Home

Service Manual (Draft Version) Clinical Chemistry Analyzer

1. CHEMIX 800 SERVICE MANUAL 12 44 SERVICE TECHNICIAN QUARTERLY MAINTENANCE LOG Name of the Customer Name of the service technician Month From to Model CHEMIX 800 Serial No Quarterly Maintenance First Quarter Second Quarter Third Quarter Fourth Quarter clean the waste can clean the bio hazardous waste can clean and fill the deionised water can clean the cleaning solution can clean the level sensing platform check the levels of cal A solution replace if required clean the analyser external surface clean the computer trolley monitor keyboard and printer external surface maintain proper room cleanliness clean the area around the analyse and discard any unwanted items clean sample reagent 1 amp 2 probes clean the stirrer paddles clean the laundry probes clean the sample transport clean the reagent transport Clean check and if necessary the sample reagent 1 amp 2 syringe plunger tip clean the analyser fans clean the bar code reader replace the lamp Perform an auto span check Perform cuvette rinse check amp note cuvette blanks Perform a precision check Take a back up of all necessary data Patient results Parameters Calibration
2. 0 1 10111 92722 3215 OC OMY 326 lald ISNI ve 3sn4 27 asna m 54015 In ASSV 3Wv3 994 Ir 12468 SISSVHO ONILSVI 41915 339305 IZIS FL 3HIM HOVI SOOSSY3 ON EMS HOLIMS LNOU3 340 NO 1 31V 1d 4S088MO ON VE ASL SANS 9 0F 3215 FL OMY ON N 4535 19 OL 1215 8L UMP PPS d ah Is z OPOSSMO ON OG EFOSSMO ON m VEIL 3215 BB a 3218 II Fr DANY 3HIM HOV3 70 2995 90 6955 SON WWDZ 3A3318 N m F IZIS 18 MOTTIA IMS HOLIMS 3015 NANI SNIVI NOMI 1ROSSMO ON PL Hoya AN W9 A0EZ 14 ZH 09 06 OVAOSZISZI NOLLYINSNI 370v 143038 LOSNNOOSIC HOIND asna 11920606 LSV toL ELECTRICAL DESCRIPTION L as r ree PEOSSOM BOd IY 1
3. Ref CMX VER 05 05 05 Byte 1 Byte2 Byte3 Byte 4 Byte 4 Noise or Noise for Drift in Out of Out of Air for Air for Cal A Range for Range Sample CalA Sample and or Na Cal B Cal B and Error for Urine Urine Only Serum Plasma Urine 0 0 0 0 Error Noise Na 1 1 1 1 Drift or K 2 2 2 2 Out Na K 3 3 3 3 Of 4 4 4 4 Range Na Cl 5 5 5 5 CI 6 6 6 6 Na K Cl 7 7 7 7 Air S A B 2 i A Urine Only Byte 1 Byte 2 Byte 3 Byte 4 Byte 4 No 0 0 0 0 Na urine Error error only no out of range error Na 1 1 1 1 L Noise K 2 2 2 2 M Na Urine Driftor Na K 3 3 3 3 N Error Out 4 4 4 4 And Of 5 5 5 5 Out of Range Cl 6 6 6 6 7 7 7 7 Error 14 8 ISE MODULE 14 7 REAGENT CONSUMPTION Reagents Used The sample is aspirated from a sample cup and dispensed into the sample port at the top of the ISE module by the analyzer The sample is then positioned in front of the sensors using the double detector and the Waste Pump See Figure C 4 reagents are needed to operate the ISE module 1 Calibrant A 2 Calibrant B 3 Cleaning Solution 4 Urine Diluent Ref CMX VER 05 05 05 Used as wash solution and single point calibrator Calibrant A is pumped into the sample port by the Calibrant A pump and then positioned in front of the sensors A volume of 200ul is sufficient per
4. ASSY SNIHIM gOd YILVIH LOY 411 STVOICAN 0IE VISVSNVHI 2000 8209 ASSY LOU SANS 9 OL END LOU 7 oso s x z V 1 LI or thas 25514 YSNVY 9108 NNOO LOM Sr 3sva ELECTRICAL DESCRIPTION ON Oud 3WOS 50 04 52 008 XIIN3HO 0 9351 ASSY 0140 145 8 4 21000 STVOIGHN OId SIANNN 3009 ASSY 18V9 L2088MO HO DNILNOA HILAVI HOLIINNOI 9 SFAM dS LLOSSMO 9 1 WIN 3A33 1S XNIHHS 1 39108 9 HOLO3NNOO ZY gi ania COA NNOO IVNOIS 82d H S STI 393H 9108 wo 4 NS ASSV 04 140 504 8 oo 2 9 Y30710S 4 6 INO ZNS 2 0140 3WOH n ASSV 04 140 SOd 330108 4 21086 INO LNS ASSV 82d 0190 804 8 211 5 7 2 CHEMIX 800 SERVICE MANUAL m m sus vos TT 2
5. 65 54 0 soo zas zs 92475 E Di 5 1 CHEMIX 800 SERVICE MANUAL 008 XINIHO NO 5 ASSY 99 UOLVIOSI ZEZSUIX TILL 00 GIT SIVOITHWN OIH VISYVSNVAL 3000 E m 2 m Od ZEZSU Ch ASSV 82d YOLVIOSI 22288 04 080 05 13 z00SSQM ON ASSV MOTISA ONIGNIM A8 0 8 LXL 1 1 9 6 ELECTRICAL DESCRIPTION sun 0w ava ________ _______ ol 1 awos ASSY 99 YOLVINDIY 220004 INBAOM STVOITHA OIH VISVSNVHI 9 UISUSNUHI 8 0 5 LXL 8 055 2 Q OF NI2U 1 Sal 894 WOlVIno3H 820 3548 OL Q 8301971934 ASSY 04 YOLVINOAY 834 18 28513 U ISUSNUHI 12 NIn Idi IL 200888 ON 0 1825573 ASSV N CHEMIX 800 SERVICE MANUAL ciossam on PT T on sud
6. END POINT TEST FIXED TIME TEST KINETIC TEST GLU CHO CRE BUN GOT GPT GLU CHO CRE BUN GOT GPT GLU CHO CRE BUN GOT GPT GLU CHO CRE BUN GOT GPT GLU CHO CRE BUN GOT GPT GLU CHO CRE BUN GOT GPT GLU CHO CRE BUN GOT GPT GLU CHO BUN GOT GPT GLU CHO CRE BUN GOT GPT GLU CHO CRE BUN GOT GPT GLU CHO CRE BUN GOT GPT GLU CHO CRE BUN GOT GPT GLU CHO CRE BUN GOT GPT GLU CHO CRE BUN GOT GPT GLU CHO CRE BUN GOT GPT GLU CHO BUN GOT GPT GLU CHO CRE BUN GOT GPT GLU CHO CRE BUN GOT GPT GLU CHO CRE BUN GOT GPT GLU CHO CRE BUN GOT GPT MEAN MEAN MEAN SD SD SD CV CV CV NOTE CV should not Exceed 3 Ref CMX VER 05 05 05 Page No 5 48 RELOCATION 6 Relocation This section provides instructions for decontaminating draining out the analyser disconnecting peripherial devices and packing the analyser securely for transportation and is intended for use by only a Transasia Bio medicals trained Field Service Engineer 6 1 TOOLS AND MATERIALS REQUIRED FOR PACKING THE ANALYSER 6 2 UNINSTALLING AND DECONTAMINATING THE SYSTEM 6 3 PACKING THE ANALYSER 6 4 CERTIFICATE OF DECONTAMINATION Only a trained service representative should carry out the relocation of the NorE M analyzer Problems resulting from the r
7. ENId 1 ASSY 99d H3LV3H LOY LFI0IA ZNId 3fY18 15 MOTIAA Q3 NOLLO3NNOO 401 NMOUS LSS 2 2 CHEMIX 800 SERVICE MANUAL 90884 ON awos sorse ASSV 0140 dSV 8 10898 21000 1 SIVOIQGHW OIH VISYSNVAL 3009 26066 3 18VO Oldo 5 ASSV 82d 140 504 3339 MO TIJA 0140 4015 ASSV 99 OLdO SOd 87A907HINS LSM NNOO ELECTRICAL DESCRIPTION giossam 008 0 0351 SNOILO3NNOO NOLLO3S 1984 1000 SIVOIGHN OIH VISVSNVAL 3009 260845 SON c X uc SA33 S XNIHHS LV3H WINS H3 OS ONILSVO NO HLIM 38IM MOTISA OLOSSOM ON LINN H3TIOHLINOO 19M 3215 BL AG Q IDOHS SHIM ILON MOVIE 00SSGM SANS V8L AZL OL L9088MO ON 01085 H3TIOHLNOO YIOSSMI ON OL LOOSSAM 193 OL HOLIMS SNIVW NOHI
8. cx MEANnA SIVOIIER OIH CHEMIX 800 SERVICE MANUAL sin ram ASSY ONIUIM SANS 220004 VanNnN VISVSNVUL M38WnN 3009 Lond 198 ZEOSSMO ol gt IZIS 8 LINN HITIOHINO9 dNFL LOY NOVA 19085 DUCA vel Lv IZIS 8 SMV JHM LEOSSMO ON DAA TIAMNVaN V8T cI SANS 21 090 5 ASSV SYHLLTAd 194 100 ISSN ASSV NVA INIIA __ 9 5 1 7 1 e ELECTRICAL DESCRIPTION M son en fee cesses was wwf 008 x nano ms TI ASSY SANS V S 9 AvZ ZL000r Ivannn STVOIGHN OId VISVSNVAL YIANNN 3009 SEOSSMOJEL THNVIANOVE OL AND 0SSMO ON SISSVHO 96 09 3215 PL N TIHAANVHIN Sans VS9 96 66 IZIS 07 FUIM D I Nia al N 96 62 3216 02 DMV 4 1 X ZSOSSMI ON 2 ON Duda CHEMIX 800 SERVICE MANUAL 1 sossam to ded 11 SNOILO3NNOO SANS V Z A8F ALT ST
9. 4 3 2 Swivel Elbow 1 8 BSPT for tube OD 5 16 1 00 000358 4 4 CKD VALVE 24V DC SERIAL 4114 1 00RMEVA000001NIAN 4 5 CKD VALVE 24V DC SERIAL 4114 1 00RMEVA000001NIAN 4 6 CKD VALVE 24V DC SERIAL 4114 1 00RMEVA000001NIAN 4 7 CKD VALVE TYPE 21 01 03A 100V 1 00RMEVAO000002NIBN 4 7 1 Thread To Barb Adapter Fittings 1 8 Bspt 1 8 L2 1 00RMEBTO000368PICN 4 7 2 Thread To Barb Adapter Fittings 1 8 Bspt 1 8 L2 1 00RMEBTO000368PICN 4 8 CKD VALVE TYPE 21 01 03A 100V 1 00RMEVA000002NIBN 4 8 1 Thread To Barb Adapter Fittings 1 8 Bspt 1 8 L2 1 00RMEBTO000368PICN 4 8 2 Thread To Barb Adapter Fittings 1 8 Bspt 1 8 L2 1 00RMEBTO000368PICN 4 9 CKD VALVE TYPE 21 01 03A 100V 1 00RMEVA000002NIBN 4 9 1 Thread To Barb Adapter Fittings 1 8 Bspt 1 8 L2 1 00RMEBT000368PICN 4 9 2 IThread To Barb Adapter Fittings 1 8 Bspt 1 8 L2 OOIRMEBTO00368PICN 5 0 END USE 5 0 1 Y Connector with 200 Series Barbs 1 16 1 5 mm ID Tubing 00RMEGI000146NIBN 5 0 2 Y Connector with 200 Series Barbs 1 16 1 5 mm ID Tubing 00RMEGI000146NIBN 5 0 3 Y Connector with 200 Series Barbs 1 16 1 5 mm ID Tubing 00RMEGI000146NIBN 5 0 4 Y Connector with 200 Series Barbs 1 16 1 5 mm ID Tubing 00RMEGI000146NIBN 5 0 5 Y Connector with 200 Series Barbs 1 16 1 5 mm ID Tubing 00RMEGI000146NIBN 5 0 6 Y Connector with 200 Series Barbs 1 16 1 5 mm ID Tubing 00RMEGI000146NIBN
10. With the help of a or syringe pipette 300 to 500 ul of tap water As tap water has ions for conduction Do not use deionised or distilled water into cuvette number 50 and 42 51 8 the sample tray 1 Select SERVICE CHECK SAMPLE ARM INITIALISE Sample probe mean distance between the gt TROUGH TO SAMPLE OUTER gt SAMPLE TO dispense needle and sensor needle to be at CUVETTE gt DOWN gt the centre of the respective cuvette The Sample probes moves down until it senses the present of liquid in the cuvette and then stops NOTE Take care that the centring is not Verify that the hollow dispense needle is in the disturbed while tightening the Allen screw centre of the cuvette 2 Adjust the sample probe as follows Lift and remove the probe plastic cover and locate the Allen Screw on the top end of the arm shaft Slightly loosen this Allen screw and rotate the top plate of the arm so as to position the mean distance between the dispense needle and sensor needle to be in the centre of the cuvette When doing this make sure that only the horizontal top plate rotates and the main vertical shaft is stationary Tighten the Allen screw Verify proper centring by repeating steps 1 to 2 Select INITIALISE SAMPLE OUTTER gt DOWN Verify that the dispense needle is at the The Sample probes moves down until it senses the present of centre of the sample Outer number1 liquid in cup number 1 and then stops Select
11. 11 gt 2 1 4 12 PH HD SCREW Y Y PW NW 4 NOS COVER FOR TRANSDUCER FSPS1451 1 1 M3x8 PH HD SCREW 7 PW NYLON 2 NOS Y COVERFOR g 1 TRANSDUCER FSPS5013 x Y Y Y Y c GASKET FOR TRANSDUCER COVER FSPS5012 S mn en REFER DRG XLAD 211 LOAD CELL PLATFORM ASSEMBLY CHEMIX 800 SERVICE MANUAL 10 Hydraulic Description This section explains the hydraulic connection diagram and the cuvette rinsing unit 10 1 HYDRAULIC SYSTEM OPERATION 10 2 HYDRAULICS DIAGRAM 10 3 CUVETTE RINSING UNIT Hydraulics Description Hydraulics Description CHEMIX 800 SERVICE MANUAL 10 1 HYDRAULIC SYSTEM OPERATION The hydraulic system consists of the valves pumps tubings pressure vessel and the laundry system mentioned below are the functions of the various valves and pumps Valve and Pump Functions WATER CKD VALVE Enables Disables the flow of deinosed water from from the pressure vessel to the laundry probes STIR CKD VALVE Enables Disables the flow of deinosed water from from the pressure vessel to the Stirrer troughs R2PT SPT CKD VALVE Enables Disables the flow of deinosed water from from the pressure vessel to the Reagent 2 arm and Sample arm trough R1PT CKD VALVE Enables Disables the flow of deinosed water from from the pressure vessel to the Reagent 1 ar
12. etc Mobile phones should not be operated close to the Analyser Ref CMX VER 05 05 05 Page No 4 4 PREINSTALLATION VERIFYING PROPER ROOM LIGHTING There should be sufficent room lighting the lighting should be even and there should be no shadow areas this problem can be eliminated by the use of multiple light source from diagonally opposite directions This will enable efficent operator use and will give a clear visable access to the internal components of the analyser during operation and technical serviceing 4 4 FLOOR REQUIREMENTS Me SASA 7 LOAD CELL 27 22 7 BLATTORM 22 27 2 2 222 272 Y gg 4 7 Gf 2 27222 27 COMPUTER PRINTER 222224442 CHEMIX 800 SCH a 277 ANALYZER 27 7 729 JA D 221 22 YH 7 MG 20222 1990 610 508 2 ALL DIMENSIONS ARE IN mm TOTAL FLOOR REQUIREMENTS Ref CMX VER 05 05 05 Page No 4 5 Preinstallation CHEMIX 800 SERVICE MANUAL 4 5 CHEMIX 800 WOODEN CARTOON DIMENSIONS amp WEIGHTS WOODEN CARTOON DIMENSIONS amp WEIGHT LENGTH 120 to 130 CENTIMETERS WIDTH 80to 90 CENTIMETERS HEIGHT 130 CENTIMETERS NETT WEIGHT 165 00 Kilos GROSS WEIGHT 195 00 Kilos Ref CMX VER 05 05 05 Page No 4 6 INSTALLATION 5 In
13. 022220 ASSY 32018 1 AS 9 91 call 22000 WANNAN II STVOIGHN OId VISVSNVelL YIENNN 3002 ON v 9 08SMD ON anoLe MOVIE PLS ano 22728 eco SIVE 9 114 AVC 13101A BKPL2 5 24V NNOO HIMOd 2 9 1 AZIS NL 96 62 4215 06 AS en ozr LOSVOS asva 6OSSMO ON DUC 425 22 QN9 AS 95 52 3215 02 SMV 194 LHIOIA 890SSMO ON 1310lA IN AS 9 Abe 96 62 3715 02 Er 1111 i ceri pi el 2101919191912161919 0 0 91919191016191091 9 0 83 asawa nosaasn 1111 LI TITCITITLITT AS AS COND Ave Ave 5 5 MEW 881 42018 IWNINYAL ELECTRICAL DESCRIPTION 9 085 SIN NNOO 9 ASSV ONIYAITS 104 ALT SIVOIGHW OIS VISVSNVeLL M38WnN 3009 V I 2 er 1 80 6999 80 2999 X310W NNOO 98 NNOO ru r umoozz AWAD ania MOTIBA TEL I SONVEO er 7 t Jo 8 L 9 1 ASSY 104 NAOSS ps 31IHM
14. CHEMIX 800 SERVICE MANUAL 6 08601 RIE swos ses mew wo 008 XIIN3HO 0350 Lb ASSY 140 WHY 291418 210009 1 8 11111111 STIVOIAAN OIA VISVSNVAL M38WnN 3009 oo dH 43d 10s 4 IND ENS OLdO ASSV 90 0180 SOd IHIH H3Qq 10s 4 ZNS OldO ASSV 82d OLdO 504 5 4 LNS 0140 ASSV 82d 01401 50 21085 NOLO3NNOO N Nid 9L CON ELECTRICAL DESCRIPTION OZOSSOM addy ON xwos 008 XIA3HO 0350 OLdO 5 445 9 STVOIGHN OId VISVSNVAL 3009 5 ddS 59066 2 ON 39NIHAS 5 ddl AN HO 5 1 2 ASSV 99 0140 504 MOTISA JONVHO ASSV 99 0140 1804 MOVIA 40105 NMOUI 2 CHEMIX 800 SERVICE MANUAL 210007 STVOIGHN OId VISVSNV LL SIANNN 3009 NIIHO i CNS 1 99085 940 ASSV 140 1 INS LANNO ASSV 99 0140 15
15. not shown to indicate the pressure developed inside the pressure tank Pressure transmitter Pressure sensor to monitor the pressure inside the pressure tank Heater Resistance heater meant for heating the DI water inside the pressure tank Thermostat To control the power supplied to the heater Thermal cutoff switch Safety switch meant for cutting off the power supply in case of over heating may in the case of thermostat failure PRESSURE TANK VESSEL NOTE APPLY HEAT SINK COMPOUND ON THE SURFACE OF THE THERMOSTAT amp HEATER BEFORE INSERTING IT INTO PRESSURE VESSEL PRESSURE 2 TRANSDUCER TOP COVER PLATE OF M3x12 PH HD SCREW PRESSURE TANK 5 6 N USE O RINGID 85 CY THK 5 MATL NITRILE REFER FSPS2370 gt m 27 PRESSURE TANK FSPS2370 PRESSURE TANK VESSEL ASSEMBLY Thermal Cut off Switch BN M3x6 GRUB SCREW BLACK 3 THERMOSTAT 2 NOS HEATER A 9 8 LEVEL SENSING PLATFORM ASSEMBLY D Function The Bio hazardous waste and Wastes generated in the machine are directed and collected in 10lt and 201 cans respectively And the inputs to the system i e DI water and Cleaning solution are supplied to the instrument through 201 cans and 101 can respectively To help monitoring whether the cans are filled up and need replacement in case of waste containing cans or emptied and need replacement in case of DI water and Cleaning solution
16. yt er RCTHET WGI 128 sr 3003888 858 10 00 11330801 a ear I HOLIMS 83002 198 3402898 194 44908 3598 18780024513 UISUSNUHI CO WHOD 198 220128 HOLIMS LOU O ONG ASSV O313 N ELOSSVA ASSV 2414 910653 ASSV 9373 NOLLVOINPININOO 26254 22254 35101 LINN U3TIOULNOD ANSL 193 YANNVOS 000 HJNNVOS 900 g R CHEMIX 800 SERVICE MANUAL ZL000r 1vannn GIT STVOIGHN OId VISVSNVAL 3009 uv NO ans PZOSSMI 202 21 81 IND zuus d INVIA MOVE ser ver 0557 128 5 5 1 m Gol er ser Ter ar Ga gr 8 103 3 5 5 5 a lt lec 2 2 WS IND 5 5 ws 8 8 es HE pes 2 n e 15 7 j d 2 2 a oe 9 9 1 5 1 4 8 ser ver gar zer ozr ruin 129 a a si T si E bi a 305 18301 RU MTR CWS5011 2 MAS 211 na GLOSSMO
17. CLEAN THE ANALYSER INTERNAL SURFACE FREE OF DUST 23 PERFORM AN AUTO SPAN CHECK AND NOTE DOWN THE GAIN VALUES FOR 340 WAVELENGTH 24 PERFORM A CUVETTE RINSE 25 PERFORM A PRECISSION CHECK AND NOTE DOWN THE FOR AN END POINT AND KINETIC TEST 26 CARRY OUT A SITE VERIFICATION FOR TEMPERATURE LINE VOLTAGE ELECTRICAL GROUND VENTILATION EXTERNAL INTERFERENCES ROOM LIGHTING AND LABORATORY CLEANLINESS PRACTICE AS DESCRIBED IN CHAPTER 16 1 SERVICING A CUSTOMER SITE 27 MAKE A DETAILED ENTRY IN THE ERROR LOG BOCK OF THE MAINTENANCE CARRIED Ref CMX VER 05 05 05 Page 12 8 PREVENTIVE MAINTENANCE OUT AND AND SITE VERIFICATIONS Ref CMX VER 05 05 05 Page No 12 9 CHEMIX 800 SERVICE MANUAL ANNUAL MAINTENANCE 1 CLEAN THE WASTE CAN CLEAN THE BIO HAZARDOUS WASTE CAN CLEAN AND FILL THE DEIONISED WATER CAN Bi CLEAN THE CLEANING SOLUTION CAN CLEAN THE LEVEL SENSING PLATFORM REPLACE EXTERNAL TUBINGS TO THE WASTE BIO HAZARDOUS WASTE CLEANING SOLUTION AND DEIONISED WATER CANS CHECK THE LEVELS OF CAL A SOLUTION REPLACE IF REQUIRED CLEAN THE ANALYSER EXTERNAL SURFACE CLEAN THE COMPUTER TROLLEY MONITOR KEYBOARD AND PRINTER EXTERNAL SURFACE 10 CLEAN THE AREA AROUND THE ANALYSER DISARD ANY UNWANTED ITEM MAINTAIN PROPER ROOM CLEANLINESS 11 CHECK AND REPLACE IF NECESSARY THE SAMPLE R
18. MAINS INPUT amp POWER SUPPLY DISTRIBUTION TX1 TRANSFORMER ASSEMBLY 12V 18A SMPS WIRING ASSEMBLY 24 V 6 5A SMPS WIRING ASSEMBLY 48V 2A SMPS WIRING ASSEMBLY 36 V 2A SMPS WIRING ASSEMBLY 12 SMPS WIRING ASSEMBLY 15 V 3 4A SMPS WIRING ASSEMBLY 5 V 5A SMPS WIRING ASSEMBLY RGT TEMP CONTROLLER WIRING CONNECTION XLRS232 ISOLATOR PCB WIRING ASSEMBLY REGULATOR PCB WIRING ASSEMBLY RCT HEATER PCB WIRING ASSEMBLY R1 R2 amp SPT ARM OPTO ASSEMBLY TB3 24V amp 5V TERMINAL BLOCK WIRING ASSEMBLY RCT SLIPRING ASSEMBLY amp HEATER amp SENSOR CONNECTOR RGT RCT amp ASP OPTO WIRING ASSSEMBLY RGT COOLING SECTION WIRING CONNECTIONS STIR1 amp 2 ARM OPTO ASSEMBLY SPP R1PP amp R2PP SYRINGE OPTO WIRING ASSEMBLY CRU SN1 amp SN2 WIRING ASSEMBLY RCT HEATER WIRING ASSEMBLY ELS52015 RO BASE BOARD 1 PCB WIRING ASSEMBLY ELS52008 R1 BASE BOARD 2 PCB WIRING ASSEMBLY ELS52005 R1 BACKPLANE 1 PCB WIRING ASSEMBLY ELS32010 R1 BACKPLANE 2 PCB WIRING ASSEMBLY REAR PANEL LOADCELL CONN ASSEMBLY amp WASTE MOUNTING BRACKET LED WIRING ELS52002 R2 INTERFACE PCB WIRING ASSEMBLY RCT SENSORS AD590 WIRING ASSEMBLY DIAGRAM SPT R1PT amp R2PT ASSEMBLY WIRING ASSEMBLY DAIGRAM SYRINGE SPP R1PP amp R2PP WIRING AND LOOPING DIAGRAM STIRRER 1 8 2 WIRING amp LOOPING DIAGRAM CRU ASSEMBLY WIRING AND LOOPING DIAGRAM ELS32003 RO AC DRIVE PCB WIRING ASSEMVLY Electrical description CHEMIX 800 SERVICE MANUAL WARNING CAUTION Voltages pre
19. Reagent 2 arm 1 2 3 4 5 6 Initialization This command will bring R2 arm at home position trough position Up If R2 arm is down at trough position or in reagent tray this command will bring R1 arm at up home position till the up opto doesn t cut Down this command can be used to check down movement of R2 arm First give lt initialize gt command then give lt To reagent inner To Reagent outer command 4 then give Down command The R2 arm will go down until the bottom of the reagent bottle While going down if it senses liquid level in between it will stop at that level If liquid is not there in reagent bottle then it will go down will experience VOD at bottom and displays 45 R2 arm VOD error Link This command is used to set R2 Arm Motion Cycle continuously for validation and service check test To execute initialized the arm first by clicking initialized button after complete initialization force link command by clicking link button once To terminate action use stop button provided on the left hand side corner of the screen RCT Home For R2 arm alignment RCT should be at Home initialization position Align R2 inner This command will first initializes RGT tray amp align reagent position 1 for R2 arm calibration 7 Align R2 outer This command will first initializes RGT tray amp align reagent position 4 for R2 arm calibration 8 Default calibration This comm
20. Shutoff 1 00RMEBTO000347NICN 107 Change inline coupling body HOSE BARB with shut off for 1 00RMEBTO000353NICN 1 8 ID tubing 1 0 8 1 8 HB valved panel mount insert 1 00RMEBTO000340NICN 109 Quick Change inline coupling body HOSE BARB with shut off for 1 00RMEBT000353NICN 1 8 ID tubing 1 1 IDI WATER CAN 1 2 ASP 1 3 RGT 14 WASTE 1 5 BIO HAZARDOUS WASTE CAN 1 6 DETERGENT CAN 2 0 CONTROL ELEMENTS 1 2 1 SHUTOFF VALVE 1 00RMEOTOO0668NLAN 3 0 PRIME MOVERS 3 0 1 Tee Connector with Classic Series Barbs 5 32 4 mm ID Tubing 1 00 RMEGIO000111NIBN 3 0 2 Tee Connector with Classic Series Barbs 1 8 3 mm ID Tubing 1 00RMEBTO000360NICN 3 0 3 Tee Connector with Classic Series Barbs 1 8 3 mm ID Tubing 1 00RMEBTO000360NICN 3 1 PUMP 230 50Hz 6 BAR PRESSURE 1 00RELPUO00003NIAN 3 1 1 Swivel Elbow 1 8 BSPT for tube OD 5 16 1 00RMEBTO000358NICN 3 1 2 Swivel Elbow 1 8 BSPT for tube OD 5 16 1 00RMEBTO000358NICN 3 2 SPP SYRINGE 321 Thread with 5 16 Hex to 200 Series Barb 1 16 1 5 mm ID 1 00RMEGI000149NIBN 3 2 2 ETFE FERRULE 1 00RMEBT000350NICN 3 2 2 FERRULE NUT 1 00RMEBTO000351NICN 3 2 3 ETFE FERRULE 2 00RMEBTO000350NICN 3 2 3 FERRULE NUT 2 00RMEBTO000351NICN 3 2 3 LOW PRESSURE STANDARD UNION 1 00RMEBTO000352NICN 3 2 4 ETFE FERRULE 2 00RMEBTO000350NICN 3 2 4 FERRULE NUT 2 00RMEBTO00035
21. To rotate the RCT tray to the offset position SERVICE CHECK STIRRERS gt Click RCT OFFSET button 1 Select INITIALISE gt ROTATE TO CUVETTE 1 DOWN The Stirrer paddle No 1 goes into cuvette No 50 amp Stirrer 2 Verify that Stirrer 1 is at the centre of the goes into the spare hole on 5 piece top cuvette No 50 amp Stirrer 2 is at centre of Select spare hole on 5 piece top Stirrer Paddle shaft Cuvette wall 1 Select INITIALISE gt ROTATE TO CUVETTE 2 DOWN Verify that the stirrer 1 is at the centre of cuvette No 39 amp Stirrer2 is at the centre of cuvette No 50 Select the ON button to start the Stirrer paddle motors 2 Adjust the Stirrer paddles as follows Lift and remove the Stirrer arm plastic cover and locate the Allen screw on the top end of the arm shaft NOTE Make sure that the stirrer paddles do not touch the walls and the bottom of the Ref CMX VER 05 05 05 Page No 5 26 INSTALLATION Slightly loosen this Allen screw and rotate the top plate of the arm so as to position the paddle No 1 in the centre of cuvette no 39 and paddle No 2 in the centre of No 50 When doing this make sure that only the horizontal top plate rotates and the main vertical shaft is stationary Tighten the Allen screw 3 Verify proper centring by repeating steps 1 to 2 cuvette NOTE Take care that the centring is not disturbed while tightening the Allen screw Stirrer Paddle shaft Cuvette
22. the levels of all these cans are monitored indirectly through measuring the changes in weights of each of the cans by means of load cells associated with each can The level sensing platform can either be placed behind the machine or by the side of the machine To facilitate easy removal of the tubing quick couplings non drip type are provided at the rear of the instrument Component Function Operation Load cells 4 nos of loadcells meant for DI water Bio hazardous waste Normal Waste and Cleaning solution are provided respectively Waste Cans 20 It can is for waste and 10 It can is for biohazardous waste Cleaning solution can 10 It can meant for containing cleaning solution DI water can 20 It can meant for containing DI water Trays 4 nos of trays meant for receiving the cans of DI water Bio hazardous waste Normal Waste and Cleaning solution are provided MODEL XL 600 300 DESCRIPTION 10 LT CAN TRAY FSPS1454 2 NOS 20 LT CAN TRAY 47 FSPS1453 Y 7 1 Y 4 Un Y 1 B UE TRANSDUCER BOTTOM PLATE FSPS1456 4 NOS Y RUBBER SEAL FOR TRANSDUCER E FSPS2481 Load Cells Y TRANSDUCER COMPLETE ASSY 20LT CAN TRAY FSPS1453 10 LT CAN TRAY FSPS1454 2 NOS M6x20 CSK SCREW 16 NOS y FOR TRANSDUCER 11 i E Y Y Y
23. 9 6 REAGENTS TRANSPORT RGT ASSEMBLY A Function The Reagents Transport RGT Assembly consists of Base Assembly and the Tray Assembly The receptacles in the tray are designed to receive 30 nos of 20ml bottles and 30 nos of 70 ml bottles of Hitachi Design The positions of the bottles are alternately numbered w r t inner bottles and outer bottles The reagent bottles meant for R1 are of 70ml and are to be accommodated in the inner ring whereas the reagent bottles meant for R2 are of 20ml and are to be accommodated in the outer ring The RGT assembly is capable of identifying the barcode labels stuck onto the sample tubes by means of Reagent Barcode Reader The reagent tray assembly is provided with thermally insulated lid provided with an interlock by means of a proximity switch Components of ASP assembly Component Function Operation Reagent Tray Tray which receives the reagent bottles Rotation Motor Stepper Motor Imparts rotary motion to the reagent tray Home position sensor Opto interruptor For sensing the home position of the reagent tray Rotation position sensor Opto Interruptor Senses the rotational position of the Reagent Tray Barcode Reader Not shown in the figure Meant for identifying the reagents by means of barcode labels stuck on to the reagent bottles RGT container The container which houses the Reagent base assembly and the reagent tray RGT Cover Lid that covers RGT assembl
24. Description Functional Description CHEMIX 800 SERVICE MANUAL CHEMIX 800 TOP VIEW Ref VER 05 05 05 Page No 3 2 FUNCTIONAL DESCRIPTION 800 LEFI SIDE VIEW Ref CMX VER 05 05 05 Page No 3 3 Functional Description Functional Description CHEMIX 800 SERVICE MANUAL CHEMIX 800 RIGHT VIEW Ref VER 05 05 05 Page No 3 4 FUNCTIONAL DESCRIPTION CHEMIX 800 REAR VIEW Ref VER 05 05 05 Page No 3 5 FUNCTIONAL DESCRIPTION Hydraulics section of chemix 800 as viewed from R H S Ref VER 05 05 05 Page No 3 7 Functional Description Functional Description CHEMIX 800 SERVICE MANUAL Ref VER 05 05 05 Page No 3 8 FUNCTIONAL DESCRIPTION Top View with the Flap Open Sample Tray Reagent Tray Ref CMX VER 05 05 05 Page No 3 9 Functional CHEMIX 800 SERVICE MANUAL 3 2 SERVICE MENU SOFTWARE LAYOUT AND FUNCTION To Enter the Service Mode press Service Button on the Main Screen To quit the Service mode press the go back key on the menu Description Only Authorized Technical Service Personnel should operate the Service Menu 800 Service Check Sample SampleTray Reagent 1 Reagent Tray Reagent 2 Arm CRU amp Reaction Tray Stirrers Pump amp Trough Valve Reagent 1 arm 1 Initialization This comma
25. O 18 G00ZG5 13 VISVSNVAIL B TNO ddZu IND 1928 vir us ae Sk lt 15 8 IND Pola a 5 IND das iNOldS eT m EX a sr ICWS5027 SPP SYR _ 55010 BP MTR IBB1 R1 MTR BB1 R2 MTR SPT CWS5021 ARM SPT CWS5022 ARM CN2 TY W CWS5009 SEOSSMI BAS ELECTRICAL DESCRIPTION CHEMIX 800 SERVICE MANUAL LL __ CON 949 80000001 008 XINSHO 88 11 ONILNMOW EET ZL000b IVBAD 11111111 STVOIGHN OId VISVSNV4L 3009 1 ONLLNNON AA a OTTO RE ROS EP Men qu E eere em 3309 6 OMS 96 9 OMVIZ 318V2 1V 14 96 DMY 5 3309 6 1 NId9 90 886 Y 3 ERE OOLSSMO ON Tayovud N 71399907 aam NId9 90 6955 9E PLOMY Z zoossam ON NNOD 938 IXL OL ASSY HIONONVHIL OL LNOO 3 3dALG NId6 T1390v01u03 NOO 3dALQ A
26. The buzzer should turn OFF and the LED marked Waste should go OFF CKD VALVES VERIFICATION PROCEDURE ACTION OBSERVATIONS Locate and the pressure on the pressure gauge Pressure gauge should be between 0 8 and 0 9 bar Go to the Service check menu click on the pump Observe a small fountain of water in R1PT R2PT SPT amp and trough valves button Switch ON the CKD Stirrer troughs valves for R2PT SPT STIRR one after the other Switch ON all the switches together and keep the Verify that the water flow should be smooth and there hydraulic assembly ON for some time till the entire should be no leakages and that the pressure gauge does water line is primed and free of trapped air bubbles not fluctuate LAUNDRY FLOW ADJUSTMENT PROCEDURE ACTION OBSERVATIONS CLEANING SOLUTION FLOW ADJUSTMENT PROCEDURE Go to service check menu and initiate a cuvette Monitor the flow of cleaning solution from the rinse cycle cleaning solution can to the DET pump trough the tubing s to the first laundry probe and into the first cuvette To regulate the detergent flow remove the right side regulate the detergent flow remove the right side Ref CMX VER 05 05 05 Page No 5 30 INSTALLATION panel and locate the black coloured flow regulator on the top of the detergent pump Adjust it in order to enable the detergent flow into the first cuvette to fill up to of the total volume of the cuvette V
27. sample run Used as the second point in two point calibration Calibrant B is aspirated from a cup on the analyzer at least once a day or every 8 hours depending upon the laboratory schedule A volume of 500 uL is sufficient for one day s requirements This calibrant however should be placed on the host analyzer just before use to prevent a change in values from evaporation Should be run once a day to prevent protein buildup or at 8 hour intervals if the ISE Module performs greater than 50 samples per day Cleaning Solution may be aspirated from a sample cup 500 uL is sufficient for one day s requirements This is required for urine samples Urine samples must be diluted by a factor of 10 to perform urine measurement The host analyzer must thoroughly mix the diluent and sample before dispensing of the diluted sample into the ISE Module 14 9 ISE Module ISE Module CHEMIX 800 SERVICE MANUAL 14 8 Acceptable Calibration Ranges The following are the acceptable calibration values displayed at the bottom of the screen after completion of an ISE calibration Na Slope 50 to 63 mv Decade K Slope 50 to 63 mv Decade CI Slope 40 to 55 mv Decade Ref CMX VER 05 05 05 Page No 14 10 ISE MODULE 14 9 Troubleshooting Symptom Problem Correction System does not 1 RS232 cable is disconnected Reconnect or replace cable respond damaged 2 Module 5 has been Replace board amaged 3
28. 000341 542 bees ELBOW 3 8 NPT FOR 3 8 ID TUBING ELDON JAMES 1 00RMEBTO000363NICN 1 8 27 NPT Thread Elbow with 7 16 Hex to 200 Series Barb 1 4 5 4 3 6 25 mm ID Tubing 1 00 000341 1 8 27 Thread Elbow with 7 16 Hex to 200 Series Barb 1 4 5 4 4 6 25 mm ID Tubing 1 00 000341 1 8 27 Thread Elbow with 7 16 Hex to 200 Series Barb 1 4 5 4 5 6 25 mm ID Tubing 1 00 000341 1 8 27 Thread Elbow with 7 16 Hex to 200 Series Barb 1 4 5 4 6 6 25 mm ID Tubing 1 00 000341 1 8 27 Thread Elbow with 7 16 Hex to 200 Series Barb 1 4 5 4 7 6 25 mm ID Tubing 1 00 000341 1 8 27 Thread Elbow with 7 16 Hex to 200 Series Barb 1 4 5 4 8 6 25 mm ID Tubing 1 00 000341 5 5 CRU UNIT 5 5 1 CRU MANIFOLD 1 55414 ro Thread with 1 4 Hex to 200 Series Barb 1 16 1 5 mm ID 1 00 000135 A 5 5 1 2 QUICK CONNECTOR WITH SEALING RING 1 8 1 00 1000145 5513 EUH with 1 4 Hex to 200 Series Barb 1 16 1 5 mm ID 1 00RMEGIO00135NIBN 5 8 Thread with 1 4 Hex to 200 Series Barb 1 16 1 5 mm ID 5 5 1 4 Tubing 1 00RMEGIOO00135NIBN E515 with 1 4 Hex to 200 Series Barb 1 16 1 5 mm ID 1 00 000135 5 5 2 CRU MANIFOLD 1 5524 5 8 Thread with 1 4 Hex to 200 Series Barb 1 16 1
29. 1 Deterioration of sensing electrode Replace problem sensor and test ingle Electrod i Purge the Cal A and recalibrate the 2 May occur when new sensor or module If the sensor is new it new bottle of Cal A is installed on 22 i initially drift as it rehydrates over the system course of 15 minutes Drift Error Flag 1 Deterioration of reference electrode Replace reference electrode and retest Ref CMX VER 05 05 05 Page No 14 11 ISE Module ISE Module CHEMIX 800 SERVICE MANUAL environmental source Symptom Problem Correction Multiple a Check for electrical noise coincident Electrode 2 Electrical spikes from with activation b Component failure on module board Replace board 3 May occur when new sensor or new bottle of Cal A is installed on system Purge the Cal A and recalibrate the module Air in Sample 1 Insufficient sample pipetted into module sample port a Host instrument must deliver 70 ul Increase dispense volume b Operator must place sufficient sample in sample cup to account for all test programmed 2 Sample not positioned properly a Pump not connected properly b Pump tubing obstructed or tubing length is excessive Air in Sample and Cal A 1 Sample and Cal A are segmented with air 2 Fibrin or salt is plugging the sensor flow path 3 Bubble detector is malfunctioning a Sensors are not properly compressed
30. 1 00RMEBT000357NICN 4 0 CONTROL ELEMENTS 2 4 0 1 Tee Connector with Classic Series Barbs 5 32 4 mm ID Tubing 1 00 RMEGIO000111NIBN Straight Through Reduction Connector with Classic Series Barbs 5 32 4 4 0 10 imm and 1 16 1 5 mm ID Tubing 1 00RMEBTO000356NICN Straight Through Reduction Connector with 500 Series Barbs 1 8 3 4 0 11 mm and 1 16 1 5 mm 1D Tubing 1 00RMEBTO000355NICN Straight Through Reduction Connector with 500 Series Barbs 1 8 3 4 0 12 Imm and 1 16 1 5 mm ID Tubing 1 00RMEBTO000355NICN 4 0 13 Elbow Connector with Classic Series Barbs 1 8 3 mm ID Tubing 1 00RMEBTO000349NICN STRAIGHT THRU CONNECTOR WITH BARBS 3MM ID TUBING 4 0 16 PART NO N430 1 1 00RMEGIO000114NIBN 4 0 2 Tee Connector with Classic Series Barbs 5 32 4 mm ID Tubing 1 00 RMEGIO000111NIBN Straight Through Reduction Connector with Classic Series Barbs 5 32 4 4 0 3 Imm and 1 16 1 5 mm ID Tubing 1 00RMEBTO000356NICN Straight Through Reduction Connector with Classic Series Barbs 5 32 4 4 0 4 Imm and 1 16 1 5 mm ID Tubing 1 00RMEBTO000356NICN 4 0 5 Tee Connector with Classic Series Barbs 5 32 4 mm ID Tubing 1 00 RMEGIO000111NIBN 4 0 6 Tee Reduction Connector with 200 Series Barbs 1 16 1 5 mm and 1 8 1 00RMEBTO000361NICN 3 mm ID Tubing 407 Tee Reduction Connector with 200 Series Barbs 1 16 1 5 mm and 1 8 1 00RMEBT000361NICN 3 mm ID
31. 2 command amp Give Down command if RCT is rotating then don t give the down command Up If stirrer is down then it will go to up home position Rotate To cuvette 1 First give lt initialize gt command Then give lt Rotate To cuvette 1 stirrer will rotate to cuvette 1 of RCT Rotate To cuvette 2 First give lt initialize gt command Then give lt Rotate To cuvette 2 stirrer will rotate to cuvette 2 of RCT On Stirrer stirring action starts Off Stirrer stirring action stops Calibrate This option is not valid for stirrer Link First initialize stirrers and then click on link Select destination Rotate to cuvette 1 or lt Rotate to cuvette 2 Stirrer will continuously perform the stirring action for selected destination If RCT is not at offset position then stirrer will not go down in cuvette It will rotate to cuvette 1 or 2 remain up amp stirs amp come back to trough Ref VER 05 05 05 Page No 3 12 FUNCTIONAL DESCRIPTION Sample tray 1 Initialize Sample tray disturbs it s home position 4 rotates again to achieve the home position 2 Rotate 50 sample tray will take one complete rotation 3 Rotate 1 Sample tray will rotate one sample position 4 Link Sample tray will rotate continuously If there is any problem in ASP opto setting then rotation will stop 6 Samp Barcode scan This command is used to scan all 50 barcode tubes Reagent tray 1 Initial
32. 20 ml 50 REAGENT BOTTLE 50 ml 2 ADAPTER FOR SAMPLE CUPS TUBES ADAPTER FOR SAMPLE CUPS WITH 25 ADAPTORS FOR 20 ml BOTTLES REAGENT TRAY COVER SAMPLE ROTATING TRAY ASSY 51 100 OPTIONAL 1 EMERGENCY SAMPLE TRAY STANDARD PLATE 1 SAMPLE TRAY STANDARD PLATE 1 Ref CMX VER 05 05 05 Page No 5 2 INSTALLATION REAGENT amp SAMPLE BAR CODE LABLES P M KIT CONTAINING CUVETTE DRIER CRU F1 TUBING S CRU WASTE TUBING PHOTOMETER LAMP ASSEMBLY FUSES LAUNDRY PROBE CLEANER PLASTIC TOOL BOX UNIT UNPACKING INSTRUCTION SHEET UNIT INSTALLATION INSTRUCTION SHEET BARCODE STICKER DETAILS 7 Sheets Ref CMX VER 05 05 05 A A 410 1 5 3 Installation CHEMIX 800 SERVICE MANUAL 5 2 UNPACKING THE ANALYSER CAUTION Unpack the Analyser carefully otherwise you can damage accurately adjusted optical and electronic assemblies NOTE The Analyser should be unpacked only under the supervision of a Sysmex Transasia factory trained Engineer The CHEMIX 800 is fully tested before shipment and is packed carefully to prevent any shipping damage It is responsibility of customer to inspect all cartons upon arrival and notify the carrier of any apparent damage CHEMIX 800 is shipped in one wooden carton box and an additional 1 or 2 carboard boxes one contains the main unit and other has computer trolley and the accessories The main unit and accessories are packed in separate cartons Reage
33. 40 Ref CMX VER 05 05 05 Page No 5 12 INSTALLATION 5 5 COMPUTER SETTINGS NOTE If the computer is shipped with the analyser it comes factory set and no changes to the setting are required at the time of installation NOTE Changes to the computer setting other than those that have been factory set or recommended could cause severe analyser malfunctioning IMPORTANT In the computer settings the keyboard setting amp regional language settings has to be set only to the United States format NOTE There should not be any screen saver or other programmes and Software packages like games etc loaded onto the Computer as these could severely restrain the existing resources of the computer To prevent the CHEMIX 800 PC from getting infected by a virus it is recommended that no additional software package should be loaded and the use of the floppy drive should be restricted only to patient result and test back up only after verifying that the floppy disc are free from virus NOTE Power on the computer and verify proper function please verify and make sure that the computer has the following settings 1 In the computer settings the keyboard setting amp regional language settings has to be only set to United States 2 There should be no screen saver or games loaded NOTE If the computer is supplied with the analyzer then the CHEMIX 800 software comes pre loaded also the computer settings are factory set and no chang
34. 5 ID 1 00RMEGIO00135NIBN Tubing 5 5 2 2 QUICK CONNECTOR WITH SEALING RING O 1 8 1 00RMEGI000145NIBN 5523 re with 1 4 Hex to 200 Series Barb 1 16 1 5 mm ID 1 00RMEGIO00135NIBN 5524 with 1 4 Hex to 200 Series Barb 1 16 1 5 mm ID 1 00RMEGIO00135NIBN 5525 with 1 4 Hex to 200 Series Barb 1 16 1 5 mm ID 1 00 000135 5 5 3 CRU MANIFOLD 1 553 1 5 8 Thread with 1 4 Hex to 200 Series Barb 1 16 1 5 mm ID 1 00RMEGIO00135NIBN Tubing 5 5 3 2 QUICK CONNECTOR WITH SEALING RING O 1 8 1 00RMEGIOO00145NIBN 5533 with 1 4 Hex to 200 Series Barb 1 16 1 5 mm ID 1 00RMEGIO00135NIBN 5534 with 1 4 Hex to 200 Series Barb 1 16 1 5 mm ID 1 00RMEGIO00135NIBN 5535 with 1 4 Hex to 200 Series Barb 1 16 1 5 mm ID 1 00 000135 5 6 1 8 27 Thread Elbow with 7 16 Hex to 200 Series Barb 1 4 5 6 1 6 25 mm ID Tubing 1 00RMEBTO000341NICN 5 7 RGT 574 1 8 27 NPT Thread Elbow with 7 16 Hex to 200 Series Barb 1 4 1 00RMEBTO00341NICN 6 25 mm ID Tubing 10 3 CUVETTE RINSING UNIT The CRU consists of a eight stage laundry as shown in Fig 10 2 the first stage consist of three probes the two probes are used to aspirates the Bio hazardous waste from the cuvette and the third probe dispenses detergent into the cuvette The next five stages having three probes each two probes are used to aspirates the waste from cuvette and the third probe dispen
35. 5 1 ISE UNIT Straight Through Reduction Connector with 500 Series Barbs 1 8 5 1 2 3 mm and 1 16 1 5 mm ID Tubing 00RMEBT000355NICN 5 2 LAMP ASSEMBLY 5 3 TROUGH UNITS 5 3 1 SPT TROUGH 5311 He with 1 4 Hex to 200 Series Barb 1 16 1 5 mm ID OORMEGI000135NIBN 1 8 27 NPT Thread with 7 16 Hex to Classic Series Barb 1 4 5 3 1 2 6 25 mm ID Tubing 0 000344 5 3 2 2 5321 r with 1 4 Hex to 200 Series Barb 1 16 1 5 mm ID OORMEGI000135NIBN 1 8 27 NPT Thread with 7 16 Hex to Classic Series Barb 1 4 5 3 2 2 6 25 mm ID Tubing 0 000344 5 3 3 R1PT TROUGH 5 331 with 1 4 Hex to 200 Series Barb 1 16 1 5 mm ID OORMEGIO00135NIBN 1 8 27 NPT Thread with 7 16 Hex to Classic Series Barb 1 4 5 3 3 2 6 25 mm ID Tubing 0 000344 5 3 4 STIRRER 1 TROUGH 5341 with 1 4 Hex to 200 Series Barb 1 16 1 5 mm ID 1 00RMEGIO00135NIBN 1 8 27 NPT Thread with 7 16 Hex to Classic Series Barb 1 4 5 3 4 2 6 25 mm ID Tubing 1 00 000344 5 3 5 STIRRER 2 TROUGH 5351 with 1 4 Hex to 200 Series Barb 1 16 1 5 mm ID 1 00RMEGIO00135NIBN 1 8 27 NPT Thread with 7 16 Hex to Classic Series Barb 1 4 5 3 5 2 6 25 mm ID Tubing 1 00IRMEBT000344NICN 5 4 WASTE MANIFOLD 1 8 27 NPT Thread Elbow with 7 16 Hex to 200 Series Barb 1 4 5 4 1 6 25 mm ID Tubing 1 00
36. Component failure on board Replace board Low Slope 1 Misalignment of sensors Remove and replace sensor to reseat Naor 4 2 Deterioration of Calibrator Replace Cal B first and retest If still low mV decade luti Asd retest CI lt 35 solutions replace Cal A and retes mV decade 3 Deterioration of sensing electrode Replace problem sensor and test Or 4 Air bubble on reference electrode Remove electrode tap to dislodge bubble High Slope membrane replace and recalibrate Na or K gt 63 5 Deterioration of reference electrode Replace reference electrode and retest mV decade CI gt 60 IS CRANE Replace CL electrode only and retest mV decade electrodes 7 Module or Fluid temperatures Monitor temperature Change instrument exceed 37 location if ambient is too great Noise Error Flag 1 Deterioration of sensing electrode Replace problem sensor and test Single electrode 2 Electrical noise spike from environmental source a Check for electrical noise coincident with activation b Component failure on module board Replace board Noise Error Flag 1 Deterioration of reference electrode Replace reference electrode and retest Multipl a Check for electrical noise coincident electrodes 2 Electrical noise spike from with activation environmental source b Component failure on module board Replace board Drift Error Flag
37. DEIONISED WATER CAN Bi CLEAN THE CLEANING SOLUTION CAN CLEAN THE LEVEL SENSING PLATFORM CHECK THE LEVELS OF CAL A SOLUTION REPLACE IF REQUIRED CLEAN THE ANALYSER EXTERNAL SURFACE CLEAN THE COMPUTER TROLLEY MONITOR KEYBOARD AND PRINTER EXTERNAL SURFACE CLEAN THE AREA AROUND THE ANALYSER DISARD ANY UNWANTED ITEM MAINTAIN PROPER ROOM CLEANLINESS 10 CLEAN THE SAMPLE REAGENT 1 amp REAGENT 2 PROBES 11 CLEAN THE STIRRER PADDLES 12 CLEAN THE LAUNDRY PROBES 13 CLEAN THE SAMPLE TRANSPORT 14 CLEAN THE REAGENT TRANSPORT 15 CLEAN THE SAMPLE REAGENT 1 AND REAGENT 2 SYRINGE 16 CLEAN THE ANALYSER FANS 17 CLEAN THE BAR CODE READER 18 PERFORM AN AUTO SPAN CHECK AND NOTE DOWN THE GAIN VALUES FOR 340 WAVELENGTH 19 PERFORM A CUVETTE RINSE 20 PERFORM A PRECISION CHECK AND NOTE DOWN THE CV FOR AN END POINT AND KINETIC TEST 21 REPLACE THE LAMP 22 CLEAN THE ANALYSER INTERNAL SURFACE FREE OF DUST 23 PERFORM AN AUTO SPAN CHECK AND NOTE DOWN THE GAIN VALUES FOR 340 WAVELENGTH 24 PERFORM A CUVETTE RINSE 25 PERFORM A PRECISION CHECK AND NOTE DOWN THE CV FOR AN END POINT AND KINETIC TEST 26 CARRY OUT A SITE VERIFICATION FOR TEMPERATURE LINE VOLTAGE ELECTRICAL GROUND VENTILATION EXTERNAL INTERFERENCES ROOM LIGHTING AND LABORATORY CLEANLINESS PRACTICE AS DE
38. Pup p mT 310 HAZ 3 35 ne SYRINGE UNITS 2 0 coNTRoL l CONTRE ELEMENTS di is ELEMENTS 1 0 INLET OUTLET 2 mm TRANSASIA BIO MEDICALS LTD mann irm 99 99 mu aw oo LIST OF COMPONENTS USED IN HYDRAULICS OF CHEMIX 800 Sr No DESCRIPTION QTY CODE 1 0 INLET and OUTLETS 101 Quick Change inline coupling body HOSE BARB with shut off for 1 00RMEBT000354NICN 3 16 ID tubing 1 0 10 1 8 HB valved panel mount insert 1 00RMEBT000340NICN 10 11 THREAD TO BARB ADAPTER FITTINGS 3 8 NPT for 3 8 ID 1 00 Tubing ELDON JAMES 6 WN IRMEBTO000362NICN 10 12 1 16 27 NPT Thread with 5 16 Hex to 200 Series Barb 1 8 3 mm ID 1 00RMEBT000339NICN Tubing 1 0 13 SELF LOCKING FERRULES 16 SQMM 6 00RMEOTO001 101 PLCN 1 0 14 SELF LOCKING FERRULES 25 SQMM 2 00RMEOTO001 102PLCN 1 0 15 SELF LOCKING FERRULES 35 SQMM 2 00RMEOTO001 103PLCN 1 0 2 Coupling Inserts 3 16 HB HOSE BARB Shutoff 1 008RMEBTO000348NICN 103 Insert Pipe Thread Shutoff 3 8 NPT 3 8 ID 9 5mm ID 1 00RMEBTO000346NICN 1 0 4 Coupling Body 3 8 HB Hose Barb for 3 8 ID 9 5mm tube 1 00RMEBTO000345NICN 105 Change inline coupling body HOSE BARB with shut off for 1 00RMEBTO000353NICN 1 8 ID tubing 1 0 6 Coupling Inserts 1 16 HB HOSE
39. SPECIFICATIONS Ion selective electrode ISE unit optional Item Description Type of measurement selective electrode e Direct measurement for Serum samples e Urine sample to be diluted with urine diluent on board on Reagent Tray Sample types Serum and Urine 10 times diluted on board on Reagent Tray Test items K Measurement cycle Serum 40 seconds sample Urine 90 seconds sample Accessories Consumables Item Description Installation parts Standard tray Disc 1 and Disc 2 STAT Sample tray e Wash solution reservoir e Waste reservoirs Water supply reservoir Alkaline wash solution Acidic wash solution Detergent wash solution Sample probe wash solution Printer paper Barcode labels Sample cup tubes Halogen lamp ISE electrodes ISE calibrant and cleaning solutions ISE pump tubes Consumables Ref VER 05 05 05 Page No 1 13 Introduction amp Specifications Introduction amp Specifications CHEMIX 800 SERVICE MANUAL 1 3 Computer Specifications and Setup Minimum Computer Requirements Processor Intel Pentium IV amp above Memory 512 MB SD RAM Hard Disk 40 GB or higher External drive 1 44 MB FDD amp 52X CD ROM Console 15 inch Colour Monitor Keyboard Standard Mouse Standard Interface 2 X RS 232 ports Operating system Windows XP Printer Epson LX 300 dot
40. Senor The connecters up down motor syring dunno Tun opto sensor out put has to be checked and verified R2 Arm 41 R2PT up down error The connecters up down motor durne initialization upopto sensor home opto sensor out put has to be checked and verified 42 R2PT Rotational Error The connecters rotational motor during initialization upopto sensor home opto sensor Ref CMX VER 05 05 05 Page No 13 2 ERROR CODES LIST Assembly Error Error Message Trouble shooting Tips Code direction opto sensor out put has to be checked and verified 43 R2PT Up Down Error The connecters up down motor during run upopto sensor home opto sensor out put has to be checked and verified 44 R2PT Rotational Error The connecters rotational motor during run upopto sensor home opto sensor direction opto sensor out put has to be checked and verified 45 R2PT Arm VOD Error The connecters VOD opto sensor placement of reagent bottles arm position in cuvette arm position in trough has to be checked and verified 46 Reagent 2 Absent The connecters LLS board has to be checked and verified R2 Syringe 61 R2pt syringe up down The connecters up down motor syring error during initialization opto sensor out put has to be checked and verified 62 R2 Syringe Up Down The connecters up down motor syring Error during run opto sensor out put has to be checked and verified Sample Arm 71
41. Sensor UP DN Motor UP DN Home Position Sensor TRANSASIA BIO MECICALS LTO IT MEASURE mm v vy vvvv ees er em T s m so sor 2 9 2 SAMPLE SPP REAGENT 1 R1PP AND REAGENT 2 R2PP DILUTOR ASSEMBLY A Funtion The SPP R1PP R2PP Dilutor assemblies enable the respective arm assemblies to aspirate dispense respective liquids i e Air Sample Standard Control Warm DI water in the case of SPP Air Reagent Warm Di Water in the case of R1PP and R2PP B Components of SPP R1PP R2PP Dilutor Assemblies Component Function Operation Up Down Motor Stepper Motor Imparts Up Dn motion to the Dilutor assembly Up Home Position Sensor Opto Interruptor For sensing the Home Position of the Dilutor Actuator Up Position Plunger Moves up and down upon receiving appropriate command DI water Valve Not shown in the figure Solenoid operated valve meant for controlling the operational flow of warm DI water to the probe Syringe In the normal operation when the DI water valve is closed the Sample Standards Controls are aspirated dispensed by the action of the syringe When the DI water valve is open the syringe is in the UP position so that the warm water from the Pressure tank flows through the syringe to the inner side of the probe to facilitate cleaning of the inner wall
42. Tr Coda A FIRST ASSEMBLE THE RCT ASSEMBLY ON CASTING PLATE THEN FIX ASSEMBLEY PROCESS PR 84 d ATER JACKET WATER JACKET SPACER IRMKDMNCAUM ____________ HEXAGONAL SORET HEAD CAP BY 62 LAMP n BE RED TODO TAME 11 Lamp Terminals Water jacket Rotation Motor Slipring assembly Home Rotation Position sensgrs LL NE m RCT ASSEMBLEY PROCESS PR 05 WITHOUT THE THE ATT 9 8 PRESSURE TANK VESSEL ASSEMBLY C Function The main purpose of the pressure tank assembly is to provide warm water at constant pressure to the SPT R1PT R2PT Probes CRU Laundry Section and to the troughs of SPT R1PT and R2PT To achieve this purpose the pressure tank assembly is provided with a resistance heater a pressure gauge a thermostat a pressure transmitter and a thermal cutoff switch To maintain the pressure inside the pressure tank a pressure regulator is mounted in the hydraulic line To maintain the temperature of DI water inside the pressure tank a thermostat is provided And to monitor the pressure of DI water inside the pressure tank a pressure transmitter is mounted Component Function Operation Pressure Tank Stainless Steel fabricated pressure tank to contain hot DI water at pressure Pressure Gauge
43. Tubing 4 0 8 Tee Connector with Classic Series Barbs 1 8 3 mm ID Tubing 1 00RMEBTO000360NICN 4 0 9 Connector with Classic Series Barbs 1 8 3 mm ID Tubing 1 00RMEBTO000360NICN 4 1 PULSATION DAMPER 1 008RMEGIO000126NIBN 4 1 1 Swivel Elbow 3 8 BSPT for tube OD 5 16 1 00RMEBTO000359NICN 4 1 2 Swivel Elbow 3 8 BSPT for tube OD 5 16 1 00RMEBTO000359NICN 4 10 CKD VALVE TYPE 21 01 03A 100V 1 00RMEV A000002NIBN 4 10 1 Thread To Barb Adapter Fittings 1 8 Bspt 1 8 L2 1 00RMEBTO000368PICN 4 10 2 Thread To Barb Adapter Fittings 1 8 Bspt 1 8 L2 1 00RMEBTO000368PICN 4 11 CKD VALVE TYPE 21 01 03A 100V 1 A000002NIBN 4 11 1 Thread To Barb Adapter Fittings 1 8 Bspt 1 8 L2 1 00RMEBTO000368PICN 4 11 2 Thread To Barb Adapter Fittings 1 8 Bspt 1 8 L2 1 00RMEBTO000368PICN 4 12 PRESSURE GAUGE 1 00 8RMEGI000093NLBN PRESSURE TRANSMITTER 1 00RMESE000001NLAN 4 2 PRESSURE TANK 1 00 423 Thread with 5 16 Hex to 200 Series Barb 1 8 3 mm 1 00RMEBTO000339NICN 424 dE Thread with 5 16 Hex to 200 Series Barb 1 8 3 mm 1 00RMEBTO000339NICN 425 Thread with 5 16 Hex to 200 Series Barb 1 8 3 mm 4 42 6 De Thread with 5 16 Hex to 200 Series Barb 1 8 3 mm 4 4 3 PRESSURE REGULATOR 1 00RMEVAO000004NIBN 4 3 1 Swivel Elbow 1 8 BSPT for tube OD 5 16 1 00 000358
44. be compatible with the local electrical sockets of some Countries please to have these NOTE procured from the local market prior to the installation Before powering ON the analyser verify and confirm that all ISE electrodes have been NOTE properly installed their walls are flush against each other with the rubber O rings in place Ref CMX VER 05 05 05 Page No 5 17 Installation Installation CHEMIX 800 SERVICE MANUAL Locate and pull open in the direction towards you the L H S door for access to ISE power supply PCB Locate and connect the 2 pin power connector to the ISE power supply PCB The Analyser is shipped with the 2 pin power connector to the ISE power supply PCB disconnected NOTE This is done in order to prevent accidentally powering on the ISE module without the Electrodes connected Before powering up the analyser fit all ISE electrodes connect ISE CAL A bottle and tubes only after doing so connect the 2 pin power connector to the ISE power supply PCB After carrying out the above mentioned electric verifications connect the power chord to the analyzer computer and monitor Locate and power ON the rear power switch on the back panel of the analyser and confirm that the reagent cooling fan has started rotating also touch and physically verify the cooling of the reagent tray also verify from the sound that the ISE pumps have started priming Locate and power ON the switch on the right sid
45. case of problems beyond the scope of the service engineer Transasia is available for assistance and at the following Transasia Bio Medicals Ltd 8 TRANSASIA HOUSE ADDRESS CHANDIVALI STUDIO ROAD Mumbai 400072 PHONE Q 491 22 2857 4040 91 22 2857 5050 91 22 28575689 FAX 91 22 28573030 E MAIL DK tech support transasia co in Monday to Saturday TIMINGS to 5 PM IST Ref CMX VER 05 05 05 Page No 1 2 INTRODUCTION amp SPECIFICATIONS CHEMIX 800 The CHEMIX 800 designed with the needs of modern clinical laboratories in mind it easily fits into any laboratory environment The CHEMIX 800 analyser is a fully automated random access time optimised patient sequential discrete computerised chemistry analyser Once programmed it is a true walk away system The analyser features user friendly operation with minimum operator intervention It is a highly sophisticated system and therefore it is of utmost importance that the operator and service personnel read the instructions carefully and becomes familiar with the operation theory The working unit consist of a state of the art photometer and sophisticated robotics combined with an Operating Console and Data processing unit This unit is connected by an RS 232 bi directional interface To the Analyser PC the work schedule transferred from the Analyser PC to the analyser and after executing the schedule as per the programmed sequence th
46. cleaning up of cuvette B Components of SPP R1PP R2PP Dilutor Assemblies Component Function Operation Up Dn Motor Stepper Motor Imparts Up Dn motion to the CRU unit Up Sensor Opto Interruptor For sensing Home Up position of the CRU Dn Sensor Opto interruptor For sensing the Down position of the CRU A KEEUULD NE HONIZONTAL AND im Org Code Number ININMEUPTIRNBOULD MIDDLE OF TEE 1 8 W0 ASHPA MO EAU ASSEMBLY PROCESS PROCESS COMPONENT 2 M0t 96 pa 00 00 000 ASM PR 06 BE MOONT AFTER AMEMBLT TEE CRI eee PETENS CRU 1008 LT AZSEMBLY MAOCLES PR 14 ON MAINCAETINGPLATE 4 TEE COLLI ARMIN SCREW WITH PV 2 SW PROCESA GL TAKECAHEDEALLINEMENTORCNU 6 eine 7 SLOTTED CHEESE HEAD HACHME SCREWS 658 125 6 SCREW IATH PW amp SV D MARTAIN CRITICAL DIMENNON 4 Up Dn Motor Up Sensor TRANSASIA BIO MEDICALS LTD j Vv vvv Dn Sensor CRU ASSEMBLY PROCESS ff A KM MI of 000 PR f 9 4 CUVETTE MIXING 5 1 Stirrer 1 and 5 2 Stirrer 2 ASSEMBLY A Function The STR And STR2 assemblies are meant for performing the mixing operation of mixing the sample and reagent s in the cuvette When R1 and R2 both are programmed then both the u
47. data QC data Control data System switch amp Sequence Carry out a site verification for temperature line voltage electrical ground ventilation external interferences room lighting and laboratory cleanliness practice as described in chapter 16 1 SERVICING A CUSTOMER SITE Make a entry in the Customer error log book Ref CMX VER 05 05 05 Page No 12 14 PREVENTIVE MAINTENANCE 12 5 SERVICE TECHNICIAN ANNUAL MAINTENANCE LOG Name of the Customer Month From to Name of the service technician Model CHEMIX 800 Serial No Annual Maintenance clean the waste can clean the bio hazardous waste can clean and fill the deionised water can clean the cleaning solution can clean the level sensing platform check the levels of cal A solution replace if required clean the analyser external surface clean the computer trolley monitor keyboard and printer external surface Replace external tubings to the waste Bio hazardous waste cleaning solution amp Deionised water maintain proper room cleanliness clean the area around the analyse and discard any unwanted items Replace the Sample Reagent 1 amp 2 probes Replace the stirrer 1 and stirrer 2 paddles Replace the laundry probes Replace the laundry tubings clean the sample transport clean the reagent transport Clean and replace if necessary the Sampl
48. free of any trapped air bubbles Do this till the entire tubing and probe is completely primed and free of air bubbles REAGENT 1 From the SERVICE CHECK menu select REAGENT 1 ARM click on INITIALIZE click on REAGENT OUTER click on REAGENT TO CUVETTE click on CUVETTE TO DRAIN CLICK on the GO BACK button From the SERVICE CHECK menu select SYRINGES then select REAGENT 1 SYRINGE click on INITIALIZE and click on the VALVE ON Check and confirm that a clear uninterrupted straight jet of water emerges from the probe that is free of any trapped air bubbles Do this till the entire tubing and probe is completely primed and free of air bubbles Ref CMX VER 05 05 05 Page No 5 31 Installation Installation CHEMIX 800 SERVICE MANUAL REAGENT 2 From the SERVICE CHECK menu select REAGENT 2 ARM click on INITIALIZE click on REAGENT OUTER click on REAGENT TO CUVETTE R2 click on R2 CUVETTE TO DRAIN CLICK on the GO BACK button From the SERVICE CHECK menu select SYRINGES then select REAGENT 2 SYRINGE click on INITIALIZE and click on the VALVE ON Check and confirm that a clear uninterrupted straight jet of water emerges from the probe that is free of any trapped air bubbles Do this till the entire tubing and probe is completely primed and free of air bubbles Ref CMX VER 05 05 05 Page No 5 32 INSTALLATION 5 10 TEMPERATURE VERIFICATION PROCEDURE REAGENT TEMPERATURE VERIFICATION PROCEDURE Fill a 20 ML reagent bottle pla
49. index hole provided on the sample tray Place the calibration tray in position and make sure that the index pin on the Sample transport slides into the index hole provided on the Calibration tray Unpack the Reagent tray from the accessories box Hold the Reagent tray with your right hand as shown Gently place the Reagent tray into the reagent tray well Make sure that the index pin on the Reagent transport slides into the index hole provided on the Reagent tray Place the Reagent tray lid over the Reagent Tray Make sure that the index pin on the Reagent transport slides into the index hole provided on the Reagent tray Ref CMX VER 05 05 05 Page No 5 9 Installation Installation CHEMIX 800 SERVICE MANUAL Installing the Waste can Bio hazardous waste can Water can and Cleaning Solution can Please refer to figure 4 30 before carrying out this installation procedure Unpack the Liquid Level Sensing Platform from the accessories box place it behind the analyser as shown in Floor requirements chapter 3 5 there is a label on the Liquid Level Sensing Platform that says ANALYSER SIDE when installing the platform make sure that this label faces the analyser Connect the cable of the Liquid Level Sensing Platform to the D 9 connector located on the back panel of the instrument located besides the mains socket As shown in figure 4 30 From the accessory box remove the 20 litres Deionised water can 20 litres Wa
50. measured for a particular cuvette these readings are then plotted Ref CMX VER 05 05 05 2 8 PRINCIPAL OF ANALYSIS in the time course graph After 62 rotations where in every rotation a reading is recorded and the reaction is completed the washing process of the cuvette starts The complete reaction graph for every cuvette is plotted and after co relating the data from Calibration and Parameter menus the final result is calculated and displayed Cleaning process After the final reading the cuvette comes under the CRU for cleaning and the entire cycle starts again The Complete operating cycle can be described as follows The reaction disk consists of 72 reaction cuvettes arranged in circular mode The reaction disc is maintained at 37 C with the help of a dry incubation the entire disk rotates in a counter clockwise direction advancing 1 position in 10 every seconds Each reaction tray cycle has two positions a reset and offset position The first result is printed out in 10 5 minutes after sampling 10 seconds a cycle X 63 cuvette readings 630 seconds of incubation and simultaneous cuvette readings Ref CHX VER 05 05 05 2 9 Principle of Analysis FUNCTIONAL DESCRIPTION 3 Functional Description This section consists of the following 3 1 INSTRUMENT AND ACCESSORIES LAYOUT 3 2 SERVICE MENU SOFTWARE LAYOUT AND FUNCTION Ref CMX VER 05 05 05 Page 3 1 Functional
51. or distilled water Now go to SERVICE CHECK gt REAGENT 2 ARM 1 Select INITIALISE gt TO REAGENT 2 INNER gt REAGENT CUVETTE R2 The Reagent2 probes moves over to cuvette number 36 Verify that the hollow dispense needle is in the centre of the cuvette 2 Adjust the Reagent 2 probe as follows Lift and remove the probe plastic cover and locate the Allen Screw on the top end of the arm shaft Slightly loosen this Allen screw and rotate the top plate of the arm so as to position the dispense needle in the centre of the cuvette When doing this make sure that only the horizontal top plate rotates and the main vertical shaft is stationary Tighten the Allen screw 3 Verify proper centring by repeating steps 1 to 2 Select INITIALISE REAGENT INNER DOWN The Reagent 2 probe will move down into the reagent bottle number45 until it senses liquid Select INITIALISE gt REAGENT INNER REAGENT CUVETTE H2 R2 CUVETTE TO DRAIN Select INITIALISE gt REAGENT INNER gt REAGENT CUVETTE R2 gt R2 CUVETTE TO DRAIN DRAIN TO TROUGH Ref CMX VER 05 05 05 REMARKS OBSERVATIONS fe Verify that the Reagent probe dispense needle is at the centre of cuvette R2 number 36 NOTE Take care that the centring is not disturbed while tightening the Allen screw NOTE The Reagent 2 arm verification on the reagent tray is done only for Reagent inner at position number 45 Verify that the probe is at the centre of
52. part houses the ASP Contains a window to facilitate barcode reading of the samples Barcode Reader Mounting Meant for mounting the Barcode reader Bracket Sample Tray Assembly Assembly of Sample Tray m 7 Cade Bah bpm STEHT DE 17 03 0 00 000 ASH PR 04 ASP ASSEMBLY PRESS 101 THE CENTER OF THE PT Assy Barcode reader __ SUNITED HEAD SCHEWS MES X SCREW WITH PW SW Mounting amp 532 ASSY 4 SLOTTED CESE HEAD SCREWS O50 MES X 5 SC OOM READER 2 Sensor sensor EM TRANSASIA BID MEIBCALS E a a 1 2 T AI MANTAN 0001 0111 SR 3 3 Emergency 4 RWITASMN 0 68 Tray 5 __________ ee mvoevanpvassarmsesmn 1 esere Seme jew SSC Sa 1 a A FOLLOW ABOVE SEQUENCE FOR EMERGENCY SAMPLE TRAY 51 100 ASSY AND FOLLOWING COMPONENT ONLY THAT ASSEMBLY 1 ME ENN ATE 1 NOTE A gt INSERT SAMPLE TRAY IN SAMPLE TRAY LOCATING PIN sample tray ASP CONTAINER 1
53. surrounding area should be mantained clean and regularly decontaminated to prevent contaminating yourself and others There should be no spillage of Serum Reagents Waste or Deionised water Make shure that no Reagents or Samples are placed on top of the analyser or trolley as they could spill causing a permernant damage to the Analyser MANTAINING AN ERROR LOG BOOK Maintain a log book at the customer site every visit and error reported with the date should be entered make sure that this book is updated after performing the maintenance Ref CMX VER 05 05 05 Page 12 3 Preventive Maintenance CHEMIX 800 SERVICE MANUAL 12 2 MAINTENANCE SCHEDULE DAILY MAINTENANCE Start of the day procedure 1 EMPTY WASTE CAN 2 EMPTY BIO HAZARDOUS WASTE CAN 3 FILL DEIONISED WATER CAN 4 FILL CLEANING SOLUTION CAN 5 CHECK CAL A SOLUTION LEVEL REPLACE BOTTLE IF NECESSARY 6 CLEAN THE ANALYSER EXTERNAL SURFACE 7 REPLACE PRINTER PAPER IF NECESSARY 8 CLEAN THE COMPUTER TROLLEY MONITOR KEYBOARD AND PRINTER EXTERNAL SURFACE 9 PERFORM A CUVETTE RINSE 10 PERFORM A PHOTOMETER CHECK AND VERIFY THAT THE AUTO SPAN CHECK HAS PASSED SUCCESSFULLY 11 VERIFY REAGENT TRAY TEMPERATURE 12 REPLENISH OR REPLACE REAGENTS IF NECESSARY End of the day procedure 1 REMOVE AND DISCARD ALL SAMPLE STANDARD AND CONTROLS CUPS OR TUBES FROM THE SAMPLE TRAY PERFORM A WA
54. that the beam will fall on the BC as shown in the fig 6 Repeat procedure pt no 4 and 5 to get best possible alignment and barcode read N B 1 The accurate separation between the BCR surface and the bottle surface is specified in the Figures attached here with pg 41 to 43 2 Barcode label placement on Reagent bottles is specified in the figures attached here with pg 44 Ref CMX VER 05 05 05 Page No 5 40 INSTALLATION ASP BAR CODE SCANNER DIMN Ref CMX VER 05 05 05 Page No 5 41 Installation Installation CHEMIX 800 SERVICE MANUAL ASP BAR CODE SCANNER DIMN Ref CMX VER 05 05 05 Page No 5 42 INSTALLATION 1 AR CODE D ASP Ref CMX VER 05 05 05 ASP BAR CODE SCANNER DIMN Page No 5 43 Installation Installation CHEMIX 800 SERVICE MANUAL Ref CMX VER 05 05 05 Page No 5 44 INSTALLATION SAMPLE BAR CODE LABLE DIMN Ref CMX VER 05 05 05 Page No 5 45 Installation Installation CHEMIX 800 SERVICE MANUAL Barcode Standards The Barcode can be generated using any of the following specifications 1 CODE 128 2 CODE 39 3 NW7 4 2 5 INTERLEAVED The Barcode sticker layout is for the reagent Fig a and for the sample Fig b is shown above The Barcode Sticker Placement The Barcode stickers has to be placed at a distance of 20 mm from the bottom of Reagent bottle as well Sample tube as shown in the figures pg 39 and pg 44 abo
55. the reagent bottle at position number 45 on the reagent tray Verify that the probe is at the centre of the R2PT drain Verify that the probe is at the centre of the R2PT trough Page No 5 25 Installation Installation CHEMIX 800 SERVICE MANUAL VERIFYING PROPER REAGENT 2 ARM FUNCTION Initialise the system trough the service Check menu To rotate the RCT tray to the reset position select SERVICE CHECK gt CRU amp REACTION TRAY gt REACTION TRAY gt NITIALISE gt RESET Select SERVICE CHECK gt REAGENT 2 ARM gt INITIALISE gt LINK gt REAGENT INNER gt REAGENT CUVETTE R2 The Reagent arm will move over Reagent bottle number 45 go down till it senses the liquid The syringe plunger moves down aspirating reagent from the bottle the arm then moves to the dispense cuvette position cuvette number 39 pauses and then moves to the drain position where the contents of the probe is discarded The analyser does this multiple times till the STOP button is clicked the reagent bottle is empty or an error has occurred VERIFY STIRRER ARM ALINGMENT NOTE The Stirrer arm is aligned with the RCT in the offset position NOTE The Stirrer arm alignment is done with respect to cuvette No 39 for stirrer paddle No1 and cuvette 50 for stirrer paddle No 2 and with the paddles rotating only verification is done at the other positions ACTION REMARKS OBSERVATIONS Initialise the system through the Service Check menu
56. the direction in which the correction is required when doing this make sure that only the horizontal top end rotates and the main vertical shaft is stationary Tighten the Allen screw Place the Reagent tray back in position Figure 9 1 Reagent tray 3 Allen screws qu A Centre Shaft Ref CMX VER 05 05 05 Page No 5 29 Installation Installation CHEMIX 800 SERVICE MANUAL 5 9 VERIFYING PROPER HYDRAULICS FUNCTION LOAD CELL VERIFICATION PROCEDURE ACTION OBSERVATIONS RESULT Place the 20 Ltrs Can with only 2 Ltrs of water in it on the DI The buzzer should turn ON and the LED marked water tray Water should blink The buzzer should turn OFF and the LED marked Water should go OFF Place 10 Ltrs can with only 1 5 Ltrs of water in it on the The buzzer should turn ON and the LED marked DET Cleaning soln tray should blink Apply slight pressure on the can The buzzer should turn OFF and the LED marked Det should go OFF Place the 10Ltr can with only 7 5 Ltrs of water in it on the Haz The buzzer should turn ON and the LED marked Haz Waste tray Waste should blink Remove about 0 5 Ltrs of water from the can The buzzer should turn OFF and LED marked Haz Waste should go OFF Place the 20 Ltr can with only 17 5 Ltrs of water in it on the The buzzer should turn ON and the LED marked Waste tray Waste should blink Remove about 1 Ltr of water from the can
57. the prism on the opposite side were allowed to fall on a screen we would see a wide spectrum of colors beginning with red on the top and ending with violet at the bottom The colors visible in between are in the order of indigo blue green yellow and orange Visible white light Red Orange Yellow Green Blue Indigo Violet Incident or white light contains the entire spectrum objects that appear colored absorb light at a particular wavelength and reflect others thus giving different colors That is color is a function of its wavelength Light having a wavelength of less than 400 nm is termed Ultraviolet where as light having a wavelength greater than 800 nm is described as Infrared both ultraviolet and infrared lights are invisible to the human eyes Light corresponding to wavelengths between 400 nm and 800 nm is visible to the human eye and is termed as Visible light Holographic Grating Incident white light A 4 Light slit Spectrum Photodiode Array Ref CMX VER 05 05 05 No 2 2 PRINCIPAL OF ANALYSIS Principals of Absorption Photometry Beer s Law If Light is allowed to pass trough a colored solution the solution will absorb some light while the rest of it will be transmitted The amount of light absorbed is proportional to the nature concentration and color of the solution Light absorbed Concentration of the solution Lambert s Law The light absorbed by the colored solution is directly
58. wall VERIFY SAMPLE TRAY ALINGMENT The X axis is aligned using the Sample arm alignment procedure The Y axis is aligned using the Sample Tray alignment procedure Y axis ACTION Sample cup No 1 Initialise the system through the Service Check menu SERVICE CHECK SAMPLE ARM ALIGN SAMPLE OUTTER Place a sample cup filled with tap water in sample positions number 1 on the sample tray and positions S1 amp B1 on the standard tray As tap water has ions for conduction Do not use deionised or distilled water 1 Select SERVICE CHECK SAMPLE ARM INITIALISE gt SAMPLE OUTER gt DOWN The Sample probes moves down until it senses the present of liquid in the Cup No 1 and then stops Verify that the dispense needle is in the centre Ref CMX VER 05 05 05 REMARKS OBSERVATIONS Sample probe dispense needle is at the centre of sample cup No 1 Page No 5 27 Installation Installation CHEMIX 800 SERVICE MANUAL of the cuvette 2 Select SERVICE CHECK gt INITIALISE gt Adjust the sample tray as follows NOTE Take care that the centring is not 3 Lift and remove the sample tray locate the 3 Phillips disturbed while tightening the Phillips screws Screw on the centre shaft 4 Slightly loosen the three Phillips screws and slowly rotate the top plate of the shaft in the direction in which the correction is required when doing this make sure that only the horizontal top plate rotates a
59. you do not damage the paddles once you have reached the top most position rotate it and position it over the trough Remove the protective material Gently slide the CRU arm upwards to the top most position making sure you do not damage the probes and remove the protective material and clean debris Ref CMX VER 05 05 05 Page No 5 7 Installation CHEMIX 800 SERVICE MANUAL 5 3 INSTALLING THE ANALYSER To avoid a shock hazard ground the Analyser Computer Printer and Monitor using a 3 pin grounded electric outlet Do not use an adapter as it could cause a loose contact and improper grounding Confirm that all cuvettes have been fitted properly into their respective slots on the reaction tray and none of them are jutting out c Confirm that all cuvettes have been fitted properly into their respective slots on the reaction 5 tray and none of them are jutting out n When removing or placing the cuvettes into their slots make sure that you grip them NOTE by their sides and top end never let the fingers or any sharp Objects come in contact with the optical area Ref CMX VER 05 05 05 Page No 5 8 INSTALLATION Installing the Sample tray Reagent tray and Cuvette reaction tray Unpack the Sample tray from the accessories box Hold the sample tray with your right hand Gently place the sample tray into the Sample tray well Make sure that the index pin on the Sample Transport slides into the
60. 00 SERVICE MANUAL 9 Mechanical Description This section consists of the following 9 0 GENERAL 9 1 SAMPLE REAGENT 1 AND REAGENT 2 ARM ASSEMBLY 9 2 SAMPLE REAGENT 1 AND REAGENT 2 DILUTOR ASSEMBLY 9 3 CUVETTE RINSING UNIT ASSEMBLY 9 4 CUVETTE MIXING STIRRER ASSEMBLY 9 5 SAMPLE TRANSPORT ASP ASSEMBLY 9 6 REAGENT TRANSPORT ASSEMBLY 9 7 REACTION TRANSPORT RCT ASSEMBLY 9 8 PRESSURE TANK VESSEL ASSEMBLY 9 9 LEVEL SENSING PLATFORM ASSEMBLY Mechanical description 9 0 GENERAL This chapter explains the operation of each of the mechanical assemblies of the analyzer Some of the assemblies are similar to one another For example R1PT R2PT AND SPT R1PP R2PP AND SPP RGT AND ASP 9 1 SAMPLE SPT REAGENT 1 R1PT AND REAGENT 2 R2PT ARM ASSEMBLY A FUNCTION When the analyzer is initialized the Sample Reagent 1 and Reagent 2 pipettes position themselves at the respective trough position Home positions for the Arm Assemblies R1PT pipettes the reagent from R1 bottle placed in the Reagent Tray and dispenses in the cuvette Then the Arm positions to the Trough position and the R1 Probe is cleaned with warm DI water internally and externally at the trough position Similarly R2PT pipettes the reagent from R2 bottle placed in the Reagent Trayand dispenses in the cuvette Then the Arm positions to the Trough position and the R2 Probe is cleaned with warm DI water internally and externally at the trou
61. 002 RO The Stepper Motor Drive SMD card consists of 4 similar sections of motor driver circuit to drive 4 stepper motors The typical motor used by us is MAE 200 2220 The winding resistance of the motor is 11 2E Each section requires two signals to operate viz clock and direction Five Motor drive card are used in CHEMIX they are located in the backplanel The flow of the logic input signals clock and direction is from the Interface board to Base board1 to Backplanel to motor Drive board The flow of the output signals is from motor Drive board to Backplanel to the motors The CPLD in the motor driver card has to be programmed before using it for driving the motors 7 15 DC DRIVE PCB ELS32004 R1 The DC drive card accepts logic signals from FPGA to turn ON OFF the DC valve pump each card is capable of driving eight valve pump One DC drive card is used in CHEMIX it is located in the backplane2 The flow of the logic input signals is from the Interface board to Ref CMX VER 05 05 05 Page No 7 3 Electronic Circuit description Electronic Circuit description CHEMIX 800 SERVICE MANUAL Base board1 to Backplane2 to DC Drive board The flow of the output signals is from DC Drive board to Backplane2 to the valves and pumps 7 16 ISPS ELS22019 RO It s a power supply board for the ISE module Accept 15V DC input and generates 12V 1A supply for the ISE module This PCB is located near the ISE module 7 17 AC
62. 04 ELECTRICAL DESCRIPTION sim 0 008 XIN3HO NO 0350 1 LJ ASSV YILVIH LOU ZL000 Ivannn 11111111 ALI STVOITHW OIH VISVSNVAL 3009 NOILVfYISNI HLIM S LO3SIM NO 1331 AMIM ININOO H LON3 1 ALIHM ON ANO I3d OlA anid Nid 144 8 9 80 15 SINHO IN 00L SONVLSISSY 6 21 TvIH31VIN ONLLV3H 009 IVIMILVIA SNILVSH 40 0091 IVIMALVINA 9NILV3H UMOUS SV JO UONEJUSUO UOnegJosep Spee uoisueuulq 5109 JO ON SLLVM 0 OVA Or yoede rr m w CHEMIX 800 SERVICE MANUAL 1 ELSS2D15 RO BASE BOARD1 WIRING id 1 emm ________ 5 E 1 ELECTRICAL DESCRIPTION Oddy Alva 3NOZ vc0SSOM SIN DI ON 5 60 82 NUO ONIMIM 2 ISVA LY 8002SS1A Z 000 IVEAnN IIILLLLLI GLI SIVOITQHA OIH VISVSNVUI M38AnN 3009 04808 3293831 1 01
63. 06 R0 7 4 PHOTOMETER ELS52013 R0 7 5 LSH PCB ELS52009 R1 7 6 LSS PCB ELS52010 R2 7 7 BACKPLANE 1 ELS52005 R1 7 8 BACKPLANE 2 ELS52014 R1 79 INTERFACE PCB ELS32002 R2 7 10 BASE BOARD 1 ELS52015 R0 7 11 BASE BOARD 2 ELS52008 R0 712 STIRRER PCB ELS32006 R1 713 RCT ELS52004 R0 7 14 MOTOR DRIVE ELS52002 R0 7 15 DC DRIVE ELS32004 R1 7 16 ISPS ELS22019 R0 7 17 AC DRIVE BOARD ELS32003 R0 7 18 WGPTO3 8 ELECTRICAL WIRING CONNECTIONS 9 MECHANICAL DESCRIPTION 9 0 GENERAL 9 1 SAMPLE REAGENT 1 AND REAGENT 2 ARM ASSEMBLY 9 2 SAMPLE REAGENT 1 AND REAGENT 2 DILUTOR ASSEMBLY 9 3 CUVETTE RINSING UNIT ASSEMBLY 9 4 CUVETTE MixiNG STIRRER ASSEMBLY 9 5 SAMPLE TRANSPORT ASP ASSEMBLY 9 6 REAGENT TRANSPORT ASSEMBLY 9 7 REACTION TRANSPORT RCT ASSEMBLY 9 8 PRESSURE TANK VESSEL ASSEMBLY 9 9 LEVEL SENSING PLATFORM ASSEMBLY 10 HYDRAULIC DESCRIPTION 10 1 HYDRAULICS SYSTEM OPERATION 10 2 HYDRAULICS DIAGRAM 10 3 CUVETTE RINSING UNIT 11 HYDRAULIC CALIBRATION PROCEDURE 11 1 PRESSURE TANK ADJUSTMENT PROCEDURE 11 2 LAUNDRY FLOW ADJUSTMENT PROCEDURE 11 3 RI R2 amp Sample Probe Dispense Verification 12 PREVENTIVE MAINTENANCE 12 1 SERVICING A CUSTOMER SITE 12 2 MAINTENANCE SCHEDULE Ref CMX VER 05 05 05 Contents page 2 CHEMIX 800 SERVICE MANUAL 12 3 USER DAILY amp WEEKLY MAINTENANCE LOG 12 4 SERVICE TECHNICIAN QUARTERLY MAINTENANCE LOG 12 5 SERVICE TECHNICIAN ANNUAL MAI
64. 1NICN 3 2 4 LOW PRESSURE STANDARD UNION 1 00RMEBTO000352NICN 3 3 RIPT SYRINGE 331 mua Thread with 5 16 Hex to 200 Series Barb 1 16 1 5 mm ID 1 00RMEGI000149NIBN 3 3 2 FERRULE P 353 1 00RMEOT001047PICN 3 3 2 FERRULE NUT P 308 1 00RMEOT001048PICN 3 3 3 FERRULE P 353 2 00RMEOTO001047PICN 3 3 3 FERRULE NUT P 308 1 00RMEOT001048PICN 3 3 3 LOW PRESSURE STANDARD UNION 1 00RMEBT000352NICN 3 4 R2PT SYRINGE 341 1 4 28 UNF Thread with 5 16 Hex to 200 Series Barb 1 16 1 5 mm ID 1 00 Tubing RMEGI000149NIBN 3 4 2 FERRULE P 353 1 00RMEOTO001047PICN 3 4 2 FERRULE NUT P 308 1 00RMEOT001048PICN 3 4 3 FERRULE P 353 2 00 1047 3 4 3 FERRULE NUT P 308 1 00RMEOT001048PICN 3 4 3 LOW PRESSURE STANDARD UNION 1 00RMEBTO000352NICN 3 4 4 FERRULE P 353 2 00RMEOTO001047PICN 3 4 4 FERRULE NUT P 308 1 00RMEOT001048PICN 3 4 4 LOW PRESSURE STANDARD UNION 1 00RMEBTO000352NICN 3 5 PUMP 24V DC 1 BAR PRESSURE 1 00RELPUOO0005NIBN 3 6 PUMP 24V DC 1 BAR PRESSURE WITH REGULATOR 1 00RMEOT000882NIBN PUMP 100 50 60 Hz FLOW RATE 6 MAX PRESSURE 98 3 7 kPa MAX VACUUM 59 9 kPa 1 00RELPUOO0006NIAN 3 7 1 Swivel Elbow 1 8 BSPT for tube OD 1 4 1 00RMEBT000357NICN 3 7 2 Swivel Elbow 1 8 BSPT for tube OD 1 4 1 00RMEBT000357NICN 3 7 3 Swivel Elbow 1 8 BSPT for tube OD 1 4 1 00RMEBT000357NICN 3 7 4 Swivel Elbow 1 8 BSPT for tube OD 1 4
65. 2 rotational error M duse direction opto sensor out put has to be 5 checked and verified B3 The connecters up down motor Stirrer2 up down error duane tin upopto sensor out put has to be checked and verified B4 The connecters rotational motor home Stirrer2 rotational error MOM diving direction opto sensor out put has to be checked and verified CRU Cl CRU Up Down The connecters up down motor Movement Error during upopto sensor down opto sensor Initialization out put has to be checked and verified C2 CRU up down error The connecters up down motor during run upopto sensor down opto sensor out put has to be checked and verified RCT RCT rotational error The connecters stop opto base opto during initialization outputs has to be verified Consider the interlock effects while trouble shooting E2 RCT Rotational Error The connecters stop opto output has to be verified Consider the interlock effects while trouble shooting Ref CMX VER 05 05 05 Page No 13 1 Error Codes List Error Codes List CHEMIX 800 SERVICE MANUAL Assembly Error Error Message Trouble shooting Tips Code Miscellaneous Fi Insufficient DI Water Check the DI water level sensor output of load cell Check Water Pressure Check the pressure unit for its functioning any leakage block in the tubing RGT cover switch Check the cover placement the logic closed open leve
66. 3 HAZARDOUS MATERIAL WARNING ABOUT PLACES WARNING On the Biohazardows waste can 10 Lt THE TANK CONTAINS HAZARDOUS On the Waste Can 2014 MATERIAL SAFTY WARNINGS 2 MAST HEMIX WARNING ABOUT PLACES WASTE On Waste Can 20 Lt WARNING ABOUT PLACES CLEANING SOLUTION On Cleaning Solution Can 10 Lt DI WATER WARNING ABOUT PLACES DI WATER On DI water Can 20 Lt SAFTY WARNINGS 3 HEMIX WARNING FOR SAFE USE During operation do not touch auto sampler unit reagent container unit nozzles and any other moving mechanical parts in the analyzer During operation shut cover all the time Never touch patients samples with bare hands to prevent operator from possible infection Handle SPT nozzle RPT nozzle reaction cells wash nozzles waste nozzles and MIX paddle in the same way Wear medical rubber gloves to keep skin from direct contact with patients samples Give special consideration to keep skin and mucous membrane from contact with reagents to prevent operator from possible infection Wear medical rubber gloves goggles etc to keep skin and mucous membrane from contact with reagents Read the statements of virtues that came with reagents prior to their use The contact with the wastes such as used reaction cells and solutions may cause infection Handle th
67. 3HIM 6 CHEMIX 800 SERVICE MANUAL uw gew swa Tef EN e BE mwaj nif eee 5 owxmaHo axn CMT SNIdOO 19 QNIHIM see ASSY TE __________ 24000 ALT STVOIGHN O1d VISYSNVAL 090 Avg YOOV 2900 0262 ASSY 0313 HLOLON 39NIHAS lt JS 5 oo ONIdOO 9 ONIMIM ASSV ONIdOOT 9 ASSV JONIMAS LdcH 1 o __ 9 565 J e o VY o O ELECTRICAL DESCRIPTION sem 2 3 08 eat 008 XIAN3HO NO 9351 TLO0OH VANNA 411 STVOIGSN OId VISVSNVUL 3009 UF EN POOSSVI ASSY 0313 B 31970 gt 9 AN 4 93871 5 INNON 5411 318 9 88065 0 d 18VO 0 DI SSY 82d 15604 v00SSV4 ASSY 93913 MIIA LNOYS SNIdOOT 9 ONIMIM ASSV Z 9 LMINMILS CHEMIX 800 SERVICE MANUAL 2 T 50 20 28 1 00010 T ASSY UH 007ES aod SARC OV lt 3S hS JX J ktE 6 X lt 1 8
68. 4 Loosen the 3 allen screws located at the centre ofthe RCT Light beam should fall on the centre of the cuvette table adjust its position such that the light beam falls mark on the calibration plate on the centre black coloured mark on the calibration plate Tighten the mounting screws NOTE Take care that the centring is not disturbed while tightening the RCT cuvette table mounting screws Gently put back the cuvette in its position and fit the laundry back in place Ref CMX VER 05 05 05 Page No 5 19 Installation Installation CHEMIX 800 SERVICE MANUAL VERIFY PROPER LAUNDRY ALIGNMENT ACTION Initialise the system through the Service Check menu Disconnect the CRU up down motor connector Gently slide the Laundry vertical shaft pillar downwards into the cuvettes To centre the laundry assembly loosen the four allen mounting screws on which the laundry vertical shaft pillar is mounted If required you can also center the laundry assembly by adjusting the position by the four allen screws on which the entire laundry assembly is mounted on the analyser casting To adjust the circular angle of the laundry assembly locate the small allen screw that is embedded inside the laundry vertical shaft pillar top end To center the individual laundry probes in their respective cuvettes loosen the white delrin screw caps located at the top of the probes Verify that the cuvette drier and suction probes touch the bo
69. AGENT 1 amp 2 SYRINGE 500 ul TEFLON REAGENT 1 amp 2 SYRINGE 500 ul ASSY Na ELECTRODE K ELECTRODE CI ELECTRODE N SIS lt lt lt lt Ref CMX VER 05 05 05 Page No 12 16 PREVENTIVE MAINTENANCE DESCRIPTION 3 Months 6 Months 9 Months 12 Months REF ELECTRODE y y ISE BOTTLE WITH TUBE ASSY ISE PUMP CASSETTE Note quantity required 2 DI WATER FILTER f necessary Ref CMX VER 05 05 05 Page No 12 17 ERROR CODES LIST ERROR CODES LisT Assembly Error Error Message Trouble shooting Tips Code Stirrer 1 1 The connecters up down motor Stirrerl up down error during initialization upopto sensor out put has to be checked and verified A2 The connecters rotational motor home Stirrerl rotational error Na durin initialization direction opto sensor out put has to be checked and verified A3 The connecters up down motor Stirrerl up down error den upopto sensor out put has to be checked and verified A4 The connecters rotational motor home Stirrerl rotational error NES dumped direction opto sensor out put has to be 5 checked and verified Stirrer 2 The connecters up down motor Stirrer2 up down error during initialization upopto sensor out put has to be checked and verified B2 The connecters rotational motor home Stirrer
70. AMPLE OUTER gt SAMPLE TO CUVETTE The sample arm will move over Sample cup number 1 go down till it senses the liquid The syringe plunger moves down aspirating sample from the cup the arm then moves to the dispense cuvette position cuvette number 50 goes down into the cuvette till it senses liquid Stops and then move to the drain position where the contents of the probe is discarded The analyser does this multiple times till the STOP button is clicked the sample cup is empty or an error has occurred Ref CMX VER 05 05 05 Page No 5 22 INSTALLATION VERIFY REAGENT 2 ARM ALINGMENT NOTE The Reagent 1 arm is aligned with the RCT in the offset position NOTE The Reagent 1 arm alignment is done with respect to cuvette No 52 only and only a verification is done at the other positions ACTION REMARKS OBSERVATIONS Initialise the system through the Service Check menu To rotate the RCT tray to the offset position select SERVICE gt 8 REACTION TRAY gt REACTION TRAYSNITIALISE gt OFFSET gt Place a large 50 ml reagent bottle filled with tap water in position number 1 on the reagent tray use only tap water as it has ions for conduction Do not use deionised or distilled water Now go to SERVICE CHECK gt REAGENT 1 ARM RR 1 Select INITIALISE gt REAGENT OUTER gt REAGENT Verify that the Reagent probe dispense CUVETTE needle is at the centre of cuvette number The Reagenti probes moves over t
71. Check compression plate spring and seal b Ensure that all sensors and o rings are in place a Use Cleaning procedure lt CLEN gt for module b Disassemble module and clean or replace sensor with plugged flow path Replace bubble detector 4 Waste pump is malfunctioning Replace Waste Pump Air in Cal B and Air in Cal A 1 Cal and Cal A are segmented with air a Sensors are not properly compressed Check compression plate spring and seal b Ensure that all sensors and o ring are in place 2 Fibrin or salt is plugging the sensor flow path a Use Cleaning procedure lt CLEN gt for module b Disassemble module and clean or replace sensor with plugged flow path 3 Bubble detector is malfunctioning Replace bubble detector 4 Waste pump is malfunctioning Replace Waste Pump Ref CMX VER 05 05 05 Page 14 12 ISE MODULE Symptom Problem Correction Air in Cal B 1 Insufficient Cal B pipetted into module sample port a Host instrument must deliver 70 ul Increase dispense volume b Operator must place sufficient sample in sample cup to account for all test programmed 2 Sample not positioned properly a Pump not connected properly b Pump tubing obstructed or tubing length is excessive Air in Cal A no Chae Share 1 Cal A bottle is empty Replace Cal A Bottle with a new one purge and recalibrate reported for
72. DUCTION amp SPECIFICATIONS 1 1 INTRODUCTION 1 2 FEATURES 1 3 TECHNICAL SPECIFICATIONS 1 4 COMPUTER SPECIFICATIONS AND SET UP 1 5 BARCODE SPECIFICATIONS 2 PRINCIPLE OF ANALYSIS 2 1 MEASUREMENT AND PHOTOMETRY 2 2 SEQUENCE OF OPERATION 3 FUNCTIONAL DESCRIPTION 3 1 INSTRUMENT AND ACCESSORIES LAYOUT 3 2 SERVICE MENU SOFTWARE LAYOUT AND FUNCTION PREINSTALLATION CHECK 4 1 DIMENSIONS 4 2 ELECTRICAL REQUIREMENTS 4 3 SITE REQUIREMENT 4 4 FLOOR REQUIREMENTS 4 5 800 WOODEN CARTOON INSTALLATION 5 1 INSPECTION AND ACCESSORIES CHECKLIST 5 2 UNPACKING THE ANALYSER 53 INSTALLING THE ANALYSER 5 4 PREPARING THE ANALYSER CONNECTING EXTERNAL ACCESSORIES AND PERIPHERAL DEVICES 5 5 COMPUTER SETTINGS 5 6 SOFTWARE INSTALLATION 5 7 POWERING UP THE ANALYSER 5 8 VERIFYING PROPER MECHANICAL FUNCTIONS 5 9 VERIFYING PROPER HYDRAULICS FUNCTIONS 5 10 TEMPERATURE VERIFICATION PROCEDURE 5 11 PHOTOMETER VERIFICATION PROCEDURE 5 12 BCR Alignment Procedure 5 13 ANALYTICAL CHECK PROCEDURE 6 RELOCATION 6 1 TOOLS AND MATERIALS REQUIRED FOR PACKING THE ANALYSER 6 2 UNISTALLING AND DECONTAMINATING THE SYSTEM 6 3 PACKING THE ANALYSER 6 4 CERTIFICATE OF DECONTAMINATION Ref CMX VER 05 05 05 Contents page 1 CHEMIX 800 SERVICE MANUAL 7 ELECTRONICS CIRCUIT DESCRIPTION amp VERIFICATION PROCEDURE 7 1 REGULATOR PCB ELS52014 R0 7 2 ISOLATION BOARD ELS22030 R0 7 3 PCB ELS220
73. Drive PCB ELS32003 RO This PCB is used to drive the 110V AC valves The board drives five such valves The board accepts logic signal from the FPGA to turn ON OFF the valves The flow of the logic input signals is from the Interface board to Base 1 to AC Drive board The flow of the output signals is from AC Drive board to valves 7 18 WGPT PCB WGPTO3 This PCB is used to sense the levels of liquid in various cans provided with the machine The PCB is located inside the LOADCELL platform If the levels of the liquid is beyond the set limit the indicator led s mounted on the rear panel of the machine start flashing and a buzzer beeps The PCB also provides a logic signal to indicate the liquid level limits crossover This signal flows from the WGPT board to 9 pin d type connector on the rear panel to baseboard2 to interface board The loadcell platform is connected to the machine using a d type connector Ref CMX VER 05 05 05 Page 7 4 ELECTRICAL DESCRIPTION 8 Electrical description CHEMIX 800 WiRING BLOCK DIAGRAM WDS5001 WDS5034 WDS5003 WDS5004 WDS5005 WDS5006 WDS5007 WDS5008 WDS5009 WDS50010 WDS50011 WDS50012 WDS50013 WDS50014 WDS50015 WDS50016 WDS50017 WDS50018 WDS50019 WDS50020 WDS50021 WDS50022 WDS50023 WDS50036 WDS50025 WDS50035 WDS50027 WDS50028 WDS50029 WDS50030 WDS50031 WDS50032 WDS50033 WDS50037
74. E MANUAL CERTIFICATE DECONTAMINATION WHOMSOEVER IT MAY CONCERN THIS ANALYZER ALONG WITH ITS RELATED ACCESSORIES HAS BEEN INSPECTED AND DECONTAMINATED IN ACCORDANCE TO THE STIPULATED PROCEDURES LISTED OUT IN THE SERVICE MANUAL UNDER CHAPTER 6 2 UNINSTALLING AND DECONTAMINATING THE SYSTEM AND IN ACCORDANCE WITH LOCAL AND STATE LAWS INSTRUMENT MODEL SERIAL NUMBER DISTRIBUTORS NAME DISTRIBUTORS ADDRESS Relocation CITY COUNTRY CUSTOMERS NAME CUSTOMERS ADDRESS CITY COUNTRY PROCEDURES CARRIED OUT BY SIGNATURE DATE Ref CMX VER 05 05 05 Page No 6 8 ELECTRONIC CIRCUIT DESCRIPTION 7 7 Electronic Circuit Description This section deals with the electronic circuits and their functions it gives an overview regarding the general aspect of the PCB its location flow of the signals It provides the complete reference for the service personnel for diagnosis The section consists of the following 7 1 7 2 7 3 7 4 7 5 7 6 7 7 7 8 7 9 7 10 7 11 7 12 7 13 7 14 7 15 7 16 7 17 REGULATOR PCB ELS52014 R0 ISOLATION BOARD ELS22030 R0 OPTO PCB ELS22006 R0 PHOTOMETER ELS52013 R0 LSH PCB ELS52009 R1 LSS PCB ELS52010 R2 BACKPLANE 1 ELS52005 R1 BACKPLANE 2 ELS52014 R1 INTERFACE PCB ELS32002 R2 BASE BOARD 1 ELS52015 R0 BASE BOARD 2 ELS52008 R1 STIRRER PCB ELS32006 R1 RCT ELS52004 R0 MOTOR DRIVE ELS52002 R0 DC DRIVE ELS32004
75. EAGENT 1 amp REAGENT 2 PROBES 12 CHECK AND REPLACE IF NECESSARY THE STIRRER PADDLES 13 REPLACE THE LAUNDRY PROBES 14 REPLACE THE LAUNDRY TUBINGS 15 CLEAN THE SAMPLE TRANSPORT 16 CLEAN THE REAGENT TRANSPORT 17 CHECK AND REPLACE IF NECESSARY THE SAMPLE REAGENT 1 AND REAGENT 2 SYRINGE 18 CLEAN THE ANALYSER FANS 19 CLEAN THE BAR CODE READER 20 REPLACE THE LAMP 21 REPLACE THE ALL ISE ELECTRODES amp PERFORM A ISE CLEAN AND RINSE CYCLE 22 CHECK AND REPLACE IF NECESSARY THE ISE PUMP CASSETTES 23 CLEAN THE ANALYSER INTERNAL SURFACE FREE OF DUST 24 PERFORM AN AUTO SPAN CHECK AND NOTE DOWN THE GAIN VALUES FOR 340 WAVELENGTH 25 PERFORM A CUVETTE RINSE 26 PERFORM A PRECISION CHECK AND NOTE DOWN THE CV FOR AN END POINT AND KINETIC TEST Ref CMX VER 05 05 05 Page No 12 10 PREVENTIVE MAINTENANCE 27 CARRY OUT SITE VERIFICATION FOR TEMPERATURE LINE VOLTAGE ELECTRICAL GROUND VENTILATION EXTERNAL INTERFERENCES ROOM LIGHTING AND LABORATORY CLEANLINESS PRACTICE AS DESCRIBED IN CHAPTER 16 1 SERVICING A CUSTOMER SITE 28 MAKE A DETAILED ENTRY IN THE ERROR LOG BOCK OF THE MAINTENANCE CARRIED OUT AND SITE VERIFICATIONS Ref CMX VER 05 05 05 Page No 12 11 Preventive Maintenance PREVENTIVE MAINTENANCE 12 3 USER DAILY amp WEEKLY MAINTENANCE LOG Name of
76. Hypochloride Bleach and then flush it multiple times with deionised water Dry and adequately pack the probes with sufficient protection in separate boxes Ref CMX VER 05 05 05 Page No 6 4 RELOCATION Figure showing the Sample Reagent1 Reagent2 Probe tip immersed in sodium Hypochloride solution NOTE When replacing the cuvettes back into their slots make sure that you grip them by their sides and top end Never let the fingers or any sharp object come in contact with the optical area 18 Rotate the Sample Reagent and Reagent 2 arm and lower them into the Sample and reagent tray wells 19 To decontaminate the Stirrer paddles soak a tissue paper in 5 096 dilution of a 5 25 Sodium Hypochloride Bleach and wrap it around the probes upper end then gently slide the tissue paper down towards the tip and out of the probe repeat this cycle numerous times until you are satisfied that the probe is thoroughly cleaned Make sure that this cleaning procedure is done only in one direction that is from top to down and not in the reverse Repeate the same procedure with deinoised water 20 Rotate the Stirrer arm and lower them into the Sample and reagent tray wells The Cuvette rinsing unit suction probes comes directly in contact with human sera BIOHAZARD and is highly Biohazardus please take the necessary precaution to protect yourself when carrying out this procedure Unscrew the metal thumbscrew Located above the cuv
77. INITIALISE STANDARD OUTER gt DOWN Verify that the dispense needle is at the centre of the standard outer cup number S1 Select INITIALISE STANDARD INNER gt DOWN Verify that the dispense needle is at the centre of the standard inner cup number B1 Select NITIALISE x SAMPLE OUTER gt SAMPLE TO Verify that the dispense needle is at the CUVETTE gt CUVETTE TO DRAIN centre of the SPT drain Ref CMX VER 05 05 05 Page No 5 21 Installation Installation CHEMIX 800 SERVICE MANUAL Select INITIALISE gt SAMPLE OUTER gt SAMPLE TO Verify that the mean distance between the CUVETTE gt CUVETTE TO DRAIN gt DRAIN TO TROUGH dispense needle and sensor needle is at the centre of the SPT trough Select INITIALISE SAMPLE OUTER gt SAMPLE TO ISE Verify that the dispense needle is at the centre of the ISE sample port To align the probe to the ISE sample port loosen the four allen screws of the ISE assembly and move the entire ISE assembly in the direction required once properly positioned tighten the four allen screws Select INITIALISE TROUGH TO DILUTION CUVETTE Verify that the dispense probe is at the centre of the Dilution Cuvette number 42 Select INITIALISE DILUTION CUVETTE TO CUVETTE Verify that the probe is at the centre of both the cuvettes number 42 and 50 VERIFYING PROPER SAMPLE ARM FUNCTION Initialise the system trough the service Check menu Select SERVICE CHECK SAMPLE ARM gt INITIALISE gt LINK gt TROUGH TO S
78. ITE Voltages present in the CHEMIX 800 can produce severe electrical shocks Place the Analyser and the computer in the OFF 0 position and disconnect all line chords before attempting any maintenance procedure WARNING To prevent contaminating yourself and others treat all human sera as potentially BIOHAZARD Biohazards Follow the laboratory s safety protocol for cleaning and decontaminating the Analyser and surrounding work surface Do not perform any maintenance procedure other than those described in this CAUTION manual Electrostatic sensitive components present on the PC boards in the CHEMIX 800 require you to ground yourself even when the Analyser is in the OFF 0 position otherwise damage to the Analyser electro sensitive components and PC boards can occur CAUTION VERIFYING PROPER ROOM TEMPERATURE Measure the room temperature at different corners of the Laboratory the reccomended temperature is 15 to 30 degrees celcus There should not be a variations of more than 5 degrees in Room temperature per hour VERIFYING LINE VOLTAGE With the help of a Voltmeter Measure the following AC Voltages to the instrument Test points Expected voltages Phase and Neutral 220 Volts Phase and Ground 220 Volts Neutral and Ground Not more than 3 Volts VERIFYING PROPER GROUNDING Place the Analyser and the computer in the OFF 0 position and disconnect all line NOTE chords With the help of a Ohm meter measure the con
79. NS VS ATI 21 09 5 96 62 3215 02 DMV HOWS 9 cO en GL4 291 950SSMI Dad G4 Nid 281 2722 3215 07 i gt 1005 ON ELECTRICAL DESCRIPTION ee Mm ea 3Wwos eweez ___ lt BNOLLO3NNOO ONIH Y 220005 NANNAN STYVOIISM OIH VIS SNVAL 21111111 3000 CHEMIX 800 SERVICE MANUAL sin L1 088 ______ Nossuas 6006 ZL000r 1vann n ALT STVOIGHN OId M38AnN 3009 9T0SSAM ON TIHMNVHIN 54 15 AS 06 05 95 56 321 0 38 5 3LON SISSVHO 9 0b 1715 81 HIA IHA NSIO N ESOSSMO ON 0 7 vEOSSMO 1 2 T00SSTM ON een Nid Za lt lt ELECTRICAL DESCRIPTION ovossam sin Lae ava TL0006 IVANNAN GLI STVOICAN O0IA VISYSNVIL 3000 79065 BLOSSAM Lond Low LL LOU YILSINUIHL BLOSSOM 940 ASSY LONG LOY P 22717 EOOSSAMON SANS V8L AZL OL TEOSSMI ON 2 J9 ON sr
80. NTENANCE LOG 12 6 SPARES REPLACEMENT SCHEDULE 13 ERROR CODES LIST 14 ISE MODULE 14 1 ISE MODULE MEASUREMENT FEATURES AND BENEFITS 14 2 TECHNICAL SPECIFICATIONS 14 3 ISE MEASUREMENT THEORY 14 4 ELECTRODES 14 5 MAINTENANCE SCHEDULE 14 6 ERROR CODES LIST 14 7 REAGENT CONSUMPTION 14 8 ACCEPTABLE CALIBRATION RANGES 14 9 TROUBLESHOOTING PROCEDURES 14 10 ISE MODULE MECHANICAL ASSEMBLY 15 ACCESSORIES SPARES AND CONSUMABLES SHORT LIST 15 1 ESSENTIAL SPARES SUGGESTED BE STOCKED THE CUSTOMER 15 2 STANDARD ACCESSORIES SUPPLIED WITH THE ANALYZER Ref CMX VER 05 05 05 Contents page 3 CHEMIX 800 SERVICE MANUAL SAFETY SUMMARY The CHEMIX 800 is designed to operate safely When you operate the system in a safe environment in accordance with the guidelines and procedures stipulated in this manual and there are no known operating hazards When a special condition exists you will see a WARNING BIO HAZARDOUS CAUTION or NOTE symbol in this service manual The following information explains these symbols Explaining Warnings WARNING INDICATES A HAZARDOUS CONDITION THAT IS ASSOCIATED WITH USING THE ANALYSER BIO HAZARD INDICATES A CONDITION INVOLVING INFECTIOUS BIOLOGICAL AGENTS CAUTION INDICATES AN ACTION OR CONDITION THAT CAN LEAD TO EQUIPMENT DAMAGE OR LOSS OF DATA NOTE INDICATES AN IMPORTANT GENERAL RULE THAT IS ASSOCIATED WITH OPERATING THE ANALYSER AN ACTION OR CONDITION THAT CAN LEAD TO EQUIPMENT DAMAGE OR L
81. OD range ODO 2 5 e Light path calculated as 10 mm Resolution 0 0001 OD Light source Pre aligned Halogen lamp 12V 20W Life expectancy 1 000 hours Grating Concave grating Detector Silicon photo diode array Cell blank correction Corrected by water blank measured after cuvette washing Minimum reaction liquid volume 180 ul Ref VER 05 05 05 Page No 1 11 Introduction amp Specifications Introduction amp Specifications CHEMIX 800 SERVICE MANUAL Data processing Item Description Calibration K Factor Linear one point two point and multipoint Logit log Spline curve Exponential Polynomial second third and fourth order Multipoint curves up to 10 points point correction to multi point calibration line is provided Quality Within day as well as day to day X and X R control diagram control Mean SD are calculated for each chemistry Repeat run Execution by repeat run list or auto execution Auto execution according to abnormal marking or range over Reduced increased volume repeat run also possible Monitor Reaction curve graphical display function e Calibration curve graphical display Operation status watching by run monitor Cuvette blank monitor Calculation Correlation correction factor Y aX b between Calculation by the formula defined by user items o Up to 40 calculated ite
82. OSS OF DATA Ref CMX VER 05 05 05 Contents page 4 CHEMIX 800 SERVICE MANUAL Abbreviations used ASP SAMPLE ROTATING ASSEMBLY ASSY COMPLETE ASSEMBLY BAR BARCODE CRU CUVETTE RINSING UNIT DET DETERGENT STIR STIRRER Same as mixing unit MIX MIXER Same as stirring unit PCB Pcb PRINTED CIRCUIT BOARD R T ROTATE R1PP REAGENT 1 PIPPETING PUMP DILUTOR SYRINGE ASSY REAGENT 1 PIPPETING ASSEMBLY R2PP REAGENT 2 PIPPETING PUMP DILUTOR SYRINGE ASSY R2PT REAGENT 2 PIPPETING ASSEMBLY RCT REACTION TRAY RGT REAGENT TRAY RSLS REAGENT LEVEL SENSING SMPS SWITCH MODE POWER SUPPLY SPP SAMPLE PIPPETING PUMP DILUTOR SYRINGE ASSY SPT SAMPLE PIPPETING ASSEMBLY BRPS BARCODE POWER SUPPLY SW SWITCH U D UP DOWN V VOLTS V AC AC Voltage V de V DC Voltage DC PM Preventive Maintenance LED Light Emitting Diode w r t With Respective To with reference to Conn Connector FRC Flat Ribbon Cable Flat cable used for carrying data Ltr Ltrs Litres Tx TX Transformer Ma Mille amps PM Preventive Maintenance WGPT WEIGH BRIDGE PLATFORM Level sensing platform ISO Pcb ISOLATOR board FTB1 TERM INAL BLOCK FUSE Fuse Box TB TERMINAL BLOCK Connector OPTO OPTICAL Ref CMX VER 05 05 05 Contents page 5 INTRODUCTION amp SPECIFICATIONS l Introduction amp Specific
83. OTOMETER ELS52013 RO It provides voltage signals proportional to the light intensity for 13 wavelengths It is located inside a special box beside the RCT The flow of signals is from photometer board to Interface board via a special shielded cable 7 5 7 6 Liquid Level Sensing PCB s The LLS circuit is divided into 2 PCBs LSH ELS52009 R1 LSS ELS52010 R2 for convenience of mounting on the arm The LLS liquid level sensing circuit is used to detect the level of sample and reagents in the cuvettes cups Also it is supposed to give a signal Vod if the cuvette cup is empty In this case the probe will hit the cuvette bottom 7 7 BACKPLANE 1 PCB ELS52005 R1 The backplanel PCB accommodates five stepper motor drive cards It accepts signals from FPGA and drives the stepper motors 7 8 BACKPLANE 2 PCB ELS52014 R1 The backplane2 accommodates one DC drive card and one stirrer DC motor driver card t accepts signals from FPGA and drives the Valves Pumps stirrer DC motors provide 5V power to the LLS cards provide pressure sensor digital signal to the micro controller 7 9 INTERFACE PCB ELS32002 R2 Its functions can be summarized as follows e generate signals to drive the Valves Pumps stirrer DC motors Ref CMX VER 05 05 05 No 7 2 ELECTRONIC CIRCUIT DESCRIPTION sense opto isolator signals read photometer card voltages perform calculations Serial communication with RGT contr
84. OW ADJUSTMENT PROCEDURE 11 3 1 2 8 SAMPLE PROBE DISPENSE VERIFICATION Ref CMX VER 05 05 05 Page No 11 Hydraulics Adjustments amp Verification Hydraulics Adjustments amp Verification CHEMIX 800 SERVICE MANUAL 11 1 PRESSURE TANK ADJUSTMENT PROCEDURE ANALYSER HYDRAULICS PRESSURE REGULATOR PRESSURE TANK PUMP DRAIN OBSERVATIONS To Adjust pressure locate the pressure regulator Pressure gauge should be between 0 8 and 0 9 bar located just above the pressure tank with the help of a spanner unlock the locking nut With the help of an allen key rotate and adjust the pressure regulator Go to the Service check menu click on the pump Observe a small fountain of water in R1PT R2PT SPT and trough valves button Switch ON the CKD amp Stirrer troughs valves for R2PT SPT 8 STIRR one after the other Switch ON all the switches together and keep the Verify that the water flow should be smooth and there hydraulic assembly ON for some time should be no leakages and that the pressure gauge does not fluctuate Ref CMX VER 05 05 05 11 2 HYDRAULIC ADJUSTMENTS AND VERIFICATION PROCEDURE 112 LAUNDRY FLOW ADJUSTMENT PROCEDURE Aspirate Drier P Probe 1 Probe2 Probe Probe4 Probe5 robe6 Probe Figure 14 1 ADJUSTMENT PROCEDURE Go to service check menu and initiate a
85. Pay attention to inclination vibration shock including shock during transportation etc 4 the analyzer is positioned at customer end then adjust the leveling bolts such that the castor wheels are just lifted above the ground level Use level indicator for ensuring the machine is leveled properly 5 Do not install the analyzer at the place adjacent to the storage room of chemicals or the place where any gas is likely to be generated 6 Pay attention to frequency voltage and permissible current or power consumption 7 Make sure that the analyzer is correctly and well grounded 8 Connect the analyzer to the operational PC using accompanying LAN cable When the other cable is used this may cause the analyzer to suffer from disturbing noise exert an adverse effect on its surroundings or get incorrect measurement results 3 The following cautions should be born in mind and exercised before the analyzer is operated Check the power supply frequency voltage and current capacity power consumption Ensure that the analyzer is correctly and well grounded Ensure that all the necessary electrical cables are correctly connected Check that the contact conditions of switches and indicators are appropriate and that the analyzer is ready to be activated correctly NOTICES FOR USE 1 CHEMIX 800 Extreme care must be taken not to result in misdiagnosis or pose any danger to the analyzer or human body when the analy
86. R1 ISPS PCB ELS22019 R0 AC Drive Board ELS32003 RO Electronic Circuit 7 18 WGPT BOARD WGPT03 Ref CMX VER 05 05 05 Page 7 1 description Electronic Circuit description CHEMIX 800 SERVICE MANUAL 7 1 REGULATOR ELS52014 RO This accepts 15 0 15 from the transformerl and delivers 15VDC 250mA power to the Photometer board It consists of two separate power supply section for 15V and 15V The power supply cable goes from the regulator PCB to Baseboard1 to Interface to Photometer PCB The PCB is located on the L plate behind the cardframes 7 2 ISOLATION PCB ELS22030 RO This PCB is used for isolating the TxD RxD gnd signals between chemix and PC It consists of two sections of communication ports One is the PC side and other is the equipment side The board uses RJ45 connectors for its two ports Two 5V power supply sections have been built on this PCB The TxD RxD signals are isolated using the opto isolators in the circuit It is located on the L plate behind the cardframes 7 3 PCB ELS22006 RO It provides a logic high signal when the opto isolator is interrupted cut by a mechanical assembly motion provides a logic low signal when the opto isolator is uninterrupted not cut The signal is interpreted by FPGA s The flow of signals is from opto PCBs to Baseboard1 PCB to Interface PCB These PCBs are distributed all over the machine 7 4 PH
87. SCRIBED IN CHAPTER 16 1 SERVICING A CUSTOMER SITE Ref CMX VER 05 05 05 Page No 12 6 PREVENTIVE MAINTENANCE 27 MAKE A DETAILED ENTRY IN THE ERROR LOG BOCK OF THE MAINTENANCE CARRIED OUT AND AND SITE VERIFICATIONS Ref CMX VER 05 05 05 Page No 12 7 CHEMIX 800 SERVICE MANUAL HALF YEARLY MAINTENANCE 1 CLEAN THE WASTE CAN CLEAN THE BIO HAZARDOUS WASTE CAN CLEAN AND FILL THE DEIONISED WATER CAN Bi CLEAN THE CLEANING SOLUTION CAN CLEAN THE LEVEL SENSING PLATFORM CHECK THE LEVELS OF CAL A SOLUTION REPLACE IF REQUIRED CLEAN THE ANALYSER EXTERNAL SURFACE CLEAN THE COMPUTER TROLLEY MONITOR KEYBOARD AND PRINTER EXTERNAL SURFACE CLEAN THE AREA AROUND THE ANALYSER DISARD ANY UNWANTED ITEM MAINTAIN PROPER ROOM CLEANLINESS 10 CLEAN THE SAMPLE REAGENT 1 amp REAGENT 2 PROBES 11 CLEAN THE Stirrer 1 and Stirrer 2 PADDLES 12 CLEAN THE LAUNDRY PROBES 13 REPLACE THE LAUNDRY TUBINGS 14 CLEAN THE SAMPLE TRANSPORT 15 CLEAN THE REAGENT TRANSPORT 16 CLEAN CHECK AND REPLACE IF NECESSARY THE SAMPLE REAGENT 1 AND REAGENT 2 SYRINGE PLUNGER TIP 17 CLEAN THE ANALYSER FANS 18 CLEAN THE BAR CODE READER 19 REPLACE THE LAMP 20 REPLACE THE ALL ISE ELECTRODES amp PERFORM A ISE CLEAN AND RINSE CYCLE 21 CHECK AND REPLACE THE ISE PUMP CASSETTES 22
88. SPT up down error during The connecters up down motor initialisation upopto sensor home opto sensor out put has to be checked and verified 72 rotational error The connecters rotational motor during initialization upopto sensor home opto sensor direction opto sensor out put has to be checked and verified 73 SPT Up Down Movement The connecters up down motor upopto sensor home opto sensor out put has to be checked and verified 74 The connecters rotational motor SPT Rotational Error upopto sensor home opto sensor during run direction opto sensor out put has to be checked and verified 75 The connecters VOD opto sensor SPT VOD Error placement of reagent bottles arm position in cuvette arm position in trough has to be checked and verified 76 Sample Absent The connecters LLS board has to be checked and verified ASP 81 ASP Rotational Error The connecters stop opto base opto during Initialization outputs has to be verified Consider the interlock effects while trouble shooting 82 ASP Rotational Error The connecters stop opto output has to during run be verified Consider the interlock Ref CMX VER 05 05 05 Page No 13 3 Error Codes List Error Codes List CHEMIX 800 SERVICE MANUAL Assembly Error Error Message Trouble shooting Tips Code effects while trouble shooting Sample Syringe 91 SPT syringe up down The connecters up down motor syring error during initialization op
89. SSV 13NVd Vad asva ELECTRICAL DESCRIPTION 025252525252525252524 e e 9 99 99 99 4 555552552525 ees e e e 9 9 9 poo Dl 5 e ia m CHEMIX 800 SERVICE MANUAL NOISIA3U 3NOZ A34 62055 woamn id __ ZL000r vannn 11111111 GIT SIVOIGHA OIH VISVSNVUL 3009 ASSV 0650V SHOSNIS LOY 12095 9 ASSV 2314 IHIH MOTT3A TIY 03430710S WO9L 7 SHIM DAd MOTTIA 9647 12055 ASSY 0313 7 beossva ASSY 9919 ee ile A mom v e wu ELECTRICAL DESCRIPTION 0 045 SUN 0 2 82 NO 21000 GIT SIVOITHN 0IA VISVSNVA ASSV 99 0140 X NAPS 3A33 1 MOVIE prozia 3009 0058V4 ASSY 72414 MIIA MOVE ONIHIM ASSY 19 145 FLOSSOM ONIHM FR Ei 51 2 2 pnm 00SSV4 ASSY 0414 LLOSSMO ASSV 37875 Iz IE FR 290 9 ONILYINSNI MIIA V dqadaWassv 5 ONISNOH 9 ONIMIM ASSV 1424 ld LM lds 5 S
90. Sample or Cal B 2 Tubing is disconnected Reconnect or replace tubing 3 Cal A pump is not working properly a Check electrical connections b Replace pump cassette c Replace motor 4 Tubing is plugged split or crimped Replace tubing Ref CMX VER 05 05 05 Page No 14 13 ISE Module ISE Module CHEMIX 800 SERVICE MANUAL 14 10 ISE MODULE MECHANICAL ASSEMBLY ISE ASSEMBLY XLAD 202 SOC VONT XLAD 201 Ref CMX VER 05 05 05 XLAD 203 Page No 14 14 ISE MODULE ISE COMPLETE ASSEMBLY ISE MODULE FSPIMOO1 hr M3x10 PH HD SCREW PW SW 4 NOS N N
91. Susmex TRANSASIA Service Manual Draft Version Clinical Chemistry Analyzer Model CHEMIX 800 CHEMIX 800 REVISION RECORD The latest edition supercedes any preceding ones If you have old editions discard them to avoid possible confusion REV DATE REVISION HIGHLIGHT 0 May 05 Published as Technical Information 2005 REVISION RECORD 2 CHEMIX 800 THIS PAGE IS INTENTIONALLY LEFT BLANK REVISION RECORD 2 CHEMIX 800 COPYRIGHT OF THIS MANUAL Copyright of this document belongs to TRANSASIA BIOMEDICALS LTD No part of this document may be reproduced transmitted transcribed stored in any retrieval system or translated into any language by any means electronic or mechanical including photocopying and recording for any purpose other than the purchaser s personal use without the express written permission of TRANSASIA BIOMEDICALS LTD TRADEMARKS COPYRIGHT OF THIS MANUAL 1 CHEMIX 800 THIS PAGE IS INTENTIONALLY LEFT BLANK TRADEMARKS COPYRIGHT OF THIS MANUAL 2 CHEMIX 800 FOREWORD This clinical chemistry analyzer consists of main analyzer including software and software on operational PC And the analyzer is used with operational PC and printer and can interact with the host computer With the inclusion of Barcode Readers for both Samples and Reagents the control of Samples and Reagents becomes fully automatic hence making the entire process of analysis au
92. TER SAVE TAKE A BACK UP OF ALL PATIENT REPORTS TURN OFF THE POWER TO THE MAIN ANALYSER UNIT BY TURNING OFF THE POWER SWITCH LOCATED ON THE SIDE OF THE ANALYSER ANALYSER TO BE KEPT IN THE STAND BY MODE Ref CMX VER 05 05 05 Page 12 4 Preventive Maintenance PREVENTIVE MAINTENANCE WEEKLY MAINTENANCE 1 CLEAN THE WASTE CAN 2 CLEAN THE BIO HAZARDOUS WASTE CAN 3 CLEAN AND FILL THE DEIONISED WATER CAN 4 CLEAN THE CLEANING SOLUTION CAN 5 CHECK THE LEVELS OF CAL A SOLUTION REPLACE IF REQUIRED 6 CLEAN THE ANALYSER EXTERNAL SURFACE 7 CLEAN THE COMPUTER TROLLEY MONITOR KEYBOARD AND PRINTER EXTERNAL SURFACE 8 CLEAN THE AREA AROUND THE ANALYSER DISARD ANY UNWANTED ITEM MAINTAIN PROPER ROOM CLEANLINESS 9 CLEAN THE SAMPLE REAGENT 1 amp REAGENT 2 PROBES 10 CLEAN THE STIRRER PADDLES 11 CLEAN THE LAUNDRY PROBES 12 CLEAN THE SAMPLE TRANSPORT 13 CLEAN THE REAGENT TRANSPORT 14 CLEAN THE SAMPLE REAGENT 1 AND REAGENT 2 SYRINGE 15 PERFORM AN AUTO SPAN CHECK AND NOTE DOWN THE GAIN VALUES FOR 340 WAVELENGTH 16 PERFORM A CUVETTE RINSE 17 PERFORM A PRECISION CHECK AND NOTE DOWN THE CV FOR AN END POINT AND KINETIC TEST Ref CMX VER 05 05 05 Page 12 5 CHEMIX 800 QUARTERLY SERVICE MANUAL MAINTENANCE 1 CLEAN THE WASTE CAN CLEAN THE BIO HAZARDOUS WASTE CAN CLEAN AND FILL THE
93. TROUGH R1PT trough Ref CMX VER 05 05 05 Page No 5 23 Installation Installation CHEMIX 800 SERVICE MANUAL VERIFYING PROPER REAGENT 1 ARM FUNCTION Initialise the system trough the service Check menu To rotate the RCT tray to the offset position select SERVICE CHECK gt CRU amp REACTION TRAY gt REACTION TRAY gt NITIALISE OFFSET Select SERVICE CHECK gt REAGENT 1 ARM gt INITIALISE gt LINK gt REAGENT INNER gt REAGENT CUVETTE The Reagent arm will move over Reagent bottle number 1 go down till it senses the liquid The syringe plunger moves down aspirating reagent from the bottle the arm then moves to the dispense cuvette position cuvette number 52 pauses and then moves to the drain position where the contents of the probe is discarded The analyser does this multiple times till the STOP button is clicked the reagent bottle is empty or an error has occurred Ref CMX VER 05 05 05 Page No 5 24 INSTALLATION VERIFY REAGENT 2 ARM ALINGMENT NOTE The Reagent 2 arm is aligned with the RCT in the reset position NOTE The Reagent 2 arm alignment is done with respect to cuvette No 39 only and only a verification is done at the other positions ACTION Place a large 50 ml reagent bottle filled with tap water in position number 1 and a small 20 ml reagent bottle filled with tap water in position number 4 on the reagent tray use only tap water as it has ions for conduction Do not use deionised
94. VOIGHN OId VISYSNYAL 3009 20 6999 X3 10A TIAMNVHN SANS VC 8 8 0015 6809SM2 LLOSSV3 ON ASSY T3SS3A 6S0SSM9 ON 5 SISVHO 9 0v 4445 vL SMV 96 56 3215 02 JHM HOW 9 amp 281 SORT SAIS OE ON lt N gt 100850 281 SSOSSMO ON 9HG ELECTRICAL DESCRIPTION NOISIA3U INOZ S UN e 3 008 d3sn ale fil SNOILOANNOO SANS V C A9 TL0007 IVANNN STVOITHN O0IE VISVSNVAHLL 3009 ASSY HILVIH 090SSMI ON DIA MOGNIM LOY 14809 Twos svin SANS E Nidzal ADE Nid 40014841 so FSOSSMO Gr ASSV H31V3H 108 3ZIS FL NHO T3A 3215 07 CHEMIX 800 SERVICE MANUAL i 008 0 0350 EY BNOILOANNOD SANS V S AZI SIVOIGHW OIS VISVSNVeLL FIOSSVA gEIEZ 3215 02 ANIM ASSY dWVIOL 6 088MO ON OHU N AZL SISVHO ASSV TIIMNVAIN SdI
95. ack stopper caps onto the Biohazards waste cleaning solution and Deionised water outlet nozzles and the white semi transparent big cap onto the waste outlet nozzle that is located on the rear of the analyzer 10 Turn off the power to the Analyser computer monitor and printer 11 Remove the Waste and Bio Hazardous waste cans and discard them in regulation with the local law DO NOT SHIP THEM BACK WITH THE ANALYSER 12 Turn off the power to the Analyser computer monitor and printer 13 Disconnect all external cables and peripheral devices Wipe the Trolley Monitor Computer and Keyboard external surface with a non abrasive cleaner or a use a soft lint free clot moistened with a 0 5 dilution of a 5 25 Sodium Hypochloride Bleach solution to clean and decontaminate the trolley computer monitor and printer external surface But before using it make sure that you test it on a small section of the trolley and Computer wait till it dries see the results only if you are satisfied that there is no damage or change of colour to plastic parts then proceed to clean the entire Computer and Trolley with this cleaning solution Make shure no solution falls or seeps into the Computer Monitor Printer or Keyboard 14 Adequately pack all the cables Power chord and peripheral devices into the accessories box Ref CMX VER 05 05 05 Page No 6 3 Relocation CHEMIX 800 SERVICE MANUAL NOTE Do not ship any a
96. and will reset the calibrated data to its default data Sample arm 7 8 9 Initialization This command will bring sample arm at home position trough position Up If SPT arm is down at trough position or in sample tray this command will bring R1 arm at up home position till the up opto doesn t cut Down this command can be used to check down movement of Sample arm First give lt initialize gt command then give lt To reagent inner or To Reagent outer command 4 then give Down command The Sample arm will go down until the bottom of the reagent bottle While going down if it senses liquid level in between it will stop at that level If liquid is not there in reagent bottle then it will go down will experience VOD at bottom and displays 75 Sample Arm VOD error 10 Link This command is used to set SP Arm Motion Cycle continuously for validation and service check test To execute initialized the arm first by clicking initialized button after complete initialization force link command by clicking link button once To terminate action use stop button provided on the left hand side corner of the screen Ref VER 05 05 05 Page No 3 11 Functional Description Functional Description CHEMIX 800 SERVICE MANUAL 11 RCT Home For sample arm alignment at cuvette side RCT should be at Home initialization position 12 Sample outer This command will first initializes Sample tray amp a
97. assembly The base assembly consists of the rotating shaft and bearing assembly alongwith the slipring assembly The Water jacket assembly is a stationary assembly meant for covering the rotating part of the rct i e the housing and the cuvette ringset assembly The cuvette ringset assembly consists of 72 slotted ring outer ring cuvette retaining spring and cuvette retaining plastic pieces alongwith the foil heater mounted at the bottom of the 72 slotted ring The cuvette ring set assembly also houses the three thermistor assemblies meant for monitoring the temperature of the RCT The terminals of the photometer lamp are mounted onto the water jacket assembly B Components of ASP assembly Component Function Operation Rotating Motor Stepper Motor Imparts rotary motion to the cuvette ring set assembly Home position sensor Opto interruptor For sensing the home position of the cuvette ringset assembly Rotation position sensor Opto Interruptor For sensing the rotation position of the cuvette ring set assembly Cuvettes not shown Reaction cuvettes 72 nos Slipring assembly To supply to the foil heater and to transport the sensing signals of the thermistors Thermistor assembly not shown meant for monitoring the temperature of the cuvette ring set assembly Foil heater not shown meant for heating the RCT table Water jacket assembly Meant for covering the cuvette ring set assembly
98. ata field then click on the SAVE ERRORS button select the location where you require the data to be stored and click the OK button 4 Remove and discard all Sample cups and Reagent bottles old and new DO NOT SHIP THEM BACK WITH THE ANALYSER 5 Remove the Cleaning solution and DI water cans along with their external associated tubing s and discard them in regulation with the local law DO NOT SHIP THEM BACK WITH THE ANALYSER 6 Drain the system as follows Click on the SERVICE CHECK button click on the CUVETTE RINSE button and perform an entire cuvette rinse repeat this cuvette rinse cycle multiple times till all the water from the Pressure Vessel and associated tubes have been drained out 7 drain the ISE system click on the SERVICE CHECK button click on the ISE UNIT button and perform a clean cycle followed by multiple PURGE cycles approximately 15 cycles Remove the Cal a bottle and discard its contents perform multiple PURGE cycles approximately 15 cycles Remove the electrodes dry them and pack them in their respective original boxes that were supplied with them Place the electrodes in the accessories box 8 Remove the Hydraulics side panel of the analyzer and locate the drain nut and tube place the drain tube into a shallow container and open the drain nut and allow the entire contents of the pressure vessel to drain out After completing the draining procedure DO NOT FORGET TO CLOSE THE DRAIN NUT 9 Put the Bl
99. ations This section consists of the following 1 1 INTRODUCTION 1 2 FEATURES 1 3 TECHNICAL SPECIFICATIONS 1 4 COMPUTER SPECIFICATIONS AND SET UP 1 5 BARCODE SPECIFICATIONS amp ALLIGNMENT PROCEDURE Ref VER 05 05 05 Page No 1 1 Introduction amp Specifications Introduction amp Specifications CHEMIX 800 SERVICE MANUAL 1 1 Introduction This manual imparts a technical understanding of SYSMEX TRANSASIA S fully automated CHEMIX 800 analyser It is meant to compliment the CHEMIX 800 operators Manual If the reader encounters areas that are not fully explained Please refer to the operator s manual This manual does not intend to teach troubleshooting skills It is designed to provide a competent service engineer trained on the CHEMIX 800 with the necessary information required to maintain the CHEMIX 800 analyser Certain sections of this manual are subject to change New revisions of these documents will be sent as Engineering change records Technical bulletins to all authorised distributors of CHEMIX 800 If you come across any discrepancies or required corrections your feed back on the same to us would be highly appreciated Optimum performance of the analyser is guaranteed only by the use of genuine Transasia supplied parts Transasia will not be responsible for failures associated with the use of unauthorised parts or unauthorised modifications carried out by the distributor or customer In
100. ations CHEMIX 800 SERVICE MANUAL The CHEMIX 800 bar code positive identification The bar coded reagents and sample identification minimises programming time Bar coded sample tubes provide positive sample identification and minimises risk of biological hazards The CHEMIX 800 optical system ensures reliability of results The CHEMIX 800 uses a high resolution flat field optically corrected diffraction grating to ensure high degree of photometric accuracy The user can select from 12 available wavelengths from 340 nm 800 nm to cover the entire clinical chemistry application range The long life quartz halogen light source and the photodiode array complete the photometric system of the CHEMIX 800 OTHER FEATURES OF CHEMIX 800 Unique soft start and stop of all mechanical assemblies ensures smooth operation and adds reliability Software routines provide the user with all functions to run the analyser The user friendly software that continuously provides and prompts the operator assistance The Sample R1 amp R2 probe vertical obstruction detection VOD system detects obstructions there by protecting the probes from potential damage Single probe liquid level detection by means of Capacitance sensing ensures accurate level detection and accurate alignment Ref VER 05 05 05 1 4 INTRODUCTION amp SPECIFICATIONS 1 2 Specifications General specifications Item Description Throug
101. ccessories that have been in contact with Bio Hazardous fluids Due to possible spillage the sample tray comes in contact with body fluids To prevent contaminating yourself and others treat all human sera as potentially Biohazards Take the necessary precautions to protect your self from contamination and personal injury 15 Lift and remove the Sample and reagent tray carousel with the help of a soft brush and a lint free clot moistened in a 0 5 96 dilution of a 5 25 96 Sodium hypo chloride bleach solution clean and decontaminate the Sample and reagent tray also remove all debris and spillage from the wells of the Sample and Heagent trays dry and pack them individually and appropriately into cardboard boxes ocation The Cuvettes comes directly in contact with human sera and is highly Biohazardus BIOHAZARD please take the necessary precaution to protect yourself when carrying out this procedure 16 Locate the thumb screws on top of the reaction tray unscrew and gently lift the reaction tray cover below the cover locate the three Allen screws unscrew and lift the reaction tray place it on a table Remove each individual cuvette from their slots making sure they do not get scratched place them in a bowl containing a warm laboratory detergent Recommended is a 296 solution of Extran Rinse the cuvettes thoroughly with DI water dry them and place them in their original boxes that were supplied with them Clean the empty R
102. ce it on the reagent tray cover the reagent tray with the reagent tray cover wait for about an hour till the temperature has stabilised Insert a sensitive thermal measuring device into the reagent bottle and measure the temperature Go to the SERVICE CHECK menu and click on the TEMPERATURE button and verify the temperature of the reagent tray displayed on the screen the temperature displayed should be approximately 12 to 15 degrees lower than the ambient room temperature The measured temperature and the displayed temperatures should approximately match REACTION TEMPERATURE VERIFICATION PROCEDURE Reaction tray temperature should be measured only after the analyser has reached thermal NOTE stability by having completed a warm up time of at least 30 minutes After having reached thermal stability introduce a thermistor into a cuvette no 34 filled with 180 of cold 7deg c DI water make sure that the measuring device is completely inserted into the liquid wait for about 5 minutes and note down the reading it should be 37 degrees 0 2 degrees Go to the SERVICE CHECK menu and click on the TEMPERATURE button and verify the temperature of the Reaction tray displayed on the screen the temperature displayed should match the value read using thermistor Ref CMX VER 05 05 05 Page No 5 33 Installation Installation CHEMIX 800 SERVICE MANUAL 5 11 PHOTOMETER VERIFICATION PROCEDURE Photometer check procedure should be carried out
103. control 60 types of control parameters maximum 3 types per test item Stand by 24 hours stand by is allowed when used 30 minute warm up time Safety mechanism Vertical obstruction detection Capacitance based liquid level sensing Noise level e Less than 65 dB Display 15 inch color display Standard keyboard Auxiliary storage medium 3 5 inch floppy disk System interface Analyzer PC RS 232C bi directional Optional Touch screen monitor Electrolyte measurement unit for Na A4 size DeskJet color printer Off line PC Host computer TCP IP bi directional Automatic water supply from an outside DI water unit Reagent bar code ID Ref VER 05 05 05 Page 1 6 INTRODUCTION amp SPECIFICATIONS Installation conditions Item Description Power source AC220 V 10 50 or AC 110 V 10 60 1 Hz consumption factory setting Power consumption 800 VA Drainage e Used sample concentrated waste solution and washed sample diluted waste are to be drained separately Ambient e 15 30 C temperature Variation during operation less than 2 C per hour Relative humidity 40 80 free from water dew formation Dimensions 890 x 760 D x 1140 mm Weight Approximately 150 kg Ref VER 05 05 05 Page No 1 7 Introduction amp Specifications I
104. cular reagent The reagent probe then moves up rotates and places its self over cuvette number 1 and partially moves down over the cuvette Reagent 2 syringe plunger then moves up and stops when it reaches the home position thereby dispensing its reagent contents into the cuvette The Reagent 2 probe then moves to the trough drain position where it rinses the probe internally by activating the R2PP CKD valve and washes the probe both internally and externally by activating both R2PT amp R2PP CKD valves of both the trough and Reagent 2 dilutor syringe Stirrer 1 The sample and the primary reagent dispensed into cuvettes are stirred by rotating the paddle 3 types of speed are available i e Low Medium and High The user selects the appropriate speed as per the chemistry reaction The paddle is washed in the STIRRER 1 trough with system water at 40 C and pressure of 0 8 1 2 bar Stirrer 2 The sample and the primary reagent dispensed into cuvettes are stirred by rotating the paddle 3 types of speed are available i e Low Medium and High The user selects the appropriate speed as per the chemistry reaction The paddle is washed in the STIRRER 2 trough with system water at 40 C and pressure of 0 8 1 2 bar Reporting The optical densities are measured for each test every time the RCT rotates and the cuvette passes the light path The cycle time for a complete rotation is 10 seconds that is every 10 seconds the optical densities are
105. cuvette Monitor the flow of cleaning solution from the rinse cycle cleaning solution can to the DET pump trough the tubing s to the first laundry probe and into the first cuvette To regulate the detergent flow remove the right side panel and locate the black coloured flow regulator on the top of the detergent pump Adjust it in order to enable the detergent flow into the first cuvette to fill up to of the total volume of the cuvette Verify that there is no spillage of detergent from any of the cuvettes Observe this carefully for multiple rinse cycles Ref CMX VER 05 05 05 11 3 Hydraulics Adjustments amp Verification Hydraulics Adjustments amp Verification CHEMIX 800 SERVICE MANUAL ACTION WATER FLOW ADJUSTMENT PROCEDURE Go to service check menu and initiate a cuvette rinse cycle OBSERVATION Monitor the flow of deionised water from the DI water can to the pump to the pressure vessel and trough the tubing s into the cuvettes under laundry probes 2 3 4 amp 5 also verify a proper drain from all the cuvette To regulate the deionised water flow open the rear panel ISE door locate the flow regulator this regulator is connected in line with the deionised water tubing to the laundry system Adjust it so that at the time of rinsing the deionised water flow into the second third fourth and fifth cuvette located under the second third fourth and fifth laundr
106. d stops when it reaches the home position thereby dispensing its contents into the cuvette The sample probe then moves to the trough drain position where it rinses the probe internally by activating the SPP CKD valve and washes the probe both internally and externally by activating both SPT amp SPP CKD valves of both the trough and sample dilutor syringe In the next rotation the reaction tray rotates to the offset position where the stirrer will perform a mixing cycle Once the Sample is added into the cuvette the reaction starts Whenever the RCT rotates by one turn all 72 cuvettes pass under the light beam and optical densities if all these 72 cuvettes are measured for the defined wavelengths Reagent 2 addition Reagent 2 if present is added in the 25 cycle Reagent 2 probe rinses itself both internally and externally by activating both the R2PT amp R2PP CKD valves of both the trough and Reagent 2 dilutor syringe The reagent tray then rotates and positions the requested reagent at the Reagent 2 pickup position The Reagent 2 probe then rotates and positions its self over the reagent bottle starts moving down the Reagent 2 probe liquid level sensing is now active it continues to move down until it senses the presence of reagent Once the presence of liquid is sensed it moves down a little further into the reagent and then stops The reagent 2 Syringe moves down and aspirates the defined volume of reagent for that parti
107. e Reagent 1 amp 2 syringe Clean the analyser fans Clean the bar code reader Replace all ISE electrodes Check and replace if necessary the the ISE pump cassette replace the lamp perform an auto span check Perform cuvette rinse check amp note cuvette blanks perform a precision check Take a back up of all necessary data Patient results Parameters Calibration data QC data Control data System switch amp Sequence Carry out a site verification for temperature line voltage electrical ground ventilation external interferences room lighting and laboratory cleanliness practice as described in chapter 16 1 SERVICING A CUSTOMER SITE Make a entry in the Customer error log book Ref CMX VER 05 05 05 Page No 12 15 CHEMIX 800 SERVICE MANUAL 12 6 SPARES REPLACEMENT SCHEDULE Name of the Customer Name of the Operator Service technician Month From to Model CHEMIX 800 Serial No DESCRIPTION 3 Months 6 Months 9 Months 12 Months SPT PROBE ASSY R1PT PROBE ASSY R2PT PROBE ASSY STIRRER PADDLES CUVETTE DRIER CHIP TEFLON LAUNDRY DISPENSE TUBINGS LAUNDRY ASPIRATION TUBINGS LAUNDRY PROBE ASSY PHOTOMETER LAMP ASSY lt lt lt lt lt lt lt lt lt SAMPLE SYRINGE PLUNGER WITH TEFLON 100 ul lt lt 444 lt SAMPLE SYRINGE ASSY 100 ul lt RE
108. e of the analyser verify that the system initialises and home all the assemblies Power on the computer system on the desktop menu screen double click on the CHEMIX 800 icon Verify that the analyser initialises its self and home all assemblies Please note after installing the CHEMIX software and you activate the software by double clicking on the CHEMIX Icon only the first time you are obligated to enter the username and password please enter the same username and password as mentioned on the CD cover of the application software Ref CMX VER 05 05 05 Page No 5 18 INSTALLATION 5 8 VERIFYING PROPER MECHANICAL FUNCTIONS VERIFY LIGHT BEAM ALIGNMENT ACTION REMARKS OBSERVATIONS Switch ON the machine and Initialise RCT assy through the Service Check menu Remove the CRU unit thumbscrew lift up the laundry unit and In the initialised or reset position the gently remove the cuvette which is the path of the light beam following are the positions of the cuvettes Insert the Light beam centring gauge Part No FSPS2723 Probe cuvette position 72 that is supplied in the accessories box in place of the cuvette Probe2 cuvette position 71 making sure it touches the wall of the cuvette housing on all Probe3 cuvette position 70 sides Probe4 cuvette position 69 Probe5 cuvette position 68 Probe6 cuvette position 67 Light path cuvette position 66 Suction probe cuvette position 65 Drier probe cuvette position 6
109. e photometric results are then transferred back to the Analyser PC where the results are processed stored and then reported The robotics consist of a Sample arm Reagent 1 arm Reagent 2 arm Stirrer 1 Stirrer 2 Cuvette Rinsing Unit Sample tray Reagent tray Reaction tray and three Dilutors one each for sample Reagent 1 amp 2 The sample tray consist of two Sample Disks one for loading routine and stat patient samples with a total of 50 positions and the other for loading the following 2 Blanks 8 Controls 2 ISE and 20 Calibrators Routine samples can be loaded as primary tubes or sample cups Both reagents and samples have a Barcode identification system Bar coded sample tubes provides positive sample identification and minimises risk of human related errors and biological hazards Some of the Salient technical features of the system are listed below 8 stage triple probe cuvette Wash Station On board Biohazard and regular waste management 2 Teflon coated mixer stirrers 2 Reagent capability 72 position hard glass moulded cuvettes 60 position bar coded reagent carousel capable of accommodating 20ml and 70 ml Reagent bottles On board reagent cooling is provided by a solid state state of the art Peltier cooling system 7 50 positions bar coded sample tray with a detachable Standard tray for standard amp Controls 8 Throughput of up to 600 tests hour 360 test hour photometric and 240 test hour ISE 9 Primary tube samplin
110. eaction tray and incubation well with the help of a soft brush and lint free clot soaked in a diluted solution of 15 dilution of a 5 2596 sodium Hypo chloride dried them and fit the reaction tray with the cover back in place 17 Remove the Sample Reagent 1 and Reagent 2 Probes and place them into a beaker or test tube filled with a mild Sodium hypochloride or extran solution the level of the solution should be such that only the lower two centimeters of the probe is in contact with the solution no liquid at any time should come in contact with the probe sensor wires embedded withen the probe upper half if it does happen please rinse the probe in deionised water and thoroughly dry it before refitting The sample probe system comprises of two metal cocentric probes that are used for liquid level sensing order to clean this probe from the outside soak a tissue paper in 5 096 dilution of a 5 2596 Sodium Hypochloride Bleach and wrap it around the probes upper end then gently slide the tissue paper down towards the tip and out of the probe repeat this cycle numerous times until you are satisfied that the probe is thoroughly cleaned Make sure that this cleaning procedure is done only in one direction that is from top to down and not in the reverse Repeate the same procedure with deinoised water in order to clean the sample probe internally gently with the help of a syringe flush the probe first with a 5 0 dilution of a 5 25 Sodium
111. elocation of the Analyzer by anyone other than a service representative will not be covered under warranty Besides the various decontamination procedures listed out under chapter 6 2 UNINSTALLING AND DECONTAMINATING THE SYSTEM Other procedures listed out by local State or National law authorities should also be carried out all bio hazardous items must also be disposed off in accordance with these reaulations NOTE M Voltages present in the CHEMIX 800 can produce severe electrical shocks Place the analyzer and the computer in the OFF 0 position and disconnect all line chords before attempting any maintenance procedure WARNING Pack the Analyzer carefully otherwise you can damage accurately adjusted CAUTION optical and electronic assemblies Any Analyser Analyser spares being shipped back that has had Bio hazardous material run on it must be decontaminated and the decontamination certificate that has been included under chapter 6 4 CERTIFICATE OF DECONTAMINATION must be filled duly signed and attached with the shipping documents NOTE Various Bio hazardous contaminated parts exists in a analyser that has been used proper precaution should be taken to protect one self when relocating the analyser as well as the decontamination procedures should be properly carried out as per the recommended procedures listed under chapter 6 2 UNINSTALLING AND DECONTAMINATING THE SYSTEM BIOHAZARD The Sample pr
112. em with gloved hands without exception Follow the national or local laws and rules when they are thrown out There are two kinds of liquid wastes drained from this analyzer i e high and low concentrated wastes The access to the conductive parts within the analyzer may cause serious electric shock When removing parts make sure to shut off the power supply Leave any maintenance and repair of electrical parts inside the equipment to a qualified service personnel Never leave reagent bottles on the working table upper surface inside the analyzer Careless handling of reagent bottles may cause tumble and leak Do not make a modification to the analyzer gt Exchange the halogen lamp for a new one after a lapse of 30 minutes since the power switch of the analyzer is turned off to avoid danger of burns SAFTY WARNINGS 4 HEMIX NOTICES FOR USE SAFETY AND PREVENTION AGAINST DANGER The user is requested to read this instruction before he uses the analyzer for the first time and becomes acquainted with how to operate the analyzer 1 Only qualified personnel should use the analyzer 2 The following precautions should be taken when the analyzer is installed 1 Keep the analyzer out of the rain and any other water splash 2 Avoid areas that are adversely affected by atmospheric pressure temperature humidity ventilation sunlight dust air containing salt or sulfur etc 3
113. ep Dead volume User programmable dead volumes for reagents samples and standards Mixing Reagent identification Type Immersion mixing by rotating mixers Two mixers 3 variable mixing speeds Mixing positions The 1 position Right after sample dispense into the first reagent The 24 position 1 reagent sample R2 Position ID Reagent bar code ID Residual volume information Calculated by count down system as well as measured by capacitance type level sensor and displayed on screen Reagent positions Total 60 positions which can be used for reagent 1 2 Reagent protection Reagent cover protection from evaporation dust and direct light Carry over actions Extra Detergent Reagent Wash given for Carry Over Pairs Ref VER 05 05 05 Page 1 9 Introduction amp Specifications Introduction amp Specifications CHEMIX 800 SERVICE MANUAL Reaction unit Item Description Type e Turn table Reaction tray Rotating tray Number of reaction cuvettes 72 Temperature control Turn table direct heating by foil heaters Reaction e 37 0 2 temperature Cuvettes Reusable Number of reaction cuvettes 72 Dimensions 5 x 4 9 mm Optical path length 5 mm factor to be fed for 10 mm Material Hard glass Volume 710 ul Reaction liquid volume 550 ul maximum 180 ul minimum Reaction liquid mixing Type Immersion mixin
114. erify that there is no spillage of detergent from any of the cuvettes Observe this carefully for multiple rinse cycles ACTION OBSERVATION DEIONISED WATER FLOW VERIFICATION PROCEDURE Go to service check menu and initiate a cuvette rinse Monitor the flow of deionised water from the DI water cycle can to the pump to the pressure vessel and trough the tubing s into the cuvettes under laundry probes 2 3 4 amp 5 also verify a proper drain from all the cuvette To regulate the deionised water flow open the rear panel ISE door locate the flow regulator this regulator is connected in line with the deionised water tubing to the laundry system Adjust it so that at the time of rinsing the deionised water flow into the second third fourth and fifth cuvette located under the second third fourth and fifth laundry probe fills to 34 the total volume of the cuvette Verify that there is no spillage of deionised water from any of the cuvettes Observe this carefully for multiple rinse cycles VERIFY PROPER PROBE DISPENSE SAMPLE From the SERVICE CHECK menu select SAMPLE ARM click on INITIALIZE click on SAMPLE OUTER click on SAMPLE TO CUVETTE click on CUVETTE TO DRAIN CLICK on the GO BACK button From the SERVICE CHECK menu select SYRINGES then select SAMPLE SYRINGE click on INITIALIZE and click on the VALVE ON Check and confirm that a clear uninterrupted straight jet of water emerges from the probe that is
115. es to the computer settings are required Minimum Computer Processor Intel Pentium IV 1 7 Ghz NOTE this is the Requirements MINIMUM LEVEL recommended Memory 512 MB SD RAM Hard Disk 40 GB Floppy drive 3 5 CD ROM 52 X Monitor 15 inches Colour Keyboard Standard Mouse Standard Interface 2 X RS 232 ports Operating system Windows XP Service Pack 2 Ref CMX VER 05 05 05 Page No 5 13 Installation Installation CHEMIX 800 SERVICE MANUAL COMPUTER CMOS SETUP STANDARD CMOS FEATURES 1 Enter Date and Time 2 IDE Primary Master Press Enter the next screen will appear Select AUTO for both IDE Primary Master and IDE Access Mode 3 IDE Primary Slave Select NONE 4 IDE Secondary Master Press Enter the next screen will appear Select AUTO for both IDE Secondary Master and IDE Access Mode 5 DRIVE A Select 1 44MB 3 5 6 Drive B Select None 7 Flopy3 mode support Select Disabled 8 Video Select EGA VGA 9 Halt On Select KEYBOARD ADVANCED BIOS FEATURES 1 First Boot Device Select HDD 2 Second Boot Device Select CD ROM 3 Third Boot Device Select FDD 4 Bootother Device Select No 5 Swap Floppy Disc Select Disabled 6 Security Options Select Setup ADVANCED CHIPSET FEATURES 1 CPU clock speed Select x8 INTEGRATED PERIPHERALS 1 USB Controller Select Enabled 2 USB Keyboard support Select BIOS 3 USB Mouse support Select OS 4 AC97 A
116. ette Reagent 1 syringe plunger then moves up and stops when it reaches the home position thereby dispensing its reagent contents into the cuvette The Reagent 1 probe then moves to the trough drain position where it rinses the probe internally by activating the R1PP CKD valve and washes the probe both internally and externally by activating both RIPT R1PP CKD valves of both the trough and Reagent 1 dilutor syringe Sample addition The reaction tray rotates and places cuvette 1 at the sample probe dispense position Sample probe rinses its self both internally and externally by activating both the SPT amp SPP CKD valves of both the trough and Sample dilutor syringe The sample tray then rotates and positions the requested sample number at the sample pickup position The sample probe then rotates and positions its self over the sample cup starts moving down the sample probe liquid level sensing is now active it continues to move down until it senses the presence of liquid Once the presence of liquid is sensed it moves down further into the sample by another few millimeters and then stops The sample Syringe moves down and aspirates the defined volume of sample for that particular sample The sample probe then moves up rotates and places its self over cuvette number 1 Ref CHX VER 05 05 05 Page 2 7 Principle of Analysis Principle of Analysis CHEMIX 800 SERVICE MANUAL Sample syringe plunger then moves up an
117. ette rinsing unit plate lift the cuvette rinsing unit upwards And place it in a shallow tray Clean individual probes with the help of a lint free tissue moistened with a 0 596 dilution of a 5 25 Sodium hypo chloride rinse thoroughly with deionised water and dry When refitting the Cuvette rinsing unit make sure that the suction probes go M directly in the center of the cuvette slot and they do not touch the walls Refit the Cuvette rinsing unit and place a buffer packing material between the top plate of the rinsing unit and the top plate of the analyzer Ref CMX VER 05 05 05 Page No 6 5 Relocation Relocation CHEMIX 800 SERVICE MANUAL 6 3 PACKING THE ANALYZER B Do not ship any accessories the main analyzer box all accessories should be shipped separately in the accessories box CAUTION Pack the Analyzer carefully otherwise you can damage accurately adjusted optical and electronic assemblies 13 Wrap the plastic protective sheet around the entire analyzer Lift or slide the analyzer onto the wooden pallet by holding the base plate of the analyzer CAUTION Sm eat lifting the analyzer by its side panels can damage the analyzer Place the base pallet just besides the right side hydraulics side of the analyzer NOTE B Make sure the pallet is positioned correctly that is the analyzer will finally rest on the pallet with the front of the analyzer facing the side marked front on the pallet Gently lift the
118. g by rotating mixers Two mixers 3 variable mixing speeds Mixing positions o The 1 position Right after sample dispense into the first reagent o The 2 position 1 reagent sample R2 Cuvette washing Type By the automatic washing system The reaction waste is aspirated out then cuvette is washed by washing solution and repeatedly by DI water finally residual liquid is removed Number of washing operation steps 9 steps o Reaction waste removal 1 step o Washing 6 steps o Residual liquid removal 2 steps Number of washing solution application o Detergent solution 1 o lon exchange water 5 Washing solution container o Detergent 10 liters Capacity Reaction waste is collected into two waste cans concentrated waste and diluted waste by pumps In built cuvette overflow protection Ref VER 05 05 05 Page No 1 10 INTRODUCTION amp SPECIFICATIONS Optical absorption measurement unit Item Description Type Multiple wavelength diffraction spectrophotometer Photometric system Multi wavelength direct measurement of light after penetration into reaction cuvette transmitted light Wavelength 12 Wavelengths 340 405 450 480 505 546 570 600 660 7700 750 and 800nm Wavelength per e or two wavelength chemistry Measurement interval Total 63 points Interval depends on the cycle time o Every 10 seconds for 10 second cycle time
119. g with barcode identification 10 Permanent hard glass moulded cuvettes 11 Economical 180 per test reagent consumption 12 Low de ionised water requirement of apprx 13 5 Lts hour 13 Twelve wavelength diffraction grating 9 OU coc The Chemix 800 Sample tray flexibility and convenience The specially designed Twin layered sample disk of CHEMIX 800 provides unmatched flexibility and convenience the routine rack has positions to accommodate up to 50 routine samples The standard rack has 20 standards 2 blanks and 8 controls and 2 ISE positions The sample tray can accommodates standard tube sizes of 5 7 or 10 ml amp sample cups The Chemix 800 reagent tray offers a wide choice of on board bottles The CHEMIX 800 offers up to 60 single reagent bottles can be loaded at any time All reagents are refrigerated to ensure extended stability The wide choice of on board reagents eliminates the need for sample splitting and cuts down the turn around time of reporting The Chemix 800 economy quick returns without compromise The Chemix 800 uses permanent hard glass cuvettes thereby eliminating recurring costs of disposable cuvettes 180ul of reagent per test maximises the number of tests per rack Deionised water requirement of just 13 5 litres hour saves pre installation costs of an on line de ioniser plant Ref VER 05 05 05 No 1 Introduction amp Specifications Introduction amp Specific
120. gh position In the same fashion SPT pipettes the Samples Standards Controls placed in the Sample Tray and dispenses in the cuvette or into the ISE receptacle as the case may be Then the Arm positions to the Trough position and the SPT Probe is cleaned with warm DI water internally and externally at the trough position B Components of SPT R1PT and R2PT Arm Assemblies Component Function Operation Up Dn Motor Stepper Motor Imparts Up Dn motion to the probe Rotation Motor Stepper Motor Imparts Rotation motion to the probe Probe Aspirates Dispenses Sample Reagent Respective Syringe facilitates Aspiration Dispensing VOD Sensor Opto Interruptor Vertical Obstruction Detection Sensor for Probe to prevent damage to probe Trough Position Sensor Opto Interruptor For Sensing the Home Position i e the Trough in the Rotational direction Rotation Position Opto Interruptor For sensing the position of probe in Rotational Sensor direction Up Dn Position sensor Opto Interruptor For sensing the Home position of the pipette Top Position in the Vertical Direction GE Eis 12 22 2 01 0 Dq Galww tesi IM MM 0 1 mw O O OO SCREWS MR ER 1 SOE SET SCREWS RAT PONT 1 Til VOD sensor Rotation Motor Trough Position Sensor Rotational Position
121. h or alike with rubbing alcohol before the analyzer is used At this time do not forget to put medical rubber gloves or alike on Pay attention to prevent bare skins of hands or arms from being touched by or pricked with the nozzle tip Pay attention to the storage area a Keep the analyzer out of the rain and any other water splash b Avoid areas that are adversely affected by atmospheric pressure temperature humidity ventilation sunlight dust and air containing salt sulfur etc C Pay attention to inclination vibration shock including shock during transportation etc NOTICES FOR USE 2 CHEMIX 800 d Avoid areas adjacent to the storage room of chemicals or areas that are likely to generate gasses Avoid areas that are likely to be subject to inclination vibration and shock Organize and store parts and cords associated with the analyzer after they have been cleaned Keep the analyzer clean not to cause any inconvenience to the next use 7 n the event of trouble please do not fiddle with the analyzer In case of any trouble always ensure that the analyzer is handled by authorized service personnel 8 Maintenance and checks lt is important for the analyzer and its associated parts to be periodically checked Ensure that the analyzer operates normally and correctly when it is reused after being kept unused for some time NOTICES FOR USE 3 CHEMIX 800 SERVICE MANUAL Contents 1 INTRO
122. hput 360 tests hour 600 tests hour with ISE for a cycle time of 10 seconds System type e Discrete open automated random access patient prioritized 1 2 Reagent system Sample Serum Urine Others CSF Plasma etc Measurement principle Latex Turbidimetric Immunoassay Turbidimetric Immunoassay Colorimetry Rate End Point Ion Selective Electrodes optional Applicable analytes Photometric assays o Enzyme lipid protein sugar nitrides inorganic substances complements and others Turbidimetric assays o IgG IgA IgM RF ASO Transferrin and others Test method e Absolute measurement e Relative measurement ISE optional On board tests 60 test items maximum 63 test items with ISE Programmable parameters 96 photometric tests 40 calculation items Serum indices Optional 3 ISE tests Assay modes 1 Point 2 Point Rate A Rate B ISE optional Sample volume 2 70 ul adjustable in 0 2 ul step Reaction volume e 180 11 550 ul Reaction temperature 37 C Temperature stability 0 2 C Serum information Degree of Lipemia Icterus and Hemolysis can be measured and printed during Run Reaction time Ref VER 05 05 05 Depends on the designated cycle time and number of reagents used For step assay using 610 seconds 10 minutes 10 seconds for a cycle
123. hydraulics side of the analyzer as it is the lighter side and slide the wooden pallet below the side castors of the analyzer when doing this a foot should be placed on the one or slide of the pallet to prevent it from lifting gently slide the analyzer onto the wooden pallet and position it rotate the foot rests downwards in order to enable the analyzer to rest on the foot rest only and the castors are in mid air make sure that all four foot rests are adjusted to about the same height Carefully slide in Z brackets one at a time making sure that they fit into the groove provided on the footrest bolt down the Z brackets onto the wooden pallet as shown in figure 6 1 The instrument must be shipped with the Castors in mid air the Z bracket and the CAUTION footrest should support the entire weight of the instrument Cautiously fit the Z bracket to prevent any personal injury Fit the side panels of the wooden box and make sure that the following markings are clearly indicated on the wooden box Indication as to which side is the top and which is the bottom of the analyzer Fragile indication Do not tumble Do not stack on top this box Protect from sunlight and rain Precession instrument Copy of the certificate of decontamination Ref CMX VER 05 05 05 Page No 6 6 RELOCATION Side Panel 8 2 2 o 2 bracket Figure 6 1 Page No 6 7 Ref CMX VER 05 05 05 CHEMIX 800 SERVIC
124. igh reliability of results Maintenance free electrodes 6 months or 10 000 samples warranty Cost effective cost per test Disposable reference electrode no addition or filling solution required Minimum down time Ref CMX VER 05 05 05 Page No 14 2 ISE MODULE 14 2 TECHNICAL SPECIFICATIONS Sample Serum Plasma or Urine Urine requires dilution Sample size 60 ul 3 channels serum 160 ul diluted urine Reproducibility Maximum precision within run Typical carry over 96 serum Serum Na CV 1 5 100 160mmol L lt 0 5 K CV lt 2 3 00 600mmol L 1 5 96 2 80 120mmol L lt 1 0 96 Analysis time Serum 30 seconds including one point calibration Urine 60 including one point calibration Throughput Serum 120 samples per hour Urine 60 samples per hour Power 12V DC 0 6A Module Size Height 100 mm X 102 mm Width 91 mm Depth Reagents Calibrant A Calibrant B Cleaning Solution Urine Diluent Maximum Environmental Temperature 38 Degrees Centigrade Ref CMX VER 05 05 05 Page No 14 3 ISE Module ISE Module CHEMIX 800 SERVICE MANUAL 14 3 ISE MEASUREMENT THEORY The Electrolyte Measurement System measures Sodium Potassium and Chloride in biological fluids using ion selective electrode technology A diagram of the electrode measurement system is shown in figure 2 3 The flow trough sodium electrode uses selective membrane tubing
125. ing environmental and electrical suggestions to ensure the accuracy and precision of the analyzer NOTE This will also ensure a high level of operator and technical service personal working comfort and safety ENVIROMENTAL REQUIREMENTS VERIFYING PROPER ROOM TEMPERATURE Measure the room temperature at different corners of the Laboratory the reccomended temperature is 20 to 26 degrees celcius non condensing There should not be a variations of more than 5 degrees in Room temperature per hour VERIFYING PROPER VENTILATION Make sure there is at least 0 25 meters of space between the wall and the instrument on all three sides to enable proper ventilation There should not be any Stationary items or other objects in the vinicity that hinder proper access to the analyser There should be no direct air from the airconditioning system on to the Analyser VERIFYING DUST FREE ENVIROMENT Verify and ensure a dust free enviroment to the analyser this is a small but very important concideration when installing the analyser EXTERNAL INTERFERENCES Heavy duty electrical devices like Air conditioners refrigerator s ovens centrifuges etc should not be operated on the same electrical lines as the Analyzer or in the close vicinity of the analyzer The room should be free of vibrations from heavy duty devices like Centrifuges and Compressors The room should be free from strong magnetic fields caused by other medical equipment like CT Scans
126. ize Reagent tray disturbs it s home position amp rotates again to achieve the home position 2 60 Steps Reagent tray will take one complete rotation 3 1 Pulse Reagent tray will rotate for the one short clock pulse This can be used to check opto alignment of the tray 4 Link Reagent tray will rotate continuously If there is any problem in RGT opto setting then rotation will stop 5 Step Regent tray will rotate for one reagent position 6 Regent Barcode scan This command is used to scan all 60 barcode tubes Ref VER 05 05 05 Page No 3 13 Functional Description PREINSTALLATION 4 Preinstallation This section deals with the pre installation requirements for the CHEMIX 800 biochemistry analyser It lists the following 4 1 ANALYSER DIMENSIONS 4 2 ELECTRICAL REQUIREMENTS 4 3 SITE REQUIREMENT 4 4 FLOOR REQUIREMENTS 4 5 CHEMIX 800 WOODEN CARTON DIMENSIONS amp WEIGHTS Ref CMX VER 05 05 05 Page No 4 1 Preinstallation Preinstallation CHEMIX 800 SERVICE MANUAL 4 1 Analyzer Dimensions Note All dimensions are in mm TRANSASIA CHEMIX 800 FRONT VIEW CHEMIX 800 RIGHT VIEW Ref CMX VER 05 05 05 Page No 4 2 PREINSTALLATION 4 2 ELECTRICAL REQUIREMENT NOTE Failure to properly ground the CHEMIX 800 bypasses important safety features and may result in an electrical hazard A proper grounding is highly essential for safety and proper fu
127. lick Stop Stop el Next Delete Verify that the gains indicators show green and that none of them should show red Also the gain values displayed in the Gain Box for a 340 nm Wavelength should be between 70 to 125 Click on the STOP button click on the MANUAL SPAN SET button click on the START button then select individual detector wavelengths by clicking on them and note down the gain values The displayed gain values in the Gain box for 505 to 660 nm Wavelength should be between 70 to 240 Go to MAINTENANCE CUVETTE RINSE and perform a Cuvette rinse cycle Check and verify proper cuvette blank readings for all wavelengths in PREVIOUS DATA CUVETTE BLANK Ref CMX VER 05 05 05 Page No 5 34 INSTALLATION 5 12 BCR Alignment Procedure Reagent BCR 1 2 3 Mount the L shaped BCR clamp on the base Fix the clamp holder screw Arrange the BCR such that the distance between the BCR surface plane and the centre of the outer reagent bottle should not be less than 28 75 mm as well the distance between the centre of the inner bottle to the surface plane of the BCR should not be greater than 53 75 mm Place the inner bottles run the barcode scan and adjust the beam angle by small rotational variations so that the beam will fall on the BC as shown in the fig Place the outer bottles run the barcode scan and adjust the beam angle by small rotational variations so that the beam will fall on the BC as show
128. lign Sample position 1 for Sample arm calibration 13 Sample inner Before giving this command sample tray should be initialize by giving Sample outer command amp then give this command This command can be used for sample arm calibration at inner position 14 Default calibration This command will reset the calibrated data to its default data PC Communication This command will check the communication between PC amp Analyzer Select the communication port 1 2 or 3 4 amp click on check communication If communication is OK then pc will display communication with instrument OK If communication is not OK then pc displays Instrument not responding If this happens then check the continuity of communication wire or check whether RCT has been initialized or not Syringes In this there are 3 syringes on screen Select any one of them All the following commands are available for that particular Syringe 1 Valve on 2 Valve off Syringe up Syringe down Initialize 2 4 5 5 amp R2pt syringe have fixed steps to go down However for R1 syringe down movement we can change the steps from combo box Stirrers 1 2 Initialization During initialization stirrer performs rotation as well as up down movement Down for this action RCT should be at offset condition 4 it should be steady First give RCT Offset command then give lt Rotate to cuvette 1 or Rotate to cuvette
129. ls at the base board connecters connector connections and verify for proper functionality R1 Arm 11 Arm up down The connecters up down motor Error during initialization upopto sensor home opto sensor out put has to be checked and verified 12 Arm Rotational The connecters rotational motor Error during initialisation upopto sensor home opto sensor direction opto sensor out put has to be checked and verified 13 RIPT Arm Up Down The connecters up down motor Emor during run upopto sensor home opto sensor out put has to be checked and verified 14 The connecters rotational motor Arm Rotational upopto sensor home opto sensor Error during run direction opto sensor out put has to be checked and verified 15 The connecters VOD opto sensor Arm VOD Error P prisagent honey position in cuvette arm position in trough has to be checked and verified 16 The connecters LLS board has to be Reagent RI checked and verified RGT 21 RGT Rotational Error The connecters stop opto base opto During Initialization outputs has to be verified Consider the interlock effects while trouble shooting 22 The connecters stop opto output has to RGT Rotational Error be verified Consider the interlock effects while trouble shooting R1 Syringe 31 R1 syringe up down error The connecters up down motor syring during initialization opto sensor out put has to be checked and verified 32 Risveusetndown
130. m trough ORFL CKD VALVE After a water dispense cycle is completed by the laundry dispense probes the WATER CKD valve is shut The ORFL CKD valve is then enabled for a moment this action sucks and empties the remaining water contents from withen the laundry dispense probes there by preventing drippage from the dispense probes SPP R1PP amp R2PP VALVE Enables Disables the flow of deinosed water from from the pressure vessel to the Sample Reagent 1and Reagent 2 probes Pressure Reducer Regulator To regulate and mentain a steady water pressure in the tank vessel KNF Water Suction pump To pump De ionized water from the water can to the pressure vessel tank KNF detergent pump To pump detergent solution into the first laundry probe The pump comprise of an inbuilt regulator KNF Bio hazardous waste pump To suck the waste out from the firom the first laundry probe Double head waste Suction pump To suck the waste out from the firom the 2 3 4 5 6 amp 7 laundry probes And to suck out the contents from the ORFL CKD Valve a _ TROUGH UNITS 5 0 END USE 4 0 PRESSURE 10 d CONTROL 2 J 442 b ELEMENTS E T Itl RI TR 491 im TR PULSATION DAMPER G e Seal funis 4 4 5 SYR VLV 4 682 sve viv 3 5 Qr 354 Blohazardous MOVERS
131. matrix printer Continuous stationary printer System interface Analyzer RS 232C bi directional Ref VER 05 05 05 Page 1 14 INTRODUCTION amp SPECIFICATIONS 1 5 Barcode Specifications Specifications Type of Sample Codes read by the analyser NOTE Sample Bar Code Minimum 6 digits amp Maximum 10 digits in length User defined 2 5 Interleaved Code 39 Code 128 NW7 1 Scan Resolution 0 25mm Minimum width of the thin line 2 Paper requirement Non Glossy Non smudgy 3 Label sticking Refer to the following drawings FSPXL170 FSXPL169 FSPS2857 FSXPL140 and FSXPL139 4 Print Quality Clear thin line No smearing or smudging Ref VER 05 05 05 Page No 1 15 Introduction amp Specifications PRINCIPAL OF ANALYSIS 2 Principle of Analysis This section consists of the following 2 1 MEASUREMENT AND PHOTOMETRY 2 2 SEQUENCE OF OPERATION Ref CHX VER 05 05 05 Page No 2 1 Analysis CHEMIX 800 SERVICE MANUAL 2 1 MEASUREMENTS AND PHOTOMETRY Principle of Analysis The CHEMIX 800 analyzer is an automated clinical biochemistry analyser based on the principle of photometry it measures light transmittance at various wavelengths White light as we see it is actually composed of several colors This becomes evident when we pass a beam of white light trough a prism If the light emerging from
132. ms can be programmed o Each calculation item can include up to 3 chemistries Recalculation of results possible after modification in Calibration Parameters or Test Parameters Data storage e Test results 1 000 000 with back up capacity Reaction curve 9999 tests Report list Report generation Patient wise Test wise Date wise Location wise format Abnormal result wise Doctor name wise Lists Abnormal values list Pending run list Repeat run list Backup Backup of following data is possible Assay parameters Calibration data Results QC data System parameters Mechanical data Probe Calibration and Dead Volume settings Special Reagent blank correction treatment Data check Reference range check by age sex sample type e Panic limit check Reaction linearity check Reaction mixture absorbance checks Antigen excess prozone check by reaction time course analysis method Alarms and Types of alarms Erroneous operation mechanical malfunction of notices analyzer data processor hardware error erroneous test results e Alarm level Notice temporary halt of analysis suspension of analysis system stop e Prompts on display alarms Diagnostic Mechanical movements and functional performance be checked checks through diagnostic menu Password e Password provided to reject an access to selected menus Ref VER 05 05 05 Page 1 12 INTRODUCTION amp
133. n in the fig Repeat procedure pt no 4 and 5 to get best possible alignment and barcode read NOTE 1 The accurate separation between the BCR surface and the bottle surface is specified in the Figures attached here with pg 36 to 38 2 Barcode label placement on Reagent bottles is specified in the figures attached here with pg 39 Ref CMX VER 05 05 05 Page No 5 35 Installation Ref VER 05 05 05 INSTALLATION BAR CODE SCANNER DIMN Ref CMX VER 05 05 05 Page No 5 37 Installation CHEMIX 800 SERVICE MANUAL BAR CODE SCANNER DIMN uonejje31su 150 DVI 311108 YI 01 YAS Page No 5 38 Ref CMX VER 05 05 05 INSTALLATION REALEN BAR LABLE UIMN Ref CMX VER 05 05 05 Page No 5 39 Installation Installation CHEMIX 800 SERVICE MANUAL Sample BCR Mount the L shaped BCR clamp on the base Fix the clamp holder screw Arrange the BCR such that the distance between the BCR surface plane and the centre of the outer reagent bottle should not be less than 28 75 mm as well the distance between the centre of the inner bottle to the surface plane of the BCR should not be greater than 53 75 mm 4 Place the inner Tubes run the barcode scan and adjust the beam angle by small rotational variations so that the beam will fall on the BC as shown in the fig 5 Place the outter Tubes run the barcode scan and adjust the beam angle by small rotational variations so
134. nctioning of the analyser VOLTAGE AND GROUND REQUIREMENTS Voltage amp frequency Single phase continuous stabilized AC 220 volts 10V 50Hz The CHEMIX 800 comes equipped with a three pin power cord The type of cord and plug depends on the source voltage for the system Grounding It is absolutely necessary that a perfect earthing must be provided at the power source with all applicable local requirement Only a certified grounded 3 pin power plug should be used Plug points Four 5 amp sockets must be available near the analyzer Four sockets are required one each for the analyser computer monitor and printer It is recommended that two extra sockets be provided near the analyzer for use by a measuring equipment or engineering tool if required while servicing Example Oscilloscope Soldering iron etc Heavy duty electrical devices like conditioners refrigerator s ovens etc should not be operated on the same electrical lines as the Analyzer Failure to properly ground the CHEMIX 800 bypasses important safety features and may result In permanent damage to the analyzer that may void the warranty it is absolutely necessary to ensure proper grounding Ref CMX VER 05 05 05 Page No 4 3 Preinstallation Preinstallation CHEMIX 800 SERVICE MANUAL 4 3 SITE REQUIREMENT The proper location is an important consideration a poor location can lead to malfunction of the analyzer Please follow the follow
135. nd the main vertical shaft is stationary Tighten the Phillips screw Place the sample tray back in position VERIFY REAGENT TRAY ALIGNMENT NOTE The Reagent tray is aligned with reference to Reagent bottle number1 and Reagent 1 arm Probe only The Y axis is aligned using the Reagent 1 arm alignment procedure The X axis is aligned using the Reagent Tray alignment procedure 4 Y axis X axis Reagent bottle No 1 ACTION REMARKS OBSERVATIONS Initialise the system through the Service Check menu Place a Large 50 ml Reagent bottle filled with tap water in Positions number 1 on the reagent tray As tap water has ions for conduction Do not use deionised or distilled water Select SERVICE CHECK REAGENT 1 ARM ALIGN RGT INNER button 1 Select SERVICE CHECK REAGENT 1 ARM INITIALISE gt REAGENT INNER DOWN The Reagent probes moves down until it senses the present of liquid in the BOTTLE No 1 and then stops Verify that the dispense needle is in the centre of the Reagent bottle 2 Select SERVICE CHECK gt INITIALISE gt Adjust the Reagent tray as follows Ref CMX VER 05 05 05 Page No 5 28 INSTALLATION 3 Lift and remove the Reagent tray locate the 3 Allen screw NOTE Take care that the centring is not on the centre shaft as shown in figure 9 1 disturbed while tightening the Allen screws 4 Slightly loosen the three Allen screws and slowly rotate the top plate of the shaft in
136. nd will bring R1 arm at home position trough position 2 Up If Ri arm is down at trough position or in reagent tray this command will bring R1 arm at up home position till the up opto doesn t cut 3 Down this command be used to check down movement of R1 arm First give lt initialize gt command then give lt To reagent inner or To Reagent outer command 4 then give Down command The R1 arm will go down until the bottom of the reagent bottle While going down if it senses liquid level in between it will stop at that level If liquid is not there in reagent bottle then it will go down will experience VOD at bottom and displays 15 Riarm VOD error 4 Link This command is used to set R1 Arm Motion Cycle continuously for validation and service check test To execute initialized the arm first by clicking initialized button after complete initialization force link command by clicking link button once To terminate action use stop button provided on the left hand side corner of the screen 5 RCT offset For R1 arm alignment RCT should be at offset condition Ref VER 05 05 05 Page No 3 10 FUNCTIONAL DESCRIPTION This command will first initialize RCT tray then align RCT for R1 probe 6 Align R1 inner This command will first initializes RGT tray amp align reagent position 1 for R1 arm calibration 7 Default calibration This command will reset the calibrated data to its default data
137. nits STR1 meant for mixing R1 and Sample and STR2 meant for mixing R2 R1 and Sample will operate to perform the mixing operation When R2 is not programmed the STR2 mixing station will be idle To reduce the possibilities of contamination due to adherence to paddle the paddles are coated with hydrophobic materials e g Teflon After performing the mixing operation inside the cuvette the arm swings itself to the trough position wherein the warm DI water from the Pressure tank cleans the wetted surface of the Teflon coated paddle B omponents of STR1 and STR2 assemblies Component Function Operation Up Dn Motor Stepper Motor Imparts Up and Down motion to the Arm carrying the mixing paddle Rotation Motor Stepper Motor Imparts Rotation motion to the Arm carrying the mixing paddle Arm This element carries the mixing motor and the paddle Paddle Stirrer paddle Teflon Coated Up Sensor Opto interruptor For sensing the Home position of the Arm Trough Position Opto Interruptor For sensing the home position in the rotary direction At home position the stirrer paddle is over the trough position Rotation sensor Opto interruptor For sensing the position of the arm in the rotary direction NOTE 4 WHILE ASSEMBLING MAINTAIN BELT TENSION AS PER BELOW SPECFICATION BY ADJUSTING HEX NUT OF MOTOR ASSY BELT DEFLECTION 5 8 MAINTAIN CRITICAL DIMENSION lt gt Paddle Home Ro
138. nstallation Installation CHEMIX 800 SERVICE MANUAL 5 6 SOFTWARE INSTALLATION Prerequisites before CHEMIX installation Verify whether CHEMIX software is installed on the computer If yes then exit from the CHEMIX software application CHEMIX software application should not be open Take a back up of Program Files Chemix 800 Un installation Procedure Uninstall the existing CHEMIX software programme as follows Click on the MY COMPUTER icon Click on the CONTROL PANEL icon Double click on the ADD REMOVE Program icon Select by clicking the CHEMIX programme from list in the box Click on the ADD REMOVE button A message Are you sure that you want to remove CHEMIX version number amp all its components will be displayed Click on the YES button A message Remove all shared components will be displayed Click on the REMOVE ALL button Click on the OK button A message Un installation procedure completed will be displayed at the end Go to the DESK TOP screen and right click on the CHEMIX programme icon Click on DELETE Click on the YES button Delete all temp files before installation Installation process Insert the CHEMIX software CD into the CD drive Click START menu and select run option This will open a run panel Click browse and double click on CHEMIX version Select set up file and click open Click OK Welcome message will be displayed click OK Then click on the compute
139. ntroduction amp Specifications CHEMIX 800 SERVICE MANUAL Sampling unit Item Description Sample container Blood collection tube 10 ml 16 x 100 mm 7 ml 14 5 x 84 mm 5 ml 13 x 75 mm Adaptors will be provided for 5 and 7 ml tubes Cup Micro cup 0 5 ml Standard cup 2 ml Sample cups can be placed on the 7 ml tubes Sample placement Sample tray o Inner rim 25 routine patient samples with without barcode o Outer rim 25 routine patient samples with without barcode optional 5 positions for STAT Standard tray o Inner rim 2 blanks 8 controls amp 2 ISE solutions optional o Outer rim 20 positions each on Disc 1 and Disc 2 separately for standards STAT STAT samples Can be placed on the outer rim of Standard Tray only during patient Run or Sample Tray STAT samples are measured preferentially Interrupt permitted even during analysis Sampling Pipetting mode Pipetting system with plunger driven by stepper motor Sample volume 2 70 ul adjustable in 0 2 ul step Discharges set volume of sample into cuvette or the ISE module optional Sampling probe Micro pipette with level sensor Washing solution o Outside Preheated de ionized water o Inside Preheated de ionized water Equipped with vertical obstruction detection facility to prevent probe crash Sample dilution Dilution ratio 5 to 150 times A cuvette is used as dilution vessel Set amount of diluent is dis
140. nts and other additional accessories may be packed in another carton The representative is responsible for unpacking installing and initial setting up of the Analyser Remove the Nuts and Bolts that hold the side panels of the analyser and accessories box carefully remove each of the side panels Installation The instrument is shipped mounted on Z brackets the Z bracket and the CAUTION footrest support the entire weight of the instrument Cautiously open the bolts of the Z bracket to prevent any personal injury Unwrap the plastic protective sheet from the analyser The instrument is bolted down to the wooden pallet on four sides with the help of Z brackets remove these bolts carefully with the help of a spanner and carefully slide out the 2 brackets one at a time Rotate the footrests upwards in order to enable the analyser to rest on all four Castors Ref CMX VER 05 05 05 Page No 5 4 INSTALLATION CHEMIX 800 with base pallet and wood cartoon Ref CMX VER 05 05 05 CHEMIX 800 SERVICE MANUAL Nuts Top panel Analyser 1 c gt 2 Bracket Pallet Base Washers Chemix 800 with base pallet and wood cartoon Page No 5 6 Ref CMX VER 05 05 05 INSTALLATION Gently lift or slide the analyser out of the wooden pallet and place it on the floor Wheel the analyser to the installation site after position it rotate the foot rests downwards in orde
141. o cuvette number 52 52 NOTE the probe has two needles 1 Dispense needle that is hollow amp 2 Sensor needle NOTE Take care that the centring is not Verify that the hollow dispense needle is in the disturbed while tightening the Allen screw centre of the cuvette 2 Adjust the Reagent 1 probe as follows Lift and remove the probe plastic cover and locate the Allen Screw on the top end of the arm shaft Slightly loosen this Allen screw and rotate the top plate of the arm so as to position the dispense needle in the centre of the cuvette When doing this make sure that only the horizontal top plate rotates and the main vertical shaft is stationary Tighten the Allen screw Verify proper centring by repeating steps 1 to 2 Click ALIGN REAGENT INNER Button Verify that the probe is at the centre of the Select INITIALISE REAGENT INNER gt DOWN reagent bottle at position number 1 on the The Reagent 1 probe will move down into the reagent bottle reagent tray number1 until it senses liquid Click ALIGN REAGENT OUTTER Button Select INITIALISE gt REAGENT OUTTER gt DOWN The Reagent 1 probe will move down into the reagent bottle number4 until it senses liquid Select INITIALISE gt REAGENT INNER REAGENT Verify that the probe is at the centre of the CUVETTE gt CUVETTE TO DRAIN R1PT drain Select INITIALISE gt REAGENT INNER REAGENT TO Verify that the probe is at the centre of the CUVETTE gt CUVETTE TO DRAIN gt DRAIN TO
142. obe comes directly in contact with human sera and is highly BIOHAZARD biohazardus please take the necessary precaution to protect yourself when carrying out this procedure Ref CMX VER 05 05 05 Page No 6 1 Relocation Relocation CHEMIX 800 SERVICE MANUAL When carrying out this procedure sufficient precaution should be taken to BIOHAZARD protect your self from potential injury or infection To prevent contaminating yourself and others treat all human sera as potentially Biohazards 6 1 TOOLS AND MATERIALS REQUIRED FOR PACKING THE ANALYSER Base pallet with Z bracket and CHEMIX 800 standard wooden box Cardboard boxes for the accessories Protective Packing material like a bubble sheet or foam 2 brackets with nuts bolts and washers CHEMIX 800 standard tool kit Sodium hypo chloride Disposable paper tissues Gloves 5 25 SODIUM HYPO CHLORIDE BLEACH SOLUTION Four black stopper caps and a white semi transparent big cap required for the analyzer rear outlet nozzles Ref CMX VER 05 05 05 Page No 6 2 RELOCATION 6 2 UNINSTALLING AND DECONTAMINATING THE SYSTEM 1 From the Service Check menu perform a cuvette rinse cycle by clicking on the CUVETTE RINSE button and then clicking on the YES button 2 Take a printout or a backup on a floppy of the error log do this by clicking on the PREVIOUS DATA button then clicking on the RUN RECORD button then click on the all d
143. oller RCT controller Barcode scanners PC generate 3 3V power supply program the FPGA s and ST10 execute the program for running the machine 7 10 BASE BOARD 1 PCB ELS52015 RO It is a passive board linking the various signals between FPGA present on Interface board and backplanes opto pcbs LLS PSBs It contains signal connectors for motor drive board DC drive board AC drive board 7 11 BASE BOARD 2 PCB ELS52008 R1 It is a passive board linking the various signals between ST10 present on Interface board and barcode scanners Isolation card RCT card RGT controller RGT cover proximity switch 7 12 STIRRER PCB ELS32006 R1 The Stirrer PCB provides driving voltage for two DC motor located on the stirrer arms Generates 5V power for LLS cards Generate logic signal corresponding to tank pressure sensor The flow of signals for stirrer DC motor driving voltage is from FPGA gives logic signals corresponding to speed required to Baseboardl to Backplane2 to Stirrer card to Backplane2 to DC motors The flow of signals for the LLS power supply is from Stirrer card to Backplane2 to the three LLS cards 7 12 RCT ELS52004 RO The RCT card reads the voltages proportional to the reaction tray temperature and maintains the reaction tray temperature at 37 C 0 2 C Three thermal sensors located in the RCT are the inputs to this card The card drives three heaters located in the RCT 7 14 MOTOR DRIVE ELS52
144. only after the analyser and the lamp has M reached thermal stability after having completed a warm up time of at least 30 minutes In the SERVICE CHECK menu click on the PHOTOMETER button and the below screen will be displayed Click on the AUTO SPAN SET button and then click on the START button the analyser will automatically start a cuvette rinse and prepare a fresh clean cuvette fill it with deionised water and place it in the light path and will automatically check the transmitted light from this from this cuvette and adjust the gain of each wavelength of the photometer to obtain an acceptable signal level for processing of individual wavelengths 52 XL 600 Photometer Auto Span Set Normal Abnormal 1021232554 5 552572 85159 11 712 Send AutoSpan Gain indicators Manual Span Set Help 1 To start AutoSpan Set Click on Auto Span Set Span Set Option and Click Start On completion Auto Span Complete message will be displayed in the window 2 View Manual Span Set To view offset and gain Click Manual Span Set Manual Span Set Select Detector Wavelength option amp click required wavelength Span Set Value from list Offset Volt 3 To perform Manual Span Set 253 Perform instruction 2 Enter required Offset amp gain in the corresponding text Gai n box gt gt 2 abs boxes amp click Start button 4 Stop Manual Span C
145. or measures Potential mv Microprocessor measures 1 Potential mv Reference electrode body AgCl Coated Silver Pin High Concentration KCL Signal to the Micranracessar Resistance Ceramic Plus Ionic contact thru High Concentration KCL Internal Filling Solution Membrane ISE Module Page 14 5 ISE Module CHEMIX 800 SERVICE MANUAL 14 4 ELECTRODES Medica electrodes are maintenance free and are warranted on a prorated basis for up to 10 000 samples or 6 months whichever occurs first Cleaning Solution aspirated from an operator designated sample cup is used at least once a day at the end of the day in order to minimize protein buildup in the fluid lines A two point calibration of the ISE module is also done at least once a day at the beginning of the first sample run If the user is running more than 50 samples a day cleaning must be performed at 8 hours intervals by the host analyzer prior to calibration The entire double junction reference electrode is disposable The reference electrode is filled with sufficient so that no filling solution must be added during the lifetime of the electrode The lifetime of the reference electrode is 6 months or 10 000 samples No addition of internal filling solution is required for this electrode Electrodes require celebrant sampling at 30 minute intervals for reliable operation but this is completely controlled by the Electrolyte Measurement System witho
146. pensed into a cuvette by reagent probe and set amount of sample is dispensed into it by sample probe Dilution possible for repeat run Direct reduced increased volume runs are also possible Repeat run e Execution by repeat run list or auto execution e Auto execution according to abnormal marking and or range over Reduced increased volume repeat run also possible Sample e Sample bar code ID barcode reader provided as standard identification e Position ID for STAT samples Ref VER 05 05 05 Page 1 8 INTRODUCTION amp SPECIFICATIONS Reagent unit Item Description Type Turn table type reagent tray Reagent tray Common reagent tray for reagent 1 2 Reagent tray suitable for Hitachi bottles Reagent cooling temperature 4 to 8 cooled with refrigeration unit Reagent bottles 30 positions for 20 ml and 30 positions for 70 ml Reagent dispensing Pipetting system with plunger driven by stepping motor o RI dispensing in the 0 5 cycle o R2dispensing in the 25 cycle Reagent probe Micro pipette with level sensor Outside washing solution Preheated de ionized water Inside washing solution Preheated de ionized water Equipped with vertical obstruction detection facility to prevent probe crash Reagent steps 1 step or 2 step Reagent volume Reagent 1 60 300 ul adjustable in 1 ul step Reagent 2 0 or 10 300 ul adjustable in 1 ul st
147. proportional to the light path of the color solution diameter of the cuvette that is if the cuvette diameter is doubled the light absorbed will be doubled Incident light Transmitted light 10 gt Photo sensor Meter Light Absorbed By the colored solution Since the total incident light light absorbed light transmitted it follows that 1 Transmitted light Absorbed light Therefore as the absorbed light Absorbance increases the transmitted light will decrease As we increase the concentration of the colored solution the light absorbed increases and we find that the transmittance varies inversely and logarithmically with concentration Absorbance Absorbed light Log Transmittance 100 Log 100 Transmittance Absorbance Absorbed light Absorbance Absorbed light Log I Transmittance Absorbance Absorbed light Log 100 Log 96 Transmittance Ref CHX VER 05 05 05 2 3 Principle of Analysis PRINCIPAL OF ANALYSIS Concave Holographic Grating Focusing lens assembly Detector Photodiode array CHEMIX 800 PHOTOMETER SYSTEM Ref CHX VER 05 05 05 Page No 2 5 Principle of Analysis Principle of Analysis CHEMIX 800 SERVICE MANUAL 2 2 SEQUENCE OF OPERATION The instrument works on the principle of light photometry and a combination of robotics and hydraulics that are computer controlled
148. r Icon If version conflict message is displayed click on NO TO ALL Installation procedure is then completed Ref CMX VER 05 05 05 Page No 5 16 INSTALLATION 5 7 POWERING UP THE ANALYSER Voltage amp frequency Single phase continuous stabilized AC 220volts 10V 50 Hz AC 110volts 10V 60 Hz factory setting The CHEMIX 800 comes equipped with a three pin power cord The type of cord and plug depends on the source voltage for the system If extreme and sudden Voltage fluctuations exists then the use of an On line Un interrupted power supply is strongly recommended Grounding Perfect earthing must be provided at the power source with all applicable local requirements a grounded 3 pin power plug only should be used Plug points Four 5 amp sockets must be available near the analyser Four sockets are required one each for the analyser computer monitor and printer It is recommended that two extra sockets be provided near the analyser for use by a measuring equipment or engineering tool if required while servicing Example Oscilloscope Soldering iron etc Heavy duty electrical devices like Air conditioners refrigerator s ovens etc should not be operated on the same electrical lines as the Analyser Failure to properly ground the CHEMIX 800 bypasses important safety features and may result in an electrical hazard The 3 pin power chord plugs shipped with the analyser computer printer and monitor may not
149. r to enable the analyser to rest on the footrest only the castors should be in mid air After installing the analyser at he final required position rotate downwards the footrest the entire load of the instrument should be borne by the foot rest The castors of the analyser should be in mid air NOTE The analyser should be properly levelled preferably using a sprit level to ensure 1 Proper and efficient drainage of condensed water within the reagent tray well 2 Proper and efficient drainage for various other drain line liquids as many of the drainages provided within the analyser are of the natural Drain type 3 To obtain accurate reagent bottle dead volumes Gently lift the top dome of the analyser and gently slide the Sample arm upwards making sure you do not damage the Sample probe once you have reached the top most position rotate it and position it over the trough Remove the protective material and any debris from within the sample tray well Gently slide the Reagent 1 arm upwards making sure you do not damage the probe once you have reached the top most position rotate it and position it over the trough Gently slide the Reagent 2 arm upwards making sure you do not damage the probe once you have reached the top most position rotate it and position it over the trough Remove the protective material and any debris from within the reagent tray well Gently slide the Mixer 1 and Mixer 2 arm upwards making sure
150. rotates to the offset position pauses a while and then positions its self below the sixth laundry probe where its contents are emptied into the regular waste container Cuvette number 1 now rotates to the offset position pauses a while and then positions its self below the seventh laundry probe where its contents are emptied completely into the regular waste container by the drier probe Cuvette number 1 now rotates to the offset position pauses a while and then positions itself in the reset position in this position no work is done Cuvette number 1 now rotates to the offset position where the sampling operation starts Reagent 1 addition Reagenti probe rinses itself both internally and externally by activating both the RIPT 8 R1PP CKD valves of both the trough and Reagent 1 dilutor syringe The reagent tray then rotates and positions the requested reagent at the Reagent 1 pickup position The Reagent 1 probe then rotates and positions its self over the reagent bottle starts moving down the Reagent 1 probe liquid level sensing is now active it continues to move down until it senses the presence of reagent Once the presence of liquid is sensed it moves down a little further into the reagent and then stops The reagent 1 Syringe moves down and aspirates the defined volume of reagent for that particular reagent The reagent probe then moves up rotates and places its self over cuvette number 1 and partially moves down over the cuv
151. s check list Transasia reserves the right to change without notice the accessories supplied with the CHEMIX 800 OPERATOR MANUAL SOFTWARE CD TRANSDUCER UNIT ASSY WATER AND WASTE LEVEL SENSING PLATFORM 20 Litres CAN FOR DI WATER 20 Litres CAN FOR WASTE BIO HAZARD WASTE CAN 10 Litres DETERGENT CAN 10 Litres CUVETTES 72 Nos within the machine 5 Nos extra REAGENT TRAY ASSY REAGENT TRAY COVER SAMPLE ROTATING TRAY ASSY DISC 1 50 WITH STANDARD PLATE MAINS UNIT TO COMPUTER INTRFACE CABLE POWER CHORD 15 2 PIN TOP PVC SUPPORT FOR 20 ML REAGENT BOTTLES Installation SAMPLE CUPS 500 REAGENT BOTTLE 20 ml WITH CAPS 25 REAGENT BOTTLE 70 ml WITH CAPS 25 REAGENT BOTTLE 20 ml WITH CAPS AND BARCODE LABELS 25 REAGENT BOTTLE 70 ml WITH CAPS AND BARCODE LABELS 25 TEST TUBES 5 ml WITH BARCODE LABELS 5 TEST TUBE ADAPTORS 100 Dia 4 X 6 Polyurethane Tube for connecting the DI Water can 1000 mm Tubing for connecting the BioHazardus waste can Tubing for connecting the waste can Tubing for connecting The detergent can PERSONAL COMPUTER WITH MAINS CORD OPTIONAL KEYBOARD OPTIONAL MOUSE OPTIONAL 15 MONITOR WITH MAINS CORD OPTIONAL EPSON LX 300 PRINTER WITH MAINS CORD AND COMMUNICATION CABLE OPTIONAL COMPUTER TROLLEY OPTIONAL 25 INTERFACE CABLE 500 POWER CORD 15 A 3 PIN TOP 3 metres 50 PVC BOTTLE SUPPORT FOR REAGENT 50 SAMPLE CUPS 50 REAGENT BOTTLE
152. s of the probe NOTE Drg Z Namur A FLUNGER MOVEMENT SHOULD BE FREE mM oo ASH B PLUNGER SHOULD IN LINE WITH SLOT AXIS WITHIN 13 REDTDEZEISRLCI C SYRINGE MOUNTING SCREW TEGHTENING TORQUE 85 44 amp S S ASH PRO 6 S Home Position Sensor wr TRANSASIA BIO MEDICALS LTD I vv s SYRINGE ASSEMBLY PROCESS PR 0 THE UDCUMENT THE PREIPERTY CIF BIEI MEIMCALE 114 SHALL NET COPEN MELOLOSEN REPRIDDUEED TO ANY THRO PARTY WITHOUT THE MM WRITMR THE COMPANY AUTHORITY 3 02 00 00 000 ASM PR 01 4 9 3 CRU ASSEMBLY A Function The Cuvettes are cleaned up through the Nine positions of the CRU One position is NULL meant for taking out the cuvette blank readings The sequence of the cleaning steps are as follows Step 1 Step 2 Step 3 Step 4 Step 5 Step 6 Step 7 Step 8 Step 9 Aspiration of Biohazard waste and dispensing of Cleaning Solution Aspiration of waste and dispensing of DI water Aspiration of waste and dispensing of DI water Aspiration of waste and dispensing of DI water Aspiration of waste and dispensing of DI water Aspiration of waste and dispensing of DI water NULL Cuvette Blank Reading Aspiration of left over water Aspiration of left over water and
153. sent in the CHEMIX 800 can produce severe electrical shocks Place the Analyser and the computer in the OFF position and disconnect all line chords before attempting any replacement procedure Electrostatic sensitive components present on the PC boards in the CHEMIX 800 require you to ground yourself even when the Analyser is in the OFF position otherwise damage can occur to the Analyser electro sensitive components and PC boards ELECTRICAL DESCRIPTION SMPS 24V 6 5A SMPS 4BV 2 2 SMPS BV SMPS 12V 184 SMPS 15V SMPS 12V 5A SMP9 38V 2 5A ______ ROT EXHAUST FAN CHEMIX 800 SERVICE MANUAL ow ava wal TT 008 0 0360 l 011 11111111 SIVOITQHA OIH VISVSNVAL 3009 VSIAS Sd WS AOLL z008SQM ON LXL N 8 Dad 1 M Sd NS ov 0041 JN i 8905 77 95 52 3215 02 3HIM ON VZIRYE SANS 1 N oossamon lt VZIABF SANS 1 N roossamon VS S AVZ SAAS 1 ro noisuasni
154. ses deionized water The seventh probe only aspirates the water that was dispensed in the fifth stage and the eight stage is for drying the bottom of the cuvettes Note All probes are spring loaded and they go right down and slightly touch the cuvette bottom 1 2 3 4 5 THIS DOCUMENT IS THE PROPERTY TRANSASIA BIO MEDICALS Ltd IT SHALL NOT BE COPIED DISCLOSED REPRODUCED OR TRANSMITTED TO ANY THIRD PARTY WITHOUT THE PERMISSION IN WRITING FROM THE COMPANY AUTHORITY SUCTION PROBE ASPIRATION TUBE ORER PROBE ASPIRATION TUBE PED o CUVETT DRIER ASPIRATION TUBE WITHOUT CHAMFER SMASH PROBE DISPENSING TUBE ASPIRATION TURE WITH CHAMFER WASH PROBE DISPENSING TUBE ASPIRATION TUBE WITH CHAHFER TUBE WITH CHAMFER wv DETAL aw am wt MATL SURF TREAT HEAT TREAT natl sur TREAT Al NAE TRANSASIA BIO MEDICALS LTD vuvea 400072 DO NOT MEASURE DRAWING AL DMENSONS mn SHEET she Tet MOD BY VALUE IN microna Ra LAUNDRY ASSEMBLY DRG REY SYSTEM 5 sys code 7 di 5M HYDRAULIC ADJUSTMENTS AND VERIFICATION PROCEDURE 11 Hydraulics Adjustments And Verification Procedure 11 1 PRESSURE TANK ADJUSTMENT PROCEDURE 11 2 LAUNDRY FL
155. specially formulated to be sensitive to sodium ions the Potassium and chloride electrodes employ similar designs with appropriate selective membrane materials The potential of each electrode is measured relative to a fixed stable voltage established by the double junction Silver Silver chloride reference electrode An ion selective electrode develops a voltage that varies with the concentration of the ion to which it responds The relationship between the voltage developed and the concentration of the sensed ion is logarithmic as expressed by the Nernst equation E Eo RT log oc C nF Where E The potential of the electrode in sample solution Eo The potential developed under standard conditions RT nF A temperature dependent constant termed the slope Log Base ten logarithm function Oc Activity coefficient of the measured ion in the solution C Concentration of the measured ion in the solution Ref CMX VER 05 05 05 14 4 ISE MODULE ELECTRODE MEASUREMENT DIAGRAM Sample Port 1 Samnle Sample Detector Optically Detects air Bubble in Flow v Samnle Na Electrode 2 K Flectrode 21 M Flectrode 2574 ER Flow thru Membrane Assembly Sample Detector Optically Detects air Bubble in Flow Pumn V To waste pump Ref CMX VER 05 05 05 Signal to nrocessor Microprocessor measures Potential mv Micronrocess
156. stallation This section deals with the installation of the CHEMIX 800 biochemistry analyser Only a trained service representative should install the Analyser Contact your local service NOTE representative for installation and relocation of the instrument Problems resulting from the installation and relocation of the Analyser by anyone other than a authorised service representative will not be covered under warranty 51 INSPECTION AND ACCESSORIES CHECKLIST 5 2 UNPACKING THE ANALYSER 53 INSTALLING THE ANALYSER 5 4 PREPARING THE ANALYSER CONNECTING EXTERNAL ACCESSORIES AND PERIPHERAL DEVICES 5 5 COMPUTER SETTINGS 56 SOFTWARE INSTALLATION 5 7 POWERING UP THE ANALYSER 58 VERIFYING PROPER MECHANICAL FUNCTIONS 59 VERIFYING PROPER HYDRAULICS FUNCTIONS 5 10 TEMPERATURE VERIFICATION PROCEDURE 5 11 PHOTOMETER VERIFICATION PROCEDURE 5 12 BCR Alignment Procedure 5 13 ANALYTICAL CHECK PROCEDURE Ref CMX VER 05 05 05 Page No 5 1 Installation CHEMIX 800 SERVICE MANUAL 5 1 INSPECTIONS AND ACCESSORIES CHECK LIST The Analyser is fully inspected before leaving the factory and carefully packed to withstand shocks in transit On receiving the analyser check the package externally make sure that there is no external visible damage to the shipping container If there is damage please make a note of it if possible photograph it and inform Transasia immediately Verify with the invoice if all the boxes have arrived Accessorie
157. ste can 10 litres Bio hazardous waste can and the10 litres Cleaning solution can and place them on to their respective labelled slots on the Liquid Level Sensing Platform Fill the Deionised Water can with 20 litres of fresh deionised water Remove the tubing s from the accessory box Connect one end of the 1 meter 4 x 6 mm Polyurethane tube to the analyser outlet marked WATER and connect the other end into the Water can nozzle Now connect the large diameter silicon tube to the analyser outlet marked WASTE and connect the other end of the tubing into the 20 litre Waste can nozzle Connect the 4 x 6 mm 1 meter length silicone tube to the analyser outlet marked BIO HAZARDOUS WASTE and connect the other end to the 10 litre Bio hazardous waste can nozzle Connect the 2 x 4 mm 1 meter length silicone tube to the analyser outlet marked DETERGENT and connect the other end to the 10 litre Cleaning solution can make sure that the White Teflon weight provided at the end of the tube touches the bottom of the Detergent can Fill 10 litres of working cleaning solution into the Cleaning solution Can to prepare Working Cleaning solution Add 1 bottle of CHEMIXWASH KIT Part no REKT910 4x50 ml to 10 litres of Deionised water Take care that all the above mentioned tubes reach their respective containers withoul any sharp bends or obstructions NOTE The waste consist of a natural drain it is very important that the large silicon wa
158. ste tube from the rear of the analyser to the Waste can be slanting downwards there should not y bends and should slant in the downwards direction If not then this could cause a back flow of waste solution out of the SPT R1PT R2PT or STIRRER troughs which would cause splutter all over the top of the analyser Or could result in noisy un required big gargling sounds being created by the waste lines Ref CMX VER 05 05 05 Page No 5 10 INSTALLATION Deionised Water can Detergent can Bio hazardous waste can and Waste can connections O oo Q O Water Detergen Bio Hazardous Waste Waste Ref CMX VER 05 05 05 Fiaure 5 30 Page No 5 11 Installation Installation CHEMIX 800 SERVICE MANUAL 5 4 PREPARING THE ANALYSER CONNECTING PERIPHERAL DEVICES Place the computer keyboard mouse and monitor on a trolley table Connecting the mouse keyboard and monitor to the computer as mentioned in the Computer manual which is enclosed within the computer box For further assistance on installing the computer system you could contact your local Computer distributor the list of Distributors Service centres worldwide is mentioned in the computer manual Unpack the serial inter face cable from the accessories box and connect the D9 connector to the serial port 1 of the computer Connect the other end to the RS 232 connector located on rear panel of the instrument as shown in figure 5 40 Figure 5
159. tation Sensor UP Sensor V PRR 1 2 3 SET SET STEWS WiTH RAT PONT 67 31 3 pc 1 5 1 5 jM ACA A A 1 SAKE SET SCREWS WITH RAT POMT BN 3 1 TRANSASIA BIO MEDICALS LTD CE mm v vv voro ummmam ASSEMBLY PROCESS 1 mum 1 9 5 SAMPLES TRANSPORT ASP ASSEMBLY A Function The Samples Transport ASP Assembly consists of Base Assembly and the Tray Assembly Two Discs namely Disc 1 and Disc 2 are provided each accommodating 50 5 of samples numbered 1 to 50 and 51 to 100 An emergency tray containing 32 positions 20 12 is also provided This part of the tray can easily be removed and reassembled ensuring ease of use For Standards and controls a separate disc containing 32 positions 20 12 is also provided The ASP assembly is capable of identifying the barcode labels stuck onto the sample tubes by means of Sample Barcode Reader B Components of ASP assembly Component Function Operation Rotation Motor Stepper Motor Imparts rotary motion to the ASP Home position Sensor Opto interruptor Senses Home position of the ASP Position Sensor Opto Interruptor For sensing the rotary position of the ASP Tray ASP Container This container which is a stationary
160. the Customer MONTH Name of the Operator Model CHEMIX 800 Serial No 1 2 3 4 5 6 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 DAY Start of Day Empty waste can Empty bio hazardous waste can Fill deionised water can Fill cleaning solution can Check cal A solution level Clean the analyser external surface Replace printer paper Clean computer keyboard amp monitor Perform cuvette rinse amp check blank Perform an auto span check Verify reagent tray temperature Replenish or replace reagents End of Day Discard Sample amp Control cups tube Perform a water save Back up of all patient reports Place analyser in the stand by mode Initials of person performing Maintenance Weekly maintenance 15 week 2 week 3 week 4 week 5 week Clean the waste can Clean the bio hazardous waste can Clean and fill deionised water can Clean the cleaning solution can Check the levels of cal A solution Clean the analyser external surface Clean computer keyboard amp monitor Maintain proper room cleanliness Clean Sample Reagent 1 amp 2 probes Clean the stirrer 1 and stirrer 2 paddles Clean the laundry probes Clean Sample amp Reagent transport Clean Sample Reagent 1 amp 2 syringe Perform an auto span check Perform cuvette rinse amp check blank If Necessary Ref CMX VER 05 05 05 Page No 12 13
161. time of 10 seconds For 2 step assay using and R2 o Ist reaction 240 seconds 4 minutes 2nd reaction 370 seconds 6 minutes 10 seconds for a cycle time of 10 seconds No 1 5 Introduction amp Specifications Introduction amp Specifications CHEMIX 800 SERVICE MANUAL Test selection Setting of tests one by one or with profile key for each sample Group order entry is possible Setting from host computer via interface optional Setting according to bar code data on sample container Calibration Maximum 40 calibrators can be used 10 calibrators maximum per test Selective calibration is possible Dead volumes User programmable dead volumes for sample standard and reagent positions Mixers Type Immersion mixing by rotating mixers Two mixers 3 mixing speeds Mixing positions o The I position Right after sample dispense into the first reagent o The 2 position 1 reagent sample R2 Maintenance Programmable maintenance actions Prime Wash ISE maintenance Barcode identification Sample tube barcode ID NW7 code 39 code 128 2 of 5 interleaved 2 of 5 standard ISBT code 128 Reagent barcode ID Automatic bar code scan performed whenever reagent tray lid is removed and kept again Water supply unit Water consumption Less Than 13 5 liters hour Manufactures and supplies Type 2 quality by NCCLS standards ion exchange water optional Quality
162. tinuity between all the ground points Place one end of the probe on the AC input ground terminal of the analser and the other on the the upper chassis of the instrument it should ideally be zero ohms repeat the same for the lower half of the instrument Ref CMX VER 05 05 05 Page No 12 2 PREVENTIVE MAINTENANCE VERIFYING PROPER VENTILATION Make shure there is at least 0 5 meters of space between the wall and the instrument on all three sides to enable proper ventilation There should not be any Stationary items or objects in the vinicity that hinder proper access to the analyser There should not be a direct air from the airconditioning system on to the Analyser VERIFYING EXTERNAL INTERFERENCES Heavy duty electrical devices like Air conditioners refrigerator s ovens centrifuges etc should not be operated on the same electrical lines as the Analyzer or in the close vicinity of the analyzer The room should be free of any vibrations from heavy duty devices like Centrifuges and Compressors The room should be free from strong magnetic fields caused by other medical equipment like CT Scans etc Mobiles phones should not be used very close to the analyser VERIFYING PROPER ROOM LIGHTING There should be sufficent room lighting to enable efficent operator use and clear visable access to the internal components of the instrument during serviceing VERIFYING PROPER LABORATORY CLEANLINESS PRACTICE The instrument and the
163. to obtain a high degree of precision and accuracy The sample under test is pipetted into the cuvette along with the reagent this reaction is then read at defined time interval of 10 seconds to obtain their optical densities The entire operation can be divided into the following sequence 1 Getting ready for Sampling 2 Cuvette rinsing cleaning 3 Reagent 1 Addition 4 Sample addition 5 Stirrer 1 Mixing 6 Reading Ge Reagent 2 Addition optional 8 Stirrer 2 Mixing optional 9 Reading optional 10 Reporting 11 Removal emptingof old biohazard reaction waste from the cuvette Getting ready for Sampling Once the workload is scheduled in the computer and the START PATIENT run key is clicked all mechanical assemblies and sub assemblies gets initialized come to their respective HOME positions The CRU starts the cuvette rinsing process The washing assembly consists of 8 nozzles nozzles 2 to 8 consist of 3 hollow probes one for dispensing and the other two for aspirating their operation is described below Nozzle 1 Aspirates the bio hazardous waste and dispenses cleaning solution Nozzle 2 Aspirates the cuvette contents and dispenses deionised water Nozzle 3 Aspirates the cuvette contents and dispenses deionised water Nozzle 4 Aspirates the cuvette contents and dispenses deionised water Nozzle 5 Aspirates the cuvette contents and dispenses deionised water Nozzle 6 Aspirates the cuvette conten
164. to sensor out put has to be checked and verified 92 SPT Syringe up down The connecters up down motor syring Error during run opto sensor out put has to be checked and verified Ref CMX VER 05 05 05 Page No 13 4 ISE MODULE 14 ISE Module This section consists of the following 14 1 ISE MODULE MEASUREMEN FEATURES AND BENEFITS 14 2 TECHNICAL SPECIFICATIONS 14 3 ISE MEASUREMENT THEORY 14 4 ELECTRODES 14 5 MAINTENANCE SCHEDULE 14 6 ERROR CODES LIST 14 7 REAGENT CONSUMPTION 14 8 ACCEPTABLE CALIBRATION RANGES 14 9 ISE MODULE MECHANICAL ASSEMBLY Ref CMX VER 05 05 05 Page No 14 1 ISE Module ISE Module CHEMIX 800 SERVICE MANUAL ISE MODULE MEASUREMEN FEATURES AND BENEFITS Features Integral sample port entry Benefits Minimal sample carry over Small sample size 60ul Electrodes mounted close to the electronics Minimal electronic noise improves precision Sample port adjacent to ISE sensors Minimal sample size and carry over Rapid operation 30 seconds cycle time Rapid results Easy to access sensors Simple maintenance No Membranes need to be serviced Minimum down time Easily accessed pumps Easy maintenance Two bubble detectors Two point calibration Reliable sample processing assured High accuracy and precision One point calibration with every sample With every sample the calibration is assured h
165. tomatic Manufacturer of the Analyzer TRANSASIA BIO MEDICALS LTD 8 Transasia House Chandivali studio road Mumbai 400076 INDIA Production Facility TRANSASIA BIOMEDICALS LTD SDF VI PHASE I UNIT NO 162 SEEPZ ANDHERI EAST MUMBAI 400096 INDIA FOREWORDS 1 CHEMIX 800 THIS PAGE IS INTENTIONALLY LEFT BLANK FOREWORDS 2 HEMIX SAFETY WARNINGS AND NOTICES B Meanings of warning symbols WARNING ABOUT Biohazard Electric shock High temperature Injury Action to be taken as directed by the OPERATOR S MANUAL SAFTY WARNINGS 1 CHEMIX 800 BWARNING LABELS The following warning labels are affixed on the places that are the potentially hazardous WARNING l Potential hand exposure to probe Keep hands away WARNING ABOUT PLACES WARNING On the 4 piece Top Plate POTENTIAL HAND EXPOSURE TO PROBE KEEP HANDS AWAY DO NOT OPERATE MACHINE WITH COVER OPEN DO NOT TOUCH MOVING PARTS WHEN N OPERATION PERSONNEL INJURY MAY RESULT DUE TO PROBE ARM MOVEMENT TO REDUCE DAMAGE TO THE INSTRUMENT DO NOT SPILL SAMPLE OR REAGENT ON THE MACHINE WARNING ABOUT PLACES CAUTION On the Rear Panel DO NOT OPERATE MACHINE WITH COVER OPEN DO NOT TOUCH MOVING PARTS WHEN IN OPERATION PERSONNEL INJURY MAY RESULT DUE TO PROBE ARM MOVEMENT TO REDUCE DAMAGE TO THE INSTRUMENT DO NOT SPILL SAMPLE OR REAGENT ON THE MACHINE A WARNING
166. ts and dispenses deionised water Nozzle 7 Aspirates the cuvette contents Nozzle 8 Dries the reaction cuvette Cuvette number 1 is positioned under the first laundry probe where its previous contents are emptied into the Bio Hazardous waste container and cleaning solution is dispensed Cuvette number 1 now advances by a single position and positions itself below the second laundry probe where its contents are emptied into the regular waste container and deionised water is dispensed Cuvette number 1 now advances by a single position and positions its self below the third laundry probe where its contents are emptied into the regular waste container and deionised water is Ref CMX VER 05 05 05 2 6 PRINCIPAL OF ANALYSIS dispensed Cuvette number 1 now advances by a single position and positions its self below the fourth laundry probe where its contents are emptied into the regular waste container and deionised water is dispensed Cuvette number 1 now advances by a single position and positions its self below the fifth laundry probe where its contents are emptied into the regular waste container and deionised water is dispensed Cuvette number 1 now advances by a single position in this position no work is done Cuvette number 1 now rotates to the offset position pauses a while and then positions its self in the light path where the cuvette blank reading Water Reading is measured Cuvette number 1 now
167. ttom of the cuvette Select SERVICE CHECK CRU amp REACTION TRAY gt CUVETTE RINSING UNIT gt INITIALISE gt DOWN gt To adjust the vertical distance travelled by the laundry loosen and adjust the CRU DOWN lower opto sensor Ref CMX VER 05 05 05 REMARKS OBSERVATIONS In the initialised or reset position the following are the positions of the cuvettes Probe1 cuvette position 72 Probe2 cuvette position 71 cuvette position 70 Probe4 cuvette position 69 Probe5 cuvette position 68 Probe6 cuvette position 67 Light path cuvette position 66 Suction probe cuvette position 65 Drier probe cuvette position 64 Verify that all laundry probes are in the centre of their respective cuvettes and that the cuvette drier Teflon is in the centre of the cuvette 1 Verify that after the cuvette drier and suction probe goes down into the cuvette the spring loaded probe moves up by about 2mm NOTE THIS IS VERY IMPORTANT 2 Verify that the remaining five laundry probes also touch the bottom of the cuvette slightly NOTE this is not very important Page No 5 20 INSTALLATION VERIFY SAMPLE ARM ALIGNMENT NOTE The sample arm is aligned with the RCT in the reset position NOTE The sample arm alignment is done with respect to the sample cuvette only and only a verification is done at the other positions ACTION REMARKS OBSERVATIONS Initialise the system through the Service Check menu
168. udio Select Enabled 5 Power On function Select KB98 6 Onboard Serial Port1 Select 3F8 IRQ4 7 Onboard Serial Port2 IR Select 2F8 IRQ3 8 Onboard IR Function Select Disabled 9 Onboard Parallel Port Select 378 IRQ7 10 Parallel port mode Select ECP EPP 11 EPP Mode select Select EPP1 9 12 ECP Mode DMA Select 3 13 Game Port address Select 201 14 Midi port address Select 330 15 Midi port IRQ Select 10 POWER MANAGEMENT SETUP 1 ACPI Suspend type Select S3 2 USB Device wakeup from S3 Enabled 3 Wake up by PCI LAN Enabled 4 Power On by ring Enabled 4 Force Update ECSD Auto 5 Allocate IRQ to VGA Enabled 6 Allocate IRQ to USB Enabled Ref CMX VER 05 05 05 Page No 5 14 INSTALLATION PASSWORD Do not set any passwords for User or Operator Save the values and exit If there are any changes from above menu use default values SOFTWARE SETUP Partition the Hard Disk Drive into two drives C and D each of approximately 20GB Install Windows XP in drive C Install Service Pack 2 0 and above for Win XP Install printer driver Delete all temp files Install CHEMIX Application software in Drive C Copy the database in drive D Run the software and test all the features After complete testing clean the database oe9eoudogsom after proper system down Ref CMX VER 05 05 05 0 Shut down the system through Windows SHUT DOWN menu Ensure that the power is switched off only Page No 5 15 I
169. ut any need for control by the host analyzer or the operator The electrodes require a 10 times sample dilution for measurement of urine The ISE module depends on the host analyzer to perform the dilution function It is not necessary to regulate the electrode housing temperature provided that its environmental temperature does not exceed 30 C Ref CMX VER 05 05 05 14 6 ISE MODULE 14 5 MAINTENANCE SCHEDULE The Electrolyte Measurement System has been designed to require very little operator maintenance The only daily maintenance required is to run the Cleaning Solution after the last sample of the day All other parts and expendables are replacement items see schedule below Recommended Maintenance Replacement Schedule low volume user Pump Cassette 9 months Na Electrode 6 months 6 months CI Electrode 6 months Reference Electrode 6 months Reagent Refill reagent as required by testing needs Recommended Maintenance Replacement Schedule greater than 100 samples day Pump Cassette 6 months Na Electrode 10 000 samples K Electrode 10 000 samples Cl Electrode 10 000 samples Reference Electrode 10 000 samples Reagent Refill reagent as required by testing needs Ref CMX VER 05 05 05 Page No 14 7 ISE Module ISE Module CHEMIX 800 SERVICE MANUAL 14 6 ERROR CODES LIST ISE Module Error Codes
170. ve Ref CMX VER 05 05 05 Page No 5 46 INSTALLATION 5 13 ANALYTICAL CHECK PROCEDURE ABSORBANCE TEST PROCEDURE OPTIONAL A solution of Potassium Dichromate is used to test the precision of the reagent and sample pipetting Preparation of Solution A Make up a 8 826 g l solution of Potassium Dichromate as follows Dilute 0 8826 grams of Potassium Dichromate in 100 ml of de ionised water This solution will be used as a sample for the sample precision test Preparation of Solution B Make up a 1 in 60 dilution of Solution A as follows Add 59 ml of de ionised water to 1 ml of Solution A to make 60 ml of Solution B Decant this into a reagent bottle for use in the reagent precision test METHOD Sample Absorbance test Use Solution A as a sample with de ionised water as reagent A factor of 1000 is used Reagent Absorbance test Use Solution B as a Reagent and de ionised water as sample A factor of 1000 is used Twenty replicates for each test should be used to facilitate meaningful and statistical analysis of the results A Coefficient of Variation of 196 for the reagent test and 0 596 for the sample test should be regarded as requirement and should be met Ref CMX VER 05 05 05 Page No 5 47 Installation CHEMIX 800 SERVICE MANUAL CLINICAL TEST CHECK PROCEDURE Date Instrument Sr No Installation
171. water emerges from the probe that is free of any trapped air bubbles Do this till the entire tubing and probe is completely primed and free of air bubbles REAGENT 2 From the SERVICE CHECK menu select REAGENT 2 ARM click on INITIALIZE click on REAGENT OUTER click on REAGENT TO CUVETTE 82 click on R2 CUVETTE TO DRAIN CLICK on the GO BACK button From the SERVICE CHECK menu select SYRINGES then select REAGENT 2 SYRINGE click on INITIALIZE and click on the VALVE ON Check and confirm that a clear uninterrupted straight jet of water emerges from the probe that is free of any trapped air bubbles Do this till the entire tubing and probe is completely primed and free of air bubbles Ref CMX VER 05 05 05 Page 11 5 Hydraulics Adjustments amp Verification PREVENTIVE MAINTENANCE 12 Preventive Maintenance Prevention is better than cure 12 1 SERVICING A CUSTOMER SITE 12 2 MAINTENANCE SCHEDULE 12 3 UsER DAiLY amp WEEKLY MAINTENANCE LoG 12 4 SERVICE TECHNICIAN QUARTERLY MAINTENANCE LoG 12 5 SERVICE TECHNICIAN ANNUAL MAINTENANCE 06 12 6 SPARES REPLACEMENT SCHEDULE It is always recommended that the instrument is maintained by the user with proper instructions from the service personal to get the optimum output and to avoid any possible damage to the analyser Ref CMX VER 05 05 05 Page No 12 1 Preventive Maintenance Preventive Maintenance CHEMIX 800 SERVICE MANUAL 12 1 SERVICING A CUSTOMER S
172. y probe fills to 3 4 the total volume of the cuvette Verify that there is no spillage of deionised water from any of the cuvettes Observe this carefully for multiple rinse cycles DEIONISED WATER FLOW ADJUSTMENT Ref CMX VER 05 05 05 DEIONISED WATER FLOW REGULATOR 2 11 4 HYDRAULIC ADJUSTMENTS AND VERIFICATION PROCEDURE 11 3 R1 R2 SAMPLE PROBE DISPENSE VERIFICATION NOTE NO ADJUSTMENTS CAN BE MADE TO CONTROL THE FLOW OF R1 R2 amp SAMPLE PROBE DISPENSE ONLY A FLOW VERIFICATION CAN BE MADE AS FOLLOWS SAMPLE From the SERVICE CHECK menu select SAMPLE ARM click on INITIALIZE click on SAMPLE OUTER click on SAMPLE TO CUVETTE click on CUVETTE TO DRAIN CLICK on the GO BACK button From the SERVICE CHECK menu select SYRINGES then select SAMPLE SYRINGE click on INITIALIZE and click on the VALVE ON Check and confirm that a clear uninterrupted straight jet of water emerges from the probe that is free of any trapped air bubbles Do this till the entire tubing and probe is completely primed and free of air bubbles REAGENT 1 From the SERVICE CHECK menu select REAGENT 1 ARM click on INITIALIZE click on REAGENT OUTER click on REAGENT TO CUVETTE click on CUVETTE TO DRAIN CLICK on the GO BACK button From the SERVICE CHECK menu select SYRINGES then select REAGENT 1 SYRINGE click on INITIALIZE and click on the VALVE ON Check and confirm that a clear uninterrupted straight jet of
173. y to help avoiding evaporation of reagents This lid is provided with an interlock proximity switch to sense the opening closing of the RGT cover THE DOCUMENT 15 THE PROPERTT OF TRARGASIA EIU MELICALS Lhi IT SHALL TRANSMITTED TU ANT THAD PANTT WITHOUT THE PERPESSIOM IN FROM THE ader Mtg bracket UPEL DATED REPRODUCED OR COMPANY AUTHORITY Deg 7 Coda Humber 1 00 60 ASH PR 0 RET ASSEMBLY PROCESS PR 09 1 2 MM 00 0 00 ASM PR 2 2 REAGENT TRAY RGT CONTAINER 5 Rotation Motor i 0 me TRANSASIA BIO MEDICALS LTD mom v vv vvv very umma 255 en mm pum IH aa RGT ASSEMBLY PROCESS PR 10 MILES 00 Code Number EMT am y aaa C OCRA a LOCATING AW FOR OUTER RN 01 3 ALPS SOES M 7725 4 amp MOLI M M 60 600 RET ASSEMBLY PROCESS PRA L3 RGT Cover LE em TRANSASIA BIO MEDICALS LTD T DO MEASURE ma v vv covo i E ASSEMBLY PROCESS PR 1 TiS 9 7 REACTION CUVETTE TRANSPORT RCT ASSEMBLY A Function The RCT assembly consists of base assembly water jacket assembly and the cuvette ring set
174. zer in conjunction with other equipment Wipe the nozzle tips of SPT and several times with cloth or alike with rubbing alcohol before the analyzer is used At this time do not forget to put medical rubber gloves or alike on Pay attention to prevent bare skins of hands or arms from being touched by or pricked with the nozzle tip 4 The following cautions should be exercised when replacing the halogen lamp Replace the halogen lamp by a new one after a lapse of 30 minutes after the power switch of the analyzer is turned off to avoid danger of burns Keep hands away from glass part of new halogen lamp Make sure that there is no crack or breakage in the glass part 5 The following cautions should be exercised during operation Pay attention not to exceed time and volume necessary for diagnosis Keep monitoring the behavior of whole system in order to detect any malfunction Take immediate corrective measures including shutdown of operation when any malfunction is detected in the analyzer Avoid possibilities of any direct access by patients 6 The following cautions should be exercised after the use of the analyzer Turn off the power after every operation so that control is restored to its pre use state as directed Do not remove the line cord plugs from receptacles by pulling the cords so that no undue stress is developed in the cords Wipe the nozzle tips of SPT several times with clot

Service Manual (Draft Version) Clinical Chemistry Analyzer

Contents

Download Pdf Manuals

Related Search

Related Contents