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“Walk in” Modular Material Transfer Chamber Including Integration

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1. signal is reset When the VHP cycle completes the Start disinfection signal is reset Reset the Ready for disinfection signal Alarm Logic will be follows HVAC Loss of Start disinfection in cycle signal and Start Aeration signal not received Loss of Start disinfection in cycle signal less than 2 seconds after the Start Aeration signal is reset Timeout waiting for Start Aeration signal An alarm signal will be sent to the building HVAC in an event of a chamber or vapour generator critical alarm MAL Loss of Ready for disinfection signal and cycle not complete Timeout waiting for Ready for disinfection signal PBSC Ltd T 44 0 1484 354 500 Bradley J unction Ind Est F 44 0 1484 354 504 Page 19 of 20 TESO Leeds Road E info pbsc co uk Huddersfield HD2 1UR W www pbsc co uk Related Documentation either PBSC or BIOQUELL document formats as stated Specifications 1 Walk in FRS Functional requirement specification This document 2 Walk in product specification hardware PBSC document Factory testing documents 1 SAT Site acceptance test PBSC document Site testing documents 1 1QOQ Clarus L2 Bioquell document Chamber Mechanical Build sign off document PBSC document Chamber electrical test sign off document PBSC document Chamber commissioning document PBSC document Gassing cycle PQ Performance Qualification Bioquell docume
2. Walk in Modular Material Transfer Chamber Including Integration of a Bioquell Clarus L2 hydrogen peroxide vapour HPV generator PBSC Ltd T 44 0 1484 354 500 Bradley Junction Ind Est F 44 0 1484 354 504 Page 1 of 20 Leeds Road E info pbsc co uk Huddersfield HD2 1UR W www pbsc co uk Walk in chamber and HPV integrated system Product overview The Walk in HPV Materials Transfer solution is an integrated through the wall transfer device for material transfers between different classification rooms where either an air particulate clean up or material surface bio decontamination step is needed before transfer in either direction The Walk in requires a hydrogen peroxide vapour generator attached that can be connected either room side or in a separate technical area Inside view of chamber HPV Ceiling Mounted Aeration Unit Air Purge By pass System APB Stirring Fan tacho monitoring High performance inflatable seal door Internal Power Sockets and comms for Clarus Self Decontamination Stainless steel bumper rails to ensure product is 100mm from the wall for good air flow around the load Overview of integration of the Clarus L2 Hydrogen peroxide Vapour Generator Clarus L2 Hydrogen peroxide vapour Generator used with the Walk in transfer chamber must be possible to connect and operate either side of the chamber Loading or Unloading side Clarus L2 multi application H202 Vapour Generat
3. 6log hydrogen peroxide vapour HPV disinfection requirements overview Process and walk in chamber operation overview The walk in HPV chamber is a transfer device for through the wall material transfers between different classification rooms For GMP applications transfers can be bi directional between loading side GMP EU Grade D C and unloading side Grade C B or the reverse from the cleaner production side to the preparation side on the facility Interlocking direction priority is to be selectable In the case of GMP the priority is to be from the preparation side lower classification room to the production side higher classification room however the decontamination step should be selectable at the entry or exit side of the chamber For BSL Cat rooms exit decontamination will be the priority but it will also require bi directional decontamination interlocking In addition materials can enter and exit from the same side after a disinfection or air clean up cycle The walk in chamber has two principal modes of operation 1 Air cleanup cycle Timed particulate clean up with interlocked doors 2 Hydrogen peroxide vapour high level disinfection cycle disinfection of outer surfaces of materials placed in the walk in chamber for transfer The Air clean up cycle provides particulate clean up to EU Grade C B particle conditions as required via H14 grade inlet HEPA filtration The particulate clean up time is a validated time
4. and vapour generator PLC Digital Input and Output to Isolator PLC Digital Signal exchanges progressing to 1 Mode Walk in Chamber PLC Vapour Generator PLC Phase On disinfection selection Vapour Generator prepared for Disinfection configuration verification the disinfection and cycle status Mode Disinfection mode is set and a advanced at Vapour Generator selection Disinfection Start signal is UMI to Waiting for remote input cycle start provided to Vapour Generator On receipt of Start disinfection signal the Disinfection cycle advances to the first stage of acknowledge acknowledgement of cycle end Following the cycle end acknowledgement key operation a Cycle end signal is provided to the Vapour Generator 5 E Conditioning Conditioning of Temperature phase and Relative humidity Following completion of Gassing Conditioning phase the Vapour phase start Generator automatically and Run advances in Gassing phase At Gassing signal from Vapour At arrival of Gassing phase the Generator the GAS PRESENT Vapour Generator provides a display on the Walk in Gassing signal to the Walk in interface panel is illuminated PLC Amber i 2 On receipt of Aeration signal At arrival of Aeration phase Aeration the Air make up and exhaust Vapour Generator provides phase valves V1 V3 are opened with Aeration signal to Walk in PLC supply exhaust fans switched 3 s on followed the bypass valve V2 close
5. based on clean up from the actual environmental conditions on the loading or unloading side as specified Walk in chamber doors are required to have an inflatable interlocked function so that no two chamber doors are open at the same time The clean up is completed after loading before the other side door is provided access for opening Each time a chamber door is closed clean up will be completed automatically before re entry door opening is possible The chamber HVAC will remain in operation during standby to maintain room pressure balances The hydrogen peroxide vapour high level disinfection cycle Is an automated cycle for high level disinfection of material outer surfaces supported on point contact supports to maximise exposure before transfer between rooms PBSC Ltd T 44 0 1484 354 500 Bradley Junction Ind Est Fe F440 1489 354304 ees P DOCI Leeds Road E info pbsc co uk Huddersfield HD2 1UR W www pbsc co uk Type of vapour generator used with the walk in chamber The hydrogen peroxide vapour generator integrated with the walk in chamber for automated disinfection cycles will be the Bioquell Clarus L2 When a combined room and chamber function is specified the Clarus L2 and Chamber PLCs will require communication capability with an interface PLC controller If a Clarus C is required for a larger room suite application combined with a Walk in Chamber this is a different Chamber product and not covered by this sp
6. cycle Maintenance repair may be needed before continued use Any flow fault of the chamber aeration support systems Aeraflow or HVAC extract will be alarmed via flow failure as the vapour generator aeration phase time will not be valid In this event the vapour generator HPV cycle will be aborted with the vapour generator advancing to Off mode Maintenance repair may be needed before continued use PBSC Ltd T 44 0 1484 354 500 Bradley Junction Ind Est Fe E440 1489 334304 Cava i P DOCI Leeds Road E info pbsc co uk Huddersfield HD2 1UR W www pbsc co uk HPV cycle print record At each cycle phase transition key control parameters will be printed on the Clarus L2 printer Refer to the Clarus L2 User manual As standard the hydrogen peroxide gas concentration in the chamber will be measured and recorded on the Vapour Generator cycle print out Gas concentrations will be printed at phase transitions of Cycle start at Conditioning phase Start of Gassing phase Peak concentration in Gassing phase Start of Gassing Dwell phase Peak concentration in Gassing Dwell phase Start of Aeration Phase Peak concentration in Aeration phase At Aeration completion At cycle end acknowledgement Clarus L2 location and print records The Clarus L2 must to be possible to install and operate from a remote location from the chamber within specified restrictions A remote printer option is not required All print records
7. walk in chamber PLC are to communicate via a profibus connection and digital signals High level disinfection cycle qualification and control Outer material surfaces will be decontaminated before transfer via a validated 6log reduction using a hydrogen peroxide vapour sporicidal disinfection cycle Each HPV cycle will be developed based on defined load patterns and qualified with biological indicator challenges of Geobacillus stearothermophilus highly resistant spore form inoculation on stainless steel carriers presented in a Tyvek primary pack Gassing cycle development protocols are specified to complement installations at defined sites PBSC Ltd T 44 0 1484 354 500 Bradley Junction Ind Est Fe E440 1489 334304 rooe S orad P DOCI Leeds Road E info pbsc co uk Huddersfield HD2 1UR W www pbsc co uk Process and walk in chamber operation overview The high level disinfection process phases controlled by the Clarus L2 include the following steps PBSC Ltd 1 Conditioning phase reduction in relative humidity limited impact on process in small chambers and temperature conditioning of the vapour delivery system Gassing to process lethal conditions achieving saturated vapour conditions past dew point where hydrogen peroxide molecules are delivered to surfaces in a micron layer starting the oxidation process and free radical release to affect bio decontamination Gassing Dwell contact time of decontamination a
8. will be generated at the Clarus L2 It is likely to maintain control of the critical print records the Clarus L2 will not be installed in an uncontrolled technical area plant room but will be installed in the locality of the chamber Chamber HPV cycle temperature monitoring and control logic for out of specification deviations Temperature monitoring The vapour generator has temperatures that are controlled monitored and alarmed in the event of deviation during the HPV cycle Temperature control and monitoring includes the vaporiser refrigeration dryer and re heater temperatures and if outside set limits the HPV cycle will be aborted The chamber is fitted with a temperature sensor with default set point at 30 degrees C At arrival of the Max temperature set point during the HPV disinfection cycle the chamber PLC will monitor this condition for a set length of time 0 to set hold time In the event of the maximum temperature or above maintaining for the set time this becomes an alarm condition with an automatic abort of the vapour disinfection cycle and start up of Emergency Aeration The chamber APB will be automatically changed from by pass mode to aeration mode to reduce the chamber temperature The vapour generator will be aborted to Off mode Chamber pressure monitoring in the HPV cycle PBSC Ltd T 44 0 1484 354 500 Bradley Junction Ind Est te F440 1489 334304 page 1a ened P DOCI Leeds Road E info pbsc co uk Hudd
9. 0 1484 354 500 Bradley Junction Ind Est Fe E440 1489 334304 Page L201 A0 P DOCI Leeds Road E info pbsc co uk Huddersfield HD2 1UR W www pbsc co uk HPV cycle abort by emergency override Operators can abort a HPV disinfection cycle by actuation of an emergency override button one each side of the Chamber or by activation of the abort button on the Clarus L2 HMI Room HPV environmental monitor interface ATI room monitors monitoring for leakage at 1ppm can be interfaced with the vapour generator via a BMS building management system If activated this will abort the HPV disinfection cycle Cycle End following Emergency Aeration Following emergency aeration the operator will be prompted to take a gas concentration sample at a sample port provided on the chamber sample taken with an independent hand held gas sensor instrument device suitable for low level gas concentration measurement e g Portasens or drager peroxide tubes Following confirmation the chamber concentration is at or below the operator exposure limit of 1ppm one part per million for a time weighted average of 8 hours then acknowledging cycle end via push button Green light will advance the chamber status to open door access of the loading side only Maintenance repair may be needed before continued use Chamber fault conditions and recovery Gas mixing fans in the chamber have taco monitoring with failure an alarm condition that will abort the HPV
10. chamber package but a Paperless Yokohama DX100P is recommended BMS pressure monitoring port In some cases pressure differential monitoring of the Chamber in respect to adjacent rooms will be required Such monitoring will be the function of the BMS and not included in the chamber control system A pressure connection port is required in the chamber design in preparation for monitoring via the BMS if specified Air Clean cycle overview The Clean air cycle is a dedicated Air particulate clean up cycle only Chamber doors are interlocked to ensure the opposite side barrier door can not be opened until a valid air clean up cycle is completed expected to be just a few minutes specific times validated and set at time of installation Air Clean mode operation will be selected by way of a password protected setup screen on the user screen On closure of the selected door the validated air clean up Air purge will be automatically completed before permitting further opening access to either door When a door is requested to be opened the chamber ventilation switches to by pass The Chamber Display indicator is to illuminate Red if a chamber door is left open for longer than a preset access time PBSC Ltd T 44 0 1484 354 500 Bradley Junction Ind Est Fe E440 1489 334304 Page Ly or aD P DOCI Leeds Road E info pbsc co uk Huddersfield HD2 1UR W www pbsc co uk Signal exchange summary table of signals between chamber PLC
11. d Aeration On receipt of cycle complete At cycle complete time complete signal Walk in PLC verifies controlled by Vapour Generator and cycle exhaust flow status as alarm PLC signal provided to Walk in complete free and requests for operator PLC to acknowledge cycle End 4 On acer of cycle end signal Vapour Gen goes to Off mode After minimum of 10 seconds Vapour Generator proceeds to Cycle End remove Disinfection Start Off mode waiting for further HPV Signal cycles as required Clean door ee eee CE ae accesS ff Se provided PBSC Ltd T 44 0 1484 354 500 Bradley J unction Ind Es Leeds Road t F 44 0 1484 354 504 E info pbsc co uk Huddersfield HD2 1UR W www pbsc co uk Page 18 of 20 Material Airlock MAL to HVAC interfacing Start disinfection in cycle signal Output from chamber Alarm Signal Output from chamber Ready for disinfection signal Output from HVAC Start Aeration signal Output from chamber Note All signals are volt free contacts In cycle logic will be as follows Mal signals ready to Start disinfection and waits for Ready for disinfection signal from HVAC On Receipt of the Ready for disinfection signal the VHP Generator will transition through its cycle When the Aeration phase of the cycle is reached the Mal signals Start Aeration to the HVAC On completion of the Aeration phase the Start Aeration
12. ecification PBSC Ltd T 44 0 1484 354 500 Bradley Junction Ind Est te F440 1489 354304 POOE Dor ad TS Leeds Road E info pbsc co uk Huddersfield HD2 1UR W www pbsc co uk Overview of walk in chamber HPV integrated control systems Clarus vapour generators have dedicated siemens S7 PLC programmed for disinfection cycle control and alarm management of a pre defined cycle selectable from stored cycles up to 99 The Clarus L2 has an onboard User interface soft touch screen The walk in chamber requires a dedicated S7 PLC Programmed to control and monitor the chamber configuration and devices The devices include fans APB valves and pneumatics The PLC will alarm is the devices are faulty or running outside of set parameters Alarms and status functions will be detailed on the HMI A HMI will be located beside the load and unload doors In addition the walk in chamber temperature will be monitored and is required to have automatic emergency venting to cool the chamber load in the event of the maximum temperature alarm limit being reached during the cycle The user interface for starting cycles will be via soft touch buttons on the HMI An emergency override will be required at each side of the Chamber to abort cycles in the event of unacceptable deviation Safe recovery routines will be controlled in response to alarms or a cycle abort An emergency override is required inside the chamber The HPV Generator PLC and the
13. ent of unexpected leakage into either of the much larger volume adjacent ventilated rooms it should be possible to support by risk assessment and calculation that the Operator Exposure Limit OEL 1ppm will not be compromised in operation Door and valve configurations are to be monitored via positional sensors to assure HPV gas containment in cycle Based on safety considerations together with the fact that hydrogen peroxide molecules are subject to hydrogen bonding sticky molecules hence the vapour is poor at passive diffusion a pre gassing leak tests are not used at each cycle run Leak testing is completed as an operational qualification at installation and during routine environmental monitoring programmes A qualification leak test cycle is possible via the Clarus L2 controller The onboard pressure transducer of the Clarus L2 is used for the leak test control In this case the balance Filter sealing plates are fitted and a Leak test only cycle program used in the Clarus L2 from stored cycles PBSC Ltd T 44 0 1484 354 500 Bradley Junction Ind Est te F440 1489 354304 oe TS Leeds Road E info pbsc co uk Huddersfield HD2 1UR W www pbsc co uk Walk in Chamber system schematic Options Independent AHU 1 CV HEPA and extract fan 2 CV HEPA Catalyst and extract fan ll fee eal Q2 Airflow configurations include 1 Combined recirculation catalyst Aeration 2000 R range and APB 2 Co
14. ersfield HD2 1UR W www pbsc co uk The vapour generator has a pressure sensor transducer and will monitor and record chamber pressures through the HPV cycle In the event of low or high pressure alarms not expected the disinfection cycle will automatically abort Auxiliary power supplies inside the chamber During the HPV cycle process equipment may be part of the decontamination load In this case the process equipment may require power supplies single phase to run internal fan or ventilation systems to assure full decontamination Auxiliary power supplies are required from the Chamber control tower PBSC Ltd T 44 0 1484 354 500 Bradley Junction Ind Est te F440 1489 354304 Page 40 0120 TS Leeds Road E info pbsc co uk Huddersfield HD2 1UR W www pbsc co uk Optional independent temperature data logging The standard chamber system will include a facility for independent data logging of the chamber temperature with a 2 10 volt output signal for the purpose of independent data logging on a client supply data logger Optional independent hydrogen peroxide vapour gas concentration data logging The standard chamber system will include a facility for independent data logging of the chamber hydrogen peroxide vapour gas concentration with a 2 10 volt output signal for the purpose of independent data logging on a client supply data logger Recommended independent Data logger Data loggers are not included as part of the
15. f the unloading door is open there is no possible air exchange between the loading side and the unloading GMP Production or BSL side The unloading side door can be opened and closed as many times as required If the loading side door is opened a disinfection cycle must be repeated before the unloading side door can be opened The chamber display indicator on the soft touch screen is to illuminate red if a chamber door is left open for longer than a preset access time PBSC Ltd T 44 0 1484 354 500 Bradley Junction Ind Est F 44 0 1484 354 504 Page 12 of 20 ESO Leeds Road E info pbsc co uk Huddersfield HD2 1UR W www pbsc co uk Monitoring and HPV cycle deviation control HPV cycle critical parameter condition monitoring The chamber PLC controller is required to control and monitor all associated devices including fans valves door interlocks seal inflation and sensors including hydrogen peroxide vapour gas concentration flow and temperature The vapour generator PLC controls and monitors all critical control points of the disinfection cycle including monitoring only chamber pressure within set limits If any critical parameter or condition reaches alarm limits or settings during the HPV cycle then the cycle will automatically abort generator goes to Off mode At HPV cycle abort the chamber will be required to indicate alarm status Depending at what point in the HPV cycle abort occurred the chamber status must be co
16. gent for sporicidal activity This phase may include further hydrogen peroxide injection if required otherwise the injected peroxide will maintain in circulation Aeration re evaporation of micron layer of decontamination agent removal of gas residuals for a residue free process This is a joint phase with gas residual removal by the vapour generator catalyst 20 30 cubic metres per hour flow rate and a recirculation catalyst device i e a ceiling mounted aeration unit 2000 cubic metres per hour flow rate or the R range aeration units in conjunction with the APB 300 cubic metres per hour or building HVAC The chamber exhaust vent system may also include a catalyst filter if there is a restriction or safety case not to vent peroxide outside T 44 0 1484 354 500 Bradley Junction Ind Est F 44 0 1484 354 504 Page 7 of 20 TS Leeds Road Huddersfield HD2 1UR W www pbsc co uk E info pbsc co uk Chamber pressure regulation and maintenance of room to room pressure differentials during material transfers The APB will be running continuously with flow regulated by a local constant velocity damper Interconnection to the chamber exhaust duct may be rigid or flexible connection As required The inlet air fan will have a speed control facility for adjustment during set up to establish chamber pressure neutral relative to the defined reference loading side During gassing phases the APB will be diverted to By pass via a c
17. hange over valve system Pressure regulation of the chamber through consequential pressure changes due to temperature variation through the disinfection process is maintained by use of a Catalyst Hepa pressure balance filter This filter permits safe pressure release via a catalyst Hepa or pressure make up via a Hepa filter so that pressure in the chamber stays neutral with respect to the reference side of the chamber typically the lower classification loading side The pressure balance filter one single unit will have facility of connecting the pressure reference line to either side of the chamber specified for the defined application There is no automated Leak test required for Walk in chambers hence no valve on the pressure balance filter However installation and re qualification leak tests will be required and for these applications a manual valve is provided to close the leak path PBSC Ltd T 44 0 1484 354 500 Bradley Junction Ind Est te F440 1489 354304 tga e or ag P DOCI Leeds Road E info pbsc co uk Huddersfield HD2 1UR W www pbsc co uk Leakage management from the chamber Key safety considerations are that the chamber is always operated at neutral pressure with respect to the loading side and a very low passive pressure with respect to the unloading room side In addition door seals are inflatable with continuous integrity monitoring required Therefore there is very limited motive force for leakage In the ev
18. l connections required inside whilst maintaining cycle control from the chamber HMIs PBSC Ltd T 44 0 1484 354 500 Bradley Junction Ind Est Fe E440 1489 334304 aan ee P DOCI Leeds Road E info pbsc co uk Huddersfield HD2 1UR W www pbsc co uk Chamber HPV system functionality and control logic HPV Disinfection cycle overview At the arrival of the aeration phase there is an operational change to combined system aeration Aeration gas residual removal is completed by a combination of the APB or building HVAC A recalculating aeration unit Ceiling mounted aeration unit or the R range aerators may be used At the completion of the timed aeration phase reaching 1ppm or lower residual gas concentration the operator is requested to acknowledge the end of cycle To indicate an action is required by the operator the chamber status indicators on the touch screen flash amber and the cycle end acknowledge illuminates amber Transfer Mode After an HPV Disinfection cycle On pressing the cycle end acknowledgement button on the touch screen the indicator light goes out and the vapour generator unit is automatically switched off The chamber status indicator on the touch screen illuminates green and both door open access indicator lights are illuminated green The chamber ventilation will be running with the extract route through the chamber When a door is requested to be opened the chamber ventilation switches to by pass I
19. ll be selected by way of a password protected setup screen on the user screen The required Clarus L2 cycle can be selected from stored cycles and advanced on the Clarus HMI screen to waiting for remote input If both doors are locked and there are no alarms the HPV disinfection cycle can then be started by pressing the Chamber cycle start push button the push button will be illuminated green Door access will be disabled The chamber display indicator will illuminate amber The inlet air valves and extract valves will close isolating the chamber for receiving Hydrogen peroxide vapour The chamber air inlet fan will remain in operation with air re routed to extract via the by pass Gas mixing fans inside the chamber will be turned on Gas mixing fans require rotation monitoring in operation The vapour generator automatically progresses the disinfection cycle through the conditioning and gassing phases Over pressure in the chamber not expected due to pressure balance HEPA Catalyst will be monitored and if out of specification limits are reached the HPV cycle will be aborted and emergency aeration started Self disinfection of the Clarus L2 A function is required for self disinfection of the Clarus L2 As the L2 can be used for other room disinfections the L2 may need transfer into the clean room or containment room suite In the case the disinfection cycle is completed with the L2 inside the chamber with all HPV and contro
20. mbined recirculation catalyst plus building HVAC 3 Building HVAC only Air supply from 4 APB and R range aeration room units 1 Via chamber Hepa 2 Bypass Aeration 2000 mappene E Pressure ras 2 balance Hepa Cat o Gas mixing Fans 2 2 Walk In Transfer Chamber z Sensors e Temp RH I nflatable sealed nd interlock and interlocked e H202 A Catalyst unit run output signal is required from the Chamber control Tower Material transfer L2 Cart Vapour PBSC Ltd T 44 0 1484 354 500 Bradley Junction Ind Est F 44 0 1484 354 504 Page 10 of 20 Leeds Road E info pbsc co uk Huddersfield HD2 1UR W www pbsc co uk Chamber HPV system functionality and control logic HPV Standby overview In standby with both transfer doors closed with the APB unit air into the chamber is routed from the lower classification loading side through a H14 grade HEPA filter into the enclosure and around the chamber Chamber air is then extracted to the outside via a dedicated air handling unit Door open availability is indicated by an illuminated Green Door open push button on the soft touch screen The chamber status indicator on the soft touch screen is not illuminated in stand by HPV Disinfection cycle overview In HPV mode entry access to the opposite barrier side transfer door is only possible after successful completion of an automated HPV cycle HPV Disinfection operation wi
21. nt Summary Qualification report Bioquell document OL eS Manuals 1 Walk in user manual PBSC Bioquell document 2 Clarus L2 user manuals Bioquell documents PBSC Ltd T 44 0 1484 354 500 Bradley J unction Ind Est Fe KAT 0 1464F 394504 PROM ARELAS PESCI Leeds Road E info pbsc co uk Huddersfield HD2 1UR W www pbsc co uk
22. ntrolled for safe recovery to either hydrogen peroxide vapour clearance or a restart of a HPV cycle with successful completion HPV cycle abort generator goes to Off mode control responses 1 Cycle abort once cycle started at Conditioning phase e Chamber remains in set configuration with both doors locked and in alarm indication e To clear the cycle either a cycle end signal is provided by completing a valid Aeration only or HPV cycle selected from the HPV generator and re run or by emergency aeration via the chamber HVAC selected from the chamber HMI A chamber emergency aeration function will be available for selection at the chamber Emergency aeration via the chamber extract air handling unit only is direct venting of HPV to the outside environment for dilution and natural breakdown to water and oxygen The emergency aeration time is validated and pre set as a default value Alarm messages relating to the HPV generator will be printed with time date on the vapour generator printer During operation event messages will also be required to be displayed on the vapour generator HMI Alarm messages relating to the chamber devices position On Off status and conditions of flow and temperature will require display on the chamber HMI There will be no print out of chamber alarm events Refer to independent data logging option for temperature and Hydrogen peroxide vapour gas concentration via Yokagawa data logger PBSC Ltd T 44
23. or for chambers small rooms up to 75 cu m and isolators PBSC Ltd T 44 0 1484 354 500 Bradley Junction Ind Est F 44 0 1484 354 504 Page 2 of 20 Leeds Road E info pbsc co uk Huddersfield HD2 1UR W www pbsc co uk Overview of HMI integration The Chamber loading side will carry the master soft touch Siemens HMI with a slave on the unloading side All HMI screens including Clarus L2 1 Chamber 2 HMI be integrated into the Chamber master HMI At the Master cycle parameters can be changed together with all other functions At the Slave cycles can be selected run but not modified The HMI will replace push button features An Emergency override is required in addition to the HMI soft touch screen Airflow configuration options 4 optional configurations will be required see walk in chamber system schematic 1 2 3 4 Recirculation catalyst plus chamber Air Purge Boost system APB Recirculation catalyst plus Building HVAC inlet and exhaust Building HVAC only under control of BMS signal exchanges required during HPV cycle APB only Note Recirculation catalysts to include ceiling mounted aeration unit and the Bioquell R range Options 3 and 4 have the ability to run a R range aeration unit PBSC Ltd T 44 0 1484 354 500 Bradley Junction Ind Est F 44 0 1484 354 504 Page 3 of 20 TS Leeds Road E info pbsc co uk Huddersfield HD2 1UR W www pbsc co uk 2 0 Process and high level

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