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CaseCenter 2.6 User's Guide

1. 3DHISTECH CaseCenter 2 6 User s Guide July 10 2015 CC26 UG EN Rev1 Rev 1 CaseCenter 2 6 User s Guide Contents BIVIO sacs envacvan vases cecsanaes ecruundnsesseasnssnetessematwset aticatncsevscotuiessannsoeiuetenssevasshossseusecseneeweeseacteesesuser este 4 Character Types and SVN grass saeco nce ada ia 6 Terma AAG ADDIVATI ON secs saannstneseacenthas iaia gii rallenta siepi 7 TADOU CASE ONTO erenn E RI 8 1 1 Storing and Managing Digital Slides through CaseCenter 10 LZ ACCOGNEG Ir 11 1 3 Uploading a Slide to a CaseCenter 11 2 COMIECUNS tO CISEEENTEl vivir ranieri cata nanne 13 2 1 Connecting through Pannoramic ViewWer 13 2 2 Logging in to CaseCenter through CaseViewer ii 13 2 3 Logging in to CaseCenter through the Web Interface 13 3 CaseCenter Main Application SCreen ccsscsccccscsscsccccsccccsccccsceccccnccscescccsceccecececececscscscececess 16 SIUE PAINE e ee E E arretra 16 3 1 1 Managing a CaseCenter User ACCOUNT sarssssirsiarissnssssnnnseionrsannrii niniin r i EETA NA TAE ATE NE TEES EEEE 18 3 1 2 Changing a UserPassWofd iii 18 OZ N ONU OPH ONS eera E T E E ATE T E 19 4 SUACS and FO CT Sissies acy a ara A E EEA 20 di Folder Tree Pane leirien Ennn EAE EAE EEE 20 4 1 1 Polderto0FMildiifScaic rotta 21 4 1 2 Folder operation BUON 21 4 2 Slide Attributes and Process OptionS ii 25 GZ k Sde DUES oen EE
2. Default Simple Show description or Slide tray from the View type drop down list Default view is Slide tray The folder content panel changes according to the selected view type but if a Case contains several Blocks the root content of the Case and of the Blocks are displayed as well July 10 2015 Rev 1 3DHISTECH Ltd 24 54 CaseCenter 2 6 User s Guide 4 Slides and Folders SDHISTECH 2 6 RTM Mr Doe Joh s CaseCenter 2 6 1 51798 998 999 CaseCenter B eg paren ee Change profile e Slides amp Folders ESI Quick search folder SEID FTA Quick search Slide View type Open Slides in aJe je B IO La a Show description Y Pannoramic Viewer fey Fi ix Preview wi atroce Image Type Slide name Barcode Organ Staining Scan Date Status Slide size SU name Edit Hospital A Gq INew Cases Unassigned 7 IO Case 198 08 o Ei Case 198 08 lt 3 gt Macro description Lorem ipsum dolor sit amet consectetur adipiscing elit Cras purus eros hendrerit a tincidunt vel ullamcorper nec neque Donec egestas auctor nulla tincidunt porta felis E Case 995 12 lt 1 gt scelerisque id Nam tellus enim placerat ut accumsan id sodales sed leo Pellentesque vestibulum pretium leo vitae adipiscing Aliquam nec nibh vitae tellus sollicitudin iaculis Mauris elementum C Unidentified cases and slides tristique porta Fusce sodales aliquam lectus nec
3. Department 1 De ent 2 Read amp Write SERE Read only sia E Cancel Accept July 10 2015 Rev 1 3DHISTECH Ltd 23 54 CaseCenter 2 6 User s Guide 4 Slides and Folders Delete folder After clicking the Delete button a dialog window opens Click Delete to confirm the removal of the folder Are you sure you want to delete this folder Hospital A iNew Cases Unassigned Casem 995 12 E Cancel Q Delete NOTE Only empty folders can be deleted therefore upon clicking the Delete button a notification message appears that the folder cannot be deleted as it contains sub element s The folder that will be deleted is highlighted on the left in the folder tree e 2 New Case Creates a case under the actual folder Note that a case cannot be created under an other case or block Similarly to the Create new folder window description can be added to the case as well as determining users and groups and their access rights to the case Click the Accept button to create the case e New Block Creates a block under the actual case Note that you cannot create a block under an other block Description can be added to the block as well as determining users and groups and their access rights to the block Click Accept to finalize block creation 4 2 Slide Attributes and Process Options 4 2 1 Slide attributes The view of slide attributes can be modified by selecting one of the four view modes
4. Ltd 51 54 CaseCenter 2 6 User s Guide 9 Troubleshooting 9 4 CaseCenter Server upgraded by the Administrator In case the CaseCenter server is reinstalled by the administrator the browser cache must be cleared on the client s side Follow the below procedure to clear browsing data in Google Chrome 1 Press Ctrl Shift Del OR e Click the Chrome menu _ on the browser toolbar then Tools e Select Clear browsing data 2 From the drop down menu at the top of the dialog window select the time how far back in time you want to go It is advised to select the beginning of time as time range Make sure that the following boxes are checked e Delete cookies and other site and plug in data e Empty the cache Clear browsing data Obliterate the following items from the beginning of time Clear browsing history Clear download history fl Delete cookies and other site and plug in data fl Empty the cache Clear saved passwords Clear saved Autofill form data Clear data from hosted apps Deauthorize content licenses Learn more Clear browsing data Cancel 3 When you finished checking boxes click Clear browsing data July 10 2015 Rev 1 3DHISTECH Ltd 52 54 CaseCenter 2 6 User s Guide 9 Troubleshooting 9 5 Slide name is too long The maximum length of slide name is a string of 70 characters in CaseCenter but if scanning options are set in the Scanner software application that the digital slide
5. NOTE Staining and Expiration date cannot be modified for Virtual Slides Edit Virtual Tray Slide name Block 995 712 Uploader user John Doe Slide Description Status Mew VT Content i Slide Preview anna a 995 12_CD20 t 995 e 12 _ CD10 Slide size 15 93 kB SU name su_local Di Cancel Automatic Slide deletion time T W Never expire Slide path Hospital AINew Cases Unassigned Case 995 12 Block 995 12 _ Hospital AiINew Cases Unassigned Case 995 12 Blocia 995 12_1 Accept e View type select any of the following options O Default Slide tray view o Simple o Show description o Slide tray e Order by you can select any of the following ordering methods from the drop down list o Image type o Slide name o Organ o Staining July 10 2015 Rev 1 3DHISTECH Ltd 34 54 CaseCenter 2 6 User s Guide 4 Slides and Folders o Scan date o Status o Custom Order NOTE Since slides can be reordered by dragging in Slide tray view mode order will automatically be displayed as Custom order Checkbox Check to select every item of the Folder Case Block for further operations Align Click to align selected slides based on a reference degree by which slides in a set can be rotated to an identical orientation Slides before alignment Slides after alignment ral ra amp 995 12_CD20 995 12_Ki 67_1 995 12_CD20 095 12 _Ki 67_1 995 12_C
6. New e Public Share MI For users that are not registered on a CaseCenter server slides can be accessed via opening a URL in platform independent InstantViewer or Pannoramic Viewer 1 15 4 if installed Follow the below steps to share a slide publicly 1 2 July 10 2015 Rev 1 Select the slide or slides to be shared Click hie Select an already existing user created as Public Share User by the Administrator from the Select User drop down list or create a new user in the or Create User field of the Public Share Slide window The Share URL is generated after the existing user is selected or the new user is created by clicking amp ceste Select sharing rights then copy the URL and send it to the user After clicking Accept the share is visible on the Shared by me panel of the Share window 3DHISTECH Ltd 29 54 CaseCenter 2 6 User s Guide 4 Slides and Folders Public Share Slide Select User Or Create User Public Share User 01 Public Public Sr a Create Select Sharing Rights Share URL Read amp Write http lug2 3dh local CaseCenterindex php UseriD 28df076c0fbe3c O Read only Cancel accept 5 If you would like to cancel the public share remove user from the user list e Upload macro _ i Click this button to upload macro images Only JPEG or JPG images can be uploaded file size is maximum 1MB Uploading a macro Upload file C Users Publ
7. auctor Maecenas vulputate fringilla sapien in suscipit In hac habitasse platea dictumst Maecenas a odio ante ac porta eros Etiam imperdiet Q Education lt 1 gt vulnutata arne anast mallis macca enmmorin id D Frozen Section e Macro Image Block II nla nla n a 20120801 F New v amp 363 23 kB su_local Wi HIS 03 58 30 Es C Lost and Found Slides l C Research Routine Pathology wi 2 Macro Image Block III n a n a n a nia New v 377 19kB su_local f The order of attributes belonging to a specific view type may vary according to the settings made by administrators The selected View type will be saved automatically and loaded next time you log in Attribut es according to Show description view type Checkbox Preview Thumbnail view of the slide or image Slide type 2D Slide 3D Slide MacroSlide TMA Project or TumorBoard Project Slide name Barcode Description Organ name of the organ where the tissue specimen was originally sectioned from Staining name of the applied stain Scan date time of slide digitization Status indicates the stage the slide is in Status attribute can be selected from the drop down menu and by default it is set to New either newly imported scanned or uploaded Once a slide is opened its status will be automatically switched to Examined Statuses Diagnosed and Reopened both can be set manually Slide size SU name July 10 2015 Rev 1 3DHISTECH Ltd 25 54
8. button to cancel sharing them with a user normal moderator public share or users of a group July 10 2015 Rev 1 3DHISTECH Ltd 48 54 CaseCenter 2 6 User s Guide 7 Search in CaseCenter Server Select Search from the menu options to search for slides and 7 Search in CaseCenter Server folders stored on the CaseCenter server 6 RTM Mr Doe John ere iii CaseCenter 2 6 1 51798 998 999 CaseCenter 00 25 minutes left Change profile 6 8 Search v t Text Organ Status Save as i All organ v All status v Save A Search Date From Date To Staining Service Unit Saved searches All staining v All Service Units v Not set v Delete Reset y ne View type Open Slides in Slides gt BI La 19 Lai x a Simple v InstantViewer v Folders In this window you can search for the following attributes blocks and slides e Date from to e Organ selectable from list e Staining selectable from list e Status selectable from list Service Unit selectable from list Text search for character string in slide name and in the description fields of folders cases Except for temporary LDAP users search parameters can be saved for later use by entering a text into the Save as field and clicking Save or delete after selecting the entry from the Saved searches drop down list then clicking the Delete button Search results will be displayed after clicking
9. click m in the Pannoramic Viewer toolbar NOTE It is available for you to open a slide that is included in a Teleconsultation session and attend teleconsultation via CaseViewer For more information read CaseCenter server paragraph at the end of section 2 in CaseViewer 1 4 User Guide July 10 2015 Rev 1 3DHISTECH Ltd 47 54 CaseCenter 2 6 User s Guide 6 Slide Sharing 6 Slide Sharing Select the Share menu option from the main menu If a user has shared a slide with you it will be listed in the Shared with me window pe 2 6 RTM Mr Doe John a n x CaseCenter 2 6 1 51798 998 999 CaseCenter 00 29 minutes left Change profile w Share v SI gt Quick search _ View type Open Slides in shared wihme SI Lon Default v InstantViewer v Shared by me J Preview preve Image Type Slide name amp Barcode Privilege Share owner Organ Staining Scan Date Slide size SU name Edit 2008 04 23 17 08 24 BE 2D Slide 198 08_GI 198 08_G_ ReadMrite amp Mr Smith Bill colon ToluidinBiue 2908 0423 4534MB su_local Zi pei BC 2DSlide 198 08 _G 198 08_G_ Read Write 4 Mr Smith Bill colon Toluidin Blue 111 65 MB su_local Al You can share your slides with other users and or groups in the Slides amp Folders window see section 4 2 2 Slide actions e When you share a slide on the server all the designated users will be able to see the slide if they check their Shared with me window You can use the C
10. mode Quick search Slide View type Order by Open Slides in D lis 19 La toa Ls A a Default v Slidename v InstantViewer v E Case 995 12 Hin Macro description Lorem ipsum dolor sit amet consectetur adipiscing elit Cras purus eros hendrerit a tincidunt vel ullamcorper nec neque Donec egestas auctor nulla tincidunt porta felis scelerisque id Nam tellus enim placerat ut accumsan id sodales sed leo Pellentesque vestibulum pretium leo vitae adipiscing Aliquam nec nibh vitae tellus sollicitudin iaculis Mauris elementum tristique porta Fusce sodales aliquam lectus nec auctor Maecenas vulputate fringilla sapien in suscipit In har hahitaccea nlataa dirtumet Maaranac andin anta ar norta arne Etiam imnardiat wulnutata arne anat moallic maces rommoadno id Examined Macro 995 12 lymphatic organs n a 2012 08 01 05 54 23 82 2 kB su_local CaseView mode is available through HIS Hospital Information System A link is generated for a specific case in HIS and upon opening this link with a user account in CaseView mode a restricted user interface of the slidemanager view is displayed Available functions e Editing or handling slide data e Attachments e Open slide e Change view type e Share e Public Share Slide e Upload macro e Capture macro Inactive functions e Folder tree e Copy slide e Move slide e Delete slide July 10 2015 Rev 1 3D
11. receives its barcode string as its file name the name string can be as long as 256 characters In CaseCenter during editing any of the attributes organ staining etc of a slide which name contains more than 70 characters make sure to cut or rename the slide and type less than 70 characters in the file name field July 10 2015 Rev 1 3DHISTECH Ltd 53 54 CaseCenter 2 6 User s Guide Index Index B BR e 10 11 20 21 23 24 25 27 28 34 C CASS N EE i 10 20 21 23 24 25 27 28 34 51 CISECENEEr sciistica 7 8 9 10 11 12 13 14 16 18 20 40 44 45 47 48 50 51 52 CSO OW aa rates ar 39 E Ellie 17 18 23 26 27 32 38 47 F PON CS COA ai etneo 8 G RS OUD APEE E EE E 7 9 10 11 19 22 23 24 25 28 40 42 45 47 49 H 1 39 Ubi 10 L EDAP orane nasa ein tini adizi nozioni iii ae 17 48 49 p Pannoramic VIEW 8 9 11 12 13 34 36 38 40 44 45 46 50 S OSs 6 Pee O A EE ene SA RI 4 8 9 10 19 20 27 48 49 SCR nie 8 9 10 11 12 13 14 16 18 19 20 28 40 44 45 47 48 50 51 SCRUTA 10 40 CRE RR 9 10 11 19 28 39 45 47 T TRISCONMSU AU ON isdiececces ice caseninnccceneacceceaetdddastinasdateecete 7 8 9 10 11 12 13 19 40 41 43 44 45 46 U We e e N E atsaccot ateteuet in 9 10 11 12 18 29 34 35 39 40 45 July 10 2015 Rev 1 3DHISTECH Ltd 54 54
12. time Other participants may request permission to modify the slide from the Host July 10 2015 Rev 1 3DHISTECH Ltd 41 54 CaseCenter 2 6 User s Guide 5 Teleconsultation 5 3 Creating a Teleconsultation Session 1 Switch to Teleconsultation window then select the TC Requests option 2 6 RTM Mr Doe John 1 nd CaseCenter 2 6 1 51798 998 999 CaseCenter 00 28 minutes left Change profile Teleconsultation v gt TC invitations es rs TC requests i Title amp Startdate Expiration date Edit TC O Teleconsultation_01 2015 04 3009 00 2015 05 04 09 00 Al 2 Click to create a Teleconsultation session e Fill in the fields in the General Information panel You can name the session assign a start date Now is active as default and Expiration date as well as write a description about the session itself Create new Teleconsultation General Information Teleconsultation title Teleconsultation_01 eae ce ee ees Start date hour min Expiration date Users and Groups G Now 2015 04 30 a T 00 T 4 days later T Description Cance Accent July 10 2015 Rev 1 3DHISTECH Ltd 42 54 CaseCenter 2 6 User s Guide 5 Teleconsultation e Inthe Slides window click the desired folder in the folder tree then click Add next to the slide preview at the right side of the Select Slides panel To add all the slides included in the selected folder click 4642 Slides can be removed from the
13. 15 Rev 1 3DHISTECH Ltd 9 54 CaseCenter 2 6 User s Guide 1 About CaseCenter 1 1 Storing and Managing Digital Slides through CaseCenter CaseCenter is a platform for managing folders slides cases blocks and other documentations The figure below demonstrates how slides can be stored and managed on a server H n 4 s A Service Unit is an element of the system where slides are physically stored on and slide processes take place at as well slide access and management is attained through the HUB Users who have registered on the server registration is performed by the server administrator or a moderator user can manage and use their slides on the server in the following ways e upload slides to the server e arrange slides in folders cases or blocks for example group slides according to their staining types or your research projects e share slides with other users o with users who have an account on the same CaseCenter either having read only or read write access to the folder case block containing your slide or if you share the slide with them explicitly o Public Share Users whom with slides can be shared via opening the URL of the share in a browser o with users who will access the slide via E School invite other users into Teleconsultation sessions to discuss slides e participate in Teleconsultation sessions initiated by another user July 10 2015 Rev 1 3DHISTECH Ltd 10 54 Case
14. CH Ltd All Rights Reserved Intellectual property related to the 3DHISTECH products are as follows EP 1 789 831 US 7 663 078 EP 2 024 772 JP 2009 512685 US 12 301 781 EP 1 644 767 JP 2007 516451 US7 327 515 EP 1 994 398 JP 2008 557835 US 12 281 566 U0700210 US 6 246 785 HU0900142 HU0700404 PCT HU2007 000065 EP 08762668 5 US 12 663 537 PCT AT2006 000492 JP 2008 542552 EP 06817469 US 12 095 545 PCT AT2006 000493 EP 06817470 5 US 12 095 596 HU0900741 US 61 264 732 US 11 826 752 P0401870 PCT IB2005 050344 US 11 662 976 HU0700409 US 12 042 050 US 77 636 144 and 007502032 The above mentioned granted patents granted utility model registered trademarks pending international and national patent applications and the other corresponding IP are the sole properties of the 3DHISTECH Ltd 3DHISTECH Ltd is not liable for damage of whatever nature including but not limited to general or specific damage indirect damage consequential damage or incidental damage including the results of the analysis of the digitized slides for example change of health status related to erroneous diagnosis from the digitized slide s that stems from or is associated with use of Product digitized slides quality of staining quality of stained slides quality of used method of staining 3DHISTECH Ltd assumes no responsibility for the functionality and fault free condition of your application programs Workflows VBA macros Commande
15. CaseCenter 2 6 User s Guide 4 Slides and Folders e Edit the icon is displayed only if you have write access to the specific slide Slide name 995 12 CD20 Uploader user John Doe Slide Description Organ Staining lymphatic organs T IHC_CD 0 T Status Automatic Slide deletion time Examined T W Never expire Slide in content Preview Slide name Slide path Block 995 Hospital AlNew Cases Unassigned Case 995 12_ 12 Block 995 72 _ Barcode 995 12 CD20 Slide size 829 91 MB SU name su_local Cancel Accept In the Edit Slide window the following slide attributes are displayed by default e Slide name NOTE Slide name cannot be longer than 70 characters and make sure it does not include the amp character For more information see sections 9 5 and 9 6 e Uploader user The name of the user that has uploaded the particular slide e Description o Click the Description field to enter modify information regarding the specific Folder Case or Block e Staining o Types can be set by Administrator select one from the drop down menu e Organ o Types can be set by Administrator select one from the drop down menu e Status o New July 10 2015 Rev 1 3DHISTECH Ltd 26 54 CaseCenter 2 6 User s Guide 4 Slides and Folders o Examined o Diagnosed o Reopened e Barcode e Slide size SU name e Automatic Slide deletion time e Select Never expire or specify a date NOTE Uploader use
16. CaseCenter 2 6 User s Guide 9 Troubleshooting 9 Troubleshooting 9 1 I Cannot Connect to the CaseCenter from Pannoramic Viewer Check the following to ensure that you can access the server 1 Is your Internet connection in order 2 Are you entering the correct name or address to the server If you are not sure that you are entering the correct data in the connection dialog contact your CaseCenter administrator who can give you the name and or address of the server 3 Are you entering the correct user name and password You can double check by logging in to CaseCenter via the web interface If you can log in to the Server that way your user name and password is correct 9 2 Cannot Open the Slide from the Link Someone Sent Me Check the following to ensure that you can access the server and the slide stored there 1 Is your Internet connection in order 2 Does the link point to a CaseCenter where you are a user e Check the server name in the link 3 Is the CaseCenter working e Double check by logging in to CaseCenter from Pannoramic Viewer see section 2 1 via the web interface see section 2 2 9 3 Cannot Change My CaseCenter Password You might not be able to change the password assigned to you by the administrator who enables or disables password resetting when your account is created If you have trouble with resetting your password contact your CaseCenter administrator July 10 2015 Rev 1 3DHISTECH
17. Center 2 6 User s Guide 1 About CaseCenter 1 2 1 3 Accessing a Slide Whether you can open and view a slide stored on a CaseCenter server depends on the following criteria e you can always access the slides for which you have read only and upload slides with read write access rights e you can see slides that other users share with you for instructions see section 6 Administrators or users with moderator privilege can give permission to particular users or groups for accessing specific folders block cases This means that you might not be able to see all the slides stored on the server and it is possible that some of the slides are not even visible to other users except they are shared For example if a parent folder is protected some of its content is hidden because you are a user with limited user privileges therefore the folder name is grayed out but it is possible for you to access the content of a sub folder if you are permitted by the administrator or a user with moderator rights Uploading a Slide to a CaseCenter You need Pannoramic Viewer to upload files to the server O Tp Since the upload may take a significant amount of time depending on the slide size it is recommended that you upload the slide to the server before starting a Teleconsultation session You can only upload one slide at a time from Pannoramic Viewer Administrators can perform bulk uploads via file transfer 1 Launch Panno
18. D20 995 12_K 67_1 995 12_CD20 995 12 _Ki 67_7 lymphatic organs lymphatic organs lymphatic organs lymphatic organs IHG_CD20 IHC_KI 57 l IHC CD20 IHC_KH6T 2008 05 23 08 50 12 2013 10 18 09 48 39 2008 05 23 08 50 12 2013 10 18 09 48 39 829 91 MB T3 B 829 91 MB Tai B su_local su_local su_ local su_local Folder Case Block name Attachment Click to upload files as attachments and to display the list of attachments if there is any belonging to the actual folder NOTE Attachments can be uploaded for the current folder and not for a specific slide Omit using accented letters in file names you want to upload as these characters will change after batch download of attachments and decompressing the ZIP file Important an If an attached file name starts with a character or the file extension contains a space its downloading may fail depending on the browser type July 10 2015 Rev 1 3DHISTECH Ltd 35 54 CaseCenter 2 6 User s Guide 4 Slides and Folders To attach a file to the actual folder follow the below steps 1 Click Choose File in the Attachments window to upload a file as an attachment 2 Select the file then click Open in the File Upload window 3 Click the Upload button in the Attachments window to upload the file ral File name Upload date Download Dette Upload file Choose File No file chosen Upload e Use the selection checkboxes at the first column or
19. E E AAAA AEN 25 B22 SNS CU ONS APA E EE N E TR 27 4 CASS VIEW MOOC coristi reinsa Er atri EET E OEEO 39 5 Telecons UNA Gl ON sarni nE EEE EE E E E N 40 5S1 Overview of TeleconsuhtatiON eessen o ire 40 5 2 Requirements and Privileges for Hosts in a Teleconsultation SESSION 40 5 3 Creating a Teleconsultation SCSSION ccccccssecccssccccseccceneceeaeececeeseeeseecessucesseeesseaecesegecetees 41 5 4 JOINING a Teleconsultation SESSION ccccccesecccessceceesccecesececeeececsuscecseneceseaesesseeceseueeeseeeeeeeees 43 5 5 Opening a slide via Teleconsultation i 44 5 6 Working Simultaneously on a Slide in an Online Teleconsultation Session 45 ESE visser cscs E E ET EE E A E T ANA 47 7 SCcarch in CaseCenier SEVE Lai 48 July 10 2015 Rev 1 3DHISTECH Ltd 2 54 CaseCenter 2 6 User s Guide S Users Oe GIOUDS irreali darai enrica carter 49 OTR GU IES MOO ME aim 50 9 1 Cannot Connect to the CaseCenter from Pannoramic Viewer 50 9 2 Cannot Open the Slide from the Link Someone Sent Me cccccesesceseseceeseeeneeeeneceeeeeeeees 50 9 3 Cannot Change My CaseCenter Password 50 9 4 CaseCenter Server upgraded by the Administrator rei 51 I ah gts Lag a io 004 9 RR EE 52 5 RR E 53 July 10 2015 Rev 1 3DHISTECH Ltd 3 54 CaseCenter 2 6 User s Guide Disclaimer Copyright 2001 2015 3DHISTE
20. F THE POSSIBILITY OF DAMAGE AND ON ANY THEORY OF LIABILITY ARISING OUT OF OR IN CONNECTION WITH THE USE OR PERFORMANCE OF THIS SOFTWARE Further Information For the latest information on 3DHISTECH products and services please visit our website at http www 3dhistech com Company Address 29 33 Konkoly Thege Miklos Street Building 6 1121 Budapest HUNGARY July 10 2015 Rev 1 3DHISTECH Ltd 5 54 CaseCenter 2 6 User s Guide Character Types and Symbols Example Abbreviation or term that is explained in section Terms and Abbreviations Example Words or characters that appear on the screen These include field names screen titles push buttons and menu names paths or options Keys on the keyboard For example function keys such as F11 or the Ctrl O key combination Example Cross references to other documents Warning Indicates that you need an additional module to use the feature or that there are prerequisites for the task Important gt gt Contains an important piece of information or a recommendation The application will work if you choose not to follow the recommendation but its performance might be less than optimal Tip Contains a suggestion about using the application in some other way or to some interesting purpose July 10 2015 Rev 1 3DHISTECH Ltd 6 54 CaseCenter 2 6 User s Guide Terms and Abbreviations Annotation A p
21. HISTECH Ltd 40 54 CaseCenter 2 6 User s Guide 5 Teleconsultation 5 Teleconsultation Teleconsultation gives you access to digitized slides from a remote location Slides can be examined and evaluated by users who have invited by the host during a Teleconsultation session You can consult about slides with other users in real time or in asynchronous mode also with the chat support AN Important Note that the file sizes of digitized slides are large the size of the MRXS file and the associated folder is often 1GB or above Therefore it is recommended that you use an Internet connection that has at least 1000 kilobit s capacity when you are uploading slides or when you participate in a Teleconsultation 5 1 Overview of Teleconsultation You can use Teleconsultation for telepathology to evaluate digitized slides stored on a 3DHISTECH CaseCenter server via the Internet using the CaseCenter application in online mode You will need the Teleconsultation module of the Pannoramic Viewer to upload slides one by one to a 3DHISTECH CaseCenter server Uploading the slide creates a copy on the Service Unit keeping the original slide on your local computer 5 2 Requirements and Privileges for Hosts in a Teleconsultation Session e Ifthe Host quits the group the Teleconsultation session closes for all participants Other participants can leave the session without terminating it e The Host can modify the slide by adding annotations at any
22. Queue time has expired Please log in again July 10 2015 Rev 1 3DHISTECH Ltd 15 54 CaseCenter 2 6 User s Guide 3 CaseCenter Main Application Screen 3 CaseCenter Main Application Screen The main application screen can be divided into the following elements e Header Bar 1 that includes the CaseCenter logo version information the name of the CaseCenter server you are connected to and the User panel e Main Menu Selector 2 is a drop down element from which you can select the desired menu option A i button is located at the right side of this bar Click this button to immediately update the content of the display after you effect a change for example in the folder structure but normally the screen is automatically updated within four seconds e Menu Panel 3 modifies according to the selected menu option Panels may be displayed differently according to uniquely customized column settings for the specific user type EA CaseCenter SE 3DHISTECH Ltd Doe John 2 5 1 41905 997 999 00 29 minutes left Show profile Ce Slides amp Folders X Quick search folder gt TER ce a Quick search Slide 3 a emm ma View type Order by ia Open Slides in n le Slide tray Slidename v 4 Pannoramic Viewer v 191 is io es Ss O E Block 995 121 F 0 amp Hospital A z Micro description of Block Lorem ipsum dolor sit amet consectetur adipiscing elit Cras purus eros hend
23. Selected slides list one by one by clicking ren Create new Teleconsultation or to remove all of them click Remove alsides General Information Eq Hospital A Eq INew Cases Unassigned E Block 198 08_I Block 198 08_Il Block 198 08_Il Block 198 08_D Case 995 12 lt 2 gt Block 995 12_I lUnidentified cases and Education lt 1 gt Gy Frozen Section I INew_Cases gt Slides Users and Groups Selected slides a Side added Side added Oas Ox Remove 198 08_G Remove 198 08_G Q Cancel Select slides Slides can be accessed in a folder with read write permission only 198 08_G_l 2D Slide 198 08_G_ 2D Slide 198 08_G_I 2D Slide 198 08_G_1 2D Slide 198 08_G_Ill 2D Slide Ww x Add all Remove all slides 2D Slide 2D Slide O accent e Finally select the participants in the Users and Groups window and click O acent Create new Teleconsultation Add User A Prof Brad Bronson amp DDep1 amp DDep2 amp F Frozen amp R Research amp R Routine amp S Student General Information Slides Users and Groups Add Group amp Department 2 Moderator amp Normal amp Restricted Cancel July 10 2015 Rev 1 3DHISTECH Ltd amp Prof Anton Aronson amp Prof Charlie Chang amp Department 1 Accept 43 54 CaseCenter 2 6 U
24. ally creates a copy of the selected slide s in the destination folder e Move la Moves the selected slides to the desired folder in the folder tree A window similar to the Duplicate slide window appears select the destination folder to which the selected slide s will be moved from the original folder e Delete LO Removes the selected slides and the related data from the server Delete slide A The following slides are part of one or more TCs VSS or VTS Note that slide deletion is irreversibile Preview Slide name Contain object A 995 12 CD10 in VSIVT a 995 12 CD20 In VSIVT 995 12 _KFG _1 in VSIVT Si Cancel Delete slide July 10 2015 Rev 1 3DHISTECH Ltd 28 54 CaseCenter 2 6 User s Guide 4 Slides and Folders e Share H Click this button to share the selected slide s or project s with existing CaseCenter users or groups Sharing a slide generates a link pointing to the original slide share Slide Add User s Prof Anton Aronson A Prof Brad Bronson d Prof Charlie Chang A DDepi A DDep2 fm F Frozen i R Research R Routine Read amp Write 4 3 Student Read only Add Group s Normal Moderator Department 1 amp Restricted amp Department 2 Read amp Write Read only m Accept When a slide is shared with a user or groups it will show up in their Share menu and its status will be automatically set to
25. ant Open CaseCenter interface in one tab only with your browser because connection issues may arise when working on the same server in several tabs If there are no free slots left to access the server you receive a message displayed in the login window informing you that you are placed in the login queue CaseCenter 2s Login sDHISTECH Server is full You are in the login queue Please wait Login queue position 1of1 Cancel You get in the Login queue based on your user level which means that the higher the level is the sooner you are allowed to log in the higher ranked user is put forward but behind the users of the same level July 10 2015 Rev 1 3DHISTECH Ltd 14 54 CaseCenter 2 6 User s Guide 2 Connecting to CaseCenter Queue number position in the queue is displayed and automatically updated You may leave the queue by clicking Cancel and every other user behind will be placed forward CaseCenter 25 Login sDHISTECH You can log in now 01 57 minutes lett Password C Remember my login on this computer Cancel Login If you are at the first position in the queue and a license is set free then you will be notified that you can access the system If you do not wish to log in you will be removed from the queue after a specified amount of time has passed since the notification is displayed and the possibility of logging in is given to the user next on hold CaseCenter 26 Login sDHISTECH
26. ant to add to the structure This option is available for users with Read Write access rights therefore the button is inactive if a folder cannot be created at that level Access permissions for the new folder can be added only when with Read Write access rights and in Moderator user level 1 July 10 2015 Rev 1 In the folder tree click the desired folder in which you would like to create the sub folder and if active click The Create new folder window opens Type in the Folder name add some information in the Description field if necessary Select users and or groups you would like to give access to this folder and set their permissions Click the right arrow buttons to add them to the selection list Click the left arrow button to remove items from the lists By default users are displayed with the given permissions for the parent folder and will be marked with red if you modify their permissions 3DHISTECH Ltd 22 54 CaseCenter 2 6 User s Guide 4 Slides and Folders e a Edit folder By default you can modify the folder description only Patient or case related information can be entered into the description field Upon clicking on the Description field in case it includes any text of the selected folder case block in the Slides amp Folders panel a window similar to the following appears BE Case description Case 198 08 Description Macro description Lorem ipsum dolor sit amet cons
27. articular detail of a digitized slide Host User who uploaded the digital slide to CaseCenter and who initiates the Teleconsultation about the slide CaseCenter user group Group created by a CaseCenter administrator Participant User invited to participate in the evaluation of a slide stored on CaseCenter Teleconsultation Provides access to digitized slides for several users and supports their collaboration in inspecting and evaluating the virtual slide Teleconsultation group Group created by the Host for a Teleconsultation session independently of the user groups that exist on CaseCenter Several Teleconsultation sessions and therefore several Teleconsultation groups can be activated on a CaseCenter in parallel Telepathology Teleconsultation in the field of pathology pathologists exchange information and evaluate a slide together via Teleconsultation July 10 2015 Rev 1 3DHISTECH Ltd 7 54 CaseCenter 2 6 User s Guide 1 About CaseCenter 1 About CaseCenter CaseCenter is an application through which you can store and manage virtual slides on a designated server CaseCenter is a part of the 3DHISTECH Product Family that supports tasks in the routine and research workflow of pathologists Brightfield Scan ToServer Fluorescent CaseCenter TMA Local File System PathoNet I E School 1 Digitize slides which can also be tissue microar
28. aseCenter groups created by the administrator for example a group of users who specialize in a particular cancer type 2 6 RTM Mr Doe John ae CaseCenter 2 6 1 51798 998 999 CaseCenter 00 29 minutes left Change profile w Share v s shade Quick search A View type f apen Slides in im Simple InstantViewer a prod by me fs iprevi Label Area T i Pe Privi O cala i r i ha review Image Image Type Slide name Barcode rivilege Share to rgan Staining Scan Date Slide size SU name Edit URL link 8 05 gt ee 2D Slide 995 12_CD10 995 12_CD10 Read Write amp Mr Smith Bill lymphatic organs IHC_CD10 2005 0223 68687MB su_loca A 2008 05 A oe 2D Slide 995 12_CD10 995 12 CD10 Read Write a Dr Anderson James lymphatic organs IHC_CD10 pr 686 87 MB su_loca a gt 2008 05 2D Slide 995 12_CD10 995 12_CD10 Read Write Department 1 lymphatic organs IHC_CD10 cane 686 87 MB su_loca 4 A 2DSlide 995 12_CD20 995 12_CD20 Read Write Mr Smith Bill lymphatic organs IHC_CD20 peo 829 91 MB su_loca Al A ole 2D Virtual Slide 995 12_Ki 67_1 995 12_Ki 67_1 Read Write West Abraham lymphatic organs IHC_KI 67 cere 737 B su_loca 7 A e Click to edit slide data e To view the URL for the shared slide click fi Public share URL link httpug 2 3dh local CaseCenter index php module share e Tick the checkbox on the left of the thumbnail image of the slide then click the
29. can perform an immunohistochemical analysis on a Slide set If you purchase the TMA module as well you can run your TumorBoard analysis on a tissue microarray and score the TMA project in TumorBoard e With HistoQuant MembraneQuant NuclearQuant FISHQuant CISHQuant CISH RNSQuant and DensitoQuant modules you can define algorithms to measure various parameters on a slide Combined with TumorBoard you can run the Quant algorithm on one slide or on a set of slides grouped into an TumorBoard project For more information on Pannoramic Viewer modules see Pannoramic Viewer 1 15 4 User s Guide 4 You can upload slides to a CaseCenter server also from the local storage with file transfer via Teleconsultation in Pannoramic Viewer Teleconsultation via Pannoramic Viewer allows you to view remote slides slides stored on a CaseCenter server With this feature of Pannoramic Viewer you can also host a Teleconsultation session or participate in a session initiated by another user 5 You can also share slides for E School For information on that product see E School 1 11 User s Guide One example of a server based teleconsultation solution is www pathonet org Slides stored in CaseCenter server may be shared and can be opened with CaseViewer application CaseViewer can be downloaded by clicking W at the top left corner of the CaseCenter login site For more information the application and usage see CaseViewer Help Guide July 10 20
30. d 16 54 CaseCenter 2 6 User s Guide 3 CaseCenter Main Application Screen For users who cannot modify their profile data for example LDAP users View profile is displayed instead of Change profile Upon clicking View profile the User data window is displayed User tithe Family name Mr Smith Given name Bill E mail billsmith domain com Other Contact 55 555 555 Specialties If you click on the Change profile button the Edit user window opens in which the following options are available for you to change user preferences e Youcan change your title family and given name e mail address password other contacts and specialties User name and Moderator right is given by the administrator therefore the User name field is inactive in this window NOTE Use only printable ASCII characters 32 126 when creating a new password d Edit user User title Family name User name Doe John Doe Given name Old Password John PT Tritt t E mail Password john doe mexample com Other Contact Specialties Cancel Accent July 10 2015 Rev 1 3DHISTECH Ltd 17 54 CaseCenter 2 6 User s Guide 3 CaseCenter Main Application Screen NOTE Moderator user is allowed to set other users access rights for folders to which he she has RW right except to folders with R or 0 rights Click KA to log out from the CaseCenter interface NOTE If closing the browser tab window and your browser is set not
31. ect one slide only then you click this button and the box in which the following message appears you can select the type of virtual item to be created July 10 2015 Rev 1 3DHISTECH Ltd 32 54 CaseCenter 2 6 User s Guide 4 Slides and Folders In the folder content panel virtual slide is marked with a di label and virtual tray is with a label next to the preview image of the virtual item Reopened Y New v 905 12 Ki b7_1 Block 995 12 995 12 Ki 67_1 n a lymphatic organs nia IHC_KI 57 n a 2013 10 18 09 48 39 2013 10 17 10 50 41 T37 B 15 93 KB su_local su_local If you edit the data of the virtual slide or tray the following windows are displayed Edit Virtual Slide Slide name 995 12 Ki 67_1 Uploader user John Doe Slide Description Organ Staining lymphatic organs IHC_K 6 Status Automatic Slide deletion time Reapened T Never expire VS Content Preview Slide name Slide path 995 12 Ki Hospital AlNew Cases Unassigned Case 995 P 67 1 12 Block 995 12 _ Barcode 995 12_Ki 67_1 Slide size 7378 SU name su_local x Cantel Accept July 10 2015 Rev 1 3DHISTECH Ltd 33 54 CaseCenter 2 6 User s Guide 4 Slides and Folders At the bottom areas of these windows sections such as VS Content and VT Content display the preview image and related data of the included slide or slides
32. ectetur adipiscing elit Cras purus eros hendrerit a tincidunt vel ullamcorper nec neque Donec egestas auctor nulla tincidunt porta felis scelerisque id Nam tellus enim placerat ut accumsan id sodales sed leo Pellentesque vestibulum pretium leo vitae adipiscing Aliquam nec nibh vitae tellus sollicitudin iaculis Mauris elementum tristique porta Fusce sodales aliguam lectus nec auctor Maecenas vulputate fringilla sapien in suscipit In hac habitasse platea dictumst Maecenas a odio ante ac porta eros Etiam imperdiet vulputate eros eget mollis massa commodo id cancel Accent Description field becomes locked whenever a user has initiated editing so you will not be able to modify the content Moderator users are allowed to change user permissions If you would like to have the access right of a user or user group to be changed you can contact a Moderator user A moderator is always marked with a green avatar Click Accept to confirm changes Edit Case Case name Case 995 12 x Description Macro description A Lorem ipsum dolor sit amet consectetur adipiscing elit Cras purus eros hendrerit a W tincidunt vel _ ulamconmer ner neaue Doner enestas auctor nulla tincidunt porta felis Add User s Subfolders inherit the permissions of the parent folder A Dr Anderson James emo den A ALA Dep 2 joe Johi Je Frozen F i Read amp Write _ 32 2 eg Read only i Add Group s Administration department Dem
33. ic Pictures Slide name 10307 07_ER_ Organ X um per pixel not set 250 Automatic Slide deletion time Y um per pixel Never expire 250 x Close Upload e Capture macro If a webcam is connected to your computer or it is installed with a built in camera it can be used for capturing macro images directly 1 Click ry 2 Chrome pops up a message to allow using the camera Click Allow to accept httpy fug2 3dh local would like to use your Camera Allow Block July 10 2015 Rev 1 3DHISTECH Ltd 30 54 CaseCenter 2 6 User s Guide 4 Slides and Folders 3 Move the object in front of the camera then click capture to capture image Slide name Automatic Slide deletion time W Never expire Organ X um per pixel Y pm per pixel na 750 250 E Capture July 10 2015 Rev 1 3DHISTECH Ltd 31 54 CaseCenter 2 6 User s Guide 4 Slides and Folders 4 The captured image is then displayed at the right pane of the window Recapture image if necessary Upload 5 Enter Slide name select Organ from the drop down list set deletion time and pixel size 6 Click 4 to upload macro image The image can be opened via InstantViewer CaseViewer and Pannoramic Viewer e Create Virtual Slide or Virtual Tray E With this feature a virtual slide or virtual tray can be created based on the original slide or Slides If you sel
34. idden for which you have no permissions at all For example if a folder name appears in black characters when it contains slides to which you have read and write access blue if the slides are read only and gray if the slides in the folder are hidden because the slides in it are not accessible 4 1 2 Folder operation buttons This section describes the buttons above the folder tree panel Folder operation buttons may be inactive depending on folder related permissions e Quick search folder 1 Enter a string of characters as a part of a slide block case folder name into the textbox then click 2 Amessage appears at the top of the window informing you about the number of found items related to your search o Items found using QuickSearch 5 x 3 To move between items click or July 10 2015 Rev 1 3DHISTECH Ltd 21 54 CaseCenter 2 6 User s Guide 4 Slides and Folders New folder fi Create new Folder Folder name Education Description Add User s Subfolders inherit the permissions of the parent folder A D Dep 1 amp DDep2 amp R Research fm F Frozen amp Prof Anton Aronson R Routine amp Prof Charlie Chang A Prof Brad Bronson PA DEE a a amp S Student Read only Add Group s Depariment 1 Department 2 amp Moderator Normal amp Restricted Read amp Write Read only E Cancel Accept Define properties of a new folder that you w
35. ide Annotations Annotation 1 Annotation 2 Annotation 3 Click for note n Annotation link Click this button if you want to share annotation link to another CaseCenter user who has access to the same slide on the server The user upon opening the link in the browser sees the slide magnified to the annotated area Annotation http ug2 3dh local CaseCenter index php SlidelID 92420792f5al8c5i0e3d651c a lebbf amp AnnotlID BFA 9A2F44 F22A 415E 838 C5 590 55AA D o Podr Sx 10x 20x 40x 11 Q 76 11 Zoom levels There are seven pre defined magnification levels Fit 2x 5x 10x 20x 40x and 1 1 control buttons in the bar If using the mouse wheel for zooming the current zoom level is displayed at the far right end of the bar Double click on the slide image to switch between levels Fit and 1 1 o Slide overview Shows a low resolution overview from the whole slide to help navigation The screened area is marked with a rectangle with gray border It allows fast navigation through the slide by clicking onto a certain point in the overview or panning with the rectangle You can use mouse wheel to zoom in or out on the slide image available also when using a touch monitor or a tablet July 10 2015 Rev 1 3DHISTECH Ltd 38 54 CaseCenter 2 6 User s Guide 4 Slides and Folders pu Label area Shows the label area of the slide Depending on scanner type this image can be flip
36. in the session click the Cancel button or you can start evaluating the slide or slides by clicking the Start Teleconsultation button July 10 2015 Rev 1 3DHISTECH Ltd 44 54 CaseCenter 2 6 User s Guide 5 Teleconsultation 5 5 Opening a slide via Teleconsultation In Pannoramic Viewer 1 Start Pannoramic Viewer 2 Connect to the 3DHISTECH Teleconsultation Server a To start Teleconsultation click um in the toolbar b Enter the server address and your authorization information in the dialog 3 On the Teleconsultation server tab folders and slides that you have been granted access to are displayed 4 Double click the slide that you want to open In CaseCenter After you opened the window of the selected Teleconsultation session you have been invited to and clicked the Start Teleconsultation button see section 5 3 Joining a Teleconsultation Session the following window appears Launch Application Send to Pannoramic Viewer Choose an Application Remember my choice for mview links Cancel As you can see Pannoramic Viewer is selected by default as the viewer application in which the slide will be opened If you would like to choose a different application click the Choose button and browse for it or click OK to continue with opening the slide with the default program When the Pannoramic Viewer is launched you are asked to write your name in the displaying window to connect to the Te
37. into the corresponding fields HTTPS connection can be established by selecting the Secure connection option Click OK when finished Connect to Teleconsultation Server Address 10 130 131 213 User Name kest Password a Secure connection E Cancel 2 2 Logging in to CaseCenter through CaseViewer 1 Launch CaseViewer 2 Select the CaseCenter panel from the startup page 3 Enter user credentials to access the designated server For more information on CaseViewer read CaseViewer Help Guide 2 3 Logging in to CaseCenter through the Web Interface 1 Type the URL of the CaseCenter the local System Administrator can assist you with the proper address in your web browser to access the CaseCenter AN Important The supported browser is Google Chrome Please do not use other browser types July 10 2015 Rev 1 3DHISTECH Ltd 13 54 CaseCenter 2 6 User s Guide 2 Connecting to CaseCenter 2 Enter your User name and Password and click login to access the page If a global cookie is set to ON by the administrator the login box may contain a checkbox to make the computer remember the user s login Upon selecting this option it is not necessary for the user to log in to the server again through the same browser before the cookie expires CaseCenter 25 Login sDHISTECH Free slots available 0 of 7 Login queue length 1 User name C Remember my login on this computer SDHISTECH Ltd Login AN Import
38. istique porta Fusce sodales aliquam lectus nec auctor Maecenas vulputate fringilla sapien in suscipit In hac hahitaceca nlataa dirtimect Maaranac andin anta ar narta arne Etiam imnardiot wulnutata arne anat mollie massa rammoadn id E Case 995 12 lt 1 gt Ba Socks 995 121 lt 6 gt 5 lUnidentified cases and slides a Education lt 1 gt Frozen Section HIS I Sa Lost and Found Slides a SEA r NELL g e 1 E i Routine Pathology 995 12_CD10 995 12_CD20 995 12_HE_l 2 995 12_Ki 67_1 995 12_Ki 67_1 995 12_CD10 995 12_CD20 995 12_HE_I 2 995 12_Ki 67_1 995 12_Ki 67_1 lymphatic organs lymphatic organs lymphatic organs lymphatic organs lymphatic organs IHC_CD10 IHC_CD20 IHC_KI 67 IHC_KI 67 2008 05 23 08 42 57 2008 05 23 08 50 12 2008 05 23 09 21 00 2008 05 23 09 26 18 13 10 18 09 48 39 686 87 MB 829 91 MB 578 91 MB 717 49 MB 737 B su_local su_local su_local su_local Research hi hi hi New v It consists of the following interface elements e Folder Tree Panel 1 including a tree view of the server content and structure and folder operation buttons e An informational region related to the actual folder case block its name and description together with the included slides and their attributes on the Folder Content Panel 2 e Action Field 3 with several additional options for searching through ordering and filtering the content 4 1 Folder Tree Panel The tree structure of the server can be seen
39. leconsultation session You can start working on the slide after you logged in Create connect to a teleconsultation group Your nick name it must be unique in the teleconsultation group Cancel July 10 2015 Rev 1 3DHISTECH Ltd 45 54 CaseCenter 2 6 User s Guide 5 Teleconsultation 5 6 Working Simultaneously on a Slide in an Online Teleconsultation Session 1 The Host must ensure that all participants can access the slide Note that participants cannot modify the slide or take over the control 2 In CaseCenter on the Teleconsultation panel select the session and click Start Teleconsultation 3 Enter your nick or name into field of Create connect to a teleconsultation group window 4 If connected to server select the slide you want to share with others either from the folder tree on Teleconsultation server tab in Pannoramic Viewer or in the Teleconsultation window in CaseCenter then open it 5 Click the button in the slide window in Pannoramic Viewer 6 The slide is displayed in Pannoramic Viewer for all participants Offline telecons amp a2 E e La ax Ns reni alcoli fx ETTI EY EEN Magniication 023 Progress INNI 5000 um 400 z C Preview C Tracking history Preview and tracking history Delete Tracking History AN Warning If the Host tries to enable a slide that has not been uploaded to CaseCenter Teleconsultation starts uploading the s
40. lide The upload however might take time because digitized slides are usually large files often 500MB 1GB or larger Uploading a 1GB slide over a 2000 kilobits sec connection requires more than 70 minutes If uploading is started during Teleconsultation the waiting period for the slide might be unmanageably long and the background upload process might also reduce the speed of Teleconsultation July 10 2015 Rev 1 3DHISTECH Ltd 46 54 CaseCenter 2 6 User s Guide 5 Teleconsultation 7 It is possible to work with several slides at the same time Participants always see the same slide s and the same part of the active slide as the Host 8 The Host can work with the slide for example move around on it to check its parts as in Pannoramic Viewer without Teleconsultation 9 The Host should take into consideration that Pannoramic Viewer might be displayed with different resolutions on other participants screens The best Teleconsultation result can be achieved with screen resolutions that do not differ significantly from each other 10 Participants can take over from the Host click Request control in the slide toolbar A request is sent to the Host The Host can cede or deny control to the participant The name of the user who moderates the session is shown in red in the participant list in the message box 11 The Host and the participants can also exchange comments via the chat tool 12 To quit a Teleconsultation session
41. on this panel where the actual folder is presented by blue background The number of the containing slide is written after the folder name in brackets Hierarchically the Case is a sub level element within a folder and the Block is a sub level element of a Case You can create several cases within a folder and several blocks in a case Folder may contain slides and cases case can contain slides and blocks but only slides can be stored within a block The number of elements within a folder is specified in a bracket at the end of the folder name July 10 2015 Rev 1 3DHISTECH Ltd 20 54 CaseCenter 2 6 User s Guide 4 Slides and Folders 4 1 1 Folder Color Markings User access rights are presented in different colors of folders in the tree panel Quick search folder fl al Hospital A amp y INew Cases Unassigned a E Case 198 08 E Case 995 12 lt 1 gt Block 995 12 I lt 5 gt Unidentified cases and slides Education Frozen Section B HIS Lost and Found Slides A Research C Routine Pathology sl fl fal Stl Acad Kal fa Folder color marking and the tasks according to the different access rights are listed below e Black Folder Read and Write access e Blue Folder Read only access e Gray No access permission but a sub folder can be visible if you have read only or read write access rights for that specific sub folder case or block Folders cases or blocks are h
42. ped upside down With the icon the label image can be flipped by 180 Slide information can be displayed by clicking the ry icon Slide information is displayed in a pop up window Slide properties Optical parameters Objective name Plan Apochromat Objective magnification 20x Camera adapter magnification 1x Optovar magnification 1x Camera type Zeiss ICc1 or Marlin F146C Micrometer pixel X 0 2325 Micrometer pixel Y 0 2325 Scan information Scan duration HH MM SS 00 20 01 File size Unknown Slide dimensions in pixels 78336 x 113408 Scanned field of view count 5797 Image parameters Image compression Yes Image file format JPEG Quality factor 80 System informations Access protocol HTTP o Available color channels on a fluorescent slide DAFI Fluorescent slides contain individual channels for each fluorescent signal The panel at the bottom of the window represents the available fluorescent channels of the slide Click the label to turn a channel on or off o Hotkeys label area n slide overview O 1 2 3 4 5 represent the magnification levels from fit to screen to 40x To open a slide either in Pannoramic Viewer or in InstantViewer click on the thumbnail image of the Slide To edit slide attributes click the corresponding Z icon at the right side of the panel July 10 2015 Rev 1 3DHISTECH Ltd 39 54 CaseCenter 2 6 User s Guide 4 Slides and Folders 4 3 CaseView
43. ps Move the cursor over the menu selector to see the list of options e Slides amp Folders Browse the folder structure of the server e Teleconsultation Opens the Teleconsultation window e Share View shares e Search Search for slides or folders e Users amp Groups Show users and groups NOTE Only those tabs are visible that are selected to be accessible for the specific user type July 10 2015 Rev 1 3DHISTECH Ltd 19 54 CaseCenter 2 6 User s Guide 4 Slides and Folders 4 Slides and Folders Upon loading the CaseCenter web interface the Slides amp Folders window is displayed by default 2 6 RTM Mr Doe John n d CaseCenter 2 6 1 51798 998 999 CaseCenter 00 28 minutes left Change profile Ce Slides amp Folders Quick search folder ne Quick search Slide 3 View type Order by Open Slides in sb u z Ls le Ge Slide tray v Image Type Pannoramic Viewer i j 12 Block 995 121 a Hospital A Micro description of Block I Lorem ipsum dolor sit amet consectetur adipiscing elit Cras purus eros hendrerit a tincidunt vel ullamcorper nec neque Donec egestas Eq New Cases Unassigned auctor nulla tincidunt porta felis scelerisque id Nam tellus enim placerat ut accumsan id sodales sed leo Pellentesque vestibulum pretium leo vitae adipiscing Aliquam E Case 198 08 lt 3 gt nec nibh vitae tellus sollicitudin iaculis Mauris elementum tr
44. r Slide size and SU name fields cannot be edited Slide can be opened from the Edit Slide window by clicking on its thumbnail image 4 2 2 Slide actions MESE k ako ho hohe Bo ee Order by Open Slides in AMANDMA DPD mm ire E 2 FE Case 198 08 Pw The elements of the action bar are as follows from upper row left to right if Default view is selected e Tick the checkbox to select all folder items for further operation e Quick search Slide Enter the text or character string you are looking for in the search field Search results are listed automatically in accordance with the entered text e Duplicate Select slides then after clicking 5 the folder tree is displayed in the Duplicate Slide window Click the destination folder case or block and the slide s will be copied to that specific container by clicking the Accept button Duplicate Slide x Select a destination folder Sy Hospital A 5 New Cases Unassigned E 10301 07 lt 5 gt SES C Education C Frozen Section C Research C Routine Pathology Ca TB TMA lt 1 gt amp Cancel Accept July 10 2015 Rev 1 3DHISTECH Ltd 27 54 CaseCenter 2 6 User s Guide 4 Slides and Folders A progress bar can be seen in the Slide name field displaying the percentage of completion G 195 08_G_ colon Toluidin Blue 2008 04 23 17 57 18 40 9 MB su_local II AN Important Duplication physic
45. r scripts CAUTION For research and education uses only not for use in diagnostic procedures This product has not been approved or cleared as a medical device by the U S Food and Drug Administration nor any other regulatory authority The data and images obtained or viewed using this product are not intended for clinical or diagnostic use For performance evaluation only the performance characteristics of this product have not been established July 10 2015 Rev 1 3DHISTECH Ltd 4 54 CaseCenter 2 6 User s Guide Third Party Disclaimer LibTIFF TIFF Library and Utilities 3DHISTECH Ltd is not liable for damage of whatever nature including but not limited to general or specific damage indirect damage consequential damage or incidental damage including damage resulting from lost profits interruption of business loss of business information pecuniary loss or similar damage that stems from or is associated with the incorporated part of this Product that is made by Silicon Graphics Inc THE SOFTWARE IS PROVIDED AS IS AND WITHOUT WARRANTY OF ANY KIND EXPRESSED IMPLIED OR OTHERWISE INCLUDING WITHOUT LIMITATION ANY WARRANTY OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE IN NO EVENT SHALL SAM LEFFLER OR SILICON GRAPHICS BE LIABLE FOR ANY SPECIAL INCIDENTAL INDIRECT OR CONSEQUENTIAL DAMAGES OF ANY KIND OR FOR ANY DAMAGES WHATSOEVER RESULTING FROM LOSS OF USE DATA OR PROFITS WHETHER OR NOT ADVISED O
46. ramic Viewer on your computer E 2 To connect to the CaseCenter server click im in the toolbar July 10 2015 Rev 1 3DHISTECH Ltd 11 54 CaseCenter 2 6 User s Guide 1 About CaseCenter 3 Enter server address and your authorization information User name and password into the corresponding field HTTPS connection can be established by selecting the Secure connection option Click OK when finished NOTE If you encounter a problem contact the CaseCenter administrator Connect to Teleconsultation Server US 10 130 131 213 x User Name test Password A Secure connection Cancel 4 Ensure that the slide is visible in the navigation tree on the Local tab in Pannoramic Viewer If the slide is not visible add the containing folder to the navigation tree a To open the slide click in the toolbar b Browse for the folder that contains the slide c Click Add Folder then click Close 5 Right click the slide that you want to upload and then select Upload Slide to Teleconsultation Server 6 Set the properties for the copy of the slide to store on CaseCenter 7 Click Start Upload July 10 2015 Rev 1 3DHISTECH Ltd 12 54 CaseCenter 2 6 User s Guide 2 Connecting to CaseCenter 2 Connecting to CaseCenter 2 1 Connecting through Pannoramic Viewer 1 Launch Pannoramic Viewer on your computer 2 To start Teleconsultation click Om in the toolbar 3 Enter server address and user credentials
47. rays or slides stained with fluorescent probes with a 3DHISTECH scanner microscope for example with Pannoramic SCAN 150 For more information on Pannoramic microscopes see product brochures or the current issues of user s guides of Pannoramic scanners 2 The Pannoramic scanner microscope creates digitized slides that can be saved on a local computer connected to the scanner or if the ScanToServer application is installed the slides can be uploaded through the scanner software directly to the CaseCenter server where slides can be evaluated shared and you can also create Teleconsultation session to discuss specific cases with pathologists 3 Slides can be opened from the local computer or the CaseCenter via Pannoramic Viewer you can inspect the local slides and you can create annotations on them to mark interesting areas July 10 2015 Rev 1 3DHISTECH Ltd 8 54 CaseCenter 2 6 User s Guide 1 About CaseCenter Pannoramic Viewer is a platform for the following applications called modules e With the Teleconsultation module you can upload slides to a dedicated server and share them with other Pannoramic Viewer users to request their analysis e With the TMA module you can view and analyze slide sets in which each slide is a cut from a tissue microarray Combined with the TumorBoard module the TMA module provides you with a powerful tool to perform research scale analyses on digital slides e With the TumorBoard module you
48. rerit a tincidunt vel ullamcorper nec neque amp New Cases Unassigned Donec egestas auctor nulla tincidunt porta felis scelerisque id Nam tellus enim placerat ut accumsan id sodales sed leo Pellentesque vestibulum s E Case 198 08 pretium leo vitae adipiscing Aliquam nec nibh vitae tellus sollicitudin iaculis Mauris elementum tristique porta Fusce sodales aliquam lectus nec auctor E Case 995 12 lt 1 gt pi ee a Sa Af Block 995 12 I lt 5 gt iv F F Unidentified cases and slides Education Frozen Section HIS Lost and Found Slides Research Routine Pathology 995 12 CD10 995 12 CD20 995 12 HE _I 2 995 12 _Ki 67_1 995 12 Ki 67_1 995 12 CD10 995 12 CD20 995 12 HE _I 2 995 12 _Ki 67_1 995 12 _Ki 67_1 lymphatic organs lymphatic organs lymphatic organs lymphatic organs lymphatic organs IHC_CD10 IHC_CD20 HE IHC_KI 67 IHC_KI 67 2008 05 23 08 42 57 2008 05 23 08 50 12 2008 05 23 09 21 00 2008 05 23 09 26 18 2013 10 18 09 48 39 sso New v 3 1 User Panel At the top right corner of the main application screen there is a panel to display the name and type of the user currently logged in The time left before you are logged out due to inactivity is displayed below the user name _ Mr Doe John 00 21 minutes left Change profile User type is presented by the color of the avatar A Moderator A Normal amp Restricted amp Public share July 10 2015 Rev 1 3DHISTECH Lt
49. ser s Guide 5 Teleconsultation Each of the participants receive an invitation that is visible under the TC invitations panel of the Teleconsultation menu If the system is properly configured also a message will be sent to a participant s e mail address whenever a Teleconsultation session is created or there is any modification regarding the session 5 4 Joining a Teleconsultation Session In the TC Invitations window there is a list of Teleconsultation sessions you have been invited to Select the one you want to participate in by clicking on the list item x x Mr Smith Bill CaseCentero Pe CaseCenter x Mr Smith Bi 00 30 minutes left i i I Change profile gt Teleconsultation 7 TC invitafione Quick search Title HostofTeleconsultation O Start date Expiration date Teleconsultation_01 Mr Doe John 2015 04 3009 00 2015 05 04 09 00 The pop up window displays all the necessary information regarding the session such as start date and expiration date of teleconsultation description subject slides or projects and attendees Teleconsultation details Teleconsultation_02 Start date 2012 04 23 10 00 Expiration date 2012 05 01 10 00 Description _ Subject slides Attendees 2D Estrogen il ai Slide 10301 07_ER_1 breast aa John Doe johndoe A 2D a Hematoxylin Slide 10301 07_HE_I 1 breast ae Cancel Start Teleconsultation To close the window without participating
50. the Search button You may narrow the list by adding other criteria such as Date From or Date To Organ Staining Status or Service Unit CaseCenter CaseCenter ALIA 998 993 Search Mr Doe John 00 29 minutes left Change profile v A Text Organ Status Save as All organ All status Save Q Search Date From Date To Staining Service Unit Saved searches FE v All Service Units Notset Delete Reset f View type Open Slides in Slides i gt 5 x lah ie id LE Le Simple InstantViewer Folders 91 Label Area na n Preview Image Image Type Slide name Barcode Folder Path Organ Staining Scan Date Status Slide size SU name Edit le 2D Slide 1014B12345 12 HE 10 1014B12345 12 HE 10 Hospital A HIS Ankara Biopsy 14 1 2 3 4 1014B12345 12 stomach HE Semon 13 72 MB su_local A LS 2008 05 23 A fe 2DSlide 995 12_HE_I 2 995 12_HE_I 2 Hospital A INew Cases Unassigned Case 995 12 Block 995 12 lymphatic organs HE sa 578 92MB su_local A 24 IL July 10 2015 Rev 1 3DHISTECH Ltd 49 54 CaseCenter 2 6 User s Guide 8 Users amp Groups 8 Users amp Groups The Users amp Groups window displays information regarding the data of registered users and groups created by administrators The Users and Groups information is separately displayed on two different panels To select a user or group in order to see their data scroll down the list in this windo
51. the select all checkbox at the column header to select multiple files e Multiple files can be downloaded by clicking the button or click the icon to download a single attachment e Click View in browser to open attachment in a browser window The URL of the file can be shared e To delete attachment s click the button to batch deletion or the icon to delete a single file e Click Yes to delete selected file s from the list July 10 2015 Rev 1 3DHISTECH Ltd 36 54 CaseCenter 2 6 User s Guide 4 Slides and Folders e Open Slides in Choose Pannoramic Viewer or InstantViewer as the default slide viewer application in which the selected slides can be opened If you select InstantViewer as the application for opening slides the slide image is displayed in a new tab in your browser gt GC D ug2 3dh local CaseCenter index php UserID 96c64ce8fald0582edff8439ada4a9a8 The following functions are available for you o Pan mode This mode is active by default and it enables the dragging the slide image in the window available also when using a touch monitor or a tablet 28 Create Annotation Create an annotation of your like on the slide after selecting the desired type July 10 2015 Rev 1 3DHISTECH Ltd 37 54 CaseCenter 2 6 User s Guide 4 Slides and Folders o Annotation list Annotations on the slide are listed here Click a list item to display its location on the sl
52. to remember to previous session it may happen that you cannot log in again because of licensing issues the maximum number of user licenses is reached Modify browser settings of Google Chrome as follows e Click at the top right corner of the Chrome window e Select Settings menu from the list e Select Continue where you left off option at On Startup section 3 1 1 Managing a CaseCenter User Account Your user account user name and password is created by the CaseCenter administrator There are no restrictions on how many slides you can upload to the CaseCenter server assuming that there is still enough storage place on the server AN Important You might not be able to change the password assigned to you by the administrator who enables or disables password resetting when your account is created If you have trouble with resetting your password contact your CaseCenter administrator 3 1 2 Changing a User Password If you are allowed to change your password do the following 1 Open the CaseCenter main page in your web browser 2 Enter your User name and Password and click login 3 Click Change profile in the User panel and modify the password in the Edit user window see this section above July 10 2015 Rev 1 3DHISTECH Ltd 18 54 CaseCenter 2 6 User s Guide 3 CaseCenter Main Application Screen 3 2 Menu Options Ls Slides amp Folders 7 gt Teleconsultation Share d Search a Users amp Grou
53. w Also you can search for users or groups to narrow the search results enter the text in the Quick search text box Each column can be ordered by clicking the column header Users who currently are logged in are displayed with active avatars in the User column 2 6 RTM Mr Doe John CaseCenter 2 6 1 51798 998 999 CaseCenter 00 27 minutes left Change profile IDHISTECH Sa Users amp Groups User amp Username User title Given name Family name User last logged in at User level User type Details 1 ry amp ijohndoe Mr John Doe 2015 04 30 13 40 25 amp Moderator User CaseCenteruser amp awest Abraham West amp Public Share User CaseCenteruser amp a billsmith Mr Bill Smith 2015 04 30 10 28 56 Normal User CaseCenteruser amp A janedoe Ms Jane Doe amp Normal User LDAP user a profc Prof Cc Cc 2013 04 23 04 01 08 amp Restricted User CaseCenteruser NOTE Imported LDAP users are displayed with blue background To access user or group data click the amp or the amp button in the Details column Userdata x Group data User title Family name Group name MIT Doe Department 1 Given name Select User A D Dep 1 E mail i R Research john doe sdhistech com Other Contact Specialties User and group data can be edited by administrators only If you find something that is needed to be modified contact your administrator directly July 10 2015 Rev 1 3DHISTECH Ltd 50 54

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