Microarray Data Analysis Tool Ver3.0 Manual
Contents
1. 000 0000000 00000000000 0000000000 2000 0000000 00000 0 0 0000 0000000 00 0 0000000 GenMAPP Pathway List O 0 0000000 Pvaluef O0 00 0000000000 000 000 0 0 0 00 0 0 0 00 00000 0000 00000000000000000000000000000000000000000 IGO Term List 00 0 00 0 D D 00000 000 000000 00 00 0 00 0 0 0 00 0 0 0 0 00 0 00 0 0 000 000000000 00 0000 0000000000000 OGene Ontology 0000 C320 000000 Bats Palmar F Hs kuka ZIT IEE GO Samples cC le Ha Corertsd 011 11 fe Hs TEsue specrg Copyright C Filgen Inc All Rights Reserved 40 Microarray Data Analysis Tool Ver3 0 GenMAPP Pathway List GenMAPP Pathway Browser O IILI 000000 0 000000 Nara 000 000 0 0 0 00 00 000 000 00000000 000000 000 000 00 0 Systeri 0 0 0 00000 00000000 0 OOOO 00000 000 00 00000 U Hen HM APP Fathma Dect ERES 374 Nu Ghee Hs Ieee rei a arcadia EE SEG 1 525 EA SE He Earp 0 rr rarmrirr art 1 251 1518 SEES EMEGDODDOGTET244 Hz Dot bled Hs Proteine 14 E 0 000299 EMSGDODDOCITI OE EH SION EHSCGODDO D ESSE Hs Z0 X2. Ontology Browser 0 TermListt 0 0 00000000000000000000000000 0000 OOKO 0000 00 010000000000000000000000000000000000000 0 0000 0 0 00 0000 lI Copyright Filgen Inc All Rights Reserved 35 Microarray Data Analysis Tool Ver3 0 0 0 0 0000 000000000000 00000 GO Term 0000000000 00600 00 0000 00 0 0 0 Ontology OO 000 00 0 00 0 0 0060 000 0 0 0 00 000000 1 Changed Genes Filter Options 000 00 0 00 0 0 0 0 0 00000 eor 000000000000000000000000000 000 000 00 0 l 2 Total Genes UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUN 0000 UUUUUUUUUUUUUO 3 Zscore Changed Genes Total Genes O Changed Gers OO 000 LC o Ho BB B D EB 0000 00000000 HOUUUUUUUUUUUDUUUUUUUUUDUUUUUUUUUDUUUUUUUUUUU UU 00 000 00000 HI E 00 000 000 0000 00000 0 4 P value Changed Genes Total Genes 0 0 0 0 0 LChanged Genes Total Genes 0 0000 0 GO TemmD p B U L 00000000000000000000000000000000000000000000000 Total Genes 002 5 000000000 00000000000 0000000000000 000 0 U eoremr 25 UH BLU DE 0000000
3. Database 0 0000000 000 00000 000 0060 000 00000 berti 0 00 00 0 00060 0 0 oU 0 00000 0 8 00000 000000 00000 0 0 000 000 00 0 0 I 00000 0 0 0 Pathway JJI 00000 0000 00000 0000 00 0000 Stanford 1101000000000 00000000000 LICluster and TreeView 000 0 0 ag 0 00 0000000000000 UU Ensenbl RefSeq Gene Ontology 1L DL E HL HB 000000000 000 00 0 0 0 00000 00 e Enserbl RefSeq Gene symbol 00000 00 00 00 0 0 0 0 0 B 00 0 00 0 00000 0 e 1 e 100010000 0 uman Mouse Rat O Apoptosis Cancer Cycle Cytoking Common Diseases JExtracellular Matrix and Adhesion Molecules INeuroscience_ Signal Transduction Stem Cell Toxicology and Drug Metabolism etc RatioQ Cutoff UUUUUUUUUUUUUUUUUUOUUUU U uguggugupuluia2ugumuuususuududduliatttderrtt tututititulululutut upduiiulerrp 0000 0 00 0 0 0 00 00 0 00 0 0000 5 0 0 00 0000 0000 00 0 0 0 0 00 0 0 0 0 0 i uuu Jiu UU UU HOU der OU 0000 000 U UU 00 000 0000 0 0 000 000 000 0005 00000 00000 lI 0 000 0 000 0 0 0 00 0 000 0 00 0 00 0 0 00 0 IUUUUUUUUUUUUUUUUUUU U Gene Ontology GO Slirr GenMA PP Pathway 1 O E E E U Gene Ontology GO Slin GenMAPP Pathway 1 JO Hu 0 HB Bg a d d B 7 BL L upggaiiuiituuui 0 000 00 0 00 0005 UHOUOUUUUUUUUUUUUUUUUUUOU D 0 0000000 0 0 0 0 00 0 0
4. 00000000 P value FDR Filter Options pg B 0 0000 0 U Uii dut U 00 0500 00000000 00 00000 Copyright Filgen Inc All Rights Reserved ITT SET gs cz BEST DTI QU Tu Boer 1 ET ea 1 Dub EE ane 187896 CTE TET THE 122582 n aea EO 355853 ITERATE PIEH 1 DOXEGOLIDREDMIB DI mz mer ll on 0 Ob a Te 0 OA MTA 0 DRET TSE iro D d Lex Dine oops 11 p REL Esp pre SRT Cae 4112161 CSOT d Dia EE AST 0 Microarray Data Analysis Tool Ver3 0 000000000 Gene Ontology O Gene Ontology Gene Ontology co 00 OOH 0 D Bu 0000 00 B 0 BL 00000 00 0 0 00 0 00000 0000 0 0 0 Lroicular functioni biological process cellular component O0 0 0 OOO 0 00000 D 000 000 0000 0 0 0 0 00 0 00000 0000 000000 000000 000000 Apoptosis 0 0000 00000000 0 00000 0 0000000000000000000000000000000000000000 0 orem 0 0 0 0000 0 0 0000000000 0000 0000000000000 000000000 00000 0000000000 Bug 00 0000 60 00000 000 0 0000 0 00 0 L D 00000 000 00000 00000 00000000000 6900000000 0000000000000 Gene Ontology D U 000
5. LIETA amen LED LCD Ai ET TEES i mu 29 X CREME Anz 9 mue afin 11899 In s rii Dew LTEN 2 Tm EON mpu qus Lah mme 1 1 EXER TS AFT 1 1 5522 11774 PET F m 1 poke MSS iE LEX C Oe DEFA eee 4 lp y 00000 Ratio 0 0000000 Signal OOO 00 000000000 00 000 00 30000000 CIN intensity Per Array Normalized intensity 0 Signal 0 0000 000000000000 0000000000000000000000000000000092600 0 00000000000 Sold 00000000000000000000000 3000000000000000000 00000000000000000000000000000 Copyright C Filgen Inc All Rights Reserved 14 Microarray Data Analysis Tool Ver3 0 0 0000 00010 UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUO O10 B BEL EL EL B 7B D D UU D HU o 0009 0000000000 OU UUUUU LU D UB 00000 0000000000000000 00000 n 0000000000000000 00000000 0000000000000000 00000000 Raw intensity mean fest _ Raw intensity mean ontrol Raw intensity mean intensity U U U Background mean test _ BS Background mean intensity O U U Net intensity mean est _ Net intensity mean Raw i
6. 0 0 0 0 00 00 00 00000 0 000 0000 000000 200 00000 0 00000 0 OU 000 0 000 0000 00 00000 000 000 00060 Ratio 200000000000000 00000 10 00000 00000 0000 0 0 l 10000 00000 000 000 0 0000 0000 0 00 000000 20000000 0000000 0 00000000000 0000000000 1000 Raion 20 UUUUUUUUUUUUUUUUUUUUUUU UUUUUUUUUUUUUUUUUUUUUUUUUUUU U UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUU dod UUUUUUUUUUUUUUUUUUUU 1000000000000000000000000 0000000 2000000000000000000000000000000000000 0 0 0000000000000000000000 20000 0000 0 0 0 00000 000000000 00000 L uuu ilulululiutiiiulL Li 0 uui glll gl di lll LLL 10000 00 00 00 0 000 0 0 000 0000 00 2000 Dp 0 000 000 000 0000 0000 0000 1000 Ratio 2 UUUUUUUUUUUUUUUUUUUUUUN 200000000000000000000 00000 uU uui D LU DD rpg Bgpi uiii DLL DDD 10000 00 00 00 0 000 0 0 000 0000 2000 Mel 0 00000 0 000 000 00000 000 0 1000 Raio 2 uguiuiliullili i oU DL OU EE DEO CODE COLO D UO 000 0005 uU UUUUUUUUUUUUUUUUUUUUUUUUOUUUUUUUUUUU 000 0 0 10000000 00 000 0 0000 UUUUUUU
7. 0 00 0000 000 0000 00 0 0 00 00000 0 0000 00000 0000 000 0 00 000 00000 0000 0 0 0 00 000 0 000 000 HUHUUUUUUUUUUO 977 BH Edi sik 7 Gene Ones CO fih Copyright C Filgen Inc All Rights Reserved 5 Microarray Data Analysis Tool Ver3 0 10000000 DOO 00000 006 oo 000000 0 0 CC 00 0 0000 0020000000000 00 000 D OD U 0 0000 D gored celis 00000 0000 000 000 0000000 0000000000000000 300 L UD uult nnnnn I 5 1 1 m i ii Rasa prira Huren T Canal B m ipod p Ir KASS 1 i TD Win Pees ete ae MCE 03 o ss SAC tonus ee MITE en f 592 anan JHON ESE aaae a es PRCT Ex a E jiza meo PRQ hi i iE Hira
8. 00000000 0 0 1 0000000 0 069000 0 91000 000 000 0000 5 TrevViewCustet 0 0 HOUUGUUUOUOUUUUUUUUO err 400000000 0 TreeView 0 0 0000 049000 CD HUOUUUUUO 000000000000 0000 000000000 uguuilillilibiililliililli 0000000000 00 060000000000 0000 00000000 000000 000 0 00000000000 gute and Trevi 000 00000 0000 LI Copyright Filgen Inc All Rights Reserved 46 Microarray Data Analysis Tool Ver3 0 0000000 Filter Options 00000 0000000 Excel 0 00 puq Tebow i TO D U U D UO V O UU 00 000 00000000 A100 0 0 Excell D 00 O Fold Change OO O 00 0000 0 0 00000 0 0 00 0000000000 0 0000000000000000000000000000000000000000 0 0 UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUU 0 Keyword TI 0 0 0 0001 0 00 00000 0 0 000000 0 0 0 00 180 0 0 0 0 0 0 0 INormalized intensity mean 0 00 00 0 20000000000 0 OOOO00 00000 19260 0 0 0 01 0 0 INormalized intensity mean ftatioH D 00 00240 0 000 0050 0 00000000000 19 Ignored cals Ignored cells 0 0 0 000000 O 00 200 0 Ratio D OCutor 0 00000000 00000000 0000 QUUUU UU UU 0000 0000000001 OOO EL 00000000 Filter Options O0 OOO 0 0 00 0 0 0 1 10000000000 Du Filter Optins O 0 0 FE Fi
9. 0 0 000 000 0 0 0 0 000 00 0 0 00 0000 000 utt 00000 0 0 000 00 00 illu 00 0 0000 U 4 00000000000 000000000 00000000004000000000000000000000000000000000000 iulii iiiilliiillulilliltilLliuiulli 000000 U 201000000 Ratio 0 0000000000000000000000000000 Filter Options Keyword 0 0 0000000 26 1 1 000000 00000 000 0 0 0 0 00 0 000 0 0 00000 00 Array Normalization Control gena 0 0 00 6 100 000000 0 000 000 000 00 000 0000 00 000 000 0 00 0 0 0 0 0 0 00000 0 00 HO UU UU udiuiuuililillilililiiiiilbiliilul iilii 00000 00 06 DGAPDHTI B ectinm 00000 00 00 0 0 00 0 000000 00000 0 0000000000000 ilii 0 000 0 00000 U OOOO 0000 OOOO LH III Uggubgubiuili ulli LiuttL UU UUUUUUUUUUUUUU UU UU UUUUUUUUUUUUUUUUUUUUUUUUOUUUUUUUOUUOUU LU dubii uu 00 0 0 0 0 000000000 100 Per Array Normalized intensity 000 000 DL D 00 LI 2 11 Per Array Normalized intensity 00 00 000 0 0 00 0000 Copyright Filgen Inc All Rights Reserved 11 Microarray Data Analysis Tool Ver3 0 3 000000000000 uguub
10. 200009200 00000 L 000000000 20000000 0000 080 00000000000 0000 20 0000000000 Uu ULL rj UL Copyright C Filgen Inc All Rights Reserved 22 Microarray Data Analysis Tool Ver3 0 uUBguiuiu uu UUUUUUUUUUUU UU UUUUUUUUUUUUUO UU uui Up OB UB LULULU LU UE EE UI C UUUUUUUUUU 00000 2000 0000 00000 0 0 0 0 0000 00 Ratio 200000000000000 00000 UUUUUUUU UUUUUUOUUUUUUUUUUUUUUUUU ub uuu uuu Lt 110000000000 0000 00000 00000 HU 0000 00 0 00 UUUUUUUUUUUUUUUUUUUUUU 0 00 000000 2000000000000000000000000000000000000 1000 20 UUUUUUUUUUUUUUUUUUUOUUUU UU UU Ut UE LULU ESD 000900 uU UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUOUUUOUUUUUUUUUO UUUUUUUUUUUUUUUUUUUU UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUOUUUOUU UUUUUUUUOUUU 000009009 2000000000000000000000000000000000000 0000000000 00000 00000 0 00 00000 20 0 000000000 00000 00 000 L HUOUUUUUU UU CCEC O E GEO O A U GU OE DA uU UUUUUUUUUUUUUUUUUUUUUUUUUOUUUUUUUUUUU UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUOUUUOUU 00000000 0 0 2000 50000 00000 0 0 0 0 00 0 0 00000000000 2 20000000000000000000 00000 I uU UUUUUUUUUUUUUUUUUUUUUUUUUUUUOUUUUU up gui uu 20000 00 000 0000 0 0 0000 00000000000 Ratio 2 uguguuiuiullilili IIT
11. DO 00 HI E Uu wuuiilulliululil ilL L uU UUUUUUUUUUUUUUUUUUUUUUUUOUUUUUUUUUUU UUUUUUUUUUUUUUUUUUUUUUUUUUOUUUUUUUUUUUUUUUUUUUOUUUUUUU U UUUUUUUU 2000 09 0 00000 0 0 0 0 00 0 000000000 20000000 080 0000000000000 2000 0000 00000 0 0000 0000 Copyright Filgen Inc All Rights Reserved 23 Microarray Data Analysis Tool Ver3 0 0 0 0 00 0 000 00 0 0 0 0 00000 U SARA EEC OST AH OO A EER E C GAT D BEAT S PFE Wc 9 ite _ RRC SER A A TC RFE LTRS rae cd aa s B E E C FIRB GERA LES RUA SERB ZB Cc C LSS 0000 0 0 00 0 00 000 000 0 00000 D SBE J A 1 Copyright C Filgen Inc All Rights Reserved 24 ADDER CORALINE TB TRAE TRA leas le pc fae 2 9 b uama Abe A on SL Y Ing SPS TERP 9 ww FIFA aB PATOSE ER poco Ho dicbv TAPER Ape A Te Pi L 2 TA EB et PAID mods
12. EEE ZHE gt 25 eds mom D 0 28 J HEED 207921087 k D ee pai EA E srr WITT D RT SEE I E WEE OMEN RS D OHA PHS AEH RN Ea Dn be agr fe I ES ai nian i 0 os HETE qp TENERA n x E lt 1 2 UU 3 4 UU 00 0000 0000000000 t _ gt gt 00000 0000 2 Copyright C Filgen Inc All Rights Reserved 9 Microarray Data Analysis Tool Ver3 0 Ll L 06001 Sigal 000000000 00000000000000000000000000000000000 o 0000 00000 60 0 000 0 0 0 0 0 0 0 0 000 900000000 00000000 0 0000000000000 0000000 5 0 68000000000 0000000 0 02068 0000000000000 00000000 HOUUUUOUU 00006 000000000 000000000000 000 0000 0 Lptalvs 000 10 00000000000000 SEBS re Jee CCS Op Array Human OpArray Human Op Array Human Op Array Human gt U U UU 0 LExperiment n
13. LAIT TF E VM SSS n i TTE 0080 Fi Tharati Ji 00000 0 L Scatter Plot 0100000000 UID UU 00 0 0 0 UL LL 0 Sign 000000000 00000000000 00000000000000000000000000000000001000000000000000000 XU U YO 00000 0 0 000 00 000 0000 0000 0000 0000 000000000000000000000000 00000000 00000 Sigal 000000000000000 00000 0 000000 WYO 0000000000 000000000000000000000000000 4000000 00000 utu 0000 00000 00 LL 10 Copyright Filgen Inc All Rights Reserved 29 Microarray Data Analysis Tool Ver3 0 STE S DRL T k HUOUUUUUUO Signal 000000 0000 0 0 00 0000 Scatter Plot 0 00000 000000000 000000000 0 0 00000 0 00 00000 00000 0 0 0 0 0 0000 WU UU 00 UU 00 0 000 00 liil 0000000000 0000000000000 00000 0 00000 00 000000 0 0000 00 0 0 0000 0 000 000 00000 0 0000 Signal I 0000000000000000 4000000 5 0 000000000 0000000 000 0 0 000 0 0 00 0 0000 00 0 0 000 0000 0 00000 Filter Options 0 0 0 OOOO 00000 0 0 0 0 0000 0 0 0 0 00000 0 000 000 0 OSeette 0 000 000 0000 0 0 0 0 0 00 0 0 0 00006 00000 Plot window 000000 Plot window 0000 0000000 O OScatter Piot 0O 0 0 00000 000000
14. S3 5094 TEA Field1 Per Array Mormalized intensity 34 Per Gene Normalized intensity Field3 i NNNM Field4 Field5 Field Raw intensity Gancel Copyright C Filgen Inc Rights Reserved 13 Microarray Data Analysis Tool Ver3 0 O EL EE D UE II DI signal OO OOO 00000000 900 0 00000 0 0 00 00 0 0 000 0 00 0000 000 90 Radocacuator Group Ratio calculation DD D D 0 D 0 UU U 00 TTE 10000 00000 00 0 0000 000000000710000000000000000000000000000 00000 I 5 B TE es i TENE UER mz JEI TY 121 JER LEE LOT m EEE LETA e PEN ER E riesen A Qum Lisi 3 Nn nna NJ pur anx Lea i I 11 SITES nan mr UT Sang 802200 i Tu an EEG Qus asl atio Qr ek ko amem Am cmn 1 2 EE DM HEHH 311828 LE hee 01241 3 3 Og lt AFH wee ea DEF E WEHT nd mao
15. eee 203 EES asi Era Tri E 1 Eain TET Tee HHIH EHE ERO IRA L MAH MAHE MERE HS IHME HERO EHE TE i em ES TERE IMANE HEH HET OIL 1 E N Oe Te AHS AFET QURE I m Wx SR SE ia TEE EIT EHE TOUCHE FETE E muamexa LS I EBES CASES QU FET CEN EH E MENN TOL pae eT 0 EET EXE E ERU ee EPA am 2 HOES EH c 7 Ty eT D E EH ESSEN FTE E w Se IS FANNA ee ame ee SaaS Arce TM 11 dl He EAI Ee EHS ae Cb pres 4 0000000 000 Coro 00000000000 O00 10000000000000000000 00000000 000000 0 000 000 000000000000 0292000260 000000000 riter Options I 0 P 18 0 0 000 000000000000000000 000000000000000000000 P4700 0 0000000
16. 00000000 00000000 OU U GOCO G A 0 00 000 0000 0 0 0 00 0 0 06 0 00 000 000 0000 0 0 0 0000000 0 006 Zscore GOTerm 0 00 0000 0 00 00 00000 lI UB 0000 00 0 0 0 000 0 0 0 0 0 0 0 0 0000 tl P value LL L 0000000000 6o U U U D U D XU 0000 Two tailed Fisher s exact test 00000000 Changed Genes T Total Genes GOTerm 000 Go Temi 000 Changed Genes T Total 0000000 00000000 00000000 Two tailed Fisher sexacttest 20 0 00000000 000000000 00 00000000 0 00 0 000 0000 0 00 000 eoreminiuiuullbutddiuliuiultutututututuumlitduiubi ulti bpirm uitium 000 0 D 00000 P value O 0000 0 050 0 00 00000000 00 00 0 00 000 0 00 00 0 00 00 0 0 00000 Fisher 5 exact testt 20000000000000000000 000 0 0 0 0 00 0000 00 0 00 000000 00 0000 0000 Zscore 00000 B BB B H HEEL B DEB HL 00 0 0000000 Gene Ontology ELELELELELLILLLL LLL UGene Ontology t Hl 0 Hd 0 X OD 0 00 0000 G 000 0 00 HL EL UU OU OUUUUU C
17. 00 00000 000 00000 00000000 00 0 00 0000 000000000 O 000000 0 00000 00 270 00 0000000000000 00000 0900000 0090900900000 0000000 00000 0000 0 000000000 UU 00000 00000 0 00 0 000 000 0 00000 000 500 0 00000 U KeyWord 00 00000 ANDO 0 00000000 000 00 0000000000000000009000000000000000000000000000000 000000000000000000 002030 00000 00000 0000021000000000 0000000600 0000000000 00000000 000000000000 000000 00000 0000000000000 LU ULL U 0000 0000 0 0 0000000000 00000 0 00 000 000 080 0 0 0000 UI L ULL LI Copyright C Filgen Inc All Rights Reserved 18 Microarray Data Analysis Tool Ver3 0 OOOO LI LL T 000 0 00 6 0 0 0000 tibi 0 00 0000 00000 0000 000 0 00 0 0 Function 00000000 000000000000 00000 0 0000 000 000 00000 0000 UU 00 00 0000 0000 0 00000 00000 000000 0 0000000000000000000000000000000000000000000000000 0000 00 0 000 000 0 0 00 dbi 00000000000000000 UO 0000 00 00 0000 MATIN Function Apaptnsir dam Biomarkers ame en dis Cycle ARTEL Gonmon Dreset Cytokine and dimi and Achezion blo lecular ete te Meumpcienos ARTEL Simal
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19. 0 0000 000000 00 000 0 0 00 0 0 0 000000 U 000000000 0000002000000 0 0000 0000 00000 5 10 Control Ratio 20000000000 00000 0 000 0 00 0 00 000 Copyright Filgen Inc All Rights Reserved 32 Microarray Data Analysis Tool Ver3 0 000000000 00001 00000 Sign 0000 1000000000000000000000000000000000000000000 0000000000000 00000000 000000 0 000 00 29800 00 00600 0 0 00 0 00 HOUU 00 000 0 0 0 0000 00 00 000000000000 0000000000 LLL 0000000000000000000000000000000 0 0 00000 0 00 00 00 000 000 0 0 00 Normalized intensity mean fog2ratioT 00 00 0 1 10000 Per GeneNormalizedirtersity 0 00000 U U UUUUUUUUUU Student s t test uugmuuuuugusuumuH2aumuutuuumgmuauuspipuuguiutiuupitiutuiutituitututbitt 00 2 0000000000000 P vaue 0000000000000000000000000000000 P valuer np d II 0000000000000 00 GroupRatiol I UUUUUUUUUUUUUUUUUUUUUUUOUOUU 000 One Way ANOVA 20 00000000 0000000000 000000000 0000000000 50 000000 2 0000000000000000000000 Pvaluef 0 0000000000 UP vale iuuuguui
20. 0000 0000 00 GOTerm 00000 0 ID Enserrbl ID RefSeqID 0 0 0000 000 10000000000 DB Bu 0 00 00000 6 0 0 0000 000 00 00 GO Term 00000 00000000 I 0000 00 0001000000000000 100000000100 COTem I 0 00 0 0 0 0 0 0 6 600 0 00 00000 000 00000 00 000 00 0 00 L Copyright Filgen Inc All Rights Reserved 37 Microarray Data Analysis Tool Ver3 0 00000000 GO Term LL LLLLELLL LL LL LL LL 00 GOTeml 00000 ID RefSeqIDI 0 0 000000000000 00000 00 000000 j 2000000000000000000000 200000000 Ij 60 Temm D 00 0 0 0 B 00 0 000 U IUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUU OU GeneOrttdogy 000 00000 000000 GOTerm 00 0000000000000000000000 000000 5 Total Genes 2000000000000000 0 000 gii HW 00060 0 00 00000 DU 0000 00 0 Changed Genes O O 0 0 015000 0000000 00 GO Term 400000 00000000000 0000 00 000 0 0 000000 150000000000000000 ULL 00000 LI Z score LI LLLI GOTerm Changed Genesii 00000000000000000000000000000000000000 0 0000000000000000000000000000000 GO Term Changed Total Genes 0 000 GO 000 GO O Changed Genes Total Genes 0 0 0000400000
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22. 0 00 0 0 0 00 000 0 00 0 00 00 000 0 0 0 00000 Z score LI LLLI Gene Ontology DO 00 00 0 UU UU 0 U Gene Ontology D 000 CP 38 D D DI D 0060 P value Ll LL 0 Gene Ontology O0 0 0 00 0 0 0 00 00 Gene Ontology P 380000 000 GenMAPP Pathway JGenMAPP Pathway 0000000 LU Copyright Filgen Inc All Rights Reserved 41 Microarray Data Analysis Tool Ver3 0 000000000 external Filter External Filter LLLI uuu di UU UU 0000 00 00600 00000 00 000 00000 000 000 2000000000 00000 III 0000000000 20 0000000000 00000000 0 00000 EZ BET 5 0ligo ID 243 A olieo id zT Hp T SE Sa 12 PF 5000000060237 PRKWNKI 1899 550033096 1232026786 460769023 53558777 200013401 ENSG UDODUSO749 NP 079050 Tm 11 5 823921875 1598396161 53897436 60912088 H300018481 5000000061273 HDACTA 21544 28 15 25 294765625 217350446 47047619 52579155 H300016373 ENSG00000061939 ACKI HUMAN 10558 14 15 1 316167411 647247768 5087093 60010999 H300011438 50900000062194 NP D75064 32435 42 13 8 446553571 604506606 56014652 58893773 200007926 ENSG00000067369 35328 46 4 12 1210770018 2256772321 568556777 60212454 200006046 ENSG00000067829 IDH3G 3454 45 3 18 438323661 1120276786 4679120
23. C Tee GEXHT 2 C Cancel Ignored cells Copyright C Filgen Inc All Rights Reserved 44 Microarray Data Analysis Tool Ver3 0 000 Cluster and TreeView E E DJ D 0 Stanford 000000000 and Treeview 10 0000000000000 0000000000000 00000 0 Data Analysis Tool O O 00 00000000 6590000000000 000000000000000000000000000000000000000000000000 UCluster TreeView 00000 000 0 00000 Cluster and TreeView 1 0 0 00000 00 00 0 0 0000 DU http rana Ibl gov EisenSoftware htm Top e Eisen Lab Ir our eel iem of charge dere ohe rm Cho iior seer our m ere fore i k oniam airs kim af fea Fama pee cee ES Eerbetey Pieters Lab Fir on hra boobies 4 nd sper iret plese coctec Lew Troni er zog Corp zr mi 5 imine Egibar Heru ea Lo Ragu a an f Prom and in imad ip age mri tp reas Legit required 59 Fitur Dada ara usa Fin ET Birao 2 mima 1 2 Top softward
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25. The Human V3 AROS design is based on the Ensembl human 13 31 database This genelist provides a simplified version of annotation based on the Ensembl human 13 31 database http www enserrbl org Ensembl transcript id For common or partial common oligo types one transcript is chosen randomly as a representative transcript The id of this reoresentative transcript is the representative transcript id As the individual oligo type represent only one transcript this transcript is the reoresentative transcript oligo exon or transcript Oligo is fully located in an exon Oligo spans more than exon C Oligo represents all transcripts of an Ensembl gene oligo type P Oligo represents a subset of transcripts of an Ensembl gene Oligo represents one transcript of an Ensembl gene M Oligo represents multiple Ensembl genes gene syrrbol Gene symbol approved by HUGO Gene Nomenclature Committee description Ensembl Description based on gene RefSeq accession from NCBI Reference Sequence collection which is mapped to the human genome by Ensembl For further information on RefSegs please refer to http www ncbi nlmnih gov RefSeq Description based on gene Accession from EMBL and GenBank LocusLinkID homolog mouse EnsemblGenelD homolog rat EnsemblGenelD GO biological process GO molecular function GO cell location ChromosomeName Start Position bp End Position bp Middle Position bp RefSeq description RefSeq
26. 00 0 0 U 0000000000 0000 000 0 0 0 0000 DD 0 00000 HOUUUUUU ugugggulllliliid 00 00 0 00 0 0 00 0 00 0000 0 0000 000 LU UD D DU 000 9500000000 Windows Xp Windows 2000 00000000000 00000 0 00000 98 0 060 00000 000000001000 UUUUUUUUUUUUUUUUUUUUOUU 000009 000090000000000 0000 0000 i illii 00000 0000 000 0000 0 0 0 00 0 00000000 0 0000 00 0 0 DU 00 0000 00 00 00 000 000 0 00 0 0 uuu Li DO B E 00000 uoa uiii UU 0 0 0000 0 0 00 0 00 0 0 000 0 Copyright Filgen Inc All Rights Reserved 2 Microarray Data Analysis Tool Ver3 0 000000000000 BEN TP 00000000 90000000 000000 10 1 mmm 0000000000000 000000 0 UMcroarrayDataAnalysisTool II 00 D D 000000000 UUUUUUUUUUUUOUUUUUUUUUUUUUUUUOUUUU 062 OO 0 0000000000000 O E U 00 090000 000000000000 00000000 000000 Microarray Data Analysis Tool Ver3 i REP BANA PIED Qm O 27 De pons m E A 4x EI TAT 1028 200742594 1038 dam E 24 2105 200751291 11 5n L 7rd zal 2007712231 1045 2007 1241 1066 Push cu SKB Hut ATAZA 4517 2780 KE
27. 000 000 00 000 0 000 0 00 0 0 0 0 0 0 00 0 0 0 0 00 00000 0 0000000000000 0 0 00 00000 00000 0 0006900 00 ggg m ad 000 000 0 UUUUUUUUUUUUUUUUUUUUUUUOUUUOUU 00690000 000000000000 000000000 0000 EE Pathusze Hs Respons Pathe Gras Z sora 2939 nz ont bred 20070308 celluler procecz MED DHE procesz GenMAFFP functor Gank APP phere me wal MAFF Hs BCE Inhrior peta ay Phar rski Hs Hz Blood Cascada takun moision n cardiac alk Hz Exerc me Hs Activation Class pd Campe meri and Da Hx Culnkinaz Ee iai 8144 20 ABO 510 8 125 14 145 4T F Pu Hz iuo Hz inaradek Hz Smnmath Hs Str ated nanc le contrabtion Hz GO piks Helge Jos wo oma wog sy gam cd function fortu Done red 20041 111 He Tissue apie 20080771 Gene Ontology Browser 0 0 GenMAPP Pathway 7 00 0 0 0 00000 0 000000000000000000 OOOOO0000 0000000000000 Pathway 0 0 0 ILICortributed T Biological process
28. 388 A DER TERES MER HbR FE STDERR Ca ae aha O TATO AITA TA d Tau FATON AITA TRE d Traer 7 195021 Sm eta C d Kb der C EELE d Ab TRF C ELR OD C ELR OD CAA C JELE d C Teta ism C C EELE 9 um HESS lt Signal 0000000 Fold change 0 0000 0 0000000 0 00 00000000 000 00000000000 Ratio 00000000000 Copyright Filgen Inc All Rights Reserved 20 Microarray Data Analysis Tool Ver3 0 0 0 0000 000 0 U DE UN UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUOUUUUUUUUUUUUUUOUUOUUUUUU Gar 000000000000000000000000000000000000000000000000000000 00000 00000 00 0 0 000 ES TS 0 00 0 0 0000 00 0 liil 0 000 0 i 00000 0 0000 00 00 0000 UUUUUUUUUUUUUUUUUU 00 0 G U 0 00000 0 U UEG OCU UO AGUL Reet O00 0 00000000000000000000000000000 00000 0000000000000000000 00000000 00000000 00000000 UFilter option 00000 U OO O O DO e e E S OE EEL UH UOUU uguuiuiiuLiulltiliiltLL 0 UUUUUUUUUUUUUUUUUUUUU 000000 20000000 0 00000 0 000 L 000000000000000 0000 00 0 00 0 00000 0 0 000 0 0 0000 0700 000000000 00000000000000000000000000000000000 0 000000000000 000 0000 00000
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52. Filg geng biochip amp nanofilm technologies Microarray Data Analysis Tool Manual Ver3 0 2008 3 JU 000000000000000000 0 2000000 0000000000000000000 00000000 0000000000000000000000000000000000000 00000000000 0000000 00000000 000 00 000000000000 00000 0 00000 00000 00 00 00 00000 0000000000000 0000 0000 000 0000 00000 000 00 000000000 0 00000 0 0 0 0 00 00000 0 0 60 0000 456 0032 000 0000 D HH 1500 1 Td 0521 624 4388 9 00 17 00 Fax 052 624 4389 E Mail biosupport filgen j p http w w w filgen jp Copyright C Filgen Inc All Rights Reserved Microarray Data Analysis Tool Ver3 0 1 00000000 2 2 00000000000 P 3 3 000000000 00000 PA 17 4 UU U Filter option 181 28 5 00000000 OScatter 29 32 6 00000 P 33 34 7 100000000 Gene Ontology O P 35 38 8 000000000 Pathway P 39 41 9 Filter 0 0 42 43 10 000000000 0000000000000 UU 44 11 100000000 UCluster and Treeview L 000000 P 45 46 12 471 48 13 00 P 49 Copyright C Filgen Inc All Rights Reserved 1 Microarray Data Analysis Tool Ver3 0
53. ID lt 15 IE 1 Tes Dmm Totes lee Fade D Tn gt 8 ET TEX THES mm si nim pe one Enid Xn aiti fT FHAD a i ka kn capa ior s 251 1250 PaO aE Iun i ierra of pik D EET adi Seed I NERIS MEC aas Loris caapi EE ci ogi ENRETA we 2 HF pecia mier 0 rm aT E1 E Iz 12 im T FETT AF TU idis Qc Fa ra ERE ER TIE MH EC COE TICO EHSAN rte cada Tense runi ramen wor EET aE m Wd cr Wa 2171 E ot tener N ORES PASO EHS jari 1 fi eal ruga 1 1 p Yd uncia kon GENES eS om lin exi EHCAE T Ban axi MHI h 000 0 00 0 0 00000 0000000000000 000000000000000000000000000000000000 corem 000000000000 0000000000000 2000 00000000000 000 00000 ID intensity
54. Microarray Data Analysis Tool Ver3 0 OOOOOO OUUM m 0 0000000000000000000 000000000 DDGroup Ratio calculation 000000000 000 calculation 0 000 0000000000000 000000000000000000000 00000000000 0000 0 00 000000000000 00 00000 00000000000 0 000 000000000 000 00000000000000000000000000000 nx 000000000 0000000 Per Array Normalization O uer EOF ART 00000000000000000000000 pmi pip m buuuutuutuiliiuiut 0000 00000 00000000000000 0000000000000 Age dau L HE kk ALi D PR L ui 17 1 Signal ODO 0 0000 2000 dani dd Ratio calculatiofM 0 0000 000000000000 3 00 GRatiog O 000000 U Group Ratio T 000000000000000000000000 Ratio 0 0 0000 00 000000000000000000 00000000000000000000000000000 Gag Fal MERE MUSE iS chi 000000000000000000000000 Ratio TE T Group Ration HD 00000000 0000 Ratio 00 Group Ratio 00 00 00000000 UUUUUUUUU epmmuuubuuguuuiuugugsimiuuuuuututiuuiutuiututuiuilu utu litur utu 0000000000000 0000000000 00 0000 0 0 0 0 me GeneNomalized intensity 10 0 00000 0000 000 0000 000000 0 6000 00 000 0 0010 060 0 0 60 0 0 0 0 0000000 000000000 OOO 0000 00000000 Ratio O Ratio OOO DU 000 00 0 0 00 00 00000 0
55. Ratio line Ratio OOO OO 000000 000000 00000000000 000 00 00000000000 000 0 Ratio 0 0 0000 00 000 00000 00 0 0 0 0 0 000 0 000000000 Plot Scatter Plot O 000 000 O 0000000 00000 0 0 0 0 0 00 0000 raph Scatter Plt 000000000000000000 0000000000000 7 Scatter Plt 7 000000000000 000000000m0000000 00000 00000000 0 0000000000000 OScatter Plot options OOO 0000 0 UUUUUUUUUOWUUUUUUUUUUUUO Copyright C Filgen Inc All Rights Reserved 31 Microarray Data Analysis Tool Ver3 0 Scatter Plot Scatter IUUUUUUUUUUUUUUUUUUUUUUU U IUUUUUUUUUUUUUUUUUUUU Scatter Plot 0 Scatter Plot 0 0 0000 000000 0000 000 Scatter Plot 000 BMP UUUUUUUUUU 00000 Filter Options O0 0 0 0000 0000000000000 000 0000 0000000 0 Scatter Plot 0 DD 00000000 00000000000 Scatter rmn nm u U 00000 000 00 00 00 00 0 0 60 0 000 000000000 Ug 0 00 000 000 0 0 00 00 0 0 00 0006 No 000 D D 00000 00000000 Uu 00000 00 0 0 006 OO UU 000 000 UU 0 00 0000 00 00 0000 0 0 0 0 0 Scatter LU UL o Filter Options T OOO 0000 00000 iit HUUUUUU 9 000000000000 000 Scatter plot
56. Template zymbezis of G _ idrawppiaan register activity d rapier acimitu irreporier camponent esca PEPE T J LL 1 B i eC X JE i e ay C Copyright C Filgen Inc All Rights Reserved 36 Microarray Data Analysis Tool Ver3 0 GO Term List 0 GO P value 0000000000000 00 0 000 000000000000000000000000 00 0 00 00 0 000 00 000 00 0 00000 0 0 0 00 0 0 0 0 0 00 0000 00 00 00000 GO Term List 0 GO Slim List 0 J JETS ena pee eed s REFER Pain Tec F cellar component eT ap Dinka cal process ET ETAT LU U O O Gene Ontology O U U UU UUUU Gene Ontology GOSlim 0 0 0 00 0 00 00 0000 00 0 000 D 6ene Ortolooy 0000 D UU GO Term List O0 0 00 0 0 Temi function pellular component biological process O DU U U 0000000000000000 00 060 Sim 0 0 0 00 00 0 00000 00 0 0 00 0 00000 00 000000000 0000 0000 12PH ES 5 io B 0 li Tam ET EL IT EIL um axe 10 za dT SEA M
57. Transduction SL Dal dieis and PFarnacnlogs dare als Aon ol sas ix ipo pig Damara Sana Aon pleas Palsy Apo pi req E amp Toxickp Finder ipapinziz Dirag Responses do Biomarkers Bresl Cancer Eomarkers Biomarkers e reer ular Dense Biomarkers ell w UD BOE 0 0 0 0 0 00000 06 000000000 00 00 00 Chromosome 00000 Da D 000000000 00000000000000000000000000000000 5 0 0 00 00 0000 L 00000 LL 000 0 0 0 0 0 00 00 0 00 0 0 0 00 0000 000 00 00000 0 0 00 0000 Normalized intensity 0000 0 0 000000 00 D 0 0000 0000 D D 00 0 D 000 0 Normalized intensity mean Fates ME FF F C AND Normalized intensity mean CP C95 AND COR Normalized intensity mean est gt AND Normalized intensity mean kor gt Cf Ff AF G AND der 27 h E Op ee 2 000000000 00000000 0000 000000 intensity 000000000000000000000000000 Copyright Filgen Inc Ri
58. ame Control 00 laveling T 0 00000000000 0 Net OO 000000000 00000 000 00000 00 10 00000000000000000 0000 Ratio Fold Change 0 n 00 00000000 00000 000000000 00000000 0000000000 00000 E FZ Data Edit Low data treatment zx Met intensity mean Met intensity mean DL FEI d E dm CO DOT ECT ELT Sdn T Per Array Normalization T Per Gene Normalization C Gantral experiment Ratio calculation Copyright C Filgen Inc All Rights Reserved 10 Microarray Data Analysis Tool Ver3 0 OOOO 000000 0000 00000 000000000000 2000000000000000000000000000 Net intensity mean 0 00 000 00 0000000000000 000 000000 0000000000 000000 intensity meani 0000 0 00000 000 0 0 09003 UL UL 0000 0 0 00 0 00 UOUUgultuL Low data treatment 10 zx Met intensity mean 10 Met intensity tmean pr FORNE d E D OOS ELT dE 0 00000000000 Net intensity 0 01900 000000 0 02900 00000000 OOOO O OOOO 0000 0000000000000 0000000 00000000 0 0000000000000000000000 0000 0 0000 0 0 000 00 000 U 0000100 LU UL ULL 000 0 0 0 0 0 0 00 00 00 OU illiid 00000000 0 00000 00000 U ut 20000 0 00 00 0 0 0060 0 0 0 00 0 000 00 0000 3 0000000 00 0 00 0 0
59. chai mom Comit 18 ET mm BER SiE jui pua Tee ETT 1 IRE See SEE UO 0000000000000000000000000000000000000000000000000 0000 0 0 0 0 0 00 0090 0 00000 00000 0 UU UU 0 0 0 OU 0000000 0600000 0000000000 000 U OO 0 000000000 0000000 0000000 000 00000000 UOUUOUUUUOUU UUUUWUU 0000 0000 B 00 0 00 UU U COO 1 Field Raw intensity means test Iw Field2 Raw intensity mean Control Iw Field3 Mormalized intensity mean ratio gt Field4 Copyright C Filgen Inc All Rights Reserved 8 Microarray Data Analysis Tool Ver3 0 0 0000 0 000 00000000000900000000000000000000000000000000000000000 0 0000000000000000000000000000 000000 00000000000 s 12 000000 2 SE DEBATES 0 n ELIT UTE marc 3 1 TATED TN T eme 122707 Ene EE WEHE 1 D emm IEE io IEE IE 5 ERE TE binme Samaria E n E EtA 0 i
60. ghts Reserved 19 Microarray Data Analysis Tool Ver3 0 00000 000 000 00000 00 00000 00 0 0 000 00 Rete Group Ratio data 0 000000 0 0 0 00 0 0 DD 0 UO 0000 000 0 00 00 D BEC EE DT CT E Feldchanget 00000 00 00000 00 000 00 0000000 Raion 0 000 000 00 U URatio data OOO 000 0000 0 0 00000 00 Sorel OO 0000 Group Ratio 000 0 0 Ratio data 0 00 0000 00 0 00 0 000000000 000 00 000 000000000000 0000000 Ratio data 3 bk c LIF AMD fF OR Group Ratio data C Hik E LIF 00000000000000000000 000 FDR P value FORO 000000000 Ch ME HOUUUUWU UOU 0 0 0 000 0 00 0 0000 00 FDR 000 00000 0000 tL cE pe CE 00000 000000 0 0000 lgnoredcells OO D 0800 00000000 000 0 D CO 0 D OLEO DEDE CO T 0000 Seer OO0000010 000 Ignored cells rinm 00000 0000 0000 0 00 0 0 00 09000 0 U 0000 000 0000 000000 lenored celle Ignored cells Signa 000000000020000000000 00000 1800000000 EBT HERR TIRE C ELLER CAAT eS C ELLER TAHARI THA TBS MERCIA ORR 04
61. guililiLulttuttutuiiuiuliibtil lilii 0 000 0 6 0 00 000 0000 000 00 0 00000 00000 000 0 00 00 0000 0000 00 00000 0 0 0 0000 000 0 00 000 000 0 0 000 0 000 00 0 0 00000 0 HOODOO 0 0 000 0 0 0000 00 0000 00000000000 19920 0000 0 0 0 0000 00 0 00 00 0 HUOUUUUUOUUUUUUUUUUUUUUUUU EOD CLOUD ELE III 0 000 HOU 000 000 0000 0 00 000 00 00 0000 0 0 0 0 Wl 0000 000100000 unpaid i 00 0 00 0 000 0 UUM 000 U x 00000 00 00 000 00 0 0000 0 E 000 8 0000000000 Select 0 0 00000 0 0000 000 gt 0000000000000000000000 Ignored cells 00 0000 000 EOFs EANET 0000000000 0000 0 0000 U 00 00 0 00 0000 UU 00 0 0 00 0 000 0 0 00 00 0 0000 000 Per Array 1 OO 0000 0000000 00000000000000000000000000000000000000000000000000 00000000000000 000050 00 00000 0000000 00 0000000000000 Ratol 00000 0 000000000000000000000000000000000000000000000 0 000000 0 0 D UGroup Ratio calculation O00000 00 0 00 000 00000 0 r oij Fries SA Cae Se arme Fi FAR METTE mERL T FE Copyright Filgen Inc Rights Reserved 12
62. lter Options Search Option Joe LL itencity meari mar Hormaled intencily imaan ratu w browd cell 4 P imed HERTS Cancel Copyright C Filgen Inc All Rights Reserved 47 Microarray Data Analysis Tool Ver3 0 0200000000000 000000000000000000000000 9 000 A2 Signall OO 00000000000 0000000000000 Array Normalization Per Gene Normalization i 00 O 00000 0000 00000000 000000 00000 00 00000 00 0 0 0 000 00 000 000 0 000 00 00 00 000 0 0000000000 0000 Uggaubilul L Pe Array Normalization 00 0000 Medial 00 0 0 LIQuantile T O 0 00 00000 Medardi 000000000000000000000000 0000000 00000 11000 0000000000000000000000000000000000000 1000000000000 000000000000000000000000000 0 0 00 00000000000000000 000000000 0000000000000 Per Array Normalization Per Gene Norrralizatio 000000000000000000000000 0 Gene Norralzatior 0 110 0 000 UO OOD 000000 Oto 0000000000 Q3 Gene Ontology O 0 Pathway 0 0 00 0 BD 00 DI 0909508 00 0000000000000 A300 0000
63. ntensity mean Background mean Net intensity mean Net intensity mean test Net intensity mean control H Normalized intensity mean est Normalized intensity mean control n Normalized intensity mean Normalized intensity mean est control Normalized intensity mean est Normalized intensity mean Normalized intensity mean og2ratio Normalized intensity mean log2 000 MUD L E 0000 E J Js J 0 0 1 1 0000000000 00 OLH D UU Ud IBI Raw intensity mean 0 0000 intensity T 0 0 0 Background mean intensityoo 0 D Net intensity mean Raw intensity mean Background mean P value Benjarrine amp Hochberg 1 0 0 0 False Discovery Rate J 0000000000 0 D Raw intensity 0 000 0 00 000 000 0 0 0 0 000 000 D 0000000000 L Copyright Filgen Inc All Rights Reserved 15 Microarray Data Analysis Tool Ver3 0 0000000 Aon M 00000000000 00000 000 000 00000 dori 00000 0 0 00 000 i D 0 0 DO B 00 0 00 0000 0000 0010000000000 000000 000000 00 0000 00 000 0 0 00000 00000 00 090000 00000 2 2 oligo id Operon Biotechnology 1 00000 D 0 D 00 00 0 0 000000 FUUGA UOU GAE
64. opyright C Filgen Inc All Rights Reserved 38 Microarray Data Analysis Tool Ver3 0 000000000 000000 000 U Pathway Pathway D 00 D ODD 00000000000000000000000000000000000000000000 000 00 00 00000000000000000000 http www genrmapporg 0 00000 00000600 06000 OU 000000 00000000000 00000000000000 00000 000 00 0 0 0 0 0 0 00 0 000 00000 6 O 00000 E DL DL 00000 00000 ELELELELELLL 0 Pathway E I 0050000000000 4000 0000 000000000 00 E 0 ELE 00000 0 00000000 000 0 00 0 000 0 00 60 000 0 00000 U 1 Contributed J I 000 00000 0 00000 0000 0 00000 00 0 00000 00000000 0000000 LIContributed 1 00000000000 2 Ontology 0000 00 LCortrituted UUUUUUUUUUUUUUUUUOUUUUU 3 KEGG converted KEGG Kyoto Encyclopedia of Genes and Genomes Contributed O O0 000000 00 00 000000 000000 4 Tissue specifid D 000000 0000000 00000 000000 00000000 000 0 U Pathway 0 Gene Ontology 00 D 0 00 0 0 0 00 0 000 000000 O 2 000 0050 00 0000 0000 000 000 0000 0 0 0000000000 00 00 000000 00000000000 0 0000000000000000000000000000000000
65. r 2 0 2008 3 0 Filgen biochip amp nanofilm technologies Copyright C Filgen Inc All Rights Reserved 49
66. uiuillusiuliilliliB 0 000 00 0000 00 0 0 0 0 0 000 0 0 00 0 0 0000 00000 0 0000 0 00 0 00000 9 One Sarrple t test HOUOUUUUUUUUUUO HOUUUUUUUUUUUU U U P value O0 0000000 20000000000000000000 IJJ 00000 0000000 00000 000 0000 9000000000000 HU O O UUW UU OD UU UU U 00000 00 0 0 0 EE 0000 L 000 000 0000 00 000 0000 00 0 0 000 00000 0000 0 00 0 00 0 00000 0 0 00 00 000 00 0 0000 00 60 0 00 0 00000 tL 20 L E O UL UL UO D Ut O r4 H Uu UOLBILDULLIL 00000 00 0000 00 HUOUUUUUUUU 0000000 00000 0000 0000 00 BD B 0000 0 0 0 0 0 0 0 0 0 0 00 U Ignored cells OO U P value 0 OO ULU U E B B IU 0 U Ignored cells 18 000000000000 000000 0000000006060 HOUUUUUUUUUUUUUUUUUUUUUUUUUU 000 0000 0 0 0 0 0 00 0 0000 D 0000 00000 0 0 0 10000000000 FDR Benjamini and Hochbero 0O 0 0 0 Pvaluerr 00 00 00000 00 000 00000 0000000000 0000 ug umiluiliiiiiiil ilii Db OD 0 0 0 0 00 0 00 00 UU 0 0 0 0 0 O 000 00 0 0 00 0 000 0 00 0 0 0 0 0 0 0 0 0 0 0 0 00 0 00 0 000 0 0 00 0 000 0 0 0 0 00 00 E 00000000000 00 00 10 0000 0 0 00 00000 FDR False Discovery Rate 0 0 HB 00000 00 00000000 000000 0 0 0000 000000000
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