neutralex user`s guide
Contents
1. products with their appropriate part number followed by their individual application and procedure Neutralex Bulk Formalin Neutralization 4046 _Neutralex Starter Pack contains all of the following 4047 16 Premeasured Pouches each pouch neutralizes 1 gallon or 4 liters 4050 Aldehyde Test Kit 100 Analytical Test Strips Neutra Wipes Neutralizes Formalin and Vapors Due to Small Spills and Splashes 4278 Starter Pack 1 dispenser and 1 roll of Neutra Wipes 4279 4 Rolls 60 wipes per roll wipe size 12 in x 12 5 in 30 5 cm x 31 8 cm Neutra Pads Grossing Pad that Neutralizes Absorbed Formalin 4295 100 Pads pad size 8 in x 10 in 20 3 cm x 25 4 cm Neutra Form Neutralizes Large Spills 4304 2 Containers each container neutralizes larger spills Revised 06 18 2013 Neutra Guard Aldehyde Control System Tissue Tek Neutralex The ONLY CAL EPA Certified Technology for the Treatment of Formalin Waste Technology Application Complete aldehyde neutralization in 15 minutes drain clogging solids or sludges produced during neutralization and pH is in the normal range Packaged in easy to use foil pouches Each pouch neutralizes one gallon of 10 formalin Technology Procedure 1 The Neutralex Starter Kit consists of a Reaction Container one case of Neutralex an Aldehyde Test Kit a pack of pH strips and a User s Manual 5 1 APPLICATIONS AND ILLU2. Vs Tissue Tek Neutralex SAKUR Aldehyde Neutralizing Agent 2013 Sakura Finetek USA Inc All Rights Reserved Printed in U S A 9 Manufactured for Se d Sakura Finetek USA Inc Torrance CA 90501 U S A Sakura Finetek Japan Co Ltd Tokyo 135 0007 Japan d e Sakura Finetek Europe B V 2408 AV Alphen aan den Rijn NL SAKURA 0003372 01 Rev B TABLE OF CONTENTS Section Page 1 INTRODUCTION ME 1 1 Aldehyde Ee m 1 1 2 PROCEDURES FOR NEUTRALEX Tissue Tek Neutralex NCCLS Formatted Procedure for 10 Formalin VIP Fixative and 2 or 4 Gl t raldeyde et 2 1 Tissue Tek Neutralex Procedure for Neutralizing 37 Formaldeyde se 2 3 Tissue Tek Neutralex Procedure for Neutralizing Alcoholic Formalin ee 2 3 Tissue Tek Neutralex Procedure for Neutralizing Pen Pi AEN 24 Tissue Tek Neutralex Procedure for Neutralizing Surgipath Decalcifier sss 2 5 3 Tissue Tek Neutralex Material Safety Data Sheets Tissue Tek Neutralex Neutra Form Neutra Pads Neutra Wipes Neutralex Adheyde Test Kit 3 1 4 CAL EPA Technology Certification ad sa maakas aaa alamaid 4 1 5 Applications and Illustrated Procedures For All Neutra Guard Products Product Applications Srel 5 1 Neutra Guard Aldehyde Control Sy
3. Period Daily Monthly etc Time YES NO Date Name of Person Inspecting Have all tissue fragments been strained from spent formalin Have any other chemicals been mixed in with the spent formalin Is adequate protective gear such as a lab coat gloves and goggles being used Is neutralization being performed under a hood or in a well ventilated area Is the treatment container free from leaks corrosion and or excessive wear Is the secondary containment secure and free from cracks and accumulated liquids Do liquid levels exceed 8 10 of the container capacity Are all containers properly labeled Is the Aldehyde Waste Treatment Log current Is the Neutralization Inspection Log current NEUTRALIZATION INSPECTION LOG Period Daily Monthly etc Time YES NO 6 2 Have all tissue fragments been strained from spent formalin Have any other chemicals been mixed in with the spent formalin Is adequate protective gear such as a lab coat gloves and goggles being used Is neutralization being performed under a hood or in a well ventilated area Is the treatment container free from leaks corrosion and or excessive wear Is the secondary containment secure and free from cracks and accumulated liquids Do liquid levels exceed 8 10 of the container capacity Are all containers properly labeled Is the Aldehyde Waste Treatment Log curr
4. Product Code 4050 pH Test Strips Reagents Tissue Tek Neutralex Aldehyde Neutralization Agent Sakura Product Code 4047 Procedure 1 Refer to manufacturer s MSDS for the safe handling of 10 formalin Fixative or 2 glutaraldehyde utilizing OSHA mandated protective equipment such as safety goggles gloves and an impervious apron For aldehyde neutralization first separate all of the identifiable tissue specimens from the liquid hazardous waste This shall be performed using an appropriate screen mesh 80 mesh_ is recommended and collecting the aldehydic waste in a calibrated reaction vessel such as the Tissue Reaction Container Sakura Product Code 4276 Volumetric calibration can be in gallon or liter divisions NOTE The neutralization procedure should be performed in an OSHA or AIHA approved ventilated room or under an adequate hood The reaction vessel should be placed in any receptacle providing secondary containment such as a plastic tub closed sink etc A counter top lined with Tissue Neutra Wipes Sakura Product Code 4279 would also suffice as an acceptable means of secondary containment Just prior to neutralization test the aldehyde waste for pH and record the results in a Hazardous Waste Log refer to step 10 Be sure that the aldehyde solution being neutralized does not have a pH of 4 or less 2 1 PROCEDURES FOR NEUTRALEX 5 Determine the total volume of
5. of Decalcifier waste to the calibrated reaction container 4 Add 1 1 3 gallons of 10 sodium hydroxide to the reaction container Mix solution for 15 seconds and let stand 1 minute 5 Add one pouch of Tissue Tek Neutralex to the reaction container Pour the complete contents of the pouch into the calibrated reaction vessel and mix for 15 seconds 6 Cap the vessel and let it stand for 15 minutes 7 Test the neutralized Decalcifier waste solution for residual aldehyde as outlined below Revised 06 18 2013 Residual Aldehyde Test Procedure a Rinse the test vessel with the sample solution and fill to the 5mL mark b Immerse the reaction zone of the Aldehyde test Strip into the solution for 20 seconds c Shake off excess liquid from the strip then compare the reaction zone with color scale 2 5 PROCEDURES FOR NEUTRALEX Revised 06 18 2013 Section 3 MATERIAL SAFETY DATA SHEETS Tissue Tek Neutralex Material Safety Sheets Tissue Tek Neutralex RE 4047 TissueTek Neutra Form REI 4304 Tissue Neutra Pads RE 4295 Neutra Wipes RE 4728 amp RE 4729 Neutralex Aldehyde Test Kit Revised 06 18 2013 3 1 7 MATERIAL SAFETY DATA SHEET SAKURA In accordance with ISO 11014 2009 Standard MSDS 0002144 02 Rev D Original Preparation Date 12 01 08 Revision Date 09 17 12 1 Chemical Product and Company Identification Product Name Tis
6. side up on any cutting surface The tissue is placed on the pad where it is then dissected and examined The formalin is simultaneously absorbed and neutralized resulting in lower vapor concentrations and easy disposal 4295 100 8 x 10 Pads per case Revised 06 18 2013 Tissue Tek Neutra Form Product Application To be used as a fast effective neutralizing agent for accidental aldehyde spills in large quantities When used in accordance with the recommended procedure it eliminates harmful vapors and neutralizes hazardous aldehydes Voted the number one spill control agent by an independent source Product Procedure 1 Neutra Form is packaged in easy to pour dispensing containers There are two containers per case Revised 06 18 2013 Dispense the Neutra Form from the plastic bottle and surround the spill Once contained sprinkle more of the product over the body of the spill Wait 15 minutes for completion of aldehyde neutralization Unlike other products the final pH is in a safe neutral range 4304 2x85 oz Container Pack 5 5 APPLICATIONS AND ILLUSTRATIONS 5 6 Revised 06 18 2013 Section 6 ALDEHYDE WASTE TREATMENT LOG Institution Person Performing Quantity Being pH of Neutralized Date of Treatment Residual PPM Procedure Neutralized Solution Revised 06 18 2013 6 1 ALDEHYDE WASTE TREATMENT LOG Date Name of Person Inspecting NEUTRALIZATION INSPECTION LOG
7. the quantity that comes in contact with an eye the injuries sustained may range from mild irritation to redness and burning Respiratory or Skin Sensitization N A Reproductive Cell Mutagenicity N A Carcinogenicity N A Reproductive Toxicity N A Specific Target Organ Toxicity single exposure Ingestion Single dose oral toxicity is slight Symptoms may include stomach irritation nausea and diarrhea Specific Target Organ Toxicity repeated exposure N A Aspiration Inhalation Hazard No reported effects 12 Ecological Information Aquatic Bioassay was conducted using guidelines prescribed in Static Acute Bioassay Procedure for Hazardous Waste for Samples result status pass 96 hour LCsq gt 750 mg l Ecotoxicity N A Persistence and Degradability N A Bioaccumulative Potential N A Mobility in Soil N A 13 Disposal Considerations Disposal Method Dispose of in accordance with all applicable local state and federal regulations 14 Transport Information UN Number N A UN Proper Shipping Name N A UN Classification N A Marine Pollutant Y N N A OTHER SHIPPING INFORMATION N A Markings N A Hazardous Substance RQ N A SPECIAL SHIPPING NOTES N A IMDG N A IATA N A DOT Shipping Number None Assigned DOT Hazard Classification None Assigned 15 Regulatory Information UNITED STATES SARA Title III Superfund Amendments and Reauthorization Act SARA Title III Sect 302 Extremely Hazar
8. waste US EPA guidelines for the classification determination are listed in 40 CFR Parts 261 3 Additionally waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification RCRA P Series None listed RCRA U Series None listed 14 Transport Information UN Number N A UN Proper Shipping Name N A UN Classification N A Marine Pollutant Y N N A OTHER SHIPPING INFORMATION N A Markings N A Hazardous Substance RQ N A SPECIAL SHIPPING NOTES N A IMDG N A IATA N A US DOT No information available CANADA TDG No information available 15 Regulatory Information US FEDERAL TSCA Not listed on the TSCA inventory Health Safety Reporting List None of the chemicals are on the Health amp Safety Reporting List Chemical Test Rules None of the chemicals in this product are under a Chemical Test Rule Section 12b None of the chemicals are listed under TSCA Section 12b TSCA Significant New Use Rule None of the chemicals in this material have a SNUR under TSCA SARA CERCLA Hazardous Substances and corresponding RQs None of the chemicals in this material have an RQ SARA Section 302 Extremely Hazardous Substances None of the chemicals in this product have a TPQ Section 313 No chemicals are reportable under Section 313 Clean Air Act This material does not contain any hazardous air pollutants This material does not contain any Class 1 Ozone
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10. STRATIONS 2 Gallon increments of spent formalin or glutaraldehyde 5 After 15 minutes extract 5 mL of the solution and are added to the Reaction Container transfer it to the plastic cuvette supplied in the Aldehyde Test Kit E yap an 3 Add one pouch of Neutralex for each gallon of to be neutralized 6 Test for pH first by dipping a pH determination strip into the neutralized solution and reading it 2 1 NB 7 Immerse the aldehyde test strip into the solution for 4 Swirl the mixture for approximately 10 to 15 seconds 20 seconds and read it then let it stand for 15 minutes Neutralex goes into solution easily and will not clump even after prolonged standing 5 2 Revised 06 18 2013 8 Record all results in the Hazardous Waste Log that is Tissue Tek Neutra Wipes supplied in the User s Manual Product Application Neutra Wipes function as a primary means of absorbing and neutralizing formalin spills They will eradicate vapors in formalin storage areas when used as a shelf liner Excellent for use in hospital operating rooms and transporting carts Very effective in courier vehicles to control the noxious vapors of spilled or leaving containers Product Procedure 1 Neutra Wipes can be purchased in a starter pack that includes one dispenser and a roll of wipes Refill rolls are available 4046 Neutralex Starter Pack
11. Tissue Tek Neutralex required for the detoxification of the aldehyde waste by using the following procedure Determine the total volume of 10 formalin or 2 glutaraldehyde waste present Use one pouch of Tissue Tek Neutralex for each gallon of 10 formalin or two gallons of 2 glutaraldehyde waste Pour the complete contents of each pouch into the calibrated reaction vessel containing the waste Shake stir or swirl the mixture for five to ten seconds 6 Cap the vessel and let it stand for 15 minutes Swirl once again prior to testing 7 Using a pipette extract 5 ml of treated waste from the vessel and transfer it to the plastic cuvette that is supplied in the Tissue Tek Aldehyde Test Kit Sakura Product Code 4050 There is a 5 ml line already printed on the cuvette Test the pH by using ordinary laboratory pH strips Record the results in a Hazardous Waste Log refer to step 10 After completing this save the contents of the cuvette and test for residual aldehyde using the Tissue Aldehyde Test Kit The procedure is discussed in step 8 8 Using the same cuvette from step 7 that is still filled with the treated waste perform the residual aldehyde test as follows a Remove an Aldehyde test strip from the vial provided in the kit b Immerse the reaction zone of the test strip into the solution for 20 seconds c Shake off the excess liquid from the strip then compare the reaction zone color of the s
12. UN Classification N A Marine Pollutant Y N N A OTHER SHIPPING INFORMATION N A Markings N A Hazardous Substance RQ N A SPECIAL SHIPPING NOTES N A IMDG N A IATA N A DOT Shipping Number None Assigned DOT Hazard Classification None Assigned 15 Regulatory Information UNITED STATES SARA Title III Superfund Amendments and Reauthorization Act SARA Title III Sect 302 Extremely Hazardous Substances 40 CFR 355 Not listed SARA Title III Sect 313 Reportable Ingredients 40 CFR 372 65 Not listed CERCLA Comprehensive Environmental Response Compensation and Liability Act Not listed RCRA Hazardous Waste 40 CFR 261 33 Not listed STATE REGULATIONS Proposition 65 Not listed 16 Other Information This Material Safety Data Sheet has been furnished on request A revised Material Safety Data Sheet will be furnished only if requested also in case of specification changes The above information which is accurate to the best of our knowledge and belief describes the safety aspects of our product but does not warrant any product properties The company gives no warranty as to the accuracy or completeness of such information als 7 MATERIAL SAFETY DATA SHEET SAKURA In accordance with ISO 11014 2009 Standard MSDS 0003382 02 Rev D Original Preparation Date 12 01 2008 Revision Date 03 27 2012 1 Chemical Product and Company Identification Product Name Tissue Tek Neutralex Aldehyde Test Kit produ
13. al into clean dry container and cover remove from area Flush spill area with water 7 Handling and Storage Handling N A Storage Suitable for any general chemical storage area All electrical eguipment in storage and or handling areas should be installed in accordance with applicable requirements of the National Electrical Code NEC 8 Exposure Controls and Personal Protection Permissible concentration N A Engineering Controls N A PERSONAL PROTECTIVE EQUIPMENT Respiratory Protection General mechanical or local exhaust should be used to maintain low exposure levels Avoid prolonged periods of directly breathing vapors In absence of proper environmental controls the use of a NIOSH OSHA respirator is recommended Respirator use should comply with OSHA 29 CFR 1910 134 Hand Protection Use appropriate resistant gloves Eye Protection Chemical splash goggles Skin and Body Protection Normal laboratory work clothing covering arms and legs Protective Clothing Normal laboratory work clothing covering arms and legs 9 Physical and Chemical Properties Appearance White Powder Odor N A pH 6 5 7 0 Melting Point N A Freezing Point N A Boiling Point N A Flash Point N A Vapor Pressure N A Vapor Density N A Density Relative Density N A Solubility N A n Octano Water Partition Coefficient N A Auto Ignition Temperature N A Decomposition Temperature N A Odor Threshold N A Evaporation Rate N A Flamma
14. ation nausea and diarrhea 12 Ecological Information Ecotoxicity Aquatic Bioassay was conducted using guidelines prescribed in Static Acute Bioassay Procedure for Hazardous Waste for Samples result status pass 96 hour LC50 gt 750 mg l This product is within the allowable limits specified in 40 CFR 261 and 433 11 California Soluble Threshold Limit Concentrations STLCs and Total Threshold Limit Concentration TTLCs and is considered a non hazardous material Persistence and Degradability N A Bioaccumulative Potential N A Mobility in Soil N A 13 Disposal Considerations Disposal Method Dispose of in accordance with all applicable local state and federal regulations 14 Transport Information UN Number N A UN Proper Shipping Name N A UN Classification N A Marine Pollutant Y N N A OTHER SHIPPING INFORMATION N A Markings N A Hazardous Substance RQ N A SPECIAL SHIPPING NOTES N A IMDG N A IATA N A DOT Shipping Number None Regulated DOT Hazard Classification None Regulated 15 Regulatory Information UNITED STATES SARA Title III Superfund Amendments and Reauthorization Act SARA Title III Sect 302 Extremely Hazardous Substances 40 CFR 355 Not listed SARA Title III Sect 313 Reportable Ingredients 40 CFR 372 65 Not listed CERCLA Comprehensive Environmental Response Compensation and Liability Act Not listed RCRA Hazardous Waste 40 CFR 261 33 Not listed STATE REGULATIONS P
15. bility N A Viscosity N A Percent Volatile by Volume N A Specific Gravity Greater than water 10 Stability and Reactivity Conditions to Avoid N A Incompatible Materials Avoid contact with strong oxidizing agents and acids Mixing with acids it can generate sulfur dioxide Stability Stable Hazardous Decomposition Products N A Hazardous Polymerization Cannot occur 11 Toxicological Information Acute Toxicity N A Skin Irritation Corrosion Burning Exposure causes skin irritation redness and burning Pre existing skin conditions could be aggravated Absorption through skin is unlikely Eye Damage Irritation Depending on the quantity that comes in contact with an eye the injuries sustained may range from mild irritation to redness and burning Respiratory or Skin Sensitization N A Reproductive Cell Mutagenicity N A Carcinogenicity The ingredients in this product are not carcinogenic None of the ingredients of this product are listed in California s Proposition 65 or IRAC list of carcinogens Reproductive Toxicity N A Specific Target Organ Toxicity single exposure N A Specific Target Organ Toxicity repeated exposure N A Aspiration Inhalation Hazard Dust can cause irritation of nasal and respiratory passages Wear a NIOSH approved respirator when working with chemicals unless work is conducted in a ventilated hood Ingestion Single dose oral toxicity is moderate Symptoms may include stomach irrit
16. bility and Reactivity Conditions to Avoid None reported Incompatible Materials N A Stability Stable Hazardous Decomposition Products No data available Hazardous Polymerization Will not occur 11 Toxicological Information RTECSt CAS NA LD50 LC50 CAS N A Acute Toxicity No information found Skin Irritation Corrosion Burning No information found Eye Damage lrritation No information found Respiratory or Skin Sensitization No information found Reproductive Cell Mutagenicity No information found Carcinogenicity Not listed by ACGIH IARC NTP or CA Prop 65 Reproductive Toxicity No information found Specific Target Organ Toxicity single exposure No information found Specific Target Organ Toxicity repeated exposure No information found Aspiration Inhalation Hazard No information found Epidemiology No Data Teratogenicity No information found Neurotoxicity No information found Mutagenicity No information found Other Studies See actual entry in RTECS for complete information 12 Ecological Information Ecotoxicity No data available No information available Persistence and Degradability N A Bioaccumulative Potential N A Mobility in Soil N A Environmental Expected to evaporate Physical No information available Other No information available 13 Advice on Disposal Chemical waste generators must determine whether a discarded chemical is classified as a hazardous
17. brought to fresh air If necessary administer CPR keep warm and quiet Seek immediate medical attention Skin Contact Contaminated clothing should be removed immediately The affected body areas should be flushed with water for a period of approximately 15 minutes If symptoms persist seek medical attention Eye Contact Do not allow victim to rub or keep eyes tightly shut Flush eyes immediately with water for 10 15 minutes If burning persists seek medical care Ingestion Give plenty of water or milk to drink If conscious induce vomiting by touching finger to back of throat Get immediate medical attention Never give anything by mouth to an unconscious person 5 Fire Fighting Measures Extinguishing Media Water fog regular foam dry chemicals or carbon dioxide Fire Explosion Hazards N A Fire Fighting Procedures Wear self contained breathing apparatus with full body protection Sensitivity to Static Discharge N A Hazardous Decomposition Products Sulfur oxides can be generated upon adding or mixing with acids Store the product away from acids and oxidizers Flash Point and Method Noncombustible Flammable Limits N A Auto Ignition Temperature N A 6 Accidental Release Measures Personal Precautions N A Protective Eguipment N A Emergency Procedures N A Environmental Precautions N A Methods and Materials for Containment N A Methods and Materials for Cleaning Up With clean dry shovel carefully place materi
18. ct code 4050 Synonyms ATK Recommended Uses Aldehyde Neutralization Manufactured For Sakura Finetek USA Inc Emergency Telephone Number Torrance CA 90501 USA 800 424 9300 Chemtrec Tel 310 972 7800 2 Hazards Identification EMERGENCY OVERVIEW DANGER Appearance Polyethylene paper stick Non hazardous Target Organs None Health Effects Potential Health Effects Eye Non irritating to the eyes Skin Non irritating to skin Ingestion No Hazard expected in normal industrial use Inhalation No Hazard expected in normal industrial use Chronic None 3 Composition Information on Ingredients Non Hazardous 4 First Aid Measures Inhalation Get medical aid if cough or other symptoms appear Skin Contact Get medical aid if irritation develops or persists Eye Contact If irritation develops get medical aid Ingestion Get medical aid if irritation or symptoms occurs Notes to Physician Treat symptomatically and supportively 5 Fire Fighting Measures General Information Material may burn Extinguishing Media Use agent most appropriate to extinguish surrounding fire Fire Explosion Hazards N A Fire Fighting Procedures N A Sensitivity to Static Discharge N A Hazardous Decomposition Products N A Flash Point and Method N A Flammable Limits N A Auto Ignition Temperature N A NFPA Rating estimated Health 0 Flammability 0 Instability 0 6 Accidental Release Measures Personal Precauti
19. d Third two packets of Neutralex are required to neutralize one gallon of the Pen Fix The changes are implemented in the following procedure Operating Procedure Instructions for the Neutralization of Pen Fix 1 Refer to the manufacturers MSDS for the safe handling of 10 alcoholic formalin and OSHA mandated protective equipment e g safety goggles gloves impervious apron etc 2 For Pen Fix treatment all identifiable tissue must be separated from the liquid hazardous waste This shall be performed using the proper screen e g 80 mesh The liquid aldehydic waste is then collected in a calibrated reaction vessel Volumetric calibration can be in gallon or liter divisions preferably gallons 3 Calculate the volume of Tissue Tek Neutralex required to neutralize the Pen Fix waste by using the following procedure determine the total volume in whole gallons of Pen Fix to be neutralized Use TWO pouches of Tissue Tek Neutralex per gallon of Pen Fix waste Pour the complete contents of each pouch into the calibrated reaction vessel 4 Add an equal amount of water to the reaction vessel For example if one gallon of Pen Fix is to be treated add one gallon of water Two gallons of waste two gallons of water Shake or stir the mixture for fifteen or twenty seconds until the Neutralex is dissolved 5 Cap the vessel and let it stand for 90 minutes 6 Test the neutralized Pen Fix waste solution for residual aldeh
20. de concentrations can be verified by using the Tissue Tek Aldehyde Test Kit described in steps 7 and 8 of the procedure section References Luna Lee G Histopathological Methods and Color Atlas of Special Stains and Tissue Artifacts American Histolabs Inc Publishing Division 1992 California Environmental Agency Department of Toxic Substances Control Hazardous Waste Performance Certificate July 1995 NOTE For additional work practice controls in neutralizing formalin spills and eliminating harmful vapors while performing grossing procedures please refer to Section 5 of this manual for more information on Neutra Pads Neutra Wipes and Neutra Form Revised 06 18 2013 Neutralex Procedure for Neutralizing 37 Formaldehyde Operating Procedure Instructions for the neutralization of 37 Formaldehyde 1 Refer to the manufacturers MSDS for the safe handling of glutaraldehyde and OSHA mandated protective equipment e g safety goggles gloves impervious apron etc 2 For aldehyde neutralization all identifiable tissue must be separated from the liquid hazardous waste This shall be performed using the proper screen e g 80 mesh The liquid aldehydic waste is then collected in a calibrated reaction vessel Volumetric calibration can be in gallon or liter divisions preferably gallons 3 Reduce the concentration of the 37 formaldehyde by diluting it as follows 1 part formaldehyde t
21. de secret Trade secret 5 mg m3 5 mg m3 4 First Aid Measures Inhalation The patient should be transported away from exposure and brought to fresh air If necessary administer CPR keep warm and quiet Seek immediate medical attention Skin Contact Contaminated clothing should be removed The affected body areas should be flushed with water for a period of approximately 15 minutes If symptoms persist seek medical attention Eye Contact Flush eyes immediately with water for 10 15 minutes If burning persists seek medical care Ingestion Do not induce vomiting Drink water or milk Continue ingesting fluids until medical help is obtained Unconscious victims should be placed on their left side with their head down Do not induce vomiting 5 Fire Fighting Measures Extinguishing Media Water fog regular foam dry chemicals or carbon dioxide Fire Explosion Hazards N A Fire Fighting Procedures Wear self contained breathing apparatus with full body protection Sensitivity to Static Discharge N A Hazardous Decomposition Products None Flash Point and Method N A Flammable Limits N A Auto Ignition Temperature N A 6 Accidental Release Measures Personal Precautions N A Protective Eguipment N A Emergency Procedures N A Environmental Precautions N A Methods and Materials for Containment N A Methods and Materials for Cleaning Up N A 7 Handling and Storage Handling All electrical eguipment in stora
22. depletors This material does not contain any Class 2 Ozone depletors Clean Water Act None of the chemicals in this product are listed as Hazardous Substances under the CWA None of the chemicals in this product are listed as Priority Pollutants under the CWA None ofthe chemicals in this product are listed as Toxic Pollutants under the CWA OSHA None of the chemicals in this product are considered highly hazardous by OSHA STATE Not present on state lists from CA PA MN MA FL or NJ California No Significant Risk Level None of the chemicals in this product are listed European International Regulations European Labeling in Accordance with EC Directives Hazard Symbols Not available Risk Phrases N A Safety Phrases S 24 25 Avoid contact with skin and eyes WGK Water Danger Protection No information available Canada DSL NDSL Not listed on Canada s DSL List Canada WHMIS WHMIS Not available Canadian Ingredient Disclosure List 16 Other Information This Material Safety Data Sheet has been furnished on request A revised Material Safety Data Sheet will be furnished only if requested also in case of specification changes The above information which is accurate to the best of our knowledge and belief describes the safety aspects of our product but does not warrant any product properties The company gives no warranty as to the accuracy or completeness of such information Section 4 CAL EPA TECHNOLO
23. dous Substances 40 CFR 355 Not listed SARA Title III Sect 313 Reportable Ingredients 40 CFR 372 65 Not listed CERCLA Comprehensive Environmental Response Compensation and Liability Act Not listed RCRA Hazardous Waste 40 CFR 261 33 Not listed STATE REGULATIONS Proposition 65 Not listed 16 Other Information This Material Safety Data Sheet has been furnished on request A revised Material Safety Data Sheet will be furnished only if requested also in case of specification changes The above information which is accurate to the best of our knowledge and belief describes the safety aspects of our product but does not warrant any product properties The company gives no warranty as to the accuracy or completeness of such information als 7 MATERIAL SAFETY DATA SHEET SAKURA In accordance with ISO 11014 2009 Standard MSDS 0003385 01 Rev D Original Preparation Date 12 01 08 Revision Date 09 17 12 1 Chemical Product and Company Identification Product Name Tissue Tek NEUTRA WIPES product codes 4278 and 4279 Synonym s N A Recommended Uses N A Manufactured For Sakura Finetek USA Inc Emergency Telephone Number Torrance CA 90501 USA 800 424 9300 Chemtrec Tel 310 972 7800 2 Hazards Identification EMERGENCY OVERVIEW DANGER N A Health Effects N A Primary Entry Routes Inhalation and eye contact Target organs Respiratory tract eyes Carcinogenicity IARC NTP and OSHA do not list chem
24. e product in this system and as you will learn in Section 5 the combined use of all Neutra Guard products present viable solutions for the safe management of aldehyde disposal and vapor control Revised 06 18 2013 Section 1 INTRODUCTION Revised 06 18 2013 Section 2 PROCEDURES FOR NEUTRALEX Tissue Tek Neutralex NCCLS Formatted Procedure for 10 Formalin VIP Fixative and 2 or 4 Glutaraldehyde NAME DATE Adopted Reviewed Reviewed Reviewed Reviewed Reviewed Principle The Tissue Tek Neutralex aldehyde neutralization technology was designed to treat aldehydic wastewater in a batch processing mode The spent aldehydic solutions are transferred to a collection vessel and treated with a pre measured amount of Tissue Tek Neutralex to render a non hazardous liquid waste After being tested with the Tissue Tek Aldehyde Test Kit the solution may then be disposed of as a non hazardous waste and discharged to the sanitary sewer Analytical data on the reaction by products indicates that this non hazardous waste has the following characteristics water white color no residual aldehydic odor no solid polymer waste and no turbidity problems Revised 06 18 2013 Solutions to be Neutralized 10 formalin VIP Fixative or 2 glutaraldehyde Equipment Tissue Tek Reaction Container 2 5 gallon Sakura Product Code 4276 Tissue Tek Aldehyde Test Kit Sakura
25. efficient N A Auto Ignition Temperature N A Decomposition Temperature N A Odor Threshold N A Evaporation Rate N A Flammability N A Viscosity N A Specific Gravity Greater than water Percent Volatile by Volume N A 10 Stability and Reactivity Conditions to Avoid Strong oxidixing agents Incompatible Materials Avoid contact with strong mineral acids and strong oxidixing agents Stability Stable Hazardous Decomposition Products N A Hazardous Polymerization Cannot occur 11 Toxicological Information Acute Toxicity N A Skin Irritation Corrosion Burning Exposure causes skin irritation redness and burning Pre existing skin conditions could be aggravated Absorption through skin is unlikely Eye Damage Irritation Depending on the quantity that comes in contact with an eye the injuries sustained may range from mild irritation to redness and burning Respiratory or Skin Sensitization N A Reproductive Cell Mutagenicity N A Carcinogenicity IARC NTP and OSHA do not list chemical ingredients as a carcinogen Reproductive Toxicity N A Specific Target Organ Toxicity single exposure Ingestion Single dose oral toxicity is moderate Symptoms may include stomach irritation nausea and diarrhea Specific Target Organ Toxicity repeated exposure N A Aspiration Inhalation Hazard Dust can cause irritation of nasal and respiratory passages 12 Ecological Information Aquatic Bioassay was conducted using
26. ek Neutralex required to neutralize the aldehyde waste by using the following procedure Determine the total volume in whole gallons or liters of 10 alcoholic formalin to be neutralized Use one pouch of Neutralex per gallon or liter of aldehydic waste Pour the complete contents of each pouch into the calibrated reaction vessel 4 Add an equal amount of water to the reaction vessel For example if one gallon of alcoholic formalin is to be treated add one gallon of water Two gallons of waste two gallons of water Shake or stir the mixture for fifteen seconds 5 Capthe vessel and let it stand for 90 minutes 6 Test the neutralized waste solution for residual aldehyde Residual Aldehyde Test Procedure a Rinse the test vessel with the sample solution and fill to the 5mL mark b Immerse the reaction zone of the Aldehyde test strip into the solution for 20 seconds c Shake off excess liquid from the strip then compare the reaction zone with color scale 2 3 PROCEDURES FOR NEUTRALEX Tissue Tek Neutralex Procedure for Neutralizing Pen Fix The following is the procedure for neutralizing Pen Fix with Tissue Tek NeutraleX There are three basic changes that represent a deviation from the normal procedure for neutralizing Pen Fix Fixative First the reaction time will be increased from 15 to 90 minutes Second an equal amount of water will be added to the volume of Pen Fix to be neutralize
27. ent Is the Neutralization Inspection Log current Revised 06 18 2013
28. ge and or handling areas should be installed in accordance with applicable requirements of the National Electrical Code NEC Storage Suitable for any general storage area 8 Exposure Controls and Personal Protection Permissible concentration N A Engineering Controls N A PERSONAL PROTECTIVE EQUIPMENT Respiratory Protection General office or laboratory ventilation Hand Protection Use of gloves is suggested Eye Protection N A Skin and Body Protection N A Protective Clothing N A 9 Physical and Chemical Properties Appearance Blue White Cloth Odor N A pH N A Melting Point N A Freezing Point N A Boiling Point N A Flash Point N A Vapor Pressure N A Vapor Density N A Density Relative Density N A Solubility N A n Octano Water Partition Coefficient N A Auto Ignition Temperature N A Decomposition Temperature N A Odor Threshold N A Evaporation Rate N A Flammability N A Viscosity N A Specific Gravity N A Percent Volatile by Volume N A 10 Stability and Reactivity Conditions to Avoid N A Incompatible Materials Strong oxidizers Stability Stable Hazardous Decomposition Products N A Hazardous Polymerization Cannot occur 11 Toxicological Information Acute Toxicity N A Skin Irritation Corrosion Burning Excessive exposure may cause mild skin irritation Pre existing skin conditions could be aggravated Absorption through skin is unlikely Eye Damage Irritation Depending on
29. guidelines prescribed in Static Acute Bioassay Procedure for Hazardous Waste for Samples result status pass 96 hour LCsp gt 750 mg l NEUTRA FORM is within the allowable limits specified in 40 CFR 261 and 433 11 California Soluble Threshold Limit Concentrations STLCs and Total Threshold Limit Concentration TTLCs and 1s considered a non hazardous material Ecotoxicity N A Persistence and Degradability N A Bioaccumulative Potential N A Mobility in Soil N A 13 Disposal Considerations Disposal Method Dispose of in accordance with all applicable local state and federal regulations 14 Transport Information UN Number N A UN Proper Shipping Name N A UN Classification N A Marine Pollutant Y N N A OTHER SHIPPING INFORMATION N A Markings N A Hazardous Substance RQ N A SPECIAL SHIPPING NOTES N A IMDG N A IATA N A DOT Shipping Number None Assigned DOT Hazard Classification None Assigned 15 Regulatory Information UNITED STATES SARA Title III Superfund Amendments and Reauthorization Act SARA Title III Sect 302 Extremely Hazardous Substances 40 CFR 355 Not listed SARA Title III Sect 313 Reportable Ingredients 40 CFR 372 65 Not listed CERCLA Comprehensive Environmental Response Compensation and Liability Act Not listed RCRA Hazardous Waste 40 CFR 261 33 Not listed STATE REGULATIONS Proposition 65 Not listed 16 Other Information This Material Safety Data Sheet has been f
30. ical ingredients as a carcinogen HMIS Rating HMIS Rating Scale Health 1 Minimal 0 Flammability 0 Slight 1 Reactivity 0 Moderate 2 Protection N A High 3 Severe 4 HMIS Rating Notes Protection N A 3 Composition Information on Ingredients Hazardous Component Specific CAS WEIGHT NIOSH or ACGIH TLV Chemical Identity OSHA Trade secret chemical identity withheld Trade secret Trade secret 5 mg m3 5 mg m3 4 First Aid Measures Inhalation The patient should be transported away from exposure and brought to fresh air If necessary administer CPR keep warm and quiet Seek immediate medical attention Skin Contact Contaminated clothing should be removed The affected body areas should be flushed with water for a period of approximately 15 minutes If symptoms persist seek medical attention Eye Contact Flush eyes immediately with water for 10 15 minutes If burning persists seek medical care Ingestion Do not induce vomiting Drink water or milk Continue ingesting fluids until medical help is obtained Unconscious victims should be placed on their left side with their head down Do not induce vomiting 5 Fire Fighting Measures Extinguishing Media Water fog regular foam dry chemicals or carbon dioxide Fire Explosion Hazards N A Fire Fighting Procedures Wear self contained breathing apparatus with full body protection Sensitivity to Static Discharge N A Hazardous Decomposition Pr
31. includes all of the above 4047 16 Pre Measured Pouches each pouch neutralizes one gallon 4276 2 5 Gallon Reaction Container 2 Tear off as many sheets from the dispenser as is 4050 necessary to completely absorb the spill The Aldehyde Test Kit 100 Analytical Test Strips formalin is neutralized and the vapors are eliminated Revised 06 18 2013 5 3 APPLICATIONS AND ILLUSTRATIONS 3 When using the Wipes as a shelf liner they absorb and neutralize formalin leakage from containers and help eliminate noxious vapors T BR ZE MIL We lig Le 4 Neutra Wipes are very effective in operating rooms and on surgical carts when tissues are being transported A Wipe wrapped around containers holding tissue specimens will absorb and neutralize any splash or spill 4279 60 12 x 12 5 Wipes per Roll 4 Rolls per Case 4278 Starter Pack One Dispenser and one Roll of Neutra Wipes 5 4 Tissue Tek Neutra Pads Product Application Neutra Pads were designed as a working surface blue side up during grossing procedures They are the only pad product that actually neutralizes formalin up to 80 ML Plastic backing on Pad prevents escape of formalin and keeps work area drier cleaner and safer Product Procedure 1 Neutra Pads were designed to absorb and neutralize formalin during grossing procedures Packaged in resealable bags 10 per bag and 100 per case Place the pad with the blue
32. ironmental Precautions N A Methods and Materials for Containment N A Methods and Materials for Cleaning Up With clean dry shovel carefully place material into clean dry container and cover remove from area Flush spill area with water 7 Handling and Storage Handling All electrical eguipment in storage and or handling areas should be installed in accordance with applicable requirements of the National Electrical Code NEC Storage Suitable for any general chemical storage area 8 Exposure Controls and Personal Protection Permissible concentration N A Engineering Controls N A PERSONAL PROTECTIVE EQUIPMENT Respiratory Protection General mechanical or local exhaust should be used to maintain low exposure levels Avoid prolonged periods of directly breathing vapors In absence of proper environmental controls the use of a NIOSH OSHA respirator is recommended Respirator use should comply with OSHA 29 CFR 1910 134 Hand Protection Use appropriate resistant gloves Eye Protection Use chemical splash goggles Skin and Body Protection N A Protective Clothing Use normal laboratory work clothing covering arms and legs 9 Physical and Chemical Properties Appearance Whitish powder Odor N A pH After Neutralization gt 6 Melting Point N A Freezing Point N A Boiling Point N A Flash Point N A Vapor Pressure N A Vapor Density N A Density Relative Density N A Solubility N A n Octano Water Partition Co
33. o 9 parts water The concentration of formaldehyde should now be in the 10 range which is the normal concentration for any working formalin solution The remainder of the neutralization procedure is identical to the procedure outlined in the NCCLS format for 10 formalin Tissue Tek Neutralex Procedure for Neutralizing Alcoholic Formalin The following is the procedure for neutralizing 1096 alcoholic formalin with Tissue Tek Neutralex There are three basic changes that represent a deviation from the normal procedure for neutralizing just 1096 neutral buffered formalin First the reaction time will be increased from 15 to 90 minutes Second an equal amount of water will be added to the volume of alcoholic formalin to be neutralized The last change takes place in the Aldehyde Test Kit procedure Revised 06 18 2013 Operating Procedure Instructions for the Neutralization of Alcoholic Formalin Refer to the manufacturers MSDS for the safe handling of 10 alcoholic formalin and OSHA mandated protective equipment e g safety goggles gloves impervious apron etc 2 For aldehyde neutralization all identifiable tissue must be separated from the liquid hazardous waste This shall be performed using the proper screen e g 80 mesh The liquid aldehydic waste is then collected in a calibrated reaction vessel Volumetric calibration can be in gallon or liter divisions preferably gallons 3 Calculate the volume of Tissue T
34. oducts None Flash Point and Method N A Flammable Limits N A Auto Ignition Temperature N A 6 Accidental Release Measures Personal Precautions N A Protective Eguipment N A Emergency Procedures N A Environmental Precautions N A Methods and Materials for Containment N A Methods and Materials for Cleaning Up N A 7 Handling and Storage Handling electrical equipment in storage and or handling areas should be installed in accordance with applicable requirements of the National Electrical Code NEC Storage Suitable for any general chemical storage area 8 Exposure Controls and Personal Protection Permissible concentration N A Engineering Controls N A PERSONAL PROTECTIVE EQUIPMENT Respiratory Protection General office or laboratory ventilation Hand Protection Use of gloves is suggested Eye Protection N A Skin and Body Protection N A Protective Clothing N A 9 Physical and Chemical Properties Appearance White Cloth Odor N A pH N A Melting Point N A Freezing Point N A Boiling Point N A Flash Point N A Vapor Pressure N A Vapor Density N A Density Relative Density N A Solubility N A n Octano Water Partition Coefficient N A Auto Ignition Temperature N A Decomposition Temperature N A Odor Threshold N A Evaporation Rate N A Flammability N A Viscosity N A Specific Gravity N A Percent Volatile by Volume N A 10 Stability and Reactivity Conditions to A
35. ons Use proper Personal protective equipment as indicated in Section 8 Protective Eguipment Use proper Personal protective eguipment as indicated in Section 8 Emergency Procedures N A Environmental Precautions N A Methods and Materials for Containment N A Methods and Materials for Cleaning Up N A 7 Handling and Storage Handling No special handling procedures are reguired Storage Store in a cool dry location 8 Exposure Controls and Personal Protection Permissible Concentration No OSHA Vacated PELs are listed for this chemical Engineering Controls There are no special ventilation reguirements PERSONAL PROTECTIVE EOUIPMENT Respiratory Protection Respirator protection is not normally reguired Hand Protection Glove protection is not normally reguired Eye Protection Eye protection is not normally reguired Skin and Body Protection N A Protective Clothing Protective garments are not normally reguired 9 Physical and Chemical Properties Appearance Solid Plastic Cellulose Odor No odor pH N A Melting Point N A Freezing Point N A Boiling Point N A Flash Point N A Vapor Pressure N A Vapor Density N A Density Relative Density N A Solubility Not available n Octano Water Partition Coefficient N A Auto Ignition Temperature N A Decomposition Temperature Not available Odor Threshold N A Evaporation Rate gt 1 Butyl acetate 1 Flammability N A Viscosity Not available 10 Sta
36. roposition 65 This product does not contain any PROP 65 compounds that are known to cause cancer or birth defects 16 Other Information This Material Safety Data Sheet has been furnished on request A revised Material Safety Data Sheet will be furnished only if requested also in case of specification changes The above information which is accurate to the best of our knowledge and belief describes the safety aspects of our product but does not warrant any product properties The company gives no warranty as to the accuracy or completeness of such information als 7 MATERIAL SAFETY DATA SHEET SAKURA In accordance with ISO 11014 2009 Standard MSDS 0003383 01 Rev D Original Preparation Date 12 01 08 Revision Date 09 17 12 1 Chemical Product and Company Identification Product Name Tissue Tek NEUTRA FORM product code 4304 Synonym s N A Recommended Uses N A Manufactured For Sakura Finetek USA Inc Emergency Telephone Number Torrance CA 90501 USA 800 424 9300 Chemtrec Tel 310 972 7800 2 Hazards Identification EMERGENCY OVERVIEW DANGER N A Health Effects N A Primary Entry Routes Inhalation and eye contact Target organs Respiratory tract eyes Carcinogenicity IARC NTP and OSHA do not list chemical ingredients as a carcinogen HMIS Rating HMIS Rating Scale Health 1 Minimal 0 Flammability 0 Slight 1 Reactivity 0 Moderate 2 Protection N A High 3 Severe 4 HMIS Rating Notes Protec
37. sajseM pojeaa JO jesodsip pue 19jes Molle siodeA jenuajod au SBY AAN 01 UO Ado ouuoo aq JO aer sanno 10sso204d pue uoreaiasaid 5 onssi k ojogredoysiy JAN 01 ur eutmo po19jjnq 0 aPAyapjeuLioy snoonbe yea ssoooud juourjea eoruroqo s 80 XA TV3LLOYHN NADIOS ayy jo pousir qeiso UIMOJJOJ ou YIM ADO IONHOXLL QAIALL IO Se poziudooo1 Kqo1ou SI SIISEAA op Augop eurro y snoonby jo OY 104 S0 oumoo L UISIIS 9po Ajayeg pue LIH eru1ojie Jo 1700252 uonoos Jo suorstAoJd y 0 juensinq Agojouuoo eIUJOJI 0 4 1 Revised 06 18 2013 CAL EPA TECHNOLOGY CERTIFICATE Revised 06 18 2013 Section 5 APPLICATIONS AND ILLUSTRATIONS Product Applications and Procedures This section offers step by step written procedures and applications as well as instructional photographs for all of the Neutra Guard aldehyde neutralizing products Starting with Neutralex each of the products listed in this section is an integral part of a work practice control system designed to make disposal and exposure to aldehydes safer and in compliance with EPA and OSHA regulations Listed below are each of the Neutra Guard
38. stem ENEE 5 1 6 Aldehyde Waste Treatment Log T DOE 6 1 Revised 06 18 2013 ii Revised 06 18 2013 INTRODUCTION Intended Use The Tissue Tek Neutralex Aldehyde Control System is designed to neutralize formalin waste Aldehyde Neutralizing Agent As we settle into a new millennium the public concern for safe disposal of hazardous chemicals has become a national mandate Formaldehyde and glutaraldehyde disposal has become increasingly regulated by federal state and local agencies The challenge being posed is for safe effective remediation while keeping a watchful eye on cost containment In response to this challenge Sakura Finetek is pleased to offer a safe effective and economical solution for the drain disposal of most aldehyde solutions Neutralex technology offers this and so many other unique features e The ONLY Cal EPA certified technology for the treatment of formaldehyde e Complete neutralization in 15 minutes e Reaction does not produce any drain clogging polymer by products e No pH adjustment required prior to disposal e No messy liquids the easy to use powder form is conveniently packaged in pre measured pouches e Reaction is irreversible and environmentally safe In addition to providing the necessary documents to support the use of Neutralex this User s Handbook also offers information on other aldehyde control products that comprise the Neutra Guard system Neutralex is only on
39. sue Tek NEUTRALEX product code 4047 Synonym s N A Recommended Uses N A Manufactured For Sakura Finetek USA Inc Emergency Telephone Number Torrance CA 90501 USA 800 424 9300 Chemtrec Tel 310 972 7800 2 Hazards Identification EMERGENCY OVERVIEW DANGER Contact with acid solution of pH less than 4 releases sulfur dioxide gas which may be harmful or deadly if inhaled Health Effects May cause severe or deadly allergic reactions in some asthmatic and sulfur sensitive individuals Inhalation of dust or mist can irritate the respiratory tract Possible signs and symptoms of allergic reactions include bronchoconstriction sweating flushing hives rapid heart rate decreased blood pressure and anaphylaxis May irritate gastrointestinal tract Very large doses cause death violent colic diarrhea and depression May cause severe or deadly allergic reaction in some asthmatic and sulfur sensitive individuals HMIS Rating HMIS Rating Scale Health 2 Minimal 0 Flammability 0 Slight 1 Reactivity 0 Moderate 2 Protection N A High 3 Severe 4 HMIS Rating Notes Protection See section 8 3 Composition Information on Ingredients Hazardous Component CAS WEIGHT NIOSH ACGIH Specific Chemical Identity or OSHA TLV Trade secret chemical identity withheld Trade secret Trade secret 5 mg m3 5 mg m3 4 First Aid Measures Inhalation The patient should be transported away from exposure and
40. tion N A 3 Composition Information on Ingredients Hazardous Component Specific CAS WEIGHT NIOSH or ACGIH TLV Chemical Identity OSHA Trade secret chemical identity withheld Trade secret Trade secret 5 mg m3 5 mg m3 4 First Aid Measures Inhalation The patient should be transported away from exposure and brought to fresh air If necessary administer CPR keep warm and quiet Seek immediate medical attention Skin Contact Contaminated clothing should be removed immediately The affected body areas should be flushed with water for a period of approximately 15 minutes If symptoms persist seek medical attention Eye Contact Flush eyes immediately with water for 10 15 minutes If burning persists seek medical care Ingestion Induce vomiting to conscious victims and seek medical attention Unconscious victims should be placed on their left side with their head down Do not induce vomiting 5 Fire Fighting Measures Extinguishing Media Water fog regular foam dry chemicals or carbon dioxide Fire Explosion Hazards N A Fire Fighting Procedures Wear self contained breathing apparatus with full body protection Sensitivity to Static Discharge N A Hazardous Decomposition Products None Flash Point and Method Greater than 200 F Flammable Limits N A Auto Ignition Temperature N A 6 Accidental Release Measures Personal Precautions N A Protective Eguipment N A Emergency Procedures N A Env
41. trip to the color scale on the side of the bottle d The matching color will designate a number This is the residual aldehyde content in ppm of the treated formalin e Record these results in the Hazardous Waste Log that is discussed in step 10 9 If your aldehydic waste solution contains zinc ions a precipitate consisting of zinc hydroxide and other oxides will form The concentration of these precipitates will be measured in ppms Although these precipitates are generally considered non hazardous for disposal they should be removed by filtration This can be accomplished by using glass wool or a coffee filter The precipitate may be discarded or recycled 2 2 10 Discard detoxified aldehydic waste to a sanitary sewer system in accordance with your local Publicly Owned Treatment Works POTW discharge requirements It is important that you keep a log indicating the date of neutralization the employee that performed the procedure the volume of aldehydic waste treated and the analytical results of the neutralization A sample copy of this log can be found in Section 6 of the Neutralex User s Handbook Results After the 15 minute neutralization period is complete the resulting solution will have been neutralized and ready for disposal in accordance to the institutions wastewater permit or the local POTW Quality Control The neutralized solution should be verified for pH and residual aldehyde concentrations Aldehy
42. urnished on reguest A revised Material Safety Data Sheet will be furnished only if requested also in case of specification changes The above information which is accurate to the best of our knowledge and belief describes the safety aspects of our product but does not warrant any product properties The company gives no warranty as to the accuracy or completeness of such information als 7 MATERIAL SAFETY DATA SHEET SAKURA In accordance with ISO 11014 2009 Standard MSDS 0003384 01 Rev D Original Preparation Date 12 01 08 Revision Date 09 17 12 1 Chemical Product and Company Identification Product Name Tissue Tek NEUTRA PADS Synonym s N A Recommended Uses N A Manufactured For Sakura Finetek USA Inc Emergency Telephone Number Torrance CA 90501 USA 800 424 9300 Chemtrec Tel 310 972 7800 2 Hazards Identification EMERGENCY OVERVIEW DANGER N A Health Effects N A Primary Entry Routes Inhalation and eye contact Target organs Respiratory tract eyes Carcinogenicity IARC NTP and OSHA do not list chemical ingredients as a carcinogen HMIS Rating HMIS Rating Scale Health 1 Minimal 0 Flammability 0 Slight 1 Reactivity 0 Moderate 2 Protection N A High 3 Severe 4 HMIS Rating Notes Protection N A 3 Composition Information on Ingredients Hazardous Component Specific CAS WEIGHT NIOSH or ACGIH TLV Chemical Identity OSHA Trade secret chemical identity withheld Tra
43. void N A Incompatible Materials Strong oxidizers Stability Stable Hazardous Decomposition Products N A Hazardous Polymerization Cannot occur 11 Toxicological Information Acute Toxicity N A Skin Irritation Corrosion Burning Excessive exposure may cause mild skin irritation Pre existing skin conditions could be aggravated Absorption through skin is unlikely Eye Damage lrritation Depending on the quantity that comes in contact with an eye the injuries sustained may range from mild irritation to redness and burning Respiratory or Skin Sensitization N A Reproductive Cell Mutagenicity N A Carcinogenicity N A Reproductive Toxicity N A Specific Target Organ Toxicity single exposure Ingestion Single dose oral toxicity is slight Symptoms may include stomach irritation nausea and diarrhea Specific Target Organ Toxicity repeated exposure N A Aspiration Inhalation Hazard No reported effects 12 Ecological Information Aquatic Bioassay was conducted using guidelines prescribed in Static Acute Bioassay Procedure for Hazardous Waste for Samples result status pass 96 hour LCsq gt 750 mg l Ecotoxicity N A Persistence and Degradability N A Bioaccumulative Potential N A Mobility in Soil N A 13 Disposal Considerations Disposal Method Dispose of in accordance with all applicable local state and federal regulations 14 Transport Information UN Number N A UN Proper Shipping Name N A
44. yde as outlined below 2 4 Residual Aldehyde Test Procedure a Rinse the test vessel with the sample solution and fill to the 5mL mark b Immerse the reaction zone of the Aldehyde test Strip into the solution for 20 seconds c Shake off excess liquid from the strip then compare the reaction zone with color scale Revised 06 18 2013 Tissue Tek NEUTRALEX Procedure for Neutralizing Surgipath Decalcifier The following is the procedure for neutralizing Surgipath Decalcifier with Tissue Tek Neutralex There are two basic changes that represent a deviation from the normal Neutralex procedure First 10 sodium hydroxide is added to neutralize the formic acid Secondly the Decalcifier waste volume has been reduced to gallon per pouch of Neutralex These changes are implemented in the following procedure Operating Procedure Instructions for the neutralization of Surgipath Decalcifier Solution 1 Refer to the manufacturers MSDS for the safe handling of 1096 alcoholic formalin and OSHA mandated protective equipment e g safety goggles gloves impervious apron etc 2 For Decalcifier treatment all identifiable tissue must be separated from the liquid hazardous waste This shall be performed using the proper screen e g 80 mesh The liquid aldehydic waste is then collected in a calibrated reaction vessel Volumetric calibration can be in gallon or liter divisions preferably gallons 3 Add of a gallon
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