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1.
2. 005ppm 3 34 75 4 6 2 5
3. p20 21 18 1 mm Ma RNC PENIS 5 er 10 0 05ppm 1 M UE N Yo ST ME AMAM T
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5. 2 200mL 24
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7. pH 36 32 DPD p
8. 17 5 1 3 5 9 9 12 79 9 1 28 30 35
9. 2 I 1 2 3 4 RE 5 6
10. I Zi 1
11. 10 4 I 1 200 mL
12. 2008 5 Helicobacter pylori 1995 9 99 2005 12 World Organization of Digestive Endoscopy OMED 5
13. FDA 650ppm 20 10 60ppm
14. 4 9 17 9
15. 7 25 1 2 1 10
16. I 1 1 15 2 3 4
17. II IV V 3 I 1
18. 5 59 6 7
19. 2 3 16 I gt gt L L
20. 1 3 6 2 2
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22. 2008 5 23 1 1 2 3 I I 4 I I I 5 I II I I lt 4 HAs O d co oo OO Cl Co PI w 15 17 18 24 26 28 29
23. 5 ATI 6
24. personal protective equipment C HCV B HBV Helicobacter pylori 8 2 HIV 2
25. 2 lt 3 1 Pseudomonas 9 9 197 I 1
26. 7 8 9 10 0 1ppm 11 1 1 12 TV 13 12 2
27. 6 I 1 C Spaulding 2 1 59
28. 2 2 26 3 27 1 ENDOSC FORUM Digest Dis 1995 11 18 23 2
29. 3 24 4 99
30. 3 22 5 6 589 5 23 2 8 38 52
31. 4 2 4 21 R2 2 J 25 77 9 2 2 25 7 10 ids 3 21 28 arse 3 59 28 2 lt 2 259 20 7 10 396 40 21 28 3 59 50 28 30 40 1 2
32. 3 5 4 4 3 5 5
33. 1996 16 57 63 3 Gastroenterol Endosc 1998 40 2022 2034 4 2004 32 82 96 5 3 2006 6 Rey JF Bjorkman D Duforest Rey D Axon A Saenz R Fried M et al OMGE OMED Practice Guideline Endosocpe Disinfection 2005 Dec 14 http www omed org downloads pdf guidelines wgo_omed_endoscope_disinfection pdf 7 HEAS 02 2004 2004 8 0224007 2005 9 Alvarado CJ Riechelderfer M APIC guideline for infection prevention and control in 28 flexible endoscopy Am J Infect Control 2000 28 138 155 10 SGNA Practice Committee 2005 2006 SGNA Position Statement Reprocessing of Water bottles
34. 175 CD
35. 1995 1996 1998 1CT 3 3
36. au 5 30 5 19 2 39 4 1
37. 27 o 9 35 40C 2 105colon
38. 3 Gastroenterol Endosc 2000 42 308 313 19 Helicobacter pylori ENDOSC FORUM Digest Dis 1993 9 7 11 20 Mitchell HM Lee A Carrick J Increased incidence of Campylobacter pylori infection in gastroenterologists further evidence to support person to person transmission of C pylori Scand J Gastroenterol 1998 24 396 400 21 Centers for Disease Control and Prevention Human immunodeficiency virus infections in health care workers exposed to blood of infected patients MMWR 1987 36 285 9 22 KEIE S amp HUE ARRET FUWF FERE 878 7 TO 1994 14 52 54 23 2000 25 68 69 24 Cronmiller JR Nelson DK Salman G Jackson DK Dean RS Hsu JJ et al Antimicrobial efficacy of endoscopic disinfection procedures A controlled multifactorial investigation Gastrointest Endosc 1999 51 152 158 25 American Society for Testing and materials Standard practice for cleaning and disinfection of flexible fibe
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40. 3 8
41. 2003 18 401 403 36 Dolce P Gourdeau M April N Bernard PM Outbreak of glutaraldehyde induced 31 proctocolitis Am J Infect Control 1995 23 34 39 37 Durante L Zulty JC Israel E Powers PA Russell RG Investigation of an outbreak of bloody diarrhea association with endoscopic cleaning solution and demonstration of lesions in an animal model Am J Med 1992 92 476 480 38 Streckenbach SC Alston TA Perioral stains after ortho phthalaldehyde disinfection of echo probes Anesthesiology 2003 99 1032 39 Venticinque SG Kashyap VS O Connell RJ Chemical burn injury secondary to intraoperative transesophageal echocardiography Anesth Analg 2003 97 1260 1261 40 29 1999 16 615 618 41 Calder IM Wright LP Grimstone D Glutaraldehyde allergy in endoscopy units Lancet 1992 339 433 42 Gannon PF Bright P Campbell M O Hickey SP Burge PS Occupational asthma due to glutaraldehyde and formaldehyde in endoscopy and x ray departments Thoax 1995 50 156 159 43 EI 1994 15 50
42. 420 2406 FAX 03 5420 2407 35
43. 8 520 44 FDA cleared sterilants and high level disinfectants with general claims for processing reusable medical and dental devices http www fda gov cdrh ode germlab html 32 45 Urata M Isomoto H Murase K Wada A Yanagihara K Hirakata Y et al Comparison of the microbicidal activities of superoxidized and ozonated water in the disinfection of endoscopes J Int Med Res 2003 31 299 306 46 Coates D Comparison of sodium hypochlorite and sodium dichloroisocyanurate disinfectants neutralization by serum J Hosp Infect 1988 11 60 67 47 Coates D A comparison of sodium hypochlorite and sodium dichloroisocyanurate products J Hosp Infect 1985 6 31 40 48 49 Rutala WA Weber DJ Disinfection of endoscopes review of new chemical sterilants used for high level disinfection Infect Control Hosp Epidemiol 1999 20 69 76 50 Dolc P Gourdeau M April N Bernard PM Outbreak of glutaraldehyde induced proctocolitis Am J Infect Control 1995 23 34 39 51 Durante L Zulty JC Israel E Powers PJ Russell RG Qizilbash AH et al Investigation of an outbreak of bloody diarrhea association with endoscopic cleaning solution and demonstration of lesions in an animal model Am J Med 1992 92 476 480 52 Streckenbach SC Alston TA Perioral stains after ortho phthalaldehyde
44. disinfection of echo probes Anesthesiology 2003 99 1032 53 Spaulding EH Block SS eds Chemical Disinfection of medical and surgical materials Disinfection sterilization and preservation Lea amp Febiger 1968 517 531 54 Bronowicki JP Venard V Bott C Monhoven N Gastin I Chon L et al 33 Patient to patient transmission of Hepatitis C virus during colonoscopy N Eng J Med 1997 337 4 237 240 55 11 3 2005 409 417 56 2003 32 43 34 141 8648 4 1 17 TEL 03 5
45. roptic and video endoscopes used in the examination of the hollow viscera West Conshohoken 2000 F1518 00 30 26 Chu NS McAlister D Antonoplos PA Natural bioburden levels detected on flexible gastrointestinal Endoscopes after clinical use and manual cleaning Gastrointest Endosc 1998 48 137 142 27 2000 24 84 86 28 Alfa MJ Sitter DL In hospital evaluation of orthophthalaldehyde as high level disinfectant for flexible endoscopes J Hosp Infect 1994 26 15 26 29 Hanson PJV Gor D Jeffries DJ Collins JV Chemical inactivation of HIV on surfaces BMJ 1989 298 862 864 30 Gorman SP Scott EM Russell AD Antimicrobial activity uses and mechanism of action of glutaraldehyde J Appl Bacteriol 1980 48 161 190 31 Walsh SE Maillard J F Russell AD Ortho phthalaldehyde a possible alternative to glutaraldehyde for high level disinfection Appl Microbiol 1999 86 1039 1046 32 Ruddy M Kibbler CC Endoscopic decontamination an audit and practical review J Hosp Infect 2002 50 261 268 33 Cowan T Sterilizing solutions for heat sensitive instruments Prof Nurse 1997 3 1 55 58 34 Ayliffe GAJ Babb JR Bradley CR Sterilization of arthroscopes and laparoscopes J Hosp Infect 1992 22 265 269 35 R kk O
46. used during endoscopy Gastroenterol Nurs 2006 29 396 397 11 SGNA Standards of infection control in reprocessing of flexible gastrointestinal endoscopes Gastroenterol Nurs 2000 23 172 184 12 Society of Gastroenterology Nurses and Associates Standards for infection control and reprocessing of flexible gastrointestinal endoscopes Gastroenterol Nurs 1997 20 Suppl 1 713 13 The American Society for Gastrointestinal Endoscopy and the Society for Healthcare Epidemiology of America Multi society guideline for reprocessing flexible gastrointestinal endoscopes Am J Infect Control 2003 31 309 315 14 Honeybourne D Babb J Bowie P Brewin A Fraise A Garrard C et al British Thoracic Society guidelines on diagnostic flexible bronchoscopy Thorax 2001 56 Suppl 1 i1 i21 15 2005 2005 75 9 491 573 16 2001 6 3 51 59 17 Carr Locke DL Conn MI Fagiel DO Laing K Leung JW Mills MR et al Personal 29 protective equipment Gastrointestinal Endosc 1999 49 854 857 18
47. y forming units cfu mL 10 cfu mL 14 22 23 10 5 11 12
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