse button To find a certain label use Find next left label and Find next right label buttons on the main toolbar To delete a label run Edit Delete Label command or press Delete Label button on the main toolbar The cursor will change its shape to Place it on the label to be deleted and click the left mouse button Attention After you have finished dealing with labels press the Add Label or Delete Label button on the main toolbar to return to default mode The cursor will return to its standard shape 66 19 Adding and excluding trials for ERP calculations
298. te dI 132 TAO COn MaN e MES ass 133 147 A alysis Rasters Tune Ereguency CoNIWand ais esent 133 SUS Posi dete ene cuu 133 149 Analysis Group THO Gon command DUE iD QN IDE EM 133 150 Analysis Export trial parameters command 133 151 Pop up menu ERP window Add Map 134 152 Pop up menu of ERP window Add Label 134 153 Pop up menu ERP window Copy Parameter Distribution command eese nnne 134 154 Pop up menu of ERP window Copy Channel 134 155 Pop up menu of ERP window Copy Channel to Report command esses enean nns 134 156 Pop up menu ERP window Source distribution LORETA 134 157 Pop up menu of ERP window Dipole source BrainLock command eese eene nnne 134 158 Pop up menu of ERP window Delete Labels 134 159 Pop up menu of ERP window Delete Labels and Maps commamnd esses nennen nenne 134 LOO Fane rE ard Con tQ aede duct iita denota cete tu atf ierunt 134 Analysis Genergied Mal COMMMGNG suot utei deo edel Bi dele t
299. ted according to montage parameters before processing ERD maps choose a monopolar montage for the active EEG window before calling this command D Attention EEG reformatted to a bipolar montage cannot be mapped If you wish to view Electrode coordinates are additional parameters for maps see Montage parameters Electrodes dialog Incorrect coordinate settings can disable mapping Shortcut Main toolbar 109 Analysis Compute ERCoh command Calculate event related coherence ERCoh for the active EEG file and opens an ERP window ERCoh can be calculated only if presentation of visual auditory was carried out synchronously with EEG acquisition After calling this command Parameters for Event Related De synchronization Computation dialog is displayed to define additional processing parameters Raw data 15 reformatted according to montage parameters before processing ERCoh maps choose a monopolar montage for the active EEG window before calling this command D Attention EEG reformatted to a bipolar montage cannot be mapped If you wish to view Electrode coordinates are additional parameters for maps see Montage parameters Electrodes dialog Incorrect coordinate settings can disable mapping Shortcut Main toolbar 110 Analysis Compute Wavelet command Perform wavelet ERP analysis for the active EEG file and opens an ERP window Wavelet power can be calculated only if presentation of visual auditory
300. ted as you need block Blocki menu Menul title ODE LOR VODELONZ ODECLONS Option4 end menul menur menu menul menu Menu2 Optionl 10 2 T ODE ODDS Option4 end menu title MODE On VODETONZ Option4 end menu 4 title ODLCTOnl PODC ONA Options Option4 end menu 5 title Optionl menu2 menu2 menu2 menu2 menu menus menus menus menu4 menu4 menu4 menu4 menus 1 2 5 l Option3 menus Option4 end endblock menus block Block2 menu Menu title TODELONL TOOCLONZ Option4 end menu6 menu Ond ODE DONE ODD TOMS Option4 end menus of titlel AnODtlomnm Insert menul next V Option insert text2 menul break U NOOETOR Insert Cexto menmul go Menus LOM toxta menur Guir Option insert texti menuZ next Option insert text2 menuZ break Option insert text3 menu2 go Menu4 Option insert text4 menu2 quit text OT Cile Option insert texti menu3 goblock Block2 next Option insert text2 menu3 goblock Block3 break Option insert text3 menu3 goblock Block2 go 5 Option insert text4 menu3 goblock Block3 quit Option insert texti menu4 next Option insert text2 menu4 break Option insert tex
301. the LORETA application the WinEEG program ask for a location of LORETA EXE file Its usual location is folder with name LORETA 020 MAIN 97 Analysis Spectrum power distribution LORETA command Run this command to call LORETA application and store to it the EEG power covariance matrix computing for selected time interval This command can be used together with Analysis Turn on off band pass filter to estimate the distribution of sources for EEG signal in the selected frequency band Before the first call of the LORETA application the WinEEG program ask for a location of LORETA EXE file Its usual location is folder with name LORETA 020 MAIN 98 Analysis Dipole Source BrainLock command Run BrainLock program optional 99 Analysis Nonlinear Analysis command Run special utilities for nonlinear analysis of EEG optional The Nonlinear analysis parameters dialog will be displayed on calling this command 100 Analysis Spike Detection command Run this command to automatically find spike waveforms in the whole EEG file The Spike detection dialog will be displayed on calling this command 125 101 Analysis Spike Averaging command Run this command to calculate average waveform of spikes and opens an ERP window The spikes will be sorted by main channel assigned with spike labels The Averaged spikes calculation dialog will be displayed on calling this command 102 Analysis Remove EOG command Run t
302. the components vau not want install Components w Program Executables 203815 95932 K Space Required 305518 Space Available 2096932 lt Back Next gt Cancel 9 Select components you want to install Don t install Sounds component if you don t plan to use auditory biofeedback Don t install Child Database component if you will not use Normative Database including spectra and ERP for children with the age from 7 to 16 years Press Next button to continue installation Select Folder x Setup will add program icons to the Program Folder listed below You may type new folder name select ane from the existing Folders list Click M ext to continue Program Folders BurndFree and BurndFree Toolbar Cluster Futuremark Guardant Developer s Kit 5 HJHOS4 Hewlett Packard x lt Back Cancel 10 Type a new folder name if you want Press Next button to continue installation 14 11 Wait for finish of WinEEG software installation Setup program will begin installation of Mitsar hardware drivers 12 Select English language from list as following 15 Setup Mitsar Drivers Welcome to the Mitsar Drivers Setup Wizard This will install Drivers 2 0 on your computer
303. the usage of additional parameters characterizing the spatial distribution of potentials for example equivalent dipole parameters can increase a specificity of detection method 57 1 D Flanagana R Agarwala Y H Wanga J Gotman Improvement in the performance of automated spike detection using dipole source features for artifact rejection Clinical Neurophysiology 2003 Vol 114 P 38 49 2 A Ossadtchi 5 Baillet J C Mosher D Thyerlei W Sutherling R M Leahy Automated Interictal Spike Detection and Source Localization in MEG using ICA and Spatio Temporal Clustering Clinical Neurophysiology 2003 submitted The amplitude temporal parameters using by WinEEG program are the following 1 Duration 1 defined as the time interval between two successive maxima or minima of an EEG wave Durl 2 Duration 2 defined as the time interval between two successive inflection points 1 e points where the absolute value of the first time derivative of the wave form has a maximum value of an EEG wave Dur2 3 Duration A defined as the time interval between the beginning and the pick of an EEG wave DurA Duration B defined as the time interval between the pick and the end of an EEG wave DurB Amplitude A measured from the beginning to the pick of EEG wave AmpA Amplitude B measured from the pick to the end of EEG wave AmpB Amplitude measured from the baseline zero voltage to the pick of EEG wave AmpZ Slope
304. the window content to clipboard Inserts the clipboard content at the current cursor position in the active document Deletes the selected block Selects the whole document Clears the whole document Clears all video data for active document Finds events in EEG record Finds a string in the text Finds one string in the text and replaces it with a different string Finds the EEG interval selected by left and right vertical markers Finds the beginning of an EEG fragment Adds a user label Deletes an existing user label Edits a patient card 101 Edits trial labels used for ERP calculation Adjust trial synchronization using synchronization signal recorded from Trial Labels Adjust trial synchronization special detector for example photodiode Change polarity Load Trial List View Menu Commands Change polarity of signals for selected list of channels Load trial list from ASCII file The View menu offers the following commands Toolbar Main Toolbar Input Control Toolbar Analysis Toolbar Maps Dipole Window Filters Bar Maps Bar Spectra Bar Indices Bar ERP Bar Biofeedback Bar Calculator Bar Averaging Group Bar Customize MainToolbar Customize Input Control Toolbar Customize Analysis Toolbar Status Bar Channel Names Bar Main Video Window Additional Video Window Video Window size Decrease Gain Increase Gain Decrease Speed Increase Speed Selec
305. tients birth for example from 01 01 1950 to 31 12 1959 To enable automatic search by date use DD MM Y Y Y Y date format Age from to step fields define a number of rows in resulting table Divide by gender box defines is the observations of males and females should be calculated separately or not 163 Press OK button for start a searching and calculation procedure The example of resulting table 15 placed below 17 File Open dialog Specify a file to open Files of Type File name Select the type of file you want to open EEG EEG file RTF final report file SPC EEG spectra file DX EEG indices file ERP event related potential file ERD event related de synchronization wavelet file ERC event related coherence file BEB biofeedback file And other types of file les 9 9 7 59 IM 13 69 I 19 69 f 01 A eeg eeg 13 44 eeg 19 44 14 02 69 08 69 14 59 20 59 f 02 A 08 A eeg 14 4 eeg 20 A 14 13 63 09 69 eeg 15 65 eeq 21 0 4 eeg H A s eeq 15 40 Beg 21 604 14 4 58 eeg 10 69 16 59 22 59 04 605 eeg 10 64 16 44 eeg 14 05 69 11 69 17 69 OSA 11 46 66g 174 144 06 69 12 18 9 19 404
306. ting system enables 100 safe data storage Moreover magnetic media are sensitive to damage by different external factors either mechanical or electromagnetic Operating systems and environments on a computer hard disk are even more sensitive given additional damaging factors such as computer viruses abuses hardware especially hard disk and software failures If you think your computer performance 15 stable enough don t rush to calm yourself Remember your friends and colleagues who have been working on a PC for a year or longer Do they ever complain that documents graphs tables or other data having taken plenty of time to obtain were lost or cannot be read You should listen to them because your unique experimental data from one time procedures or your own creative results 15 the most valuable information of all Modern computer technologies allow development of highly robust storage systems which are however very expensive to apply in medicine So data archiving duplication is the only way to save results of your work Remember also that the capacity of your hard disk 15 limited so sooner or later there will be no free space in which to continue working 50 in case we succeeded in persuading you that accurate archiving and duplication of EEG data 15 necessary and inevitable here are some words about magnetic media Of course copying EEG files to floppy disks 15 the easiest way but also the most expensive CD or DVD Wr
307. tion should be shown on the maps Draw isopotential contours Check if isopotential contours should be shown the maps 102 Names Of Fragments Trials dialog of fragments trials F3 Eyes Closed F4 Photestimul F5 Hiperventil Enter fragment names in the F2 F11 fields 259 103 User Label Description dialog User label description Mame Text Emo fverticalbar 0000009 Vertical label Eyes Opened Close Vertical labe Eves Closed Photo Photostimul Vertical label amit JHorizontallabel Artifact Spike Horizontal label Spike Slow Horizontallabel Slo Wave L m cem d TEE ii Cancel Use this dialog to define up to 10 user labels Name Enter label name to be included in the Label popup menu Type Select label type WinEEG uses 5 label types Vertical bar A vertical blue transparent bar without text Channel bar A horizontal blue transparent bar without text It highlights an interval within one certain channel Fpl Ref independent of its position in the window Label length 15 defined by the user when creating the label Channel contour A blue rectangular contour highlighting an interval within one certain channel Fpl Ref independent of its position in the window Label length is defined by the user when creating the label Vertical label A vertical
308. to Use the to the right of the name field to choose a drive and a folder 26 Export EEG independent components parameters EEG independent components parameters export is used for saving data in a file readable by other applications Folder pathname of independent components field displays the location of corresponding ICA files Use the Browse button to choose a drive and a folder Automatic excluding of components associated with artifacts fields group is used for definition of parameters of eliminations components related to artifacts Up to 6 different independent component topography templates can be used simultaneously for detection artifacts The additional parameters coefficient of similarity should be defined for each template Check Export first number of artifact free independent components only button to exclude low power independent components The number of components should be specified using Number of components for export field 177 Another criterion of excluding of low power components is the definition of total variance described by component This parameter can be entered in Percent of total variance described by first artifact free components with maximal variance Export parameters of independent components Folder pathname of independent component files EAQlesya b SECS Browse Automatic excluding of components associated with artifacts Eyes horizont
309. ts e Test whether channels are correctly defined or view another montage in the list see Montage parameters View dialog 178 Setup Fragment Names command Define list of EEG fragment names for Input Control toolbar Names of Fragments Trials dialog is displayed after calling this command 179 Setup Label List command Define up to 10 user labels for Labels popup menu User Label Description dialog is displayed after calling this command 180 Setup Photostimulation Programs command Define list of photostimulation programs Photostimulation Program List dialog is displayed after calling this command 138 181 Setup EEG Bandranges command Define a list of standard EEG frequency bands to be used for data processing in an EEG Indices window or in an EEG Spectra window EEG Bandranges dialog is displayed after calling this command 182 Setup Stimuli Presentation Programs command Display and modifies stimuli presentation programs protocols for ERP acquisition Stimuli Presentation Program List dialog is displayed after calling this command 183 Setup Graph Formats command Change graph output options in an ERP window Graphics Page Format dialog is displayed after calling this command 184 Setup Title command Define a running header to be printed at the top of each page for example your organization title Running Head dialog is displayed after calling this command 185 Setup Final Rep
310. ttom corner of the window The time scale colored by yellow indicates the signals which are really recorded to the disk Attention If window background is colored by red this means that batteries are low and you should change them as soon as it is possible 63 Use Record menu commands to manage EEG acquisition including start EEG monitoring and recording start stop video capturing pause and stop recording Note that these commands are available only for a new EEG file In other words you cannot record EEG into a pre existing file in the database To create new EEG file use File New command 2 Searching for an EEG interval To find a certain EEG interval use the scrollbar or keys Left arrow Right arrow Page Up Page Down To go to the beginning of a certain fragment use the View Find Fragment command To playback EEG or video EEG use the Record Rewind Back Record Play Back Record Play Forward and Record Rewind Forward commands The video frames are displayed synchronously with EEG scrolling in pop up Video Windows This window is shown or hided by View Main Video Window and View Additional Video Window commands Its size is changed by View Video Window Size command 3 Comparing two EEG intervals To perform this task first of all split the EEG window in two panes using Window Split command Then use scrollbars in each pane to find the intervals of interest 4 Copying window contents to clipboard To pe
311. ual inspection of results of correction 15 necessary If the results are not satisfied another time interval should be selected and analyzed 63 Artifact correction using standard component topographies as templates dialogue Artifact correction using standard component topographies as templates l x First word delimiter None Fragment nomm Eve blink average referent 19 n channels Similarity 0 800 Similarity Component number Component number o Similarity 0 Similarity 7 Component number o Component number 0 Similarity 0 Similarity 0 Component number 0 Component number 0 Number of iterations Cancel Use Fragment list to select EEG fragment that will be used for estimation of spatial filter 209 Use First word delimiter list to select delimiter of first word in fragment name This option is very useful if EEG recordings have different names of fragments but there is a common part at the beginning of one The topographies of components are placed below Check only those topographies for which corresponding components will be cleared for artifact correction Similarity specify the value of similarity for used topographies If all components have similarity of their topographies with template are lower this value WinEEG will report an error of processing Component number define number of components with maximal power that will be used for search
312. uat 135 162 Analysis Insert Final Report Template COIlWGhd ere et dee du Vu e eu ted i b dedo tuc 135 ttti vea fet iple ve aesti utt te t oe tu bt de ueni ied uitae 135 104 Analysis Select group Pairs Command T 135 e ole a 135 F66 Analysis Correct baseline Commands esi e et I UT NNI TAN I NE he 135 167 Analysis Save components filter command Se NH ci dob o v REIR du aes 135 100 filler command s eese tete ge e E b po tiep ette sts tias vend eI sa Ra NE Fo Lea EI 135 169 Analysis Export activation curves spectra 135 170 Pop up menu of ICA window Copy component 136 171 Pop up menu of ICA window Component name command 136 172 Pop up menu of ICA window LORETA for component eese ethernet eese 136 173 Analysis Export of component parameters 136 174 Setup Database Pathnames command i eese ee t a asd ATER 136 FTES TNE E 6 010111021177 BER RTT 136 MAP PIS CONNAN Pm 130 Ioe UP Montage
313. umans and its role in object representation Trends in Cognitive Science 1999 V 3 No 4 P 151 162 and detailed description the algorithm of wavelet coherence computation is present in R Saab M J McKeown L J Myers R Abu Gharbieh A Wavelet Based Approach for the Detection of Coupling in EEG Signals Proceedings of the 2 International IEEE EMBS Conference on Neural Engineering Arlington Virginia March 16 19 2005 P 616 620 42 Recording and analysis of ERP ERD ERCoh Wavelet Power and Wavelet coherence This chapter includes a brief description of method of recording and analysis of ERP ERD and ERCoh More information can be found in PSYTASK user manual and in the next chapters of this manual EEG window ERP window Analysis Compute ERP command Analysis Compute ERD command Analysis Compute ERCoh command Analysis Compute Wavelet command Analysis Compute Wavelet coherence command Stimuli Presentation Program List dialog Parameters For Event Related Potential Computation dialog Parameters For Event Related De synchronization Computation dialog Parameters For Event Related Coherence Computation dialog Wavelet Decomposition dialog Wavelet Coherence dialog Choose Group Differences dialog Artifact Rejection Thresholds dialog Subject Response Processing Parameters dialog Export and Import the data Batch data processing Select List of Channels dialog Results of Averaging And Subject Response Processing
314. un this command once more Shortcut Input Control toolbar 78 Reset DC Filter command not in a menu Use this command to reset constant component of the signal It can be necessary if extended band amplifiers are used Output potential of these amplifiers can contain a significant DC component as a result of motor artifacts or after electrodes are changed slowly returning to initial state The command is used to speed up the process of resetting amplifiers to initial state How to Run Input Control toolbar 79 Recording Photostimulation On Off command Use this command to turn rhythmic photo stimulation mode on or off The command 15 available only if a new EEG window is opened see File New command Use Input Control toolbar to change photo stimulation frequency 121 Photo stimulation frequency can also be modified by means of keys Ctrl Arrow Up Increases frequency by 1 Hz Ctrl Arrow Down Decreases frequency by 1 Hz Shortcuts Input Control toolbar Keys Blank 80 Recording Photostimulation Program command Use this command to turn a photo stimulation program on or off The command 15 available only if a new EEG window is opened see File New command Use Setup Photostimulation Programs command to set photostimulation program parameters Shortcut Input Control toolbar aly 81 Recording Stimuli Presentation Program command Use this command to start stop visual or auditory stimuli presen
315. y their length Minimal number of averaged epochs Define this parameter to automatically exclude EEG recordings with large amount of artifacts from future analysis 228 77 Select List Of Channels dialog Select channels to be depicted by graphs or maps in an ERP Window Use Select All and Deselect buttons to select or to deselect all channels Select list of channels Select all Unselect all Cancel 229 76 Results Of Averaging And Subject Response Processing dialog x 16 horizontal 14 16 2 0 0 0 47 0 0 16 vertical 29 19 B 2 0 0 65 0 0 0 24 horizontal 24 12 10 0 2 0 0 1 0 0 24 vertical 12 F 0 0 0 Bad 116 7 0 0 32 horizontal 14 B 8 1 0 0 513 0 44 3 0 0 32 vertical B 2 0 0 0 613 fo 0 0 40 horizontal 4 2 0 0 0 796 256 0 0 40 vertical B 2 0 0 0 11 0 112 0 0 0 Cancel The table of ERP averaging results consists of the following columns Group Name group names can be edited Total total number of trials of the given group in the source EEG data as result of trial label sorting Averaged number of trials used to average ERPs This value is obtained as result of subtracting Artifact Omission and Commission values from the Total value for the given group Error number of trials when the patient pressed incorrect button Omission number of trials when the patient should press the button in response to the stimulus but didn t do it Comm
316. y a protocol set in the PSYTASK program In this case one trial can present more than one stimulus Several different ERPs are calculated for different trial subsets To sort trials into subsets special trial labels arbitrary integer numbers are also set in the stimuli presentation protocol Artifact records are eliminated during ERP calculation For cognitive ERPs the patient response 15 also analyzed reaction time and percent of error are calculated separately for each trial subset Following diagram illustrates consequence of processing and analysis steps 40 ERP analvsis functional diagram Spatial Hish order Montaze Bandpass b 3 3 g enne andpass EEG datafile Calibration filtering ds En i correction Subject response processing Computing difference waveforms Artifacts Trials Trials elimination grouping averaging Database of observations ERP Database of window ERP ERP analysis Finally you can average ERP over a group of patients selected from the database Event Related EEG De synchronization and Coherence Event related EEG de synchronization ERD and event related EEG coherence ERCoh are computed similarly to ERPs see above ERD and ERCoh can be calculated only for EEG files recorded together with stimulus presentation by PSYTASK program on an additional stimulus presenting computer Below we describe the algorithm of ERD computation
317. y means of the PSYTASK program that it 1s to be installed on See PSYTASK User manual Press the Reread button to read a new file directly from the stimuli presenting computer connected to the EEG acquiring computer by an additional cable between their COM ports PSYTASK must run on the stimuli presenting computer in the slave mode Command line PSYTASK 5 Attention If any parameter of stimuli presentation in the PSYTASK has been changed the stimuli presentation program list should be updated otherwise ERPs will be incorrectly calculated Turn on EEG recording Check this option to start recording EEG to hard disk If the option is unchecked the data will be only acquired and monitored this mode can be useful for testing a stimuli presentation protocol or for training the patient 35 Update task list from slave computer dialog The dialog displays dynamics of reading task list from the presenting computer Press Cancel to stop reading the stimuli presentation program list The old list is not saved 183 36 Checking Impedance Of Electrodes Control of impedance of electrodes 40 kOhm kOhm 30 25 k hm 20 kOhm 15 10 3 EO hin kOhm impedance of electrodes means of color The color impedance scale is shown on the right Attention After every manipulation with electrodes transients take 1 2 sec to reach a new equilibrium 37 Calibration Of Am
318. ynchronization type Stimulus standard trial synchronization for ERP calculation Button trials are synchronized by the start of response reaction 1 by the moments when the patient s finger presses the button Spike trials are ignored Averaged sweeps are selected using spike detection information Subject response 1s not processed Stimulus set the synchronizing stimulus number for Stimulus trial synchronization Button Channel set the number of the channel acquiring button signal for Button synchronization Attention There are different modifications of buttons simple button one level button advanced button two levels button and digital button Setting of button channel depends on what type of button was used level signal should be used for simple button Both Low level and High level signal can be used for advanced button if the subject press both key during investigation The digital inputs Digl Dig2 should be used for digital button Subject Response Processing Press Define button to define or to modify parameters for subject response processing The Subject Response Processing Parameters dialog will appear Time Interval Before ms If the parameter value exceeds zero and the interval from the trial beginning the synchronizing stimulus see above exceeds this value resulting trial will be shortened from its start Time Interval After ms If the parameter value exceeds zero and th
319. your copy of WinEEG 196 Title Bar The title bar 1s located along the top edge of a WinEEG window a document window or a dialog It displays application name document name or dialog name To move a window or a dialog drag its title bar A title bar may contain the following elements Application icon in the left top corner of the application window for calling application system menu Document icon in the left top corner of a document window for calling document system menu Maximize button in the right top corner of a window Minimize button in the right top corner of a window Restore window size button in the right top corner of a maximized or a minimized window 140 Close button in the right top corner of a window closes document or application Application name Document name Dialog name 197 Scroll bars Scroll bar 15 placed at the right and bottom edges of a document window The scroll boxes inside the scroll bars indicate your vertical and horizontal position in the document You can use the mouse to scroll the document 198 Size command System menu Run this command to size the active window by means of arrow keys After the cursor shape has changed 1 Choose what window edge to move left right top or bottom by pressing a corresponding arrow key 2 Press arrow keys to move the edge 3 Press ENTER when the window reaches necessary size 199 Move command System menu Run this
320. zation for ERP calculation Button trials are synchronized by the start of response reaction 1 by the moments when the patient s finger presses the button Spike trials are ignored Averaged sweeps are selected using spike detection information Subject response 15 not processed Stimulus set the synchronizing stimulus number for Stimulus trial synchronization Button Channel set the number of the channel acquiring button signal for Button synchronization Attention There are different modifications of buttons simple button one level button advanced button two levels button and digital button Setting of button channel depends on what type of button was used level signal should be used for simple button Both Low level and High level signal can be used for advanced button if the subject press both key during investigation The digital inputs Digl Dig2 should be used for digital button Subject Response Processing Press Define button to define or to modify parameters for subject response processing The Subject Response Processing Parameters dialog will appear Compression The parameter is set in time readouts N and defines decrease of source EEG sampling frequency for ERP calculation A trial 1s divided into equal non overlapping time intervals N 213 time readouts long and average potential value 15 calculated for each interval The result trial will have N times less time readouts than
321. ze each trial Calculate statistical significance Iw Use as default 100 Load Cave from database Cancel Many fields of this dialog are similar to those of Parameters for Event Related Potential Computation dialog So additional fields are described below only Smoothing this parameter is set in time readouts N and defines filter sliding average width for ERD curve smoothing for each separate trial before averaging Method defines method for ERD computation Squared Amplitude Signal power 15 defined as square of EEG value 215 Envelope Signal envelope is computed by means of Gilbert transformation before power calculation Subtract ERP from raw EEG If this option 1s checked then before calculating EEG oscillation power ERPs will be subtracted from source data to eliminate their effect and only induced activity will remain Normalize Each Trial If this option 15 unchecked average signal power dynamics 15 calculated over all trials and then normalized by average signal power value for prestimulus interval Otherwise each trial 15 normalized separately Attention Check this option only if prestimulus intervals and intervals between trials are long enough not less than one second Otherwise prestimulus signal power variance will be very big and may significantly distort ERD dynamics 67 Parameters For Event Related Coherence Computation dialogue Parameters for event related coherenc

WinEEG User Manual - Bio-Medical Instruments, Inc.

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