遺伝子組換え分泌型ヒト成長ホルモン製剤
Contents
1. 8 mg 1 33mg 20 8mg 1 33mg 2 64mg 8 1 9 2 2 C C 92. GOT GPT exostosis
3. 1 2 1 Ss
4. Tmax Cmax Th AUC hr ng mL hr ng hr mL 9 1 P 3 1 87 22 2 9 0 9 590 88 CPK 8 mg A RC 5 rsame 4 1 27621 2 7 0 9 564 81 2 SD 0 12mg 8 mg 28 12mg RE 8 mg 4 mg 1 3 4 2 4
5. 0 5 kg 0 175mg kg 2 SD cm 6 5 2 3 1 25 3 3 1 3 8 0 1 8 2 1 7 14 4 4 1 5 6 1 0 9 7 0 1 9 1 RO 2 1 33mg 2 ei
6. 25 14 3 39 2 11 6 4 8 2 5 1 1
7. Tmax Cmax Ti2 AUC hr ng mL hr ng hr mL 5 4 1 0 8 41 5 11 6 2 30 0 66 287 62 12mg 4 1 1 0 43 4 12 5 2 14 0 64 288 62 6 8 mg 1 SD 1 1 33mg 2 8 1 28
8. in iMerckSerono MERCK 1 2014 11 3 872412 2013 10 2 i 12md Saizen Liquid12 mg RT 22400AMX00784000 3 2 2 8 1 2013 6 18 2013 8 3 GS 12m Q 5mL 160 3 0me
9. gt 1 1 2
10. 3 in vitro TL hGH Somatropin genetical recombination growth hormone human genetical recombination CeoHissNzezOsooS7 22 125 191 12mg 1 1 1 2 2 3 17 5 2335 1989 4 17 12 5737 1989 5 18 2 399 1990 6 17 10 4977
11. 30 112 5mg 5 6mg 2 90mg pH 5 6 6 6 0 9 1 6 C127 E gt 1 kg 0 175mg 6 7
12. 1989 7 17 12 5733 1989 o 26 30 TEL 0120 121210 FAX 03 6418 3880 Se EE U 1 1 8 1 Merck Serono S A 26 30
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