lick suppression
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1. 1 0 In this example only one box is described in the Hardware Configuration so Figure 3 8 will appear next If more than one box is in the Hardware Configuration then Figure 3 9 will appear Figure 3 8 Send Start Command Screen for Single Box Configuration MED ASSOCIATES INC LICK SUPPRESSION Figure 3 9 Send Start Command Screen for Multiple Box Configuration In both cases Figure 3 8 and Figure 3 9 the screens are where the researcher decides to either load more boxes send a start signal to boxes that are already loaded or enter the MED PC run time environment without sending a start signal by selecting I am finished with the wizard This option results in the screen shown in Figure 3 10 Figure 3 10 The MED PC Run Time Screen File Configure View Macros Help lole e Program 121212 15 5 7 8 15 1 010 SoftCR Code 1 00 SessionTime 5 00 Value 20 00 Shock Length MED ASSOCIATES INC LICK SUPPRESSION Viewing Changing Variable Values Before a start command has been issued any variable may be changed on the MED PC run time screen Simply highlight the value to change and then enter the new value Once a session is in progress change variables by selecting Configure Change Variables or click the 4th tool bar item AX In the lower left hand corner of the Change Variables window find the Display Data f2. Once the commands are in the macro it is easy to create a number of macros with the macro editor The following example illustrates the process of loading Box 1 and changing the Session Time to 10 minutes To begin open MED PC and going directly to the run time screen Close the load wizard if present Before loading or opening the procedure click Macro on the main menu and select Turn On Macro Recorder or click the 8th tool bar item with the cassette tape icon on top A note on the bottom of the display indicates that the recorder is running Open Lick Suppression mpc by clicking Files Open Session Change the variables using any of the methods described above When all settings have been made turn the recorder off again by using the main menu or tool bar Save the macro with a distinctive name The example in Figure 3 14 was named LS 10min Session mac since the Session Time was changed to 10 minutes Figure 3 14 15 10min Session mac LS 10min Session MAC Notepad File Edit Format View Help LOAD BOX 1 SUBJ 0 EXPT GROUP 0 PROGRAM LICK SUPPRESSION SET session Time min VALUE 10 MAINBOX 1 BOXES Once this macro is built use the macro editor to make simple changes such as replacing reward or correct lever values Review the Help file on screen or the MED PC User s Manual for more information on macros and the features offered A START command or message box followed by a START command could be added to the macro
3. also be dependent on the Subject Experiment and Group name provided in the MED PC load wizard Within each data file the headings are created for each Subject Experiment Group Box etc see below Data files may be opened with note pad word pad or any word processor or spreadsheet however be sure they are always saved unformatted in case a data extraction utility such as MED PC to Excel might ever be used Data file formats are explained in detail in the MED PC User s Manual
4. also determined by the Hardware Configuration Running the Hardware Configuration software utility that accompanies MED PC sets the Hardware Configuration Its purpose is to assign the inputs and outputs on the interface cards in the interface cabinet for each task controlled by MED PC The particular type of interface card that is supplied in the interface cabinet may vary please refer to the User s Manual provided for instructions on how to configure the type of card that is in the cabinet A valid Hardware Configuration must exist in order for MED PC to interface correctly with the MED Associates Inc hardware This means that one should take the time to create a valid Hardware Configuration before attempting to run the procedures included in this package Should there be any problems the staff at MED Associates Inc is available to answer any questions that may arise Please e mail us at support med associates com with a detailed description of the problem or desired goals so that concise and detailed information may be provided The Lick Suppression procedure is designed to be as easy to use as possible MED Associates Inc understands that researchers do not have the time to devote to programming and hardware design and for that reason we have undertaken that burden for you We sincerely hope that you are satisfied with the products and services we provide and look forward to meeting your future experimental needs as your research progr
5. LICK SUPPRESSION MED STATE NOTATION PROCEDURE SOF 700RA 22 Manual DOC 129 Rev 1 1 Copyright 2009 All Rights Reserved MED Associates Inc P O Box 319 St Albans Vermont 05478 www med associates com Trademarks MedState Notation MED Associates Inc Registered Trademark MED PC MED Associates Inc Delphi Borland International Inc MED ASSOCIATES INC LICK SUPPRESSION TABLE OF CONTENTS Chapter YQXY ooa 1 1 Overview of the 2 Control Variables 2 Chapter 2 3 Getting P 3 Software InstallatiQni siisii aaan ka 3 Backing Up the SoftWale 3 ine td Lek eda RR LE XR GE rn Ea DER AE deeds DE ER 3 Chapter 3 iini 4 Beginning amp Running an Experiment 0 0 0 4 Translating the MED PC mpc 4 Using the MED PC Load Wizard 5 Viewing Changing Variable Values 10 leger 12 Modifying the MedState Notation nee 13 Chapter 4 iiec seconde ion inda and wa cw ww wa wa dr d Rc rar 14 Understandin
6. am evolves Overview of the Procedure The Lick Suppression procedure allows the animal to freely lick from the sipper tube After a certain number of licks defined by the variable Fixed Ratio Value the animal is given an aversive stimulus The duration of the aversive stimulus is defined by the variable Shock Length The variable SoftCR Data Array determines whether or not an array containing SoftCR data is included in the data file Control Variables Variable Name Default Value Session Time minutes 5 Fixed Ratio Value 20 Shock Length seconds 0 1 SoftCR Data Array Yes 1 No 0 1 CHAPTER 2 Getting Started Software Installation Please refer to the MED PC User s Manual for a complete guide to installing the MED PC software building a valid Hardware configuration with the Hardware Configuration utility and opening and compiling a MSN procedure in the Trans IV utility To install the Lick Suppression Procedure insert the CD into the CD ROM drive and click Install the Lick Suppression Software The procedure is copied into the indicated folder Backing Up the Software Med Associates strongly encourages creating backup copies of the programs in case of disk failure Having copies of the original programs may be useful in the future should modifications be made to the existing programs MED ASSOCIATES INC LICK SUPPRESSION CHAPTER 3 Beginning amp Running an Experiment Translati
7. g the Data Files 14 MED ASSOCIATES INC LICK SUPPRESSION iv CHAPTER 1 Introduction The purpose of this manual is to give an explanation of the MED State Notation Procedures that comprise the SOF 700RA 22 Lick Suppression Procedure The files in this package can be found on the disk provided by MED Associates Inc These procedures are intended to be run in MED Associates MED PC software The latest version of MED PC gives researchers the ability to use pre programmed procedures such as these to make hardware control and data collection easy These pre programmed procedures can also be modified to meet the evolving demands of a research protocol Again it is the intent of this manual to explain exactly what these procedures implement and provide guidance into how to interpret what the program code achieves in order to let the user determine how to modify them to match their research protocol demands The manual provides some examples of editing and modifying the procedure s programming code The manual also defines the elements in the raw data file produced by these procedures In addition to this manual refer to the MED PC User s Manual for the installation of the MED Associates interface drivers the MED PC Software and the Delphi Compiler Also refer to the User s Manual for instructions on developing a Hardware Configuration Data file structure file saving format and other related options are
8. it was left off here so changes could be verified before starting the procedure MED ASSOCIATES INC LICK SUPPRESSION Modifying the MedState Notation Code Permanent changes to the Lick Suppression procedure can be made to the MedState Notation code To make the same change to the Session Time as shown above do the following Open Trans IV and select File Open to place Lick Suppression mpc into the text editor Scroll down to approximately line 63 note the line counter in the lower right hand corner of the editor to reveal the code shown in Figure 3 15 Figure 3 15 Lick Suppression mpc Line 63 FEN TRANS IV C MED PC IV MPC Lick Suppression mpc ES File Edit Search Options Translation Window Help 0 001 SET 0 Hf ii 20 2 0 1 3 1 82 Change A 0 5 to A 0 10 and save the changes with the same or a new file name such as LS_10min_Session mpc Remember if creating a new mpc file name and are using a macro to load boxes the file name in the macro also must be changed Translate and compile the new or changed file as described previously and run MED PC IV Use the Change Variables screen to view confirm the new values CHAPTER 4 Understanding the Data Files Data can be saved manually by selecting FILE SAVE DATA MANUALLY or FILE SAVE DATA FLUSH The file name that is used to save the data in depends on the option that was chosen in the Hardware Configuration Utility and may
9. ng the MED PC mpc File Programs written in MedState Notation must be translated using Trans IV before they can be executed in this application Open Trans IV icon and select Translation Translate and Compile Select the program s to use for the experiment and click Make Click OK to start the translator and it will automatically parse the MedState Notation and then open to a DOS screen to compile the Pascal code Depending on the speed of the computer each of these steps may not be seen If any problems are encountered during this process refer to the on screen help menu or the MED PC Version User s Manual or contact MED Associates Inc for assistance Figure 3 1 Trans IV Control Panel for Translating and Compiling MedState Notation Code th Specify Files to Translate Lick Suppression mpc Build No Trans Exclude wv OK X Cancel Help MED ASSOCIATES INC LICK SUPPRESSION Using the MED PC Load Wizard MED PC is designed to help the researcher run an experiment by guiding selection choices through its Experiment Loading Wizard This section will describe how to initiate the Lick Suppression mpc application however the following steps that will also apply to all other mpc procedures Open MED PC and the MED PC Experiment Loading Wizard s Welcome screen shown in Figure 3 2 will appear Figure 3 2 The MED PC Loading Wizard Welcome Screen To avoid this load wizard deselect the checkb
10. ox labeled Run this experiment automatically when starting MED PC Close this screen by clicking the Close button Closing this screen immediately reveals the MED PC Run Time Screen shown in Figure 3 9 If the choice to continue with the Loading Wizard is made then click the Next button MED ASSOCIATES INC LICK SUPPRESSION The Box Selection screen will appear next as shown in Figure 3 3 From this screen the researcher chooses which boxes will be used in the experiment Select the boxes that will run the experiment by clicking in the radio button next to the box number The figure shows that the Hardware Configuration included only 1 box which was selected Click Next to continue Figure 3 3 The Box Selection Screen The Select a Procedure screen appears next as seen in Figure 3 4 This is where the application to be run is selected The screen displays a list of all the currently compiled procedures Select the desired procedure and then click Next Figure 3 4 The Select a Procedure Screen MED ASSOCIATES INC LICK SUPPRESSION The Enter Experiment Data Screen should display next as shown in Figure 3 5 The purpose of this screen is to allow annotations to be added to the data file that is produced by MED PC These annotations will help identify the Subject Experiment and Experiment Group upon which data was collected Comments can be added here as well and the data file can be given a customized file name to hel
11. p identify it from other data files Enter the information desired and click Next Figure 3 5 Enter Experiment Data Screen e Subject 1 Subject Expe riment Lick Suppression 1 Group Comments Lick Suppression Experiment Optional Custom Filename LS_Subiect _Group1 The next screen to appear is the Review Choices screen as seen in Figure 3 6 This is a method of confirming that the information received from the Box Procedure Selected is correct If it is not correct select Previous and edit the data If it is correct select Next Figure 3 6 Review Choices Screen Review the data below Boc 1 Procedure LICK SUPPRESSION Subject Subject 1 Experiment Lick Suppression 1 Group Group 1 Comment Lick Suppression Experiment Filename LS Subjectl Click Next to finish loading the box or Previous to correct errors MED ASSOCIATES INC LICK SUPPRESSION The Alter Session Parameters Screen shown in Figure 3 7 is the next screen to appear and is an important screen for the researcher The Alter Session Parameters screen allows the researcher to alter the parameters by which a procedure executes The Send Start Command Screen appears next The options available on the screen vary depending upon how many boxes are described in the Hardware Configuration Figure 3 7 Alter Session Parameters Screen Session Time Fixed Ratio Value Shock SoftCR Data
12. rom Box display and choose the chamber s to modify By clicking additional boxes in the Additional Boxes to Update section changes made to a single box are automatically loaded to all of the selected boxes Figure 3 11 Changing Variables Screen Displaying Variables from Box 1 B D E Named Vars PAUTAS 0 000 Sam 0 000 0 000 _Nowed Var F k U Var 0 000 0 000 0 000 0 000 0 000 K L M N 0 000 0 000 0 000 0 000 0 000 Befresh P Q R 5 T 0 000 0 000 0 000 0 000 0 000 Issue y W Y 0 000 0 000 0 000 0 000 0 000 Close a 0 000 B Help Display Data from Box Additional Boxes to Update B from Box 1 0 000 74 Select All Deselect All The value of any simple variable may be viewed from this screen by clicking an array on the table and each element in that array can be viewed as shown in Figure 3 12 To change a value simply highlight and replace the value in the lower right hand box or use the up down arrows to increment by 1 Click the Issue button for the change to take effect Click Named Variables to produce the display in Figure 3 13 Change variables here as needed 10 MED ASSOCIATES INC LICK SUPPRESSION Figure 3 12 Displaying Array A from Box 1 Displaying Array A from Box 1 11 MED ASSOCIATES INC LICK SUPPRESSION Macros The simplest way to initially create a macro is to record keyboard functions while performing the steps manually
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