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Software Manual for Acquisition and Processing of SPECT images

1. Select mode there are three options available in the drop down menu Single Reconstruction Batch Processing and ColorSPECT Each of these options will be described in detail in their corresponding section of this chapter Single Reconstruction Single Reconstruction is the simplest reconstruction option in FLEX SPECT Once Single Reconstruction has been selected the screen shown in Figure 2 4 2 will appear 47 TRIUMPH X SPECT USERS MANUAL y E at 3 q apa gt p A TE is FLEX SPECT Reconstruction GAMMA MEDICA IDEAS gt Please choose your files and parameters below and click Reconetruct Circolaa Solari any one of ther acquired interiiies CT Daai CIO Oplimicmtion Data fateiesja21961733 HDA o Edy Me Hi Line Saureeft Tm Exch Daffie Dec 18 HOR MERA Focallength me 30 Num Projecttanafiagies 17 J 180 CEW Celima icin Mimiale fire iam 1 Tihmefpijecian ieee 15 00 Save Retell Me aai fchooue aa a Img We Bell C10 Optimization Dub HOR fmm E efector mode Dual Mumbrer ef erations 5 Alcconsirurt Exit Figure 2 4 2 Single Reconstruction mode First select an Interfile to be reconstructed Interfiles are a standard nuclear medicine file format for image data that consist of two separate files for each data set one is a header file Adr containing information about the data set and the other is the image data 7mg in a binary data format Interfiles can be either acquired tomography data or
2. system Single for one gamma camera and Dual for two gamma cameras However there are situations in which the user might need to change the detector mode e g if one gamma camera is currently unavailable then a single head reconstruction may be necessary e GDRC is an option to enhance the physics of the reconstruction and is discussed in more detail later in this chapter e The Number of Iterations and Number of Subsets fields relate to the nature of the iterative reconstruction algorithm used in FLEX SPECT FLEX SPECT uses an Ordered Subset Expectation Maximization OSEM iterative reconstruction algorithm for its pinhole reconstructions o Number of Iterations controls the number of full iterations full in this sense means the complete set of projections are used used before the OSEM is stopped This number can be as small as and as large as the user desires though the time of reconstruction is proportional to the number of iterations and so large values 1 e greater than 10 are not recommended o Number of Subsets controls the number of projection subsets used as updates in the reconstruction for each iteration of forward projection back projection The Number of Subsets therefore must divide evenly into the number of projections for the given study As the number of projections 1s a multiple of 16 e g 32 64 and 128 the possible values of the Number of Subsets are 2 4 8 and 16 G
3. Triumph SPECT Calibrations GAMMA MEDICADEAS j Gantsy Cabbrarion UET Qc Sowce Isotope Tay hotape isotope Nome liotope Name Cos F nmyp Window OPEN Tracy Window 203 Energy Window 203 Source and target Add Remove Clea Camera Status Source trotope N Source trotepe Energy Target Isotope Name Target isotope Ene Te 33m 20 Co 57 20 Progress window Start Stop Close Figure 2 2 12 UCT window e Source and Target This is the essence of the UCT window It defines all the identifiers of the correction table Collimator the drop down list of this input field contains exactly the same list of collimators as for the protocol window Source Isotope the isotope that will be used to acquire the flood image The Energy window drop down list is unique to the selected isotope and can not be left blank Target Isotope the additional isotope and energy window that this UCT could be used This input field can not be repetitive of the source isotope for the source isotope has already been included and is not additional Action Buttons for adding removing target isotopes and for clearing the entire isotope list Isotope list all target isotopes this UCT will be calculated for the source will be listed by default plus any added target isotopes e Acquisition info This session assures the quality of the flood images in order to obtain a good UCT 15 TRIUMPH X SPECTO USERS MANUAL Total c
4. all the heads you want to use then click OK NOTE This is the only time the progam asks for camera settings should user decided to change camera heading e g active the second head the only way is to exit and restart Triumph_SPECT There is no need to re establishe the telnet connection for this purpose In a few seconds the Triumph SPECTTM will open by default Scan window will be presented to you If you have already established your studies and protocols for your experiment please go ahead to open and scan window section If this is the first time you use your machine please take some time to build your protocol and study libraries To Set up a Scan y Build or modify a Study To build a study click the set up icon on the top menu bar of the software and the set up window will replace the default window with study tab at the front The Add button at the bottom indicates that this is the time for you to generate a new study Triumph SPECT Set Up GAMMA MEDICA DEAS gt Esclirg Study Liat Potent Inmomatron Study Protocol Study Nama Description Stanly Name Patieet Name Ses Male GEULAL SUPE RPHAMN TUM invnstigatos Operator Woight qm boo 924 2008 v Shady Desenphon Description Add Patiesi Shady History Patent Nane Protocol Name 5cen 10 5can Mode Scan lane Scan Desorption View Edil Delete Add Close Figure 2 3 5 the original study window 29
5. button and the new reconstruction will be added to the batch list as shown in Figure 2 4 8 Displayed in the Batch Processing screen are the Study a sequential number identifying the particular batch job the Study ID the Detector mode a Progress and a Status column The Progress column specifies the current state of the batch job Possible values for this column are given in the table below The Status column specifies the final state of the batch job Its possible values also given in the table below Progress Status Description Study added and ready to be reconstructed Study currently being reconstructed Study finished reconstruction Reconstruction finished with no errors Reconstruction failed 538 TRIUMPH X SPECTO USERS MANUAL Possible values of the Progress Status column in the Batch Processing screen When all the studies have been added to the Batch Processing screen the reconstruction can be started by clicking on the Reconstruct button When the batch process is running a progress bar appears at the bottom of the screen and the progress of individual studies can be tracked in the Progress column When all of the batch reconstructions are complete an additional button labeled View Report will appear to the right Upon clicking this button a report of warnings and or errors will be displayed If no warnings and or errors exist for a given study the report will simply read No Errors If a
6. EOTS ito See Troubleshooting EX DOM E E T A A E P A P A E E A T ueceens 17 EXpOning SPECT d la eretta aaraa aapa Aara toa 21 F FIET nacen a E E a Gaus 13 17 FOV se acueidwaddncvannad undevecancoaas atandaesavnetaunacedvaniesatoedauz 9 co 9119 PL y PCR N EA A tic Seca E ca san S E E E E E S 36 Gated cardiac image analysis ici 62 Gated image reconstrUcHoON siise aeaa iaaa Naaa silla 58 Generale Special as 48 Geometric detector correction response GDRC oonccccccccccononccconcncccnnnnnnonananonnnannnnnnncnenanannos 32 H FearibeatQuUratON cansino lirica bvecsndesvadsanesnadeedscsadsetineaiecdenbaeredecs 56 A lee ee ae ee ee eee See Thermal regulation Ayo tema ca ete aces sh ete eee ees See Thermal regulation I NStalatON ora 67 TAKE a E callada 44 46 74 O O 71 El A O E en 44 46 L EMPLOI 44 69 77 L maGE M Pesce ste eee cactus eo a A ah nate aa A a tea aie 42 52 BUTT rr re CC 1 dl Pos A ad 57 IV aS cress rada al aid 19 63 New Paletas Aa 5 7 8 52 P Parallel colimatoi S iii A A ae necet 11 78 TRIUMPH X SPECTO USERS MANUAL Parameter MES ia 68 70 PatlentintoOr Ma ION cas 52 o AAA aa ccovassensenseeseeecetsaniees 20 64 Prep SPECTRA 58 Processing Dynamic SPEC T POCOS ai lab 13 Slalic Or EG T PIOCESSING A di 12 Tomographic SPECT Process li iva 16 Projecto report cca tod 20 Quality control OG iii 26 GATTI ATION ios 66 R Reorientand 200 Msn 19 62 A AP E T A cea ae ates E E E E E E sana aac taut Gede
7. TOS CRUD aC ie 21 Build ormodify a Stud dis ates ke 21 B ild a PELOTCOCO sta o A il beens 24 Bulld a Protocol Using Protocol Builder sad 25 TO Petrtormia scam Tomo gra DALE iaa ii 26 Open the Scan WINGOW ein 26 Position theanimal DY NANG surtidas 28 Start the Sacn Automatic and affine positi0NiNgQ ococccccconcnonononcnnononononancnnononancncnnonnnnnancnnanono 29 To perform other type Of SCAN cccccccccocnconccnnncnnnnnnnnnncnnncnnnonnnannnannss 32 Stat OCN Pol 32 Dyna mic SEAN a o iaa 33 Tomographic Spiral Scans td a do 33 Dynamic POMC SCAN ri adas 34 Gardiacror Respiratory Gated Scala id ds 35 A ae ne RE te Soe DEE ORT ne ne On en ToT ne Re 35 Data VIS Wind AS OA 35 Datadimportana EXPO bus e cios 37 Service and Maintenance CalibratiON oooococccncncnncnnnnnnnannnnanannnos 38 Garey ae Som a CONIL eT eare 38 Gantry CaliDFac OM en uso botnets laces use dere lla c nds 38 Camera Calibration UCT and QC aaa iia ta 39 Uniform Sources for UCT Cambra As 39 Procedure for U ET Calor ON ri A AA 40 Error Messages and TroubleshootingQ ccoccccoccccnnconnncnnncannncnnncannos 41 Gantry CONNECUON ETOT a cas 42 Program CONnecton FOR tri adas 42 Warning upon an eXItInga actions 42 Warning TO rms sind informatio cs senrima Ai 43 Warning Or MOdITCaciON ars loco 43 Contirmatio son exiting acond 44 PTOCES SINO EFO keneen E acne ec kcamaeenace bite aa aoa T ante e cua E T AES 44 Gantry perrornmalce Erotic dns 44 Data Manage
8. Tomographic Open the Scan Window 7 After all the studies and protocols are built you are ready to start a scan Triumph SPECT Scan GAMMA MEDICAJDEAS T Animal Status Caria Status Siudy pm wa Hew Poenutercs image TZ w F Wiraka Patent z New E k a PHT UCT Mene Frotnoni re Full Aity ia Inector Tira Pump I Details banliy Slatur Scan Progen Hed onion e Gantry jungle YH EH HOH pmm Oo O Save List Mode Chore Figure 2 3 12 Default Scan Window To start a scan click the Scan icon and go into the scan window In the left panel from top to bottom please select the study patient and protocol you 26 TRIUMPH X SPECTO USERS MANUAL would like for your scan In this section the most common scan a cicular tomographic scan will be used To start the scan click on the scan icon to the top menu bar and the default scan window should be presented After selection the detail button will be activated and upon clicking you can review all the important features of that particular study patient and protocol Tools EE Resolution test Study Properties MA MEDICA Study Name Resolution test INNOVATION FOR L Operator Joann Description Resolution measurement at close radius of all coll Study Resolution test v Details New pe y Details Creation Date 9 24 2008 8 11 46 PM 3 E Wind Patient Super Phantom v Details New
9. indicator in the persistent window e Count Rate Real time count rate display of all camera head cps stands for counts per second Lines are color coded similary e Information Panel Detail gantry status window during a scan all input fields are disabled and for observation purpose only before a scan this panel can be used as a protocol builder which will be introduced in a later section 12 Information TRIUMPH X SPECTO USERS MANUAL Data Viewer Window ae A Data viewer window will show up after user selected interested image from the data list The viewer window contains the following panels Triumph SPECT Data Viewer Z A r E e Figure 2 2 9 Data Viewer Window No of Projectons Per image 64 Time per Projection 15 secs v GAMMA MEDICA DEAS DD Shady Parameters 1 V24 2008 350 02 Pw Tc Vim 1125 140 154 e Viewer screen The top window in the left panel continuously run through acquired projections with a chosen camera head The play control under the screen can stop run pause or adjust running speed of the movie The bottom screen shows the sinogram of a selected plane through out all the projections the plane can be selected by dragging a white line up and down the projection window Figure 2 2 10 Projection and sinogram ice TRIUMPH X SPECTO USERS MANUAL e Setting control CameiaHead 1 v hope ToS V Eneida 20 v These drop down list allow user to choose wh
10. l CPU priority flag higher number means LMPro ini The LMPro ini parameter file controls the operation of ColorSPECT Short descriptions of the parameters and their possible values are given in the table below Default Default_Angle 180 360 The gantry rotation angle Default_Collimator 5B10 Collimator name Default_Isotope TC 99m 20 Isotope and enay window 65 TRIUMPH X SPECTO USERS MANUAL Default_PatientName Patient Name Patient Name Default_Protocol Sos Tomo Protocol Static or Tomo Type of spectrum file to generate summed over all pixels or individual pixel ectra spectra Study Name Study Name Minimum yea in spectra Generate UCT flag O false 1 true LumaGEM_Path valid path D LumaGEM LumaGEM base path 1 true y O false 1 true oT Highest time stamp to consider timeWinLow Hener Lowest time stamp to consider 9 ms O consider all Summed Individual Summed Default_Spectrum Parameter Files Il ColorsPECT Files The files shown in the table below are necessary for the proper operation of ColorSPECT Camera File e D LumaGEM acacnt ini Acquisition configuration file ee l List of available isotLUM dir D LumaGEM Acauisition isotLUM dir isotope energy windows collimators dir D LumaGEM Acquisition collimators dir List of available collimators CalReference ini D LumaGEM Acaquisition CalReference ini Calibration reference file LUT_ bin D LumaGEM Calibrations LUT_ bin Look Up T
11. set the ROR FOV will automatically determined based on the set ROR bed position and even gantry angle to better f1t the protocol If you realize that the ROR you set for the protocol was unreal use hand controller to move to a satisfying ROR and check the toggle box by the Use the current ROR text 30 TRIUMPH X SPECTO USERS MANUAL If you wish to modify yet again the protocol click the Set Parameters button at the bottom the parameter window will pop up allowing you to change OK or reset to original Reset Acquisition Parameters Dynamic Tomo Acquisition Parameters Dynamic Tomo Settings Rotation Angle ENI Y Num of Proj 64 Time per Proj sec 19 Num of Scans gt 1 5 Figure 2 3 20 Change parameters in the camera detail window After setting all the parameters close the camera detail window will bring users back to the step 2 message window This time click Done The Scan will officially start The gantry will first position the gamma cameras to the pre defined ROR then rewind to pre defined starting position Then the scan will start During scanning user can monitoring the progress by the following marks on the scan window The Progress bar The information window usally summarizing after each projection The estimated time passed and time left The persistent window Animal status please reference chapter 2 for more details MOODS NOTE Circulated with red circle in
12. to abort the batch job and change the result filenames Confirm Do There s a time window between 0 millisecond s and 1000 milliseconds set in the configuration file wy Are vou sure you want to continue the processing with this window The confirmation message above is displayed when there is a time window set in the LMPro ini file The time window may be disabled by setting both of the LMPro ini parameters timeWinHigh and timeWinHigh to 0 The error above is displayed when the matrix sizes are inconsistent between the two files Please contact GM I customer support if this error occurs 73 TRIUMPH X SPECTO USERS MANUAL Warning 2 The Filename mentioned For saving the projection data already exists Do you wish bo overwrite The warning above is displayed when the filename to be generated already exists UCT Warning Do UCT CLumagem Calibrationsi U COLL SBLOJ IIN 111 3win not found se Do you still want to continue The warning above is displayed when the UCT is not found for the particular collimator 1sotope energy window combination User Error The error above is displayed when a ColorSPECT process has been started but neither a projection Interfile nor reconstruction has been selected Please disable Do reconstruction ES The reconstruction software doesn t support static acquisitions The error above is displayed when the user tries to perform a reconstruction with static
13. 66 Being as specific as possible please enter the Study name operator and a short description of the study In the example shown below a standard scan to determine the system spacial resolution is established 21 TRIUMPH X SPECTO USERS MANUAL Mud Protocol Exicling Study Lin Harbin Int lmmentgalor Opera Pan Revelylon merrucrmenal al chuire rodea of al colmo Siudy Hame Desenpion Suda Hama COOCAL SUT AAT Ok Siudy Durcnplion ud lisboa Patent Hame Dupa Pare 4 i F View seat Delete Pirtocol Hama Scan Mh BTA A A LE Patent Infomation Potter Hama haw Unknown sr Supe Phanlom We cogi qm 5 DOA 42000 Deaton bk cin pinto 0 Sete Ae omankin inla Add Pabani Scan Mode Scan Vena View Sear Figure 2 3 6 A study ready to Ada The study window usually 1s not complete without a patient established since an experiment without a mouse or rat could not be done Therefore a patient set up window is co resided in the study set up window Do your best to fill in all the information as complete and possible for future reference for suggestions please reference the feature introduction in the previous chapter Upon finish click the Add Patient button the patient will show up in the Study History window Upon finish of all the inputs of study and patient click the Add button at the very bottom of the screen the study will show up in the left w
14. X SPECT USERS MANUAL GeomEffc_synap AttenCorr Pinhole sensitivity cosine power term for multi pinhole collimators E S E Attenuation correction currently not used printinfo Print debug info during reconstruction DataFrom AA Debug parameter in reconstruction nblterations e Number of OSEM iterations Savelntv integer Number of save iterations only works if i verbose turned on nbSubsets 1 2 4 8 16 Number of OSEM subsets interpFlag MA GeoCal interpolation scheme Collimator match flag 0 requires exact collMatchFlag collimator match 1 requires only 1 two collimator characters match GeoCal orbit model for single pinhole EIBMOdS OrbitMode_single MPa NS collimators with circular orbit OrbitMode a A B C J GeoCal orbit model for multi pinhole collimators with circular orbit GeoCal orbit model for single pinhole noes OrbitMode spiral es NS collimators with spiral orbit OrbitMode_synap_s GeoCal orbit model for multi pinhole A B C J piral collimators with spiral orbit ane Suna ear Reconstructed matrix size for single pinhole p y2_8yNap g collimators Reconstructed matrix size for multi pinhole HO ALumaGEM l GeocalPath valid En ECN Path to GeoCal files verbose Verbose O disable 1 enable verbose enabled generates par and dat files geo sR m mm aaa detector 12 2 Number of gamma cameras deta gure 01 0 Default GDRC enabledisabie ence ar o Sateen terre ColorSPECT enable disable
15. acquired 3 Gating Mode For Static and standard tomographic imaging Triumph hardware has implemented mechanism for projection images to be parsed based on cardiac and or respiratory rhythm 1 e gated Current release of Triumph SPECT and FLEX SPECT however have not implemented the handling of gated data Therefore in this release of user manual gating mode section will not be discussed and user 1s to always choose none in this section 4 ROR Radius or Rotation ROR is the distance from the surface of the collimator to the center of rotation of the gantry For pinhole collimators ROR decide object magnification geometry calibration reference field of view and final reconstructed image size Therefore an ROR for a scan is very important In terms of a protocol however ROR does not need to be fixed and linked to any other parameters and under many practices turns out to be the ONLY parameter that needs change in the protocol Therefore the protocol set up window placed the ROR setting in an independent window The white input field allows user to set ROR in mm for the protocol while the grey field indicate the current ROR the gamma cameras are positioned FOV stands for field of view which is automatically calculated based on input ROR and should not be edited by users 5 Scan Mode Setting Scan mode setting is a subset or a continuous setting window for scan mode It defines the detail scan parameters of the part
16. allows more counts to be recorded yet it risks cross talking should another isotope is getting co imaged Since Triumph CZT cameras has a very sharp energy resolution 4 at 140Kev users are recommended to choose as narrow of a window as possible Isotopes can be added edited and removed from the list Scan Window 7 Scan window has three main panels Scan condition panel animal status window and camera status window Triumph SPECT Scan GAMMA MEDICA DEAS Je INNOVA TI FOR LIFE Camera Stabur Permitence image F negy Window UCT None Animal Status BedPorten Gantry Angle AOR am Save List Mode Figure 2 2 6 Scan Window TRIUMPH X SPECTO USERS MANUAL Scan Info The main identifiers or determinants of the scan are the top three inputs Study Patient Protocol Therefor all there are mandatory fields to be filled in order to start a scan Each inputs has a drop down list PB a review button which will be activated once an item 1s chosen from the list and a button for users to start one on the fly or ee The builder refers to protocol builder which will be introduced in the next section to perform a scan Patient position choices are prone animal is faced down on the bed Or supine animal is laid facing up for image orientation reference Organs the targeted organ of the image acquisition Although in animal imaging there are usually multiple in
17. click the right buttons on the hand controller please reference the operater s manual for detail By moving the bed in and out up and down left and right try your best to position the target of interest and the laser center Then click next in the message window Skip or Next step 2 will be presented Triumph Please click on the camera details button and set the ROR to the defined value and verify the animal position Rotate the gantry using hand controller to ensure there is no collision at any angle Click Done to start the scan Or click on the Back button to go back to the previous screen Figure 2 3 18 Scan step 2 refine the ROR If you have positioned your camera and you are sure that the ROR matches your protocol click Done directly Otherwise click Camera Details The camera detail window will be presented showing persistant images of all activated cameras Camera Stas Triumph SPECT Camera Status GAMMA MEDICA IDEAS 3 MARIANAS FE EFE Lamera 1 Latecra 3 Energy porri UCT Tc 99m_MEFISA1D Inotopes ahii r ai lidtiph Tc w Energy Window 2U ka Baniy Bettina Callimators ROR fein 40 000 40 003 O en cumnent ROA i 14 toca Pov eins 52 00 5 A PMeritilence Tenor C mera 2 Camera 4 Last Roto UCTATc 74m_HSPFSAio Set ROR igi Bed Povtlion 23040 Set Bed Posltlan Garntry Angle Py Figure 2 3 19 Camera Detail Window In this window
18. collimator change gantry positioning e Data viewer Data viewer window provide explore window for data base management and projection data viewing window TRIUMPH X SPECTO USERS MANUAL e Protocol Builder Protocol builder window is an interactive version of the protocol set up procedure it provide persistent camera windows linked to protocol setting function boxes for facilitate protocol establishment PLEX SPECT e Single Reconstruction Provide standard 3D OSEM reconstruction interface of a single image data e Batch Reconstruction Provide multiple input fields for imaging data to allow reconstruction performed on one set of data e ColorsPECT ColorSPECT provides list mode parsing functionality 1t was wide used for dual isotope image prior to the release of Triumph SPECT While multiple isotope processing has been implemented into the Triumph SPECT and no longer needs ColorSsPECT ColorSPECT can still be used to reprocess flood data for UCT regeneration TRIUMPH X SPECTO USERS MANUAL Chapter Features of Triumph SPECT o switch the mouse and keyboard control from the CT monitor to the SPECT monitor hit the Scroll Lock key on the keyboard twice and then hit enter make sure that the mouse was not moving while switching Set Up Window SY Set up window contains two tabs Study and Protocol It is activated by clicking on the set up icon on the top menu bar Study Study window contai
19. displays any pertinent information about the process and will alert the user when processing 1s complete Upon exiting FLEX SPECT from ColorSPECT a window will open prompting the user to save the ColorSPECT configuration file which saves the last ColorSPECT settings used by the user to the LMPro ini file For more information on parameter files please reference the appendix of this chapter Tomo Protocol ColorSPECT s tomo protocol is very similar to the static protocol described in the previous section but a few additional fields need be filled out As in the static protocol first select the list mode file to be processed by clicking on the browse button of the Choose Color SPECT File field A dialog box will appear in which the user can search for the desired list mode data The tomo list mode files are in the same Savelistmode directory and should be selected in the similar way as for the static files except that only one projection file need to be selected the program will identify the rest PA FLEX SPECT Version 1 0 6 ala S p Th A A FLEX SPECT Reconstruction menica ipeas gt Please select the color SPECT study and click Process Selea mode Color SPECT Color SPECT Pile Information Choose Color SPECT File SPECT Data Ci Optimization Dala LHlbbatalTomo_13_29 49 _000 bin aa Study Hame LineSourceH Jimm Patiem Name System Testa Patient ID 0001 Inotope Tom zie Colimat
20. ibs eae UCT Tc 99m_N5F75A10_ 20 a Protocol Close Range High Sens MA EE Super Phantom Patient Propeties ES emperature d Patient Name Super Phantom Patient Position B 54 Weight 05 Organ a Sex Unknown q Date of Birth 9 24 2008 8 06 14 PM Activity Administration Description GMI custom phantom 0 5mm 1 2mm resolution grids Isotope Activity mci jection Time Pump I JoinDate 9 24 2008 8 12 39 PM EE Close Range High Sens Protocol Propeties Protocol Name Close Range High Sens N5F75410 Collimator E Protocol ScanMode Tomo 48 60 Protocol Description close radius acquisition with multipinhole collima Time sec None 0 0 0 Gating Mode Gating Bins Lower Gating Window in 2 Op Higher Gating Window in 3 i feces Create Date 9 24 2008 8 31 28 PM De ROR in mm 35 25 048 Modality Code NM 354 394 Isotope Tc 99m 35 000 20 in ke 126 140 154 1 64 Number Of Scans Number OF Projections Rotation Angle in degree Start Angle in degree Time Per Projections in secs Figure 2 3 14 Details overview of Study Patient and Protocol in the scan window Although not encouraged it is possible to generate a new study a new patient for this study or a brand new protocol on the spot By clicke the new button or the Builder button related s
21. protocol 74 TRIUMPH X SPECTO USERS MANUAL Warning 4 UCT For this isotope already exists Do you want to overwrite the existing UCT The warning above is displayed when the user is creating a UCT in ColorSPECT and a previous UCT with the same collimator isotope energy window already exists It is not recommended to overwrite pre existing UCTs without first backing them up Customer Support If technical assistance or support 1s needed please contact the Gamma Medica Technical Service Department by phone at 818 709 2468 or through GM Ps web site at www gammamedica com General Warranty SELLER WARRANTS ITS PRODUCTS AGAINST DEFECTS IN MATERIAL AND WORKMANSHIP IN NORMAL USE FOR THE PERIOD OF ONE 1 YEAR THIS ONE YEAR PERIOD BEGINS ON THE DAY OF INSTALLATION OR THIRTY 30 DAYS AFTER DELIVERY TO THE PLACE OF INSTALLATION WHICHEVER IS EARLIER THIS WARRANTY IS IN LIEU OF ANY AND ALL OTHER WARRANTIES OTHER THAN TITLE ARISING BY STATUTE OR OTHERWISE IN LAW OR FROM A COURSE OF DEALING OR USAGE OF TRADE OR OTHERWISE INCLUDING BUT NOT LIMITED TO WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE SELLER S LIABILITY FOR ANY CLAIM OF ANY KIND INCLUDING WITHOUT LIMITATION NEGLIGENCE FOR ANY LOSS OR DAMAGE ARISING OUT OF CONNECTED WITH OR RESULTING FROM ANY SALE OR FROM THE PERFORMANCE OR BREACH OF A SALES CONTRACT OR FROM THE DESIGN MANUFACTURE SALE DELIVERY RESALE INSTALLATION TECHNICAL
22. reduced spect Notepad XP or NT operating system 1 GHz CPU or faster 1 Gbyte or more of RAM 15 monitor or larger resolution 1024x768 or larger 1 Gbyte or more of free disk space File Edit Format View Help orbitmode_synap B performance on systems that fail to meet these orbitmade spiral o EN TM orbitmode_synap_spiral B minimum requirements To install FLEX phanxyz_synap 50 p pharnoyz_s1ng SPECT follow these steps maxextrapolation mm 5 default_detector 2 Copy the folder FLEX SPECT from the supplied installation CD to Mortal the C Program Files directory Open the folder C Program Files FLEX SPECT and make a shortcut to the Figure 2 6 1 The spect ini file executable FLEX SPECT exe on the desktop for easy access Open the file C Program Files FLEX SPECT spect ini with a text editor such as Microsoft Notepad In the GeocalPath parameter enter the local LumaGEM Pinhole path typically this will be D LumaGEM Pinhole as shown in Figure 2 6 1 To enable disable 63 TRIUMPH X SPECTO USERS MANUAL ColorSPECT set the Color_SPECT parameter to 1 enable or 0 disable Typically if the list mode data resides on the installation computer ColorSPECT should be enabled if not ColorSPECT should be disabled FE LMPro Notepad e If ColorSPECT is enabled open the file pfs Ea C Program Files FLEX SPECT LMPro ini oefault collimator 1c10 with a text ed
23. the image the total counts acquired in each projetion is shown after each projection is acquired 31 TRIUMPH X SPECTO USERS MANUAL Triumph SPECT Scan Triumph SPECT Scan GAMMA MEDICA IDEAS eS INIA NON FOA LIF Cameo Status Study Deta r Ponmitence image I e Pabent Details Easy Weeden 20 s ca UCT Te Same NSFISALO 20 Protocol Detaite m lt gt f Dotai Uperatos Gantry Stetus Description BedPunben 23 043 Gantry Angle 16 007 ROR fam 40 000 Projection 84 of Es peogecton is bemg acquered A m Slop Tame C lapsed 00011 C st Remaining Time 00 22 22 Figure 2 3 21 Scan in process To perform other type of scan Static Scan Static scan is an acqusition of a 2D gamma image To performe a static scan simply build a protocol with the static selected in the scan mode section then fill in the needed setting parameter in the bottom window Static Settings Acquisition Time sec Acquisition Counts Kilo Add Figure 2 3 22 Static scan settings When perform the scan choose the static protocol Animal positioning and scan manual operation are the same as for the tomo scan lt 3 TRIUMPH X SPECTO USERS MANUAL Dynamic Scan Dynamic Static scan is an acquisition of a series of 2D gamma images for a pre set time point and time span To perform a dynamic static scan build a protocol with the Dynamic selected in the scan mode section then fill in the needed set
24. will become active as shown in Figure 2 4 7 1n most cases only one of these fields needs to be filled out Enter the value of Spiral step size mm that was used in the acquisition 1 e the same number Az that was used in the gantry ini file to acquire the tomo dataset along with the sign to ensure proper translation direction The Begin reconstruction at Interfile and No of interfiles to be considered fields may be modified for the uses listed below but in most cases their default values should be adequate e Begin reconstruction at Interfile is an optional field that allows the user to discard any number of the first orbits e g if this field is set to 2 the first orbit will be discarded in the reconstruction The default value of this field is 1 1 e to start with the first orbit available e No of interfiles to be considered is an optional field that allows the user to limit the spiral reconstruction to a smaller subset of the total number of orbits acquired e g if the number of orbits in a spiral acquisition is Norbits 4 and this field is set to 3 the last orbit will be discarded in the reconstruction The default value of this field is ALU i e to consider all available orbits in the reconstruction Fill out the remaining fields as described under the Single Reconstruction section of this chapter Spiral reconstructions work in both single and dual detector mode and
25. 77 426 2633 FLEX X SPECT The error above is displayed when the user tries to start FLEX SPECT multiple times Only one FLEX SPECT application may run at any time on a given computer Warning Do you wish bo overwrite 2 The Filename mentioned For saving the reconstructed data already exists us This warning above is displayed if the user tries to create a result file that already exists The user may overwrite the file Yes or abort the action and rename the result file No 69 TRIUMPH X SPECTO USERS MANUAL The error above is displayed when a non tomographic e g static or dynamic Interfile is selected for the reconstruction Only tomographic Interfiles may be reconstructed The error above is displayed when an Interfile acquired in a CW direction is chosen for reconstruction as only CCW orbits are allowed Please contact GM I customer support if this error occurs Parameter Error The error above is displayed when the GeoCal files are not found in the designated calibration path Check the spect ini file to ensure that the parameter GeocalPath is set to a valid path that contains GeoCal files Parameter Error XX The given Focallength the number of pinholes and the detector number doesn t match any of the calibrations May be due to collMatchFlag in C test PLEX XSPECT Recon 1 0 5 spect ini 70 TRIUMPH X SPECTO USERS MANUAL The error above is displayed when GeoCal file
26. 9 030 E Tomo_13_29 49 031 E Tomo_13_29 49 032 E Tomo_13_29 49 033 E Tomo_13_29 49 034 E Tomo_13_29 49 035 E Tomo_13_29 49 036 the base name for the list My Computer mode data stored as bin ES e A File name Tomo_1 3 29 49 000 bi files The highlighted file ay aa Tomo_13_29_49_000 bin tee RRE is an example of tomo list mode data in which each individual projection is stored with the base name Tomo_13_29 49 with the projection number counting from zero appended onto this base name For example Tomo_13 29 49 000 bin and Tomo_13 29 49 00lI bin are the first two projections of the Tomo_13_29_ 49 acquisition The number in the tomo base name refers to the start ttme of the first projection in an hours minutes seconds format based on a 24 hour clock If 32 projections were acquired over a 180 gantry rotation then 32 tomo list mode files would be generated Each tomo file contains list mode data from one or two gamma cameras The user only needs to select one of the tomo list mode files it does not matter which projection is selected and the remaining files will be automatically detected Files of type Figure 2 4 12 Dialog box showing static and tomo list mode data in the D LumaGEM LMData folder Once the list mode data has been selected a new Study Name Patient Name and Patient ID must be entered in order to populate the new static Interfile that is to be generated It is a good prac
27. DIRECTION OF INSTALLATION INSPECTION 75 TRIUMPH X SPECTO USERS MANUAL REPAIR OPERATION OR USE OF ANY EQUIPMENT COVERED BY OR FURNISHED UNDER A SALES ORDER SHALL IN NO CASE EXCEED THE PRICE ALLOCABLE TO THE EQUIPMENT OR UNIT THEREOF WHICH GIVES RISE TO THE CLAIM NOR SHALL ANY LIABILITY OF ANY KIND EXTEND OR ARISE BEYOND FOUR 4 YEARS FOLLOWING THE COMPLETION OF INSTALLATION OF THE EQUIPMENT NOR SHALL SELLER BE LIABLE TO THE MAXIMUM EXTENT PERMITTED BY LAW WHETHER AS A RESULT OF BREACH OF CONTRACT OR TORT OR WARRANTY OR ALLEGED NEGLIGENCE OR OTHERWISE FOR INCIDENTAL SPECIAL EXEMPLARY CONSEQUENTIAL OR OTHER SIMILAR DAMAGES INCLUDING BUT NOT LIMITED TO LOSS OF PROFITS OR REVENUE BUSINESS INTERRUPTION LOSS OF USE OF THE EQUIPMENT OR ANY ASSOCIATED EQUIPMENT COST OF CAPITAL COST OF SUBSTITUTE EQUIPMENT FACILITIES OR SERVICES DOWN TIME COSTS OR CLAIMS OF CUSTOMERS OF THE PURCHASER OR THIRD PARTIES FOR DAMAGES EVEN IF SELLER HAS BEEN ADVISED OF THE POSSIBILITY OF THOSE DAMAGES OR THEY ARE FORESEEABLE SELLERS LIABILITY IS FURTHER EXPRESSLY CONDITIONED UPON COMPANY RECOMMENDED MAINTENANCE PRACTICES AND OPERATING LIMITATIONS BEING ADHERED TO AND PERFORMED ON THE PRODUCTS WITHOUT LIMITING THE FOREGOING IT IS EXPRESSLY UNDERSTOOD AND AGREED THAT EACH AND EVERY PROVISION OF THIS DOCUMENT THAT PROVIDES FOR A LIMITATION OF LIABILITY DISCLAIMER OF WARRANTIES OR EXCLUSION OF DAMAGES IS INTENDED TO BE SEVERABLE AND INDEPENDEN
28. Import Export buttons in the Batch Processing screen When either button is pressed a dialog box will open asking the user either to name a batch file Export or to select an existing batch file Import Once a batch file has been exported the user can open the file with any text editor and edit the salient parameters of interest Each study must begin with and end with the study number Spiral studies contain an additional three parameters not included in circular studies See the table below for a list of valid parameters and their possible valid arguments with a description Valid InputFile valid file Interfile hdr ResultFile valid file Interfile img ROR mm Radius of Rotation in mm DetectorMode Number of gamma cameras O GDRO disabled 1 GDRC enabled 2 4 8 or 16 Number of OSEM subsets 68 TRIUMPH X SPECTO USERS MANUAL Numberofimages integer or All Number of spiral orbits Norits Startimage First spiral orbit to use in reconstruction Spiral step size in mm Endstudy Study Number Please note that the parameter names are case sensitive 1 e EndStudy 1s not the same as endstudy Troubleshooting This section covers the most commonly encountered warning and error messages generated by FLEX SPECT Please consult these for further information on each error warning message If the warning and or error cannot be resolved please contact customer support at Gamma Medica Ideas 8
29. It contains three items Protocol Name Although no fixed pattern protocol name is recommended to be precise and distinct It is recommended that the unique feature of the scan be specified in the name E g whole body close range spiral multipinhole etc Collimator collimator name can only be chosen from the drop down list Please make sure that the name be introduced in the standard training session at machine delivery The following are names for standard delivery collimators N1F90A10 single pinhole collimator 1mm aperture N5F75A10 multipinhole collimator mouse style 1mm aperture N5F65A10 multipinhole collimator rat style 1mm aperture standard parallel hole collimator TRIUMPH X SPECTO USERS MANUAL Scan Mode scan mode refers to the gantry movement for the scan There are four types of scan mode enabled by the current release of Triumph SPECT and they can only be chosen from the drop down list no gantry movement single planar image will be acquired Dynamic no gantry movement multiple planar images will be acquired with a series of pre defined time frames Tomo gantry will rotate 90 180 or 360 degrees based on setting while a series of projections images will be acquired at pre defined angle Based on detail tomo setting animal bed will either stay circular or inward at steady speed along axial direction spiral Dynamic with pre defined time frame a series of circular tomographic Tomo images will be
30. M I currently recommends for a general purpose reconstruction 5 iterations of 4 subsets as shown in Figure 2 4 2 FLEX SPECT can be closed by clicking the Exit button in the lower right hand corner of the screen or by clicking on the red X in the upper right hand corner A warning will appear to ensure that the user does not accidentally exit the program GDRC SuperSPECT FLEX SPECT is capable of modeling the physics of the pinhole and the pixilated detector and can thus dramatically improve the spatial resolution and noise characteristics of the reconstructed images Figure 2 4 3 shows a cross section of a pinhole collimator with the four key parameters that define 49 TRIUMPH X SPECTO USERS MANUAL the pinhole geometry FLEX SPECT automatically accounts for these parameters based on the name of the collimator For more information please reference Chapter 1 of this manual detected in the Interfile being reconstructed GDRC Geometry Detector Response Correction Acceptance Angle lt a gy Pinhole Aperture Figure 2 4 3 Cross section of a pinhole collimator FLEX SPECT uses a Geometric Detector Correction Response GDRC in modeling the collimator and detector This means a geometric approximation to the pinhole point spread function PSF is convolved with a Gaussian representation of the detector intrinsic spatial resolution as defined by the pixel pitch of the detector in order to appro
31. Medica Ideas 877 426 2633 Batch Files An alternate method to fill out a batch job is to create a batch file in a text editor such as Microsoft Notepad that contains the necessary information for each study Batch filenames need to end with the extension batch and the files must include the first two lines highlighted in Figure 2 6 4 to be recognized as legitimate batch files 67 TRIUMPH X SPECT USERS MANUAL ExampleBatchFile Notepad File Edit Format View Help elinfo F lex Recon Batch version 1 0 5 e study 1 Tnputhd le 0 5 5PECT_Datass16741111149 HDR Resulte7 le 0 4SPECT_Data Fusion_study img ROR mm 50 Detectormode 2 GeomResp 0 Niterations 5 Nsubsets 4 spiral 0 endstudy 1 Studyi 2 InputFile D ASPECT_Datass310813031 HDR Resulthi le 0 5PECT_Data MDP_Ratl img ROR mm 20 Detectormode 1 GeomResp 0 Miterations 5 Nsubsets t 4 spiral 0 endstudy 2 4 Study 3 InputFi le 0 5 5PECT_Datass 53612296 HDR Resulthi le s0 SPECT_Data spiral_MoP_scan img ROR mm 40 Detectormode 2 spiral 1 Numberotimages 411 5tartimage 1 stepsize 1 endstudy 3 Ln 1 Col 1 Figure 2 6 4 Example batch file illustrating three studies The easiest way to generate a template batch file 1s to enter a number of studies of the desired type into the batch screen and then export a batch file Batch files can be imported and exported by using the
32. Projections under the Tomo Settings will automatically update reflecting the number of list mode projection files found Next enter the Radius of Rotation in millimeters in the ROR mm field and select the gantry rotation angle from the Rotation drop down menu either 180 or 360 ColorSPECT currently does not support spiral orbits Finally select a name for the generated tomo Interfile by clicking on the browse button in the Save File field which opens a dialog box in which the user can navigate to the desired directory and select a file or type a new name A spectra file of the tomo list mode data can be generated by marking the Generate Spectra checkbox for more information please reference the Generate Spectra section of this chapter Once all of the fields have been filled out presses the Process button to begin processing The status bar at the top of the screen displays any pertinent information about the process and will alert the user when processing 1s complete If the Do reconstruction checkbox 1s marked and the Save File field below the checkbox has been filled out the tomo Interfile and necessary information are passed to the Batch Processing screen After the ColorSPECT processing 1s complete the user can start reconstruction by selecting Batch processing from the Select mode drop down menu Alternately multiple ColorSPECT jobs either the same tomogra
33. T OF ANY OTHER PROVISION AND TO BE ENFORCED AS SUCH FURTHER IT IS EXPRESSLY UNDERSTOOD AND AGREED THAT IN THE EVENT ANY REMEDY HEREUNDER IS DETERMINED TO HAVE FAILED ITS ESSENTIAL PURPOSE ALL OTHER LIMITATIONS OF LIABILITY AND EXCLUSION OF DAMAGES SET FORTH HEREIN SHALL REMAIN IN FULL FORCE AND EFFECT ALL SUCH PROVISIONS SHALL SURVIVE THE TERMINATION OF ANY RELATIONSHIP BETWEEN SELLER AND PURCHASER The printed terms and conditions of any purchase order or other correspondence of Purchaser or any vendor reseller in connection with which Purchaser acquires the Product shall not apply insofar as they seek to modify the liability limitations and disclaimers set forth in this document To enable Seller to properly administer its warranty obligations Purchaser shall a 76 TRIUMPH X SPECTO USERS MANUAL notify Seller promptly in writing of any claims b provide Seller with the opportunity to inspect and test each item claimed to be defective This inspection may be on Purchaser s premises or Seller may request return of the product at Purchaser s expense Such expense will be subsequently reimbursed to Purchaser if the product is found to be defective Adjustment is contingent upon Seller s examination disclosing that apparent defects have not been caused by misuse abuse improper application repair alteration accident or negligence in use storage transportation or handling and that the original identification markings have not been
34. Y GAMMA MEDICA IDEAS a INNOVATION FOR LIFE GAMMA MEDICA IDEAS Users Manual Triumph X SPECT Software Manual for Acquisition and Processing of SPECT images using Triumph X SPECT USERS MANUAL Triumph X SPECT Gamma Medica Ideas 19355 Business Center Drive Suite 8 Phone 818 709 2468 Fax 818 709 2464 This manual is the property of Gamma Medica Ideas Ideas and may not be copied or reproduced in any manner or form without the prior written consent of Gamma Medica Ideas Instructions in this manual are to be considered as recommendations only This manual and the data therein are subject to change at any time without notification Table of Contents NEO QUE O Miri AA Aida 1 SPECT SOT Wal SAA AAA 1 Features Of Thump OSPEC TTM ci 4 Set UD WINGOW sistance eran aa 4 SUUGY NA 4 PROLOG Ol n li 6 SCANIA Ns a e aaa 9 S CAMINO td E E N N ENE E AE E O O balens 10 Animal SUALUS A A aA e aa ae A a anaana a i 10 Camera statls mia eerie r A A A E A rer eee 11 DetallCameta Statlsinb A a e aa o e AA E EE 12 DICE VICEWEr WINO OW da 13 Calibration AVIV UIT CLO WW pecs eet er etek A AA 14 Gantry CaP abl On torio dci 14 UCT Uniformity Correction Fable lunar 14 QC OQuality CNECK oraren nese iae ia 16 POCO ON BCU CS veresen iea Ea em ars ator ature ar ancl usenet 17 Data Acquisition with Triumph SPECT assesses 19 TO tar me Connec ON ea eer r Tm TR rte nN Tren RTT aT er race N 19 TO State UNG Progr ai usa eek 20
35. able LUT EPT_ bin D LumaGEM Calibrations EPT_ bin Energy Peak Table EPT U_COLL D LumaGEM Calibrations U_COLL iain i table 66 TRIUMPH X SPECTO USERS MANUAL Most of these files should not be modified after installation of the gantry by GM I personnel but one file might need to be modified if the user needs to specify new isotope and or energy windows this file is the isotLUMdir file and is located in the D LumaGEM Acquisition directory The isotLUM dir file may be opened and edited with any text editor and contains entries partitioned into blocks of rows that belong to specific isotope energy window combinations see Figure 2 6 3 Each new isotope energy window block begins with a name designation contained in brackets e g TC 99m 20 as highlighted in Figure 2 6 3 Following this bracketed name can be any number of energy windows defined by three parameters winLowl winHighl and winPeakl all specified in units of keV e g a second energy window can be added to the same isotope energy window name by adding the fields winLow2 winHigh2 and winPeak2 The parameters Gain and CalRef should remain the same as for isotopes of similar peak energy isotLUM Notepad AE File Edit Format view Help To Gom 10 wridLow 13 3 wndHi ghl 14 7 wndPeakl 140 Gain Figure 2 6 3 The isotLUM dir file For help modifying this file please contact customer support at Gamma
36. antry calibration should solve the problem Data Management Error Triumph The protocol Test ts linked to a Scan Protocol cannot be deleted Just like the clinical system studies protocols and patients are tightly controlled Once set up in the database and a scan has been performed it will not be removable Final Exit Triumph T Close other open windows before closing the Triumph y SPECT Application This is the final check up point for exiting Triumph SPECT Before hitting the Exit button O all windows have to be closed 45 TRIUMPH X SPECT USERS MANUAL Note These are only partial of the messages implemented in the program Other message boxes will show up when induced with errors or checkpoints Follow the instructions the boxes and you should be able to carry out a scan smoothly 46 TRIUMPH X SPECT USERS MANUAL Chapter FLEX SPECT Software and SPECT Reconstruction data acquired with pinhole collimators double click on the FLEX YMI SPECT icon located on the desktop The start up screen shown in Figure 2 4 1 will appear T o launch the FLEX SPECT program for reconstruction of SPECT x FLEX SPECT Reconstruction Gamma mevica tpeas gt case Choose if vou preter the Sinale Reconstruction Batch Processmy or Color SPECT a modet MaiS Peores ng Cole SPECT Reconnect Exe Figure 2 4 1 The start up screen for FLEX SPECT Under
37. ar SPECT and x ray CT Figure 2 1 1 Photograph of FLEX Triumph imaging subsystems use different system laa to approximately acquisition and processing software loaded on the SPECT and CT PC s respectively Co registration of the CT and SPECT images are performed with separate software on the CT PC and fused images are displayed using VIVID NOTE It is strongly advised NOT to install other software onto either the SPECT or CT computers as it may interfere with the proper functioning of the equipment SPECT Software Triumph SPECT imaging package consists of two software entities Triumph SPECT for data acquisition SPECT system maintanance quality control and FLEX SPECT for image processing and reconstruction Both are proprietary product of Gamma Medica ideas and are loaded with two short cut icons on the SPECT PC TRIUMPH X SPECTO USERS MANUAL User Interface The user interfaces for Triumph SPECT and FLEX SPECT are both essentially multi tabed multi tiered menu The first tier contains icons or drop down menu bar for choosing individual applications the second tier contains push buttons and or input fields for the specific operations which can be performed within that application If the operations need to be performed serially push buttons and or pop windows are activated serially Multiple push buttons are activated if operations can be performed in parallel individually The sof
38. bed 2 Move up and down the patient bed 3 Move left and right the patient bed a 4 Move in and out the gamma ve E E Details Cameras Figure 2 3 16 Instant images after object positioning 5 Rotate the gantry In addtion user can choose to view different head view energy window choose different energy window or click Details to see all camera heads Please reference the chapter 2 of this section of manual for detail introduction of all the features in this viewer window operation In this paragraph only basic function is cover to enable user to start the scan Start the Sacn Automatic and affine positioning After all the information in put into the left panel and the animal secured on the bed at the front deck you can click the start button to start scan preperation Upon pushing start first step for automatic targeting will be presented Triumph Please use the hand controller to position the center of FOW to laser point and click Next If the subject ts already within the FOW of camera click Skip Figure 2 3 17 step 1 of scan position the target of interest 29 TRIUMPH X SPECTO USERS MANUAL If you have already positioned the animal into the gantry and you are satisfied with 1ts position click on skip Otherwise use the handcontroller and move the animal bed towards the front gantry entrance where the guiding lasers are positioned to activate the laser
39. ces for UCT calibration SynapSPECT requires an image without the collimators therefore a 10uCi point source e g a 104 liquid at the bottom of an Eppendorf tube or in a syringe would be enough Position the eppendorf tube on a regular mouse bed and send into the gantry and have the cameras midway or adjust so that the average count rate could around 5000 8000 cps To acquire extrinsic images a liquid flood phantom is needed GM I provides a 2 x2 flood phantom for single pinhole collimators and a 5 x5 phantom for all parallel hole collimators Total activities in the phantom must be adjusted based on the count rate to achieve the most efficient and effective calibration Usually 10mCi of Tc99m for single pinhole 2 x2 and 5mCi for parallel 5 x5 is recommended Due to the shape of the flood phantom extrinsic UCT can only be done one pair of camers at a time To position the phantom use the supplied phantom holder instead of animal bed please refer to the oprater s manual and have the cameras as close to the phantom as possible centered well 39 TRIUMPH X SPECT USERS MANUAL Figure 2 3 33 Flood image acquisition for UCT The cameras are in service position closing in on the flood phantom Procedure for UCT calibration To run UCT click into the calibration window and select UCT tab In the window from left to right fill in all information asked With the following guidelines So
40. ct of the study can be changed and additional patient can be added to the list Upon finish click the Update button and all the modification will be made to the study upon users confirm 23 TRIUMPH X SPECTO USERS MANUAL NOTE Patient can not be deleted unless the entire study is deleted from the list So please be carefule not to make unecessary mistypes NOTE Add and Update should serve as a good indication whether you are adding or changing studies Build a Protocol To build an imaging protocol click on the Protocol tab in the set up window to bring the protocol page into the front Triumph SPECT Set Up udp Prolocol Eb Prolocol Lev Praca H San Moda Dase plion Protocol Name lemina imka hamn ME E E E J E Hora D Cedie Me1paabosp ft of Aine Wide hi ROR mn FOY mam Abat E ie bora We F Edil Deltebre Add Figure 2 3 9 Original Protocol window To create a protocol work from Protocol Name input field and down wards to fill in all information regarding the system setting note that the detail setting window at the bottom will change according the Scan Mode selected So please select the Scan mode before trying to fill in any details NOTE Radius or Rotation ROR can always be modified later using the protocol builder see later section So a guessed one or a ball park usually is good enough t
41. ction Error Triumph Socket connection ts failed Please check all the hardware connections and restart the application This message will show up if the gantry is not connected to the computer or if the DDROB is not communicating with the program Check if the hand controller is switched and if the telnet process has been completed Warning upon an exiting action Triumph This will close Set Up window Do you want to continue 42 TRIUMPH X SPECTO USERS MANUAL Triumph This will close Scan Data Viewer window Do you want to Continue These messages will show up every time user click a close button or hit the cross symbol of a window This is to prevent accidental keyboard stricks Warning for missing information Triumph Rotation Angle Number of projections and Time per Projeciton seconds are mandatory Triumph Source isotope will be automatically calibrated Pleaze choose a different isotope for target These type of messages will inform user what is missing or incorrectly put during a set up process these messages is imbedded in all set up windows scan windows and calibration windows Warning for modification Triumph Existing Protocol will be modified 7 Whenever a protocol or a study has been modified and user struck the Update button the message will appear for user to confirm purposeful action 43 TRIUMPH X SPECTO USERS MANUAL Confirmation on exit
42. d the resetting Requested counts This input field defines the desired counts per projection 17 TRIUMPH X SPECTO USERS MANUAL program will use this input to calculate the acquisition time needed per projection 18 TRIUMPH X SPECTO USERS MANUAL Chapter Data Acquisition with Triumph SPECT o switch the mouse and keyboard control from the CT monitor to the SPECT monitor hit the Scroll Lock key on the keyboard twice and then hit enter make sure that the mouse was not moving while switching To Start the Connection Before starting the acquisition software a communication needs to be activated between the SPECT PC and the camera read out board DDROB To do this open the DOS command window on the SPECT PC by right clicking on the Start botton at the bottom left corner of the screen and choose All Programs gt run SE My Computer Control Panel Set Program Access and Defaults ES Printers and Faxes Paint y Help and Support y Search Opens a program Folder document or de Log Off Turn OFF Computer All Programs gt 6 untitled Paint Figure 2 3 1 Invoking the command window When promped type in cmd and hit OK the command window will open 19 TRIUMPH X SPECTO USERS MANUAL Type the name of a program Folder document or Internet resource and Windows will open it For you Open cmd Figure 2 3 2 Invoking the c
43. er window To export data as standard interfile select the targeted scans from the right window then go to the top menu bar and select Study gt Export gt Interfile Triumph SPECT Scan Data Viewer GAMMA MEDICAIDEAS INNOVA TON BeentDemo Protocol Name Scan ID Scan Mode Scan Time Scan Description TESTRUN 0 11 2000 5 04 56 a f 5 Dc Aa ome 8 7 2008 4 12 05 AM p y echble i a 8 13 2008 3 29 45 Yogesh TESTRUN TheS4bba deth 4bt Dynamic Tomo B 5 27008 amp 12 42 PM TESTRUNZ2 Deld273 cdeo469 Dynamic Tomo 0 12 2000 3 00 01 TESTRUN2 23c0cbel 1146c Dynamic Tomo 0 13 2000 3 23 22 TESTRUN Aas tht 774 448 Dynamat Tono 1 12 2008 8 07 19 TESTRUN 3B4e37bb a3bO 43 Dynamst Tomo B 12 2008 74510 TESTAUN2 32414417 246b 4b Dynamic Tomo 8 11 2008 5 17 28 TESTRUNZ Jat ddeS 3cd5 4e Dynamic Tomo 8 11 2000 12500 TESTRAUN2 Je93c50S bI1t 4d4 Dynamic Tomo 0 12 2000 4 56 31 Figure 2 3 29 Export data Upon selection a message box will show up asking user to verify the destination of the exported file By default the data are stored in C Interfile directory If user would like to choose a different data path click on the path box on the right and define a directory Location C Alntertile Figure 2 3 30 Select destination of data export After data path selection click Export the selected data will be automatically converted to the two file 1mg and hdr interfile format and stored
44. et up window will be invoked for you to generate new items for your libraries Upon close of the set up new items will added to the related list which you will be able to see when pulling the drop down list again Select the 1tem you want and continue with your inputs Patient position and Organ are not mandatory field but it is encouraged to be filled for the completeness of the database Actvity Administration only needs to be modified when an injection pump 1s attached to the system and users intend to activate during image acquisition By default one injection activity will always be filled in but 1t will not affect any imaging acquisition 1f there is no pump connected aD TRIUMPH X SPECTO USERS MANUAL Operator and Descrition are also optional fields but it is recommended that they be filled for the completeness of the project By default List Mode Data are not checked hence not saved for 1t consumes relatively large memories Under the circumstance when users wants to reprocess the data under a different energy window new 1sotope partial time span or for camera unifomity pixel correction list mode data can be saved by checking the toggle Position the animal by hand At any time during the Triumph SPECT operation animal or imaging objects can be positioned into the gantry by using the hand controller to move the patient bed out to the front deck Please reference Triumph manula sect
45. ich camera head to monitor view and using which isotope and energy window as filter e The clock The middle panel reflects the gantry angle of selected camera head corresponding to the projections on the left e The image information The right panel is a data information summary Calibration Window Gantry Calibration Triumph SPECT Calibrations GAMMA MEDICAADEAS gt Gantry Cabbratron UCT QC Bed Porton 32 653 Gantry Angle 11 272 Gary Calibuation Status Stat Chose Figure 2 2 11 Gantry Calibration window Gantry calibration is the simplest interface of the program It has two panels the top panel reflects the current bed position and gantry angel for user s reference The lower panel is a information box that reports the start and finish of the process The start button starts the calibration UCT Uniformity Correction Table UCT window is for users to acquire isotope energy collimator specific flood image for camera uniformity calibration It differed from scan window in that 14 TRIUMPH X SPECTO USERS MANUAL 1 Itis only for acquiring static image 2 A calculation process will be automatically following the flood image acquisition to generate UCTs for more than isotopes therefore there are additional settings that 1s usually not needed in regular static scan 3 UCT calibration will have an option to be followed by a QC procedure so there is an additional setting to check it
46. ick Process Selca mode Color SPECT Color SPECT Pile Intormadion Choose Color SPECT File SPECT Testing DaltaiaticihLMDatalspRes PH1O Tchsm 20 1931 bin aa Study Hame Spatial Hesolution direccion Patient Name System Tests Patient ID 0001 laninpe TCS 205 Collimatoe PA Prabocal Saale Output Save Dolor SPECT Interile i Generate UET M Save File DiLolorsPECIT Testing DalaStoticiSpHes_ lt mg Generate SPECTRA M Do reconstruction I Figure 2 4 10 The ColorSPECT static protocol Static list mode files have the same name as the Study ID that was supplied by the user when the data was acquired Once the list mode data have been selected a new Study Name Patient Name and Patient ID must be entered in order to populate the new static Interfile that is to be generated It is a good practice to give a descriptive name for the Study Name and to use the same Patient Name and Patient ID that was used in acquiring the data Next from the Collimator drop down menu select the collimator that was used to acquire the data It is important to choose the correct collimator as an incorrect choice will severely distort the resulting data From the Isotope drop down menu choose the desired isotope and energy window There is no inherent constraint in the choice of isotope and energy window To obtain the best possible images each projection should be uniformity corrected In order to perform the uniformit
47. icular mode Therefore the content changes based on the which scan mode has been chosen TRIUMPH X SPECTO USERS MANUAL Static Settings Static Scan if static scan 1s chose user simply need to Acauistion Counts Kilo put in the stop condition either by time or by total final counts Acquisition Time sec Figure 2 2 3 the Static detail setting windowa Dynamic Scan for a dynamic planar scan user need to define the time points and time frames in the following detail window e Num Of Frames how many planar images you wish to acquire Num Of Frame Interframe Pause Frames Duration Duration e Frame duration how qe 0 long do you wish to acquire for each image e Interframe duration do Phase3 you wish to wait during frames and how long e Phases if you wish to Figure 2 2 4 Dynamic scan detail setting set different frame duration e g some frames are 10 sec and some are 20 sec these frames need to be separated into different phases e Pause if checked the program will wait user s keyboard command to start the second phase Dynamic Settings Phase2 O Tomo Scan there are two kinds to tomo scans the circular scan 1s the standard tomo scan and the setting window looks like this Tomo Settings O Helical Circular Rotation Angle 360 v Num Of Proj 64 v Time per Proj sec C Compensate Decay Figure 2 2 5 Tomo Scan detail setting window e Rotation Angle defines the distance for gantry ro
48. in pre defined data folder Triumph Successfully exported list s Db3ce72e c208 4f9c 86ff cf02e66423c8 16598040 ac5c daba a3de 0633b437fa391 1cc6b1 c2 8740 46cf b943 406e9ab1 3ict Figure 2 3 31 Notice for successful data export NOTE The exported data file names are results of Triumph SPECT internal database tracking logic After export user can change the file name to their liking as long as the correspoding data path in the hdr file is changed accordingly also In similar way standard interfiles can also be imported into the database 37 TRIUMPH X SPECTO USERS MANUAL Service and Maintenance Calibration j 2 5 Change a Collimator a Collimator exchange in Triumph gantry requires gantry rotates to specific angle so that the targeted camera head is positioned at proper height at the service door To automatically perform this rotation Triumph SPECT implemented a collimator exchange routine Click into the calibration icon shown above window and on the top menu bar select Tool gt Change Collimator and follow the instructions Gantry Calibration To ensure accurate gantry rotation and limit switch sensoring Gantry calibration needs to be performed on a monthly basis or anytime when the gantry was powered down To perform gantry calibration click into the calbration window the default window should be gantry calibration tab Click on start the gantry will a
49. indow study list and the right panel will be ready for you to generate another study a 22 TRIUMPH X SPECTO USERS MANUAL Etude Protocol Crating Fludy Liar Study Hane GENOA Araolidian itat SUPEHPHAM TOH t gt Vis Erhi Damia Triumph SPECT Set Up Shady Hana lnventigain Mijom at Shady Penacrigeticnn Shady Hitos Patent Name Frasca Mame Sean ID 4 Hapoel Scan Figure 2 3 7 A study Added to the lists GAMMA MEDICA IDEAS A Lae Patian lafoomation Pate Hane a an Hain ok om UU Bee feat tt hal Drop Auk Pantera Sean Mode Sean me Sean Desenplion bemos Scan View Scan Lu Cn To modify a study select the study name in the list and click on the View Eidt button at the left bottom an editing window will be presented o Triumph SPECT Set Up GAMMA MEDICAJDEAS gt INNOVATION FOR LIFE Study Protocol Exnling Study List Pater Irburmation Study Nama Descaption Shady Name Herububon tert Patieet Nano Y Ses Male v GEOCAL Herubvton teal Hesolubon measure SUPERPHAN TOM investipetos Opecator JeAnn Woighh qm DOD 3 24 2008 Study Desenpbon Description Rescluiion mescunnant M close tradas ol all collmatocs Add Potions Study Mirtory Potent Name Protocol Name cen 10 Scan Mode Scan lane Scan Description Supee Phactom lt gt Hepes Scan Remove Scan Vew Scen gt Cunas Figure 2 3 8 To edit an existing study In this window all aspe
50. ing action Triumph Please click OK to abort scan or click Cancel to continue can When an on going process is interrupted by hitting a stop button these type of messages will show up asking for confirmation Processing Error Triumph The ROR value set does not match with define ROR value in the protocol Please press OF to reposition camera Press Cancel to change the protocol with current ROR value or create a new protocol with this ROR value This type of check point message will show up 1s the gantry sensors for bed position camera position or gantry position does match a setting The ROR mistake is the most common case for the program request a very precise value When shown with this message double check the setting value and hit set again till it stops showing Gantry performance Error Collimator Change Following error occured while reseting the camera position Gantry is not calibrated Press OK to reset the camera positions again Press Cancel to abort the Collimator change process 44 TRIUMPH X SPECTO USERS MANUAL Gantry 5ystem Error A The gantry is not calibrated or the calibration is outdated Please calibrate the gantry before any data acquisition When a gantry calibration is out of date which will happen after 1 month or anytime with the machine powered down any action that requires a gantry position sensor will produce such messages Click OK and proceed with a g
51. ion 1 operation manual to perform this operation Remember that for animal bed to move all the way to the front no imaging module 1 e cameras x ray tube and detectors can be anywhere in the gantry off limit switch When in doubt push all the out buttons on the hand controller to make sure The following picture shows the animal positioned secured and connected to the gantry gas anesthesia system Need an animal picture Figure 2 3 15 Animal positioned and ready to be imaged Alternatively the bed can also be sent out by the protocol builder bed setting fuction Please reference later section on how to do it 298 TRIUMPH X SPECTO USERS MANUAL NOTE At this point the scan can start The following instructions on how to fine tuning the animal position in gantry are optional Automatic centering of the target of interest is provided by the scanning procedure When the animal or object is sent into the gantry you will gain you first glance at the object you want to image on the right panel of the secan window At this point you can either click the start button on the scan G 3 s j window or use the hand controller 93 GAMMA MEDICA a to fine position your animals and or have a thorough check of your AE position Please reference the iii section l of this manual for detail hand controller movement to 1 Move in and out the patient
52. itor In the A LumaGEM_Path parameter enter the estu ias one installation computer s set up typically he300 this will be D LumaGEM as shown in Figure 2 6 2 timewinLow 0 inia eg Figure 2 6 2 The LMPro ini file e Double click on the FLEX SPECT icon on the desktop The FLEX SPECT start up screen should appear as in Figure 2 4 1 If the start screen appears the program is working properly If an error message is displayed please reference the troubleshooting section of this chapter Parameter Files Spect ini amp LMPro ini FLEX SPECT accesses two parameter initialization ini files that set up paths reconstruction options and default values Both files reside in the installation directory typically this is C Program Files FLEX SPECT and have the filenames spect ini and LMPro ini Please note that the parameter names in these files are case sensitive 1 e GeocalPath in spect ini is not the same as geocalpath Spect ini The spect ini parameter file is the main parameter file and controls the reconstruction options and default values Short descriptions of the parameters and their possible values are given in the table below Valid Default Parameter haces Vawe MS pixmag Interpolation in reconstruction in reconstruction GeomEffc_single float Pinhole sensitivity cosine power term for single pinhole collimators 64 TRIUMPH
53. l window bottome panel 34 TRIUMPH X SPECTO USERS MANUAL Dynamic Tomo Settings Rotation Angle v Num of Proj v 8 16 32 Time per Proj sec 54 Num of Scans gt 1 Figure 2 3 26 Dynamic tomo setting Comparing with the standard tomo window the choice of Helical vs Circular is removed as the dyanmic scan can not be performed with helical mode In addition one more input field is needed how many frames to be performed After setting up the protocol all scan operation of Dynamic scan is the same as the standard tomo scan NOTE There is no phases Dynamic tomo scan can only be performed with fixed rate time per projection Cardiac or Respiratory Gated Scan At this release Cardiac or respiratory gated scan has not been enabled After a Scan At this release Acquisition using Triumph SPECT reconstruction using FLEX SPECT and image display and analysis using VIVID are independent and unlinked Therefore the acquisition all projection images can only be qaulitatively viewed the Triumph SPECT data viewer window For reconstruction or furhter processing and analysis projection data need to be exported to a common folder on the PC which is accessible by other software Data Viewing To view acquired data click on the Data Viewer icon on the top menu bar the image database will be presented to you 35 TRIUMPH X SPECTO USERS MANUAL oan Data Wher T
54. l window will appear see figure e Scan Status a message box that updates scanning progress and report errors E g for dynamic scan it reports when every frame is starting for tomographic scan it reports when projection is acquired e Gantry Status an interactive indicator meter of the bed position gantry angle and the ROR a fel ee TRIUMPH X SPECTO USERS MANUAL Detail Camera Status By clicking the Detail button in the camera status panel in the scan window a detail camera status window will be invoked Emeryr Spectre Camere 1 UCT Tc F9m_NSFISAIG Energy Todhs Persistent j Spectra ET 202 windows seeps Collimators ROR mm 40 000 40 003 Use cunent ROR panel FOV mm Persistence Tene 52 100 57 104 UCTTC 99m_N5F75A10 Set ROR Bed Position 73 048 Set Bed Pasition Gentry Angle E Set Gantry Angle Sat Parameters Figure 2 2 8 Detail Camera Status e Camera Persistent Window Display real time signal of all camera heads the cameras heads are indicated on the top with each screen and color coded In the middle a scale was place to adjust the accumulation period before display E g a 14 secs scale means that all images displayed are accumulated signals for 14 seconds e Energy Spectra Accumulated all time energy spectrum for all cameras The colors of the lines matches the color codes of the camera head
55. lect the protocol and click View Edit button NOTE Unlike the Patients isotopes from a protcol can be removed by clicking the Remove button or even the entire list can be cleared So be careful during setting to avoid accidental deletion Build a Protocol Using Protocol Builder Itotopa Setting ros gt To invoke the protocol builder click into the scan window p eerw amd the right of the Protocol input filed click on Builder Gantry Seating e a Study ME en 56 079 Patient A J rov lel LEEG Protocol v C gt G t ROR Ded Position Figure 2 3 11 To invoke a Protocol Builder 29 048 sesedro Fill in all the information on the information panel For Gantry Angle 354 394 Set Gantry Angle 25 Required Cointe Per Proj Create Protocol TRIUMPH X SPECTO USERS MANUAL ROR bed position and gantry angle use the hand controller to move the cameras and pick the position as you like Note Gantry angle should be kept as default to assure optimal rotation unless for static scan After all parameters have been determined Enter the requested counts for program to calculate acquisition time Note Requested counts should be serve as reference In the actual protocol user should double check the acquisition time When all things are set click Create protocol the window will return to protocol set up for user to Add protocols To Perform a Scan
56. ment ET or cas dd 45 A ab Taste a od ee E etd nel eerie ine nee Seatac lea mene Daman eset nator 45 FLEX SPECT Software and SPECT Reconstruction 47 SINgle Reconstrucci n 47 GDRCeSUpCISPEG T wa tacasrsetiuasentsrtioaiepsdua nice sananmetnd ona A 49 Spiral SPECT RECONSTRUCTION cara la as 51 BUC PU CSS Sy a 52 COLO PS PE G rere ee RC ROR RC One RT me ee A nr aren ae 54 Static ProtOCO wie ca eare o a ae 55 TOMO POLO CO A wager eae aAa E 57 Generate UC Tiene inrni ars taeda sacra aes ponerse oia 60 Generate Spectator a Se Bassa rete te whos Never ete bes 60 Cardiac Gated SP ECP srcmscswenadvesnecurenusagsnsanetveddvcmenessannenases 62 APPEN anat dk 63 Stallati GUld Esera 63 Parameter Files spect ini LMPTO INl oococcccccnnnconnnonnncnnncannnos 64 SPECEINI aaan E oateta nate ante wand be teeeneteon Domeeaes fastens 64 EMPLOI beens 65 Parameter Files I COlOrSPEGT ANOS da 66 A O nan enn ee ne 67 NM ae18 ola are le a lake idas 69 TRIUMPH X SPECTO USERS MANUAL Chapter Introduction his manual describes the use of Triumph SPECT the software used for acquiring images in the Triumph instrument and the use of the FLEX SPECT which reconstructs the acquired images This manual is intended for use in direct conjunction with Section 1 of this manual and is not intended for use on its own It 1s recommended that the reader become familiar with Section 1 prior to reading this software manual Nucle
57. n list the center 10 TRIUMPH X SPECTO USERS MANUAL screen will display the bio graph in real time To view all active vital signs at one glance click the Detail button under the graph and a complete animal vital status window will be presented Note that oxygen level 1s also incorporated in the graph for user elected upgrade Also both cardiac and respiratory statuses are presented in two formats the conventional histogram and a rhythmetic chart The clear button will clear previous cumulation and start the charts from a fresh beginning Triumph SPECT Animal Status GAMMA MEDICA IDEAS Temgertuin Anagaraboty Firth Cardhac Ahytha Temperature c Respe story Er tren ret Carctec Fiyin me Clear Clam Clear Oxygen Level Nespearory Mhythen Histogram Cardiac Myth Histogram Close Figure 2 2 7 Complete animal vital sign status Camera Status e Monitor window setting choices By selecting different input Persistence Image _ y and different head user can choose to monitor the camera by persistent image or count rate chart or any head in the system User can also adjust energy window to see variously filtered image which should help determining whether or not protocol needs to be modified e Monitor Display of persistent projection images or histogram based on the input setting defined above To monitor all input of all cameras click on the Detail button a camera detai
58. ns four sections study list study info patient addition and study history Esvidina Study Leil Pate Inbirmisadron Siudy Hama Dnserpii n 1 Patient Hana GEUCAL SUPEHPHAM I CIH Weight gm Lit Us a a 1 em 3 Study Higher Pirtocol Hama Scan I View sede Fiqure 2 1 1 Protocol window TRIUMPH X SPECTO USERS MANUAL l Study List This explore style window contains all established studies displayed by names For a brand new user this panel should be empty Established study can be viewed edited and deleted with action buttons listed at the bottom of the panel Study info This section contains critical identifiers of a study Study name Generally speaking studies are the purpose or theme of a research project or an experiment E g whole body distribution mAb reanl clearance folate 001 Investigator Operator Although not a mandatory field it 1s encouraged to be filled to facilitate organization of studies especially for core facility instruments Study Description Free style text box for study notes not manadatory Patient info Each study can be linked to multiple patients and this section 1s for users to fill up the patient list for the particular study Patient Name under usually condition this section is the spieces and strain name of the animal to be imaged A patient for Triumph could be a mouse rat hamster or even a rabbit It is recommended that the strain and o
59. nu will 60 TRIUMPH X SPECTO USERS MANUAL become active and two options are available Summed and Individual spectra The summed option generates a spectrum per gamma camera in which the resulting spectra are the sum of all the individual pixel spectra The individual spectra option generates a file containing the spectra for each pixel in the gamma camera s separately and stored in a 2 D array of pixel versus energy bin The spectra files generated are text files with extension spe that can be read with any text editor or spreadsheet The energy bins are keV in size and the low high value of the energy axis can be controlled in the LMPro ini file using the two parameters EnergyWinLow and EnergyWinHigh please reference the section on parameter files in the appendix of this chapter e TRIUMPH X SPECTO USERS MANUAL Chapter Cardiac Gated SPECT Cardiac Gated acquisition and processing will be made available once the reconstruction 1n FLEX SPECT is completed TRIUMPH X SPECT USERS MANUAL Appendix his chapter covers further information on the FLEX SPECT software installation parameter files batch files troubleshooting customer service and finally a general warranty Installation Guide FLEX SPECT is a stand alone package that can be installed on multiple computers to facilitate ease of use and speed of reconstructions The program has the following system requirements The program may run at a
60. ny errors and or warnings are generated please refer to the Troubleshooting section in the appendix Clicking on the Hide Report button in the right hand column will return to the list of batch jobs ColorSPECT Note ColorSPECT is no longer needed for multiple isotope processing for it has already been implemented in Triumph_SPECT during the acquisition in the post acquisition process invisible to user The ColorSPECTTM session is remained for UCT re generation and spectra processing In the near future both will also be implemented in the Triumph_SPECT and the colorSPECT function will be removed from the FLEX _SPECT package The ColorSPECT feature in FLEX SPECT allows the user to process list mode data List mode data is a data format in which every radiation event detected by the gamma camera s is recorded as raw data in most cases to be processed at a later time The raw data is usually in binary format and can be processed to recover the estimated position and energy deposited in the gamma camera of each event List mode data are to be compared with frame mode data which include standard tomography Figure 2 4 8 Image of a nude mouse with l i 123 159 0 keV in the thyroid and Tc 99m datasets Frame mode data are list mode 140 5 keV labeled MDP in the bones data that have already been processed e g events outside the desired energy window have been discarded and events inside the energy windo
61. o start Like Patient to Study protocol is not finished until isotope s are chosen So after the camera settings please put in all the isotopes and the energy window of choice into the isotope set up window and click Add In the example a protocol was established to acquire tomographic image of a high resolution phantom at a very 24 TRIUMPH X SPECTO USERS MANUAL close ROR with a multipinhole collimator using Technictum 20 window The simplest mode of tomo was selected meaning only circular mode but a full round of rotation Triumph SPECT Set Up Study Protocol E sling Peofocol Leet liotope Settuungs Protocol N Sean Mode Description Protocol Name Clase Range High Sans NIFSOAIUG Tomo NSE SA10G Tomo v NSP MATO T Tomo Collenator WSF7SAIO gt Lnesgy Window 20 v Sean Mode Teme y lsmtnpo Window Name Derenphon clove sodras acquredron eth tc 39m 20x mdtipirbicds colima os Add Remove 6 te Mode Clee Mone Codec Hespuator lt gt E of Bins Window Sune ROR fem 15 000 15 000 FOV im 46 270 4R 270 Tomo Solbes Hebeal Crain Rotation Angie 3650 v Nam OF Poj GA v Butter Tene per Proj ftoc Compentate Decay t gt View Edit Delete Aas Return Figure 2 3 10 A protocol ready to Ada Similarly Add button will add the protocol to the left window s list and make the right window ready for another addition To modify the existing protocol se
62. ommand window In the command window type telnet 10 1 1 10 to start the communication with the DDROB ce CAWINDOWS As ystem32dcmd exe Microsoft Windows AP Version 5 1 2668 CC Copyright 1985 2661 Microsoft Corp C N Documents and Settings Admin telnet 1480 1 1 16 Figure 2 3 3 Telnet to DDROB User will be asked for username and password which are root and ideas respectively Password entry will not be shown on the screen After entering the password hit return key The cursor will move down and connection will established There will not be and message occuring on the DOS window indicating the established connection Please proceed to open the acquisition window To Start the Program am Triumph SPE The Triumph SPECT shortcut icon can be found on the desktop of the SPECT PC doulbe click on it and an inquiry window will open to ask for system configuration Camera s Settings Select the Cameras for Triumph SPECT Application e Camera Camera he Camera2 O Camerad Lo Figure 2 3 4 Triumph_SPECT initial window camera setting Usually for a single head system only Camera 1 can be checked 1 e Camera 2 4 toggle boxes are inactivated For a 2 head system Camera 1 and 2 will be active yet user can choose only to use one head Similary for a 4 head system all toggles are active and user can choose any configuration Check 30 TRIUMPH X SPECTO USERS MANUAL
63. onstant use of the system To run QC prepare source isotopes in a similar way as for the UCT then click directly into the QC tab in the calibration window Triumph SPECT Calibrations GAMMA MEDICAADEAS i gt Ganty Cakbraten UCT BE Souee lolepe Te Cima a Preso gp indre DPEH UCT NOME Coli atin HSFFSATO a Tefal Coura Fdol 3000 Ga artato Dilpid Fo Cirst s i 1 2 UL Fitri Desta MTM Shop i Figure 2 3 35 QC window After putting in necessary information and positioning the source and cameras click Start the program will perform a standard static acquisiton and calculate whole FOV uniformity quality factor standard deviation over mean pixel values Error Messages and Troubleshooting This section will highlight some of the many check point message boxes that should guide users away from mistakes and to proper next steps 41 TRIUMPH X SPECTO USERS MANUAL Gantry Connection Error Gantry System Error T Unable to communicate with gantry Please check the Followings 1 Is gantry powered on 2 ls the com port cable connected properly 3 Has x ray tube been disabled from the hand controller Retry Ignore Most commonly user would get this message when trying to start Triump SPECT without switching the gantry control to SPECT computer on the hand controller User can choose Ignore if only want to view or export data Program Conne
64. ool for processing a large number of reconstructions of all types circular spiral multi pinhole single pinhole etc Each reconstruction is filled out individually and the batch job is started at the user s convenience Batch processing is particularly convenient for starting long jobs intended to run overnight It is also an integral part of ColorSPECT processing see the ColorSPECT section of this chapter for more information The Batch Processing screen shown in Figure 2 4 8 can be opened by selecting the Batch Processing option in the Select mode drop down menu An alternate method is to create a batch file For more information please reference the Batch Files section in the appendix 452 TRIUMPH X SPECT USERS MANUAL PA FLEX SPECT Version 1 0 5 gle ef om ma q ye T p n 7 FLEX SPECT Reconstruction amma menica ipeas gt al Please add your studies and click Reconstruct Selca mode Batch Processing Study Study ID l HI ciregAOASO_ SATI Hi Corecg_ez 0 HI Comeg_re 5 HI CT SPIRO line Ph Edit Study Hemove Study Hemme all Studies Escil Figure 2 4 8 The Batch Processing screen By pressing the Add Study button the user can enter as many studies as desired using an interface screen that is nearly the same as that for the Single Reconstruction mode The key difference is that the Interfile to be reconstructed has been selected the user presses the OK
65. or 1010 Protocol Tomo Tama Settings Oatu Save Color SPECT Interile FF F Sumber of Projections Save File timization DalaPropcolon Lines ourccHA Umm mg POR mm Generate SPECTRA M Flotabion Do reconstrucilon E Orbit Sane File 11010 Optimization Dataline Source A Plmm img Exit Figure 2 4 12 the ColorSPECT tomo protocol 57 TRIUMPH X SPECTO USERS MANUAL Figure 2 4 12 shows a dialog box opened to the D LumaGEM LMData folde r and displaying the two types of list mode data The first two files listed are examples of static list mode data for which the Study ID has been used as Look in O LMData v My Recent Documents Desktop My Documents de e En Tomo_13 29 49 000 E Tomo_13_29 49 001 E Tomo_13_29 49 002 E Tomo_13_29_49_003 E Tomo_13_29 49 004 E Tomo_13_29 49_005 E Tomo_13_29 49_006 E Tomo_13_29 49 007 E Tomo_13_29 49 008 E Tomo_13_29 49 009 E Tomo_13_29 49 010 E QC TC 99m 20 1C10 1 E Tomo_13_29 49 011 E OC TC 99m 20 NONE 1 ES Tomo_13_29 49 012 E Tomo_13_29 49 013 E Tomo_13_29 49 014 E Tomo_13_29 49 015 E Tomo_13_29 49 016 E Tomo_13_29 49 017 E Tomo_13_29 49 018 E Tomo_13_29 49 019 E Tomo_13_29 49 020 E Tomo_13_29 49 021 E Tomo_13_29 49 022 E Tomo_13_29 49 023 E Tomo_13_29 49 024 E Tomo_13_29 49 025 E Tomo_13_29 49 026 E Tomo_13_29 49 027 E Tomo_13_29 49 028 E Tomo_13_29 49 029 E Tomo_13_29 4
66. ounts the minimum count every camera has to obtain in order to complete image acquisition Delay Time Waiting time between the start button is pushed to acquisition really starts This 1s very helpful when prepared flood phantom is too strong gt 30kcps QC toggle box Once checked a QC procedure will automatically follow the UCT calculation acquiring a static image with the updated UCT QC total counts similar to the UCT total counts this input field defines the minimum counts each and every camera has to obtain before calculating QC factors e Progress Window Information box that reports the status of the UCT acquisition and calculation e Camera Status The same camera status window as in the scan window QC Quality Check The QC window is an independent window although usually invoked after UCT is calculated User can click to the QC tab directly and acquire flood images and have the quality factor checked Triumph SPECT Calibrations GAMMA MEDICA DEAS gt Gentry Cabbratrom UCT ac Camera Slober Persistence image 1 w Enmgp Window OPEN v UCT INOME Total Counts Kilo 3000 Generale Output For Cameras gt v 1 vi 2 4 _ UC Progress Details Stat Stop Close Figure 2 2 13 The QC window for calibration 16 TRIUMPH X SPECTO USERS MANUAL Protocol Builder To facilitate establishing a protocol especially the right ROR Triumph SPECT set up has implemented an interacti
67. phy data set with different isotope energy windows or any number of different tomography data sets can be processed each with a reconstruction request 1f the Do reconstruction checkbox 1s marked passed to the Batch Processing screen When all ColorSPECT processing jobs are complete the user can switch to the Batch Processing screen to start all the reconstructions in one batch job 59 TRIUMPH X SPECTO USERS MANUAL Generate UCT ColorSPECT has the ability to generate Uniformity Correction Tables UCT s with any energy window if the necessary list mode flood data has been acquired with the required collimator and isotope UCTs are used to normalize the tomography data that is to correct for any pixel to pixel variation in gamma camera sensitivity and to account for the collimator sensitivity response across the FOV For instructions on how to acquire UCTs and OCs Quality Control images please reference Chapter 3 of this section Flood acquisitions with a given collimator and isotope can be acquired with list mode enabled and with such list mode data any number of UCT s for this collimator isotope pair can be generated with any energy window For instructions on how to create arbitrary isotope energy windows please reference the ColorSPECT section of the appendix in this chapter These UCTs can be generated and applied to list mode data AFTER the original data has been acquired To generate a UCT in ColorSPECT proces
68. r a particular genotype be associated with the patient name e g BalbC J 383 SCID_ApoE KO 77 Sex Sex of the animal contains a drop down list of male default and female Weight weight of the animal at time of imaging DOB Date of birth of the animal the drop down list is a calendar Description Any further genetic and or physicial modification be recorded in the description window e g prostectamy performed 9 24 08 Add button this button add the established patient into the study history list Study history This is not a user input section It contains all the studies established and or performed under this study It is by default sorted by patient but can be resorted by clicking on the desired column There are three interactive button that links the history page to the scan window which allows users to repeat the exact scan to view the performed scan or to remove the scan TRIUMPH X SPECT USERS MANUAL Protocol Protocol window contains a total of six sections defining the acquisition condition from all necessary aspects of nuclear imaging ee Acquiaition Tite frac 5 Aganin Loma Eds Figure 2 2 2 Protocol Set up Window l Protocol List Similar to the Study window the protocol list is a explore style window that allow you organize view edit or remove your protocols 2 Protocol info Protocol info panel sets the critical identifiers of the protocol
69. reconstructed data and are usually exported from Triumph SPECT data export function into C Interfile folder Under Select any one of the acquired Interfiles click the browse button to open a browse dialog window Locate and select the Interfile header file to be reconstructed Once the Interfile has been selected information about the study will automatically be displayed on the screen The desired name of the resulting reconstruction file must be entered under Save Result file as choose as a img file Click the browse button in this field and a dialog box will appear Here select a file path and name for the reconstruction file The Radius of Rotation ROR of the study must be entered under ROR mm This information is normally available in the Study ID name and needs to be filled out in units of millimeters mm When these last two fields have been filled out the reconstruction is ready to be started Click on the Reconstruct Peconstue button to start the reconstruction A progress bar will appear at the bottom of the screen and will track the state of the reconstruction When the reconstruction is complete a message showing the location of the saved resulting file will be display Four optional controls can be modified in the Single Reconstruction mode if so desired The Detector mode is normally set to the default value of the user s 48 TRIUMPH X SPECTO USERS MANUAL
70. removed defaced or altered This limited warranty is not assignable by Purchaser except as incident to a financing arrangement or other special transaction the Seller has approved Geographic relocation of a product during the warranty period may result in exclusion of the product from further warranty coverage ANY MODIFICATION UNAUTHORIZED INSTALLATION SETUP OR SERVICING REPAIR OF THE PRODUCTS BY ANY PERSONS OTHER THAN SELLER OR SELLERS AUTHORIZED REPRESENTATIVE SHALL VOID THIS WARRANTY Index A PP o o A 50 AAPP a E a tad cassia shee aug escuese a E 42 Acquisition Dynamic SE EG ACQUIS WOM esencia A Masleende ects pr c ao 6 AUG Ee acquisition iodo 4 Tomographic SFEC T acquis artos ota 8 Anesthesia esei Aa 49 Animal DOS IN aE aaa 51 B BACH TIES iiair aa A 71 Batch processiNhg ssori EENE a EEE EKKE aE NaN 39 Bullseye 3D analysis sasta RRE 65 C So A 53 Cardiac AC UNS UCONN css 52 Cardiac Gated SPECT sscnisrioni das 49 COlNIMator ani 43 46 COl SPEC T sind 70 78 Stale DIOLOCO sacada E S O E EE 43 TOMO Protocolo 44 COMPOSE TEPOV sioria nn A 65 CG otegis rallo socias E E 21 o A 18 Customer SUDOR nte 79 a jf TRIUMPH X SPECTO USERS MANUAL D Dataset level adi 3 BTE e tai id 59 DVMAMIG TODO Mai AS E tal 15 E CG OAS cnica AS iaa 49 ECG MONTO ata suiueceestedsatancavecscevedsetasseuasvacvedsetaasauectarvateesiaxtsseantaads 50 ECG timing WIN d OWN rele eee 55 do 16 0 1 y e AA o O O EET EET ENEE ARDA 16
71. riumph SPECT Scan Data Viewer GAMMA MEDICA IDEAS Pav PICA E LEE MEDCAL Prabssal Hani Sean iD Ses Hada Soin Tita Sean Description zi P tilludaos dai api fhe hale ab dl Sed Fo fel Super Phantom Ginie Kanye High amp ice bbdd ie Toma 4 24 08 41233 loan rada whet 7 SUPPL APN TOM akren tang spinal MH AFERAGE Ton Sul PS Ath adan red ahead 7 Sune hanno leen prep april EEEE Toma Sul AS 10 30 0 View Sean Chom Figure 2 3 27 Image Database in the data viewer To view select the study in the left the window and the particular scan in the right then click View Scan button The chose scan will be presented For detail contents in the window please reference the previous section Triumph SPECT Data Viewer GAMMA MEDIOMDEA gt Siudy Parmele Hate Milut Study Hama Penin ia Operator d Diii Pinar fion iano irsin Faan Hare Supe Panto Proteced Hare Geet iaje ipea Garey Mode Hore Ei N Hora AF Garl Pal Sy arn Goan Hoe Tama Sem Tepe Arpa Scan Descrpion dead el Murba of paean l Manoel MG Mision Y na Foaia 15 Frias T 15 Spend hat Tre 424 006 9 50 02 Pm Scan Diasbor ES Ha of Pregecions Per image 64 nonpa feiim oes mikar HERNIA Time per Projecbon 15 secs Coma Hind 1 laa Te F Erm Wi i hal Figure 2 3 28 Data Viewing Window the red arrow points to the play control bar 36 TRIUMPH X SPECTO USERS MANUAL Data Import and Export Projection data are exported and imported through the data viw
72. s 33 TRIUMPH X SPECTO USERS MANUAL Triumph Please use the hand controller to position the end point of FOY to the laser point and click Next Figure 2 3 25 Step 2 message for sprial scan At the request user can use the hand controller to define the end point alternatively Back button can be hit should user wish to change the starting point Upon setting the end point hit Next The regular message box for Camera Details will be presented User should follow similar routine to fine position the object except do not worry about the bed position it won t matter After all the parameters are set and user clicks Done the scan will start the gantry will first move the animal bed to the point so the start point will be at the center of the FOV then the cameras will be moved to ROR then gantry will rewind to fixed starting angle All progresses can be monitored in the same way NOTE The bed only moves inward Therefore the starting position should always be bigger than the ending position Otherwise movements will be all wrongfully operated NOTE The moving step is calculated based on the total moving distance defined by user and a hard coded rule to cover the entire FOV within 180 of gantry rotation Dynamic Tomo Scan To performe a dynamic tomo scan the Dynamic Tomo should be selected during protocol set up The repsective setting window will appear in the protoco
73. s are found but files for this particular collimator are not found e g PHOS is found but not the exact collimator match PH10 The collMatchFlag in the spect ini file may be the source of the problem Alternatively there may not be any GeoCal files for this particular collimator Please contact GM I customer support if this error occurs X Geocal files doesn t exist For this particular ROR 12 mm at CiltestiExpts 11 27IGeocal The error above is displayed when the interpflag 0 in the spect ini file and the GeoCal file s at the particular ROR are not found The user can either acquire and process GeoCal data at the desired ROR or set the interpflag 1 to interpolate extrapolate between GeoCal points Warning A Extrapolation is greater than 5 mm Do vou still want to continue The warning above 1s displayed when the GeoCal extrapolation 1s greater than the value that specified in the spect im file by the parameter maxextrapolation mm This message is simply a warning and can be ignored in most cases though large extrapolations can result in poor reconstructions Reconstruction Error The error above is displayed when an internal error in the reconstruction jJls TRIUMPH X SPECTO USERS MANUAL occurs unrelated to the GeoCal file s or anything on the system Please contact GM I customer support if this error occurs Reconstruction Error The error above is displayed when the reconstr
74. s the UCT list mode data as normal static list mode data making sure that the Generate UCT checkbox is marked Once the Process button has been pressed the UCT will automatically be generated in the proper directory usually D LumaGEM Calibrations If a UCT with the same collimator isotope energy window already exists a warning will be displayed asking whether the user wishes to overwrite the original UCT not recommended In addition a warning may occur if dead pixels 1 e pixels with zero counts or low statistics pixels 1 e pixels with counts lt 50 are present in the UCT list mode data If any such dead or low statistics pixels occur in the generated UCT GM I recommends trying to acquire the UCT again with a larger number of counts Generate Spectra Cd109 ColorSPECT can generate TY Ament spectra file s from both A Tc99m static and tomo list mode data This can be useful when trying to determine Normalized Counts which isotopes energy 2 0 3 windows can be distinguished by the oi P aa gamma camera s in o SA a 0 20 40 60 80 100 120 140 160 180 200 220 240 260 280 3 question see Figure Energy keV 2 4 13 To generate Figure 2 4 13 Example energy spectra acquired from various spectra file s check the isotopes In 111 Tc 99m Co 57 Am 241 and Cd 109 using Generate SPECTRA eee mance Mone checkbox in the ColorSPECT screen The adjacent drop down me
75. tation for a full tomo scan For a single camera system the minimum is 360 For a 2 or 4 camera system the minimum is 180 and 90 respectively e Num of Proj number of projections images to acquire over the rotation angle defined In order to object optimal sampling it is recommended that 64 projections be acquired over 360 i e for 4 cameras 900 and 16 projection is recommended Acquire projections more than recommended will be oversampling and unnecessary e Time per Proj how long each projection should last it is recommended that 5 sec or longer to be entered TRIUMPH X SPECTO USERS MANUAL e Compensate Decay 1f checked time for later projection would be adjusted based on radiation decay of the isotope to match the total activity of the first acquisition The Helical scan is tomo scan with constant axial bed movement The detail setting window is similar except that the angel of rotation 1s no longer changeable To ensure adequate sampling full round rotation has to be achieved In addition to detail setting manual bed positioning is needed during an actual scan please follow the instruction in the next section when actually perform a spiral scan 6 Isotope info The last and also very critical parameter field for a protocol is isotope s more than one isotope can be added to the list meaning more than one isotope can be imaged simultaneously Each isotope has more than one choice of energy windows Bigger window
76. terests there is only one organ can be physical centered in the FOV This field is similar to patient position serve only for reference and do not orchestrate any gantry movement Activity Administration This is an additional feature that 1s effective only when user connect a Triumph compatible infusion pump with the gantry for installation instruction please reference related hardware manual Once properly connected the pump will start injecting radioisotopes at a pre time with pre set speed and total volume before or during image acquisition The contents in all the columns are self explanatory so will not be listed in this paragraph If there is no pump connected the contents in this window will not affect any gantry function Operator an optional field for the names of investigators Description a free text field to record experimental notes Save Listmode if the toggle box is check list mode data will be saved in addition to the normalized projection for future analysis using colorSPECT see FLEX _Triumph manual Animal Status Triumph gantry is equipped with animal monitoring sensors and once connected to the animal with proper probes the following animal vital signs can be monitored in real time with or without image being acquired o Temperature through a rectal probe o Heartbeat through 2 EKG needles o Breathing through an external pillow sensor Based on the type of vital sign chosen in the top drop dow
77. tice to give a descriptive name for the Study Name and to use the same Patient Name and Patient ID that was used in acquiring the data Next from the Collimator drop down menu select the collimator that was used to acquire the data It 1s important to choose the correct collimator as an incorrect choice will severely distort the resulting data From the Isotope drop down menu choose the desired isotope and energy window There is no inherent constraint in the choice of isotope and energy window To obtain the best possible images each projection should be uniformity corrected In order to perform the uniformity correction the Uniformity Correction Table UCT must exist for the selected 58 TRIUMPH X SPECTO USERS MANUAL isotope and energy window however this UCT can be acquired after acquisition if necessary ColorSPECT has the ability to generate UCTs with any energy window if the necessary list mode flood data has been acquired with the needed collimator and isotope Generating UCTs from list mode data is discussed further later in this chapter If the required UCT is not available a warning message will appear and the user can choose to continue processing the static data without a UCT not recommended or abort the static processing and acquire the necessary UCT which can always be acquired and applied post tomo acquisition Once the Choose Color SPECT File field has been entered the Number of
78. ting parameter in the detail setting window please reference the feature introduction in the previous section The Phase 2 will be activated once phase 1 1s all filled After the parameter 1s set the dynamic scan can be performed in the scan window in the similar way as the static scan If Pause is enabled a check point window will appear in between phases awaiting user s keyboard action Tomographic Spiral Scan To perform a spiral scan Helical instead of Circular mode needs to be selected in the Tomo settings during protocol set up After Helical is selected the window will be formatted to remove the Rotation Angle for it will be automatically established Tomo Settings Helical Circular Rotation Angle Num Of Proj 64 bel Time per Proj sec 15 Compensate Decay Add Figure 2 3 23 spiral scan setting When performing a spiral scan select the spiral scan protcol in the scan window position the animal object onto the bed in the front deck then click on start button a different positioning guide will show up Triumph Please use the hand controller to position the starting point of FOY to the lager point and click Next Figure 2 3 24 Step 1 message for sprial scan At the request use the hand controller to move the bed so the starting position is aligned with the front entrance laser then hit Next The second request will show up asking for where it end
79. tware does not allow operations to occur out of order or on non parallel steps Triumph SPECT and FLEX SPECT are independent so acquisition and processing on different set of data can be performed at the same time Triumph SPECT Triumph SPECT is a protocol based data acquisition and database management software It is configured to control SPECT image acquisition with Triumph gantry consisting up to four gamma cameras From the graphical user interface there are five categories of functionality that guide user to optimize data acquisition e Set up Set up window is the starting point where users establish their database It contains two tabs protocol and study which are the two indexes used in the program to manage all imaging data Protocol defines camera and gantry settings including collimator type scan type camera position acquisition time isotope and engeryg windows Study manages experiments and patients animals e Scan Scan window starts and stops a scan It starts by selecting pre defined study patient and protocol Scan window also has cross action buttons allowing users to modify or create new parameters studies and protocols e Calibration Calibration window contains control panels for three standard system maintenance procedures Gantry calibration for mechanics camera calibration for detector uniformity and quality control flood image acquisition tabs In the top menu bar there is also a tool for
80. uaaveau 50 PF INTCR Vall WING OW ii ion 56 S SAIN G O a deaeeaccccseteniweseescteceaniace 61 SEL ROR wave ce kee oie ee el a el 10 SINGIS FECOMS UU CTIONN cosas 30 BOTT ALS e Camera ti o OTe ner Pe a a A en ma O o ia 59 A wer nanel rhrertter lenin a ener erty inane 17 nn o A E T 68 75 SpiralSPECT ACUSA la aiii 33 FRECOMS IUCN do ld ne e o A e ae sie 38 Standard reposa de eee 65 ci A ne St err eT Re oe Ene ee a ee or ree eee ee rer eee eee ee 15 Study level Beemer terete ees ett 3 A teen ee te aces Detiree cave aceeeeb eos EE 3 SV MAD SPEC We Soca ee 25 26 T Thermal LU da eee 51 Mco AAA vans cessaedsscasceueedesdessaces cevesicsdavesdeces E 20 63 TINA CUM CU dias 14 TMPOUDIESNOOUING sii custusiaubeduauadudeucarsuec toned acucen aucune 73 U Uniformity correction table UC siccisesccceces cicericeacesacec Sens iia 23 47 V VISI eVel an ia as 3 W WAN Oir ias See Troubleshooting Ac ave Ges secteur a a a aa aaa 79 79
81. ual list mode datasets The tomo protocol 1s used to process tomographic projection data that consist of many views of the object being imaged over various angles The two types of protocols are processed in a similar manner in ColorSPECT but this manual will treat them as different for the purposes of describing how to process them To enable list mode acquisition the user must open the file D LumaGEM acqenf ini and set the parameter bLMFile to be 1 as shown in Figure 2 4 9 To disable list mode acquisition the same parameter must be set to 0 Please disable list mode acquisition when finished acquiring list mode data as list mode data can generate many gigabytes of data and may fill the user s hard drive very quickly if left enabled Static Protocol To process a dataset using the static protocol select the list mode file to be processed by clicking on the browse _ button of the Choose Color SPECT File field A dialog box will appear in which the user can search for the desired list mode data List mode data needs to be extracted out of C gamma savelistmode directory All the bin files are named with Triumph SPECT special code and user will need to remember the data and time of the acquisition to pull out the correct file 55 TRIUMPH X SPECT USERS MANUAL PA FLEX SPECT Version 1 0 6 a E pTM _ ON FLEX SPECT Reconstruction mamma mebica IDEAS 2 al Please select the color SPECT study and cl
82. uction 1s stopped by pressing ctrl break the reconstruction stops only after the completion of the current iteration Warning LD The reconstructed image had negative pixels 25 pixels and wrap around problems 34 pixels which were corrected The warning above is displayed if the reconstructed image had negative pixels and or 16 bit wrap around problems during float to integer scaling This message is simply a warning and can be ignored in most cases Warning The warning above is displayed when the result file added in one of the studies has already been used in one of the previous studies e g if the user used test img as the result file for study 1 and attempted to also use the name test mg for the result file for study 2 Make sure all result file names are unique in batch processing mode 72 TRIUMPH X SPECTO USERS MANUAL Warning There s a potential over write of the Following Files in your studies CiitestiExpts 11 2711010 _Resolutionitestl img in Study 1 CilbestiExpts 11 2711010 Resolutionitesti img in Study 3 CiitestiExpts 11 2711010 _Resolutionitestz img in Study 6 Click Yes iF you dont mind over writing the Files or Wo iF you wish to abort the reconstructions The warning above will be displayed after the user clicks Reconstruct from the Batch Processing screen if there is a chance of overwriting some files that already exist Press Yes to overwrite the files or No
83. urce isotope is the isotope used during UCT flood acquisition Target isotope is the additional isotopes with similar energy peak profile E g I and co can both be the target isotope of Tc 3 Total count value is recommended to be at least 10000 kilo for UCT and 3000 kilo for QC NO m Ganley Cabivation UET 0E Colimator priv i Seco lreiepe Target iretur liotepe Mama 1i The linbapa Mama Cot Lal Enen Window 20 F Energ Window px x add neme Chom Source lactopa N Seaca Intope Enang Targat hetope Mame Targal Inatope Ena Thiim Hi Coa 20 Total Counts lor QE 3000 Tatal Counts Kato 10000 l E Run U Delap Tinn jhh Generate uiput For Cameras Ei z 3 4 ICT Pragr rs Stat Stop tome Figure 2 3 34 UCT window 40 TRIUMPH X SPECTO USERS MANUAL After proper parameter input and proper source positioning click start to start acquiring the flood image UCT will run automatically after the acquisition UCT is recommended to be recalculated at least every month for electronics do shift with time which will affect pixel response to signals If the QC tab is checked UCT will be followed by a QC acquisition and noise calculation if the run QC is checked QC can be run independently anytime users want to check if the camera uniformity is still good Unlike UCT QC should be done more frequently preferably every other week during a c
84. utomatically run all the modules to their limit switches and start calibration process Triumph SPECT Calibrations GAMMA MECA DA A Banter Lalbratron UCT ac Bed Porton 32 653 Gantry Angle 11 272 Garry Calituation Status Stat Chose Figure 2 3 32 Gantry calibration window Upon finish a gantry is calibrated successfully message will show up in the information box NOTE Please remember your camera setting prior to the gantry calibration for modules will NOT be returned after calibration All modules need to be repositioned 38 TRIUMPH X SPECTO USERS MANUAL Camera Calibration UCT and QC The UCTs Uniformity Correction Tables of the gamma cameras must be updated on a regular basis due to a small amount of drift that occurs within the electronics over time To calibrate the cameras a planar image of a uniform flood source must be acquired The calibration is source and collimator specific so there must be a calibration file for each isotope and energy window While all SynapSPECT use an intrinsic image 1 e an image acquired with a point source without collimators single pinhole and parallel hole SPECT require extrinsic images i e images taken with flood phantom with the exact collimator Once the necessary images have been acquired a UCT will be automatically generated After the UCT has been generated a QC will run to ensure proper functioning of each camera Uniform sour
85. ve Protocol Builder this window can be invoked by the clicking the pencil icon in the top menu bar or clicking the Builder button in the scan window right by the Protocol drop down list The builder window looks very much like the camera detail window except the window title s clear indication It has persistent windows for all activated camera heads the energy spectra and count rate window with all cameras plotted coloer coded On the right is the information panel user will need to fill out Triumph SPECT Protocol Builder GAMMA MEDICA DEAS gt Camera 43 Energy Spectra lectope Setting Isotope Energy Windom Gantry Seting Colimator 4 1 f e ROR mm 0 oe t i 7 100 w 300 500 FOY mm Persistence Time UCT mort Bed Position 29 048 Set Bed Position IA 394 Cancel Create Protocol Figure 2 2 14 Protocol Builder window Isotope Setting Isotope and energy window can only be input one at a time Gantry Setting Collimator type needs to be put in for ROR input to be activated After activation user can view the current ROR in the right cell of the ROR panel By entering numbers in the left cell and hit set ROR button user can reset the camera to a new ROR and the FOV will change instantly so would the persistent window images Gantry Setting Bed position and starting gantry angel can also be set in the similar way persistent windows will change base
86. w have been counted and binned into their corresponding estimated physical detector pixel The ColorSPECT feature thus allows the user to re process acquired data using any desired energy 54 TRIUMPH X SPECTO USERS MANUAL windowing after the data has been acquired and at the user s convenience This type of post processing is not possible with frame mode data The primary use of ColorSPECT for the typical user is to apply different and or multiple energy windows to the same acquired data set see Figure 2 4 8 for an example and thus the term ColorSPECT to describe this feature which allows the user to create color like SPECT reconstructions along the lines of standard television palettes that use three primary colors red green and blue to create any color combination The use of ColorSPECT requires that FLEX SPECT be installed on the SPECT or CT acquisition host computers in order to have access to the pertinent gamma camera calibration files ColorSPECT may be disabled on computers that do not have access to these files for more information on installation please reference the appendix If ColorSPECT is enabled the user can access it by selecting the ColorsPECT option in the Select mode drop down menu There are two protocols currently supported in ColorSPECT static and tomo which can be toggled between using the Protocol drop down menu The static protocol is used to process individ
87. with and without GDRC enabled Only one of the tomo dataset Interfiles needs be selected the others will automatically be located as long as they reside in the same directory as the selected Interfile Click on Merle to start the reconstruction 25 TRIUMPH X SPECTO USERS MANUAL Pr FLEX SPECT Version 1 0 5 l ee _ o FLEX SPECT Reconstruction Amma menica ineas gt _ al Please choose your files and parameters below and click Reconstruct Selca mode Single Reconstruction ota ETT Select any one of the acquired Imterfiles Study M Stehy DateTime Focal length mm Hum Projecilonsj mgle Colllmatar Pinhole Size mmi Nmejprojeci on jace Spiral slep size fim io Begin reconalrucdiion al interiile i Ho of interfiles lo be considered an Fi Save Hesull lile as choose as a img file i ROR mm Detector mode Duaal a GPR Dizahie x Humber of lterailons E Number of Subsets d HMeconstruct Figure 2 4 7 Single reconstruction of a spiral orbit Spiral data can be reconstructed into a rectangular size or zero padded into a cube Rectangular reconstructions require less disk space but may not be viewable by all images viewing software In the parameter file spect ini spiral_cube can be set to 0 rectangular or 1 cube For more information on parameter files please reference the appendix of this section Batch Processing Batch processing is a convenient t
88. ximate the combined collimator detector PSF This geometric approximation proves to be quite accurate and greatly shortens the reconstruction time compared to using an empirical model of the PSF The four parameters as shown in Figure 2 4 3 that characterize the collimator are the pinhole aperture the tunnel depth the surface to aperture distance and the full acceptance angle The pixilated detector is characterized by its intrinsic pixel pitch Please note that at present pinhole penetration and detector depth of interaction are not directly taken into account by SuperSPECT GDRC can be enabled or disabled in FLEX SPECT by selecting GDRC in the drop down menu GDRC is currently supported for single pinhole reconstructions of both circular and spiral orbits GDRC enabled is somewhat slower than GDRC disabled due to the increased computational requirements of modeling the collimator detector PSF GDRC enabled is 50 TRIUMPH X SPECTO USERS MANUAL recommended in cases in which the user wants to achieve maximum spatial resolution and is not overly concerned with reconstruction times Reconstructions with GDRC enabled take typically three times as long as GDRC disabled reconstructions with the same number of iterations Spiral SPECT Reconstruction Once a SpiralSPECT tomographic dataset has been acquired select the Single Reconstruction mode and select Spiral under the Orbit drop down menu Three new fields
89. y correction the Uniformity Correction Table UCT must exist for the selected isotope and energy window however this UCT can be acquired after acquisition if necessary ColorSPECT has the ability to generate UCTs with any energy window if the necessary list mode flood data has been acquired with the needed collimator and isotope Generating UCTs from list mode data is discussed further later in this chapter If the required UCT 1s not available a warning message will appear and the user can choose to continue processing the static data without a UCT not recommended or abort the static processing and acquire the necessary UCT which can always be acquired and applied post acquisition 56 TRIUMPH X SPECTO USERS MANUAL Finally select a name for the generated Interfile by clicking on the browse button in the Save File field which opens a dialog box in which the user can navigate to the desired directory and select a file or type a new name Reconstructions are not supported under the static protocol and in general the Generate UCT checkbox should be un marked unless a UCT is to be created A spectra file of the static list mode data can be generated by marking the Generate Spectra checkbox for more information please reference the Generate Spectra section of this chapter Once all of the fields have been entered press the Process button to begin processing The status bar at the top of the screen

Software Manual for Acquisition and Processing of SPECT images

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