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InterMED Viewer Interface User Manual - InterMED-Rx

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1. InterMED Rx InterMED Rx Request Viewer User Guide and Manual April 2009 Revision Sheet No 2009 04 05 2009 06 28 Modification for multisession version 1 0 390 a a TABLE OF CONTENTS The InterMED Rx Request Viewer eene nnn nennen 1 General Overview and Application Organization sessss 2 Application TABS Ji iisaasteneuin ex dua dere wa a nbn pul ra ved ad kl or A EE NDA RIA ee 3 Utility Bar desiderii uqE coa aded Coda en Sica valpuri iram iC cad adE riu a E LaR FM aS NNUS 4 Request Data Sectoid eos reca E vus a xh er dar aca aise asa XS P Y FRE 5 CONTERE SECHONS MMC 6 Interactions Table Section idee Reine dr edgacensss cee isa E E a eevee da dqre su ravi 7 Analysis Se Ction eee als 8 Manual Requests Section ied cae ea sid ansa a Ere kae ER Ea ax a DR eaa Rag R RR E Rae ga 9 Int rMED Rx Section Utility iiias iere eterne eene panne teh na a nn geass reip rax RR 11 Configuration Section Utility serwis si teed ree rin stad eua miren ie takes aa Pa XR IER x ert 12 Utility WIN OWS 2 DEL NERVES EN ERENRAREERRVESO SERRE PREIS UA ERREUR 14 Application EOGE zu 2e ve tne ai Varr dane dx Rae Orc vince OE Moda n aa LAT dx lara 14 The Reduest EISEs osakaxer de plex nadar are ane E Mcd a E na RU a os E E PARERE LA 15 Formulating a Pharmaceutical Opinion cessere 16 The InterMED Rx Request Viewer The InterMED Rx Request Viewer appl
2. 4 2009 04 05 07 50 51 AM 3 2009 04 05 07 50 49 AM 2 2009 04 05 07 50 47 AM 2 2009 04 05 07 50 45 AM 10 2009 04 05 07 50 43 AM 2009 04 05 07 52 19 AM 2009 04 05 07 52 17 AM 2009 04 05 07 52 16 AM 2009 04 05 07 52 13 AM 2009 04 05 07 52 11 AM 2009 04 05 07 52 09 AM 2009 04 05 07 52 08 AM 2009 04 05 07 52 06 AM 2009 04 05 07 52 03 AM 2009 04 05 07 52 01 AM 2009 04 05 07 51 59 AM 2009 04 05 07 51 57 AM 2009 04 05 07 51 56 AM 2009 04 05 07 51 53 AM 2009 04 05 07 51 50 AM 2009 04 05 07 51 49 AM 2009 04 05 07 51 47 AM 2009 04 05 07 51 45 AM 2009 04 05 07 51 43 AM 2009 04 05 07 50 54 AM 2009 04 05 07 50 52 AM 2009 04 05 07 50 50 AM 2009 04 05 07 50 48 AM 2009 04 05 07 50 45 AM 2009 04 05 07 50 44 AM Processed You may load a request by double clicking it or selecting it in the grid and clicking the Load Request button When the request is loaded it is first retrieved from the database then processed by the application and ultimately displayed in the Interactions Table and Analysis sections of the main application window which will be brought to the foreground Formulating a Pharmaceutical Opinion Please note At the moment you may formulate opinions ONLY for interface requests that incorporate patient data The Viewer Application can be used to emit Pharmaceutical Opinions Pharmaceutical Opinions are used to convey prescription modifications to the concerned health professionals and or organisms To a
3. The edit box will contain the text of the opinion You may consult but not modify the text Alternatively you may copy paste the text into a text editor and modify it as needed Use the Print button to render the opinion and close this window Use the Cancel button to close this window without rendering the opinion
4. new request for analysis InterMED Rx Client Interface 10 00 mg MANUAL REQUEST MED GRID Add Update Button The caption of the button toggles between Insert and Update according to the value of the Medication pull down If the med in the Medication pull down is already in the grid then the caption will be Update otherwise it is Add sqsanbay jenuew xy a3Wa7U1 merema mee aa uoneanDijuo e posee _ This instance of the utility bar contains the usual buttons and as well as a Load and a Send button which can be respectively used to load the medications of the loaded request and send the request for analysis By clicking the Load button the meds of the currently loaded request are loaded into the manual request med grid This is especially useful if you want to adjust dosages or meds of an interface request and resubmit it for analysis By clicking the Send button the meds configured in the request grid are sent for analysis The result is displayed ass soon as they are received A 30 second timeout is in effect for the operation after which a message is displayed and normal operation is resumed i e if the request is not answered within a 30 second period it is considered that the request has failed and needs to be re submitted The manual request section itself is made up by a medication grid a medication pull down fields to specify the dose and dose unit as
5. bar When the application is locked only the InterMED Rx Authentication window shown below is visible To unlock the application enter the password that was entered in the Password field of the Configuration section If the password has not been set then it is intermed by default The password is case sensitive and is reset to default when the application is started InterMED Rx Page 14 The Request List The InterMED Rx Request List window is used to load requests that have been initiated by the current user determined by the network domain username in the past It is accessed by clicking the Request List button on the utility bar of the main application window Request Patient Meds Request Date Date Reponse pat 2 pati pat 0 pat 0 pat 3 pat 2 pati pat 0 pat 0 pat 3 pat 2 pati pat 0 pat 0 pat 3 pat 2 pati pat 3 pat2 pati pat 0 pat 0 pat 3 I lt Load Request JA 2 2009 04 05 07 52 19 AM 10 2009 04 05 07 52 16 AM 5 2009 04 05 07 52 14 AM 3 2009 04 05 07 52 12 AM 2 2009 04 05 07 52 10 AM 2 2009 04 05 07 52 08 AM 10 2009 04 05 07 52 06 AM 5 2009 04 05 07 52 04 AM 3 2009 04 05 07 52 02 AM 2 2009 04 05 07 52 00 AM 2 2009 04 05 07 51 58 AM 10 2009 04 05 07 51 56 AM 5 2009 04 05 07 51 54 AM 3 2009 04 05 07 51 52 AM 2 2009 04 05 07 51 50 AM 2 2009 04 05 07 51 48 AM 10 2009 04 05 07 51 46 AM 5 2009 04 05 07 51 44 AM 3 2009 04 05 07 51 42 AM 10 2009 04 05 07 50 53 AM
6. ccess the Opinion window you must first select the analysis for which you want emit an opinion by checking its checkbox in the Analysis section and clicking the Prepare Opinion s button from the Utility bar E InterMED Rx Client Interface AARI p AT 3 a dH Opinion for analysis 43 E3 Analysis text as rendered in the ena a Analysis section ribetsgy Md 0 0 e ffi for o e Recommendation pull down ares stl fs Saet wil peto cvesA 3 The value of this pull down determines the comfiguration o 2 of the remaining formulation isoenzyme fields r However due to s interaction but rudent to lower the siskyeuw aqel LI Emit to Md 1 1 lug drug interactions Comment space a in vitro studies Iv paso r r ee df ld Prepare opinions lt uope4nbyuoo xe Q3iiequr l sqsanbay jenuew Request List oe Formulating an opinion is accomplished by entering information in the text fields and making the appropriate choices from the pull downs provided Note that the pull downs and text fields are configured dynamically according to the value of the recommendation pull down All fields except the Comment are mandatory Once you have finished formulating the opinion you may preview it or emit it by respectively clicking the Preview or Emit but
7. ck Button Used to lock the application The currently configured password must be used to unlock the application If the password has not been configured it is intermed by default 2 Request List Button Used to access and load requests launched from the workstation Please refer to the Request List Window section of this document for further details on loading requests 3 Request Refresh Reload Button Used to refresh the currently loaded request when the Request Data and Content Section are not synchronized Request Data Section As specified above the request data section is responsible for exposing patient data request stats and medication data The following subsections are available Patient Data This section presents patient related data as it would have been sent by the Interfaced Patient Management Application Please note that this data is only available for interface requests Request Stats This section presents various request properties and statistics such as request dates source language med count and interaction counts Medication Data This section presents request medication data Each request medication will have its own section exposing the medication name dosage and prescribing physician Please note that the prescribing physician is only available for interface requests Content Sections The content sections are directly associated to the selected tab Each content section is de
8. ently loaded request Please refer to the InterMED Rx web site for instructions about interpreting the interactions table Please note that you must have an active web site account to access this information Analysis Exposes the performed analysis results for the currently loaded request Please refer to the InterMED Rx web site for instructions about interpreting the analysis Please note that you must have an active web site account to access this information Manual Requests Allows the end user to send manual requests for analysis Manual requests can be derivations of the currently loaded request or newly formulated requests InterMED Rx Exposes an embedded web browser that connects to the InterMED Rx web site when selected Please note that the workstation must have access to an active web connection for this section to perform correctly Configuration Exposes the different configuration options for the application Please note that these configuration options are not persistent i e closing the application will reset all options Detailed configuration options are available in the Configuration Tab section of this document Utility Bar ome The utility bar exposes functional options and is reconfigured according to the selected tab Detailed operation instructions are included in specific tab subsections of this document The following controls are common to all utility bar configurations 1 Application Lo
9. ication is provided as a means for the end user to consult Request Results launch Manual Requests as well emit pharmaceutical opinions if the feature is enabled This document exposes in detail the use and operation of this application InterMED Rx Viewer General Overview and Application Organization The application is presented as a single tabbed window seen below that provides most of its functionality gt aqel LI sis jeuy uel 1 uoneJnbijuo5 T Xsi Q3i93uT 1 Application Tabs Used to expose the desired type of information 2 Utility Bar The utility bar is common to all tabs and is reconfigured according to the currently active tab 3 Request data This section presents patient request and medication related data as it would have been sent by the Interfaced Patient Management Application This section is common to the IT Table Analysis and Manual Requests tabs 4 Content section According to the currently selected tab this section will present the required information Please refer to the specific tab documentation for section content information Please refer to individual section documentation in this document for detailed descriptions InterMED Rx Page 2 Application Tabs Use these tabs to expose the desired information section of the application Available tabs are 1 IT Table Exposes the Interactions Table for the curr
10. ncentrations of Adalat It would therefore be prudent to lower the dose of Adalat ARTICLES RETAINED FOR CYP3A4 AND ADALAT AND ACTOS Use of immortalized human hepatocytes to predict the magnitude of clinical drug drug interactions caused by CYP3A4 induction Promising new approaches Prediction of the metabolic interaction of nateglinide with other drugs based on in vitro studies Update on rifampin and rifabutin drug interactions ANALYSIS 44 ADALAT and WARFARIN DECIM Te hace hun cubetenbee aea maksbolinad bar cal uoneanBijuo XM Qq3t equr I sjsanbay jenuew This instance of the utility bar contains the usual buttons and a Prepare Opinion s button which can be used to generate Pharmaceutical Opinions for the loaded request In order to generate an opinion you must have selected use the checkbox at the right hand side of the analysis one or more analysis for which to formulate an opinion For details on formulating Pharmaceutical Opinions please refer to the Formulating a Pharmaceutical Opinion section of the document Please note that headers for analysis that involve new medications for the request are displayed in red Please refer to the InterMED Rx web site for instructions about using the analysis page and interpreting the analysis itself Manual Requests Section The contents section associated with the Manual Requests tab exposes the means by which a user may send a
11. rformance The default values is 500ms Language picker The application is available in English and French Use this configuration option to switch between the two available languages Please note that the application language also sets the Web Service response language Interaction analysis selection For interface requests use this pull down to specify the type of analysis that will be automatically selected for opinion formulation You may specify that all none or only analysis involving new request meds be automatically selected Pharmacist Use this field to specify the pharmacist name that will be used to formulate a Pharmaceutical Opinion Password Used to specify the application unlock password If not specified this password defaults to intermed The password is reset to default each time the application is started Display only P450 products Use this checkbox to configure the Interactions Table If this control is checked only P 450 meds are displayed in the table Don t display checkmark Use this checkbox to configure the Interactions Table If this control is checked the isoenzyme checkmarks are replaced with text identifying the med as a substrate inhibitor or inducer This option is especially useful if you need to print the interactions table on a monochrome printer InterMED Rx Viewer Utility Windows Application Lock The application can be locked by clicking the Lock button from the utility
12. scribed below InterMED Rx Viewer Interactions Table Section The contents section associated with the IT Table tab exposes the reconstituted interactions table for the loaded request sishjeuy a 3 c LN E mo 2 E 1 a a XU GaWaqul uoneanDijuo This instance of the utility bar contains the usual buttons and an Order by dropdown which can be used to specify by which column the table is sorted The dropdown contains the isoenzymes by which the table can be sorted and selecting an isoenzyme from the dropdown results in the table being re displayed sorted by the specified column Please note that new medications for the request are displayed in red Please refer to the InterMED Rx web site for instructions about interpreting the interactions table InterMED Rx Page 7 Analysis Section The contents section associated with the Analysis tab exposes the analysis for the loaded request y InterMED Rx CYP1A2 1 CYP2B6 0 CYP2C8 0 CYP2C9 0 CYP2C19 0 CYP2D6 0 CYP3A4 3 ANALYSIS 43 ADALAT and ACTOS P450 E RESULT These two substrates are metabolized by the same cytochrome P450 isoenzyme namely CYP3A4 OPINION Moreover their respective affinities for these isoenzymes are similar However due to higher administered dose of Actos it is very likely that the latter vill suffer less interaction but vill cause a significant raise in co
13. substrate to access retained articles B Toggle entire table to brand name m Charcoal cooking C Cigarette smoking E Mebendazole uogesnbyuog 3 RS Please note that a valid account is needed to use the web site to its full potential Registration to the web site is free Configuration Section Utility The Configuration tab allows the user to configure the application according to his her preferences p It InterMED Rx Client Interface BAX m l Switch to French gt B a a Automatic selection of new interactions v Pharmacist Password sqsanbay jenuew Display only P450 products Don t display checkmark XMH Q3li193u amp j mc The available configuration options are 1 Stop Automatic Updates The InterMED Viewer application is designed to automatically display the last request made from the workstation whether it be a manual request or an interface request Use this option button to enable or disable this behavior Update Interval ms Sets the automatic update interval for the application By default the value for this parameter is 500 milliseconds This configuration parameter controls the update frequency interval for the application when automatic updates are enabled Setting this value to low may negatively impact system pe
14. ton Use the Cancel button if you wish to cancel the current opinion formulation and go to the next one Use the Cancel All button if you wish to cancel all the opinion formulations and go to the main application window If only one analysis was chosen for opinion formulation then the effect of the Cancel and Cancel All button is identical If you have chosen to preview the opinion instead of emitting printing it the Opinion Preview window will appear as shown below 2009 04 05 10 06 26 AM Dr MD 1 siu e qeL LT Doctor lo CYP3A4 3 I would like to porter votre attention certains renseignements qui concernent pat 3 3 M pavara analyzed the Mi di pat aE constate les COL eu aa concerne Arialat etc Lime Warfarin j RC C nee eee ree peus Uu Up teraction but lent to lower the r Since Warfarin demonstrates a greater affinity for CYP3A4 we should expect greater concentrations of Adalat It would therefore be prudent to lower the dosage of Adalat Given the situation pour rem dier au probl me de pat 3 My recommandation is to stop le Adalat 25 Note Comment space vitro studies T hane this infarmatinn vane cernant titilas et ma vane naurrez les inindre an dossier de nat vj pr M drug interactions uoneanBijuo I XM QI3tequr I sjsenba jenuew E C meTITITTOER
15. well as buttons to re initialize insert update and delete meds from the request The manual request med grid is for display purposes only Use the Medication Dose and unit fields together with the Reset Add Update and Delete fields to interact with the med grid To insert a med in the grid select the desired med from the pull down enter a dose and select the unit and then click the Add button To update a med in the grid select it in the med grid and adjust the dose or unit as needed then click Update Use the Delete button to delete a med from the grid after having selected it Use the Reset button to delete all the meds from the med grid Please note that it is not currently possible to formulate Pharmaceutical Opinions for manual requests InterMED Rx Section Utility The InterMED Rx tab shown below presents a simple embedded web browser which allows the user to access the InterMED Rx web site without leaving the application window This tab accesses the InterMED Rx P 450 Table by default Inter MED Rx Client Interface HOME PAGE ABOUT SITE PLAN CON T TE D CONDITIONS Tw CONTACT US aL InterMED Rx Harmony and Optimal Therapy in the use of Medication REGISTRATION P 450 Table A sqsanbay jenuew sis Ajeuy e qe LI P 450 Table Click on the pill to the left of the substrate to toggle name E Toggle entire table to generic name Click on the

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