Galaxy ® CO2 Incubators
Contents
1. 4 amp 5 Galaxy 48 liters 1 7 cu 6 amp 7 Galaxy 14 liters 0 5 cu 1 8 e 9 Stem Cell amp IVF Applications 9 Options amp Ordering Info 10 amp 11 Specifica ONG 12 VEN New Brunswick anepoendeod comgpany GALAXY THE RIGHT CO INCUBATOR FOR YOUR LAB NBS Galaxy incubators are offered in a range of three sizes and two models with an unrivaled number of options All Galaxy incubators feature SIX SIDED DIRECT HEATING PROFILE Pioneered in Galaxy incubators the unique direct heat profile gently bathes the cells in a consistent atmosphere through gentle convection This system guards against wide fluctuations in temperature and CO that can shock cells as seen in traditional forced air culture systems FANLESS DESIGN Galaxy incubators pioneered elimination of conventional fans replacing them with our unique heating profile which sets up a gentle circulation of air By removing the fan Galaxy incubators have eliminated a classic source of repeated contamination allowing the entire incubator including upper shelf to be utilized while maintaining uniformity In addition since there is no fan there is no need for an expensive internal HEPA filter that needs to be replaced frequently IR SENSOR standard in all Galaxy models is our unique InfraRed IR CO sensor Thi2. P0628 7211 Control Valve amp Flow Indicator for 20 Liter Canister P0628 6061 Calibration Gas 596 105 Liter Disposable Canister P0628 7210 P0628 7221 Two Stage CO2 Regulator Two Stage N2 Regulator CO Supply Line HEPA Filters 2 CO2 In line Pressure Regulator Cylinder Auto Changeover Controller Auto Zero HEPA Filters 5 CO2 Gas Analyzer Kit Spare CO2 Gas Analyzer Tubes 10 P0628 5040 P0628 5040 P0628 5050 P0628 5050 P0628 6150 P0628 6150 P0628 6831 P0628 6831 P0628 6832 P0628 6832 P0628 7211 P0628 7211 P0628 6061 P0628 6061 P0628 7210 P0628 7210 P0628 7221 P0628 7221 P0628 6390 P0628 6170 P0628 6241 P0628 6180 P0628 6251 P0628 7200 P0628 6270 P0628 5091 Accessories Electronics amp Software BioCommand SFI Software M1291 0054 M1291 0054 M1291 0054 M1291 0054 M1291 0054 Part numbers subject to change without notice Additional incubator configurations are also available Ordering them or ordering custom options will affect delivery and shipping Not all options are compatible Ask your NBS Sales Rep for quotation All models are 50 60 Hz units t For Reusable 105 liter cylinder 9 Please check availability before ordering Cooling option cannot be combined with High Temperature Disinfection options Electronic CO2 Gas Analyzer 0 3 liter min Flow Regulator w pressure Gauget Accessories Shelves Pans amp Stacking Stand Multi Position Shelf Rack Additional Shelf non perforated Additional
3. 00 CO48R 230 1000 With 1 19 Control 120V CO170R 120 0200 CO48R 120 0200 239 __ CO14S 120 0200 CO14S 230 0200 With 1 19 Control 230V CO170R 230 0200 CO48R 230 0200 With High Temp amp 1 19 Control 120V CO170R 120 1200 CO48R 120 1200 With High Temp amp 1 19 O Control 230V CO 170R 230 1200 CO48R 230 1200 Additional Factory Installed Options P0628 6280 O2 Control 0 1 19 O2 Control 1 9596 P0628 5260 P0628 5340 P0628 5340 P0628 6300 P0628 6210 P0628 5410 P0628 5400 P0628 6810 P0628 6800 P0628 5540 Standard Active Humidification 2 P0628 5651 Standard Building Management System Relays Single Inner Glass Door oom o om Split Inner Doors 2 P0628 6780 P0628 6781 P0628 6820 P0628 5560 P0628 5612 P0628 6780 Jer UN _ P0628 5010 P0628 5010 P0628 5020 P0628 5020 P0628 5030 P0628 5030 P0628 5000 P0628 5000 P0628 5060 P0628 5060 P0628 5060 P0628 5060 Split Inner Doors 4 Split Inner Doors 8 Humidity Alert Package Display and Alarm Internal Sealed Power Supply IP66 Copper Chamber amp Chamber Fittings Accessories Gas Management amp Analysis P0628 5010 P0628 7220 P0628 5020 P0628 5030 P0628 5000 P0628 5060 P0628 5040 P0628 5050 P0628 6150 Electronic CO2 amp O2 Gas Analyzer P0628 6831 Electronic CO2 amp O2 Gas A w amp RH meas P0628 6832 Calibration Gas 596 20 Liter Disposable Canister
4. 33 Fax 44 0 1727 835 666 sales nbsnv sa be nbschcQonline sh cn bioinfo nbsuk co uk www hbsuk co uk THE NETHERLANDS RS BIOTECH UK 31 0 24 3717 600 A New Brunswick Scientific Co Fax 31 0 24 3717 640 44 0 1294 204800 salesQnbsbv nl Fax 44 0 1294 204801 service rsbiotech com D 15K 3 09 XCP PDFa www rsbiotech com
5. GALAXY DIRECT HEAT CO INCUBATORS EXPANDING THE CELL CULTURE UNIVERSE WITH SUPERIOR PERFORMING 14 170 LITER SYSTEMS OA AC gt i a Ec ca E 9 F K Y New Brunswick aneppendorf company Since 1991 Galaxy CO incubators have offered researchers and clinical labs a reliable and user friendly system for culturing cells Now the Galaxy line has been improved to offer even more standard features better performance and a wider range of options Galaxy CO Incubators were originally developed by RS Biotech which is today a part of New Brunswick Scientific NBS These incubators were the first to offer a direct heat fanless design transforming the way cell culture is accomplished and making traditional water jacketed incubators a rusty relic of the past By providing more incubation capacity in a smaller foot print with more options and a significant decrease in contamination risk compared to water jacketed systems Galaxy CO incubators are easier to maintain setup and utilize while providing superior performance These elements have made Galaxy systems a favorite among discerning scientists in in vitro fertilization IVF stem cell research as well as traditional cell culture Galaxy incubators meeting your cell culture demands today and into the future Table of Contents About Galaxy Incubators 2 amp 3 Galaxy 170 liters 6 0 cu ft
6. Shelf perforated Standard P0628 6241 P0628 6251 P0628 6270 P0628 6490 P0628 7260 Lower and Upper Stacking Frame with casters Lower Frame with casters Upper Stacking Frame Wall Mounting Frame for 2 Incubators m Lj d Galaxy Specifications 4 53 T Galaxy 170R amp S Galxy48R amp S 170 liters 6 0 cu ft 48 liters 1 7 cu ft 14 liters 0 5 cu ft Temperature 5 C above ambient to 50 C Management Control Stability Uniformity 0 2 20 0 2 20 0 2 20 Management Control 0 1 0 1 0 1 Stability 0 2 0 2 Uniformity 0 1 0 1 setpoint 0 7 minute 0 7 minute gt 0 7 minute Connections 6mm tubing 6mm tubing Gas Service Pressure 0 35 bar 5 psi 0 35 bar 5 psi 0 35 bar 5 psi Humidity Reservoir Removable stainless pan Removable stainless pan Removable stainless pan 0 Volume 25 liters 03 liters RH 37 up to 95 Normal 90 95 gt 90 at 37 C Dimensions per Shelf 9 51 9 x 42 6 cm 20 4 x 16 8 35 1 x 26 1 cm 13 8 x 10 3 22 0 x 18 4 cm 8 7 x 7 2 Shelves Provided Adjustability R 8 position S 4 position 4 position Chamber mm 540 x 451 x 693 mm 401 x 308 x 401 mm 233 x 208 x 294 mm Chamber inches 21 3 x 17 8 x 27 3 15 8 x 12 1 x 15 8 92 x82 x 11 6 External mm 685 x 677 x 848 mm 484 x 475 x 648 mm 313 x 285 x 454 mm External inches 27 x 26 7 x 33 4 19 1 18 7 x 25 5 12 3 x11 2 x 17 9 Shipping Co
7. W COOLING SYSTEM Available on the 170 R e Allows studies at or below ambient tempera ture e Effectively cools to 10 C below ambient temperature e Redesign offers an efficient and uniformly cooled chamber BUILDING MANAGEMENT SYSTEM BMS RELAY Available on all models e Relay for integration with building alarm system COPPER CHAMBER Available on 170 R and S e Oxidizing copper copper plated chamber and chamber fittings provide added contamination protection SPLIT INNER DOORS Available 170 R amp S and 48 R amp S e 4 or 8 Split inner glass door options available on 170 R amp S models e 2 Split inner glass door option available on 48 R amp S models e Offers enhanced cham ber temperature unifor mity and reduced gas consumption e Maintains easy access to samples BIOCOMMANDS SFI Available on all models e NBS data logging and control software designed specifically for our CO Incubators e Provides historical data logging and report generation to local computer and for multiple units e Connects through RS 232 port E um E H x Ae PX New Brunswick imn eppendert company a E 2 HG gt 170 5 Standard 120V CO170S 120 0000 CO14S 120 0000 Standard 230V CO170S 230 0000 CO14S 230 0000 With High Temp Disinfection 120V CO170S 120 1000 Galaxy Incubator Model 170 R With High Temp Disinfection 230V CO170R 230 1000 CO170S 230 10
8. alarm relay contacts tion Is required It is also available with high temperature disinfection option providing an added level of reassurance against contamination Copper chamber and interior EATURES e Direct heat 170 liter 6 0 cu ft on a minimal footprint e IR sensor with automatic auto zero programmable function to ensure accurate calibrated measurements Seamless chamber 25mm Access port Perforated shelving ithe E E Sealed inner glass door for atmosphere conservation e RS 232 Communications port r Stackable up to two units high gi Large volume humidification pan with dedicated independent heater e Quick and comprehensive chamber cleaning made effortless e HEPA filtration of gas supply inlets to minimize contamination risk 4 position shelving rack with 4 shelves il hs Rs Galaxy 48 Lite Personal Size Incubators provide the luxury of owning a singles user personal sized 48 liter 1 7 cu ft incubator They offer the same standard features as the larger 170 liter models including fanless design to allow for maximum capacity Galaxy 48 models easily fit on a benchtop for GALAXY 48 R Galaxy 48 R incubators feature an integrated and heated outer door window to allow viewing your cultures with out compromising the culture environment They are ideally s
9. elines described in your user s manual Q Are there any parts which should be regularly renewed on my Galaxy A Yes Replace the CO supply line HEPA filter and auto zero HEPA filter at least once per year Auto zero filter used in R models only Q Do you offer an incubator that can be run at around or below the ambient temperature of my lab A Yes we can offer the Galaxy 170 with cooling option The cooled incubator can be used normally at 37 C or other temperature above ambient and also works at temperatures as low as 10 below ambient Q I see that Galaxy 170 incubators have a door hinge on the left side Can I order it hinged on the right A Yes but we apply a surcharge for this non standard arrangement and delivery time will be longer STEM CELL APPLICATIONS Stem cell research is advancing at a rapid pace and recent studies have shown that for many cell types an environment closer to the physiological oxygen concentrations 2 596 the cells normally encounter in vivo can result in e smaller cells with reduced complexity e reduced spontaneous differentiation e increased clonogenicity e reduced spontaneous chromosomal aberration frequencies e extensive propagation of specialized clonal derivative cells Galaxy CO incubators offer a direct heating system which gently bathes cells in warm convected air In addition we offer highly regulated and environments with the ability to closel
10. incorporation in workstations and laminar hoods e Seamless fanless chamber design e RS 232 and 25mm access port standard Low gas consumption Perforated shelving to allow for faster recoveries External supply line HEPA filtration OPTIONS See page 10 for details 1 19 control e Single inner glass door e BMS alarm relay contacts Using Galaxy s advanced 1 1996 oxygen control option stem cells can be cultured in near to in vivo conditions avoiding cell differentiation It is ideal for stem cell and IVF applications including oocyte collection and preparation pre implantation diagnostics embryo transfers and sperm preparation When adding the 1 19 oxygen control option the 14 S becomes a small hypoxic incubator consuming a minimal amount of nitrogen 45 4 cm 17 9 Rapid recovery of temperature and RH after door opening is facilitated with our unique new perforated shelf design alized Applications FREQUENTLY ASKED QUESTIONS ALL MODELS Q am hesitant to move from a water jacketed incubator to a direct heat system Why should I switch A While water jacketed WJ incubators have in the past been suitable for generalized cell culture they truly are an outdated technology WJ incubators are bulky often taking up valuable lab space offer less capacity in relation to that space have lower performance and control are difficult to maintain a
11. me superior performance as 48 R models The S Series use an easily read LED interface and includes an integrated viewing window standard 25mm access port and RS 232 communications package They are ideal for laboratories with limited space to house large incubators or for standard cell culture applications where the larger 170 liter capacity systems are not required FEATURES e Small footprint with mid sized capacity Seamless chamber Fanless design 2n aac y TN CA all Cdoy lO UoG e 25mm access port e RS 232 port User friendly LED display OPTIONS see page 10 for details e BMS management system relays Two split inner glass doors Galaxy 14 Lite Micro Size Incubators Galaxy 14 S is a unique mini sized 14 liter 0 5 cu ft incubator originally designed for but not limited to in vitro fertilization IVF work Its compact size is ideal for individually support ing and isolating cultures for specific patients or samples The 14 S easily fits into IVF work stations and under laminar flow hoods for complete minimization of contamination risk GALAXY 14 S The 14 S provides an LED interface with RS 232 and 2bmm access port as standard A small footprint yet spacious chamber allows for specific applications to be carried out in isolation from general cell culture ensuring assay validity FEATURES Convenient benchtop size and footprint Size allows for
12. nd do little to prevent contamination High temper ature disinfection is also not possible in WJ designs The direct heat design provides an innovative solution to these issues and is ideal for culture in today s laboratory Q am interested in the high temperature disinfection HTD option for periodic preventative maintenance What can you tell me about its effectiveness A The Galaxy has a 120 C 4 hour HTD cycle that has been shown to be very effective in controlling contaminants See www nbsc com galaxy for downloadable report Sterility is a function of temperature and time in these cases The CO sensor does not have to be removed from the unit making running the HTD cycle efficient rapid and effective Q may want to add the O control option to my Galaxy incubator at a later date Can this be retrofitted A The O control feature cannot be field retrofitted and is only factory installed We suggest ordering it at the time of purchase to provide a single incubator that will meet your requirements for many years to come Q Can I externally data log my incubators A Yes all new Galaxy incubators come with an integrated RS 232 port that allows data to be logged remotely using BioCommand SFI software How should I clean disinfect my Galaxy incubator A Currently the only acceptable disinfecting agent is a solution of 70 Isopropanol isopropyl alcohol and 30 distilled water Carefully follow the cleaning guid
13. ntainer mm 830 x 830 x 1100 mm 630 x 630 x 920 mm 580 x 440 x 400 mm Shipping Container inches 32 7 x 32 7 x 43 3 24 8 x 24 8 x 36 2 22 8 x 17 3 x 15 7 Voltage 120 V amp 220 240 V 50 60 Hz 100 120 V amp 220 240 V 50 60 Hz 500 W 700 W Power High Temp Option 1000 W N A Consumption to 37 C lt 0 08 kWh lt 0 06 kWh Net 90 kg 198 Ibs 32 kg 71 Ibs 12 5 kg 28 Ibs Shipping 115 kg 254 Ibs 50 kg 110 Ibs 18 5 kg 41 Ibs Warranty Coverage Comprehensive 2 year warranty on parts and labor t Maintenance Contracts Ask your NBS sales representative about our extended maintenance contracts Certification CE Certified Shelves Specifications subject to change without notice All tests performed at ambient temp of 22 C the incubator set at 37 C and 596 CO Recovery data follows a 15 second door opening Shelf dimensions are shown wide x deep x high Galaxy 14 S Dimensions are for single unit When double stacked allow 313 x 285 x 887 mm 12 3 x 11 2 x 34 9 t sensor has a one year warranty NEW BRUNSWICK SCIENTIFIC A culture of innovation Di JA e New Brunswick USA Headquarters Box 4005 Edison NJ 08818 4005 bioinfo nbsc com an eppendorf company 800 631 5417 e 1 732 287 1200 Fax 1 732 287 4222 www nbsc com UNITED KINGDOM BELGIUM CHINA Free Tel 0800 581331 32 0 16 56 28 31 86 21 64845955 64845966 44 0 1727 853 855 Fax 32 0 16 57 27 53 Fax 86 21 648459
14. ontrol options 1 231995 1 9595 or 01 19 Specialized IVF service and support New Brunswick has a dedicated global network of specialist IVF distributor partners who have in depth knowledge and specialist technicians who can respond immediately and restore correct function to your incubator With the many unique advantages that Galaxy CO incuba tors offer together with unparalleled support and service it is not surprising that they have become the incubators of choice in IVF clinics Galaxy Option CUSTOMIZE YOUR INCUBATOR WITH THESE OPTIONS HIGH TEMPERATURE DISINFECTION Available on the 170 R amp S and 48 R models e 120 C 4 hour cycle e Convenient and simple operation Sensor remains in the chamber e Ensures a clean and disinfected environment for cell culture CONTROL Available on the 170 R 48 R and 14 S e Up to three levels of control options e 1 19 for most common hypoxic applications Active 0 1 19 for more stringent oxygen requirements e 1 95 for hyperoxic and hypoxic incubation e Ideal for Stem Cell Oncology and IVF studies NEW ACTIVE HUMIDIFICATION SYSTEM AHS Available on the 170 R e Rapid humidification of the chamber RH e User defined humidification settings to 95 e Non condensing humidity e Ideal for low sample volume and microtiter plate applications e External UV disinfection of humidified atmosphere NE
15. r added details Galaxy CO incubators come with a wide variety of options allowing customization to meet your exact requirements and level of sophistication With High Temperature Disinfection HTD three levels of control and new humidification options there is a Galaxy incubator for every application NEW FEATURES e 25mm Access Port Standard Available for adding instrumentation or additional probes e RS 232 Port Standard For communication and external instrument logging Perforated Shelves The unique design of the perforated shelving system optimizes temperature and especially RH recovery to minimize the effects of door openings and closings e Innovative Sealed Inner Glass Door Available on 170 liter models the new sealed inner glass door system allows viewing access to the samples while maintaining complete sample and environmental integrity This system is designed to minimize costly and consumption and to provide optimal sample stability and uniformity throughout the culturing process n Vig B e Ws Galaxy 170 Lifer Full Size Incubators Galaxy 170 R amp S Series Incubators offer large capacity 170 liters 6 0 cu ft cell culture envi ronments with a minimal footprint These incu bators maximize capacity while minimizing valu able laboratory space The fanless design allows for more usable space inside the chamber The GALAXY 170 R Full featured R Series inc
16. reens trend graphs and diagnostics CONTROLLER The Series CO incubator s advanced display screen and controller allow for comprehensive and rapid analysis of real time and historical conditions e 72 hour continuous data logging of temperature alarms door openings and and RH if required provides a detailed record of environmental conditions to quickly troubleshoot any unexpected results Capability to quickly change both environmental and alarm settings through intuitive controller Diagnostic interface to show system parameters and functions Password protection for secure programmable settings and alarm setpoints e On screen troubleshooting and help OPTIONS see page 10 for details High temperature disinfection e O5 Control choose 1 19 0 1 19 or 1 95 Active humidification Cooling feature 4 or 8 Split sealing inner glass doors Copper chamber and interior e BMS alarm relay contacts Humidity alert package display and alarm WX New Brunswick GALAXY 170 S OPTIONS see page 10 for details The S Series Galaxy incubator provides the same high e High temperature disinfection level of performance as the R Series but uses an 4 or 8 Split sealing inner glass doors easily read LED display for the interface representing an excellent value priced model The 170 S Series is ideal for traditional applications where standard incuba BMS
17. s sensor offers specific measurement and accurate control of CO levels The traditional thermal conductivity TC sensor is highly sensitive to changes in chamber humidity and temperature fluctua tions and is therefore fundamentally unsuitable for use in CO incubators Uniquely the Galaxy IR Sensor can remain in the chamber during the entire high temperature disinfection cycle ensuring that all chamber components are sterilized SIMPLIFIED CLEANING On all models the chambers are pressed from a single sheet of stainless steel with no welds or seams eliminating another potential source of contamination In combination with the easily removable replaceable shelves this makes chamber cleaning a rapid and efficient process so more time can be spent engaged in science and less with maintaining the instrument Available in 14 liter 48 liter amp 170 liter capacities and in choice of sophisticated models with advanced controller or economical S models with LED display Back row Galaxy 170 S left amp 170 R Front row Galaxy 14 S left and 48 R Galaxy 48 S not shown UNIQUE RANGE OF MODEL SIZES In common with our 170 liter incubators our 48 liter and 14 liter incubators incorporate all of the superior design and innovation of the larger units in a smaller format These units offer the ideal environment for hypoxic applications research requiring isolation and IVF research OPTIONS see page 10 fo
18. ubators incorporate the 133mm b 3 intuitive LCD interface and full choice of options allowing for a customizable unit with user friendly control alarm and logging features Ideal applications include cGMP work stem cell research cancer research as well as traditional and non traditional cell culture FEATURES 170 liter 6 0 cu ft capacity on a minimal footprint e IR CO sensor with automatic auto zero programmable function to ensure accurate calibrated measurements e Seamless chamber e 25mm Access port Perforated shelving Sealed inner glass door for atmosphere conservation e RS 232 communications port e Stackable up to two high e Large volume humidification pan with dedicated independent heater e Quick and comprehensive chamber cleaning made effortless e HEPA filtration of gas supply inlets to ensure sterility e 8 position shelving rack with 4 shelves Ji Galaxy 170A um Pe external dimensions allow placement on or under the bench or double stacking on the floor For optimally controlled environments choose full featured Galaxy R or economical S Series incubators CHAMBER TEMP C02 LEVEL 37 0 506 PROGRAMMED TD ALARMS DISARMED UNTIL SETPOINT REACHED TEMP ALARM ARMED COZ WILL ARM AT SETPOINT PROS USER HELE Large back lit displays are standard on all R Series models providing at a glance viewing of multiple parameters helo sc
19. uited for hypoxic applications including in vitro fertilization IVF and stem cell research with control option The relatively compact 48 liter chamber substantially reduces the significant gas consumption often encountered when using larger incubators The controller offers the same 72 hour data logging and diagnostic interface as on the 170 R described on page 4 Examples of graphical logging and alarm screens are shown below laboratories requiring small volume cell culture and are ideal for isolation studies such as viral work Choose full featured R Series or economical S Series models Convenient benchtop size and footprint only 48 x 47 cm 18 9 x 18 5 Integrated heated viewing window in outer door allows observation without disturbing cultures Seamless fanless design RS 232 and 25mm access port Stackable Low gas consumption Perforated shelving to facilitate faster recoveries Large volume humidity pan CO HEPA filtration High temperature disinfection control Choose 1 19 0 1 1996 1 95 Two split inner glass doors Humidity alert package display and alarm BMS management system relays New Bru nsw Ta MIE THT nekt GALAXY 485 Galaxy 48 5 Series incubators are entry level models offering the sa
20. y mimic physiological normoxic conditions and to provide the optimal environment for stem cell work Rapidly emerging stem cell technology requires a greater sophistication in the incubation process than traditional incu bators can provide With the availability of three different ranges of oxygen control 0 1 1996 1 1996 1 95 ranges Galaxy incubators offer stem cell scientists greater choice and flexibility in con trolling cellular levels than any other brand of CO incuba tor The features and design of Galaxy incubators make them ideal for this critical and sensitive emerging field of study IVF APPLICATIONS Galaxy CO incubators allow clinicians and embryologists to closely reliably and repeatability mimic the environmental conditions that sperm oocytes blastocysts and developing embryos encounter in vivo Each Galaxy incubator is custom manufactured giving practitioners the largest choice of optional features Many features can be also be retrofitted at a later date allowing modifications to operating parameters as optimal IVF incubation conditions are further defined Choose from three sizes Galaxy 170 for high cycle throughput clinics and for media storage Galaxy 48 is com pact stackable and easily capable of incubating up to six patient samples Galaxy 14 is ideal for culturing 1 to 2 patient samples and for incubation while samples undergo obser vation and manipulation Wide choice of c
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