PDFファイル - 医薬品医療機器総合機構
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1. 1 2 2 A 0 0 g mL2. NADH NAD NAD 1 EDTA 2K 4 2
3. k 2 3 2 8 24 Exp R1 15 mL R2 RACE 0 8 mL EU R1 R2 1 1989 15 4 p 285 291 2 Warner A et al Guidelines for Therapeutic Drug Monitoring Services The National Academy of Clinical Biochemistry 1999 p 87 3 TDM 2006 4
4. 1 0 g mL 30 u g mL 5 mm 0 050 0 290 2 15 3 3 CV 10 PE 4 3 0 700 u g mL 0 A mean 2SD n 21 2 1 FPIA 58 r 1 0 y 1 0x 6 1 y x 2
5. 2 1 300 4 g mL BZ 23 mg dL 1 000 mg dL 1 000 mg dL 14 g dL 10 cobas 2 pg mL Acetylsalicylic acid 1 000 24 1 m Aminosalicylate 1 000 8 34 p Aminosalicylate 1 000 28 8 p Anisic acid 1 000 ND Benzoic acid 1 000 ND Chlorzoxazone 500 0 65 Diflunisal 500 1 10 EDTA disodium 300 1 55 Gentisic acid 1 000 2 86 Homogentisic acid 1 000 1 89 alpha Ketobutyric acid 1 000 0 32 Methyl salicylate 1 000 6 44 Naprosyn Naproxen 500 ND Oxalic acid 300 1 22 Phenol 1 000 0 33 Salicyluric acid 1 000 1 96 Salicylamide 1 000 0 49 Theophylline 300 1 43 Uric acid 300 ND ND
6. 2012 12 3 2010 4 2 221AAAMX00144000 1 2 3 lt 4 R1 Dre NT NE API TTC 8 NADH R2
7. 5 1 000 ppm 0 19 6 7 HIV HBV HCV 121C 20 1 000 ppm 0 1 1 2 1 2
8. 00 3 6000 1 2 2 8 C 3 6000 TDM 6000 1 2 5xL 100L 20L AI 37 CC EE 2 54L 20gL 37 3 2 30
9. 3 KW 4 5 6 7 8 9 15 25C 1 2
10. 105 0014 2 6 1 0120 600 152 105 0014 2 6 1 0120 600 152 COBAS is a trademark of Roche Roche 3 3 0 5968348 001 C LOOS S96G O05968348001 C
11. 340 nm 4 5 TDM 1 20 100 u g mL 100 250 TX HE A u g mL gt 450 g mL re
12. Trinder 50 r 1 0 y 1 1x 40 y x 3 53 r 1 0 y 1 0x 2 5 VIE xi 3 USP United States Pharmacopeia 1 2 3 4
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