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UAB Chemical Safety and Waste Management Manual

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1. 4 7 3 3 Segregate the chemicals according to the above classifications If there is a potential for hazardous interactions within a specific class then further separation is warranted Label the area for each class of chemical 4 7 3 4 General Rules for Compatibility 4 7 3 4 1 4 7 3 4 2 4 7 3 4 3 Highly toxic or carcinogenic chemicals should be ordered and stored in the smallest practical amount Flammable or combustible liquids must be stored in approved containers flammable material storage cabinets or in properly designed under hood storage areas No more than 10 gallons of flammable liquids may be stored outside of an approved flammable material storage cabinet No more than a total of 60 gallons of flammable liquids may be stored in a lab Please refer to the UAB General Safety Manual for more detail Water reactive chemicals should be located in a cool dry area away from potential sources of water 21 22 4 8 4 7 3 4 4 Corrosives should be separated into acid and base subclasses Large containers of corrosives should be stored on the lowest shelf or in special cabinets Acids and bases should be separated from active metals and substances that can generate toxic gases upon contact Nitric acid must be stored separately 4 7 3 4 5 Oxidizers must be separated from reducing agents and combustible or flammable chemicals 4 7 4 5 Compressed gas cylinders must be stored in well ventilated areas whe
2. Taken from Prudent Practices for Handling Hazardous Chemicals in the Laboratory 161 Appendix H Chemical Inventory Chemical Name Manufacturer Form Liquid solid Date Rec d 163 Appendix I Audit Forms Laboratory Monitoring Form Page 1 of 3 Date I D Number Investigator Building and Room s Inspected Department Contact Person Ext Campus Address Email Address Auditor 1 Are microbial agents used in this lab Agent Room Used Room Stored 2 Is DNA RNA used in this lab What Host Vector system 3 Is human blood body fluids or unfixed tissue used in this lab 4 Are animals used or housed in this lab Are animals housed in the animal facility List species 5 Are the following agents administered to animals Identify RDNA material human products infectious agents drugs exclude analgesics sedatives anesthetics etc chemicals 6 Is tissue cell culture used in this lab Primary human animal Continuous human animal source 7 What animal biosafety level of containment is used in this lab 8 What biosafety level of containment is used in this lab 9 List 5 chemicals used in the laboratory which you feel are the most hazardous include flammables hazardous drugs and extremely hazardous substances and the maximum quantity stored and the frequency of use Name Frequency Amoun
3. on O u Building s Date Room N umber s covered by this plan Date of Review Update at least annually l Standard O perating Procedures This laboratory follows general procedures set forth in the UA B Chemical Safety and Waste M anagement M anual concerning the use and handling of hazardous chemicals Below are listed any additional standard operating procedures or references used in the covered laboratories 171 Appendix Chemical Hygiene Plan Outline Additional References I Criteria for Exposure Control M easures This laboratory follows the recommendations outlined in Sections 3 and 4 of the UAB Chemical Safety and Waste M anagement M anual for the control of exposure to hazardous chemicals Materials designated as Extremely H azardous are summarized in Section 3 2 Use of any hazardous material Refer to Sections 3 and 4UAB Chenical Safety and Waste Management M anual Use of Extremely Hazardous Refer to Section 3 2 UA B Chemical Substances Safety and Waste Management M anual Fume Hoods and Protective Equipment Chemical fume hoods are certified through the Division of Biological Safety A sticker is attached to the unit at the time of certification Records of certification are kept in the office of the Department of Occupational Health and Safety Room 445 Community Health Services Building 933 19th Street South Birmingham AL 35294 Eye washes are tested weekly by laboratory personnel Safety
4. 10TX 170X 19NH 170X 10TX 19NH 170X 19NH 170X 10TX 11TX 14WS 03CA 170X 170X 10TX 10TX 10TX 10TX LITX 14WS 10TX 14WS 11TX 11TX 03CA 10TX 14WS 10TX 10TX 10TX 10TX 10TX 14WS 14WS 03CA 11TX 14WS 02CB 170X 170X 10TX 170X 19NH 19NH 10TX 11TX Appendix D UAB Waste Registry CHEMICAL NAME Sodium meta periodate Sodium metasilicate Sodium methohexital Sodium methoxide Sodium methylate Sodium methoxide Sodium molybdate Sodium molybdate dihydrate Sodium monoxide solid Sodium nitrate Sodium nitrilotriacetic acid Sodium nitrite Sodium nitroferricyanide Sodium nitroprusside Sodium nitroferricyanide Ill Sodium oleate Sodium oxalate Sodium pentabarbitol Sodium pentachlorophenoate Sodium perborate Sodium perchlorate Sodium periodate Sodium permanganate monohydrate Sodium peroxide Sodium peroxymonosulfate Sodium persulfate Sodium phenobarbitol Sodium phenolsulphonate Sodium phosphate dibasic anhydrous Sodium phosphate dibasic heptahydrate Sodium phosphate monobasic monohydrate Sodium phosphate tribasic dodecahydrate Sodium picramate wetted Sodium picrate Sodium polymetaphosphate Sodium potassium tartrate Sodium propionate Sodium p toluenesulfonate Sodium pyrophosphate Sodium pyrosulfate Sodium rhodizonate Rhodizonic acid disodium salt Sodium ricinoleate Sodium salicylate Sodium secobarbitol Sodium selenide Sodium selenite Sodium sesquicarbonate S
5. Phenoldisulfonic acid Phenolphthalein powder Phenolsulfonephthalein PSP Phenolsulfonic acid Phenolsulfonic acid p sodium salt Phenothiazine Phenoxyacetic add Explosion hazard Highly reactive May form unstable peroxides on standing CPC CODE 09FS 08FL 08FL 08FL 08FL 08FL 08FL 14WS O8FL 08FL 08FL 08FL 08FL 08FL 19NH 1555 170X 1555 10TX 170X 08FL 10TX 10TX 08FL 08FL 10TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX 08FL 10TX 08FL 10TX 10TX 03CA 10TX 10TX 10TX 10TX 03CA 10TX 10TX 10TX 129 Appendix D UAB Waste Registry CHEMICAL NAME Phenyl acetyl chloride Phenyl benzoate Phenyl beta napthylamine Phenyl biphenyl oxadiazole Phenyl carbonate Diphenyl carbonate Phenyl cellosolve 2 Phenoxyethanol Phenyl dihydrogen phosphate disodium salt Phenyl disodium phosphate Phenyl ether Phenyl fluoride Phenyl isocyanate Phenyl isothiocyanate Phenyl salicylate Phenyl sulfoxide Phenyl 1 2 propandione 2 oxime 1 Phenyl 1 2 propanedione 1 Phenyl 1 3 butanedione 1 1 Benzoylacetone Phenyl 1 propanol 3 Phenyl 2 thiourea 1 Phenyl 3 4 pyridyl propane 1 Phenyl 3 buten 2 one trans 4 Phenylacetaldehyde Phenylacetic acid Phenylacetone Phenylacetonitrile Phenylalanine Phenylanthralic acid N Phenylarsine carbazide Phenylarsine oxide Phenylazoaniline p Phenylbiguanide hydrochloride Phenylcinnamic acid alpha Phenyldiethanolamine N Phenylene diisothiocy
6. 03CA 10TX 08FL 10TX 10TX 08FL 08FL 08FL 10TX 08FL 10TX 10TX 10TX 10TX 10TX 08FL 10TX 10TX 10TX 08FL 08FL 08FL 08FL 08FL 08FL 08FL 08FL 10TX 19NH LITX 11TX 11TX 08FL 03CA 10TX 10TX 19NH 10TX 08FL 10TX 11TX 10TX 10TX Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Mucosol 10TX Muramic acid 03CA Murexide 10TX Myristic acid 10TX Myristoyl chloride 14WS N 1 naphthyl ethylenediamine dihydrochloride 10TX N 1 pyrenyl iodoactamide 10TX N 2 bromoethyl phthalimide 10TX N 3 pyrene maleimide 10TX N p hydroxyphenyl glycine 10TX N bromo succinimide 10TX N N dimethyl 1 naphthylamine 10TX N N p phenylenedimaleimide 10TX N 1 N aphthyl ethylenediamine dihydrochloride 10TX N 1 pyrene iodoacetamide 10TX N 4 dimethylamino 3 S dintrophenyl 10TX N 6 ethenoadenosine 1 10TX N 6 ethenoadenosine 5 diphosphate 1 10TX N acetyl I cysteine 10TX N acetyl tyrosinamide 10TX N acetyl D galactosamine 19N H N acetylimidazole 10TX N acetyl I tryptophanamide 10TX Nadic methyl anhydride NMA 10TX Naphtha Benzin O8FL Naphthaldehyde 1 10TX Naphthalene 10TX Naphthalene 6 sulfonic acid 10TX Naphthalenediol 1 3 10TX Naphthalenesulfonic acid 1 03CA Naphthalenesulfonyl chloride 1 14WS Naphthalenesulfonyl chloride 2 03CA Naphthoflavone 19NH Naphthoic acid 1 03CA Naphthol 10TX Naphthol acetate 10TX Naphthol AS phosphate 10TX Naphthol benzoate 10TX Naphthol bisulfa
7. 10 Are conventional refrigerators labeled as unsuitable for storage of flammable matarinla 11 When flammable materials are stored in a refrigerator is it a spark proof refrigerator 12 Are chemicals free of signs of physical or chemical change i e crystals ALINA NHA HAIN 13 Is the laboratory free of chemical damage to the facility or equipment 14 Are corrosive liquids stored below eye level 15 Are work areas for carcinogens or agents of high or unknown toxicity posted with a sign denoting a high hazard area 16 Are quantities of flammable liquids over 10 gallons stored in flammable storage cabinets 17 Is the fume hood restricted from being used for storage of chemicals 18 Are waste containers used for high risk chemicals i e yellow barrels for carcinogen contaminated material etc 19 Is secondary containment present for chemicals stored in large volumes i e 5 gal Waste collection containers etc 1 Is medical waste separated from non medical waste at the point of generation 2 Is medical waste secured and transferred to covered red plastic barrels for transport to the Hazardous Materials Facility 3 Is animal waste disposed according to UAB Medical Waste Management Plan 4 a Is liquid biological waste decontaminated by an autoclave or chemical disinfection before disposal b Is solid biological waste decontaminated by an autoclave or ch
8. 10TX H ydroxyethyl piperazine 10TX H ydroxyindole 3 acetic acid 5 10TX Hydroxyl ammonium sulfate 03CA Hydroxylamine 14WS Hydroxylami ne hydrochloride 03CA Hydroxylamine sulfate 03CA Hydroxylbenzoic acid p 03CA Hydroxymercuric benzoate p 11TX H ydroxy methoxy benzaldehyde 10TX Hydroxymethyl mercury 11TX H ydroxy naphthaldehyde 2 10TX H ydroxynaphthalimide sodium salt 10TX Hydroxynaphthol blue disodium salt 10TX Hydroxyphenyl propionate 10TX Hydroxyphenyl sulfide 10TX Hydroxyproline 19NH Hydroxypropyl methacrylate 2 10TX H ydroxyquinoline 10TX H ydroxyquinoline hemisulfate hemihydrate 8 10TX Hydroxystearic acid 12 10TX Hydroxytriaminopyrimidine sulfate 10TX Hydroxytryptamine creatinine sulfate 10TX Hydroxytyramine hydrobromide 3 10TX Hydroxytyramine 3 hydrochloride 10TX Hypaque 10TX 110 Explosion hazard Highly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE H ypophosphorous acid 03CA Hypoxanthine 10TX Ichthammol 10TX Imidazole 02CB Iminodiacetic acid 10TX Iminodiethanol 2 2 O8FL Iminothiolane 2 10TX Indalone 10TX Indantrione 1 2 3 10TX Indene 10TX Indeno 1 2 3 cd pyrene 10TX Indigo 10TX Indigo carmine 10TX Indium 09FS Indole 10TX Indole butyric acid 3 10TX Indole propionic acid 3 10TX Indole 3 acetic acid 10TX Indoleglyoxylic acid 3 10TX Indoline 08FL Indolylacetonitrile 3 10TX Inosine 10TX Inosin
9. 5 day per week time weighted average 27 28 6 3 designed to protect most healthy workers from adverse health effects Carbon Monoxide 25 ppm ACGIH Desflurane 50 ppm Manufacturer Enflurane 75 ppm ACGIH Ethylene Oxide 1 ppm OSHA Formaldehyde 0 75 ppm OSHA Glutaraldehyde 0 2 ppm OSHA H alothane 50 ppm ACGIH Isoflurane 2 ppm NIOSH Lead 50 ug m3 OSHA Mercury 0 025 mg m3 ACGIH Nitrous Oxide 50 ppm ACGIH Toluene 50 ppm ACGIH Total Dust 10 mg m3 ACGIH Xylene 100 ppm ACGIH NIOSH recommends a 2 ppm limit for all halogenated anesthetics Assessment of exposure to other chemical and physical agents can be requested through the Chemical Safety Division These agents include solvents dust silica lead carbon monoxide nitrogen dioxide explosive gases oxygen noise total illumination and non ionizing electromagnetic radiation Exposure to ionizing radiation is measured by the Radiation Safety Division Indoor Air Quality Problems Modern office buildings are generally considered safe and healthful working environments However energy conservation measures instituted during the early 1970s have minimized the infiltration of outside air and contributed to the buildup of indoor air contaminants Complaints are often of a subjective nonspecific nature and are associated with periods of occupancy These symptoms often disappear when the employee leaves the workplace They include headache dizziness nausea tiredness lac
10. Benzoylbenzoic acid all isomers Benzoyl DL alanine Benzyl acetate Benzyl acetoacetate Benzyl alcohol Benzyl benzoate Benzyl bromide Benzyl chloride Benzyl chloroformate Benzyl cyanide Benzyl dimethylamine BDMA Benzyl disulfide Benzyl ether Benzyl formate Benzyl mercaptan Benzyl salicylate Benzyladenine 6 Benzylamine Phenylmethyl amine Benzylchloromethyl ether Benzyldimethylamine Benzylethylaniline N N Benzylhydroxylamine hydrochloride o Benzylideneacetone 7A Explosion hazard Highly reactive May form unstable peroxides on standing CPC CODE 10TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX 03CA 11TX 10TX 10TX 10TX 10TX 08FL 10TX 10TX 10TX 10TX 08FL 19NH 14WS 15SS 10TX 19NH 10TX 08FL 10TX 08FL 03CA 03CA 03CA 08FL 02CB 10TX 10TX 10TX 08FL 10TX 10TX 02CB 10TX 02CB 08FL 10TX 08FL Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Benzylisothiocyanate 10TX Benzyl methylamine O8FL Benzylthiocyanate 10TX Benzylthiuronium chloride 10TX Berberine hydrochloride hydrate 10TX Beryllium 11TX Beryllium carbonate 11TX Beryllium chloride 11TX Beryllium fluoride 10TX Beryllium nitrate hydrate 170X Beryllium sulfate tetrahydrate 11TX Betaine 10TX Betaine H Cl 10TX BHT 10TX Biacetyl O8FL Bial s reagent contains HCI orcinol ferric chloride oricinol ferric 10TX chloride 5 methylresinol Bibenzyl 10TX Bicine N N dihydroxyethyl glycine 02CB Biebrich sc
11. Bradykinin triacetate 10TX Brassylic acid 10TX BRIJ 35 10TX Brilliant blueg 10TX Brilliant blue r acid blue 83 03CA Brilliant cresyl blue 10TX Brilliant green 10TX Bromcresol green 10TX Brominal 10TX Bromine 03CA Bromo 2 6 dimethyl phenol 4 10TX Bromo 2 naphthyl D galactopyranoside 6 10TX Bromo 2 naphthyl D glucuronide 6 10TX Bromo 3 methyl butane 1 O8FL Bromo 3 phenylpropane 1 O8FL Bromo 4 nitrobenzene 1 10TX Bromoacetaldehyde dimethylacetal O8FL Bromoacetamide N NBA 10TX Bromoacetanilide 4 10TX Bromoacetanilide p 10TX Bromoacetic acid 03CA Bromoacetone 08FL Bromoacetophenone 2 10TX Bromoacetophenone alpha 10TX Bromoacetyl chloride 14WS Bromoadenine 8 10TX 76 Explosion hazard H ighly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Bromoadenosine triphosphate 8 10TX Bromoadenosine 8 10TX Bromoadenosine 3 5 cyclic monophosphate 8 10TX Bromoaniline all isomers O8FL Bromobenzene O8FL Bromobenzene sulfonhydrazide 15SS Bromobenzene sulfonyl chloride p 14WS Bromobenzoic acid all isomers 10TX Bromobenzothiazole 5 10TX Bromobenzyl bromide p 03CA Bromobutane 1 08FL Bromobutane 2 08FL Bromocamphor N sulfonic acid ammonium salt D alpha 10TX Bromochlorobenzene all isomers 08FL Bromochloropropane trimethylene chlorobromide 10TX Bromocresol purple 10TX Bromocydohexane 3 Cydohexyl bromide 08FL Bromocyd open
12. Butanetriol Butanoic acid Butanol 1 butyl alcohol Butanone 2 Butaphene dinitro sec butyl phenol Butene 2 methyl 2 Butoben Butopyronoxyl Butoxyethanol 2 Butoxypolypropylene glycol Butyl acetate Butyl acrylate Butyl alcohol Butyl benzoate Buty butyrate Butyl carbamate Butyl cellosolve Butyl chloride Buty ether Butyl ethyl ether Buty formate Butyl hydroperoxide tert 78 Explosion hazard H ighly reactive May form unstable peroxides on standing CPC CODE 10TX 08FL 10TX 08FL 03CA 10TX 10TX 10TX 10TX 10TX 10TX 08FL 10TX 08FL 08FL 10TX 08FL 07CG 07CG 02CB 08FL 10TX 08FL 10TX 08FL 10TX 03CA 08FL 08FL 10TX 08FL 10TX 10TX 08FL 10TX 08FL 08FL 08FL 10TX 08FL 10TX 08FL 08FL 08FL 08FL 08FL 1555 Appendix D UAB Waste Registry CHEMICAL NAME Butyl isocyanate Butyl lithium Buty methacrylate Butyl methyl ether tert Butyl PBD Butyl peracetate t Butyl perbenzoate t Butyl peroxide t Butyl peroxybenzoate tert Butyl phenol Buty phthalate N Butyl sulfone Buty sulfoxide dibutyl sulfoxide Butyl 4 6 dinitrophenol 2 sec Butylamine Butylamine N Butylaniline p N p methoxybenzylidene Butylated hydroxyanisole Butylated hydroxytoluene Butylbenzene tert Butylcyclohexanone 4 t Butyldiethanolamine N N Butyldimethylsilyl chloride tert tert butylchlorodimethysilane Butyldisulfide Butyl hydroxytoluene bht Bu
13. Erythromycin 10TX Erythromycin stearate 10TX Erythrosin B 10TX Eserine sulfate 10TX Estradiol 10TX Ethacrynic acid 03CA Ethanedisulfonic acid 1 2 03CA Ethanedithiol 1 2 08FL Ethanesulfonic acid 03CA Ethanethiol O8FL Ethanol O8FL Ethanolamine O8FL Ethendadenosine 5 triphosphate 10TX Ether ethyl ether O8FL Ethidium bromide 10TX Ethionine DL 10TX Ethoxybenzoic acid o 03CA Ethoxyethanol 2 08FL Ethoxyethoxy ethanol 2 2 O8FL Ethoxyethyl ether 2 O8FL Ethoxyethyl benzene O8FL Ethoxylated thioether O8FL Ethyl 4 4 dichlorobenzilate 10TX Ethyl 4 nitrocinnamate 10TX Ethyl acetate O8FL Ethyl acetoacetate O8FL Ethyl acrylate O8FL Ethyl alcohol O8FL Ethyl anisate O8FL Ethyl benzoate O8FL Ethyl benzoylacetate 10TX Ethyl bromide O8FL Ethyl bromobutyrate O8FL Ethyl butyrate O8FL Ethyl carbamate 10TX Explosion hazard 101 H ighly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME Ethyl carbamate urethane Ethyl chloride Ethyl chloroacetate Ethyl chloroformate Ethyl cinnamate Ethyl cyanoacetate Ethyl diazoacetate Ethyl eosin Ethyl ether Ethyl fluoroacetate Ethyl formate Ethyl hexylamine Ethyl iodide Ethyl isocyanate Ethyl isothiocyanate ethyl thiocarbimide Ethyl lactate Ethyl laurate Ethyl magnesium bromide Ethyl maleimide N Ethyl malonate Ethyl m aminobenzoate Ethyl methacrylate inhibited Ethyl naphthylamine Ethyl oleate Ethyl oxa
14. Gluconic acid sodium salt 19NH Glucono delta lactone 10TX Gluconolactone 10TX Glucosamine hydrochloride D H 19NH Glucose D 19NH Glucuronic acid 10TX Glucuronolactone D 10TX Glutamic acid L 19N H Glutamine acid L 10TX Glutaraldehyde 10TX Glutaric acid 19N H Glutaric anhydride 10TX Glutaronitrile 10TX Glutathione 10TX Glutidine 2 10TX Glycerine O8FL Glycerol O8FL Glyceryl diacetate O8FL Glyceryl monoacetate O8FL Glyceryl monostearate 10TX Glyceryl triacetate O8FL Glycidylaldehyde O8FL Glycine 19N H Glycine ethyl ester hydrochloride 10TX Glycine methyl ester hydrochloride 10TX Glycogen 19N H Glycol methacrylate 10TX 106 Explosion hazard H ighly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Glycolic acid 10TX Glycolic acid calcium salt 10TX Glycylglycine 19N H Glycyl I histidyl l lysine acetate 19N H Glyoxal 03CA Glyoxal 40 in water 03CA Glyoxal bis 2 hydroxyanil 10TX Glyoxal bis o hydroxyanil 10TX Glyphosate N phosphonomethyl glycine 10TX Gold 11TX Gold chloride 11TX Gram s iodine solution 11TX Guaiacol O8FL Guanidine carbonate 10TX Guanidine hydrochloride 10TX Guanidine nitrate 15SS Guanidine thiocyanate 10TX Guanidineacetic acid 03CA Guanosine 5 diphosphate 19N H Guanylyl cytosine 19N H Gum arabic 19N H Gum ghatti 19N H Guthion 10TX Hanker Y ates reagent 10TX Hematoxylin 10TX Hematoxylin stain aluminum sulfate acet
15. N Nitrosodimethylaniline p Nitrosodi N butylamine Nitrosodi N propylamine Nitroso N ethylurea N Nitroso N methyl urea N N itroso N methylurethane N Nitroso N methylvinylamine N Nitrosopiperidine N Nitroso R salt Nitrostilbene 2 Nitrostyrene beta Nitrosylsulfuric acid Nitrotoluene all isomers Nitrous oxide N lauroylsarcosine NMA Nadic methyl anhydride N methylbis 2 chloroethyl amine hydrochloride N methyl N nitro N nitroso guanidine 126 Explosion hazard Highly reactive May form unstable peroxides on standing CPC CODE 10TX 1555 08FL 10TX 07CG 07CG 1555 08FL 10TX 10TX 1555 10TX 10TX 10TX 10TX 10TX 14WS 14WS 10TX 10TX 08FL 1555 03CA 1555 10TX 10TX 10TX 10TX 08FL 11TX 10TX 08FL 10TX 10TX 10TX 08FL 10TX 10TX 10TX 10TX 03CA 10TX 07CG 10TX 10TX 10TX 09FS Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE N methyl piperidine O8FL Nonane O8FL Nonanone 5 O8FL Nonenylsuccinic anhydride 10TX Nonylamine N O8FL Norborene endo 2 3 dicarboxylic anhydride acid cis 5 10TX Norborene 2 methanol 5 10TX Norbornylene 08FL Nordihydroxyguaiaretic acid 10TX N tosyl phenylalanine chloro methyl ketone 10TX N tris hydroxymethyl methyl 2 amino ethanesulfonic acid 03CA Nuclear fast red 10TX Nucleoside phosphorylase 19N H Octachlorodibenzo p dioxin 10TX Octadecane 10TX Octadecanol 1 10TX Octadecene 1 O8FL Octadecylamine 02CB O
16. Propionic acid 03CA Propionic anhydride 03CA Propionitrile 08FL Propiophenone 08FL Propyl dipropylthiocarbamate S 10TX Propyl gallate N 10TX Propyl isocyanate N 14WS Propyl methacrylate O8FL Propylamine O8FL Propylene carbonate 10TX Propylene dichloride O8FL Propylene glycol O8FL Propylene glycol monostearate 10TX Propylene oxide O8FL Propylene phenoxetol O8FL Propylmethacrylate 3 trimethoxysilyl 10TX Propyl p hydroxybenzoate 10TX Prosil Organosilane 14WS Prostaglandin El 10TX Prostaglandin F2 alpha 10TX Protease 19N H Protein kinase 19N H Protein kinase 35 cyclic AMP 19N H Pro texx mounting medium O8FL Protoporphyrin IX 10TX Protoporphyrin IX dimethyl ester 10TX Explosion hazard 135 Highly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Protosol contains methanol O8FL P tosyl l arginine methylester 10TX Pulegone 10TX Pump oil O8FL Purinethiol 10TX Puromycin dihydrochloride hydrate 10TX Putrescine 02CB PVP polyvinyl pyrrolidone 10TX Pyllodium celite 10TX Pyracin 4 pyridoxil acid beta 10TX Pyralin 15SS Pyrazinamide 2 3 Pyrazinecarboxamide 10TX Pyrazine dicarboxylic acid 2 3 10TX Pyrazole 10TX Pyrene O8FL Pyrenemethyl iodoacetate 10TX Pyrethrin synthetic 10TX Pyridine O8FL Pyridine hydrochloride 10TX Pyridine 3 aldehyde 10TX Pyridinecarboxaldehyde 2 O8FL Pyridinedicarboxylic acid 2 5 03CA Pyridinedicarboxylic ac
17. a material or mixture of materials which has a flash point see above of less than 140 F is considered flammable c Irritant A non corrosive material that causes a local reversible injury to a biological membrane at the site of contact e g chlorinated hydrocarbons lachrymators 55 Appendix A Glossary d Oxidizer A material that yields oxygen readily to stimulate the combustion of organic matter The elemental halogens are also included in this class of compounds e Poison A material that presents a health hazard through short term or chronic exposure either orally or through inhalation or skin absorption f Reactive A substance that reacts violently with water or air to produce toxic gases or explosive mixtures substances that are unstable or explosive Laboratory Scale Work with chemicals that can easily and safely be manipulated by one person excluding the commercial production of chemicals for sale Laboratory Use A workplace where relatively small quantities of hazardous chemicals are used on a non production basis Licensed Hazardous Waste Disposal Site A facility that is specifically designed and engineered to dispose of or store hazardous chemical wastes Manifest A form used for identifying and shipping hazardous materials The manifest accompanies hazardous chemical waste from the point of generation to final disposal The generator is responsible for completing the manifest properly Material
18. 1 10TX Trichloro 5 nitrobenzene 1 2 4 10TX Trichloroacetaldehyde 10TX Trichloroacetic acid 03CA Trichloroacetic acid 03CA Trichloroacetic acid sodium salt 10TX Trichloroacetonitrile 02CB Trichlorobenzene 1 2 4 10TX Trichlorobenzene 1 3 5 10TX Trichloroethane 1 1 1 10TX Trichloroethane 1 1 2 10TX Trichloroethylene 10TX Trichlorofluoromethane Fluorotrichloromethane 10TX Trichloromethane 10TX Trichloromethanesulfonic anhydride 10TX 148 Explosion hazard H ighly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Trichloromethylthio tetrahydrophthalimide N 10TX Trichlorophenol 10TX Trichlorophenol 2 4 6 sodium salt 10TX Trichlorophenoxy propionic acid 2 2 4 5 03CA Trichlorophenoxyacetic acid 2 4 5 03CA Trichlorophenoxyacetic acid butyl ester 03CA Trichlorotrifluoroethane 1 1 1 O8FL Trichlorotrifluoroethane 1 1 2 O8FL Trichrome stain 10TX Tricresyl phosphate Tritoyl phosphate 10TX Triethanolamine O8FL Triethoxysilane 14WS Triethyl orthoformate O8FL Triethyl phosphate 10TX Triethyl phosphite 14wWS Triethylamine O8FL Triethylborane 14WS Triethylene glycol O8FL Triethylene glycol dimethyl ether O8FL Triethylenetetraamine 02CB Triethylethylenediamine N N N O8FL Triethylorthoformate 14WS Triethylsilanol sodium salt 10TX Trifluoro 1 2 thienyl 1 3 butanedione 4 4 4 10TX Trifluoroacetic acid 03CA Trifluoroacetic acid sodium salt 10TX Tri
19. 10TX Nitroaniline m 10TX Nitroaniline p 10TX Nitroanisole o 10TX Nitroanisole p 10TX Nitrobarbituric acid trihydrate 5 03CA Nitrobenzaldehyde all isomers 10TX Nitrobenzene 10TX Nitrobenzeneazo alpha naphthol p 10TX Nitrobenzenesulfonyl chloride m 03CA Nitrobenzenesulfonyl chloride p 14ws Nitrobenzoic acid all isomers 03 CA Nitrobenzoic hydrazide m 10TX Nitrobenzoic acid 3 10TX Nitrobenzoyl chloride p 03CA Nitrobenzyl alcohol p 10TX Nitrobenzyl pyridine 4 p 10TX Nitrobiphenyl 4 10TX Nitrocatechol sulfate dipotassium salt hydrate p 10TX Explosion hazard 125 H ighly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME Nitrocatechol 4 Nitrocellulose pyroxylin Nitroethane Nitrofluorene 2 Nitrogen Nitrogen dioxide Nitroglycerine Nitromethane Nitrophenol Nitrophenyl acetate p Nitrophenyl hydrazine p Nitrophenyl phosphate disodium salt hexahydrate Nitrophenyl sulfate p Nitrophenyl trifluoroacetate p Nitrophenylazo 1 naphthol 4 p Nitrophenylazoresorcinol m 4 Nitrophenylphosphordichloridate p Nitrophenylsulfenyl chloride m Nitrophthalic acid 3 Nitrophthalic anhydride 3 Nitropropane 1 Nitropropane 2 Nitrosalicylic acid 5 Nitroso guanidine Nitroso 2 naphthol 1 Nitroso 2 naphthol 3 6 disulfonic acid disodium salt Nitrosodiethanolamine N Nitrosodiethylamine N Nitrosodimethylamine
20. 14WS Stannous sulfide 11TX Starch 19N H Steapsin 19N H Stearic acid 03CA Stearmide Octadecanamide 10TX Steel 11TX Steric acid 10TX Stilbene oxide cis 08FL Stilbene oxide trans 10TX Stoddard solvent 08FL Streptozotocin 10TX Strontium 14WS Strontium acetate 10TX Strontium bromide 11TX 142 Explosion hazard Highly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Strontium carbonate 11TX Strontium chloride 11TX Strontium chloride hexahydrate 11TX Strontium nitrate 170X Strontium oxide 11TX Strontium peroxide 15SS Strontium salicylate 11TX Strontium sulfate 11TX Strontium sulfide 11TX Strontium titanate 11TX Strychnine nitrate 10TX Strychnine sulfate 10TX Strychnine L 10TX Styphnic acid 15SS Styrene O8FL Styrene oxide 15SS Succinamide 10TX Succinic acid 10TX Succinic anhydride 03CA Succinimide 10TX Succinyl chloride 14WS Succinyl sulfathiazole 10TX Sudan black B 10TX Sudan III 10TX Sudan IV 10TX Sulfadiazine 10TX Sulfaguanidine 10TX Sulfamic acid 03CA Sulfamide 10TX Sulfanilamide 10TX Sulfanilic acid 03CA Sulfanilic acid sodium salt hydrate 10TX Sulfapyridine 10TX Sulfathiazole 10TX Sulfinylaniline N 08FL Sulfolane 08FL Sulfonethyl methane 10TX Sulfonic acid sodium salt 3 03CA Sulfosalicylic acid 03CA Sulfur 11TX Sulfur dichloride 14WS Sulfur hexafluoride 07CG Sulfur iodide 11TX Sulfur monochloride 14WS Sulfur trioxide pyridine 14WS Sulf
21. 2 2 3 recommendation s to the President of UAB or his designee for final action Department Chairpersons Directors Major duties or activities include the following 2 2 1 2 2 2 2 2 3 2 2 4 2 2 6 The chief administrator of each Department Research Institute or Center is responsible for the general safety of faculty staff and students working with chemicals in his her overall area of jurisdiction It should be enphasized that this responsibility is reduced in no way by activities of the Institutional Biosafety Committee Radiation Safety Committee and safety directors The chief administrator shall ensure that each principal investigator in his her area or jurisdiction is provided with access to the UAB Chemical Safety and Waste Management Manual and should stress the importance of compliance with the guidelines therein The chief administrator and the principal investigator are mutually responsible for informing Chemical Safety of work involving hazardous chemicals and reporting accidents or incidents involving chemicals to the Chemical Safety Director The department chairpersons and faculty members who supervise teaching laboratories are mutually responsible for informing students of proper precautions to be taken when working with hazardous chemicals The department chairperson and the principal investigators or supervisors are mutually responsible for ensuring that employees under their direct supervisi
22. 4 7 15SS Trinitrobenzene 1 3 5 wetted 15SS Trinitrobenzenesulfonic acid 2 4 6 15SS Trinitrobenzoic acid 2 4 6 09FS Trinitroguanidine 09FS Trinitrophenyladenosine 5 diphosphate 2 3 10TX Trinitrophenyladenosine 5 triphosphate 2 3 10TX Trioxsalen 4 5 8 Trimethylpsoralen 10TX Trioxymethylene 10TX Tripalmitin 10TX Triparanol O8FL Triphenyl methyl mercaptan 10TX Triphenyl phosphite 14WS Triphenyl 2H tetrazolium chloride 2 3 5 10TX Triphenylcarbinol Triphenylmethanol 10TX Triphenylchloromethane 10TX Triphenylimidazole 2 4 5 Lophine 10TX Triphenylmethane 10TX Triphenylmethyl bromide 10TX Triphenyl phosphine 10TX Triphenyl phosphine oxide 10TX Tris 10TX Tris 2 3 dibromopropyl phosphate 10TX Tris dimethylaminomethyl phenol 2 4 6 10TX Tris hydroxymethyl aminomethane 10TX Tris hydroxymethyl methyl 2 amino 1 ethanesulfonic add 2 TES 10TX Tris barbital sodium barbital 10TX Trisodium phosphate 02CB Trisodium N hydroxy ethylenediaminetriacetate 10TX Trithiane 1 3 5 10TX Triton B N Benzyltrimethylammonium hydroxide 10TX Triton X 100 10TX 150 Explosion hazard Highly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Triton X 400 10TX Triton X 405 contains lithium carbonate 10TX Trizma base 10TX Trizma maleate 10TX Tromethamine Tris hydroxymethyl aminomethane 10TX Tropinone O8FL Trypan blue dye 10TX Trypsin 19N H Tryps
23. 6 08FL Hexanediol 2 5 10TX Hexanedione 2 5 08FL Hexanenitrile 08FL Hexanss mixture of isomers 08FL Hexanilide 10TX Hexanoic acid 03CA Hexanol 1 08FL Hexazinone triazine pesticide 10TX Hexene 1 08FL H exene 2 one 5 O8FL H exestrol 10TX Hexokinase 19NH Hexonediamine 1 6 10TX Hexyl alcohol O8FL Hexyl methyl ketone O8FL Hexyl sulfide 10TX Hexylamine N O8FL Hexylene glycol 10TX H exylresorcinol 10TX 108 Explosion hazard H ighly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME Hippuric acid Hippuric acid sodium salt Histamine Histamine dihydrochloride Histamine diphosphate Histidine monohydrochloride Histidine L Histopaque Homocysteine Hyamine H yamine 1622 Hydrazine dihydrochloride Hydrazine hydrate Hydrazine monohydrochloride Hydrazine sulfate Hydrazine anhydrous Hydrazinobenzene sulfonic acid p Hydrindantin Hydriodic acid Hydrobenzene sulfonamide N Hydrobenzoic acid m Hydrobromic acid Hydrochloric acid Hydrocinnamaldehyde Hydrocinnamic acid Hydrocortisone Hydrocyanic acid liquified Hydrofluasilicic acid Hydrofluoric acid solution Hydrogen gas Hydrogen fluoride pyridine Hydrogen peroxide 3 Hydrogen peroxide solution Hydrogen sulfide gas Hydrogen tetrachloroaurate Hydroquinone Hydroquinone 2 5 bis 1 1 dimethylpropyl Hydroxide of hyamine Hydroxy naphthol blue H ydroxy 1 2 hydrox
24. Chromium trioxide 170X Chromotrope 2R 11TX Chromotropic acid 1 8 dihydroxynaphthalene 3 6 sulfonic acid 10TX Chromotropic acid sodium salt 10TX Chrysene 10TX Chymotrypsin 19NH Cibacron blue 10TX Cinchonine 10TX Cineole 08FL Cinnamaldehyde trans 08FL Cinnamamide 10TX Cinnamic acid trans 10TX Cinnamoyl chloride 14WS Citraconic acid 03CA Citraconic anhydride 03CA Citric acid 19NH Citronellal O8FL Citrondlol 1 O8FL Citrulline DL 19N H Citrus red 10TX Clayton yellow 10TX CM cellulose 19N H CM sephadex 10TX CN Br activated sepharose 11TX Coal tar distillates O8FL Cobalt 11TX Cobalt II acetate anhydrous 11TX Cobalt II acetate tetrahydrate 11TX Cobalt II carbonate 11TX Cobalt I1 chloride anhydrous 11TX Cobalt II chloride hexahydrate 11TX Cobalt II fluoride 11TX Explosion hazard 85 Highly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Cobalt II nitrate hexahydrate 170X Cobalt II oxide 11TX Cobalt II sulfate hexahydrate 11TX Cobalt III acetate anhydrous 170X Cobalt III fluoride anhydrous 170X Cobalt chromate 170X Cobalt naphthenate 11TX Cobalt nitrate 170X Cobalt trifluoride 170X Cobalt Il sulfate hydrate 11TX Cobaltic oxide 11TX Cochineal 10TX Coconut oil O8FL Colcemid 10TX Colchicine 10TX Collidine 2 4 6 2 4 6 trimethyl pyridine O8FL Collodion O8FL Concanavalin a 10TX Congo red 10TX Congo red stain 10TX Coomassie blue 1
25. DL valine 19N H DMA 08FL DMAE p acetamidobenzoate 10TX DMP 30 2 4 6 tris dimethylamino methyl phenol 10TX DMSO dimethylsulfoxide O8FL Docosane 10TX Dodecane O8FL Dodecanedioic acid 03CA Dodecanethiol 1 O8FL Dodecanol 1 10TX Dodecene 1 sodium dodecylbenzene sulfonate O8FL Dodecenyl succinic anhydride DDSA 10TX Dodecyl aldehyde O8FL Dodecylamine 02CB Dopa L 19N H Dopamine 10TX Dowex 19N H Dowex ion retardation resin 19N H Doxorubicin 10TX Drabkin s solution contains cyanide 10TX Dricote contains methylene chloride 10TX Dulcitol galactitol 19N H Dursban chlorpyrifos 10TX Dyphylline 10TX Eastman universal indicator 10TX EDAC ethylaluminium dichloride 14ws EDTA 10TX EGTA 10TX Elastase 19N H Elenious acid H 25e03 170X Ellagic acid 03CA Elon 10TX Embedding media 08FL Emetine 10TX Endrin 10TX Enflurane 10TX Enhance 08FL Eosin B 10TX Eosin Y 10TX Ephedrine 10TX Ephedrine alkaloid 10TX Ephedrine sulfate 10TX Epibromohydrin O8FL Epichlorohydrin O8FL 100 Explosion hazard H ighly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Epichlorohydrin triethanolamine cdlulose EC TEOLA cellulose 10TX Epinephrine 10TX Epon 812 epoxide 10TX Epon resin 10TX Epoxy resin 10TX Epoxy activated sepharose 10TX Epoxypropoxy phenylpropane 2 2 bis p 2 3 10TX Erepsin 19NH Ergosterol 10TX Eriochrome black T 10TX Erucic acid 10TX Erythorbic acid 03CA
26. Dimethyl acetophenone 2 4 O8FL Dimethyl acetylenedicarboxylate 10TX Dimethyl azobenzene 10TX Dimethyl benzophenone 10TX Dimethyl carbonate 14WS Dimethyl dichlorosilane O8FL Dimethyl disulfide O8FL Dimethyl dodecylamine N oxide N N 10TX Explosion hazard 95 Highly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Dimethyl fumarate 10TX Dimethyl malonate O8FL Dimethyl nitroaniline 10TX Dimethyl phenethyl alcohol 10TX Dimethyl phenol all isomers 03CA Dimethyl phosphite O8FL Dimethyl phthalate 10TX Dimethyl piperidine 2 6 O8FL Dimethyl POPOP 10TX Dimethyl pyrazine 2 5 O8FL Dimethyl sulfate 14WS Dimethyl sulfoxide 10TX Dimethyl terephthalate 10TX Dimethyl tetrachloroterephthalate 10TX Dimethyl tin oxide 10TX Dimethyl urea 1 3 10TX Dimethyl yellow 10TX Dimethyl 1 3 propanediamine 1 2 O8FL Dimethyl 1 3 cyclohexanedione 5 5 10TX Dimethyl 1 3 propanediol 2 2 10TX Dimethyl 1 4 cyclohexanedicarboxylate 10TX Dimethyl 1 naphthylamine N N 10TX Dimethyl 1 phenylpyrrole 2 5 10TX Dimethyl 2 butanone 3 3 O8FL Dimethyl 2 nitrobenzene 1 3 nitroxylene 10TX Dimethyl 3 nitrobenzene 1 2 10TX Dimethyl 3 pentanol 2 2 O8FL Dimethyl 4 heptanone 2 6 O8FL Dimethylacetamide N N O8FL Dimethylallylamine O8FL Dimethylamine DMA inhibited O8FL Dimethylamine salt of 2 4 D 10TX Dimethylamino 1 propanol 3 O8FL Dimethylamino 2 3 benzophenoxazine 8
27. Mercaptomethanol Mercaptopropionic acid 3 Mercaptopyridine 2 Mercaptosuccinic acid Mercuric II nitrate Mercuric acetate Mercuric bromide Mercuric chloride Mercuric cyanide Mercuric dichromate Mercuric iodide Mercuric nitrate Mercuric oleate Mercuric oxide Mercuric oxide red Mercuric oxide yellow Mercuric oxycyanide Mercuric potassium iodide Mercuric salicylate Mercuric succinimide Mercuric sulfate Mercuric sulfide Mercuric thiocyanate Mercurochrome Mercurous chloride mercury chloride Mercurous nitrate Mercurous oxide Mercurous sulfate solid Mercury I iodide Mercury II iodide Mercury contaminated labware Mercury fulminate Mercury tamer clean up kit contains mercuric sulfate Mercury metallic Merthiolate Mesityl oxide Mesitylene Metaldehyde Metanil yellow Metaphosphoric acid phosphoric acid meta Met a terge Methacholine chloride Methacrylic acid Explosion hazard H ighly reactive May form unstable peroxides on standing CPC CODE 10TX 10TX 08FL 10TX 08FL 03CA 08FL 03CA 11TX 11TX 1ITX 11TX 11TX 170X 1ITX 170X 11TX 11TX 11TX 11TX 11TX 11TX 11TX 1ITX 11TX 11TX 11TX 11TX 1ITX 170X 11TX 11TX 11TX 11TX 1ITX 1555 11TX 11TX 11TX O8FL 08FL 10TX 10TX 03CA 10TX 10TX 03CA 117 Appendix D UAB Waste Registry CHEMICAL NAME Methacrylonitrile Methacryloyl chloride Methallyl chloride M ethane gas M ethanesulfonic acid M
28. Mitotane Mitoxantrone H Cl Nafarelin Acetate Pentamidine Pipobroman Placlitaxel Plicamycin Procarbazine HCI Ribavirin Streptozocin 188 Estraderm topical Estrace vaginal Emcyt Estinyl VePesid FUDR Proscar Adrucil Eulexin Cytovene H ydrea Idamycin Ifex Recombinant DNA 2a Roferon A 2b Intron Human Leukocyte n3 Alferon N Accutane Lupron Depot Lupron Depot Ped Ergamisol CeeN U Mustargen Nitrogen M ustard Depo Provera Provera Amen Curretab Cycrin M egace Alkeran Purinethol M ethotrexate Na M exate Rheumatrex Mutamycin Lysodren N ovantrone Synarel Pentam Vercyte Taxol Mithracin Matulane Virazole Zanosar Appendix M Safe Handling of Hazardous Drugs Tamoxifen Citrate Testolactone Thioguanine Thiotepa Uracil Mustard Vidarabine Vinblastine Sulfate Vincristine Zidovudine Nolvadex Tamoxifen Citrate Teslac Thioguanine Tabloid Thiotepa Parenteral Uracil Mustard caps Vira A Vinblastine Sulfate Velban Oncovin Vincasar PFS Retrovir ALL INVESTIGATIONAL DRUGS SHOULD BE CONSIDERED HAZARDOUS UNLESS THEIR EXCLUSION CAN BE SUPPORTED BY SCIENTIFIC EVIDENCE This list is to be updated as needed by the Pharmacy and Therapeutics Committee 189
29. Personnel wear gloves goggles lab coats and other appropriate personal protective equipment when handling hazardous materials CSWMM Sec 3 1 BSM 4 2 and GHSMP p 53 There is no eating or drinking in areas where chemicals are used or stored CSWMM Sec 3 1 5 and BSM 4 2 1 Safety showers and eyewashes are clearly marked and easily accessible Eyewashes are checked regularly See the eyewash checklist available on the Department of Occupational Health and Safety website CSWMM Sec 3 1 13 and 3 1 9 BSM 4 2 9 Hazardous materials are stored by hazard class No acids and bases or oxidizers and flammables stored together CSWMM Sec 4 7 3 Corrosive liquids are stored below eye level Chemicals that can form explosive peroxides ethers tetrahydrofuran are dated when received dated when opened and discarded by the expiration date CSWMM App B All chemicals are labeled correctly and legibly Includes secondary containers CSWMM Sec 4 5 Outdated chemicals very old chemicals and expired reagents are disposed of properly through the HMF Try to discard or recycle chemicals which have not been used for over a year CSWMM Sec 11 Regular refrigerators are labeled Not for Flammable Storage GHSMP p 39 No flammables are stored in regular refrigerators GHSMP p 41 Large amounts of flammables up to the legal limit for a given size lab are stored in flammable storage cabinets GHSMP p 40 41 Sharps containers ar
30. Rhoplex 10TX Riboflavin 19N H Ribonuclease A 19N H Rifampin 10TX Rivanol 10TX Rotenone O8FL Roundup 10TX Rubeanic acid Dithiooxamide 10TX Rubeanic acid in ethanol O8FL Rubidium chloride 11TX Rubidium nitrate 170X Ruthenium 09FS Ruthenium IV oxide 11TX Saccharin 19NH Safranine O 10TX Safranine stain 10TX Safrole 08FL Explosion hazard 137 Highly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME Salbutamol Salicylaldehyde Salicylaldoxime Salicylamide o acetic acid Salicylanilide Salicylhydroxamic acid Salicylic acid Salicylic acid 5 p nitrophenylazo sodium salt Alizarin yellow CG Salicyloyl hydrazide Santo white Saponin Sarital Sodium thiamylal Savasol Schiff s reagent Scintigest Tissue solubilizer Sclex 30 WP Sebacic acid Sebacoyl chloride Seleninyl chloride Selenium oxychloride Selenium Selenium dioxide Selenium disulfide Selenourea Semicarbazide hydrochloride Sencor Sephadex G10 Sephadex G200 Sephadex G50 Serine DL Serotonin creatinine sulfate monohydrate Sevin Sevinol 4 Sigma 104 phosphatase substrate tablets Silane Silcane Silica gel Silicic acid Silicon Silicon carbide Silicon dioxide Silicone Silicone A 172 Silicone rubber Silicotungstic acid hydrate Silver Silver acetate Silver benzoate 138 Explosion hazard H ighly reactive May form unstable peroxides on standing CPC CODE 10T
31. Tetanus The University of Alabama at Birmingham 445 Community Health Services Building 19 933 19 Street South Birmingham Alabama 35294 1041 205 934 2487 FAX 205 934 7487 Appendix Chemical Hygiene Plan Outline Chemical H ygiene Plan The UAB Department of Occupational Health and Safety requires each laboratory on campus to develop and abide by a written Chemical Hygiene Plan CHP as outlined by the U S Occupational Safety and H ealth Administration OSHA in 29 CFR 1910 1450 Occupational Exposure to H azardous Chemicals in Laboratories The following document is designed to serve as a guide for Principal Investigators Laboratory Directors Managers and Supervisors to fulfill this requirement The CHP must protect employees from health hazards associated with chemicals used in that laboratory and keep exposures to hazardous chemicals below the levels set forth in 29 CFR 1910 subpart Z The required elements of the plan are Standard O perating Procedures Criteria for Exposure Control M easures Fume Hoods and Protective Equipment Information and Training Circumstances Requiring Prior Approval Medical Consultation and Examination Chemical Hygiene Officer Work with Extremely H azardous Substances Principal Investigator Laboratory Chemical H ygiene Officer Manager Director or Supervisor Department Campus Address PB WN B
32. and placed in the wastebasket 114 Yellow Barrel and Chemotherapy Waste Certain toxins carcinogens or chemicals causing reproductive hazards are not regulated by EPA but do pose significant hazard to the environment or those working with them These must be disposed of by incineration Since most of the medical waste is microwaved waste requiring incineration is placed in ydlow barrels rather than the traditional red medical waste barrel Examples of carcinogens reproductive toxins or hazardous drugs include but are not limited to Mitomycin Cyclophosphamide BRDU DMBA Streptozotocin Ethidium bromide Select agent toxins MNU Chemicals of unknown toxicity Consult with Chemical Safety 42487 for disposal of other carcinogens select agent toxins reproductive toxins or hazardous drugs 11 4 1 Hospital Areas All items potentially contaminated with chemotherapy agents must be disposed of in approved containers Chemogators obtained from Hospital Materials Management Containers should be placed in each room where chemotherapy is administered Used IV bags tubing needles gowns and waste generated during a spill clean up involving chemotherapy agents are placed in the containers These containers are picked up with medical waste 11 4 2 Non Hospital Areas Items that are or contain mutagens carcinogens teratogens or chemotherapy agents should be placed in yellow barrels for incineration This includes chemic
33. are adequate Eating Smoking etc Do not eat drink smoke chew gum or apply cosmetics in laboratory areas where chemicals are present Do not consume food or drinks with glassware or utensils that are used for laboratory procedures N ever store food material in refrigerators or storage areas containing chemicals Always wash hands before and after any activity involving the use of chemicals Exiting the Lab All exits should be clear of obstruction Wash exposed skin before leaving the laboratory Mouth Suction Do not use mouth suction for pipetting or starting a siphon Personal Apparel Confine long hair and loose clothing Long pants are preferred when working with hazardous materials Shorts and short skirts are not recommended If these are worn a lab coat closed front gown or apron should be worn for spill protection Wear shoes at all times in the laboratory however sandals open toe or perforated shoes are not adequate 10 3 19 Personal Housekeeping Keep the work area clean and unduttered with chemicals and equipment being properly labeled and stored Inspect eye wash stations weekly and safety showers annually 3 1 10 Planning Seek information and advice about hazards plan appropriate protective procedures and positioning of equipment before beginning any new operation 3 1 11 Unattended Operations Leave lights on place an appropriate sign on the door and provide a method for containment of toxic substa
34. beverages restricted from the space where laboratory work is being performed 9 Are safety showers and eyewashes UAB approved tested easily accessible marked 10 Are fume hoods functioning properly and certified according to UAB policy 11 Are housekeeping practices good with no excessive clutter present 12 Are laboratory doors kept closed while experiments are in progress and in accordance with general safety and fire guidelines 13 Are emergency phone numbers and after hours contacts posted on exterior laboratory doors and near telephones 1 Is a current chemical inventory maintained in the lab 2 Do lab personnel have access to MSDS information 3 Is waste disposal documented and records maintained in the laboratory for two years 4 Are hazardous chemicals properly segregated by hazard class see Chemical Management Section 5 of Chemical Safety and Waste Management 5 Are chemical storage areas properly posted with signage indicating hazard classes i e acids flammables 6 Are containers of ether and other peroxide forming chemicals dated 7 Are chemicals properly and legibly labeled See Section 5 of Chemical Safety and Waste Management 11 99 Appendix I Audit Forms Laboratory Monitoring Form Page 3 of 3 8 Are chemicals within the manufacturer s expiration date 9 Are chemical containers undamaged and in good condition
35. bromide Cuprous chloride Cuprous cyanide Cuprous iodide Cuprous oxide Cyanamide calcium salt Cyanazine Cyanide Cyanoacetamide 2 Cyanoacetic acid Cyanobenzalehyde p Cyanogen Cyanogen bromide Explosion hazard H ighly reactive May form unstable peroxides on standing CPC CODE 10TX 10TX 08FL 03CA 10TX 08FL 10TX 08FL 1555 08FL 10TX 08FL 11TX 11TX 11TX 11TX 11TX 1ITX 1ITX 1ITX 11TX 1ITX 1ITX 170X 170X 10TX 11TX 11TX 11TX 1ITX 11TX 10TX 10TX 11TX 11TX 1ITX 11TX 11TX 11TX 10TX 10TX 10TX 03CA 10TX 07CG 11TX 87 Appendix D UAB Waste Registry CHEMICAL NAME Cyanogen chloride Cyanogum catalyst Cyanopyridine Cyanopyridine 4 Cyanopyridine N oxide 4 Cyanopyrimidine 3 Cyanuric acid Cyanuric chloride Cyclaine hexylcaine HCl Cycloheptanone Cyclohexaamylose Cyclohexamide Cyclohexane Cyclohexanecarboxylic acid Cyclohexanedicarboxylic anhydride Cyclohexanedione 5 5 dimethyl 1 3 Cyclohexanidione 1 4 Cyclohexanol Cyclohexanone Cyclohexene Cyclohexene oxide Cycloheximide Cydohexyl 3 2 morpholinoethyl carbodiimide metho p toluenesulfonate Cydohexyl 3 2 morpholinoethyl carbodiimide methyl p toluene Cyclohexy1 3 thiourea 1 Cyclohexylamine Cyclohexylenedinitrilotetraacetic acid 1 2 Cyclohexylpiperidine N Cyclooctane Cyclopentadiene 1 3 Cyclopentane Cyclopentanol Cyclopentanone Cyclopentenone 2 Cycloph
36. ethanesulfonic acid ethyl ester Methanesulfonyl chloride M ethanol Methapyrilene M ethenamine Methiodal sodium Methionine Methionine sulfone M ethomyl M ethone 5 5 dimethylcyd ohexane 1 3 di one Methotrexate M ethoxy 1 butanol 3 M ethoxy 2 nitroaniline 4 M ethoxy 5 nitroaniline 2 M ethoxyacetic acid M ethoxyacetophenone M ethoxybenzaldehyde o anisaldehyde o M ethoxybenzaldehyde 4 anisaldehyde p M ethoxybenzenethiol M ethoxybenzoic acid all isomers M ethoxy beta naphthylamine 4 M ethoxycydohexanol 2 M ethoxycydohexanol 4 Methoxyethanol 2 M ethoxyethyl acetate 2 M ethoxyethyl ether M ethoxyethyl phthalate beta Methoxyethylamine M ethoxyethylether bis M ethoxyphenol all isomers Methyindole 1 Methyl acetate Methyl acetoacetate Methyl acrylamide Methyl acrylate Methyl alcohol Methyl aniline Methyl aniline N Methyl anisate Methyl anisole o Methyl azoxy methanol Methyl benzoate 118 Explosion hazard Highly reactive May form unstable peroxides on standing CPC CODE O8FL 14WS 08FL 07CG 03CA 10TX 14WS OSFL 10TX O9FS 10TX 19N H 10TX 10TX 10TX 10TX 08FL 10TX 10TX 03CA 10TX 10TX 10TX 10TX 10TX 10TX 08FL 08FL 08FL 08FL 08FL 10TX 08FL 08FL 10TX 08FL 08FL 08FL 10TX 08FL 08FL 08FL 08FL 08FL 08FL 08FL 08FL Appendix D UAB Waste Registry CHEMICAL NAME Methyl bromide Methyl bromide liquid Methyl bromoacetate Me
37. exhaust ventilation and no air recirculation 6 3 2 Recommended Temperature and Humidity The American Society of Heating Refrigerating and Air Conditioning Engineers ASHRAE suggests indoor temperature and humidity ranges as listed in the table below These values assume building occupants will be wearing light indoor clothing Relative H umidity Winter T emperature Summer T emperature 68 5 F 76 0 F 74 0 F 80 0 F 68 5 F 75 5 F 73 5 F 79 5 F 29 68 5 F 74 5 F 73 0 F 79 0 F 60 68 0 F 74 0 F 72 5 F 78 0 F Indoor relative humidity should be kept below 60 to discourage mold growth Temperatures above 76 F have been assodated with indoor air quality complaints regardless of the relative humidity 6 3 3 Sample Collection Initial sampling will normally consist of collecting environmental data for temperature humidity and airborne contaminants that may include formaldehyde carbon dioxide carbon monoxide nitrogen dioxide ozone and total hydrocarbons 6 3 3 1 Airborne Contaminant Levels Carbon dioxide measurement is a useful screening technique that is often helpful in determining whether adequate quantities of outside fresh air have been introduced and distributed into the building The following list relates various levels of carbon dioxide with expected air quality perception These levels are only guidelines If carbon dioxide levels exceed 1000 ppm it does not indicate that th
38. monitoring reveals that exposure to an OSHA regulated substance with monitoring and medical surveillance requirements routinely exceeds the action level or Permissible Exposure Limit PEL e A spill leak or explosion has occurred in the laboratory which could have resulted in a hazardous exposure Non emergency consultation will be provided through The Workplace Emergency treatment will be provided through the University H ospital Emergency Department List other provisions for medical consultations and examinations below M edical Provider 174 Appendix Chemical Hygiene Plan Outline VII Chemical Hygiene Officer List the name campus address and extension of the individual designated as Chemical Hygiene Officer for this laboratory on page one of this document According to 29 CFR 1910 1450 Chemical Hygiene O fficer means an employee who is designated by the employer and who is qualified by training or experience to provide technical guidance in the development and implementation of the provisions of the Chemical H ygiene Plan This definition is not intended to place limitations on the position description or job classification that the designated individual shall hold within the employer s organizational structure VIII Work with Extremely Hazardous Substances Below is an inventory of those agents designated by the University as Extremely H azardous Substances and any additional control measures specific to this labo
39. o cyclohexyl phenol 4 6 Dinitrophenol 2 4 Dinitrophenylazo 1 naphthol 3 6 disulfonic acid 2 2 4 disodium salt Dinitrophenylhydrazine 2 4 Dinitro p toluic acid 3 5 Dinitrosalicylic acid 3 5 Dinitrose naphthalenediol Dinitrotoluene 2 4 Dinitrotoluene 2 6 Di N octylamine Dinonylphthalate Dinoseb methacrylate Dioctyl phthalate Dioctyl sebacate Dioctyl sodium sulfosuccinate Dioctylphthalate bis 2 ethylhexyl phthalate Dioctylphthalate oil Di o isopropylidene mannitol 1 2 5 6 Diothane HCI Dioxane 1 4 Dipentene Dipentylamine Diphenic acid Diphenyl chlorophosphate Diphenyl diselenide Diphenyl methane 4 4 diisocyanate Diphenyl phenanthroline Diphenyl phosphite Diphenyl 1 10 phenanthroline 4 7 Diphenyl 1 3 5 hexatriene 1 6 Diphenyl 2 propanone 1 3 Diphenylacetamide N N 98 Explosion hazard H ighly reactive May form unstable peroxides on standing CPC CODE O8FL 10TX 10TX 08FL 10TX 10TX 10TX 1555 10TX 1555 1555 1555 14WS 10TX 1555 10TX 1555 10TX 09FS 10TX 1555 10TX 1555 1555 10TX 08FL 10TX 10TX 10TX 10TX 08FL 10TX 10TX 10TX 08FL 08FL 08FL 10TX 14ws 11TX 14WS 10TX 14WS 10TX 10TX 10TX 10TX Appendix D UAB Waste Registry CHEMICAL NAME Diphenylacetic acid Diphenylacetonitrile Diphenylamine Diphenylamine 4 sulfonic acid sodium salt Diphenylbenzidine N N Diphenylboric acid Diphenylbutadiyne Diphenylcarbamyl chlorid
40. or a Drug Enforcement Agency DEA registration number before ordering Chemical Inventory The chemical hygiene officer must create an inventory of every hazardous substance known to be present in the workplace This hazardous chemical inventory must be updated regularly Material Safety Data Sheets MSDS must be available electronically or in hard copy form for review by employees 4 3 1 Accessibility Any employee can review or copy this written Chemical Safety and Waste Management Manual the chemical inventory their Chemical Hygiene Plan or the MSDS files by contacting their chemical hygiene officer or the Chemical Safety Director in the Department of Occupational Health and Safety 4 3 2 Hazard Determination The manufacturer must supply an MSDS to the chemical hygiene officer if a chemical or chemical product is hazardous 4 3 3 Hazardous substances include Any substance listed in 29 CFR 1910 subpart Z http www osha sic gov O shStd toc OSHA Std toc 1910 SUBPART _Z html Any substance listed in The American Conference of Governmental Industrial Hygienists Threshold Limit Values for Chemical Substances and Physical Agents inthe Workplace The National Toxicology Programs NTP Annual Report on Carcinogens International Agency for Research on Cancers IARC Monographs Any substance otherwise known to be hazardous Manufacturers as a minimum must survey MSDSs for all substances on these lists Ma
41. or treated patients investigational drugs OSHA Hazardous D rugs Altretamine Aminoglutethimide Azathioprine L A sparaginase Bleomycin Busulfan Carboplatin Carmustine Chlorambucil Chloramphenicol Chlorotrianisene Chlorozotocin Cyclosporin Cisplatin Cyclophosphamide Cytarabine Dacarbazine Dactinomycin Daunorubicin Diethylstilbesterol Doxorubicin Estradiol Estramustine Ethinyl Estradiol Etoposide Floxuridine Finasteride Fluorouracil Flutamide Gancyclovir H ydroxyurea Idarubicin Ifosfamide Interferon Alfa Isotretinoin Leuprolide Levamisole Lomustine M echlorethamine M edroxyprogesterone M egestrol M elphalan M ercaptopurine M ethotrexate Mitomycin Mitotane Mitoxantrone Nafarelin Pentamidine Pipobroman Paditaxel Plicamycin Procarbazine Ribavirin Streptozotocin Tamoxifen Testolactone Thioguanine Thiotepa Uracil M ustard Vidarabine Vinblastine Vinaristine Ziduvidine All investigational drugs should be considered hazardous unless their exclusion can be supported by scientific evidence 15 16 3 4 3 Persons administering these drugs or using them in research should refer to the precautions in Appendix M 4 CHEMICAL MANAGEMENT 4 1 4 2 Chemical Hygiene Plan 4 1 1 4 1 2 4 1 3 The UAB Department of Occupational Health and Safety requires each laboratory on campus to develop and abide by a written Chemical Hygiene Plan CHP as outlined by the U S Occupational Safety an
42. the containers Boxes with bulging tops will not be picked up 11 5 1 3 5 Boxes should be taped closed before pick up with the exception of those containing picric acid These must be left open so that facility personnel can verify that the material is wet enough for safe transport 11 5 2 Step Two Completing the Manifest The label for the chemical waste is called a packing manifest Hazardous chemical and universal wastes require manifests for disposal A manifest must be completed and attached to each box These may be obtained from OH amp S or the OH amp S website Laboratory personnel need to complete the manifest by following the directions below and using the information provided in the Appendices 11 2 1 Laboratory Information Fill in the generator name i e principal investigator lab director telephone number department building room number and the date 11 5 2 2 Waste Information 51 52 Each container must have its contents identified on the manifest Non specified chemical waste items are extremely difficult for hazardous material personne to handle Good laboratory record keeping and labeling of all chemicals and chemical wastes prevents unknown waste items If you have a non specified waste item call the Hazardous Materials Manager for assistance 4 3797 Any chemical material that is potentially recyclable should not be contaminated with other chemicals for disposal Where appropriate note on
43. 0TX Copper 11TX Copper II nitrate 170X Copper chromite catalyst 11TX Copper napthenate 11TX Copper plating solution 11TX Copper sulfate pentahydrate 11TX Corn oil vegetable oil peanut oil O8FL Corrosion component C 02CB Cotinine O8FL Cotton blue 10TX Coumaric acid 2 03CA Coumaric acid 3 03CA Coumaric acid 4 03CA Coumarin 10TX Coumarinyl maleaimide 3 10TX Coverbond 10TX Creatine 19N H Creatine zinc chloride 10TX Creatinine 19N H Creosote O8FL Cresol 03CA Cresolsulfonaphthalein m 10TX Cresolsulfonaphthalein o 10TX Cresotinic acid p 10TX Cresyl acetate p tolyl acetate 10TX Cresyl violet acetate 10TX 86 Explosion hazard H ighly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME Cresyl violet acetate stain perchlorate Croton oil Crotonaldehyde Crotonic acid Cruachem deblock solution contains dichloromethane trichloroacetic acid Crude oil petroleum Crystal violet Cumene Cumene hydroperoxide Cumidine Cupferron Cupric 8 hydroxyquinolinolate Cupric acetate anhydrous Cupric acetate monohydrate Cupric acetoarsenite Cupric arsenate Cupric bromide Cupric carbonate Cupric chloride Cupric chloride hydrate Cupric chromite Cupric citrate Cupric cyanide Cupric nitrate Cupric nitrate hydrate Cupric oxalate Cupric oxide Cupric phosphate Cupric selenite Cupric sulfate Cupric sulfide Cupric tartrate Cuprin Cuprous
44. 0TX Titanium dioxide Titanium IV oxide 11TX Titanium metal powder wet 14WS Titanium sulfate 11TX Titanium tetrachloride Titanium IV chloride 14WS Titanium trichloride 14WS Titanous chloride 14ws Tocopherol vitamin E 19NH Tocopherol acetate DL alpha 19NH Tolidine o 10TX Toluene 08FL Explosion hazard 147 Highly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Toluene sulfonamide p 10TX Toluene 2 4 diisocyanate 14WS Toluenesulfonic acid hydrate sodium salt 10TX Toluenesulfonic acid p monohydrate 03CA Toluenesulfonyl chloride 03CA Toluenesulfonyl fluoride p 14ws Toluenethiol p thiocresol 08FL Toluhydroquinone M ethylhydroquinone 10TX Toluic acid 03CA Toluidine blue o 10TX Toluidine hydrochloride o 10TX Toluidine all isomers 08FL Tolunitrile o 08FL Toluonitrile m 10TX Toluoyl chloride o 14ws Tolyazo o toluidine 5 o 10TX Tolylmercuric chloride p 11TX Tosyl chloride Toluenesulfonyl chloride 14ws Tosylamino 2 phenylethyl chromomethy ketone 10TX Transfer RNA 19N H Transfer ribonuclein 19NH Tri 2 pyridyl 1 3 5 triazine 2 4 6 10TX Tri dimethylaminomethyl phenol 11TX Triacetin 10TX Triallyl phosphate O8FL Triaminotriphenyl methane 10TX Tribromophenol 2 4 6 10TX Tribromopropane 1 2 3 10TX Tributyl phosphate O8FL Tributyl phosphine 03CA Tributylamime OSFL Tributyltin hydride 14WS Trichloro 2 methyl 2 propanol 1 1
45. 10TX Dimethylaminoazobenzene 4 10TX Dimethylaminoazobenzene p methyl yellow 10TX Dimethylaminobenzaldehyde p 10TX Dimethylaminobenzene p sylidine O8FL Dimethylaminobenzoic acid m 10TX Dimethylaminobenzophenone 4 10TX Dimethylaminocinnamaldehyde 4 10TX Dimethylaminoethanol O8FL Dimethylaminonaphthalene 1 sulfonyl fluoride 5 10TX Dimethylaminonaphthalene 1 sulfonylaziridine 5 10TX Dimethylaminonaphthalene sulfonyl chloride 10TX Dimethylaminopropionitrile O8FL Dimethylaminopropionitrile beta O8FL 06 Explosion hazard H ighly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME Dimethylaminopropiophenone beta Dimethylaminopyridine 4 Dimethylaniline all isomers Dimethylanthracene 9 10 Dimethylbenz a anthracene 7 12 Dimethylbenz a anthracene 9 10 Dimethyl benzenesulfonic acid sodium salt Dimethylbenzenesulfonic acid 2 5 Dimethylbenzidine 3 3 Dimethylbenzimidazole 2 5 Dimethylbenzyl hydroperoxide Dimethylbenzylamine BDM A Dimethylbenzylamine HCI Dimethylbenzylamine N N Dimethylcarbamoyl chloride Dimethylcyclohexanedione Dimethylcyclohexylamine 2 3 Dimethyldichlorosilane Dimethyldithiocarbamic acid sodium salt Dimethylethanolamine N N Dimethylformamide Dimethylformamide N N Dimethylglyoxime Dimethylhydrazine Dimethylimidazole Dimethylmercury Dimethylnaphthalene 1 6 Dimethylnitrosamine Dimethyl o phenylene diamine dihydr
46. 113 Waste Reduction 11 3 1 11 3 2 Waste Minimization 11 3 1 1 Avoid purchasing and using large quantities when it is not necessary 113 1 2 Implement microscale techniques whenever possible Flammable Organic Solvents 11 3 2 1 Collection for reuse Many flammable organics can be reused for fuel unless they are extremely toxic or give off toxic products of combustion Do not combine any other chemicals with the flammable organic solvents listed below Halogenated Solvents solvents containing chlorine fluorine or bromine acutely toxic flammables acids bases heavy metals oxidizers and pesticides should be collected in separate containers The following is a list of the most frequently encountered compounds that are suitable for heat recovery Acetone Methyl alcohol 2 Butanol Methyl cellosolve Butyl alcohol Pentane Cyclohexane Petroleum ether Diethyl ether 2 Propanol Ethyl acetate Sec butyl alcohol Ethyl alcohol Tert butyl alcohol Heptane Tetrahydrofuran 45 Hexane Xylene 11 3 3 Disposal of Chemicals Down the Sink or Sanitary Sewer System Very few chemical wastes produced in laboratories are acceptable for disposal down the sink or sanitary sewer system The Jefferson County Sewer Usg Pretreatment Ordinance establishes uniform requirements for all users of the wastewater treatment system for Jefferson County Many chemicals can interfere with the proper function of the treatment facility and can render them
47. 3 Acetonitrile Acetophenetidin Acetophenol Acetophenone Acetovanillone Acetoxime Acetyl bromide Acetyl chloride Acetyl ferrocene Acetyl fluoride Acetyl pyridine 3 Acetyl 10 chlorophenarsazine 5 A cetyl 2 phenyl hydrazine 1 Acetyl 2 thiourea Acetyl alpha D glucosamine N Acetylaminofluorene 2 Acetylanthranilic acid N Acetyl beta methyl choline chloride AcetyIchlorophenarsazine N Explosion hazard Highly reactive May form unstable peroxides on standing CPC CODE 10TX 10TX 10TX 10TX 08FL 08FL O9FS 10TX 08FL 10TX 10TX 10TX 03CA 10TX 10TX 10TX 03CA 08FL 03CA 10TX 10TX 08FL 10TX 08FL 10TX 03CA 08FL 10TX 10TX 08FL 10TX 10TX 14ws 14WS 10TX 14WS 10TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX 65 Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Acetylcholine bromide 10TX Acetylcholine chloride 10TX Acetylcholine iodide 10TX Acetylcyclohexanone 2 O8FL Acetylene 07CG Acetylglycine 10TX Acetylimidazole 1 10TX Aceylneuraminic acid 10TX Acetyl penicillamine N 10TX Acetyl phenoxylacetic acid p 03CA Acetylpiperidine 1 10TX Acid phosphatase 10TX Acid potassium phthalate 10TX Acotinic acid 10TX Acridine 10TX Acridine orange 10TX Acriflavine hydrochloride 10TX Acrolein inhibited O8FL Acrylamide 10TX Acrylic acid O8FL Acrylonitrile O8FL Adenine 19N H Adenine sulfate 19N H Adenosine 19N H Adenosine triphosphate 19N H Ad
48. 5 Chlorosuccinimide N Chlorosulfonic acid Chlorotetracycline hydrochloride Chlorothymol Chlorotoluene all isomers Chlorotriethylamine hydrochloride 2 Chlorotrimethysilane Chlorotriphenyl methane Chlorpromazine hydrochloride Chlorpropamide Chlorprothixene Chlorpyriphos Cholesterol Cholesteryl acetate Cholesteryl chloride Cholesteryl oleate Cholesteryl pal mitate Cholesteryl pelargonate Cholic acid Choline chloride Chromatographic alumina basic Chromatographic alumina neutral Chrome alum Chromerge Chromic VI oxide 84 Explosion hazard Highly reactive May form unstable peroxides on standing CPC CODE 10TX 170X 11TX 10TX 03CA 10TX 10TX 10TX 10TX 19NH 08FL 11TX 10TX 10TX 08FL 08FL 03CA 10TX 14WS O8FL 10TX 10TX 170X 170X 10TX 10TX 08FL 03CA 14WS 03CA 10TX 10TX 10TX 10TX 10TX 19NH 19NH 19NH 19NH 19NH 10TX 19NH 11TX 11TX 1ITX 170X 1ITX Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Chromic acid 170X Chromic carbonate 19N H Chromic nitrate 170X Chromic oxide Chromium III oxide 11TX Chromium 11TX Chromium III chloride anhydrous 11TX Chromium III chloride hexahydrate 11TX Chromium III hydroxide 02CB Chromium III perchlorate 15SS Chromium III sulfate hydrate 11TX Chromium acetate 11TX Chromium ammonium sulfate A mmonium chromium sulfate 11TX Chromium nitrate 170X Chromium oxide 11TX Chromium potassium sulfate dodecahydrate 11TX
49. 555 1555 11TX 11TX 11TX 11TX 10TX 10TX 10TX 02CB 14WS 10TX 19NH 10TX 11TX 14WS 14WS 19NH 1ITX 11TX 19NH 1555 10TX 10TX 10TX 10TX 19NH 170X 03CA 1555 11TX 19N H 14ws LITX 1ITX 11TX 19NH 139 Appendix D UAB Waste Registry CHEMICAL NAME Sodium chloranilate Sodium chlorate Sodium chloride Sodium chlorite Sodium chloroacetate Sodium cholate Sodium chromate tetrahydrate Sodium citrate Sodium cobaltinitrite Sodium hexanitrocobaltate Sodium cyanate Sodium cyanide solid Sodium cyanoborohydride Sodium diacetate Sodium dichloro S triazinetrione Sodium dichromate dihydrate Sodium diethyl dithiocarbamate Sodium diethyldithiocarbamate trihydrate Sodium diethyldithiocarbonate Sodium dimethyldithiocarbamate Sodium dithionate Sodium dithionite Sodium dodecyl sulfate Sodium ethoxide Sodium ferric ethylenediamine tetraacetate Sodium ferrocyanide Sodium fluoride Sodium fluoroacetate Sodium fluoroborate Sodium formate Sodium glycholate Sodium glycocholate Sodium hexane sulfonate Sodium hippurate Sodium hydride Sodium hydride in mineral oil Sodium hydrogen sulfate Sodium hydrogen sulfite Sodium hydrosulfite Sodium hydroxide Sodium hypobromite Sodium hypochlorite Sodium hypophosphite Sodium iodate Sodium iodide Sodium lactate Sodium lauryl sulfate Sodium metabisulfite 140 Explosion hazard H ighly reactive May form unstable peroxides on standing CPC CODE
50. Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Methylaminophenol sulfate p 10TX Methylaminophenol p 10TX Methylaniline N O8FL Methylanthraquinone 2 10TX Methylaziridine 2 O8FL Methylbenzethonium hydroxide 10TX Methylbenzophenone 4 10TX Methylbenzoxazole 2 02CB Methylbenzyl alcohol O8FL Methylbenzylamine DL 02CB Methylbutane 2 O8FL Methylbutyric acid 2 03CA Methylcatechol 4 10TX Methylcholanthrene 10TX M ethylcyclohex 1 ene 4 O8FL M ethylcyclohexane O8FL M ethylcyclohexanol O8FL M ethylcyclohexanone O8FL Methylcydohexyl phenylurea 11TX Methyl D glucoside alpha 19N H Methyldichlorosilane 14ws Methyldiethanolamine N 10TX Methyl D mannoside alpha 19N H Methylene blue 10TX Methylene chloride 10TX Methylene disalicylic acid 5 5 03CA Methylene iodide O8FL Methylene isobutyl ketone M ethyl 2 pentanone O8FL Methylenebis 2 chloroaniline 4 4 10TX Methylenebis acrylamide N N 10TX Methylenedianiline 4 4 10TX Methylenedioxybenzene 1 2 O8FL Methylformanilide N O8FL Methylglucamine N 10TX Methylglyoxal O8FL Methylguanosine 7 10TX Methylhydrazine 15SS Methylimidazole 2 03CA Methyllactonitrile 2 OSFL Methylmorpholine 4 OSFL M ethyI N 3 methylbutyl 2 heptylamine 6 OSFL Methylnaphthalene 1 O8FL Methylnitrobenzoate m 10TX Methyl N nitro N nitrosoguanidine N 09FS M ethyl N nitroso urea N 10TX Methyl N nitrosoaniline N 10TX Methyloctadecylamine N 10TX Exp
51. CB Thallium formate 11TX Thallium nitrate 170X Thallium selenide 11TX Thallium sulfate 11TX Thallous acetate 11TX THAM Tris hydroxymethyl aminomethane 10TX Thenoyltrifluoroacetone 10TX Theobromine sodium salicylate 10TX Thiabenazole 10TX Thiamine hydrochloride 19NH Thimerosal 11TX Thioacetamide 10TX Thioacetic acid Thiolacetic acid 14ws Thioaceturide 03CA Thioanisole 08FL Thiobarbituric acid 2 10TX Thiocaprolactam 10TX 146 Explosion hazard Highly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Thiocarbanilide 10TX Thiocarbohydrazide 10TX Thiodiethanol 2 2 O8FL Thiodiglycol 2 2 Thiodiethanol 08FL Thiodipropionic acid 10TX Thioglycolic acid 03CA Thiolactic acid 03CA Thiolyte 10TX Thiomalicacid M ercaptosuccinic acid 03CA Thionin 10TX Thionyl chloride 14WS Thionylaniline N 10TX Thiophene 10TX Thiophenol 10TX Thiopyronin 10TX Thioridazine hydrochloride 10TX Thiosalicylic acid 10TX Thiosemicarbazide 10TX Thiourea 10TX Thioxane 1 4 10TX Thioxanthen 9 one 10TX Thiram Tetramethylthiuram disulfide 10TX Thixotropic gel powder 10TX Thorium nitrate 11TX Thrombin 10TX Thymidine 5 diphoshpate 19N H Thymol 10TX Thymol blue 10TX Thymolphthalein 10TX Thymolsulfonaphthalein 10TX Tiglic acid 03CA Tin 11TX Tin II chloride 11TX Tin II chloride dihydrate 11TX Tin chloride 11TX Tincture benzoin compound O8FL Titan yellow Thiazol yellow 1
52. COMPRESSED GASES CG Compressed gases and liquefied compressed gases 08 FLAMMABLE LIQUIDS FL General organic solvents not to be packed with oxidants and corrosives and oils used for heat recovery 09 FLAMMABLE SOLIDS FS 10 TOXIC ORGANICS TX Liquid irritants lachrymators etc halogenated organics non flammable solid irritants organic dyes and stains 11 TOXIC INORGANICS TX Cyanide Heavy metals 12 ORGANIC PEROXIDES OX Organic peroxides 14 WATER SENSITIVE WS 15 SHOCK SENSITIVE SS 16 OXIDIZERNA NA Nitric acid packaged by itself 17 OXIDIZER General OX General oxidizers permanganates perchlorates etc 63 Appendix C Chemical Packing Codes OXIDIZER SC SC Sulfuric and chromic acids packed only with each other NON HAZARDOUS NH Non hazardous materials Sugars amino acids etc Appendix D UAB Waste Registry CHEMICAL NAME Aatrex Abate Acenaphthene Acepromazine maleate A cetal Acetaldehyde Acetaldehyde ammonia trimer Acetaldehyde sodium bisulfite Acetaldoxime Acetamide Acetamidine hydrochloride Acetamidobenzaldehyde p Acetamidobenzoic acid p Acetamino 1 3 dimethylbenzene 4 Acetaminophen 2 H ydroxyacetanilide Acetanilide Acetic acid Acetic acid methanol 50 50 Acetic anhydride Acetoacetanilide Aceto aceto toluidide Acetol H ydroxyacetone Acetonaphthone 2 Acetone Acetone sodium bisulfite Acetonedicarboxylic acid 1
53. Chemical Safety and Waste Management Manual University of Alabama nn ingham beet artme nt of Occ cupat Bal Hes alth amp Safety Chemica Safety Division 2002 EDITION 1 INTRODUCTION usssssesrsosnenensenenensnnanensnsnnensnsnssnsnsnnsnnnsnnsnsnnnnsnsnnsnnnnsnensensnenensnnenee 3 2 RESPONSIBILITIES csssssssesesesseeseseesenesnensnssssnsnssssnsnensnsnssnensnsnssnensnsneananeneanenenes 5 2 1 CHEMICAL SAFETY DIRECTOR 00 0000002002000000200020000200220222202022200200000000000000000 5 2 2 DEPARTMENT CHAIRPERSONS DIRECTORS eren 6 23 PRINCIPAL INVESTIGATOR SUPERVISOR eer ener 6 24 HAZARDOUS AND REGULATED MATERIALS MANAGER eren 7 25 CHEMICAL HYGIENE OFFICER 0200e0000000000202020000020020010020010000212202 20220000 00000000000 8 2 6 DESIGNEE RR ERU ssrr essen 8 2 7 EMPLOYEES eesseessecssesssesssessoessesssosescosecosscosesososososoesoooosesosososessoessssccssessessseseoesose 8 3 BASIC SAFETY RULES FOR WORKING WITH CHEMICALS 9 3 1 leui TN E 9 3 2 WORK WITH CARCINOGENS REPRODUCTIVE TOXINS ACUTELY TOXIC AGENTS OR CHEMICALS OF UNKNOWN TOXICITY nennen 11 33 WORK WITH SELECT AGENT TOXINS COVERED UNDER 42 CFR 72 13 3 4 SAFE HANDLING PROCEDURES FOR ADMINISTERING HAZARDOUS DRUGS AANE AREENAN EEEIEE OSSEO ROAA ERARA AEAEE EN SAADA AS ER VERS PR AA N 14 4 CHEMICAL MANAGEMENT ussssssessessnssse
54. DATE OPENED DATE TESTED NEGATIVE POSITIVE IF TEST ISNEGATIVE PRODUCT MAY BE USED FOR 3MORE MONTHS Peroxide test strips which can be used to demonstrate the presence or absence of peroxides are available from Fisher Lab Safety Supply and other distributors of general chemical supplies If no peroxides are detected the container label should be marked to indicate the absence of peroxides and the date of the test The material can then be retained for an additional three months If peroxides are detected the Department of Occupational Health amp Safety should be notified immediately N ote Appendix B Highly Reactive Compounds The following are particularly susceptible to peroxide formation and should be retained a maximum of 6 months after receipt or three months after opening whichever occurs sooner unless stabilized in which case the six month after opening rule will apply Cyclohexene Cyclooctene Diethyl ether Isopropyl ether p Dioxane Sodium amide Tetrahydrofuran Petroleum ether is not an ether but is a mixture of hydrocarbons of the methane series The following should be retained a maximum of 12 months after receipt or 6 months after opening Acrylonitrile Butadiene Chlorotrifluoroethylene Tetrafl uoroethylene Vinyl chloride Vinyl ethers Vinylidene chloride The following materials may be subject to peroxidization They should be dated upon receipt and be kept no longer than 24 months Peroxide Ha
55. N Tetramethylbenzidine 3 3 5 5 Tetramethyldiaminomethane N N N N Tetramethyldisilane 1 1 2 2 Explosion hazard Highly reactive May form unstable peroxides on standing CPC CODE O8FL 08FL 08FL 10TX 10TX 10TX 14WS 10TX 08FL 10TX 10TX 08FL 08FL 08FL 10TX 10TX 02CB 170X 10TX 08FL 03CA 10TX 10TX 02CB 08FL 08FL 08FL 10TX 08FL 10TX 10TX 10TX 08FL 10TX 08FL 10TX 14WS 10TX 14WS 10TX 10TX 08FL 08FL 03CA 10TX 08FL 14WS 145 Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Tetramethylene sulfone 10TX Tetramethylethylenediamine N N N N Temed O8FL Tetramethylpentadecane 2 6 10 14 10TX Tetramethylphenanthroline 10TX Tetramethylpiperdine 2 2 6 6 O8FL Tetramethyl p phenylene diamine 10TX Tetramethylsilane O8FL Tetramethylsilane O8FL Tetramethylthiuram disulfide 10TX Tetramethyltin O8FL Tetramethylurea 1 1 3 3 10TX Tetranitromethane 15SS Tetra N propylammonium iodide 10TX Tetraphene 1 2 Benzanthracene 10TX Tetraphenylboron sodium Sodium tetraphenylborate 10TX Tetraphenylcyclopentadienone 10TX Tetraphenylethylene O8FL Tetrapropylammonium hydroxide 02CB Tetrasodium pyrophosphate 11TX Tetrasodium tetraacetic acid 10TX Tetrazole 10TX Tetrazolium chloride 10TX Tetrazotized o dianisidine 10TX Thallic III nitrate trihydrate 170X Thallium 11TX Thallium III oxide 11TX Thallium acetate 10TX Thallium carbonate 11TX Thallium chloride 11TX Thallium ethoxide 02
56. Na K Mg Ca Sulfates Na K Mg Ca NH4 Fluorides Ca 11 3 6 3 Laboratory M aterials Chromatographic adsorbents Filter paper without hazardous chemical residue N on contaminated glassware Rubber Gloves 11 3 7 Solvent Recycling The Department of Occupational Health and Safety currently recycles xylene and alcohol from histology laboratories and sells the solvents back to departments at a reduced rate Laboratories interested in participating in the program should contact the Hazardous Materials Facility M anager at 4 3797 11 3 8 Teaching Laboratory Samples Teaching assistants will be responsible for the collection and disposal of all student samples from their laboratory section No samples should be left in student drawers or out in the laboratory If the sample is non hazardous chenical waste and is water soluble it can be washed down the sink The vial should be handled as described below If the sample is not water soluble it can be left in the vial and placed in a separate can or plastic bag clearly labeled as non hazardous solid waste and put in the wastebasket If the student sample is hazardous chemical waste the sample vial should be emptied into an appropriately sized container obtained from the stockroom The waste should then be evaluated for in lab reduction procedures packed and labeled as described in this manual The empty vials should be placed in a plastic bag clearly labeled as non hazardous waste
57. Safety Data Sheet MSDS Safety and health information required to be supplied by the chemical manufacturer with the purchase of each new chemical or chemical product containing hazardous constituents Mutagen A substance that is capable of changing cells in such a way that future cell generations are affected M utagenic substances are usually considered suspect carcinogens Permissible Exposure Limit PEL The legally allowed concentration in the workplace that is considered a safe level of exposure for an 8 hour work shift 40 hours per week These values are established by the Occupational Safety and Health Administration OSHA in 29 CFR 1910 Select Agent a microorganism virus bacterium fungus rickettsia or toxin listed in Appendix A of 42 CFR 72 Theterm also includes 1 genetically modified microorganisms or genetic elements from organisms on Appendix A shown to produce or encode for a factor associated with a disease and 2 genetically modified microorganisms or genetic elements that contain nucleic acid sequences coding for any of the toxins on Appendix A or their toxic subunits 56 Appendix A Glossary TCLP Toxicity Characteristic Leaching Procedure The EPA test used to determine the leachability of toxic constituents into the environment Teratogen A substance that is capable of causing deformity in newborns if a significant exposure exists during pregnancy Threshold Limit Value TLV The amount of
58. TX Kodak D 76 developer 02CB Lacmoid 10TX Lactalbumin 10TX Lactate dehydrogenase 19N H Lactic acid 10TX Lactic dehydrogenase 19N H Lactonitrile O8FL Lactose alpha 19N H Lanthanum chloride anhydrous 11TX Lanthanum nitrate hexahydrate 170X Lanthanum oxide 11TX Lard 19N H Larvin LE thiodicarb 10TX Explosion hazard 113 H ighly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Lasiocarpine 10TX Lasso 10TX Lauric acid 10TX L Dopa 19NH Lead 11TX Lead acetate 11TX Lead arsenate solid 11TX Lead bromide 11TX Lead carbonate 11TX Lead chloride 11TX Lead chromate 11TX Lead citrate 11TX Lead cyanide 11TX Lead dioxide 170X Lead fluoborate 11TX Lead iodide 11TX Lead nitrate 170X Lead oxide 11TX Lead perchlorate 15SS Lead peroxide PbO2 15SS Lead phosphate 11TX Lead sesquioxide 11TX Lead subacetate 11TX Lead sulfate 11TX Lead sulfide 11TX Lead tartrate 11TX Lead tetraacetate 11TX Lead tetroxide Pb304 11TX Leucine L 19N H Leucomycin adipate 10TX Levamisole hydrochloride 10TX Levulinic acid 03CA Light green SF 10TX Ligroin 08FL Limonene dioxide 08FL Limonene D 08FL Lindane 10TX Linoleic acid 10TX Linseed oil 10TX Linuron 10TX Liquifluor 08FL Litharge 11TX Lithium 3 5 diiodosalicylate 11TX Lithium acetate 10TX Lithium acetate dihydrate 10TX Lithium Acetylide 14WS Lithium aluminum 14WS 114 Explosion hazard H ighly reactive May form unstable pero
59. X 08FL 10TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX 08FL 03CA 08FL 10TX 03CA 14WS 03CA 11TX 11TX 11TX 10TX 10TX 10TX 19N H 19N H 19N H 19N H 10TX 10TX 10TX 10TX 07CG 14WS 19NH 19NH 11TX 19NH 19NH 10TX 10TX 10TX 03CA 11TX 11TX 10TX Appendix D UAB Waste Registry CHEMICAL NAME Silver bromide Silver carbonate Silver chlorate Silver chloride Silver cyanide Silver diethyldithiocarbamate Silver iodide Silver nitrate Silver nucleinate Silver oxide Silver perchlorate anhydrous Silver picrate Silver plating solution Silver proteinate Silver stain Silver sulfate Silvex Sitosterol beta Skatole 3 M ethylindole Soda lime Sodium Sodium 2 mercaptobenzothiazole Sodium acetate Sodium alizarinesulfonate Alizarin Red S Sodium aluminate solid Sodium amalgam Sodium amide Sodium ammonium phosphate Sodium arsenate dibasic Sodium arsenite Sodium ascorbate Sodium azide Sodium barbitol Sodium benzenesulfonate Sodium benzoate Sodium beta naphthalenesulfonate Sodium bicarbonate Sodium bismuthate Sodium bisulfate Sodium bisulfide Sodium hydrosulfide hydrate Sodium bisulfite Sodium borate Sodium tetraborate Sodium borohydride Sodium bromate Sodium bromide Sodium cacodylate Sodium carbonate Explosion hazard H ighly reactive May form unstable peroxides on standing CPC CODE 11TX 11TX 170X 11TX 11TX 11TX 11TX 170X 10TX 11TX 1
60. a 3 2 for minimum design and performance requirements of emergency eyewash and shower equipment 3 1 13 2 Wall mounted eyewash units must be Speakman SE 400 or equivalent Swing away deck mounted units must be Speakman SE 572 or equivalent All units shall deliver potable water Hand held drench hoses may be used as support devices for approved eyewash and shower units but shall not replace them in any manner Eyewash stations consisting of gravity fed or hand held bottles of solution are not acceptable 3 1 13 3 Atleast one safety shower must be located within 25 feet of a laboratory entrance Such a location may be in a corridor and one shower may serve multiple laboratory units Every laboratory must have access to a safety shower unless written documentation can be provided stating the laboratory will not use any material irritating to the skin or eyes Safety showers must be Speakman SE 236 PR or equivalent and must deliver potable water Floor drains are not required 3 1 14 Working Alone Avoid working alone in a building do not work alone in a laboratory if procedures are hazardous or potentially hazardous Work With Carcinogens Reproductive Toxins Acutely Toxic Agents or Chemicals of Unknown Toxicity Additional precautions should be taken when using these compounds If you are considering pregnancy handle these substances only in a hood with a confirmed satisfactory performance using appropriate protective apparel e
61. acene 10TX Dibenzofuran 10TX Dibenzopyrene 1 2 7 8 10TX Dibenzothiophene 10TX Dibenzyl ketone 1 3 diphenyl 2 propanone 10TX Dibromo 1 2 diphenylethane meso 1 2 10TX Dibromo 1 propanol 2 3 10TX Dibromo 3 chloropropane 1 2 O8FL Dibromoacetophenone 2 4 10TX Dibromoacetophenone alpha p 03CA Dibromoaniline 2 5 10TX Dibromobenzene 08FL Dibromobutan 2 ol 1 4 O8FL Dibromobutane 10TX 90 Explosion hazard Highly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Dibromocyclohexane trans 1 2 O8FL Dibromoethane 1 2 10TX Dibromo o creosulfonephthalein 5 5 bromocresol purple 10TX Dibromopentane 1 5 10TX Dibromophosphate propanol 10TX Dibromopropane 2 3 10TX Dibromopropane 1 3 O8FL Dibromo p xylene alpha alpha 03CA Dibromoquinone 4 chloroimide 2 6 10TX Dibromothymolsulfone phthalein 3 3 bromothymol blue 10TX Dibromotoluene alpha alpha 10TX Dibutyl phosphate O8FL Dibutyl phosphite O8FL Dibutyl phthalate 10TX Dibutylamine O8FL Dibutylbutyl phosphonate O8FL Dibutyltin dichloride 14WS Dicamba 3 6 dichloro 2 methoxybenzoic acid 03CA Dicarboxylic acid anhydride O8FL Dicetyl phosphate 10TX Dichloro 2 propanol 1 3 O8FL Dichloro 2 butene cis 1 4 O8FL Dichloro 2 hydroxybenzenesulfonic acid sodium salt 3 5 14WS Dichloro 2 methylacrylanilide 3 4 10TX Dichloro 2 nitrobenzene 1 4 10TX Dichloro 3 6 dihydroxy p benzoquinone 10TX Dich
62. acid Pivaloyl chloride Platinum IV chloride Platinum IV oxide PM SF alpha Toluenesulfonyl fluoride P nitrophenyl acetic acid Podophyllum Poly dimethylsiloxane simethicone Poly ethyl acrylate Poly ethylene glycol Poly ethylene oxide Poly methyl methacrylate Poly propylene glycol Poly sebacic acid Poly vinyl alcohol Poly vinyl chloride Poly vinyl methyl ether 132 Explosion hazard H ighly reactive May form unstable peroxides on standing CPC CODE 10TX 10TX 10TX 10TX 14WS 10TX 10TX 10TX 08FL 03CA 10TX 08FL 1555 1555 10TX 1555 1555 1555 10TX 10TX 10TX 08FL 08FL 08FL 02CB 10TX 10TX 08FL 10TX 10TX 10TX 14WS 1ITX 11TX 14WS 10TX 10TX 10TX 08FL 10TX 10TX 10TX 08FL 03CA 10TX 10TX 08FL Appendix D UAB Waste Registry CHEMICAL NAME Poly vinyl pyrrolidone Polyacrylamide Polybrene H exadimethrine bromide Polybutadiene Polychlorinated biphenyls Polyethylene Polyethylene beads resin Polyethylene glycol Polygalacturonic acid Poly I Iysine Polymethyl acrylate Polymethylmethacrylate Polyoxyethylene ether Polyoxyethylene lauryl ether Polyphosphoric acid Polyram 80 WD niagara Polysolv reducer Diethylene glycol dimethyl ether Polystyrene macropourous Polyvinyl pyrrolidine Polyvinylpolypyrrolidone Ponceau S Pontacyl violet POPOP Potassium Potassium acetate Potassium aluminum sulfate dodecahydrate Potassium antimonate hydrate Potassium arsen
63. al H ealth and Safety should be contacted to determine if medical surveillance or consultation is warranted 33 8 PERSONAL PROTECTIVE EQUIPMENT 8 1 8 2 8 3 8 4 8 5 8 6 8 7 8 8 Minimize the risk of injury or exposure by using the appropriate personal protective equipment such as protective eyewear gloves and lab coats whenever chemicals are in use Consult the following information about the use of protective clothing Gloves Must be of a material compatible with the chemicals used see Appendix G Gloves should be checked for holes or tears before each use Safety Glasses Safety glasses alone should not be used when working with liquid chemicals Safety glasses are primarily for deflecting objects away from the eyes Splash goggles Form the liquid proof seal around the eyes necessary when working with liquid chemicals Goggles with face shield For chemicals that are more hazardous corrosives and hot chemicals both face shield and goggles must be used The goggles protect the eyes in case the splash is from the side or beneath the shield Laboratory coat Long sleeved coats offer the wearer some skin protection against minor splashes allowing the chemical to react with something before reacting with the skin and offering the victim time to remove the coat and shower Laboratory coat and apron Rubberized aprons offer additional time to react to the splash than the coat alone Arm guards should be
64. alcium oxide Calcium pantothenate Calcium perchlorate Calcium phenol sulfonate Calcium phosphate Calcium phosphide Calcium propionate Calcium sulfate drierite Calcium sulfate dihydrate gypsum Calcium sulfide Calcium metal Calcon sulfonic acid dye contains zinc Calcon dye calconcarboxylic acid Camphene Camphor Camphor sulfonic acid D Camphor D Camphor DL 80 Explosion hazard Highly reactive May form unstable peroxides on standing CPC CODE 11TX 1ITX 170X 11TX 11TX 11TX 1ITX 10TX 10TX 10TX 10TX 19N H 11TX 14WS 19N H 19N H 170X 11TX 11TX 170X 11TX 19N H 14WS 19NH 02CB 170X 11TX 11TX 170X 11TX 10TX 1555 10TX 19NH 14WS 10TX 19NH 19NH 02CB 14WS 10TX 03CA 10TX 10TX 09FS 10TX 10TX Appendix D UAB Waste Registry CHEMICAL NAME Camphoric acid D Camptothecin Canada balsam Canon toner petroleum solvent methacrylate copolymer carbon Caproic acid N Caprolactam Caprylic acid Carbamazepine Carbazole Carbitol Carbobenzoxy chloride Carbocaine Carbofuran Carbon disulfide Carbon monoxide gas Carbon tetrachloride tetrachloromethane Carbon trifluoride Carbon activated Carbon decolorizing Carbonyl cyanide Carbonyl fluoride Carbonyl sulfide gas Carbosorb ammonium hydroxide Carbowax Carboxymethoxylamine hemi hydrochloride Carboxyphenyl chloromercury p Carboxypropyl disulfide Carmine Carnitine hydrochloride Carot
65. als tissue and animal specimens and other non sharp contaminated materials Sharps needles blades glass should be disposed of in rigid Chemogator type containers Yellow barrels are obtained from the Hazardous Materials Facility Chemogators may be obtained from Hospital Material Management or from laboratory equipment suppliers Pick up of yellow barrel waste should be arranged with the Hazardous Materials Facility 49 50 11 5 Hazardous Waste Disposal The University of Alabama at Birmingham is required to comply with federal and state regulations regarding the packing labeling and transport of hazardous materials Before contacting the Hazardous Materials Facility for waste removal the following procedures must be completed Improperly packed or labeled waste cannot b the Waste 11 5 1 1 Containers Collect each chemical waste in a separate screw top container Do not mix waste streams Use the smallest container size to match the amount of chemical waste generated The container the chemical was originally shipped in is an ideal waste collection container if it is an appropriate size All waste containers must be tightly capped Each container must be labeled as to chemical content For mixtures give approximate percentages of each chemical compound Milk jugs are not acceptable for chemical storage If using a container that originally contained another chemical completely remove the original label prior to relabeli
66. anate 1 4 Phenylenediamine dihydrochloride p Phenylenediamine monohydrochloride Phenylenediamine all isomers Phenylenediamine N phenyl p Phenylenediaminedihydroxide p Phenylethylenediamine N Phenylglycine Phenylhydrazine Phenylhydrazine hydrochloride Phenyllithium Phenyllithium in benzene ether Phenylmercuric acetate Phenylmercuric bromide 130 Explosion hazard H ighly reactive May form unstable peroxides on standing CPC CODE 14WS 10TX 10TX 10TX 10TX 1555 10TX 10TX 10TX 08FL 14WS 14WS 10TX 10TX 10TX 08FL 10TX 08FL 10TX 10TX 08FL 08FL 03CA 08FL 08FL 19NH 03CA 10TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX 02CB 10TX 10TX 10TX 10TX 1555 1555 14WS 14WS 10TX 10TX Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Phenylmercuric chloride 10TX Phenylmercuric nitrate basic 10TX Phenylmercuritriethanol ammonium lactate 10TX Phenylmethylsulfonyl fluoride 14WS Phenylphenol sodium salt tetrahydrate o 10TX Phenyl phenol all isomers 10TX Phenylpropiolic acid 10TX Phenylsulfide 10TX Phenyltrichlorosilane 14WS Phenyltrimethylammonium iodide 10TX Phenylurea Phenyl carbamide 10TX Phenytoin 10TX Phloroglucinol dihydrate 10TX Phloxine B 10TX Phorate 10TX Phorbol 10TX Phorbol myristate acetate 10TX Phosdrin 10TX Phosgene 07CG Phosphamidon 10TX Phosphatidyl L serine 19NH Phosphine 07CG Phosphoenol pyruvate 19N H Phosphogluconic acid 6 19N H Phosphomolybdic aci
67. andling a direct or indirect exposure through blood and body fluid to a hazardous agent a Skin exposure procedure i Identify the hazardous agent ii Wash area thoroughly with soap and water iii Rinse thoroughly with water iv Fill out accident incident report v Contact Employee Health during office hours at 4 3675 and after hours through hospital paging 4 3411 b Eye exposure procedure i Flush eyewith water for 15 minutes ii Fill out an accident incident report iii Contact EmployeeH ealth same as above K Hazardous Drug Spills 1 A small hazardous drug spill 200 ML OR LESS may be managed by 186 obtaining a hazardous drug chemotherapy spill kit ChemoBloc from theunit or from the Pharmacy Storeroom and following the directions on the back of the kit Nurses must wear proper personal protective equipment to avoid contact with spilled material For alarge hazardous drug spill GREATER THAN 200 ML securethe area and summon the Occupational Health and Safety spill response team by calling 4 2487 during normal business hours Before 8 a m after 5 p m and on the weekends call paging for the on call hazardous waste technician Appendix M Safe Handling of Hazardous Drugs 3 For both large or small spills after absorbing free liquid with absorbent material wipe the area with a paper towel using a mild soap and water solution Dispose of decontamination material in the hazardous drug chemotherapy dis
68. arlet sodium salt 10TX Bilirubin 19N H Bio lyte 10TX Bio rad silver stain 10TX Biphenyl 10TX Biphenyl tetraamine 3 3 4 4 10TX Bipyridine 2 2 10TX Biquinoline 2 2 10TX Bis 4 fluoro 3 nitrophenol sulfone 10TX Bis 2 chloroethoxy methane O8FL Bis 2 chloroethyl ether O8FL Bis 2 chloroisopropyl ether O8FL Bis 2 ethyloxyl phthalate 10TX Bis 5 phenyloxazol 2 yl benzene 1 4 10TX Bis chloromethyl ether O8FL Bis dimethylamino benzophenone 4 4 10TX Bis trifluoroacetoxy iodobenzene 10TX Bis cydohexanone oxaldihydrazone 10TX Bismuth 11TX Bismuth chloride 11TX Bismuth chloride oxide 11TX Bismuth hydroxide 02CB Bismuth nitrate 170X Bismuth oxide 11TX Bismuth subcarbonate 11TX Bismuth subgallate 11TX Bismuth subnitrate 170X Bismuth sulfate 11TX Explosion hazard 75 Highly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Bismuth trichloride 11TX Bisphenol A 10TX Bis Tris 10TX Biuret reagent 10TX Borabicyclo 3 3 1 nonane 9 14WS Boranetetrahydrofuran complex 14WS Borax 19N H Bordeaux 11TX Boric acid 11TX Borneol 10TX Boron fluoride ether 03CA Boron nitride 11TX Boron oxide 11TX Boron trichloride 07CG Boron trifluoride 07CG Boron trifluoride diethyl etherate BF3 ether complex 14WS Boron trifluoride ethylamine complex 14Wws Boron trifluoride methanol complex 14WS Boron trifluoride propanol complex 14WS Boron tris trifluoroacetate 14WS Bouin s solution 10TX
69. assium phosphate tribasic Potassium phthalamide Potassium pyroantimonate acid Potassium pyroantimoniate Potassium pyrosulfate Potassium selenocyanate Potassium silicate Potassium silver cyanide Potassium sodium tartrate tetrahydrate Potassium sulfate Potassium sulfide Potassium sulfite Potassium superoxide Potassium tartrate Potassium tert butoxide Potassium tetraiodomercurate Il Potassium tetroxalate Potassium thiocyanate Potassium titanate PPO Pregnenolone Primuline Print flattening solution Procaine Proflavine 134 Explosion hazard H ighly reactive May form unstable peroxides on standing CPC CODE 11TX 11TX 03CA 19NH 11TX 03CA 10TX 19NH 02CB 170X 19NH 03CA 170X 170X 11TX 10TX 1555 170X 170X 170X 170X 19NH 19NH 10TX 11TX 11TX 03CA 11TX 02CB 11TX 10TX 19NH 11TX 11TX 170X 10TX 14WS 11TX 10TX 11TX 11TX 10TX 10TX 10TX 19NH 10TX 10TX Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Proline L 19N H Pronamide 10TX Propachlor 10TX Propanal Propionaldehyde O8FL Propane gas 07CG Propane sultone 1 3 10TX Propanediamine 1 2 O8FL Propanediol 1 2 O8FL Propanediol 1 3 O8FL Propanediol 2 hydroxymethyl 2 nitro 1 3 10TX Propanedithiol 10TX Propanil 10TX Propanol O8FL Propanol 2 nitro 1 O8FL Propanolol HCI 10TX Propargyl alcohol O8FL Propidium iodide 10TX Propiolactone beta O8FL Propionaldehyde O8FL Propionamide 10TX Propionanilide 10TX
70. ate Potassium arsenite solid Potassium bicarbonate hydrogen carbonate Potassium bi iodate H ydrogen iodate Potassium binoxalate Potassium biphthalate H ydrogen phthalate Potassium bitartrate Potassium borohydride Potassium bromate Potassium bromide Potassium carbonate Potassium chlorate Potassium chloride Potassium chromate Potassium citrate Potassium cyanate Potassium cyanide Potassium dichloroisocyanurate Potassium dichromate Potassium ethyl xanthate Explosion hazard H ighly reactive May form unstable peroxides on standing CPC CODE 10TX 10TX 10TX 10TX 10TX 19NH 19NH 10TX 03CA 10TX 08FL 19NH 10TX 10TX 03CA 10TX 08FL 10TX 14WS 10TX 10TX 10TX 10TX 14WS 19N H 11TX 11TX 11TX 11TX 19NH 170X 03CA 10TX 19NH 14WS 170X 19NH 19NH 170X 19NH 170X 19N H 11TX 11TX 170X 170X 10TX 133 Appendix D UAB Waste Registry CHEMICAL NAME Potassium ferricyanide Potassium ferrocyanide trihydrate Potassium fluoride Potassium gluconate Potassium hexachloroplatinate Potassium hydrogen oxalate Potassium hydrogenphthalate Potassium hydrogentartrate Potassium hydroxide Potassium iodate Potassium iodide Potassium metabisulfite Potassium nitrate Potassium nitrite Potassium nitroferricyanide Potassium oxalate monohydrate Potassium perchlorate Potassium periodate Potassium permanganate Potassium peroxymonosulfate Potassium persulfate Potassium phosphate dibasic Pot
71. be subjected to rough handling or abuse Such misuse can seriously weaken the cylinder and render it unfit for further use or transform it into a missile having sufficient energy to prope it through masonry walls To protect the valve during transportation the cover cap should be left screwed on hand tight until the cylinder is in place and ready for actual use Cylinders should never be rolled or dragged The preferred transport method even for short distances is by suitable hand truck with the cylinder strapped in place Only one cylinder 23 24 should be handled at a time After a cylinder has been relocated it must be restrained by straps chains or a suitable stand to prevent it from falling The maintenance department should be contacted to install wall brackets and chains in laboratories for securing gas cylinders 5 TRAINING 5 1 5 2 5 3 5 4 5 5 Objective To provide employees with information and training to ensure safe handling of hazardous materials in their work area Such information shall be provided at the time of an employee s initial assignment to a work area where hazardous chemicals are present before assignments involving new exposure situations Annual training is recommended Chemical hygiene officers or principal investigators are responsible for ensuring that their departmental employees are informed and trained and that all training is documented Documentation of training should be retained
72. butyric acid alpha Aminomethanol 2 Aminomethyl 3 isoxazolol 5 Aminomethylphosphonic acid A minonaphthol Aminonaphthol sulfonic acid Amino N caproic acid DL alpha Norleucine Amino N caproic acid epsilon 6 amino N hexanoic acid Amino N valeric acid DL alpha Norvaline Aminopenicillanic acid Aminophenol Hydroxyaniline Aminophenol all isomers Aminophenyl sulfone 3 Aminophenyl 4 2 6 methylbenzothiazole Amino phenylethanol mandylate 2 Aminopropionitrile beta Aminoproply morpholine N 3 Aminopropyltriethoxysilane 3 Aminopropyltriethoxysilane gamma Aminopterin Aminopyrene Aminopyridine 2 Aminopyridine 4 Aminopyrimido pyrimidine Aminopyrrolidine hydrochloride Aminosalicylic acid p Amino terbinol A mino tetramethy pi peridinyloxy Explosion hazard Highly reactive May form unstable peroxides on standing CPC CODE 10TX 03CA 10TX 19NH 19NH 10TX 10TX 10TX 10TX 08FL 10TX 02CB 02CB 10TX 02CB 10TX 10TX 10TX 08FL 03CA 08FL 10TX 10TX 10TX 03CA 03CA 03CA 03CA 10TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX 14WS 14WS 10TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX 1555 69 Appendix D UAB Waste Registry CHEMICAL NAME Aminotetrazole Aminothiophenol o Aminothiophenol p Ammonia anhydrous Ammonium acetate Ammonium benzoate Ammonium bicarbonate Ammonium bisulfate Ammonium bisulfite solid Ammonium borate Ammonium bromide Ammonium carbo
73. cetic acid methanol acetonitrile 08FL Niacinamide Nicotinamide 19NH Nickel 11TX Nickel II acetate tetrahydrate 11TX Nickel II ammonium sulfate hexahydrate 11TX Nickel II carbonate hydroxide tetrahydrate 11TX Nickel II chloride hexahydrate 11TX Nickel II chloride anhydrous 11TX Nickel II cyanide 11TX Nickel II nitrate hexahydrate 170X Nickel II oxide 11TX Nickel II phosphate 11TX Nickel II sulfate heptahydrate 11TX Nickel II sulfate hexahydrate 11TX 174 Explosion hazard Highly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Nickel carbonyl O8FL Nickel chloride hexahydrate 11TX Nickel formate 11TX Nickelous chloride 11TX Niclosamide 10TX Nicotinamide 19N H Nicotinamide adenine dinucleotide NAD 03CA Nicotinamide adenine dinucleotide phosphate 19N H Nicotine sulfate 10TX Nicotine L 10TX Nicotinic acid 19N H Nigrosin 10TX Nile blue A 10TX Ninhydrin 10TX Niobium 11TX Niobium v oxide 11TX Niobium pentachloride 14WS N iodo acetoxy ethyl N methyl amino 7 nitrobenz 2 oxa diazole 10TX Nitric acid lt 40 gt 40 fuming 16NA Nitric oxide 07CG Nitrilotri 2 propanol 1 1 1 10TX Nitrilotriacetic acid 03CA Nitrilotriethanol 2 2 2 10TX Nitro blue tetrazolium chloride monohydrate 10TX Nitro 1 2 diaminobenzene 10TX Nitro 3 trifluoromethylphenol 4 TFM 10TX Nitroacetanilide m 10TX Nitroacetanilide p 10TX Nitroacetophenone p
74. chlorine and other treatment chemicals can alter the color taste and smell of drinking water These conditions are temporary and can usually be remedied by flushing the pipes Notify maintenance if large amounts of particulates are present as this can damage fixtures 31 7 MEDICAL SURVEILLANCE AND CONSULTATION 71 7 2 Medical surveillance or consultation will be provided by The Workplace in the following situations and will be provided by or under a qualified physician 711 If an employee develops signs and symptoms associated with a hazardous chemical to which he she has been exposed 712 If environmental monitoring reveals exposure levels consistently above the action level for an OSHA regulated substance with medical surveillance requirements Formaldehyde arsenic asbestos lead benzene and ethylene oxide are among those chemicals with OSHA guidelines for medical surveillance The action levels for these chemicals are given below Arsenic 5 ug m Asbestos 0 1 fiber cc Benzene 0 5 ppm Cadmium 2 5 ug m3 Ethylene oxide 0 5 ppm Formaldehyde 0 5 ppm Lead 30 ug m 713 If an event takes place such as a spill leak direct skin contact or other occurrence that results in the likelihood of over exposure Medical surveillance may also be needed if an employee regularly works with hazardous drugs or one of the chenicals identified by the Chemical Safety Subcommittee as extremely hazardous The Department of Occupation
75. ctamethylcyclotetrasiloxane 14ws Octamethylpyrophosphoramide 10TX Octamylamine O8FL Octane O8FL Octanesulfonic acid sodium salt 1 10TX Octanethiol 1 10TX Octanoic acid 03CA Octanol 1 O8FL Octanol 2 O8FL Octanone 2 O8FL Octyl alcohol O8FL Octyl aldehyde O8FL Octyl bromide N 10TX Octyl ether 10TX Octyl sulfate sodium salt 10TX Octylamine N O8FL Octylamine tert O8FL Oil red O8FL Oil chiller Freon O8FL Oil used O8FL Oleic acid 03CA Omnifluor 10TX Omnifluor PPO 10TX Orcein 10TX Orcinol monohydrate 10TX Ordram BEC 10TX Orescein 5 maleimide 10TX Orotic acid 10TX Osmic acid Osmium tetroxide 03CA Explosion hazard 127 H ighly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME Osmium Osmium tetroxide O tolunitrile Oxabicyclo 2 2 1 hept 5 ene 2 3 dicarboxylic anhydride 7 Oxalic acid Oxalyl chloride Oxalyl hydrazide Oxethazine Oxindole Oxirane 2 2 difluoro 3 3 bis trifluoromethyl Oxone Oxydiethanethiol 2 2 Oxyquinoline sulfate Palladium Palladium II chloride 5 wt Palladium chloride 99 Palmitic acid Pancreatin Pantothenol Papain Paradione Paraffin Paraffin oil Mineral oil Paraformaldehyde Parafuchsin Paragon iodine titration indicator Paraldehyde 2 4 6 trimethyl S trioxane Paraperiodic acid Paraquat dichloride Pararosaniline hydrochloride Parathion liquid Paris green Parlodion Pelargonic acid Pe
76. cyanate 11TX Desoxycorticosterone 10TX Desyl chloride 10TX Deuterated phosphoric acid 03CA Deuterium chloride 03CA Dexpanthenol 10TX Dextran T 70 19NH Di adenosine 5 pentaphosphate 19NH Di ethylene glycol 08FL Di propylene glycol 10TX Diacetin 08FL Diacetone acrylamide 10TX Diacetone alcohol 08FL Explosion hazard 89 Highly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Diacetyl monoxime 10TX Diactamide 10TX Diallyl phthalate liquid O8FL Diallylamine O8FL Diamidine 2 phenylindite dihydrochloride 4 6 10TX Diamino 1 methyl 4 isopropylcyclohexane 1 alpha OSFL Diaminoacridinehydrochloride 3 6 10TX Diaminobenzene 10TX Diaminobenzidine 10TX Diaminobenzidine tetrahydrochloride 3 3 10TX Diaminobutane dihydrochloride 1 4 10TX Diaminobutane 1 4 10TX Diaminobutyl phosphonic acid 1 4 10TX Diaminocyclohexane trans 1 2 O8FL Diaminodiphenylether 4 4 10TX Diaminodiphenylmethane p p 10TX Diaminodipropylamine 3 3 O8FL Diaminododecane 1 12 O8FL Diaminoethyl phosphonic acid 1 2 10TX Diaminohexane 1 6 O8FL Diaminopentane 1 5 02CB Diaminophenol dihydrochloride 2 4 03CA Diaminopropane 1 3 08FL Diaminopropylphosphonic acid 1 3 10TX Diaminotoluene 2 4 10TX Diamylamine O8FL Dianisidine 10TX Dianisidine tetrazotized 10TX Diastase of malt 19N H Diazabicyclo nonene 10TX Diazald 10TX Diazinon 10TX Diazomethane 07CG Dibenz a h anthr
77. cylate 10TX Methyl silicate 10TX Methyl stearate 10TX Methyl sulfide O8FL Methyl sulfoxide 10TX Methyl tert butyl ether O8FL Methyl vinyl ether 15SS Methyl violet 10TX Methyl violet 2B 10TX Methyl yellow 10TX Methyl 1 4 naphthoquinone 2 10TX Methyl 1 butanol 2 O8FL Methyl 1 butanol 3 O8FL Methyl 1 pentyn 3 ol 3 O8FL Methyl 1 phenyl 2 pyrazolin 5 one 3 10TX Methyl 1 propanol 2 isobutyl alcohol O8FL Methyl 2 2 4 trimethyl 3 oxovalerate 10TX Methyl 2 4 pentanediol 2 10TX Methyl 2 benzothiazlinone hydrazone hydrochloride 3 10TX Methyl 2 butanone 3 O8FL Methyl 2 butene 2 O8FL Methyl 2 hexanol 2 O8FL M ethyl 2 hexanone 5 O8FL M ethyl 2 methyl 2 norborane carboxylate 10TX Methyl 2 nitro 1 3 propandiol 10TX Methyl 2 pentanol 2 O8FL Methyl 2 pentanol 4 O8FL M ethyl 2 pentanone 4 isopropylacetone O8FL Methyl 2 pentanone 4 methyl isobutyl ketone O8FL Methyl 2 propanethiol 2 O8FL Methyl 2 pyrollidone 1 O8FL Methyl 2 pyrrolidinone N O8FL Methyl 2 thiouracil 6 10TX Methyl 3 butyn 1 ol 2 O8FL Methyl 4 piperadone 1 10TX Methyl 5 acetylsalicylate 10TX Methyl 5 nitroaniline 2 10TX Methylacetophenone p O8FL Methylal O8FL Methyl alpha D mannopyranoside O8FL M ethylamindacetaldehyde 10TX M ethylamine hydrochloride 10TX M ethylamine anhydrous gas 07CG Methylamine aqueous solution O8FL Methylaminoethanol N O8FL 120 Explosion hazard H ighly reactive May form unstable peroxides on standing
78. d Health Administration OSHA in 29 CFR 1910 1450 Occupational Exposure to Hazardous Chemicals in Laboratories full text may be found at http www osha slc gov O shStd data 1910 1450 html The required elements of the plan are Standard Operating Procedures Criteria for Exposure Control M easures Fume H oods and Protective Equipment Information and Training Circumstances Requiring Prior A pproval M edical Consultation and Examination Chemical H ygiene Officer Work with Extremely H azardous Substances Appendix J contains an outline for a laboratory specific CHP Each principal investigator or clinical laboratory director should ensure that each area under their supervision is covered by a CHP that covers all aspects of chemical use in that area Procurement 4 2 1 4 2 2 4 2 3 4 2 4 All chemical purchases should be requested by the department chairperson or principal investigator and processed through the UAB Purchasing Department Material Safety Data Sheets must accompany all initial incoming shipments of hazardous chemicals Before ordering a new chemical lab or clinic personnel should obtain information on proper handling storage and disposal methods for that chemical All chemicals should be dated when received and when opened Chemicals more than two years old should be considered for disposal 17 18 4 3 4 4 4 2 5 Some chemicals may require prior approval a Select Agent Registration number
79. d hydrate 170X Phosphoramidite t 10TX Phosphoric acid 03CA Phosphoric acid meta H PO3 03CA Phosphoric anhydride 14WS Phosphorous acid H 3PO3 03CA Phosphorous oxychloride 14WS Phosphorous pentachloride solid 14WS Phosphorous pentoxide 14ws Phosphorous tribromide 14WS Phosphorous trichloride 14WS Phosphorous trisulfide O9FS Phosphorus amorphous red 14WS Phosphorus white or yellow in water 14WS Phosphorylase kinase 19NH Phosphotungstic acid hydrate 03CA Photographic activator 10TX Photographic developer 02CB Photographic fixer 10TX Photographic stabilizer 10TX Phthalaldehyde 10TX Phthalic acid 10TX Phthalic acid dipotassium salt 10TX Explosion hazard 131 Highly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME Phthalic acid diisobutyl ester Phthalic anhydride Phthalimide Phthalonitrile 1 2 dicyanobenzene Phthaloyl dichloride Phyloxide Physostigmine Eserine Phytohenagglutinin M Picoline Picolinic acid Picolinic acid hydrochloride Picolitein xylol 1 1 Picramic acid sodium salt Picric acid Picric acid 10 solution in water Picric acid wet Picryl sulfonic acid Picrylsulfonic acid sodium salt Pilocarpine Pimelic acid Pimelonitrile Pinacolone Pinene alpha Pinene beta Piperazine diethylenediamine Piperazinebis ethanesulfonic acid 1 4 PIPES Piperazinecarboxaldehyde 1 Piperidine Piperonal Piperonyl butoxide Pivalic
80. d in a zip lock plastic bag The bag should be clearly labeled as a hazardous drug with proper disposal instructions The bag or drug will also contain an instruction label which states HAZARDOUS DRUG REFER TO SAFE HANDLING PROCEDURES DISPOSE OF PROPERLY 3 The nurses station should be considered a clean area No potentially contaminated material should be brought into the nurses station 4 To avoid alarm or misunderstanding patients should be informed that any protective equipment in use is necessary for workers to be protected against the directly irritating effects of the drugs to eyes and skin see Patient Education Patient Education 1 Prior to administration of hazardous drugs in the hospital or upon discharge appropriate health care personne should inform patients of the long term as well as the short term effects of the medication being prescribed Nurses should always ask if this counseling has been provided 2 Appendix M Safe Handling of Hazardous Drugs Family members should also be instructed on the specific hazards and should be discouraged from eating in the rooms of patients who are receiving therapy involving hazardous drugs C Intravenous Drug Administration 1 Wash hands before donning personal protective equipment and after administration of a hazardous drug Personal protective equipment should consist of a disposable protective outer garment lint free and impervious such as a closed front typ
81. darified by the OSHA Hazard Communication Standard 29CFR 1910 1200 120 In order to provide recommendations consistent with current scientific knowledge OSHA has published new expanded informational guidelines dealing with controlling exposure to hazardous drugs in addition to cytotoxic agents A summary of the background data and a complete listing of references are included at the end of these procedures for your review The following criteria for deeming a drug as hazardous were developed by the American Society of Hospital Pharmacists and were used as the basis for the new guidelines e genotoxicity carcinogenicity e teratogenicity or infertility impairment serious organ or other toxic manifestation at low doses in experimental animals or treated patients e investigational drugs On direct contact some of these drugs may cause irritation to the lungs skin eyes and mucous membranes that can advance to ulceration and necrosis of tissue Handling of these materials without special personal protective equipment or containment procedures could spread potentially carcinogenic material to others Toxicity of many of these pharmaceuticals dictates that the exposure of medical personnel to these drugs should be minimized Direct Exposure is defined as direct skin contact eye contact or direct inhalation of particles or aerosols Exposure can occur during aerosol administration of a drug when handling tablets or capsules removing a
82. dithiocarbamic acid silver salt 11TX Diethylene glycol monoethyl ether acetate O8FL Diethylene triamine 02CB Diethylhydrazine 1 2 15SS Diethylhydroxylamine N N O8FL Diethylmethylamine 2 2 dichloro 10TX Diethyl m nitroaniline N N 10TX Diethyl N N diphenylurea N N 10TX Diethyloxadicarbocyamine iodide 3 3 10TX Diethyl p nitrosoaniline N N 10TX Diethylstilbesterol U S P 10TX Diethyltoluenediamine 10TX Difluoro 2 4 dinitrobenzene 1 5 15SS Difluoro 3 3 dinitrodiphenyl sulfone 4 4 10TX Difluorobenzene m O8FL Digitonin 10TX Diglycidyl ethanol O8FL Diglycidyl ether of propylene glycol 10TX Diglycol stearate 10TX Diglycolic acid 03CA Diglycostearate 10TX Diglyme 08FL Digoxin 10TX Dihexylamine 10TX Dihydroanthracene 9 10 10TX Dihydrophenanthrene 10TX Dihydropyran 3 4 Dihydro 2H pyran 08FL Dihydrosafrole 10TX Dihydrothymine 19NH Dihydroxy 1h purine 2 4 6 3h trione 7 9 10TX Dihydroxy 2 mercaptopyrimidine 4 6 03CA Dihydroxy 2 propanone 1 3 10TX Dihydroxy 4 methoxyisoflavone 5 7 10TX Dihydroxy 6 6 dinaphyl disulfide 2 2 10TX Dihydroxy 6 methylpyrimidine 2 4 10TX Dihydroxyacetone dimer 1 3 DHA dihydroxy propanone 10TX Dihydroxyacetophenone 2 4 10TX Dihydroxy alpha methylamino methyl benzyl alcohol 10TX Dihydroxybenzaldehyde 2 4 10TX Dihydroxybenzene disulfonic acid disodium salt 03CA Dihydroxybenzoic acid all isomers 03CA 94 Explosion hazard Highly reactive May form unstable per
83. e Diphenylcarbazone Diphenylcarbohydrazide 1 5 Diphenylcarbonyl chloride Diphenylchlorophosphate Diphenylchlorophosphine Diphenylethylamine 1 2 Diphenylethylene 1 1 Diphenylhydantoin 5 5 Diphenylhydantoin sodium salt Diphenylhydrazine hydrochloride 1 1 Diphenylhydrazine 1 2 hydrazobenzene Diphenylmethane Diphenyl propanedione Diphenylsemicarbazide 4 4 Diphenylsilanediol Diphenylsulfone Diphenylthiocarbazone Diphenylthiourea Diphenylurea 1 3 carbanilide Dipicrylamine Dipropylamine Dipropylaniline N N Dipyridyl dihydrate Dipyridyl 2 2 Dipyrone Disodium ethylenediaminetetraacetic acid Disodium methyl arsenate Di t butyl malonate Di t butyldiperphthalate Di t butyl p cresol 2 6 Di tert butyl 4 methyl phenol 2 6 Di tertbutylbenzene 1 4 Dithiazanine Dithiobis 2 nitrobenzoic acid 5 5 Dithiobiuret 2 4 Dithiooxamide Dithiosalicylic acid 2 2 Dithioterephthalic acid Dithiothreitol Explosion hazard H ighly reactive May form unstable peroxides on standing CPC CODE 03CA 10TX 10TX 10TX 10TX 10TX 10TX 14WS 10TX 10TX 14WS 14WS 10TX 10TX 08FL 10TX 10TX 1555 10TX 10TX 10TX 10TX 14WS 10TX 10TX 10TX 08FL 1555 08FL 08FL 10TX 10TX 10TX 10TX 11TX 08FL 10TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Dithizone diphenylthiocarbazone 10TX Divinylbenzene m O8FL DL serine 19N H
84. e building is hazardous This level should be used as a guideline that helps maximize comfort for all occupants Carbon Dioxide Levels 250 350ppm Normal outdoor ambient concentrations 600 ppm Minimal air quality complaints 600 1000ppm Not easily interpreted 1000 ppm Indicates inadequate ventilation and complaints such as headaches fatigue and eye and throat irritation will be more widespread 1000 ppm should be used as an upper limit for in door levels 6 4 6 3 3 2 Other Common Contaminants The following levels are within ACGIH TLVs for contaminants commonly used for indoor air quality screening Carbon monoxide 0 25 ppm Formaldehyde 0 0 5 ppm Nitrogen dioxide 0 3 ppm Ozone 0 0 1 ppm Total hydrocarbons 0 2 ppm Water Quality Testing All water on campus is supplied by the City of Birmingham Water Works The quality of the water is consistently well within the Environmental Protection Agency s guidelines for drinking water However if there is concern that a chemical contaminant is present in the water Chemical Safety can arrange for sample collection and testing The Water Works and the Jefferson County Health Department can also perform tests on the drinking water supplied to the University Certain activities such as fire hydrant testing construction or plumbing modifications can cause discoloration of the water or release of unusual amounts of particulates into the water Changes in the amount of
85. e F G n a P Diethanolamine F E n a E Diethyl ether F G E P Dimethyl sulfoxide n a n a n a n a Ethyl acetate F G G F Ethylene dichloride P F G P Ethylene glycol G G E E Ethylene trichloride P P n a P Fluorine G G n a G Formaldehyde G E E E Formic acid G E E E Glycerol G G E E Hexane P E n a P Hydrobromic acid 40 G E n a E 160 Appendix G Protective Gloves Hydrochloric acid G G G E Hydrofluoric acid 30 G G G E Hydrogen peroxide G G G E lodine G G n a G M ethylamine G G E E M ethyl cellosolve F E n a P M ethyl chloride P E n a P M ethyl ethyl ketone F G G P M ethylene chloride F F G F M onoethaloamine F E n a E Morpholine F E n a E N aphthalene G G E G Nitric acid P R P G Perchloric acid F G F E Phosphoric acid G E n a E Potassium hydroxide G G G E Propylene dichloride P F n a P Sodium hydroxide G G G E Sodium hypochlorite G P F G Sulfuric acid G G F G Toluene p F G F Trichloroethylene P F G F Tricresyl phosphate P F n a F Triethanolamine F E E E Trinitrotoluene P E n a P Aromatic and halogenated hydrocarbons will attack all types of natural and synthetic glove materials Should swelling of the glove occur the user should change to fresh gloves and allow the swollen gloves to dry and return to normal No data on the resistance to dimethyl sulfoxide of natural rubber neoprene nitrile rubber or vinyl materials are available the manufacturer of the substance recommends the use of butyl rubber gloves
86. e administration or preparation of hazardous drugs These containers and the yellow barrels are handled in the medical waste program 11 1 2 Chemicals should not be disposed of through the red waste barrel system designed for medical waste to be microwave sterilized and shredded 11 1 3 Certain materials such as batteries pesticides and fluorescent bulbs and ballasts must be disposed of as universal waste See section 12 The UAB Chemical Waste Management Program is designed to achieve three goals 11 2 1 Protection of the health and safety of the campus community as well as surrounding communities 43 44 11 2 2 11 2 3 Proper training evaluation packing and labeling protects the health and safety of employees handling hazardous chemicals as well as others who might come in contact with them during the disposal process Reduction of chemical waste in laboratories and other facilities The volume of chemical waste generated at UAB can be reduced by 11 2 2 1 Recovery of certain high purity solvents through distillation 11 2 2 2 Reuse of many flammable solvents for fuels 11 2 2 3 Disposal of non hazardous waste separately from hazardous chemical waste 11 2 2 4 Recycling unused chemicals in teaching and research laboratories 11 2 2 5 Procedures to render hazardous chemical waste non hazardous Compliance with federal state and local regulation Policy at the University of Alabama at Birmingham is to main
87. e being used and being disposed of before being over filled BSM App J sec I F Medical waste is being separated from non medical waste at the point of generation BSM 11 1 3 Revised 04 29 2002 THE UNIVERSITY OF LKR ALABAMA AT BIRMINGHAM The Department of Occupational Health and Safety Dear Dr h Subject Recent Lab Audit We appreciate the cooperation and courtesy of you and your staff during the audit of your laboratory Hazard surveillance is an ongoing process The fact that specific hazards may not have been identified during this audit does not lessen their seriousness or their need to be addressed Corrective action is required for Key responses Sections B through E of the attached Audit Checklist and a written response of corrective actions taken or plan of action is requested within 45 days from the date of inspection The written response may be sent via e mail dsw uab edu or campus mail by forwarding to Occupational Health and Safety Ch 19 Room 445 2041 If I can assist you in making these corrections please call 934 2487 Occupational Health and Safety Representative Date of Audit Lab Representative List all staff working in this lab and Y the appropriate box to indicate that the staff member has received documented laboratory safety training and if applicable been offered the Hepatitis B vaccination Tb screening or Tetanus vaccination Employee Name Safety training Hepatitis B Tb screen
88. e gown with long sleeves and knit cuffs Cuffs must be tucked under gloves Two pair of powder free disposable latex gloves or one pair of the thicker chemotherapy type administration gloves should be worn during those procedures where leakage of the drug may result i e removing air bubbles from syringes and IV tubing injecting drugs disconnecting IV tubing fixing leaking tubing or syringe connections Gloves and gowns that become contaminated or torn should be changed immediately Splash protection for the eyes such as a face shield or safety goggles and mask should be worn when administering hazardous drugs under pressure or if aerosol generation is possible Infusion sets and pumps which should have luer loc fittings whenever possible should be watched for signs of leakage during use A plastic backed absorbent pad should be placed under the tubing during administration to absorb any leakage Always use an appropriate size needle since the larger gauge needles are more likely to drip Prime IV sets or expel air from a syringe by placing a sterile gauze pad near the needle tip when the air is expelled Preferably a plastic bag should be used as a receptacle Priming should be done at a designated workstation or in the patient s room at bedside not at the nurse s station so other staff are not exposed in the event of accidental spillage The plastic bag and gauze pad should be discarded into the hazardous drug chemotherapy waste c
89. e triphosphate 10TX Inosine 5 triphosphate 10TX Inositol 19NH Insulin 19NH Inulin 19N H lodic acid 170X lodine 11TX lodine monochloride 03CA lodoacetamide 10TX lodoacetamide 2 10TX lodoacetamido anilino naphthalene 6 sulfonic acid 10TX lodoacetamido anilino 6 sulfonic acid 2 4 10TX lodoacetamidoethyl amino naphthalene 1 sulfonic acid 5 10TX lodoacetamidofluorescein 6 10TX lodoacetamidosalicylic acid 5 10TX lodoacetic acid 03CA lodobenzene 08FL lodobenzoic acid 10TX lodobiphenyl 4 10TX lodobutane 08FL lododecane 1 08FL lodoform 10TX lodomethane 10TX lodonitrotetrazolium violet formazan p 10TX lodopropene 3 allyliodide 08FL Explosion hazard 111 H ighly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE lodopropionic acid beta 03CA lodotoluene o 08FL lodotrimethylsilane 14WS lonox 20 antioxidant 10TX Iridium 11TX Iron 11TX Iron III acetylacetonate 10TX Iron III iodide 11TX Iron dextran 11TX Iron hematoxylin 11TX Iron II sulfate 11TX Iron oxide saccharated 11TX Iron pentacarbonyl 08FL Iron phosphate 11TX Iron IIl perchlorate 15SS Isatin 10TX Isatin o aminobenzoyl formic anhydride 10TX Isethionic acid ammonium salt 10TX Isethionic acid sodium salt 10TX Isoamyl acetate 08FL Isoamyl alcohol OSFL Isoamyl nitrate 170X Isoamylamine O8FL Isoborneol 10TX Isobutanol isobutyl alcohol 08FL Isobutyl acetate O8FL Isobutyl alcoh
90. eagent 11TX Magnesium sulfate 19N H Magnesium sulfide 11TX Magnesium metal 14WS Malachite green oxalate 10TX Malathion 10TX Maleic acid hydrazide 10TX Maleic acid 03CA Maleic anhydride 03CA Malic acid 10TX Malic dehydrogenase 19NH Malonaldehyde 10TX Malonaldehyde bis diethyl acetal O8FL Malonaldehyde bis dimethyl acetal O8FL Malonamide 10TX Malonic acid 10TX Malonic ester O8FL Malononitrile O8FL Malonyl dichloride 14WS Maltose monohydrate D 19N H Mandelic acid 10TX Maneb 09FS Manganese 14WS Manganese II carbonate 11TX Manganese II chloride anhydrous 11TX Manganese II chloride tetrahydrate 11TX Manganese II nitrate hexahydrate 170X Manganese II nitrate hydrate 170X Manganese II sulfate hydrate 11TX Manganese II sulfate monohydrate 11TX Manganese III oxide 11TX Manganese chloride 11TX Manganese dioxide O8FL Mannitol D 19NH Manzate 09FS Marble s reagent 10 cupric sulfate 50 H CI 03CA Martius yellow 10TX MDI Methylene bis phenyl isocyanate 14WS Megasul N N dinitrodipheny disulfide 10TX Meglumine diatrizoate 10TX Melamine 10TX Melphalan 10TX Menthol DL O8FL Mercapto 1 2 propanediol 3 O8FL Mercapto 4 methylthiophenol 2 10TX M ercaptoacetic acid 03CA 116 Explosion hazard Highly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME Mercaptobenzoic acid Mercaptobenzothiazole 2 Mercaptoethanol 2 M ercaptoethylamine hydrochloride
91. emical disinfection before disposal 5 Are sharps containers sealed when fill to manufacturers recommended fill line and placed in designated red plastic barrels with covers 6 Is autoclave performance periodically validated using biospore strips or ampules 7 In areas using Class 2 or 3 etiologic agents is the principal entrance to the work area posted with an 8 x 10 or equivalent biohazard sign specifying agent s 8 Is equipment used for infectious material storage and processing posted with a 2 x3 biohazard sign or equivalent 9 Is outer street clothing stored somewhere other than the laboratory area where Risk Group 2 or higher agents or allergens may be present 10 Are procedures with a potential for creating infectious aerosols or splashes conducted within a certified biological safety cabinet Location Bldg Room units Certification Date 11 Are sharps placed directly into appropriately labeled and or color coded impervious rigid puncture resistant containers with covers 12 Does the lab have access to an autoclave for decontamination BSL 2 work 13 Does the lab have access to an autoclave within the work area for BSL 3 work 14 Are work surfaces being decontaminated when work with infectious material is finished and immediately after spills or splashes 11 99 Appendix I Laboratory Safety Audit Preparation Checklist Pages ref
92. ene Carvacrol Carvone Casein Catechol Caustic soda Cedarwood oil Cellex D Cellobiose Cellosolve Cellulose acetate Ceric Cerium ammonium sulfate Cerium III sulfate octahydrate Cerium IV oxide Cerium IV sulfate Cerium IV sulfate tetrahydrate Cerium chloride Cesium chloride Explosion hazard H ighly reactive May form unstable peroxides on standing CPC CODE 10TX 10TX 08FL 08FL 03CA 10TX 03CA 10TX 10TX 08FL 08FL 10TX 10TX 08FL 07CG 10TX 10TX 19NH 19NH 14WS 07CG 07CG 02CB 19N H 10TX 11TX 10TX 10TX 10TX 10TX 10TX 08FL 19NH 10TX 02CB 10TX 10TX 19NH 08FL O9FS 170X 11TX 11TX 170X 170X LITX 10TX 81 Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Cesium nitrate 170X Cesium sulfate 11TX Cetyl alcohol 10TX Cetyltrimethylammonium bromide 10TX Cevine 10TX CHAPS 10TX Chelating sepharose 19N H Chelex 100 resin 19N H Chloral 10TX Chloral hydrate 10TX Chloralose alpha 10TX Chloramine t 10TX Chloramine t hydrate 10TX Chloranil 10TX Chloranilic acid 10TX Chlordane 10TX Chloretone 10TX Chlorine 07CG Chlornaphazine 10TX Chloro 5 2 nitroaniline 10TX Chloro 1 1 diethoxypropane 3 08FL Chloro 1 naphthol 4 10TX Chloro 2 3 epoxypropane 1 08FL Chloro 2 4 dinitrobenzene 1 10TX Chloro 2 butene 1 08FL Chloro 2 methyl propane 1 08FL Chloro 2 methyl propane 2 08FL Chloro 2 methylaniline 5 08FL Chloro 2 methylphenol 4 10TX Chloro 2 methylpro
93. ene 29 6 3 2 Recommended Temperature and Humidity ene 29 6 3 3 Sample Collection eere rere tnn tnt tn tantas 30 6 4 WATER QUALITY TESTING cscseccsssssosssessocsnssnsensersesecssesessensassssssssasssonsons 31 7 MEDICAL SURVEILLANCE AND CONSULTATION nnn 33 8 PERSONAL PROTECTIVE EQUIPMENT eren nnne nnne 35 9 SPILLS AND ACCIDENTS usserenenenenenenenenenenenensnsnnnnnnensnsnsnnsnsnsnsnsnssssnsnsnsnenenenene 37 9 1 PERSONAL INJURY eren eene nennen stas tante atten senten usano sens snot rasta etna 37 92 SMALL CHEMICAL SPILLS LESS THAN 500 ML enne 37 93 LARGE CHEMICAL SPILLS 500 ML OR MORE ennt 38 94 MERCURY SPILLS RR 38 10 EMERGENCY PROCEDURES rone entente nnne 41 11 CHEMICAL WASTE MANAGEMENT cssssssssesssssnssnsnesnssnssnensensansnneanennes 43 11 1 OVERVIEW oessscscsesssssossssoseesssoocosssceccecscecsessecssesssssosesssssooeosesseeseeescerssesessoesse 43 11 2 UAB CHEMICAL WASTE MANAGEMENT PROGRAM usnsnsusnenenenensnenensnennennr 43 11 3 WASTE REDUCTION eesessessessssosscesoessssssosoesosoesensseneossessrnseeseesresessesseseennnessea 45 11 3 1 Waste Minimizalion eere rennen nennen tnnt nnne 45 11 3 2 Flammable Organic Solvents eene 45 11 33 Disposal of Chemicals Down the Sink or Sanitary Sew
94. enosine 3 5 cyclic phosphate 19N H Adenosine 5 diphosphate 19N H Adenosine 5 triphosphate 19NH A denosyl I methionine 5 19NH Adenylylimidophosphate 5 10TX Adenylyl uridine 19NH Adipamide 10TX Adiphenine hydrochloride 10TX Adipic acid 03CA Adiponitrile 1 4 dicyanobutane 08FL Adipoyl acid 03CA Adipoyl chloride 14WS Adrenalin hydrochloride 10TX Aflatoxin B 10TX Agar 19N H Agarose 19N H Alanine 19N H Alcian blue 10TX Alcohol dehydrogenase 19N H Aldicarb 10TX Aldol O8FL Aldrin 10TX 66 Explosion hazard H ighly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME Alizarin Alizarin red Alizarin red S monohydrate 3 4 dihydroxy 9 10 dioxo 2 anthracene sulfonic acid sodium salt Alizarin sodium sulfonate Alizarin yellow Alizarine sodium monosulfate Alkaline phosphatase Allethrin Allopurinol Alloxan Alloxan monohydrate Allyl acetate Allyl alcohol Allyl ether Allyl isothiocyanate Allyl phthalate Allyl sulfide Allylphenol o Alpha terpineol Alphazurine blue Alpine hydride S Alpine borane S Aluminum acetate Aluminum acetylacetonate Aluminum ammonium sulfate Aluminum chloride Aluminum chloride hexahydrate Aluminum ethoxide Aluminum hydroxide Aluminum isopropoxide Aluminum nitrate Aluminum oxide Aluminum oxide acidic Aluminum oxide basic Aluminum phosphate Aluminum phosphide Aluminum potassium sulfate Aluminum propoxide Aluminum si
95. er System 46 1124 TIS ERR 46 11 3 5 Neutralization and Deactivation eese 47 11 3 6 Elimination of Non hazardous Waste eene 47 11 3 7 Solvent Recycling eere 48 11 3 8 Teaching Laboratory Samples nennen 48 114 YELLOW BARREL AND CHEMOTHERAPY WASTE nennen 48 11 4 1 Hospital Areas eese nennen nnnnnnennnenntnntenns 49 11 4 2 Non Hospital Areas eere 49 11 5 HAZARDOUS WASTE DISPOSAL eren nnn nnne nnne 49 11 5 1 Packing the Waste eese nnnnnnnnns 50 11 5 2 Completing the Manifest seen nnt 51 11 5 3 Chemical Waste Removoal renes 52 12 UNIVERSAL WASTE uses A EEEE EEEE E 53 121 COMPLETING THE UNIVERSAL WASTE MANIFEST rrr 53 APPENDICES 55 A ee 55 B SHOCK SENSITIVE AND WATER REACTIVE COMPOUNDS 59 C CHEMICAL PACKING CODES 21 rere rne 63 D CHEMICAL REGISTRY ssussnsenesnssnenusnsenesnsenessensenensensensnnsnssnunnsnusnsenssuusnene 65 E WASTE MANIFESTS ssssssscsssssssssorsvossssscncsarsscssssssucssessssensensessanensenssessneses 155 F ACCIDENT INCIDENT REPORT FORM eren 157 G PROTECTIVE GLOVES u0srosusouosusensssensensensenensensssenssnssssnsen
96. erating facility The HMF stocks appropriate labels that can be completed by those packing the waste A manifest must be completed as with hazardous waste Directions for completing the Universal Waste M anifest are found on the back of the form When managing Universal Waste it is critical not to separate mercury from thermometers manometers and other mercury containing devices Doing so generates a hazardous mercury waste The same is true of lead acid batteries The acid must not be drained If separated the acid becomes a hazardous waste and the person draining the battery is permanently responsible for the hazardous waste generation Each type of universal waste should be boxed separately Pesticides should be packed with other pesticides not with ballasts Batteries of the same type but different sizes may be packed together AA and D dry cell batteries may be placed in the same box however NiCad and lithium batteries should be boxed separate from one another 12 1 Completing the Universal Waste M anifest A manifest must be completed and attached to each box These may be obtained from OH amp S or the OH amp S website Personne need to complete the manifest by following the directions below 12 1 1 Laboratory Information Fill in the generator name i e maintenance supervisor chemical safety coordinator telephone number department building room number and the date 53 12 1 2 Waste Information Each container must
97. erenced for the Biosafety Manual Chemical Safety and Waste Management Manual and the General Health and Safety Management Program provide more information on topics A current chemical inventory is available CSWMM Sec 4 3 and GHSMP p 74 A list of microbial agents being used in the laboratory BSM Sec 11 3 A list of rr DNA RNA Host Vectors being used in the laboratory Material Safety Data Sheets are available or have been requested for all hazardous materials CSWMM Sec 4 4 Records of waste disposal through the HMF are available CSWMM Sec 11 5 3 Records of personnel safety training are kept BSM Sec 11 3 and CSWMM Sec 4 6 4 Records of participation in an occupational medicine program if working with animals BSM 11 3 A laboratory specific safety plan has been written BSM Sec 11 3 and CSWMM Sec 4 1 Required signs posted for special hazards biohazard carcinogen select agents etc CSWMM Sec 3 2 2 and 4 5 4 Emergency phone numbers are posted correctly Template and printing instructions are available on the Department of Occupational Health and Safety website Chemical Safety section Stickers should be posted on doors and near phones CSWMM Sec 4 5 5 and GHSMP p 61 Aisles and hallways are clear of equipment and other obstructions CSWMM Sec 3 1 and GHSMP p 44 All compressed gas cylinders are chained to walls or counters those not in use have the protective cover in place CSWMM Sec 4 7 4 5
98. es the peracetic acid reacts with the organic material in the dialysis waste stream to produce a non hazardous waste 11 3 5 Neutralization and Deactivation Certain hazardous chemical wastes can be rendered non hazardous by specific neutralization or deactivation laboratory procedures Contact the Chemical Safety Director to see if the waste you generate is suitable for neutralization Procedures for deactivating ethidium bromide are found in Appendix K 11 3 6 Elimination of Non hazardous Waste from Hazardous Waste The following items are not considered hazardous They should be collected in disposable containers or plastic bags clearly labeled as non hazardous waste and put in the wastebasket All compounds identified by the two letter code NH are non hazardous and should not be disposed of via the chemical waste program unless they are components of a mixture with hazardous materials or are suitable for chemical recycling Non hazardous Waste 11 3 6 1 Organic Chemicals Acetates Ca Na NH4 and K Amino acids and their salts Citric acid and salts of Na K Mg Ca and NH4 Lactic acid and salts of Na K Mg Ca and NH4 Sugars Glucose lactose fructose sucrose maltose 11 3 6 2 Inorganic Chemicals Bicarbonates Na K lodides Na K Borates Na K Mg Ca Oxides B Mg Ca Al Si Fe Bromides Na K Phosphates Na K Mg Ca NH4 Carbonates Na K Mg Ca Silicates Na K Mg Ca 47 48 Chlorides
99. exposure recommended for an employee in a normal 8 hour day for a 40 hour workweek These values are recommended by the American Conference of Governmental Industrial Hygienists ACGIH but are not legal exposure limits Universal Waste Universal wastes are hazardous wastes commonly generated by households businesses and industries EPA designates pesticides batteries fluorescent bulbs and thermostats as universal wastes Regulations for handling these wastes are in general less stringent than if they were managed as hazardous wastes 57 Appendix B Highly Reactive Compounds These compounds require special handling Call the Hazardous and Regulated Materials Manager for special instructions A partial list of these compounds is given below Shock Sensitive Compounds These compounds may explode if subjected to friction or shock Acetylides Azides Diazo compounds Diethyl and isopropyl ether when peroxides are present H alamines Nitro compounds Nitrocellulose Nitrogen triiodide Nitroso compounds Organic nitrates Organic peroxides Perchlorate salts especially those of heavy metals such as ruthenium and osmium Peroxidizable chemicals Picric acid and picrate salts Polynitroaryl compounds Powdered metals Water Reactive Compounds These materials may react violently with water Alkali metals Na Li K Alkyl lithium compounds e g butyl lithium Anhydrous aluminum chloride Boron trifluoride Chlo
100. fluoroacetic anhydride 14ws Trifluoroacetylacetyl naphthalene 2 10TX Trifluoroethanol 2 2 2 O8FL Trifluoroethylamine hydrochloride 2 2 2 14WS Trifluoromethanesulfonic acid 03CA Trifluorotoluene alpha alpha alpha O8FL Triglyme O8FL Trihydroxybenzoic acid monohydrate 2 4 6 10TX Trihydroxydecanophenone 2 3 4 10TX Trihydroxyflavone 4 5 7 Apigenin 10TX Triisopropyl phosphite O8FL Triketohydrindene hydrate 1 2 3 Ninhydrin 10TX Trimellitic acid 1 2 4 Benzenetricarboxylic acid 14WS Trimethoxyacetophenone 3 4 5 10TX Trimethoxybenzoic acid 3 4 5 03CA Trimethyl acetic anhydride 14WS Trimethyl orthoformate O8FL Trimethyl pentane 2 2 4 O8FL Trimethyl phenol 2 4 6 03CA Trimethyl phosphate 08FL Trimethyl phosphite O8FL Explosion hazard 149 H ighly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Trimethyl 1 3 pentanediol 2 4 4 OSFL Trimethyl 1 pentanol 2 2 4 O8FL Trimethylacethydrazine ammonium chloride 10TX Trimethylacetyl chloride 14WS Trimethylamine aqueous solution O8FL Trimethylamine hydrochloride O8FL Trimethylbenzene 1 2 4 O8FL Trimethylchlorosilane Chlorotrimethylsilane 14WS Trimethylpyridine 2 4 6 O8FL Trimethylsilyl diethylamine TMSDEA O8FL Trimethylsilylacetamide N O8FL Trimethylthiophenol 2 4 6 10TX Trimyristin 10TX Tri N butylphosphine O8FL Trinder s reagent contains ferric chloride 11TX Trinitro 9 fluorene 2
101. fume hood by personnel observing general laboratory safety precautions and wearing appropriate personal protective clothing 1 Dilute solutions containing ethidium bromide to a concentration of less than 0 05 w v 50 mg 100 ml 2 For each 100 ml of ethidium bromide solution add 20 ml of fresh 596 hypophosphorous acid and 12 ml of fresh 0 5 M sodium nitrate solution Check the pH of the solution to make sure it is less than 3 0 Stir briefly 3 Allow the solution to react for at least 20 hours neutralize with sodium bicarbonate and rinse down the sanitary sewer Lunn G and Sansone E 1994 Destruction of Hazardous Chemicals in the Laboratory John Wiley amp Sons Inc pp 185 177 Appendix L Management of Photographic C hemicals Photographic chemicals are used extensively on campus and can be bought in liquid form which only need diluting or powder form which need dissolving and diluting or as prefilled kits for use in automatic processing equipment Handling of these materials may be limited to changing sealed containers or may involve the use of large open trays of chemicals 6 7 Hazards Developer solutions and powders are often highly alkaline and glacial acetic acid used in making the stop bath is corrosive by skin contact inhalation and ingestion Developer powders are highly toxic by inhalation and moderately toxic by skin contact dueto the alkali and developers themselves Develope
102. have its contents identified on the manifest Select all types of materials to be picked up Describe the contents as liquid or solid and specify the number of pounds of each type of item List the number and type of container Container types include cardboard box BF and cardboard drum DF Bulbs Should be packed to avoid braekage in their original containers or in the special recycling drums Batteries thermostats and containers of pesticides should be placed in sturdy cardboard boxes 12 1 3 The generator should check the information on the manifest sign his or her name and attach it to the corresponding container To have universal waste removed mail the top copy of the manifest to the address below HAZARDOUS MATERIALS FACILITY HMF 221 14th Street South UAB Campus Mail 0001 Attach one copy to the box and retain a copy for the department records Specify where the waste is to be picked up Waste containers should be stored in areas where they will not be damaged by inclement weather Ensure that HMF personne will have access to the waste holding area If your waste is not picked up in a reasonable period of time call 4 3797 to inquire about the delay Appendix A Glossary Acute An adverse effect with symptoms of high severity coming quickly to a crisis Alabama Department of Environmental Management ADEM The state agency with direct oversight of hazardous material management at UAB Carcinogen A sub
103. he following are conditions for chemical transport in elevators 48 61 Chemicals should be labeled and carried in secure break resistant containers with tight fitting caps The packing systems supplied by manufacturers for shipping are excellent at preventing breakage during transport and may be reused for this purpose 4 86 2 The individual transporting the hazardous chemicals should operate the elevator alone whenever possible The safe transport of small quantities of flammable liquids should include provisions that include the use of rugged pressure resistant non venting containers storage during transport in a well ventilated vehicle and elimination of potential ignition sources If there is a spill or accident one should contact the Hazardous Materials Manager at extension 4 3797 state his or her name telephone number location of incident the name and quantity of material involved and the extent of injuries if any Take all necessary emergency measures such as removing contaminated clothing washing any chemicals from the skin with soap and water and seeking prompt medical attention If it is necessary for the individual transporting the chemicals to leave the scene of an accident or spill he she should delegate someone to remain at the scene until emergency personne arrive The responsible party should return as soon as possible Cylinders that contain compressed gases are primarily shipping containers and should not
104. hin three to five minutes Complete the Accident Injury Report Form Appendix F and send any cases of non life threatening injury or suspected injury to The Workplace 2151 Highland Avenue Birmingham AL 35205 Injuries appearing to present immediate danger to life or limb should be transported to the University Hospital Emergency Department Small Chemical Spills Less than 500 ml 9 2 1 9 2 2 Promptly clean up small spills using appropriate protective apparel and equipment Consult the MSDS for any special precautions needed A spill kit should be available These may be ordered from scientific and safety supply vendors or may be made up by lab personne A basic spill kit should indude latex surgical gloves safety glasses or goggles disposable lab coats aprons or gowns paper towels spill booms or pillows vermiculite a small disposable plastic broom and dust pan zip loc bags plastic garbage bags and a small bottle of detergent cleaning solution Spill kit supplies may be stored in a buck that can be used to contain the waste generated in the dean up Small spills can be absorbed using paper towels spill pillows or vermiculite Absorbent materials must generally be disposed of as chemical waste unless the spilled material can be evaporated in a properly functioning fume hood or neutralized before clean up 37 38 9 3 9 4 92 3 Spills of powdered chemicals should be carefully swept up and contained Avoid vigo
105. hloroethane 1 1 1 2 O8FL 144 Explosion hazard H ighly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME Tetrachloroethane 1 1 2 2 Tetrachloroethylene Tetrachloroethene Tetrachloromethane Tetrachloro p benzoquinone 2 3 5 6 Chloranil Tetrachlorophenol all isomers Tetrachlorophthalic anhydride Tetrachlorosilicon Tetracyanoethylene Tetradecane Tetradecanol 1 Tetradecylamine Tetraethoxypropane 1 1 3 3 Tetraethyl orthosilicate Tetraethyl pyrophosphate Tetraethylammonium bromide Tetraethylammonium chloride Tetraethylammonium hydroxide 20 in water Tetraethylammonium perchlorate Tetraethylenepentamine Tetraethyllead Tetrafluoroboric acid Tetrafluorophenol 2 3 5 6 Tetrahydro 4H pyran 4 one Tetrahydrobenzaldehyde 1 2 3 6 Tetrahydrodicyclopentadiene Tetrahydrofuran Tetrahydrofurfuryl alcohol Tetrahydroisoquinoline 1 2 3 4 Tetrahydronaphthalene 1 2 3 4 Tetrahydroxy 1 4 quinone hydrate Tetrahydroxyanthraquinone disodium salt Tetrahydroxynaphthalene 1 2 3 4 Tetralin Tetrahydronapthalene Tetralol alpha 1 2 3 4 Tetrahydro 1 naphthol Tetramethoxypropane 1 1 3 3 Tetramethyl 1 4 benzoquinone Duroquinone Tetramethylammoni um borohydride Tetramethylammonium chloride Tetramethylammonium hydroxide Tetramethylammonium iodide Tetramethylammonium iodine Tetramethylbenzene 1 2 4 5 Tetramethylbenzene 1 2 4 5 Durene Tetramethylbenzidine acid N N N
106. hlorophenyl N N dimethylurea N 3 4 Dichlorophenylarsine Dichlorophenylhydrazine hydrochloride 3 4 Dichloropropane 1 2 Propylene chloride Dichloropropanol 1 3 alpha dichlorohydrin Dichloropropene 1 3 Dichloropropionic acid 2 2 Dichloro p toluenesulfonamide Dichloropyridazine 3 6 Dichloropyridine 3 5 Dichloroquinone chloroimide 2 6 Dichloroquinone 4 7 Dichlorotoluene 2 4 Dichloro trans 2 butene 1 4 Dichlorvos DDVP Dichromoacetophenone p Dicumyl peroxide Dicyandiamide Dicyanobenzene 1 2 Dicyanopropane 1 3 Dicydohexylamine Dicyclohexylcarbodiimide N N DicyclohexyIphthalate DCHP Dicyclopentadiene 9 Explosion hazard Highly reactive May form unstable peroxides on standing CPC CODE O8FL 08FL 08FL 08FL 10TX 08FL 10TX 10TX 10TX 10TX 08FL 10TX 10TX 14WS 10TX 10TX 03CA 10TX 10TX 10TX 10TX 14WS 10TX 10TX 14WS 10TX 08FL 10TX 08FL 03CA 10TX 10TX 10TX 10TX 10TX 08FL 08FL 10TX 10TX 1555 10TX 10TX 08FL 02CB 02CB 10TX 08FL Appendix D UAB Waste Registry CHEMICAL NAME Dicydopentadienyl iron ferrocene Dicydopentamethylenethiuram disulfide Didodecyl phthalate Dieldrin Diethanolamine Diethoxyaniline 2 5 Diethoxyethanol Diethyl 1 3 acetonedicarboxylate Diethyl 3 oxoglutarate Diethyl adipate Diethyl aniline 2 6 Diethyl barbituric acid barbital Diethyl carbonate Diethyl chlorophosphate Diethyl chlorophosphite Die
107. ial Sec Home Address Gender M F Circle Employee Full time part time perm temp Student SOM SON SOD Other Visitor Date of Birth Home phone Campus Phone Campus address Job Tite INFORMATION ABOUT THE INCIDENT Date of Incident Police notified Yes No Case f Location of Incident Describe what happened how it happened factors leading to the event substances or objects involved Be as specific as possible attach separate sheet if necessary Were there any witnesses to the incident Yes No If yes attach separate sheet with names addresses and phone numbers or campus depts and phone Was the individual injured If so describe the injury laceration sprain etc the part of body injured and any other information known about the resulting injury s Was medical treatment provided Yes No Refused If so where circle Emerg Rm The Workplace Walk In Clinic Will the employee miss time from work as a result of this incident Yes No Unknown REPORTER INFORMATION Print Name of Reporter Reporter Signature Date Report Completed V April 2002 EMPLOYEE REPORTS Send to HRM in AB 360G VISITOR STUDENT to Risk Management 500 Bldg Suite 504 UAB On The Job Injury lliness Initial Medical Evaluation Authorization This form must be completed signed and presented to the medical service provider prior to receipt of treatment except in the event of a serious medical emergency A post acciden
108. iate Furthermore in case of injury or suspected injury an Accident Incident Report Form should be completed Appendix F Procuring all chemicals used in the department and the equipment needed to safely use store and handle the materials Working through the Chemical Safety Director and arranging for medical surveillance of laboratory personnel if deemed appropriate by The Workplace Ensuring that a current chemical inventory of hazardous materials is being used or stored in the laboratory or work area Cooperating with the Chemical Safety Director or his designated representative during inspection visits Hazardous and Regulated M aterials M anager Major duties or activities include the following 2 4 1 2 4 2 Ensuring the safe transport of surplus chemicals and chemical waste to the H azardous Materials Facility Ensuring the safe and legal disposal of all hazardous waste from the H azardous Materials Facility 2 5 2 6 2 7 Chemical Hygiene Officer Under the direction of the department chairperson and or the principal investigator the chemical hygiene officer is responsible for ensuring compliance with the chemical safety program within the department He she functions as a liaison with the Chemical Safety Director He she may appoint a Designee to conduct the routine duties outlined below however the chemical hygiene officer is responsible for the completion of these tasks Designee A designee a
109. ic acid ethylene glycol 10TX Hemicholinium 3 hydrate 10TX Hemocyanin 19N H Hemo DE terpene mineral oil butylated hydroxyanisole O8FL Hengar granules selenized poison 11TX Heparin 19N H HEPES 10TX Heptachlor 10TX Heptafluorobutyric acid 03CA Heptaldehyde 08FL Heptamethylnonane 2 2 4 4 6 8 8 O8FL Heptane 08FL Heptanoic acid 03CA Heptanone 08FL Heptene 1 08FL Heptylaldehyde 08FL Heptylamine N 08FL Hexabutyl stannoxane 11TX Hexachloro 1 3 butadiene 10TX Hexachlorobenzene 10TX Hexachlorocyclohexane 10TX Hexachlorocyclopentadiene 10TX Explosion hazard 107 Highly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Hexachlorodibenzo p dioxin 10TX Hexachloroethane 10TX H exachlorohexahydro endo endo dimethanonaphthalene 10TX Hexachlorophene 10TX Hexachloropropene 08FL Hexadecane 10TX Hexadecanol 1 10TX Hexadecene 1 08FL Hexadecyltrimethylammonium bromide 10TX Hexafluoro 2 propanol 1 1 1 3 3 3 02CB Hexafluoroacetone 10TX H exahydrobenzene O8FL Hexaldehyde O8FL Hexamethyl phosphoramide O8FL Hexamethyl phosphorous triamide 08FL H examethyl tetraphosphate 10TX Hexamethyldisilane 14WS Hexamethyldisilazane 1 1 1 3 3 3 14WS Hexamethyldisiloxane O8FL H examethylene diisocyanate 14ws H examethylenetetrami ne 09FS H examethylphosphoramide 10TX Hexamethyl siloxane O8FL H examine cobalt 11TX Hexanal 08FL Hexane 08FL Hexanediami ne 1 6 02CB Hexanediol 1
110. id 2 6 03CA Pyridinium bromide perbromide 170X Pyridinium chlorochlorate 170X Pyridinium chorochromate 170X Pyridoxine HCl 19N H Pyridyl thiadiazole 10TX Pyridylazo 2 naphthol 1 2 10TX Pyridylcarbinol 2 O8FL Pyrocarbonic acid diethyl ester O8FL Pyrocatechol 10TX Pyrogallate absorption solution 10TX Pyrogallic acid Pyrogallol 10TX Pyrogallol Pyrogallic acid 10TX Pyronin B 10TX Pyronin Y 10TX Pyroxylin 15SS Pyrrole O8FL Pyrrole 2 carboxaldehyde 10TX Pyrrolidine O8FL Pyrrolidinone 1 methyl 2 O8FL Pyrrolidionecarbodithioic acid 1 ammonium salt 10TX Pyrrolidone 2 O8FL Pyruvaldehyde O8FL Pyruvate kinase 19N H Pyruvic acid 03CA 136 Explosion hazard H ighly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Quinacrine dihydrochloride hydrate 10TX Quinhydrone 10TX Quinine hydrobromide 10TX Quinine sulfate dihydrate 10TX Quinine sulfate monohydrate 10TX Quinine valeranate 10TX Quinoline O8FL Quinolinol 8 8 H ydroxyquinoline 10TX Raney nickel 09FS Raney nickel catalyst powder 09FS Red phosphorus amorphous 14WS Reinecke salt 14WS Resarzurin 10TX Reserpine 10TX Resmethrin 10TX Resorcinol 10TX Resorufin 10TX Retinol palmitate 10TX Rexyn 201 02CB Rhenium 11TX Rhodamine 10TX Rhodamine 6G 10TX Rhodamine B 10TX Rhodanine 10TX Rhodine 19N H Rhodinol O8FL Rhodium 11TX Rhodium chloride 11TX Rhodizonic acid dipotassium salt 10TX Rhonox 10TX
111. ide organophosphorus pesticide Bentazon Bentonite Benyl acetate Benz c acridine Benzal chloride Benzaldehyde Benzalkonium chloride Benzamide Benzanilide Benzanthracene 1 2 Benzenamine Benzene Benzene sulfonic acid Benzene sulfonyl chloride Benzenediol 1 3 Benzenediol 1 4 Benzenehexacarboxylic acid Benzenephosphonous acid phenyl phosponic acid Benzenesulfonamide Benzenetetracarboxylic acid 1 2 4 5 Benzenethiol thiophenol Benzenetricarboxylic acid hydrate 1 3 5 Benzenetricarboxylic acid 1 2 4 Benzethonium chloride Benzhydrol Benzidine Explosion hazard H ighly reactive May form unstable peroxides on standing CPC CODE 1ITX 170X 11TX 11TX 11TX 02CB 11TX 170X 11TX 11TX 170X 1ITX 11TX 11TX 11TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX 19NH 10TX 10TX 10TX 08FL 10TX 10TX 10TX 10TX 08FL 08FL 03CA 03CA 10TX 10TX 03CA 10TX 10TX 03CA 02CB 03CA 03CA 10TX 10TX 10TX 73 Appendix D UAB Waste Registry CHEMICAL NAME Benzidine dihydrochloride Benzidine hydrochloride Benzil Benzilic acid Benzimidazole Benzimide bis Benzo a pyrene Benzocaine Benzoic acid Benzoic acid 4 hydroxy 3 methoxy Benzoic acid sodium salt p hydroxymercuri Benzoic anhydride Benzoin Benzoin oxime alpha Benzonic acid Benzonitrile Benzophenone Benzopyrrole 2 3 Benzoquinone Benzothiazole Benzotrichloride Benzoyl alanine Benzoyl chloride Benzoyl peroxide
112. idine 2 2 amino 4 picoline Amino 4 methylpentane 2 Amino 4 nitrophenol 2 Amino 5 nitrophenol 2 Amino 6 bromobenzothiazole 2 Amino 6 mercaptopurine 2 Amino 6 methylpyridine 2 2 amino 6 picoline Amino 9 ethylcarbazole 3 ACE A minoacetophenone p Aminoacridine hydrochloride 9 Aminoacridine 9 Amino anthroquinone Aminoantipyrine 4 Aminoazotoluene o Aminobenzaldehyde Aminobenzene sulfonamide Aminobenzimidazole Aminobenzoic acid all isomers Aminobenzothiazole 2 68 Explosion hazard H ighly reactive May form unstable peroxides on standing CPC CODE 10TX 03CA 02CB 10TX 10TX 10TX 10TX 10TX 09FS 10TX 10TX 10TX 10TX 08FL 10TX 10TX 10TX 10TX 10TX 10TX 10TX 08FL 03CA 03CA 10TX 02CB 10TX 10TX 10TX 08FL 10TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX Appendix D UAB Waste Registry CHEMICAL NAME Aminobenzotrifluoride Aminobenzoyl glycine N 4 Aminobutyric acid 2 Aminobutyric acid 4 GABA Aminocaproic acid 6 Aminochrysene Aminocyclopentane carboxylic acid Aminoethanethiol hydrochloride Aminoethanol hydrochloride Ethanolamine HCl Aminoethanol 2 Aminoethyl pyridine Aminoethylamino ethanol 2 2 Aminoethylaminoethanol Aminoethylisothiouronium bromide 2 Aminoethyl piperidine Aminoguanidine bicarbonate Aminoguanidine sulfate Aminohippuric acid p Aminohomopiperidine N Aminoiso
113. in 19N H Tryptophan L 19N H TS 2 contains sodium hydroxide O8FL Tubocurarine chloride 10TX Tungsten 11TX Tungsten IV chloride 14WS Tungstic acid 11TX Tungstic oxide 11TX Turf fungicide 3336 10TX Turpentine O8FL Tween 20 10TX Tween 40 10TX Tween 80 sorbitan monooleate polyoxyethylene 10TX Tylosin 10TX Tylosin tartrate 10TX Tyramine hydrochloride 10TX Tyrosine 19N H Tyrothricin 19N H Undecenoic acid 10 10TX Undecylenic acid 10 Undecenoic acid 03CA Undecylenic aldehyde 10 Undecenal 08FL Unitol ACD tall oil 10TX Unitol DT tall oil 10TX Uracil 10TX Uracil mustard 10TX Uranine Fluorescein sodium salt 10TX Urea 19N H Urea nitrate wet 170X Urease 10TX Urethane O8FL Uric acid 10TX Uricase 10TX Uridine 5 triphosphate 19N H Uridine 5 diphosphate 19N H Uridylyl adenosine 19N H Valeraldehyde O8FL Valeric acid 03CA Valeric anhydride 03CA Valeronitrile 08FL Explosion hazard 151 Highly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Valeryl chloride 14WS Valine L 19NH Valproic acid 03CA Vanadium 11TX Vanadium pentoxide Vanadium V oxide 11TX Vancide 11TX Vanillic acid 4 H ydroxy 3 methoxybenzoic acid 03CA Vanillin 19NH Vanillomandelic acid VMA 10TX Vapam methyl carbamodithioic acid na salt 10TX Vectabond reagent 10TX Vegetable oil O8FL Veratrole 10TX Veren ol trisodium N hydroxy EDTA 10TX Versamin 900 03CA Versene 10TX Vi
114. in the laboratory or departmental office at all times All employees induding temporary employees must receive information and training on the following 5 3 1 The requirements of the Hazard Communication and Chemical Safety and Waste M anagement Programs 5 3 2 Locations where hazardous chemicals are present 5 3 3 The physical and health hazards of chemicals 5 34 How to read and interpret labels and MSDSs 5 35 Methods and observations used to detect the presence of hazardous chemicals 5 36 Thelocation and availability of the written program M SDSs the hazardous chemical inventory and any reference material 5 3 7 Methods of protection Employees must be informed and trained for hazards associated with any new chemicals introduced to the workplace Records of training must be kept by the departmental chemical hygiene officer or principal investigators and must include 5 5 1 The name and social security number of the person receiving training 55 2 Thelength and type of training 5 5 3 The date of training 25 6 ENVIRONMENTAL MONITORING 6 1 6 2 The UAB Department of Occupational Health and Safety will monitor employee exposure levels to any substance regulated by Occupational Safety and Health Administration OSHA or the American Conference of Governmental Industrial Hygienists ACGIH Results of this testing may be compared to OSHA Permissible Exposure Limits PELs ACGIH Threshold Limit Values TLVs NIOSH Recom
115. inc phosphide Zinc phosphite Zinc p phenolsulfonate Zinc salicylate Zinc stearate Zinc sulfate hexahydrate Zinc sulfide Zinc sulfite Zinc sulphocarbolate Zinc thiobenzoate Zinc granular Zirconium IV chloride Zirconium IV hydroxide Zirconium IV oxide Zirconium sulfate hydrate Explosion hazard H ighly reactive May form unstable peroxides on standing CPC CODE 10TX 08FL 10TX 10TX 08FL 08FL 19NH 10TX 170X 19NH 10TX 10TX 11TX 170X 11TX 11TX 11TX 11TX 03CA 11TX 1ITX 14WS 11TX 11TX 11TX 10TX 170X 11TX 11TX 170X 11TX 14WS 11TX 11TX 11TX 11TX 11TX 11TX 11TX 11TX 11TX 11TX 14WS 02CB 11TX 1ITX 153 Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE 154 Explosion hazard H ighly reactive May form unstable peroxides on standing sau propag pun eyng jo uorypota seinyryeu0S sAmmYpBry 10 speoz ogqnd aao THINE NopUNTRY jo eda eqs Surpredar uoeucagus sodandun urge ucedieunga T jo Jusunawdag ay pum manay OCU opem pun Gaag PUES AYA aui Jo muawasmbas aqwonddw o Surpaeoow worden 3o wonpuoo edid uy aux pue pajaqu pi pagasa posed poquisap pogieee s Apodoud amv prias ponte sac aq wap 4jrizo or st sti WIFE FiTHAA ey paa zn gi xoq pay ANANAOYNVN STVIHAIVN SHOGUVZVH NYHONINAIG LY VNVEVIY 40 ALISUHAINN p uiu Page of UNIVERSITY OF ALABAMA AT BIRMINGHAM HAZARDOUS MATERIALS MANAGEMENT CHEMICAL WASTE MANIFEST Packing Inst
116. investigators on matters relating to laboratory safety appropriate storage and handling of chemicals and their proper disposal excluding radioactive materials 2 1 3 Aiding investigators in the development of appropriate emergency procedures for dealing with accidental spills and containment of non radioactive chemicals 2 14 Surveying laboratories in which hazardous chemicals are used particularly in large quantities or those of unusual hazard potential to ensure compliance with prescribed safety guidelines or governmental regulations 2 15 Investigating accidents or incidents involving hazardous chemicals excluding radionuclides to determine probable cause and any violation of safety guidelines or breach of containment Upon completing the investigation the Chemical Safety Director will prepare a written report of findings for review and action if any by the UAB Chemical Safety Subcommittee 2 1 6 Coordinating the UAB Hazard Communication and Chemical Safety and Waste Management Programs The Chemical Safety Director upon concurrence by the chairperson of the UAB Chemical Safety Subcommittee or in his her absence by at least three other technically qualified members of the Committee may stop any work involving the use of hazardous chemicals that creates an indisputable risk or danger to personnel or involves experiments prohibited by the Institution The entire Committee then will review the problem and forward written 2
117. ir bubbles from syringes and IV tubing injecting drugs disconnecting IV tubing fixing leaking tubing or syringe connections disposing of contaminated material withdrawing drug from a vial ec Indirect Exposure is defined as contact with a hazardous drug through blood and body fluids Proper equipment and technique must be utilized to protect 181 B 182 Appendix M Safe Handling of Hazardous Drugs personnel and prevent contamination of the work environment with hazardous drugs Personnel involved in the preparation or handling of hazardous drugs are hereby encouraged to consult their personal physician regarding their own potential health risks due to genetic factors health status or other personal situations Personnel working with hazardous drugs who are pregnant or planning pregnancy should inform their supervisor and seek guidance from their personal physician as to whether they should be assigned duties which do not involve administering or handling these agents Based on available evidence it is reasonable to assume that proper technique and use of personal protective equipment should minimize the risk to the health care worker SAFETY PRECAUTIONS Personnel Practices Preparation D ispensation 1 All doses of hazardous drugs should be prepared in the pharmacy under a biological safety cabinet and delivered to the nursing unit 2 Hazardous drugs that are subject to spillage or contamination should be delivere
118. ity in many technical and diagnostic procedures When contained properly it is of little threat to our health Immediate attention to mercury spills is important because spilled mercury can accumulate over time resulting in exposure to mercury vapor 9 4 1 When a spill occurs the following steps should be performed 9 4 1 1 Restrict the area allow no one to enter the room except for urgent treatment of a patient or containment of the spill 9 4 2 9 4 12 Contact the Hazardous Materials Manager 4 3797 in the Department of Occupational Health and Safety The department is equipped with a special mercury vacuum to effectively remove spilled mercury 9 4 1 3 Patients may need to be moved to allow mercury to be cleaned from the area Broken thermometers that contain small amounts of mercury may be safely collected in a container that can be sealed Always wear disposable gloves when cleaning up mercury and dispose of all mercury and mercury contaminated waste through the chemical waste program Anyone handling mercury or cleaning up mercury spills should wash their hands thoroughly with soap and water when finished Report all mercury spills to the Hazardous Materials M anager 39 10 EMERGENCY PROCEDURES 10 1 10 2 10 3 10 4 10 5 10 6 10 7 10 8 10 9 When an emergency occurs in a non Hospital area report the nature and location of the emergency to UAB Police 4 3535 Hospital locations dial 4 0001 Gi
119. k of concentration and eye nose and throat irritation Generally an indoor air quality screen is initiated when 20 or more of the employees in an area are affected Usually these screens are collaborative efforts involving both the Chemical Safety Division and the Biosafety Division Investigations of indoor air quality IAQ often fail to identify any harmful levels of specific toxic substances Employee complaints may result from items such as cigarette smoke odors low level contaminants poor air circulation thermal gradients humidity job pressures lighting workstation design or noise The combined effect of multiple low level air contaminants has not been investigated thoroughly and may be a cause of the problem 6 3 1 Recommended Ventilation Rates The American Society of Heating Refrigerating and Air Conditioning Engineers ASH RAE established recommended ventilation rates for indoor environments in 1973 6 3 1 1 ASHRAE amended this standard in 1975 to specify the minimum value of 5 cubic feet per minute CFM of outdoor air per person be used in building design This standard has been incorporated into the building codes of many cities and states 6 3 12 The62 1989 standard recommends a minimum of 15 CFM of outdoor air per person for offices reception areas and 20 CFM per person for general office space with a moderate amount of smoking Sixty CFM per person is recommended for smoking lounges with local mechanical
120. late Ethyl phenylacetate Ethyl phthalate Ethyl propionate Ethyl pyridine 2 Ethyl quinolinium iodide 1 Ethyl stearate Ethyl thiocyanate Ethyl trichloroacetate Ethyl urea Ethyl vinyl ether Ethyl 1 butanol 2 2 Ethylbutyl alcohol Ethyl 1 hexanol 2 Ethyl 2 bromopropionate Ethyl 2 methyl pyridine 5 Ethyl 2 pentene 3 Ethyl 3 3 dimethylamino propyl carbodimide 1 Ethyl 3 3 dimethylaminopropyl carbodiimide 1 Ethylamine hydrochloride Ethylamine anhydrous gas Ethylamine aqueous sulution Ethylaniline N Ethylbenzene 102 Explosion hazard H ighly reactive May form unstable peroxides on standing CPC CODE 10TX 08FL 10TX 14WS 10TX 10TX 1555 10TX 08FL 08FL 08FL 09FS 08FL 14WS 08FL 08FL 10TX 08FL 02CB 08FL 08FL 08FL 10TX 10TX 08FL 08FL 08FL 08FL 08FL 10TX 10TX 08FL 08FL 10TX 08FL 08FL 08FL 08FL 02CB 08FL 10TX 10TX 10TX 07CG 08FL 08FL 08FL Appendix D UAB Waste Registry CHEMICAL NAME Ethyldisulfide Ethylene bis oxyethylenenitrilotetra acetic acid Ethylene carbonate Ethylene diacetate Ethylene diacrylate Ethylene dibromide Ethylene dichloride Ethylene dimethacrylate Ethylene glycol Ethylene glycol diacetate Ethylene glycol dimethylacrylate Ethylene glycol monomethyl ether Ethylene glycol monomethyl ether acetate Ethylene maleic anhydride copolymer Ethylene oxide Ethylene sulfide Ethylenediamine Ethylenediamine dihydrochloride E
121. licate Aluminum sodium sulfate Aluminum stearate Aluminum sulfate Aluminum sulfide Aluminum metallic powder Aluminum metallic sticks Amaze 6 isofenphos or oftanol Explosion hazard H ighly reactive May form unstable peroxides on standing CPC CODE 10TX 10TX 10TX 10TX 10TX 10TX 19NH 10TX 10TX 10TX 10TX 08FL 08FL 08FL 08FL 10TX 08FL 08FL 10TX 10TX 14WS 15SS 10TX 10TX 11TX 19NH 19N H 10TX 02CB 14WS 170X 11TX 03CA 02CB 1ITX 14WS 11TX 14WS 11TX 11TX 10TX 11TX 02CB 14WS 11TX 10TX 67 Appendix D UAB Waste Registry CHEMICAL NAME Amberlite Amberlite acidic Amberlite basic Amberlite IRA 68 Amine 2 4 D Amino anthracene 1 Amino anthracene 2 Amino naphthol hydrochloride Amino tetrazole Amino thiazole 2 Amino 1 2 4 triazole 3 Amino 1 naphthalenesulfonic acid 4 Amino 1 naphthol 3 6 disulfonic acid 8 Amino 1 propanol 3 propanolamine Amino 2 hydroxymethyl 1 3 propane 2 Amino 2 hydroxymethyl 1 3 propanediol 2 Amino 2 3 dihydro 1 4 phthalazinedione 5 Amino 2 4 7 pteridinediol Amino 2 hydroxymethyl 1 3 propanediol 2 Amino 2 methyl 1 3 propandiol 2 Amino 2 methyl 1 propanol 2 Amino 2 methylpropanol Amino 2 naphthol sulfonic acid 5 Amino 2 naphthol 4 sulfonic acid 1 Amino 2 propanol 1 Amino 3 methyl pyridine 2 2 amino 3 picoline Amino 4 2 1 3 benzothiazole Amino 4 chlorophenol 2 p chloro o aminophenol Amino 4 methyl pyr
122. loro 3 6 dihydroxy p benzoquinone 2 5 10TX Dichloro 4 iodobenzene 1 2 10TX Dichloro 4 nitrophenol 2 6 10TX Dichloro 5 6 dicyano 1 4 benzoquinone 2 3 10TX Dichloro 5 nitropyridine 2 6 10TX Dichloro 6 nitrophenol 2 4 10TX Dichloroacetic acid 03CA Dichloroaniline 2 5 10TX Dichlorobenzamide 2 4 10TX Dichlorobenzene all isomers 08FL Dichlorobenzenethiol 10TX Dichlorobenzidine 3 3 10TX Dichlorobenzoyl peroxide 2 4 1555 Dichlorobenzyl alcohol 2 4 10TX Dichlorobutane 1 4 08FL Dichlorodifl uoromethane 07CG Dichlorodimethyl silane 14WS Dichlorodimethylsilane dimethyldichlorosilane 14WS Dichlorodiphenylmethane 03CA Dichloroethane O8FL Dichloroethane 1 1 O8FL Explosion hazard 91 Highly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME Dichloroethane 1 2 Dichloroethylene 1 1 Dichloroethylene 1 2 cis Dichloroethylene 1 2 trans Dichlorofluorescein 2 7 Dichlorohexane 1 6 Dichloroindole Dichloroindophenol 2 6 Dichloroisoproterenol Dichloroisoproterenol hydrochloride Dichloromethane Dichloromethyl benzene Dichloromethylmethyl ether alpha alpha Dichloromethylsilane Dichloromide Dichloronaphthoquinone 2 3 Dichloro o anisic acid 3 6 Dichlorophenol 2 4 Dichlorophenol 2 6 Dichlorophenoxyacetic acid 2 4 Dichlorophenoxyacetic acid 2 4 N H4 salt Dichlorophenyl phosphine Dichlorophenyl 2 isopropylaminoethanol 1 3 4 Dic
123. losion hazard 121 H ighly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME Methylparaben Methylphenarsazine Methylphenazonium methosulfate N Methylpiperidine 1 Methyl p nitroaniline N Methyl p toluenesulfonate Methylpyrazine 2 Methylpyridine 4 Methylpyrrolidine N Methylsuccinic acid Methylthiobutanoate Methylthio m cresol 4 Methylthiophenol 4 Methyltrioctylammonium chloride Methylumbelliferone 4 Methylurea Methylvaleraldehyde 3 Metribuzin Metrizamide Mild silver protein Millipore activator solution contains acetonitrile 1 h tetrazole Millipore amidite diluent contains acetonitrile Millipore CAP B solution contains tetrahydrofuran pyridine 1 methylimidazole Millipore oxidizer solution contains iodine pyridine tetrahydrofuran Millipore TBPA CAP A solution t butyl phenoxyacetic anhydride tetrahydrofuran Mineral oil Mineral spirits Mithramycin Mitomycin C MN cellulose powder Molybdenum Molybdenum trioxide Molybdic acid Monacetin Monochloroacetic acid Monomethylamino phenol sulfate p Monothioglycerol Mordant orange Morin hydrate Morpholine Morpholineethanesulfonic acid hydrate 4 MES Mossy tin MTT MTT waste contains 3 4 5 dimethylthiazole 2 yl 2 amp 5 diphenyl 2H tetrazolium bromide 122 Explosion hazard H ighly reactive May form unstable peroxides on standing CPC CODE 10TX
124. manual to describe the operation of the Chemical Safety Program and to provide guidance in establishing safe work practices for the use of chemicals This program applies to all work operations at this University where employees may be exposed to hazardous substances under normal working conditions or during an emergency The Chemical Safety and Waste Management Manual combines both the Chemical Hygiene Plan for laboratories and the Hazard Communication Program for maintenance environmental services and other support personnel The Occupational Safety and Health Administration OSHA Hazard Communication Standard may be found at http www osha sic gov O shStd data 1910 1200 html The policies and procedures outlined herein are considered the standard of care for chemical safety and environmental health and have been adopted as official University Policy 2 RESPONSIBILITIES 2 1 Chemical Safety Director The Chemical Safety Director is a member of the Department of Occupational Health amp Safety staff and is primarily responsible for the implementation of the UAB Chemical Safety and Waste Management Program in all areas on UAB premises Major duties or activities include the following 2 1 1 Assisting in the preparation and periodic updating of the UAB Chemical Safety and Waste Managenent Manual which is in accordance with University policy and consistent with governmental regulatory statutes 2 1 2 Providing consultation to
125. mended Exposure Limits RELs or other applicable guidelines Routine M onitoring Routine monitoring may be initiated under several conditions if there is reason to believe exposure levels exceed the designated action level usually one half the PEL if a regulatory agency mandates regular monitoring or if a change in a procedure may significantly change employee exposure to a substance 6 1 1 If the action level is exceeded corrective procedures will be recommended and monitoring will be repeated periodically as required by the standard 6 1 2 If the action level is not exceeded on either the initial or follow up monitoring then monitoring may be discontinued as allowed by the standard 6 1 3 Certain chemical agents are monitored on a scheduled basis If your area uses one of these agents on a regular basis and is not scheduled for routine monitoring please contact the Chemical Safety Division These include Halogenated anesthetics halothane ethrane isoflurane desflurane semi annually in surgical suites as requested in other areas e Nitrous oxide semi annually in surgical suites as requested in other areas e Glutaraldehyde Cidex annually e Ethylene oxide annually e Xylene annually e Formaldehyde annually Acceptable Exposure Limits The following is a list of acceptable exposure limits to those environmental contaminants most commonly measured Limits are based on an 8 hour per day
126. n in a coat blanket or whatever is available to extinguish the fire Roll the person on the floor if necessary Remove any clothing contaminated with chemicals Douse with water to remove heat Wrap the injured person to avoid shock and exposure Get medical attention Do not touch a person in contact with a live electrical circuit Disconnect the power first or you may be seriously injured 41 11 CHEMICAL WASTE MANAGEMENT 111 Overview 11 2 Used or unwanted chemicals generated at UAB can be disposed of by the following methods 11 1 1 If the chemicals are non hazardous they may be disposed of through the regular trash as non hazardous chemical waste Contact the Hazardous and Regulated M aterials Manager 4 3797 for assistance 11 1 2 If the materials are hazardous there are three disposal options 11 1 2 1 Disposal through a special packing labeling and handling system designed for laboratory type chemicals or chemicals used by the maintenance staff 11 1 2 2 Disposal through the yellow waste barrel system designed for items requiring incineration This would include materials such as animal bedding paper etc contaminated with trace amounts of carcinogens or reproductive toxins highly toxic material or material of unknown toxicity not regulated as EPA hazardous waste 11 1 2 3 Disposal through the hazardous drug chemotherapy disposal containers This would include IV tubing and other items associated with th
127. nate Ammonium cerium IV sulfate Ammonium chloride Ammonium chromate Ammonium citrate dibasic Ammonium dichromate Ammonium ferricyanide Ammonium fluoride Ammonium formate Ammonium hydrogen fluoride solid Ammonium hydroxide Ammonium iodide Ammonium metavanadate Ammonium molybdate Ammonium nitrate Ammonium oxalate Ammonium peroxydisulfate Ammonium persulfate Ammonium phosphate dibasic Ammonium phosphate monobasic Ammonium picrate Ammonium potassium tartrate Ammonium purpurate Ammonium pyrrolidine dithiocarbamate Ammonium salicylate Ammonium sulfamate Ammonium sulfate Ammonium sulfide Ammonium sulfite Ammonium tartrate Ammonium thiocyanate Ammonium thiosulfate Ammonium valerate Ammonium vanadate A mmonium 1 pyrrolidine carbodithionate Amobarbitol sodium 70 Explosion hazard H ighly reactive May form unstable peroxides on standing CPC CODE 10TX 08FL 10TX 07CG 10TX 10TX 11TX 03CA 11TX 11TX 19NH 19NH 11TX 11TX 170X 19N H 170X 11TX 11TX 10TX 03CA 02CB 11TX 11TX 11TX 1555 10TX 1555 1555 19NH 19NH 10TX 10TX 10TX 10TX 10TX 11TX 19N H 08FL 02CB 10TX 10TX 10TX 10TX 11TX 10TX 10TX Appendix D UAB Waste Registry CHEMICAL NAME Amphetamine sulfate Amsonic acid Amyl acetate Amyl alcohol Amyl alcohol tert Amyl butyrate N Amyl chloride N Amyl iodide 1 Idopentane or N amyl iodide A myl nitrate Amylamine N Amylopectin Amylphenol o sec Amylphenol p ter
128. nces if there is a utility service failure such as loss of cooling water when no one is present 3 1 12 Use of Hoods Use the hood for operations that might result in the release of toxic chemical vapors gases or dusts 3 1 12 1 Have hoods certified annually to ensure adequate performance It is recommended that this be conducted through the Department of Occupational Health and Safety Division of Biosafety since current performance and certification files are maintained in the office 3 1 12 2 Minimize the amount of material in the hood Do not block vents or obstruct airflow 3 1 12 3 Use only a perchloric acid hood with a properly functioning wash down system when working with perchloric acid of greater than 70 concentration 3 1 12 4 Do not use hoods for chemical storage 3 1 13 Emergency Eyewash and Shower Equipment Every laboratory that uses materials that are irritating to the eyes must have an eyewash fountain located within that laboratory unit Generally one eyewash is required per laboratory unit however laboratories considered high hazard areas might require additional eyewash units Contact maintenance for information regarding purchase and installation of eyewashes or safety showers 3 1 13 1 American National Standard for emergency eyewash and shower equipment ANSI Z358 1 1990 has been adopted by the University of Alabama at Birmingham Department of Occupational Health and Safety as the single criteri
129. ne glove will provide the protection and the surgeons glove will provide the tactility 3 Make certain that hands are clean before using gloves If chemicals have inadvertently contaminated the skin prior to using the glove the glove will soeed up the process of skin penetration 4 Try to select the type of glove polymer that is best suited for your particular application Often the MSDS will suggest a glove type for use with a particular chemical If you have questions consult with the Department of Occupational H ealth and Safety 5 f the above guidelines are followed and gloves are changed frequently particularly when liquid comes in contact with the glove then any of the thin rubber gloves available on the market should serve well for general laboratory purposes 159 Appendix G Protective Gloves TABLE 1 Resistance to Chemicals of Common Glove M aterials E Excellent G Good F Fair P Poor Chemical Natural Neoprene Nitrile Vinyl Rubber Acetaldehyde G G E G Acetic Acid E E E E Acetone G G G F Acrylonitrile P G n a F Ammonium hydroxide G E E E Aniline F G E G Benzaldehyde F F E G Benzene P F G F Benzyl chloride F P G P Bromine G G n a G Butane P E n a P Butyraldehyde P G n a G Calcium hypochlorite P G G G Carbon disulfide P P G F Carbon tetrachloride P F G F Chlorine G G n a G Chloroacetone F E n a P Chloroform P F G P Chromic acid P F F E Cyclohexane F E n a P Dibenzyl ether F G n a P Dibutyl phthalat
130. ng Leave a 10 headspace when filling chemical waste collection containers 11 5 1 2 Shock Sensitive and Water Reactive Compounds and Lecture Bottles Shock sensitive and water reactive compounds and lecture bottles require special handling These compounds are listed in Appendix B of this manual When dealing with these compounds call the Hazardous Materials Facility 43797 for special instructions These materials should always be packed separately from other chemicals 11 5 1 3 Packing Filled Containers in Boxes Chemicals that have the potential to react with each other should not be packed in the same box 11 5 1 3 1 Determine the packing hazard class for each chemical waste Classes are listed in Appendix C When determining the class for a mixture of chemicals reactivity has priority over toxicity If you have difficulty determining the packing class of a mixture call the Hazardous Materials M anager 4 3797 11 5 1 3 2 Segregate the wastes according to the hazard class and pack them into cardboard boxes Do not pack different classes in the same box Place dividers and shock absorbing materials vermiculite in between the containers 11 5 1 3 3 When packing dry chemicals the total weight should not exceed 50 Ibs 22 Kg When packing 4L bottles no more than four 4 glass bottles or six 6 plastic bottles should be placed in a box 11 5 1 3 4 Boxes must be large enough to completely close over the tops of
131. ng container and any incoming containers are properly labeled The label must provide the following information Theidentity of the chemical Any warnings The manufacturer s name and address Products that are not labeled should be considered hazardous until identification and hazard evaluation can be completed Temporary or transfer containers intended for immediate use by the person who transferred the chemical need not be labeled However if the chemical is left unattended even 19 20 4 6 4 5 4 4 5 6 briefly or is to be used by another individual the container must be labeled Temporary labels must include The identity of the chemical Any warnings The target organs affected if applicable Signs are used to warn employees of chemical and physical dangers such as designated areas where carcinogens or highly toxic chemicals are used or stored Chemical hygiene officers should post all high hazard areas or hazardous chemical storage areas with the proper signs Emergency phone numbers and emergency contact numbers should be posted on all laboratory doors The contact for laboratories should be the principal investigator or chemical hygiene officer Emergency notification stickers are available from the Department of Occupational H ealth and Safety Certain accrediting agencies require additional information Record Keeping 4 6 1 4 6 2 4 6 3 4 6 4 4 6 5 Records will be generated and retained a
132. nicillamine D Penicillin G Pentacarbonyl iron Pentachlorobenzene Pentachloroethane Pentachloronitrobenzene Pentachlorophenol Pentadecane Pentadecanoic acid Pentadecylresorcinol 5 N Pentadiene 1 3 Pentadione 2 4 Pentafluorophenol 128 Explosion hazard H ighly reactive May form unstable peroxides on standing CPC CODE 11TX 03CA 08FL 10TX 03CA 14WS 10TX 10TX 10TX 10TX 170X 08FL 10TX 11TX 1ITX 11TX 10TX 19NH 10TX 19NH 08FL 19NH 08FL 09FS 10TX 10TX 08FL 170X 10TX 10TX 10TX 11TX 11TX 03CA 10TX 10TX 08FL 10TX 10TX 10TX 10TX 08FL 10TX 10TX 08FL 08FL 10TX Appendix D UAB Waste Registry CHEMICAL NAME Pentamethylbenzene Pentamethylene bromide Bromopentane Pentamethylene glycol 1 5 Pentanediol Pentamethylene iodide Pentane Pentanedione 2 3 Pentanedione 2 4 Acetylacetone Pentanesulfonic acid sodium salt Pentanol Pentanone 2 Pentanone 3 Pentene 1 Pentene cis 2 Pentylamine N Pepsin Peracetic acid 40 Peracetic acid solution Perchloric acid Perchloroethylene Periodic acid Permount contains xylene Permutit Perthane Petroleum ether Petroleum spirits Phallodin Phalloidin Phellandrene alpha Phenacetin Phenanthrene Phenanthroline monohydrate 1 10 Phenanthroline 1 10 Phenazine methosulfate Phenethyl alcohol Phenethyl isothiocyanate Phenethylamine alpha Phenol Phenol acid Phenol reagent solution Phenol red
133. nsussssnsnsunnnnnensusnnnsensnensnssnensnsenensenenenn 17 4 1 CHEMICAL HYGIENE PLAN ccccsrsccsesessceccssscccscsccescssessnersnsesccesssssessssssssecessoess 17 4 2 PROCUREMENT sesccosscssossssnnsesnnnnuunnnunnsnnnnnnnnsnnnnnennnnsnnnnnssnnsennnsnnnunsnssunsssnnnsnnnens 17 4 3 CHEMICAL INVENTORY ccsccssscsessssssscscccsccsncesersccssensnnresssssssssssensssssasossoessoss 18 44 MATERIAL SAFETY DATA SHEETS MSDS erret 18 4 5 LABELS AND SIGNS 00s0000000ss000s00ns000000n000000020002000008000002000000000000020000000 10001000 19 4 6 RECORD KEEPING 20s000 000s000u000s000200000002220n20002000000000000020000000000000000n0000100010000 20 4 7 CHEMICAL STORAGE eerte e tent tnttn tense tn otto sensns snas setas a senatus eua 21 48 TRANSPORTATION eene enn tentent tentent nostras en aser nostras erase on seen seen sena annt 22 5 TRAINING sssssersenssssnssnensssenssnensenensenessensenenssnsnsensssssssssnsnssnsnsssnsnunnensnnensenensensenee 25 6 ENVIRONMENTAL MONITORING uusussssssnsnssssnsnsnsnnsnnennnnnnennnenennnnenensnnensene 27 6 1 ROUTINE MONITORING enn 27 6 2 ACCEPTABLE EXPOSURE LIMITS 2 20200200200400400002202000220000000000000000100000 27 6 3 INDOOR AIR QUALITY PROBLEMS ee eres e enero eene neenon sensns tanen ann 28 6 3 1 Recommended Ventilation Rates e
134. nyl acetate 08FL Vinyl chloride 07CG Vinyl ethyl ether inhibited O8FL Vinyl sulfone O8FL Vinyl 1 cyclohexene 4 O8FL Vinyl 2 pyrrolidone N 08FL Vinylacetic acid 03CA Vinylcydohexene dioxide 10TX Vinylferrocene 11TX Vinylidene chloride inhibited O8FL Vinylimidazole 1 O8FL Vinylpyridine 2 O8FL Vinylpyridine 4 monomer 02CB Vinylpyridine 2 poly O8FL Vinylpyridine 4 O8FL Visnagin 10TX Vitamin A all trans Retinol 19N H Vitamin B6 Pyridoxine 19NH VitaminD2 Ergocalciferol 19NH Vitamin K3 19NH Vondozeb 11TX Warfarin 10TX Water 19N H Wright s stain 10TX Xanthen 9 ol 9 hydroxyxanthene 10TX Xanthene 9 carboxylic acid 03CA Xanthine oxidase 19NH Xanthone 9 Xanthenone 10TX Xanthydrol 9 Hydroxyxanthene 10TX X ray film developer 02CB Xylene cyanole 10TX 152 Explosion hazard Highly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME Xylene sulfonate Xylene all isomers Xylenol orange sodium salt Xylenol 4 chloro 3 5 Xylidine 2 4 Xylol xylene mixture Xylose Yohimbine Zenker s solution Zeolite Zephiran Zerlate Zinc Zinc Il nitrate hydrate Zinc acetate dihydrate Zinc amalgam Zinc bromide Zinc carbonate Zinc chloride Zinc chloride solid Zinc cyanide Zinc dust Zinc iodide Zinc lactate Zinc metal Zinc naphthenate Zinc nitrate hexahydrate Zinc orthosilicate Zinc oxide Zinc perchlorate hexahydrate Zinc phosphate Z
135. ochloride p aminodimethylaniline Dimethylpentane 2 3 Dimethylphenethylamine alpha alpha Dimethylphenol all isomers Dimethyl p nitrosoaniline Dimethyl p nitrosoaniline N N N nitrosodimethylaniline Dimethylpolysiloxane Dimethyl p phenylazo aniline N N DAB Dimethyl p phenylenediamine p aminodimethylaniline Dimethyl p phenylenediamine sulfate N N Dimethyl p phenylenediamine N N Dimethyl p phenylenediamine N N hydrochloride Dimethyl p toluidine N N Dimethylpyridine 2 4 2 4 lutidine Dimethylquinoline 2 6 Dimethylsuberimidate Dimethylsuberimidate hydrochloride Dimethylsuccinic acid meso 2 3 Explosion hazard Highly reactive May form unstable peroxides on standing CPC CODE 10TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX 1555 02CB 10TX 02CB 14WS 03CA O8FL 14WS 10TX 08FL 08FL 08FL 10TX 08FL 10TX 11TX 10TX 08FL 10TX 08FL 08FL 10TX 10TX 08FL 08FL 10TX 10TX 10TX 10TX 10TX 08FL 08FL 10TX 10TX 10TX 10TX 97 Appendix D UAB Waste Registry CHEMICAL NAME Dimethylsulfate methyl sulfate Dimethylsulfolane 2 4 Dimethylthiocarbamoyl chloride Dimite dimethyl carbinol Di N heptylamine Dinitramine Dinitrilodiphenol Dinitroaniline 2 4 Dinitroanisole 2 4 Dinitrobenzene all isomers Dinitrobenzenesulfenyl chloride 2 4 Dinitrobenzoic acid 3 5 Dinitrobenzoyl chloride 3 5 Dinitrofluorobenzene 2 4 Dinitro o cresol 4 6 Dinitro
136. odium silicate solution Sodium silicofluoride Explosion hazard H ighly reactive May form unstable peroxides on standing CPC CODE 170X 02CB 10TX 14WS 14WS 1ITX 1ITX 02CB 170X 03CA 170X 11TX 11TX 10TX 10TX 10TX 10TX 170X 1555 170X 170X 14WS 170X 170X 10TX 10TX 19NH 19NH 19NH 02CB 1555 1555 10TX 19NH 10TX 10TX 11TX 03CA 10TX 10TX 10TX 10TX 11TX 11TX 19NH 02CB 11TX 141 Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Sodium stannate trihydrate 11TX Sodium stearate 19N H Sodium succinate 19N H Sodium sulfate 11TX Sodium sulfide nonahydrate 02CB Sodium sulfite 11TX Sodium tartrate Tartaric acid sodium salt 19N H Sodium TCA sodium trichloroacetate 10TX Sodium tetraborate 19N H Sodium tetraphenylborate 10TX Sodium tetrathionate 10TX Sodium thiocyanate 11TX Sodium thioglycolate M ercaptoacetic acid Na salt 10TX Sodium thiosulfate 11TX Sodium titanate 11TX Sodium trimetaphosphate 19N H Sodium tungstate dihydrate 11TX Sodium B naphthoquinone 4 sulfate 10TX Solvent blue 38 Luxol fast blue M BSN 10TX Sopropyltoluene p O8FL Sorbic acid 2 4 H exadienoic 10TX Sorbitol D 19N H Sorbose L 19N H Soybean trypsin inhibitor 19N H Spermine 02CB Squalene O8FL Stannic IV chloride anhydrous 14WS Stannic IV chloride hydrated 03CA Stannic IV oxide 11TX Stannous II sulfide 11TX Stannous chloride Tin chloride 11TX Stannous oxalate 11TX Stannous sulfate
137. ol OSFL Isobutyl chlorocarbonate 14ws Isobutyl chloroformate 14ws Isobutyl formate 08FL Isobutyl vinyl ether O8FL Isobutylamine O8FL Isobutyl benzene O8FL Isobutyric acid 03CA Isocitric dehydrogenase 19NH Isoeugenol 10TX Isoleucine 19N H Isoniazid 10TX Isonicotinic acid 10TX Isonicotinic hydrazide 10TX Isooctane O8FL Isoorotic acid 10TX Isopentyl alcohol O8FL Isopentyl hexanoate 10TX Isopentyl salicylate 10TX Isophorone 08FL Isophthalaldehyde 10TX 112 Explosion hazard Highly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Isophthalic acid 10TX Isophthaloyl chloride 14WS Isoprene 08FL Isopropanol 08FL Isopropenyl acetate 08FL Isopropoxyphenyl N methylcarbamate o 10TX Isopropyl acetate O8FL Isopropyl acetone O8FL Isopropyl alcohol O8FL Isopropyl carbanilate 10TX Isopropyl ether 15SS Isopropyl nitrate O8FL Isopropyl sulfide O8FL Isopropylamine 08FL Isopropylamino 3 1 naphthoxy 2 propanol H CI 1 10TX Isopropylaniline p 08FL Isopropylbenzaldehyde p O8FL Isopropylcyclohexylamine N O8FL Isopropyl N 3 chlorophenyl carbamate 10TX Isoproterenol 10TX Isoproterenol hydrochloride 10TX Isoquinoline 10TX Isosafrole 10TX Isovaleraldehyde O8FL Isovaleric acid 03CA Isovalerylglycine 10TX Itaconic acid 10TX Kaolin 19N H Kasil MR 40 contains potassium silicate 11TX Kelthane 10TX Kepone 10TX Keratin 19N H Kerosene O8FL Ketamine hydrochloride 10
138. olychlorinated biphenyls 2 3 7 8 Tetrachlorodibenzo p dioxin Thorium dioxide Vinyl chloride 3 2 1 Personal Protection Use all reasonable precautions to minimize exposure Avoid inhalation ingestion and skin contact Wear a disposable protective outer garment lint free and impervious such as a closed front type gown with long sleeves and knit cuffs Cuffs must be tucked under gloves Wear appropriate gloves long sleeves and protective eyewear Shorts and short skirts do not provide adequate protection from these agents and should not be worn Wash hands before and after working with these materials 3 2 2 Work and Storage Areas The above substances must be used and stored in areas with restricted access Special warning signs must be posted in these areas Containers should be stored in chemically resistant trays and work must be performed within or above such trays Cover surfaces where these substances are used with absorbent plastic backed paper Performance certified hoods or other containment devices must be used when generation of toxic vapor gases dusts or aerosols may occur 3 23 Records Maintain an inventory of amounts of these materials in the lab the workers involved any special training conducted and any emergency information Material Safety Data Sheets for these substances should be kept readily accessible in the designated work area 3 2 4 Working Alone Assure that at least two people are present at all
139. om a different polymer starting material and consequently has different abilities to protect against exposure to chemicals Four major types of laboratory gloves are listed in Table 1 along with their relative protection against selected chemicals These gloves are generally available from most laboratory supply houses It should be noted that even when the above gloves are used for the appropriate classes of chemicals the amount of protection that is provided is extremely variable The vapor form of the liquid chemical will break through to the skin side of the glove in most cases within a matter of minutes While for most chemicals this vapor exposure will not be particularly harmful for some of the more toxic chemicals the exposure can be harmful In addition once chemicals reach the skin the glove acts as a barrier that aids in the penetration of the chemicals through the skin Effectively a process called occlusion can occur by which the chemical penetrates the skin more easily when trapped between the glove and the Skin than if the skin were exposed without a glove From this the following guidelines for the use of gloves are necessary 1 Change gloves frequently particularly if they become wet with the chemical 2 For particularly toxic compounds especially those that are polar a polyethylene glove may be used In order to improve coordination apply a natural rubber surgeons glove over the polyethylene glove The polyethyle
140. omercuri phenol p Chloromercuribenzoic acid 4 Chloromercuribenzoic acid sodium salt 4 Chloromercuric benzoate p Chloromercuric benzoic acid p Chloromercuricphenylsulfonate p Chloromethyl methyl ether Chloromethylbutane Chloromethylpropane isobutyl chloride Chloromycetin Chloronaphthalene 1 Chloronaphthalene 2 Chloronitrobenzene all isomers Chloronitroethane 1 1 Chloro o toluidine hydrochloride 4 Explosion hazard Highly reactive May form unstable peroxides on standing CPC CODE 14WS 10TX 10TX 08FL 10TX 08FL 03CA 08FL 10TX 10TX 10TX 10TX 10TX 10TX 08FL 14WS 08FL 08FL 10TX 08FL 10TX 03CA 14WS 08FL 08FL 08FL 11TX 10TX 08FL 10TX 10TX 10TX LITX 11TX 11TX 10TX 10TX 11TX O8FL O8FL 08FL 10TX 10TX 10TX 10TX 10TX 10TX 83 Appendix D UAB Waste Registry CHEMICAL NAME Chloro o tolyloxy acetic acid 4 Chloroperoxybenzoic acid meta Chlorophenarsazine 10 Chlorophenol all isomers Chlorophenoxyacetic acid Chlorophenyl isocyanate p Chlorophenyl 2 thiourea 1 2 Chlorophenyl N N dimethylurea N p Chlorophenylhydrazine hydrochloride Chlorophyll Chloropicrin liquid Chloroplatinic acid Chloro p nitrotoluene alpha Chloro p phenylacetophenone 2 Chloropropane 2 Chloropropionaldehyde diethyl acetal beta Chloropropionic acid beta Chloropropionitrile Chloropropionyl chloride Chloropropiophenone 3 Chlorosalicylaldehyde 5 Chlorosalicylic acid
141. on are properly trained about the potential hazards of the chemicals they use in their work area and trained in the proper use of equipment needed to safely handle these materials The department chairperson is responsible for appointing a chemical hygiene officer who will ensure compliance with the Chemical Safety Program and serve as a contact with our office Principal Investigator Supervisor The principal investigator or supervisor is responsible for the following 2 4 2 3 1 2 3 2 2 3 3 2 3 4 2 3 5 2 3 6 2 3 7 2 3 8 Complying with the UAB Chemical Safety and Waste Management M anual and all applicable regulations Ensuring that all persons directly involved in using hazardous chemicals are thoroughly trained in methods to minimize exposure and understand the potential health risk associated with their use Ensure that documentation of such training is made and kept on file Establishing emergency procedures to be followed if there is an overt spill or accident involving chemicals These procedures should be posted in a prominent place in the laboratory It is recommended that a responsible member of the laboratory staff be designated to handle emergencies whenever the principal investigator is absent from the premises Reporting any unusual incident such as a spill or release of a hazardous chemical to the Chemical Safety Director and either the department chairperson or director whichever is appropr
142. ontainer Always work on a surface protected by a disposable absorbent pad with impermeable backing e g Chux Absorbent side should face up The pad should be discarded if it becomes contaminated D Oral Administration of Hazardous D rugs 1 Oral tablets or capsules primarily pose a risk through direct skin contact with powder found on their surface or inside unit dose packs Oral liquids may be spilled accidentally 183 Appendix M Safe Handling of Hazardous Drugs Should you have to touch a tablet or capsule when preparing a patient dose wear latex gloves and place the tablet or capsule in a disposable medication cup Oral liquids can be administered in the amber glass dose container in which they are contained Gloves should be worn if manipulation e g dilution etc of the liquid is required The gloves empty unit dose packet and empty medication container should be placed in the hazardous drug chemotherapy waste container E Topical Administration of H azardous Drugs 1 Since topical creams ointments and patches are designed to be absorbed directly through intact skin administration should always be performed using gloves Dispose of contaminated dressing patches and other material in the hazardous drug waste container F Aerosol Administration of H azardous D rugs 1 184 Prior to aerosol administration of any cough inducing drug such as pentamidine patients should have proper diagno
143. oride Ferric glycerophosphate Ferric nitrate nonahydrate Ferric oxide Ferric oxide saccharated Ferric sulfate Ferrocene Ferrocyanide 10 Ferrosoferric oxide Fe304 Ferrous ammonium sulfate Ferrous bromide Ferrous chloride Ferrous iodide trihydrate Ferrous nitrate Ferrous oxalate Ferrous oxide Ferrous phosphate Ferrous sulfate Ferrous sulfide iron sulfide Ferrozine iron reagent Fetteling copper solution Ficoll Paque Fisher universal indicator Flaming red Flavianic acid hydrate Flavone Florisil Fluchloralin Fluoboric acid Fluoralloy 95 PPO Fluoranthrene Fluorenamine 2 Fluorene Fluorene 9 carboxylic acid Fluorenone 9 Fluorenyl acetamide N 2 Fluorescein Fluorescein diacetate 104 Explosion hazard H ighly reactive May form unstable peroxides on standing CPC CODE 19NH 1ITX 11TX 03CA 03CA 03CA 11TX 11TX 11TX 11TX 10TX 170X 11TX 1ITX 11TX 11TX 11TX 1ITX 11TX 11TX 03CA 11TX 170X 11TX 19NH 1ITX 11TX 11TX 10TX 10TX 10TX 10TX 10TX 03CA 10TX 19NH 10TX 03CA 10TX 10TX 10TX 10TX 03CA 10TX 10TX 19NH 10TX Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Fluorescein disodium salt 10TX Fluorescein isothiocyanate 14WS Fluoresceinamine 10TX Fluorine gas 07CG Fluoro 2 4 dinitrobenzene 1 10TX Fluoro 3 nitroaniline 4 08FL Fluoroacetamide 10TX Fluorobenzene 08FL Fluorobenzoic acid o 03CA Fluorodeoxyuridine 10TX Fluorohance contains
144. osphamide Cymene p Cypermethrin Cysteamine N acetic acid Cysteine hydrochloride Cysteine L Cytidine 3 monophosphate Cytidylic acid 3 Cytochalasin b Cytochrome c Cytodex 3 D 2 4 88 Explosion hazard Highly reactive May form unstable peroxides on standing CPC CODE 07CG 11TX 11TX 10TX 170X 11TX 03CA 02CB 10TX 08FL 19N H 08FL 08FL 03CA 03CA 10TX 08FL 08FL 08FL 08FL 08FL 10TX 10TX 10TX 10TX 08FL 03CA 10TX 08FL 08FL 08FL 08FL 08FL 08FL 10TX 08FL 10TX 10TX 10TX 19NH 10TX 10TX 10TX 10TX 19NH 10TX Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE D 19 developer 02CB Dalapon 03CA Dansyl aziridine 10TX Dansyl chloride 03CA Dansyl cysteine piperipini um salt 10TX Dansyl DL tryptophan 10TX Dansyl L cysteine 10TX Dansyl L glutamine 10TX Dansyl L proline 10TX Daunomycin 10TX DDA 3500 diesel additive O8FL DDI dimeryldiisocyanate 14WS DDT 10TX DEAE anion exchanger 10TX DEAE cellulose 10TX Deanol O8FL Deanol acetamidobenzoate 10TX Decahydronaphthalene O8FL Decalcifying solution contains EDTA 10TX Decalin O8FL Decane O8FL Decanoic acid 10TX Decanoyl chloride 02CB Decyl alcohol O8FL Decyl aldehyde decanal O8FL Decyl sodium sulfate 10TX Decylamine N O8FL Decylsuccinic anhydride 03CA Dehydroabietylamine 10TX Dehydroiso androsterone 10TX Dektol 10TX Demecoline 10TX Deoxyadenosine 10TX Desicate 10TX Desmodur 1 5 naphthalene diiso
145. oxides on standing Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Dihydroxybenzophenone 2 4 10TX Dihydroxyisonicotinic acid 2 6 Citrazinic acid 10TX Dihydroxynaphthalene 2 7 disulfonic acid sodium salt 4 5 10TX Dihydroxynaphthalenedisulfonic acid disodium salt 10TX Dihydroxyphenethylamine HCI 3 4 10TX Dihydroxypropyl theophylline 7 2 3 10TX Dihydroxypyrimidine 4 6 10TX Diiodobenzene m 10TX Diiodohexane 1 6 10TX Diiodo L tyrosine dihydrate 3 5 10TX Diiodomethane 10TX Diiodotyrosine dihydrate 3 5 10TX Diisobutylalumunium hydride 14WS Diisobutylamine OSFL Diisooctyl phthalate 10TX Diisopentylamine 10TX Diisopropyl fluorophosphate 10TX Diisopropyl ketone 2 4 dimethyl 3 pentanone O8FL Diisopropylamine O8FL Diisopropylethylamine O8FL Diisopropylethylenediamine N N 10TX Diisopropylfluorophosphate 10TX Diketene acetone adduct acetyl ketene 10TX Dimethoxy 1 propene 3 3 O8FL Dimethoxy 2 nitrobenzene 1 4 10TX Dimethoxyaniline 10TX Dimethoxybenzaldehyde 2 3 10TX Dimethoxybenzaldehyde 3 4 10TX Dimethoxybenzene p 10TX Dimethoxybenzidine dihydrochloride 3 3 10TX Dimethoxybenzidine 3 3 10TX Dimethoxybenzoic acid all isomers 10TX Dimethoxyethane 1 2 O8FL Dimethoxymethane O8FL Dimethoxy o phthalaldehydic acid 5 6 10TX Dimethoxyphenol 2 6 10TX Dimethoxyphenyethylamine HCI homoveratylamine 10TX Dimethoxyphenylacetyl chloride homoveratyl chloride 10TX Dimethoxypropane 2 2 15SS
146. pane 2 O8FL Chloro 2 nitroaniline 4 10TX Chloro 2 nitrobenzene 1 10TX Chloro 2 propanone O8FL Chloro 3 5 dimethyl phenol 4 10TX Chloro 4 4 5 5 tetramethyl 1 3 2 dioxarsolane 2 10TX Chloro 4 nitroaniline 2 10TX Chloro 4 nitrobenzene 1 10TX Chloroacetaldehyde O8FL Chloroacetaldehyde diethyl acetal O8FL Chloroacetaldehyde dimethyl acetal O8FL Chloroacetamide 10TX Chloroacetic acid 03CA Chloroacetic anhydride 03CA Chloroacetone 08FL Chloroacetone mono 08FL Chloroacetophenone alpha 10TX Chloroacetophenone p 10TX 82 Explosion hazard Highly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME Chloroacetyl chloride Chloroadenosine hemihydrate 2 Chloroaniline all isomers Chlorobenzaldehyde Chlorobenzamide Chlorobenzene Chlorobenzene sulfonic acid sodium salt p Chlorobenzene d5 Chlorobenzenesulfonamide 4 Chlorobenzenethiol Chlorobenzoic acid o nickel II salt Chlorobenzoic acid p Chlorobenzothiazole Chlorobenzotriazole Chlorobenzotrifluoride 2 Chlorobenzoyl chloride p Chlorobutane 1 Chlorobutane 2 Chlorobutyryl chloride Chlorocyclohexane Chlorodibenzyl phosphonate Chlorodifluoroacetic acid Chlorodimethylsilane Chloroethane ethyl chloride Chloroethanol 2 Chloroethyl acetate beta Chloroethyl mercury ceresan Chloroethyl phosphoric acid 2 Chloroethyl vinyl ether 2 Chloroform Chlorolose alpha Chloro m cresol 4 Chlor
147. posal container Contact Environmental Services and have the area cleaned again with soap and water Environmental Services personne should wear latex gloves while cleaning the area Wash water may be disposed of down the drain Dispose of gloves in the usual manner 4 A spill clean up video is availablein Nursing Staff Development CHEMICAL GENERIC NAME Altretamine Aminoglutethimide Azathioprine L Asparaginase Bleomycin Busulfan Carboplatin Carmustine Chlorambucil Chloramphenicol Chlorotrianisene Chlorozotocin Cyclosporin Cisplatin Cyclophosphamide Cytarabine Dacarbazine Dactinomycin Daunorubicin HCI Diethylstilbesterol Doxorubicin HCI OSHA Hazardous Drugs TRADE NAME H exalen Cytadren Imuran Elspar Blenoxane M yleran Paraplatin BICNU Leukeran Chloromycetin OCU Chlor AK Chlor Chloroptic TACE Sandimmune N eoral Platinol Cytoxan N eosar Cytosar U Tarabine PFS DTIC Dome Cosmegen Cerubidine Diethylstil besterol Adriamycin RDF Adriamycin PFS Rubex 187 Appendix M Safe Handling of Hazardous Drugs Estradiol Estramustine Ethinyl Estradiol Etoposide Floxuridine Finasteride Fluorouracil Flutamide Gancyclovir Na H ydroxyurea Idarubicin Ifosfamide Interferon Alfa Isotretinoin Leuprolide A cetate Levamisole HCI Lomustine Mechlorethamine H Cl M edroxyprogesterone A cetate M egestrol A cetate Melphalan Mercaptopurine Methotrexate N a Mitomycin
148. ppointed by the chemical hygiene officer is responsible for the following 2 6 1 Creating and maintaining a chemical inventory 2 6 2 Maintaining access to MSDSs 2 6 3 Conducting and maintaining records of training Employees Employees are responsible for the following 2 7 1 Practicing safe procedures in the workplace as outlined in the Chemical Safety and Waste M anagement M anual 2 7 2 Notifying their supervisor of unsafe conditions or practices observed 3 BASIC SAFETY RULES FOR WORKING WITH CHEMICALS 3 1 General Rules To be used for essentially all laboratory or clinical work with chemicals 3 1 1 3 1 2 3 1 3 3 1 4 3 1 6 3 1 8 Avoid Routine Exposure Minimize exposure by any route Do not smal or taste chemicals Minimize skin contact Vent any apparatus that might give off toxic chemicals i e vacuum pumps distillation columns into local exhaust system Inspect glove boxes and gloves before use Avoid Horseplay Do not engagein any behavior that may distract another worker Personal Protection Safety glasses with side shields or goggles should be worn by all persons in the lab including visitors Wear appropriate gloves inspect and replace them as necessary If possible do not wear contact lenses in the laboratory If contacts must be worn inform supervisor so precautions can be taken Choice of Chemicals Use only those chemicals for which available ventilation and safety equipment
149. pt to treat photographic wastes Do not neutralize alkaline developer solutions with stop bath or any other materials do not attempt to neutralize fixing baths with acids Waste treatment in labs is not allowed at UAB and these operations can lead to hazardous by products 3 Fixers contain some silver which must be treated or recovered before it can be disposed of Used photographic fixer may be picked up for recycling by Hazardous Material Facility personnel Contact HMF at 4 3797 for containers and to schedule pickup Itisimportant to remember that when handling fixers developer or other photographic products that proper Personal Protective Equi pment PPE be worn at all times At a minimum all lab workers should wear appropriate footwear lab coat surgical type disposable gloves preferably nitrile and safety glasses when handling these hazardous chemicals 180 Appendix M Safe Handling of Hazardous Drugs RATIONALE In 1986 the Occupational Safety and Health Administration OSHA in response to many inquiries published guidelines for the management of antineoplastic drugs in the workplace At that time surveys indicated little standardization in the use of engineering controls and personal protective equipment in avoiding contact with these agents Although practices have improved in subsequent years problems continue to exist Since the first guidelines the occupational management of cytotoxic chemicals has been further
150. ratory required for work involving those substances Extremely H azardous Substance Supplemental Controls Designated Areas Containment Devices Decontamination Procedures Attach any relevant documentation pertaining to the use of select agents as defined in 42 CFR 72 175 176 Appendix Chemical Hygiene Plan Outline This plan shall be made available to laboratory personnel or their representatives to representatives of the UAB Department of Occupational Health and Safety and to representatives of those granting and accreditation agencies associated with this laboratory Appendix K Disposal of Ethidium Bromide 1 Ethidium bromide solutions may be collected and manifested for pick up by HMF personnel 2 Commercially available filters designed to remove ethidium bromide from solutions may be used The filtered buffer solution may be poured down the drain 3 Ethidium bromide may be neutralized using the Lunn and Sansone method below Neutralization with bleach is not recommended since mutagenic by products may remain in the solution Spent filters and gels containing ethidium bromide should be disposed of in yellow hazardous waste disposal bags or Chemogators for incineration Regular red biohazard bags should not be used Destruction of Ethidium Bromide Required reagents 5 hypophosphorous acid 0 5M sodium nitrate solution Sodium bicarbonate pH paper The following steps should be carried out in a
151. re the temperature does not exceed 125 F Cylinders must be secured in an upright position Cylinders not in use should have the valve protection caps in place The maintenance department will install wall brackets chains or non elastic straps for securing cylinders 4 7 4 6 Never mix chemicals unless such mixing is part of a documented and approved procedure Transportation 4 8 1 4 8 2 4 8 3 4 8 4 4 8 5 All chemicals should be labeled before being transported When chemicals are hand carried they should be placed in an outside container or acid carrying bucket to protect against breakage and spill age When chemicals are transported by wheeled cart the cart should be stable under the load and have wheels large enough to negotiate uneven surfaces such as expansion joints and floor drain depressions without tipping or stopping suddenly Incompatible chemicals should never be transported on the same cart Laboratory moves and transfers of large amounts of chemicals must be coordinated through the Hazardous Materials Facility It is illegal to ship hazardous materials by common carrier unless Department of Transportation regulations are followed Secondary containment should always be used to contain substances if there is a break in the primary container 4 8 6 To avoid exposure to persons on passenger elevators if 4 8 7 4 8 8 4 8 9 practical chemicals should be transported on freight eevators only T
152. rgents Follow normal disinfection procedures G Disposal of H azardous Drugs 1 After a hazardous drug has been administered remove syringes tubing and other equipment using an absorbent pad with impermeable backing to prevent droplet contamination All syringes IV tubing and supplies associated with the administration of the hazardous agent should be disposed in the hazardous drug chemotherapy disposal container notin the regular sharps container or the medical waste container Hazardous drug chemotherapy disposal containers should remain closed when not in use and should be changed before having to force discards into them 2 Wash hands after removing protective clothing and equipment In the event any drug is splashed on unprotected skin wash the area immediately renove contaminated clothing and contact your supervisor Medical attention and consultation should be sought concerning the incident and an incident report should be filled out See Section J Contaminated clothing should be taken home in a plastic bag and washed separately from other clothing H Handling Storage and Disposal of Waste C ontainers 1 Hazardous drug waste should be disposed of only in designated hazardous drug chemotherapy waste containers Hazardous drug chemotherapy waste containers come in 2 sizes five 5 and thirteen 13 gallon and may be obtained from Materials Management Waste containers should not be stored in the corridors Containe
153. rom the Department of Occupational Health amp Safety web page at http healthsafe uab edu or from the Division of Biosafety at 4 2487 The following toxins are covered under this legislation Abrin Aflatoxins Botulinum toxins Clostridium perfringens epsilon toxin Conotoxins Diacetoxyscirpenol Ricin Saxitoxin Shigatoxin Staphylococcal enterotoxi ns Tetrodotoxin T 2toxin 3 3 2 Those planning to do research involving these agents must register with the Department of Occupational Health and Safety Depending on the specific type of toxin registration directly with the CDC may be required Call 4 2487 for assistance in registration Safe Handling Procedures for Administering H azardous Drugs 3 41 The occupational management of cytotoxic chemicals has been darified by the OSHA Hazard Communication Standard 29CFR1910 1200 In order to provide recommendations consistent with current scientific knowledge OSHA has published new expanded informational guidelines dealing with controlling exposure to hazardous drugs in addition to cytotoxic agents These guidelines are summarized in Appendix M 3 4 2 The following criteria for deeming a drug as hazardous were developed by the American Society of Hospital Pharmacists and were used as the basis for new guidelines genotoxicity e carcinogenicity teratogenicity or infertility impairment serious organ or other toxic manifestation at low doses in experimental animals
154. rosulfonic acid Grignard reagents Metal hydrides Li Al K Na Ca LIAI Nitric acid above 40 solution Peroxidizable chemicals Phosphorus oxychloride Phosphorus pentoxide Silanes e g hexamethyl disilane Sulfuryl chloride Thionyl chloride Acyl halides Anhydrous metal halides Al As Fe P S Sb Sn Ti 59 Appendix B Highly Reactive Compounds Peroxide Forming Compounds 60 Organic peroxides are a dangerous fire hazard if allowed to react with reducing agents They are powerful oxidizers and are a severe explosion hazard when shocked exposed to heat or if they undergo a spontaneous chemical reaction Upon contact with some reducing agents explosions can occur Many peroxides commonly handled in laboratories are far more sensitive to shock than most primary explosives e g TNT Many laboratory chemicals can form peroxides particularly when exposed to air Containers used for storage of peroxidizable compounds or retention of materials that become hazardous upon prolonged storage shall be limited to a maximum of six months after opening Containers must then be disposed of in a safe manner All opened containers of such materials should be tested every three months for peroxides Peroxidizable materials must be labeled upon receipt The date of receipt and the date when the container was opened must be prominently displayed Sample Peroxidizable Compound Label PEROXIDIZABLE COMPOUND NAME DATE RECEIVED
155. rous sweeping or other actions that might generate respirable dust Clean or dispose of contaminated materials properly Large Chemical Spills 500 ml or more 9 31 In case of a large spill of a known hazardous chemical contain the spill if possible warn others restrict access and evacuate the area Contact the H azardous Materials M anager at 4 3797 immediately and give your name extension location of spill as well as the quantity and name of the chemical spilled Decontaminate personnel that may have been splashed with the chemical and contact physicians at The Workplace 933 5300 Contact with corrosive materials requires immediate attention Know the location of safety showers and eyewashes in your area An Accident Injury Report Form should be completed and a copy forwarded to the Department of Risk Management The Hazardous Materials Manager will contact the spill response team which will have full authority over the clean up operation The spill response team has been specially trained to handle hazardous chemical spills Anyone deliberately breaching the authority of the spill response team at the site of a spill thereby jeopardizing the health and safety of other UAB employees may be subject to disciplinary action The Hazardous Materials Manager or his designee will be responsible for calling any additional personnel needed at the site of the spill Mercury Spills Mercury is commonly used throughout the Univers
156. rs may cause methemoglobi nemia an acute anemia resulting from converting the iron of hemoglobin into a form that cannot transport oxygen Precautions Useliquid chemistry whenever possible rather than mixing developing powders to avoid inhalation exposure to powdered developer When mixing powdered developers use a chemical fume hood or local exhaust ventilation In any case there should be adequate dilution ventilation if no local exhaust ventilation is provided Wear gloves goggles and protective apron when mixing concentrated photographic chemicals Always add any acid to water never the reverse An eyewash fountain and emergency shower facility should be available wherethe chemicals are mixed dueto the corrosive alkali in developers and because of the glacial acetic acid In case of skin or eye contact rinse for at least 15 20 minutes and call a physician Store concentrated acids and other corrosive chemicals on low shelves to reduce the chance of face or eye damage in case of breakage and splashing Do not store photographic solutions in glass containers Label all solutions carefully Waste Disposal Requirements L Old or unused photographic chemical solutions toning solutions ferricyanide solutions chromium solutions color processing solutions developer stop baths and fixer should be treated as hazardous waste 179 Appendix L Management of Photographic Chemicals 2 Never attem
157. rs may be stored in patient rooms after patient and family members have been counseled on the specific hazards of the chemicals Containers may also be stored with other medical waste but should not be mixed 2 Once the waste container becomes full Environmental Services or other healthcare personnel wearing latex gloves take the container to the designated medical waste storage area to be placed in the yellow medical waste barrels Waste in yellow barrels is designated for disposal by incineration Barrels can be obtained from the Hazardous Materials Facility by calling 4 3797 I Handling of Contaminated Linen 185 Appendix M Safe Handling of Hazardous Drugs 1 Personnel handling linen contaminated with hazardous drugs blood vomits or excreta from patients who have received hazardous drugs up to 48 hours before should wear gloves gown and face shield Gloves alone may be acceptable if contamination is dry or not dripping Linen should be placed in a specially marked yellow laundry bag which may be obtained from Linen Service This laundry bag and its contents should be prewashed and then the linens may be added to other laundry for an additional wash J Exposure Employee H ealth Procedure 1 Identify all trained personnel who are assigned to prepare or administer hazardous drugs An exposure should always be documented by filling out an accident incident report so exposure may be properly tracked 2 Procedure for h
158. ructions on Reverse Side Print or Type Only HAZARDOUS MATERIALS FACILITY USE ONLY EPA Generator ALD06 369 0705 Technician s Date Transported 1 Generator Name 2 Generator Number p 3 Building 3 Room 4 Telephone 5 Date 6 Department 7 Person Completing Manifest 8 Chemical 8 Chemical Compound er line This is to certify that the above named articles are properly classified described packaged marked and labeled and are in proper condition for transportation according to applicable requirements of the UAB Chemical Safety and Waste Management Program and the Department of Transportation Improper information regarding the transport of hazardous materials over public roads or highways constitutes violation of State and Federal laws which could result in civil or criminal penalties 16 Generator Signature Date Send top copy to the Hazardous Materials Facility Attach middle copy to the box Retain bottom copy for your records THE UNIVERSITY OF ALABAMA AT BIRMINGHAM INCIDENT REPORT FORM Incidents involving employees students visitors This is a confidential report and should not be made a part of an employee s personnel record It is completed to allow us to obtain advice from legal counsel and for the protection of the university and it s employees from potential liability re PLEASE PRINT LEGIBLY INFORMATION ABOUT THE PERSON INVOLVED IN THE INCIDENT Full Name Soc
159. s part of compliance with the UAB Health and Safety program or Federal requirements This section summarizes the kinds of records kept and by whom Hazardous chemical inventories and MSDS files are kept and maintained by chemical hygiene officers or principal investigators within individual departments Environmental monitoring records are maintained by the Department of Occupational Health and Safety and chemical hygiene officers within individual departments Medical records and consultation records are maintained by The Workplace Training records are maintained by chemical hygiene officers or principal investigators within the individual departments Records of required training conducted through the Department of Occupational Health and Safety are also maintained by the Human Resources Department Fume hood certification records are maintained by the Department of Occupational Health and Safety Division of Biosafety 4 7 Chemical Storage 4 7 1 The chemical storage area should be posted with an 4 7 2 4 7 3 appropriate sign Chemicals must be stored in appropriate containers and correctly labeled Chemical compatibility must be determined to reduce the likelihood of hazardous reactions The following steps should be followed when assessing chemical compatibility 4 7 3 1 Identify the chemical 4 7 3 2 Determine the Hazard Class of the chemical Toxic Flammable Reactive Corrosive Oxidizer Low Hazard
160. senic trioxide Arsenic trisulfide Arsenic solid Arsenous acid Arsonic acid methyl monosodium salt Asbestos Ascaridole Ascorbic acid Asparagine hydrate L Asparagine L Aspartic acid Atropine sulfate Auramine O Aurin tricarboxylic acid Aurintricarboxylic acid ammonium salt Azaguanine 8 Azaserine Azelaic acid Azo bis isobutyronitrile 2 2 Azobenzene Azobis 2 methylpropionitrile 2 2 Azoene fast violet Azoxybenzene Azoxydianisole 4 4 AzureA Bacto phenol red Barbital Barbituric acid Barium Barium acetate Barium carbonate Barium chlorate monohydrate 72 Explosion hazard H ighly reactive May form unstable peroxides on standing CPC CODE O8FL 10TX 19NH 19NH 19NH 19NH 07CG 08FL 11TX 11TX 03CA 11TX 11TX 14WS 03CA 11TX 11TX 11TX 170X 10TX 11TX 1555 19NH 19NH 19NH 19NH 10TX 10TX 03CA 10TX 10TX 10TX 10TX 1555 10TX 1555 10TX 10TX 10TX 10TX 10TX 10TX 10TX 11TX 10TX LITX 170X Appendix D UAB Waste Registry CHEMICAL NAME Barium chloride Barium chromate Barium cyanide Barium diphenylamine sulfamate Barium fluoride Barium hydroxide Barium metaborate monohydrate Barium nitrate Barium oxalate Barium oxide Barium peroxide anhydrous Barium stearate Barium sulfate Barium sulfide Barium titanate Basic fuchsin Batson s 17 blue pigment Batson s 17 catalyst Batson s 17 promoter Batson s 17 red pigment Bensul
161. showers are tested by the maintenance department and tagged at the time of inspection 172 Appendix Chemical Hygiene Plan Outline Protective Equipment Location M ethod Used to Verify Performance IV Information and Training This is to document that personnel in this laboratory have been trained in the following as required by the UAB Chemical Safety and Waste M anagement Program e The requirements of the Hazard Communication and Chemical Safety and Waste M anagement Programs e Basic chemical handling and laboratory safety procedures Physical and health hazards of chemicals How toread and interpret labels and material safety data sheets M SDS s e Thelocation and availability of the written program M SDS s the hazardous chemical inventory and methods of personal protection Attach an outline or summary of any additional training required in this laboratory as well as the frequency of such training 173 Appendix Chemical Hygiene Plan Outline V Circumstances Requiring Prior A pproval Thefollowing procedures and activities require prior approval Activity Approval Procedure Person Authorized to Grant Approval VI Medical Consultation and Examination Laboratory personnel will havethe opportunity to receive medical consultation and examination under the following circumstances e Development of signs or symptoms of exposure to a hazardous chemical used in the laboratory e Environmental
162. specially gloves to prevent skin contact If you are pregnant notify your supervisor and consult your physician before working with these materials The following chemicals are designated by the University as Extremely Hazardous Substances This designation is based on 1 The potential of the agent to cause severe injury or death in low concentration 2 The potential to cause death or injury to large numbers of people if released 3 The agent s suspected ability to induce or promote cancer This list is not all inclusive Other chemical agents that have similar properties or mode of action should be handled with the same precautions 11 12 4 Aminobiphenyl Arsenic organic arsenic and derivatives Arsine and gaseous derivatives Asbestos Azathioprine Benzidine and derivatives Bis chloromethyl ether and Chloromethyl ether 1 1 bis p chlorophenyl 2 2 2 trichloroethane DDT Bromodeoxyuridine 1 4 Butanediol dimethylsulfonate M yleran N Butyl N 4 hydroxybutyl nitrosamine OH BBN Chlorambucil Chloropicrin in gas mixtures Cyanogen Cyanogen chloride Cyclophosphamide Diborane Diisopropylfluorophosphate 9 10 Dimethyl 1 2 benzanthracene DM BA Erionite Germane H exaethyltetraphosphate Hydrogen cyanide Hydrogen selenide Melphalan N Methyl N benzylnitrosamine N Methyl N nitrosourea Mustard Gas 2 N apthylamine Nitric oxide Nitrogen dioxide Nitrogen tetroxide Parathion Phosgene Phosphine P
163. stance capable of causing cancer Chronic An adverse effect with symptoms that develop slowly over along period or that frequently recur Department of Occupational Health and Safety DOH S The department which provides technical support for the operation of the UAB Hazardous Materials Facility as well as the UAB Chemical Safety and Waste Management Program This department also establishes health and safety standards to protect visitors and employees of UAB Department of Transportation DOT The federal agency responsible for policies and procedures governing the transport of materials including hazardous chemical wastes Environmental Protection Agency EPA The federal agency responsible for enforcement of policies and procedures governing the generation handling and disposal of hazardous chemical waste Flash Point The minimum temperature at which a material gives off vapor within a test vessel in sufficient concentration to form an ignitable mixture with air near the surface of the material Generator A person or group within UAB which produces chemical waste Hazardous Chemical Waste Any discarded chemical of a solid liquid or gaseous form that is defined according to government regulations as a Corrosive A material that causes visible destruction or irreversible alterations in human skin at the site of contact Corrosives have a pH 2 or 2 12 5 2 Flammable For the purposes of the chemical waste program
164. stic screening to rule out undiagnosed mycobacterium tuberculosis TB This should be carried out according to the UAB tuberculosis exposure control guidelines Administration of aerosolized hazardous drugs should take place in an isolation room with a minimum of 6 air changes per hour The isolation room should be 100 exhaust and airflow should be negative with respect to the corridor air should flow into the room with the door closed Air flow should be verified by hospital maintenance During aerosol administration of a hazardous drug a warning sign should be placed on the patients door to warn others that proper personal protective equipment is required before entering This should be done by the person responsible for the administration of the drug Personal protective equipment PPE should consist of a closed front gown gloves and a NIOSH approved particulate air respirator which has been properly fit tested Other than for patient emergencies employees should avoid returning to the patients room without PPE for a period of at least thirty 30 minutes following administration of the drug Hazardous drugs are particulate not volatile and will settle out over time Appendix M Safe Handling of Hazardous Drugs 5 Disposable material associated with the administration should be placed in the hazardous drug chemotherapy waste container Non disposable items may be properly cleaned of the drug with most hospital dete
165. t Anethole trans Aniline Phenylamine Aminobenzene Aniline blue Aniline hydrochloride Aniline hydrogen phthalate Aniline oil liquid Aniline sulfate Anisaldehyde Anisaldehyde o Anisaldehyde p Anisic acid p Anisidine all isomers Anisole Anisoyl chloride Anthracene Anthraldehyde hydrate Anthranilic acid Anthraquinone Anthraquinone sulfonic acid 2 sodium salt Anthraquinonesulfonic acid 2 Anthrone Antifoam A emulsion Antimony Antimony pentachloride Antimony pentafluoride Antimony potassium tartrate Antimony trichloride Antimony trioxide Antimony trisulfide Antipyrine Antipyrine 4 amino Anysyl alcohol mixed isomers Aquasol 2 contains xylene Arabinose L Explosion hazard H ighly reactive May form unstable peroxides on standing CPC CODE 10TX 10TX 08FL 08FL 08FL 08FL 08FL 10TX 08FL 08FL 19NH 08FL 08FL 08FL 10TX 10TX 10TX 10TX 08FL 10TX 08FL 08FL 08FL 10TX 10TX 08FL 14WS 10TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX 11TX 14WS 14WS 11TX 14WS 11TX 14WS 10TX 10TX 10TX 08FL 19NH 71 Appendix D UAB Waste Registry CHEMICAL NAME Araldite Arecoline hydrochloride Arginine hydrochloride Arginine monohydrate L Arginine monohydrochloride Arginine L Argon Aromatic petroleum distillates Arsanilic acid o Arsanilic acid p Arsenic acid solution Arsenic acid sodium salt Arsenic pentoxide Arsenic trichloride Arsenic triiodide Ar
166. t Unit DWM gt DWM DWM DWM DWM V IV IV IV z lz lz z z 10 List 5 chemicals that are most frequently used in the laboratory and the maximum quantity stored and the frequency of use Name Frequency Amount Unit DW M35 DW M5 DW M35 DWM gt DWM gt SSIS IIS 11 Are regulated agents i e select agents or controlled substances used in your lab Agent Bldg Used Room Used Bldg Stored Room Stored 11 99 Appendix I Audit Forms Laboratory Monitoring Form Page 2 of 3 1 Is there evidence of documented safety training Is training provided by P I Lab Coordinator Video External H amp S Other 2 Is there evidence of documented participation in an occupational medicine program 3 Do UAB employees have access to UAB safety manuals 4 Has a lab specific safety plan been written that addressed the items checked in section A 1 Do personnel wear appropriate clothing and PPE for work being performed 2 Are spill kits available where appropriate 3 Are first aid kits available where appropriate 4 Are electrical circuits properly loaded with no cords across isles 5 Are fire extinguishers available tested unobstructed mounted 6 Are aisles passageways and exits within the lab clear from obstruction 7 a Are all gas cylinders securely restrained b Are valve covers on those not in use 8 Are foods and
167. t drug screening will be performed as required by the UAB On the Job Injury IIIness Program policy Failure to submit to drug screen may result in termination of employment THIS FORM SHOULD NOT BE USED FOR UAHSF EMPLOYEES This UAB employee _ C full name of employee and social security number is referred to for evaluation of the injury medical service provider illness described below An incident report must be completed and submitted as required by the On the Job Injury IlIness Program policy or refer to Human Resources web sit at www hrm uab edu Employee s Department Employee s Position Title Date incident occurred Brief description of incident and resulting injury or illness Employee Signature Date signed Supervisor Signature Date signed Supervisor Phone Number Completion of this form does not certify that the injury or illness described above is an On the Job Injury lliness OJI qualifying for benefits under the UAB On The Job Injury lllness Program An application for OJI benefits must be completed signed and submitted to Hilb Rogal amp Hamilton HRH A copy of the application and further information regarding the OJI program may be accessed on the web at www hrm uab edu or by contacting Rosalind Bothwell with HRH at 868 0288 V 3 6 02 Appendix G Protective Gloves There are several types of rubber surgeons or laboratory gloves available on the market Each is made fr
168. tain compliance with the United States Department of Transportation DOT and Environmental Protection A gency EPA regulations regarding packing labeling and disposal of hazardous chemical waste In addition the Alabama Department of Environmental Management ADEM and the Jefferson County Commission regulate chemical waste disposal via the sanitary sewer system At UAB the Department of Occupational Health and Safety has the primary responsibility for the safe and legal management of hazardous chemical waste and provides the service for proper removal and disposal However it is also the legal and ethical responsibility of each department head faculty member and laboratory director as generators to assure that the management of hazardous chemical waste from each component under his her supervision follows the proper disposal process In addition to chemical waste there are four other types of waste generated at UAB Please consult the appropriate procedure manuals for disposal of these wastes 11 2 3 1 Universal waste Examples batteries pesticides mercury containing lamps and devices 11232 Low level radioactive waste Examples radioactive solid liquid and animal waste 11 233 Biohazardous infectious waste Examples infectious laboratory cultures oncogenic viruses infectious human and animal waste 11 2 3 4 Non hazardous solid waste Examples garbage rubbish paper or cardboard refuse non contaminated glass
169. tane 08FL Bromoethane 08FL Bromoethyl benzene 08FL Bromoethylphthalimide beta 10TX Bromoform 10TX Bromohexadecane 10TX Bromohexane 1 O8FL Bromoisobutyric acid 2 03CA Bromomethyl butane 08FL Bromomethyl butene 10TX Bromomethyl propane 08FL Bromonaphthalene alpha 08FL Bromonaphthyl glucopyranoside 10TX Bromooctane 10TX Bromopentane O8FL Bromophenacyl bromide p 10TX Bromophenol blue 10TX Bromophenol o O8FL Bromophenyl isocyanate p 14WS Bromophenyl phenyl ether 4 10TX Bromophenylacetonitrile 2 O8FL Bromophenylhydrazine hydrochloride p 10TX Bromo p nitrotoluene alpha 03CA Bromo p phenylacetophenone alpha 10TX Bromopropane 1 O8FL Bromopropane 2 O8FL Bromopropene allyl bromide O8FL Bromopropionic acid 2 03CA Bromo p tolunitrile alpha 02CB Bromosalicylic acid 5 10TX Explosion hazard 71 Highly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME Bromosuccinimide N Bromothiophene 2 Bromothymol blue Bromotoluene alpha Bromoundecanoic acid 11 Bromphenol blue Bromsulfalein Brucine hydrate Brucine sulfate Brucine sulfate hydrate Brucine solid Budget solve Buffalo black nbr Butadiene diepoxide Butadiene monoxide Butadiene sulfone Butanal Butane Butane 2 Butanediol diglycidyl ether 1 4 Butanediol all isomers Butanedione monoxime Butanedione 2 3 Butanedione 2 oxime 2 3 Butanethiol 1 butyl mercaptan
170. te 10TX Naphthol blue 10TX Naphthol blue black Acid black 10TX Naphthol chloroacetate 10TX Naphthol phosphate 10TX Naphthol phosphoric acid 10TX Naphthol yellow S 10TX N aphthol bi N acetyl D glucosaminide 10TX Naphthol D glucuronic acid 10TX Explosion hazard 123 H ighly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Naphthoquinone 4 sulfonic acid potassium salt 1 2 10TX Naphthoquinone 1 2 10TX Naphthoquinone 1 4 10TX Naphthoquinone 4 sulfonic acid sodium salt 1 2 10TX Naphthoxyacetic acid beta 10TX Naphthyl acetate alpha 10TX Naphthyl acetonitrile 10TX Naphthyl acid phosphate alpha 10TX Naphthyl isocyanate 1 14WS Naphthyl isocyanate alpha 14WS Naphthyl isothiocyanate 10TX Naphthylacetamide alpha 10TX Naphthylacetic acid 1 03CA Naphthylacetic acid 2 03CA Naphthylamine hydrochloride 10TX Naphthylamine 1 10TX Naphthylamine alpha 10TX Naphthylamine beta 10TX Naphthylene acetic acid 1 03CA Naphthylhydrazine hydrochloride 1 10TX Naphthylthiourea alpha 10TX Naproxen 10TX Naptalam 10TX Napthyl acetate 1 10TX N benzoyl l arginine ethylester 10TX N benzoyI I tyrosine ethylester 10TX NCS tissue solubilizer 0 6N quaternary ammonia in toluene O8FL N eocinchophen 10TX N eocuproine hydrate 10TX Neodymium chloride hexahydrate 11TX N ethyl 1 naphthylamine 10TX Neutral red 10TX New methylene blue basic blue 10TX Newsorb waste a
171. terial Safety Data Sheets MSDS 4 5 4 4 1 4 4 2 4 4 3 4 4 4 The chemical hygiene officer must obtain a current MSDS from the manufacturer for all hazardous chemicals or ensure that they are available electronically CD ROM Internet These sheets contain information on the health and physical hazards and proper handling procedures for these chemicals Sometimes the information on the MSDS may be inadequate for the particular situation or may need interpretation In these cases the Chemical Safety Director should be contacted for assistance Consumer products used as they would be at home do not require an MSDS present in the file However if the material is frequently used used in large quantity or used in a way other than that expected from a consumer an MSDS should be kept on file Sources of MSDSs include the chemical supplier the chemical manufacturer and various Internet resources Internet sources may be accessed through the Department of Occupational Health amp Safety web page at http healthsafe uab edu Contact Chemical Safety if an MSDS cannot be obtained from these sources The MSDS file must be readily accessible to all enployees This file must be updated routinely to account for MSDS changes and the addition of new chemicals Labels and Signs 4 5 1 4 5 3 All hazardous chemicals are required by law to be labeled by the manufacturer The chemical hygiene officer must ensure that each existi
172. the manifest if material is unopened 11 5 2 3 The generator should check the information on the manifest sign his or her name and attach it to the corresponding box 11 5 3 Step Three Chemical Waste Removal To have chemical waste removed mail the top copy of the manifest to the address below HAZARDOUS MATERIALS FACILITY HMF 221 14th Street South UAB Campus Mail 0001 Attach one copy to the box and retain a copy for the laboratory records Specify where the waste is to be picked up Ensure that HMF personne will have access to the area where the waste is held for pick up If your waste is not picked up in a reasonable period of time call 43797 to inquire about the delay Any incomplete or improperly completed manifest will be returned to the generator with an explanation for its return 12 UNIVERSAL WASTE UAB is a large quantity handler of Universal Waste This means that the institution stores more than 5000 kg or 11000 Ibs of the materials listed below Items classified as Universal Waste are reported to the Alabama Department of Environmental Management under 8700 20 Batteries Pesticides Fluorescent tubes Mercury containing devices Ballasts Ballasts are not generally treated as Universal Waste but the contract UAB has with the recycling company requires that they be managed as such Containers of Universal Waste must be labeled with the name of the material and date of accumulation and the address of the gen
173. thyl caprolactim o Methyl carbamate Methyl cellosolve Methyl cellulose Methyl chloride gas Methyl chloroacetate Methyl chloroformate Methyl cinnamate Methyl cyclohexane Methyl cyclohexanone Methyl ethyl ketone Methyl ethyl ketone peroxide Methyl fluorescein 3 0 Methyl formamide N Methyl formate Methyl furan Methyl gallate Methyl green Methyl isoamyl ketone Methyl isobutyl ketone Methyl isobutyrate Methyl isocyanate Methyl lactate Methyl laurate Methyl lithium Methyl mercaptan methanethiol Methyl mercury Methyl mercury hydroxide Methyl methacrylate Methyl methanesulfonate Methyl methanethiolsulfonate Methyl nonanoate methyl pelargonate Methyl octanoate Methyl oleate Methyl orange Methyl orange sodium salt Methyl palmitate Methyl parathion liquid Methyl phthalate Methyl phthalyl ethyl glycolate Methyl p hydroxybenzoate Methyl picolinate Methyl propionate Methyl p toluenesulfonate Explosion hazard H ighly reactive May form unstable peroxides on standing CPC CODE 07CG O8FL O8FL 10TX 10TX 08FL 19NH 07CG 08FL 14WS 08FL 08FL 08FL 08FL 1555 10TX 08FL 08FL 08FL 10TX 10TX 08FL 08FL 08FL 08FL 14WS 19NH 14WS OSFL 11TX 11TX 08FL 10TX 08FL 10TX 10TX 10TX 10TX 10TX 19NH 10TX 10TX 08FL 10TX 08FL 08FL 10TX 119 Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Methyl pyrrolidone N O8FL Methyl red 10TX Methyl sali
174. thyl dihydro trimethyl pyridine Diethyl ether Ether Diethyl ethoxymethylenemalonate Diethyl ethylenediamine Diethyl formamidomalonate Diethyl glycol monoether acetate Diethyl ketone Diethyl maleate Diethyl malonate Diethyl o pyrazinyl phosphorothioate 0 0 Diethyl oxalate Diethyl phenyImalonate Diethyl phosphite Diethyl phthalate Diethyl p nitrophenyl phosphate Diethyl propanediamine Diethyl pyrocarbonate Diethyl selenide Diethyl succinate Diethyl sulfate Diethyl sulfite Diethyl 2 1 naphthoxy propionamide N N Diethyl 2 2 dicarbcyanine iodide 1 1 Diethylacetamide N N Diethylamine Diethylamine hydrochloride Diethylamino ethane thiol hydrochloride Diethylamino 1 propanol 3 Diethylaminoethanol 2 Diethylaminophenol m Diethylaminopropylamine 3 Diethylaminosulfur trifluoride DAST Explosion hazard H ighly reactive May form unstable peroxides on standing CPC CODE 10TX 10TX 08FL 10TX 08FL 10TX 08FL 08FL 08FL 10TX 10TX 10TX 08FL 10TX 08FL 10TX 08FL 08FL 08FL 10TX 08FL 08FL 08FL 10TX 10TX 08FL 08FL 08FL 08FL 10TX 08FL 08FL 10TX 08FL 08FL 08FL 10TX 10TX 10TX 08FL 10TX 10TX 08FL 08FL 09FS 02CB 08FL 93 Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Diethylaniline N N OSFL Diethylarsine 14WS Diethylazodicarboxylate 10TX Diethylcarbamazine 10TX Diethylcarbamazine citrate 10TX Diethylcyclohexylamine O8FL Diethyl
175. thylenediamine tetraacetic acid Ethylenediamine trifluoroacetic acid 2 hydroxpropyl Ethylenediaminetetraacetic acid disodium salt Ethylenediaminetetraethanol tetrahydroxyethyl ethylenediamine Ethylenedinitrolotetraacetic acid dipotassium salt Ethylenedinitrolotetraacetic acid tetrasodium salt Ethylenethiourea Ethylenimine Ethyl hexanediol Ethylhexanol 2 Ethylhexylamine 2 Ethylmaleimide N Ethylmercuric phosphate EthyImercurithiosalicylic acid sodium salt EthyImorpholine N Ethyl m toluidine N Ethyl N heptanoate Ethyl o toluidine N N ethyl o aniline Ethylphenol all isomers Ethylpropyl 3 4 dimethyl 2 6 dinitroaniline N 1 Ethylurea Ethylxanthic acid potassium salt Eucalyptol Eugenol Evan s blue Fast Blue RR salt Fast garnet stain Fast green Fat red Sudan red 7B Explosion hazard Highly reactive May form unstable peroxides on standing CPC CODE 10TX 03CA 10TX 08FL 08FL 10TX 08FL 10TX 10TX 08FL 10TX 08FL 08FL 03CA 08FL 08FL 02CB 10TX 10TX 10TX 10TX 10TX 10TX 10TX 10TX 08FL 10TX 08FL 08FL 09FS 11TX 11TX 08FL 08FL 08FL 08FL 10TX 10TX 10TX 10TX 08FL 10TX 10TX 10TX 10TX 10TX 10TX 103 Appendix D UAB Waste Registry CHEMICAL NAME FD amp C green 3 powder Ferric ammonium chromate Ferric ammonium citrate Ferric ammonium sulfate Ferric chloride Ferric chloride hexahydrate Ferric citrate Ferric cyanide 10 Ferric ferrocyanide Ferric flu
176. times if a chemical in use is highly toxic or of unknown toxicity 3 25 Spills and Accidents Notify supervisor of all incidents of exposure or spills consult a qualified physician when appropriate If a major spill of an extremely hazardous substance occurs outside the hood evacuate the area restrict access and call the Chemical Safety Director at extension 4 2487 A major spill of a carcinogen or material of high or unknown toxicity would be the release of any quantity of a gaseous agent greater than 200 ml of a liquid or more than 100 milligrams of a powder that could produce inhalable dust For spills of other hazardous substances a large spill is one of 500 ml or more See Section 9 3 3 2 6 Medical Surveillance Employees working with these substances on a routine basis should consult with The Workplace at 2151 Highland Avenue Birmingham AL Ph 205 933 5300 or with a qualified physician of their choice See Section 7 3 3 Work with Select Agent Toxins Covered under 42 CFR 72 13 14 3 4 3 3 1 In response to concern that illegitimate use of certain infectious agents and toxins could have serious effects on human health and safety the Centers for Disease Control CDC and the Department of Health and Human Services HHS issued laws requiring the registration of facilities using and transferring certain materials Select agents Information about the infectious agents covered under this legislation may be obtained f
177. toluene and acetic acid O8FL Fluoroscein isothiocyanate 14WS Fluorotoluene ortho O8FL Folin amp Ciocalteau s Reagent 03CA Formaldehyde solution 08FL Formalin 08FL Formamide 10TX Formanilide 10TX Formic acid 08FL Formic acid sodium salt 10TX Formvar resin 19NH Formylbenzoic acid 2 10TX Formylbenzoic acid 4 10TX Formylglycine 10TX Freon 22 chlorodifluoromethane 10TX Freon TF 10TX Fructose 1 6 diphosphate disodium salt 19NH Fructose D 19NH Fucshin acid 10TX Fucshin basic 10TX Fuller s earth 19NH Fumaric acid 10TX Fumaric acid disodium salt 10TX Fumaryl chloride 02CB Fumazone O8FL Fuming nitric acid 16NA Furaldehyde 2 O8FL Furan O8FL Furfural Furaldehyde 2 O8FL Furfuryl alcohol O8FL Furfurylamine 2 aminofuran O8FL Furil dioxime 10TX Furoic acid 2 10TX Furosemide lasix 10TX Furyl acrylic acid 10TX Fyrite 7 contains potassium hydroxide 02CB Galactose D 19N H Explosion hazard 105 H ighly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Galacturonic acid D 03CA Gallein 10TX Gallic acid 03CA Gallium nitrate 11TX Gamma globulins 19NH Gammexane lindane 10TX Gasoline O8FL Gastric mucin powder 19N H Gelatin 19N H Genetron 12 gas 07CG Gentamicin 10TX Gentian violet 10TX Geraniol 08FL Germanium IV oxide 11TX Germanium tetrachloride 14WS Ghatti gum 19NH Gibberelic acid 19NH Giemsa stain 10TX Gleocin 10TX Gluconic acid 19NH
178. tylmercaptan tert Butyl phenol Butylphenoxy isopropyl 2 chloroethyl sulfite 2 p tert Butylthiophenol 4 tert Butyn sulfate Butyne 1 4 diol 2 Butyraldehyde Butyramide N Butyric acid Butyric anhydride N Butyrolactone 4 Butyrolactone beta 3 hydroxybutyric acid Butyronitrile Butyryl chloride Cacodylic acid Cacodylic acid sodium salt Cadmium Cadmium acetate Cadmium acetate dihydrate Cadmium bromide Cadmium carbonate Cadmium chloride Explosion hazard H ighly reactive May form unstable peroxides on standing CPC CODE 14WS 14WS OSFL O8FL 10TX 08FL 170X 08FL 170X 10TX 10TX 10TX 10TX 10TX 08FL 08FL 08FL 10TX 10TX 08FL 10TX 08FL 08FL 10TX 10TX 08FL 02CB 10TX 08FL 10TX 09FS 08FL 10TX 03CA 03CA 03CA 08FL 08FL 14WS 10TX 10TX 11TX 10TX 10TX 11TX 11TX 1ITX 79 Appendix D UAB Waste Registry CHEMICAL NAME Cadmium fluoride Cadmium iodide Cadmium nitrate Cadmium oxide Cadmium sulfate Cadmium sulfide Cadmium waste Caffeine Caffeine citrate Caffeine salicylate Calcein Calcium acetate Calcium arsenate solid Calcium carbide Calcium carbonate Calcium chloride Calcium chromate Calcium cyanamide not hydrated Calcium cyanide solid Calcium dichromate Calcium fluoride Calcium gluconate Calcium hydride Calcium hydrochloride Calcium hydroxide Calcium hypochlorite Calcium iodide Calcium iodobehenate Calcium nitrate C
179. unable to comply with state and federal regulations under the Clean Water Act of 1977 Generators of laboratory waste are advised to exercise caution with respect to sink disposal of chemical wastes In general small scale research activities 100 ml or less of certain types of water soluble non toxic and non flammable chemicals may be poured if they have been approved by the Chemical Safety Director It is recommended that such materials be disposed of through the Department of Occupational H ealth and Safety even in small quantities 11 3 4 Substitution Whenever possible it is desirable to substitute non hazardous biodegradable chemicals for hazardous chemicals Use of these chemicals will reduce the volume of hazardous waste generated Examples of acceptable substitutes include 1 Citric Acid based clearing solutions for xylene benzene and toluene containing reagents in histology laboratories 2 Non hazardous liquid scintillation cocktails for standard xylene and toluene based cocktails used in radioactive tracer studies 3 Water based inks instead of solvent based inks in printing operations 4 Non halogenated solvents in parts washers or other solvent processes 5 Detergent and enzymatic cleaners can be substituted for sulfuric acid potassium dichromate chromerge cleaning solutions and ethanol potassium hydroxide cleaning solutions 6 Peracetic acid rather than formaldehyde in cleaning dialysis machin
180. uric acid 03CA Sulfurous acid 03CA Explosion hazard 143 Highly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Sulfurous acid diethyl ester O8FL Sulfurous acid dipotassium salt 11TX Sulfuryl chloride 14WS Superoxide dismutase 19N H Talc 19N H Tannic acid 10TX Tantalum 11TX Tantalum carbide 11TX Tartaric acid 19N H Tartrazine 10TX Taurine 19N H TBTO 11TX Technicon wetting agent 10TX Tedion 10TX Teflon 07CG Tellurium 11TX Tensilon Edrophonium chloride 10TX Terebene 08FL Terephthalic acid 10TX Tergitol 10TX Terphenyl p 10TX Terpineol O8FL Terpineol alpha O8FL Terpinol O8FL Tert butyl hydroquinone 10TX Tert butylchlorodiphenylsilane 02CB Tert butylisothiocyanate 10TX Tert butyl phenol 4 02CB Tert butyl phenol p 10TX Tert butyl pyrocatechol 4 4 tert buty catechol 02CB Tert pentyl alcohol Tert pentanol O8FL Testosterone 10TX Testosterone propionate 10TX Tetraacetic acid N N N N 03CA Tetrabromobenzene 1 2 4 5 10TX Tetrabromoethane 1 1 2 2 O8FL Tetrabromo m cresolsulfonephthalein 3 3 5 5 10TX Tetrabromophenol blue 10TX Tetrabromophenolsulfonephthalein 3 3 5 5 10TX Tetrabutylammonium bromide 10TX Tetrabutylammonium hexafluorophosphate 10TX Tetrabutylammonium hydroxide 40 in MeOH 02CB Tetrabutylammonium iodide 10TX Tetrabutylammonium perchlorate 170X Tetrabutylammonium phosphate O8FL Tetrachlorobenzene 1 2 4 5 10TX Tetrac
181. usssasenssnssanen 159 H HAZARDOUS CHEMICAL INVENTORY FORM n 163 I AUDIT FORMS E S 165 J CHEMICAL HYGIENE PLAN OUTLINE nnn 171 K DESTRUCTION AND DISPOSAL OF ETHIDIUM BROMIDE 177 L MANAGEMENT OF PHOTOGRAPHIC CHEMICALS une 179 M SAFE HANDLING PROCEDURES FOR ADMINISTERING HAZARDOUS DRUGS 0s020u0u0n0n000s020002222010n0000000000000000000010200 0000000000n00 000 181 L INTRODUCTION In a comparatively short time the University of Alabama at Birmingham has gained significant recognition as a center of excellence for teaching medical services and research programs This is a highly commendable achievement and one that could not have been realized without the continued support and dedication of faculty staff members and employees Similar unfailing cooperation and support are necessary for the institution to be equally successful in its develooment of a comprehensive occupational health and safety program for the protection of University personnel students and the surrounding community An important part of this program is concerned with the safe and prudent handling of chemicals and their proper legal disposal as regulated by the Environmental Protection Agency EPA and the Alabama Department of Environmental Management ADEM Almost every laboratory and many allied and support personnel at UAB use chemicals in their daily activities It is the purpose of this
182. ve your name telephone number as well as your building and room number State where you will meet the emergency vehicle State how many persons are involved and the type and severity of any observed injuries Notify others in the area about the nature of the emergency M eet the ambulance or fire crews at the place you indicated in 10 1 above Send someone else if you cannot go Do not move any injured persons unless they are in further danger Keep them warm Unnecessary movement can severely complicate neck injuries and fractures If chemicals have been spilled on someone get the individual under a shower or spigot to wash the affected area thoroughly If chemicals are in the eyes irrigate with plenty of water for at least 15 minutes Check for and remove contact lenses before irrigation however contact lenses may be difficult to remove and the irrigation must not be delayed If hazardous chemicals are ingested try to identify the substances involved Notify medical staff or the local poison control center 4 4606 Never attempt to give anything by mouth to an unconscious person If there is a very small fire extinguish it by smothering with a nonflammable material such as an inverted beaker or using the appropriate fire extinguisher Fight the fire from the position of escape Cut off electrical circuits and gas lines Close fire doors If a person s clothes are on fire douse the individual with water or wrap the perso
183. worn when using an apron Closed front gown Impervious closed front gowns with long sleeves and knit cuffs provide increased protection when working with hazardous drugs or extrenely hazardous chemicals Cuffs must be tucked under gloves Contaminated outer garments should be cleaned or disposed of properly Respirators Engineering control measures and work practices are designed and implemented to eliminate or minimize atmospheric contamination However when contamination exceeds the regulated levels an employee may be required to wear a respirator If a respirator is required the employee must be properly fit tested trained and have a physical examination before use The Department of Occupational Health and Safety will provide this service and should be consulted before any type of respirator is used 35 9 SPILLSAND ACCIDENTS 9 1 9 2 Personal Injury 9 1 1 9 1 2 9 1 3 9 1 4 Eye Contact Promptly flush eyes with water for 15 minutes and seek medical attention Ingestion Call Poison Control 4 4606 and seek medical attention Skin Contact Promptly flush the affected area with water and remove any contaminated clothing Soap may be necessary for non water soluble compounds If symptoms persist after washing seek medical attention Inhalation Move the victim to fresh air If the victim is unconscious or not breathing seek emergency medical attention immediately Death or permanent injury can occur wit
184. xides on standing Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Lithium aluminum hydride 14WS Lithium bis trimethylsilyl amide 14WS Lithium bromide anhydrous 11TX Lithium carbonate 10TX Lithium chloride 11TX Lithium citrate 10TX Lithium dichromate 11TX Lithium fluoride 11TX Lithium hydride 14WS Lithium hydroxide 02CB Lithium hydroxide monohydrate 02CB Lithium lactate 10TX Lithium magnesium 11TX Lithium nitrate 170X Lithium oxalate 11TX Lithium perchlorate trihydrate 170X Lithium pyruvate 10TX Lithium salicylate 10TX Lithium sulfate 11TX Lithium metal 14WS Lithopone 11TX Litmus powder 19N H Lloyd reagent hydrated aluminum silicate 11TX L phosphatidyl choline 19N H L phosphatidyl choline 19N H Lucidril dimethylaminoethyl 4 chlorophenoxy acetate 10TX Luminol 10TX Lupinidine 10TX Lusozyme 19N H Lustran 10TX Lutidine O8FL Luxol fast blue 10TX Lympholite M 19NH Lyphogel 19NH Lysine monohydrochloride L 19NH Lysine L 19NH Machete 10TX Magnesium acetate tetrahydrate 19N H Magnesium bromide 11TX Magnesium carbonate hydroxide pentahydrate 11TX Magnesium chloride 19N H Magnesium fluoride 11TX Magnesium hydroxide 02CB Magnesium nitrate 170X Magnesium nitrate hexahydrate 170X Magnesium nitride 14WS Magnesium oxide 11TX Explosion hazard 115 Highly reactive May form unstable peroxides on standing Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE Magnesium perchlorate 170X Magnesium r
185. y 4 sulfo 1 naphthylazo 3 naphthoic acid 2 Hydroxy 2 naphthoic acid 3 Hydroxy 3 5 dimethoxybenzoic acid 4 Hydroxy 3 methoxybenzoic acid 4 Hydroxy 3 methyl benzoic acid 2 Hydroxy 3 methyl 2 butanone 3 Hydroxy 3 naphthaldehyde 2 Hydroxy 4 methyl 2 pentanone 4 Explosion hazard H ighly reactive May form unstable peroxides on standing CPC CODE 10TX 10TX 19NH 19NH 19N H 19N H 19N H 10TX 10TX 10TX 10TX 10TX 02CB 15SS 10TX 08FL 03CA 10TX 03CA 10TX 03CA 03CA 03CA 08FL 10TX 10TX 03CA 03CA 03CA 07CG 03CA 19N H 15SS 07CG 11TX 10TX 10TX 08FL 10TX 10TX 03CA 03CA 03CA 19NH 10TX 10TX 08FL 109 Appendix D UAB Waste Registry CHEMICAL NAME CPC CODE H ydroxy 5 sulfophenyl 3 phenyl 5 formazano benzoic acid 2 10TX H ydroxy 7 iodo 5 quinolenesulfonic acid 8 03CA Hydroxyacetic acid 03CA Hydroxyacetophenone 3 10TX Hydroxyadipaldehyde 2 10TX Hydroxyapatite 19NH Hydroxyazobenzenbenzonic acid 2 4 10TX H ydroxybenzaldehyde 4 10TX H ydroxybenzene O8FL H ydroxybenzene sulfonamide N 10TX H ydroxybenzeneacetic acid 2 10TX H ydroxybenzoic acid 10TX Hydroxybenzoic acid phenyl ester 2 10TX H ydroxybenzotriazole hydrate 10TX Hydroxybutyric acid 4 sodium salt 10TX Hydroxycoumarin 7 10TX Hydroxydiphenyl p 10TX Hydroxydiphenylamine 3 10TX Hydroxyethyl disulfide 2 10TX Hydroxyethyl ether 2 O8FL Hydroxyethyl methacrylate 2 10TX Hydroxyethyl morpholine N
186. zard by Concentration As the ratio of product to peroxide concentration decreases the hazard due to the peroxide increases Acetal Decahydronaphthalene Decalin Diacetylene Dicyclopentadiene Tetralin Diethylene glycol dimethyl ether Diglyme Dimethyl ether Ethylene glycol Tetrahydronaphthalene Hazardous Due to Peroxide Initiation of Polymerization 61 Appendix B Highly Reactive Compounds Acrylic acid Chloroprene Methyl acetylene Methyl methacrylate Styrene diacetylene Vinyl acetate Vinyl pyridine Other highly reactive compounds 62 Compounds Containing the Following in their Nameor Formula Acetylide Azide Bromate Chlorate Chlorite Diazo Halamine lodate Nitrate Ozonide Perchlorate C C NN N BrO3 CIOs ClO2 N N X NH3 X is any Halogen e g Cl Br I F 103 NO3 Os CIO4 Appendix C Chemical Packing Codes CHEMICAL WASTE REGISTRY The Chemical Packing Code CPC characterizes the primary hazard associated with each material The first two digits of the CPC are designed to distinguish which materials can be packed together When packaging materials for disposal each box must indude only materials within one packing code 00 CORROSIVE BASES CB Bases packed together and separate from acids 03 CORROSIVE ACIDS CA Inorganic acids including halo organic acids and organic acids acid anhydrides and acid chlorides packed together and away from oxidants 07

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