ヘパリンナトリウム製剤の自主回収（クラスI）について
Contents
1. HIT 3 22. HIT 3 2
3. 9 heparin cofactor 9 lt 95 10 090 10mL 10 59 000 50mL 10 100 000 100mL 10 1 Thomas D et al Chest 102 1578 1992 2
4. CO 3 HIT HIT 2 4 5
5. t P A 1 1 2
6. 1 1 000 lt 3 000 1 500 1 500 1 500 1 500 1 1 500 2 500 2 150 300 kg 100mL
7. d 5 6 HIT heparin indnced thrompocytopenia HIT 6 3 1 Na 150 nmL 20mL 1 20mL 3 000 p Na 200 L 20mL 1
8. P 1 1 2
9. 2 3 4 5 6 HIT heparin induced thrombocytopenia IT 4 HIT
10. 3 HIT HIT 100 7 6 heparin cofactor 59
11. 3 HIT HIT 2 8 AST GOT ALT GPTT 9
12. 3 HL 8 1 9 CCE
13. 6 7 1 2 3 4 5 2
14. Nd ET at ea eateat ea ear eat nt ase tat wat a ia a a ti ta ata a MA est na tains te A NAA aA te a i a at I oT oY oT oO NT its
15. Lee White WBAPTT 2 3 1 000 3 000 1 500 1 500 1 500 1 500 1 1 500 2 500 1 1 DIC
16. ILI 3 8 H 4 22 2 0 1 4 2 8 _ 3 8 I
17. 1 27A1X00039 TEL 06 6941 0351 4554 FAX 06 6944 6701 20 5 2 3 11 1 FDA 1H NMR CE YE 4 22 2
18. 3 8 H 5 5 000 50 000 HI
19. FF 20 5 2 2760 2765 03 3595 2436 2755 2753 03 3595 2435 4Y A gt 1 4 2 0 5 2 2 Tt C1 2 3 1 1
20. 10 000 30 000 5 5 HIT heparin 1 000 1 30 WBAP 2 3 1 20 1 5 000 10 000 4 8 3 2 4 WBAPTT 2 3 1 5 000 4 1 2 3
21. 2 3 4 5 6 9 HIT heparin induced thrombocytopenia HI 5 3 1 1 mL
22. 1 000 lt 10mg mL pH 2 lt DH 5 5 8 0 8 1 6 Lee White WBAPTT 8
23. 29 1491 1987 3 Goodman amp Gihman The Pharmacological Basis of Therapeutics Sth ed 1313 1990 Howell W H Amer J Physiol 71 553 1925 5 Brinkhouse K M et alL Amer J Physiol 125 683 1939 6 Quick A J Amer J Physiol 123 712 1938 536 8523 8 30 TEL 06 6964 2763 FAX 06 6964 2706 9 00 lt 17 30 3 1 DK 918 913A D 3 t D7G TN 2007 7 2007 7 8733834 1560 mL 200 mL 250 mL 21900AMX00581 21800AMZ10232 2007 7 2006 7 2006 7 2007
24. 5 7 1 2 CCE 3 HIT HI 100 7 5
25. 95 1 3 R 5 6
26. 7 9 000 150 mL 40C 75 6 200 mL 250 mL 25 605 37 7 HH 150 mL 3 000 20mL 20mL 10 200 mL 4 000 20mL 20mL 10 250 mLC5 000 20mL 20mL 109 30 30 30 1 Thomas D et al Chest 102 1578 1992 2 29 1491 1987 3 Goodman amp Gilman The Phnarmacol
27. 2007 7 10 2007 6 873384 10mL 50mL 61AM 2259 1971 8 1971 8 1971 8 1980 8 ER 1 cl Heparin Sodium Injection 1 DIC
28. 20 000 p Na 250 mL 20mL 1 20mL 5 000 pH 2 Na 150 mL 20mL Na 200 mL 20mL Na 250 mL 20mL pH 5 5 7 1 0 9 1 1 K
29. 400 500 20 30 mL 100 1 1 2 3 4 ndiuced thrombocytopenia HIT 4 FIIT
30. 7 2006 7 2006 7 Na 150 mL 20mL Na 200 mL 20mL Na 250 mL 20mL Heparin Sodium 150 Units mL 200 Units mL amp 250 Units mL Syringe 20mL 7Fuso for Dialysis 1 DIC 2 3
31. 0 1 4 2 8 1H NMR 0 2 5 2 0 0 2 N a 200 m L 20m L Na 250 7m 20m
32. 0 000 5 2096 20 5 2 _ _ 06 6969 1136 FAX 06 6969 3139 3 8 3 8
33. LL 10 000 10mL 50 000 50mL 100 000 100mL 08C13C 08C21N 08C25C 08C25N d 0 PP 2 5 000 5
34. ogical Basis of Therapeutics 8th ed 1313 1990 4 Howell W H Amer J Physiol 71 553 1925 5 Brinkhouse K M et al Amer Physio 125 683 1939 6 Quick A J Amer J Physiol 123 712 1938 7 8 9 536 8523 3 30 TEL 06 6964 2763 FAX 06 6964 2708 9 0017 30 3 11 DKR 912 912B 4 mm mm
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