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BISモニタ A-2000

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1. 3 5
2. DD ooo 0 nn ep ric mt 10000008 00000 0000000000 0000 0 0 00 250 100 2 QOOOOOOU000000000000000000 Ja AdB aii 10000900000000000000000000 000 000 000 DODBBDDBBIDDOBDIDDODODDDDDUODD OFR 50 60 Hz cie e onarimi eBSOOO0O000O00000000000000000000 50000000000000 0 0000 0 0 0 00 815 d 00000 00 00000 000000 Nem 5850000000000000000000000000 S nnomTses 10000000000000080 000 000 0000 000000000000000 880 11000000090080 9500 0000000000 8 000000000 o 100000 0000000000000 0000000000 00000 000 0 000 000000 00900 0 oO oo 1 H3 D c3 EHoBgptgd E Ez LE LI Lu EE s oO oe Lu Ei EET E Lat ra E ES ert 3 D apes eS
3. H p E E rpm uir oO oOo Ll L3 m CC EZ cl 110000 n ooo EZ ES 0 ggpapnpnaunmnaad 1 11 0000000 EH Co r3 r3 r3 EH E En oo E E E Co EH EH ooo es a 3 E3 G EE a Fo 8 EE go C3 09 gg E E EE EL ESI C3 ESI c3 sE 00000000 508 0 OOOOOO 03 50 DI 20 V Peak to Peaki 0 08 00800888008 00 0 0 25 50Hz ER PUE O00 8 DUODD00 DLE EL DLE UE NN a TUE 0000000000000000000000000 0 0 00 P anandan Snan 00000080 000000000 0 00000000000000000 20000 00000 E TEE 0000000000 MEN 10000000900000000088000000000 0000 OBST 0 000 08 00 00 DO D 000 000000 i 000 0000 00 0000000 00 000 0 OOO0ndo00000000000000000000 00000 PRENNE DEDE MOM 2 0 000000008000000000000 EM 3 00 0909000090000000000000000000 0 0008500000000000 O00 e00000000000000000000 Dn 4 00 00000 0000 0000000000000 D 00000 TOO EJ r3 o OOO000000 UU EX e E now 63 3
4. EMG E Eu og zs 5 ett Lu E L3 r3 IO ec GE oog oo ES Doc Ooo 255 Lu EC E L3 CH Zo SEES J a ooo Oo oO GIE um oo m nooo E zm EE E KE L3 r3 EJ oe ELE a E oF co II 2a EE F Wo Co noo ooo SE 3 E p CH EE Es edid Ol EEE E gog E oo es oO ood gog Ss oH a r3 Oo F ES SE EIE E Em E Bi E E GENEE oO oO Oo Topo DI CH oo a OG i E rH oO E nm i E SS ooo oO l CO CS 3 3 t pa H CODE 2201 3 aE SE E oO 1 ec g H ob E a EE E3 E3 ETE3 S SC ES 1 good oO r3 r3 3 3 2 E HEE CC E 20 ELE o ao oon E oO Soc z i oO r3 E E E r3 d nd acuan ES ERES SES oe ES Co CH St Se r3 oo E zi EE ERES co E mad E ob 255 o CO EI CH o n me Oo ooo E C E I Oo r3 E d p HH oO mu r3 oo 1 oo Ooo Oo E i E SE co E 531 es WC p ES c5 E E SEE ass mu 73 Ol EC ae i S oo 03 E e ola H ri EZE l E CH 5 CH Benk Se o5 Il CH H 1 o 2 mo 2 B S E 1 E3 LB ooo E Ei SEI E Se ET LIEST Oo 1 E33 Eg GE Is EE E 53 oO l ooog p I EI oo E e Lt a Ee E R a ES pe 2 e EI E T E E T FEE oo
5. 0N 000000000000000000000000 EEN 1000000 0000000000000008000 nooo QUAZI 10 0000000800900000008000000 DD A 2000 000 9 000 000000000000000 000000000 5 3 1 1 1 SEINE 1000000000900000000000000000 000 10000009900000000000000 0000 SynchFastSlow PIC PI E 100000000008000000 0000000000 1000000800 00008000000000000 BISO 0 0 D Budd A 2000 MIN E Ss 01 850 00 00000 000000 0 0 0 0 000 D OOOOO0000 nm FFTQ 8581 D D pugugpagagagiugagagagagadan 0 0 80 a dtt OOOO SynchF astS low 858 ouazi 0000000008880 ELE LT LU TE UU uu gnunuganameemmunnmnnnnnnn n n Be mm OOO 00000 90000 00 00 9000000800 0 m 888295 0 0 0000 000 0 0 000 0000000000 1 00000000000000000000000000000 1000000000 ee DHBBBE UNE 10000000000000000 88 0100000000 BIS 0000000 13B1X00069AS005A 1 00000009000000000000000000000 BIS 00 00 13B1X00069AS004A ugggguna nn A 20000 0000000000000000 15 0 1100 0 BIS A 2000 EEGD OO 0000 15025030mw 109 0o00 0000 ON 020 70Hz E E LT T 110 25 50 100 V div 100 EZ CH E On Baal E 0 1 EZ oo CDe
6. 8 0 00000002000 0 000000 00 0 1000000000 0 000 00000000 0 0 0000000 pm SS DENTEN 000000000000000000000000000 00 S ee E 18500 0000 000000 00 000000 gef ST 1 00 00 00 0 00000 00000000000 0 00000000000 Bisoo 1000 00000 000 00 0 00000 0 0 6 0000000000000000 100000000000 00 00 0 OOOOO0000 3 288 1 00000000 10000000000 00 00000000 00 D 0 3990 70 Donn E 0000000 000000 00 0 A 1000m 0000000000000000 0 0 Volunteerstudy T U Hr Clinical Utility Study TT UU LU Volunteer Study T 0180 600 000000000 19949 3 0O000000000000000000000000000 5000 19959 1000 40 00720 Clinical 0 0 0 85 0 0 0 0 00700 0 0 850 0 0 0 Utility Study 0180 800 D 19950 6000 000 00000 00005000000000000000 19960 7000 40 003020 0000000000000 0 0000000000000000 00 0 0 0 00 30000 0 0 00 0 0 000 TERIS Gore DDN ea MS 1 000 00088 88 0 00 0 00880 0 00 000000 eee 10000000000 0 Volunteer Study n 00 D 8 0 0 0 0 00000000 DUDU UD HUDD 10 7200000000000 0 70000 00 2 Clinical Utility Study
7. g2 E Se ge um tH EZ oOo Ehe e Cu i oo oo EI Op EE 0 1 iga E Se E g oo r3 I E Boc zE pH E CH E C a as z oo oo Om or oon I oO r3 mm E oO E oO Doc um mn Oo oOo oOo ol Oo ef Ci oo Ci EZ Ci eo S ES CH l sf l ac Z uam 4 r3 zl E E oo L3 Ed eS m 1 CH G r3 oct D ao z F 2 oo oO 1 oO oOo ES E ES O p pn og ICC SS E agas oO oO C3 a oO oo z Ge E3 i 1 HH Oy oO Cl e El no Check CC Fa c BSagsSag E E CH m oO oo Ono Dr pBt Copien los som cog E ES Oo Ooo ou E run e Oo CH oO ee aoc E oc obl oc ci tcu o ESI oo Oo oo E E 222 E m cae 6 2 E cB L3 r3 Ee oo C G Oo E E oO j C3 B EI SE E ES E E oo oo z S zB r3 O oo L3 Oo I E oo CI el o H i s 2 E r3 p HH oO Ei oo Cl oO L3 i E 55 ES l 2 Bo C3 oo 10 01 3 3 agg 225 EE ogH Hi z Se Cl SE aoe os FE c E EE o oo ooo 3 e aS a oO I p B gn Cl 53 Bo ooo EZ oo oe oe oOo E Ss n oo EJ um C3 E SEES m m mm i F F z 229 ooo oo geet aie ES loc d oo fest O H oo 1 SE SE t EZ Cl oO Oond E E SES I oo oO L3 ooo sues E LJ Oo oO L3 r3 c3 a i E cn gaH
8. 232 2 oOo ago w Oo E E D 00000000000 Hg n 1 000000000000000000 0 0 0 0 1108 ODD er BN 00 0850 0 00 000000000000000000000000 i N 00000 D 00000003000000000000000000 Greg a rri EE EI Fa E E E J ee ea a E 2 1 E Oo EZ E E j 5 9 EJ Oo L3 r3 Co lt 2 E 3 2 2 E HE oO EXE dE eos SU ioo y E EE CH p ut 1 1 00000 00 0 DD 11 0 0 00 000 380 0 00 0000 0085000000000000 oo EEGOOOOOOOBISOOOO0000000000000M s DO00000000000 000 0 OOO ugggaguuagdgsesisnpaggggdadu 10 0 03000000000 EEGOOO000UD 000000000000 1110100000 0 00 2 CDD Do 0 03 H EI EIEEIETI EZE E CODE DIE EE lt Lad oO
9. 0 00000000000000 1 000000000000000 000 000 0 00 0 000 0 3020 00 000 00 0000002740000 100000100 0000000000000000 0 00280 10000000000000 0000 008500 100000 0000000 0000000 0 000 0 10000000000 0 000 000 0000 0 0 00000 0000000000000000 000 8 5 0 DOAAS 100000 0 858 0 0 00000 00000 0 00 100 0000 0 00000 00 00 000 0 0 0 00 1000000000 0000 00000 0 0 000000 0 1000000000000000 0 0 000 000000 0 D0000000000000000000000 000000 DO0000C0C0000000000000000000 000 0 DO00000000000000000000000000 D000000000000000000000000000 000 00 000000000000 00000000 0 10000 0 0 0000 0 0000000000 0 10000000000000000000 0 0000 000000000 10000000 0000 1990100000 ugaggaaga 10 aij 41 84 370 78 41 40 0 390 430 p 370 430 715 80 0 073 50 85 70 7430 80 70 076 40 83 70 Mass Genera Emory University of Hospital University Pittsburgh gaguau 11000 20 10 I 1505 0 703 5 0 0 0000 33 9 3159 BISOOO 00 12 20 3 45 73 8 45 65 5 101 125 108 820 1200 1140 1350 990 1190 OOOGd00dg EI 1000 0 1 1000 0 0 101 00 000 000 0 H 00 0000
10. oof D Dau E ood 000000 noog 6 0000000000000000 0000000000000100 1000 00 0 0 60 0 0 600 0 000 000000000 00000000000 0 1000 000 6 6 p am 88 o 100000000000 0 0 0000 00 1111900000 0 0 0 00000000 00 00 00 000000000 0 eun 1 000000 00000 0 00 000 00 0 0 1 5 6011000000000000000000 00 mm oo 00 0 0 600 000000 0000000 D EE Lea L3 11 0100100000 6 n 1 185 110100000000000 0 25
11. 1 2 12 0 8 000172000 000000000 p lt 0 001 0 4 858 00 0 0000000 05 00 11 11 8 nist SP 1 10 1011100000000000 001 0 000 000 0 11 111 000000 0000 DOOOOUOOOBISoOoOOOOOOOOOOO00000000 11101 11 100010 un 4000 500 0SPO 8m ed rm 8 210 20 D 1110 00 00000 1 2800000000 00000000 60 1 1 50 400000 111 1 1 8 0000000000 0 50000000 500 1 11101010 00000000000000000000 00 EE OOO000 OOOO 50 40 C OOOO 150 95 00000000 1 1 48 106 6kPa pdt OOOO 20 60 C OOOO 150 95 00000000 1 1 48 106 6kPa 0000 5 DUDUDUDDUDDUDUDUDUDUDUDDUDUD UU UE Da 0 0 0 00 000 1 0000 0000000000 Oo ff 1000000 00000000000 0000 Kearse L Rosow C Glass PSA et al Monotonic Changes in EEG Bispectral Index Correlate with Targeted Plasma Conc
12. e ong E Ei CH a oo B LTLI LE H LI 0000000000000000000 0 8 08 0 0 i 000000000000000 00 0000 00000 8 0 11 8 8 8 0 0 1000000 000000000000000 000000 0
13. 000 85 PU 0 0000 000000000 0000 0000 G0p lt 0 00109 O0p lt 0 0100 000000000 oa nagn 220 50 22 45 74 13 oe 80 14 000 ET VE AE LE S a 510 109 61 100 45 DUDODDUDUUDDD 950 12 26 10 000 14 520 931 8 120 10 500 6 16 5 17 7 159 14 22 11 15 17 300 10 28 6 39 0 9 080 11 480 539p 7 390 13317 10 530 15 410 11 13 7 16 8 510 13 360 6340 8 170 43 51 35 420 52 000 37 47 D 33 400 41 540 31 42 0 28010 35230 2 0000000000 0 00000 BP 5 0 00100 0 0 000 0 1 0 0000000000000 0000000000 0000 000m adu 3 PACUQOOOOOM00000000000000000 O Global nursing impression OGN 51 10 5 00
14. 0020100 119 80 0 40 0 0000 2130082600029000 20079 120 190 0 1 300 0000020000000000 oooga 35777000 BIS A 2000 1 0 815 1 J 0000B8S00000000000000000000000 00000000 100000000000000000 000000000000 850 0 0 0 00 880 000 000000000 00 1000000000000800000000000000000 1 00 0008 D Dap 000 0000 85806 2 0 0000 SynchFastSiow D D D 0 00080 00 DO 08 0 MA re ee eee O00 00000000000000000000000o0000 RE DEENEN 000 00 0 0008 00 000 86950 0 0 000000
15. Propofol Alfentanil N O Anesthesia Anesthesiology 1996 85 3 A A1056 Dajun Song Girish P J oshi Paul F White Titration of Volatile Anesthetics Using Bispectral Index Facilities Recovery after Ambulatory Anesthesia Anesthesiology V87 No 4 Oct 1997 u ut uaa 000000000 1 31 4 TEH 0120049 0990 DUDUUI BASE aa ae 03 5996 8000 0 0 0 Fak 03 5996 8091 00 00000000 00 Covidien 0000000 8030100000 00000 00000 000000 6135 00000000 Covidien go000000 5 5
16. entrations of Propofol and Midazolam Anesthesia Analgesia 1996 825220 Bloom MJ Whitehurst S Mandel M et al Bispectral Index as an EEG Measure of the Sedative Effect of Isoflurane Anesthesiology 1995 7 4 A195 e Glass PSA Bloom MJ Kearse L et al Bispectral Analysis Measures Sedation and Memory Effects of Propofol Midazolam Isoflurane and Alfentanil in Healthy Volunteers Anesthesiology 1997 86 4 836 847 Kearse L Rosow C Connors P et al Propofol Sedation Hypnosis and Bispectral EEG Analysis in Volunteers Anesthesiology 1995 83 3 A A506 Kearse L Rosow C Sebel PS et al The Bispectral Index Correlates with Sedation Hypnosis and Recall Comparison Using Multiple Agents Anesthesiology 1995 83 3 A A507 Flaishon R Sebel PS Sigl J Bispectral Analysis of the EEG for Monitoring the Hypnotic Effect of Propofol and Propofol Alfentanil Anesthesiology 1995 83 3 A A514 e Flaishon R Windsor A Sebel PS Sigl J Recovery of Consciousness After Thiopental or Propofol Anesthesiology 1997 86 3 613 619 Glass PSA Sebel PS Rosow C et al Improved Propofol Titration Using the Bispectral Index BIS Anesthesiology 1996 85 3 A A351 e Sebel PS Payne FB Gan TJ et al Bispectral Analysis BIS Monitoring Improves PACU Recovery from Propofol Alfentanil NO Anesthesia Anesthesiology 1996 85 3 A A486 e Payne FB Sebel PS Glass PSA et al Bispectral Index BIS Monitoring Allows Faster Emergence from

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