アジプレンL325
Contents
1. PRTR 1 TDI MDD PRTR 22 4 21 I 338 32. 5 6
3. 2 19 02 L325 s e 3 arm CAS 1 3 1 0 3 2214 3 0 18 2 TDD
4. 11 1 3 LD50 3332mg kg 4 1 LD50 9 900 mg kg 1 3 LD50 10210 mg kg CERI 97 20 1998 19360 mg kg CERI 97 20 1998 10000mg kg EHC 75 1987 LD50 10000mg kg 4 1 LD50 gt 10 000 mg kg CERI 2000 48 2001
5. 1 3 4 1 1 3 CERI 97 20 1998 EHC 75 1987
6. 90 5 10 0 2 2 7 8
7. 1 2A 1 1 3 CERI 97 20 1998 EHC 75 1987 DFGOT vol 20 2005 ACGIH 7th 2004 9 19 02 L325 2005 1 1 4 1 1 3 CERI 97 20 1998 EHC 75 1
8. 1 2 1 1 3 CERI 97 20 1998 EHC 75 1987 immediate reaction suggestive of pain lachrymation swelling of the eyelids a conjunctival reaction and mild damage to the cornea CERI 97 20 1998 NTP TR251 1986 EHC 75 1987 DFGOT vol20 2005 ACGIH 7th 2004 2A 2B 2A 4 1 RTECS 2005 Severe
9. 10 2 8 0 005ppm TDD 0 005ppm TDI 0 02ppm TD1 ACGIH TLVs TWA 0 005ppm TD 2 6 19 02 L325 0
10. 1 4 1 2 2003 CERI 2000 48 2001 1 1 1 3 EHC 75 1987
11. 8 4 19 02 L325
12. eC 9 pH 200C 1 1 03 1 15 4 20 10 2 a 7 19 02 L325
13. CERI 97 20 1998 2001 1 2 1 2 4 1 11 19 02 L325 1 3 4 1 12
14. 1 1 3 2 1 4 1 6 5 1 91 5 1 1 1 1 3 2 1 4 1 6 5 1 1 91 5 1 1 3 2 1 2 17 19 02 L325 4 1
15. 1 3 LC50 4 0 099mg L CERI 97 20 1998 0 355mg L CERI 97 20 1998 0 34mg L EHC 75 1987 0 355mg L EHC 75 1987 LC50 4 26ppm 4 1 67Pa 25 CERI 97 20 1998 660ppm LC50 90 ppm 1 4 1 LC50 1 0 051mg L 2 2003 LC50 4 0 026 mg L 2 4 ppm 2 1 x 10 3 Pa 25 C 20 ppm 90
16. 1 3 96 LC50 0 153mg L CERI NITE 2006 1 4 1 96 LC50 1 2mg L CERI 2002 0 121mg L PHYSPROP Database 2005 1 1 3 1 log Kow 3 74 PHYSPROP Database 2005 BOD 0 CERI 1997 1 4 1
17. 1A 1 3 1A 2 4 1 1A 6 5 91 5 1 8 5 2 0 3 0 1 1 5 1 1A 1B 1C 91 5 1 1 3 1A 2A 2 4 1 1A 1 6 5 91 5 15 19 02 L325
18. 91 5 1 0 1 1 1 3 2 4 1 6 5 91 5 1 3 2 4 1 6 5 91 5 0 1 1 1 2 98 2 1 3 2 2 16 19 02 L325 4 1
19. 02 L325 2009 7 31 1 L325 Chemtura USA Corporation 199 Benson Road Middlebury CT 06749 USA 1 6 2 TEL 03 5219 2187 FAX 03 5219 2196 Email http www tokyozairyo cojp 2 GHS GHS 1 1A 1 1 1 2 1 19 02 L325
20. 6 5 91 5 2 0 1 2 1 3 2 98 1 3 2 4 1 6 5 91 5 1 3 2 4 1 6 5 91 5
21. MSDS ADIPRENEL325 MSDS Revision No 1 2 2006 12 RTECS 2005 ACGIH 2001 MSDS 1 0 1 3 LD50 3332 2 4 1 LD50 9900 6 5 LD50 91 5 100 6763 1772 5000 91 5 3 B59 9996 2 4 1 LD50 oo 14 19
22. 1 1 2 2 e
23. 6 5 91 5 1 1 1 1 3 2 1 2 1 2 1 3 2 2 1 2 98 mm2 s 1 3 2 4 1 6 5 91 5 2 1 3
24. 02 L325 6 5 LD50 91 5 100 42500 5000 91 5 1 1 3 LC50 0 05 1 2 41 LC50 0 026 6 5 LG50 91 5 100 00293 0 5 1 91 5
25. 8 19 02 L325 1 1 3 DFGOT vol 20 2005 24 on the surface of the skin as well as necrosis and the formation of granulomas 1 4 undiluted TDI 80 20 was evaluated as caustic The skin was visibly healing but the changes were not completely reversible within the follow up period of 8 and 28days 1A 1C 1A 4 1 ACGIH 7th 2001
26. 1 8 5 1 6 5 2A 2 2B 0 1 1 3 1 91 5 1 1 3 1 2 4 1 6 5 91 5 1 0 1 1 1 3 2 98 1 1 3 1 2 4 1 1 6 5
27. 1 LC50 0 153 EC50 2 4 1 1 LC50 1 2 EC50 6 5 LC50 EC50 91 5 1 8 5 2 0 3 0 1 1 25 2 1 x 10 2 25 2 91 5 18 19 02 L325 1 3 1 LC50 EC50 2 4 1 1 LC50 EC50 6 5 LC50 EC50
28. 1 log Kow 2 14 CERI 2002 BOD 0 1 13 14 12 19 02 L325 1 2 15
29. 91 5 19 19
30. in vivo in vivo 4 1 in vivo 1 3 AGCGIH 2001 A4 IARG71 1999 2B 2004 2B IARC 2 4 1 4 1 1 3 IRIS 1995 10 19 02 L325
31. 8 5 19 02 L325 10
32. 298 9 26471 62 5 1 338 405 4 1 5 0 4 119 8 0 18 2 5124 30 1 447 9 1 341 598 PRTR 20 11 21 22 4 1 23 4 1 21 338 341 CAS 91 5 7 820 4 3 19 02 L325
33. 41 57 2 18 2 9 TDI MDI 18 TDI MDD 1 4 2 TDD 4 4 2 7 1 13 19 02 L325 16 1 10 11 12 2005 TLV ACGIH 2000 2006 IARC71 1999 ICSC J 1995 DFGOT vol 20 2004 GHS 2006 2006 GHS
34. 987 DFGOT vol 20 2005 ACGIH 7th 2004 2005 1 1 CERI 97 20 1998 EHC 75 1987 DFGOT vol 20 2005 EHC 75 1987 DFGOT vol 20 2005 ACGIH 7th 2004 2005 2 ACGIH TLV 2005 SEN 1 4 1 ACGIH 7th 2001 2 3 1 Ames 1 3 in vivo
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