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UNICORN 7.0.1 Information Letter

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1. and overwrites the global phase Ref nbr 34584 Multiple Hold until instructions on the same breakpoint in a method does not work as expect ed Ref nbr 40869 UNICORN 7 0 1 Information Letter 29159401 AA 10 5 System Control module 5 System Control module The following scenarios mainly concern functions in the UNICORN 7 0 1 System Control module Several methods using the same column are Verify that the column can be placed in a system queue If the column reaches used for enough runs before the notification limit of how many runs that can more method runs are added to be performed before a CIP must be run the the system queue method runs will still proceed until all methods in the queue are finished The system queue will in effect bypass the set maximum number of runs before CIP Ref nbr 22042 Column statistics for the current run may be lost No further action required when data is recovered after a temporary connec tion failure between the instrument server and the database Ref nbr 22264 e Repair the OPC Core Compo nents In Windows Control Panel click Programs and features right click the OPC Core Components item and then click Repair or e Update the instrument con figuration to version 2 0 or later KTA avant 150 or version 3 0 or later AKTA avant 25 Restore the default view On the View menu click Restore to De fault 11 For AKTA avant the pro
2. that re scan and start of next method are not synchronized so a strategy download during run causes the queue in the CU to get full and the communication is lost Ref nor 34895 No data update is shown on the screen in System Control This can happen when the network cable between the CU and the PC has been disconnect ed and the CU memory gets full The method run at the time will complete its run but the scouting runs and the queued methods that follow will be cancelled Ref nbr 34458 For CU 950 and CU 960 based systems it is not possible to trigger the system notifications set in the Maintenance Manager in System Control Ref nbr 35394 Parameter values for the quaternary valve are changed in the start protocol but the run log in cludes the original parameter values Ref nor 33608 UNICORN 7 0 1 Information Letter 29159401 AA 5 System Control module Scenario Action Disconnect from the system In System Control hide or unhide the Method Naviga tor pane Connect to the system Restore the default view On the View menu click Re store to Default Disconnect and reconnect the system Restore the default view On the View menu click Re store to Default Disconnect and reconnect the system 13 1 2 Disconnect and reconnect the system Type in the variables do not copy and paste Let the data completely upload from the CU 950 or CU 960 A progress bar is shown
3. the the changes in E mail Setup to old address take effect Ref nbr 37333 UNICORN 7 0 1 Information Letter 29159401 AA F 4 Method editor module 4 Method editor module The following scenarios mainly concern functions in the UNICORN 7 0 1 Method Editor Scenario Action Error message is shown when saving a user cre No further action required ated method phase to the phase library if the phase contains a column Ref nor 11498 When a method containing invalid instructions is No further action required open it is not possible to open the Print or Dura tion amp Variables dialog boxes Ref nor 11476 Importing an individual column may cause a No further action required change in the access scope of the associated column type for example a predefined or personal column type is changed to global Ref nor 23172 Importing a method block into a phase will cause No further action required the phase to be shown as text edited However if the imported block also causes consequential changes in subsequent phases the affected phases may not be shown as text edited Changes made in the phase properties for these phases may cause errors Ref nbr 23233 When using the option Inject allsample using air If the air sensor sensitivity is set sensor for more than one sample with inlets on to High the sample application an extra sample inlet valve sample injected after may still proceed Contact the the first i
4. A 7 16 GE and GE monogram are trademarks of General Electric Company AKTA AxiChrom and UNICORN are trademarks of General Electric Company or one of its subsidiaries Windows Microsoft and SQL Server are registered trademarks of Microsoft Umetrics AB Corporation MODDE is a trademark o All other third party trademarks are the property of their respective owner Any use of UNICORN is subject to GE Healthcare Standard Software End User e Sciences Software Products A copy of this Standard License Agreement for Li Software End User License Agreement is available on request UNICORN 7 2009 2015 General Electric Company lectric Company All rights reserved 2009 2015 General First published Oct 2015 All goods and services are sold subject to the terms and conditions of sale of ealthcare which supplies them A copy of these terms e on request Contact your local GE Healthcare repre rent information the company within GE H and conditions is availab sentative for the most cul GE Healthcare Europe GmbH Munzinger Strasse 5 D 79111 Freiburg Germany GE Healthcare UK Limited Amersham Place Little Chalfont Buckinghamshire HP7 9NA UK GE Healthcare Bio Sciences Corp 100 Results Way Marlborough MA 01752 USA GE Healthcare Dharmacon Inc 2650 Crescent Dr Lafayette CO 80026 USA HyClone Laboratories Inc 84321 USA 925 W 1800 S Logan UT GE Healthcare Japa
5. UNICORN 1 Information Letter K 4 1 Introduction 1 Introduction This Information letter contains descriptions of different scenarios that may occur when UNICORN 7 0 1 is used If applicable actions to avoid or correct problems resulting from the described scenarios are suggested The information is valid for UNICORN 7 0 1 software build 7 0 1 167 Operating systems UNICORN 7 0 1 Client and Instrument Server is verified on the following operating system e Windows 7 Professional with SP1 installed 32 bit and 64 bit SQL Server The UNICORN database is verified for SQL Server 2008 R2 32 bit and 64 bit running on Windows 7 Professional with SP1 installed 32 bit and 64 bit e SQL Server 2012 with SP1 installed 64 bit running on Windows Server 2012 e 501 Server 2014 64 bit running on Windows Server 2012 2 UNICORN 7 0 1 Information Letter 29159401 AA 2 General items 2 General items The following scenarios concern miscellaneous general functions in UNICORN 7 0 1 OPC Scenario Action Scouting on the Any column and or Column No further action required SameAsMain is not supported for OPC Ref nbr 33793 The data gets truncated when retrieving very large Narrow down the data selection quantities of data through OPC Historical Data Access For example when retrieving the global audit trail for a year Ref nbr 35213 On a Windows 7 64 bit installation the OPC Core Iti
6. cess picture in the Process Picture pane is not updated properly with live in formation Ref nbr 22956 Selecting to unhide or hide the run log in System Control may have unexpected effects For exam ple the run log may appear behind the process picture if it is first hidden and the user then selects to show the run log Ref nbr 23449 UNICORN 7 0 1 Information Letter 29159401 AA 5 System Control module Scenario Action e Try again e Use an external software tool to make a screen cap ture e Wait until the method has ended and then retry e Wait until the method has ended and open the created result file Perform copy to clipboard copy to metafile from the Evaluation mod ule Reboot the computer Connect the cable and restart the UNICORN instrument server then start the methods or method queue again Restart the instrument server to activate the system notifica tions Do not change the parameter values for the quaternary valve in the start protocol Update the method instead Copy to clipboard and Copy to metafile do not show curves when pasted into other applications and do not open at all in some viewers This may be caused by additional data samples arriving at the copy operation or by too much data in the copied chromatogram Ref nbr 24932 An instrument module is lost and found during a scouting run and Preparing for new run is stated over and over again This is due to
7. during the upload The System Control panes are minimized and fixed in the upper left corner Ref nbr 35568 The System Control panes do not open after re connecting to an instrument that has been in power save mode Ref nbr 37743 It is not possible to perform manual instructions after reconnecting to an instrument that has been in power save mode and a method run has been started Ref nbr 37743 The instrument connection progress bar is never ending and cannot be canceled Ref nbr 35594 Variable values are pasted into the Start Protocol but when the method starts the old variable val ues are used Ref nbr 38004 The Windows user has been logged out or the computer has been shut down during a manual or a method run When the computer has restarted and the user has logged on to Windows the controls in System Control are grayed out during the data upload from CU 950 or CU 960 Note Data upload is only possible if it is an Ethernet connection between the computer and the CU and if the CU has a flash memory installed UNICORN 7 0 1 Information Letter 29159401 AA 5 System Control module Scenario Action Not possible to reconnect to the system in a net Set up the network to use a fixed work installation if the instrument controlling IP address for the rocker computer or in the case of cell cultivation the rocker loses network connection for a longer pe riod of time The
8. ftware can lock files that UNICORN needs to write to External software can affect the UNICORN soft As a first step of troubleshoot ware ing remove or deactivate any external software installed on the computer UNICORN 7 0 1 Information Letter 29159401 AA 5 2 General items Scenario Action All users should be informed about this limitation when changing passwords When setting passwords in a dialog box it is not possible to set Log on password and Signature password to the same password For example in the Log on UNICORN dialog box when you access a newly installed system for the first time If you set the same password for both Log on password and Signature password a warning message is received and you need to change the passwords before you can continue However it is possible to change passwords in any UNICORN module and then also to set the same password for both Log on password and Signature password If you set the same pass word in this manner you will not receive a warning and you do not have to change passwords in or der to continue UNICORN 7 0 1 Information Letter 29159401 AA 3 Administration module 5 Administration module The following scenarios mainly concern functions in the UNICORN 7 0 1 Administration module Scenario Anew e mail address has been set in E mail Set Restart the instrument server for up but alarm notifications are still sent from
9. n Corporation Sanken Bldg 3 25 1 Hyakunincho Shinjuku ku Tokyo 169 0073 Japan 29159401 AA 10 2015 a201 For local office contact information visit www gelifesciences com contact GE Healthcare Bio Sciences AB Bj rkgatan 30 751 84 Uppsala Sweden www gelifesciences com unicorn
10. njection will not be applied to the column GE Healthcare support for infor This is because air may be introduced between mation the first and the second sample inlet valves Ref nor 26205 8 UNICORN 7 0 1 Information Letter 29159401 AA 4 Method editor module Scenario Action A method that is imported from one system type to be used with another system must be convert ed If a method is imported and not converted the conversion of method parameters must be done manually A method that is imported from one system type to be used with another system must be convert ed The conversion of method pa rameters must be done manual ly The Adapt method function is not supported between KTA pure 25 and KTA pure 150 sys tems and vice versa For more information refer to KTA pure User Manual The column list must be import ed with the Column Type tab selected It is not possible when the Column tab is selected Click Confirm and Continue when the wizard states that you should click Continue Install the column list supplied on the DVD or download the latest version of the column list from the web updated regular ly When importing a method created for KTA avant 25 to an KTA avant 150 system the method will be saved for the larger system but the system related parameters will not be adjust ed Ref nbr 30147 Ref nbr 30307 When importing a method created fo
11. ogram where the properties of the x axis have been adjusted to 0 at injection the copied curve will not align correctly since the injection mark for the copied curve is not included Ref nbr 23914 When importing UNICORN 5 results larger than 10 MB an files could not be imported error is displayed Ref nbr 36448 When trying to export a result that contains curves the menu item Curves on the To Unicorn menu and the Externally menu under the File and Export menus are unavailable even though it should be possible to click Curves Ref nbr 37631 Some instructions in the Evaluation Procedure Editor are not correctly implemented and will not produce any output This applies to some of the export formats and some chromatogram operations UNICORN 7 0 1 Information Letter 29159401 AA 7 Evaluation module Evaluation module The following scenarios mainly concern functions in the UNICORN 7 0 1 Evaluation module Scenario Action Split the result into smaller re sults and import the subset re sults Then merge them in UNICORN 7 0 1 No further action required When importing UNICORN 5 results larger than 10 MB an files could not be imported error is displayed Ref nbr 36448 When importing UNICORN 5 x results where Any column has been used the column volume will not be stored correctly As a result the function Compare in CV does not work UNICORN 7 0 1 Information Letter 29159401 A
12. r KTA pure 25 to an KTA pure 150 system the method will be saved for the larger system but the system re lated parameters will not be adjusted Importing a new column list does not work An error message is displayed stating that the file is corrupt Messages during AxiChrom packing with Master are incorrect They tell you to click Continue after a specified action but the button is named Con firm and Continue The buttons are named differently in UNICORN 7 0 1 than in UNICORN 5 and since the wizard has not been changed between the two versions the information is invalid Ref nbr 35815 The column list installed in the UNICORN database is outdated Ref nbr 36473 UNICORN 7 0 1 Information Letter 29159401 AA Scenario Action The imported method must be saved before the signatures can be seen The same instrument configura tion as from where the method was exported must be installed in the target database prior to method import Avoid creating a personal phase with the same name as a global phase Separate each Hold until instruc tion by at least the minimum time resolution 0 01 hours 4 Method editor module Signatures are not visible in an imported method created with a system using a different instrument configuration than the connected system Ref nbr 37649 A user without access to create or edit global phases saves a personal phase with the same name as a global phase
13. rocker has been given a new IP address when reconnecting to the network Ref nor 40657 For KTA avant systems there is indications in the No further action required Run Log and the Audit Trail that user OPC is connected in view mode Since the Process Picture for AKTA avant uses OPC for receiving information from the system this does not indicate an error in the system 14 UNICORN 7 0 1 Information Letter 29159401 AA 6 Evaluation Classic module 6 Evaluation Classic module The following scenarios mainly concern functions in the UNICORN 7 0 1 Evaluation Classic module Scenario Action The instrument service has no access to the desktop of the logged in users so the user inter face of the application started by the RUN_PROGRAM instruc tion will not be displayed even if it is started by the instruction Instead of copying use the Open Curve function to open a copy of the curve including the injection mark curve Note that the result containing the curve must be saved before the curve can be opened Split the result into smaller re sults and import the subset re sults Then merge them in UNICORN 7 0 1 Close and reopen the result No further action required 15 The RUN_PROGRANM instruction does not open and display an image editing application as ex pected when itis used in an evaluation procedure at the end of a method run Ref nbr 14071 When copying a curve to a chromat
14. rver and all client computers in the network Buttons and other interface items are not posi tioned correctly in the UNICORN dialog boxes The system may behave unexpectedly if the client computer s clock is not in sync with the clock of the database server Ref nbr 23899 UNICORN 7 0 1 Information Letter 29159401 AA 2 General items Scenario Action Printing system performance reports from evalu There are two possible solutions ation procedures does not work Make s re thatthe Printto Ref nbr 29755 file check box is selected Ref nbr 29748 when starting a system per Ref nbr 28474 formance run this is the de fault option This will save a local copy in the UNICORN Temp folder on the UNICORN instrument server computer e Make sure that the UNICORN instrument server process is run by a Windows user with administration properties and defined printers instead of by the default local system ac count This will make the system performance and evaluation procedure to print as expect ed An anti virus and malware program detects a Allow the file to run as it is threat from the file opcenum exe Ref nbr 32798 The UNICORN performance is not optimal Shut down and restart UNICORN at regular intervals to ensure optimal performance Files that UNICORN needs to write to are locked Avoid virus scanning the because of a virus scan in the UNICORN folder UNICORN folder since some scanning so
15. s possible to verify that ver Redistributable is wrongly named as being version sion 105 1 is installed by check 105 0 The correct and installed version number ing the Version column for OPC is 105 1 Core Redistributable in the Pro grams and Features item in Control Panel The correct ver sion is listed as 3 00 10501 An internal error is displayed when a user that Restart the OPC Historical Data belongs to a different user group than the previ Access service ously logged in user tries to log in Ref nbr 298995 UNICORN 7 0 1 Information Letter 29159401 AA 3 Action Scenario 2 General items Upgrade If another UNICORN database is in use you must perform a manual database upgrade Re fer to a GE representative for in structions on how to do this Action When upgrading the database from the installa tion program only the database on localhost UNICORN named UNICORN will be up graded Note This scenario only applies if you are using an exter nal SQL server Scenario Other The size of Windows interface text must be set 100 in Win dows Control Panel 1 Click the Windows Start button 2 Type Display in the Start menu search field 3 Click the Display item that is displayed as the search result 4 Click 100 to set the size of text and other items on your screen 5 Click Apply Ensure that the computer clocks are synchronized between the database se

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