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SP500 series Open Housing Programmable Syringe

1. 3 d un F N E OP 03 Function Rate Direction 900 0 ml hr 17 25 ml Withdraw Q ii unction 14 wW t gz Function 15 Function E lag Ly 2 e 16 7 4 5 Example 5 Control from a High Low Pressure Sensor un Pumping c Rate Program lt A Pressure high sensor Output Pin Pressure low sensor ELE Pressure trigger points NE500 series manual 17 Revision 101101 NEXT gt gt ADVANCE www nextadvance com SP500 series OEM Programmable Syringe Pump This example demonstrates a Pumping Program whose control depends on an external sensor Assuming a pressure sensor that is configured to detect a high pressure point and a low pressure point the Pumping Program individually selects whether it will react to the high or low pressure point The Program Output pin on the TTL I O connector pin 5 is used to select the high or low pressure point When low the low pressure point is selected PHASE 01 and when high the high pressure point is selected PHASE 05 The Program begins by infusing continuously at 10 0 ml hr PHASE 02 while a background trap is set for the low pressure point PHASE 03 To create a delay when the pressure sensor is switched from high pressure to low pressure when the Program Output pin is set a small volume is pumped PHASE 02 06 before the background traps are set When the low pressure trap is tri
2. eeeeeeeeeeee nennen een eren nenne ente tn esee eene esten nnne ein 11 7 3 4 STOP PUMPING OPERATION AND END THE PROGRAM cn 11 7 3 5 JUMP TO PHASE FUNCTION etai ect eer eer a XE ra ede a teri ee E a E skred 11 7 3 6 DEFINE STARTING PHASE OF LOOP FUNCTION eee eene e enne enennne 11 7 3 7 DEFINE CONTINUOUS LOOP END FUNCTION cccccccccccscesessssescesccssessessseseeeseeseeees 11 7 3 8 DEFINE LOOP END AND LOOP REPETITIONS FUNCTION eee eee 11 7 3 9 PAUSE PUMPING FUNCTION ecnairc 12 7 3 10 JUMP TO PHASE IF EXTERNAL TRIGGER FUNCTION eere eene 12 7 3 11 SETUP EVENT TRIGGER JUMP PHASE FUNCTION eeeeenen eene eren enenn 12 7 3 12 ES NN SETUP EVENT SQUARE WAVE TRIGGER JUMP PHASE ccn 12 7 3 13 EVENT RESET PUNCGCTION intet rie eo etate eoi eai oSr i o eese meet eu re 12 7 3 14 SET TTL OUTPUT PIN FUNCTION cccccecsscecsssececssscececessseecesssseeecessseeecssseeeessaaes 13 1 3 15 BEBP BUNGTION ecce e ree SENSE EUG ritis e tios em domanaees sartecamnanees 13 7 4 PUMPING PROGRAM EXAMPLES ee ee ee ee eee enne tn ne eet tone sete enne e seen ness seen esee teen sees eaa 14 7 4 1 EXAMPLE 1 2 STEP RATE seede eiecti tue eee i ete Oed 14 74 2 EXAMPLE 2 REPEATED DISPENSES WITH SUCK BACK ee 14 74 3 EXAMPLE 3 RAMPING THE FLOW RATE ccccccccsssseceessscececsesceceeesseeeeessnseeeessaaeens 15 7 4 4 EXAMPLE 4 COMPLEX DISPENSES WITH EXTERNAL
3. command is the communications time out This time out in seconds is the time between the reception by the pump of consecutive valid communications packets Each time a valid communications packet is received the time out is reset If the time out elapses a pump alarm will occur stopping the pump and the Pumping Program The buzzer will sound if alarms are enabled alerting the user The communications time out timer will not restart until the next reception of a valid packet In addition there is a 0 5 second packet inter byte time out While receiving a communications packet and before its complete reception if a delay of 0 5 seconds occurs between bytes the incomplete packet will be discarded With the Auto Alarm feature whenever a pump alarm occurs such as a pump stall a response packet with the alarm status information will automatically be transmitted Until the Safe Mode is disabled each time power is applied to the pump the pump defaults to the Safe mode of communications but the communications time out timer will not be enabled until the first reception of a valid packet Although the communications time out timer is not enabled the Auto Alarm feature will be enabled NE500 series manual 24 Revision 101101 NEXT gt gt ADVANCE www nextadvance com SP500 series OEM Programmable Syringe Pump Therefore the pump will be in an Auto Alarm only communications mode When power is applied to the pump or if the system shou
4. Function 2 Function Rate 800 0 ml hr Infuse Function OUT 0 Function EVN 07 Function 800 0 ml hr Infuse i i 3 3 4 NE500 series manual 20 Revision 101101 NEXT HDVRHNCE www nextadvance com unction AS 01 Function Function 10 PAS 10 Function 11 EVN 01 Function 12 PAS 10 Function JMP 01 oO 13 NE500 series manual 21 SP500 series OEM Programmable Syringe Pump Function 1000 0 ml hr 0 25 ml Revision 101101 NEXT gt gt ADVANCE www nextadvance com SP500 series OEM Programmable Syringe Pum 8 RS 232 Communications The SP500 series Syringe Pump can communicate with any computer software NM package or device with an RS 232 communications port TE Be Ja mA 8 1 Connection and Networking EE LI the side of the pump are 2 square RJ 11 phone jack style sockets Connect the RS 232 cable into the socket labeled Computer Connect the other end to the serial port on the computer or other control device Turn power off to the pump and the computer before connecting cables If the pump is part of a pump network connect a pump network cable between the socket labeled Pump Network on the first pump and the socket labeled Computer on the next pump in the network Repeat for each pump in the network connecting the Pump Network socket of one pump to the Computer socket on the next pump in the network Up
5. The units of the accumulated infusion and withdrawal volumes and the Volume to be Dispensed are set according to the diameter setting From 0 1 to 14 0 mm Syringes smaller than 10 mL Volume units are uL From 14 01 to 50 0 mm Syringes greater than or equal to 10 mL Volume units are mL 5 2 Start Stop Triggers Start Command RUN Stop Command STP The Pumping Program can be started or stopped from any of the different sources The RUN command or the TTL I O Operational Trigger input Each can control the Pumping Program s operation 5 3 Operating the Pump When a start trigger is given the Pumping Program begins to operate starting with Phase 1 If the current Program Phase specifies a pumping rate the pump will begin pumping The pumping direction will depend on the Phase setup The volume dispensed can be queried with the DIS command While pumping the pump will pump continuously in the current Program Phase unless a Volume to be Dispensed is set or an Event trigger is set If a Volume to be Dispensed is set the Program Phase will be complete after the set volume has been infused or withdrawn measured from the start of the Phase 5 4 Pumping Rate Command RAT lt float gt lt units gt Sets queries the pumping rate and rate units 5 4 1 Changing the Pumping Rate and Direction While Pumping Command RAT lt float gt NE500 series manual 6 Revision 101101 NEXT gt gt ADV
6. Hz Edge changes to the Pumping Direction and Operational Trigger inputs must occur at least 50 ms apart Falling edge refers to a logic high to logic low transition Rising edge refers to a logic low to a logic high transition To guarantee recognition of logic levels voltages on the input lines must be within the following ranges TTL logic low 0 0 to 0 9 V logic high 1 3 5 to 5 25 V The Vcc and Ground pins pins 1 and 9 are for logic reference only To assure proper voltage levels the Ground pin should always be connected to the signal ground of a sensing or controlling device that is attached to any other pin on the TTL I O connector The Vcc pin should not be used to source current The TTL I O pins are defined as follows NE500 series manual 32 Revision 101101 NEXT gt gt ADVANCE www nextadvance com SP500 series OEM Programmable Syringe Pump Pin Definition Type Function 1 Vcc 5V Reference Logic high reference 2 o ional Tri I Configurable start stop operational trigger input perational Trigger Apt Foot Switch Falling edge Start or stop trigger Level Falling edge Stop trigger Rising edge Start trigger Start only Falling edge Start trigger 3 Pumping Direction Input Changes pumping direction according to setup dr rE dr dU Falling edge Infuse Withdraw Rising edge Withdraw Infuse 4 Event Trigger Input Event input or user definable input 5 Program Output Output Program controlled output o
7. I O connector Valid value 5 Program Output pin Query is not applicable TTL INPUT QUERY IN n Queries TTL level of pin on TTL I O connector Set is not applicable lt n gt Indicates pin number on TTL I O connector Valid values 2 3 4 and 6 Response TTL level BUZZER BUZ 0 1 lt n gt Sets queries buzzer Set 0 Turn buzzer off 1 Turn buzzer on if lt n gt specified If lt n gt 0 buzzer beeps continuously otherwise buzzer beeps lt n gt times if lt n gt not specified buzzer sounds continuously Query response 0 1 0 Buzzer off 1 Buzzer is on continuously or beeping FIRMWARE VERSION QUERY VER Response NE50 lt n gt V n lt n gt where lt n gt lt n gt is current model and firmware version number Set is not applicable NE500 series manual 30 Revision 101101 NEXT gt gt ADVANCE www nextadvance com SP500 series OEM Programmable Syringe Pump MASTER PROGRAM RESET RESET Clears program memory and resets communication parameters to Basic mode and address 0 This is a special system command that will be accepted by the pump regardless of its current address 8 6 Getting Started With RS 232 Before beginning to develop pump control software for a computer first setup and experiment with the pump s communication After attaching the pump to the computer run a terminal emulation Program on the computer A generic terminal emulator supplied as standard software
8. M s hardware electronics and firmware are copyrighted Copyright 2004 all rights reserved 1 1 Warnings and Cautions D Read the users manual No user serviceable parts are inside Disconnect power from the pump when connecting or disconnecting cables Do not immerse the pump in liquid Install on a stable surface Keep hands and loose clothing away from the pumps moving parts The pump can automatically start when the Pumping Program is operating or when attached to an external control device Prevent liquids from entering openings of the pump Do not push objects of any kind into the chassis openings except for appropriate cables and connectors ZN If the pump becomes damaged do not use unless certified safe by a qualified technician Damage includes but 1s not excluded to frayed cords and deterioration in performance Discharge static from control cables before connecting by touching the cable to ground Before touching the pump discharge static by touching ground 1 2 Disclaimer Next Advance Inc makes no representations or warranties expressed statutory or implied regarding the fitness or merchantability of this product for any particular purpose Further Next Advance Inc is not liable for any damages including but not limited to lost profits lost savings or other incidental or consequential damages arising from ownership or use of this product or for any delay in the performance of its obligations under the w
9. Phase Function 7 4 7 Example 7 Dispensing with Complex Synchronization Restart on Event Trigger or 10 seconds Repeat if Program Input low Infuse until Event Trigger TTL High TTL Low TTL Program Ouput Event Trigger Infuse Event Trigger Withdraw This example demonstrates a complex interaction with external equipment such as synchronizing with another syringe pump The Program includes a variety of interactions with external equipment which demonstrates the various control possibilities of the SP500 series pumps The Pumping Program begins by canceling any previous event traps PHASE 01 and raising the Program Output TTL line PHASE 02 After 5 0 ml has been dispensed at 800 ml hr PHASE 03 the Program Output TTL line is lowered PHASE 04 sending a synchronization signal to another device The pump then continues to pump at 800 ml hr PHASE 06 until a synchronization signal is received at the Event Trigger TTL input causing the Program to jump to Phase 7 PHASE 05 The pump then withdraws 0 25 ml PHASE 07 pauses for 1 second PHASE 08 then repeats this process if the Program Input TTL line is low PHASE 09 otherwise it continues with the next Phase Next the pump pauses for 10 seconds PHASE 10 Then it pauses again for the lesser of another 10 seconds PHASE 12 or until an Event Trigger occurs PHASE 11 The Program then restarts PHASE Function 1 EVR
10. SP500 s operation please take the time to familiarize yourself with the basic concepts below 2 3 4 5 6 Parts of the Pump 7 Syringe Retainer Bracket End Plate Anti Siphon Plate Adjustment Knob Drive Nut Button Anti Siphon Plate Drive Screw Syringe Retainer Thumbscrew 2 one on each side NE500 series manual 8 V Slot on Syringe Holder Block 9 Syringe Holder Block 10 Syringe Holder Clamp 11 Guide Rod 2 guide rods 12 Pusher Block Revision 101101 NEXT gt gt gt ADVANCE www nextadvance com Parts of a Syringe Plunger Flange Terminology Pumping Program Pumping Program Operating Pumping Program Stopped Pumping Program Paused Pumping Program Resumed Executed Program Phase Phase Number Currently Selected Function Pumping Rate Function Function Parameter Start Trigger NE500 series manual Plunger SP500 series OEM Programmable Syringe Pump Barrel Barrel Flange The sequence of automated operations entered into the pump This could be as simple as a single function to pump at a single infusion rate continuously When the pump is started with the Start Stop key or any other source the pump begins performing the operations in the Pumping Program until the Pumping Program either stops automatically or the pumped is stopped when the Start Stop key is pressed or from any other source While performi
11. SYNCHRONIZATION 16 7 4 5 EXAMPLE 5 CONTROL FROM A HIGH LOW PRESSURE SENSOR 17 7 4 6 EXAMPLE 6 AUTOMATED DISPENSING WITH SYNCHRONIZATION cn 19 7 4 7 EXAMPLE 7 DISPENSING WITH COMPLEX SYNCHRONIZATION s es 20 8 RS 232 COMMUNICATIONS csssccccssssscccessscccesssccccesssccccesssccecesssccccesssssecessssseees 22 8 1 CONNECTION AND NETWORKING sccccssssssccesssscccssssccccssssccccesssccccesssccecesssccecesssseeceses 22 8 2 RS 232 PUMP NETWORK CONFIGURATION ssccccssssscsessssscccssssccccssssccecesssccecessscceceses 22 8 3 RS 232 tao 22 8 3 1 RS 232 GENERAL SYNTAX LEGEND eeeeeeree eene nennen eren en nennen 23 8 3 2 RS 232 PROTOCOL BASIC MODE Qu cccccccesssscececssscececssscececsssceceesssceeecssusesecssaaeees 24 8 3 3 RS 232 PROTOCOL SAFE MODE ieeeeeee eee eene enne nennen nennen en nennen 24 8 3 4 RS 232 PROTOCOL BASIC AND SAFE MODE COMMON SYNTAX 25 8 4 COMMAND ERRORS AND ALARMS ccccssssscccesssccccesssccccessscccessssccccesssccecesssscecessssceeeses 25 8 5 RS 232 COMMAND SET ito e eee eese ee ee eod eee eo pe EH ee Sac aeu ops e e vene coos sooccseedescseedveseccevses 26 8 5 1 PROGRAM FUNCTION COMMANDS ccccccesssscecesssececessceecssaeeeceeaceecessseecssneeeenses 26 8 5 2 PUMP OPERATIONAL COMMANDS ccsccccssssscecesssececesssceecseaeeecesaeeecsesseecessteeeeesns 28 8 5 3 CONFIGURATION AND SETUP COMMANDS ceeceee eren e ener
12. as with the Pause in Phase 5 or the Loop in Phase 6 the function is entered in 2 steps First select the function and store it Then enter the associated data Function Volume 750 ml hr 2 0 ml nfuse Function Direction 750 ml hr 0 25 ml Withdraw J i nction unction zt n Function PAS 90 oi E falle e o 4 ge w I 5 4 i Phase Function LOP 03 Function Function Function Volume 50 ml hr 225ml nfuse Function Direction 750 ml hr 0 25 ml Withdraw P unction az td I e 7 4 3 Example 3 Ramping the Flow Rate Phases E 2 4 ON Phases Phases 25 5 8 9 11 o c E Time Note Graph is representative only Pumping rate increments and decrements in steps Continuously ramp up and down the pumping rate Starting at 200 ml hr the pumping rate will increment to 250 ml hr in 1 0 ml hr steps after every 0 1 ml has been dispensed Then the pumping rate will decrement to 150 ml hr in 1 0 ml hr steps after every 0 1 ml has been dispensed Finally the pumping rate is incremented back to 200 ml hr in 1 0 ml hr steps after every 0 1 ml has been dispensed then the process is repeated Phase Function Rate Volume Direction Phase Function NE500 series manual 15 Revision 101101 NEXT gt gt ADVANCE www nextadvance com SP500 series OEM Programmable Syringe Pump Function INC Infuse Function LOP 50 Fu
13. be Dispensed and pumping direction Use the RAT VOL and DIR commands to set or review the Rate Function s setup For continuous pumping set the Volume to be Dispensed to 0 0 7 3 2 Increment Rate Function Command FUN INC The increment and decrement functions operate the same as the RATE function except that the specified rate is added INC or subtracted DEC from the current pumping rate The current pumping rate when the function is executed is the base pumping rate for the function If no base pumping rate exists such as when executing a pause function or when the Pumping Program is first started a Program error will occur and the Program will stop The pumping rate units will be the same as the base pumping rate and therefore cannot be set or queried with the pumping rate increment or decrement value As with the RATE function a Volume to be Dispensed and pumping direction can be specified for the increment and decrement functions When used within a Program loop the pumping rate can be incremented or decremented in small step NE500 series manual 10 Revision 101101 NEXT gt gt ADVANCE www nextadvance com SP500 series OEM Programmable Syringe Pump intervals 7 3 3 Decrement Rate Function Command FUN DEC The decrement function subtracts the specified rate from the current pumping rate For a full description see section 7 3 2 Increment Rate Function 7 3 4 S
14. each dispensed from a different pump plus other equipment and sensors Pumping Programs can be designed for each pump which enable multiple pumps to synchronize with each other and the other equipment and sensors using a cable connected to the TTL I O connectors of each pump When the Pumping Program is started either from the keypad TTL I O connector or from RS 232 the Pumping Program will begin with Phase 1 of the Program After the completion of each Phase the pump NE500 series manual 9 Revision 101101 NEXT gt gt ADVANCE www nextadvance com SP500 series OEM Programmable Syringe Pump will immediately start the next consecutive Phase This linear sequence of Phases can be altered by certain functions that direct the Pumping Program to continue operation with a different Phase number Some functions can change the order of operation conditionally based on external events 7 1 How to Enter Pumping Programs Start by organizing your pumping requirements into specific actions and conditions that can then be programmed into Phases For more advance programming methods common groups of Phases can be grouped together and repeated multiple times using looping and jump functions The current values of the pumping rate optional Volume to be Dispensed and pumping direction all refer to the currently selected Phase Use the command PHN to set the current phase To change the Program Function of the currently selected progra
15. response packet following the lt prompt gt field The following are the error responses lt command error gt gt lt error gt lt error gt gt Command is not recognized only NA Command is not currently applicable OOR Command data is out of range COM Invalid communications packet received IGN Command ignored due to a simultaneous new Phase start When an alarm occurs the alarm must be acknowledged before any data is changed or the pump is started Alarms are acknowledged by the user clearing the alarm message on the keypad or the alarm status being sent in response to any valid RS 232 command An alarm message sent automatically in the Safe Mode will not clear the alarm condition This is to verify that the alarm message was sent to a receptive host NE500 series manual 25 Revision 101101 NEXT gt gt ADVANCE www nextadvance com SP500 series OEM Programmable Syringe Pump such as after a power failure when both the computer and the pump were reset In this case the pump will most likely send its reset alarm message before the computer has finished booting 8 5 RS 232 Command Set All data changed from RS 232 is stored in the non volatile memory except for changes to the pumping rate while pumping All Program Phase Data refers to the currently selected Program Phase Use the Phase select command PHN to query or select the current Phase A Phase consists of the pumping rate Volume to be Dispensed an
16. ANCE www nextadvance com SP500 series OEM Programmable Syringe Pump Except with some complex Pumping Programs the pumping rate can be changed while the pump is operating To change the pumping rate while pumping use the RAT command to send a new rate A new rate set while pumping will not be stored in non volatile memory Rate units cannot be changed while pumping If the new rate is valid it will take affect immediately The pumping direction can be changed while pumping if the Volume to be Dispensed is 0 0 The direction command DIR will immediately change the pumping direction and store the pumping direction in the current Program Phase Also changing the pumping direction changes the accumulated Volume Dispensed according to the new pumping direction 5 5 Pumping Direction Command DIR INF WDR Sets the direction of pumping to Infuse INF or Withdraw WDR 5 6 Dispense Volume Target and Continuous Pumping Command VOL lt float gt To set a dispense volume use the VOL command The current Pumping Phase will continue to pump infusing or withdrawing until the set volume has been pumped For continuous pumping set the volume target to 0 Command VOL 0 5 7 Volume Dispensed Volume is computed based upon the syringe inside diameter setting The volume is accumulated separately for infusion and withdrawal The volume dispensed for infusion and withdrawal can be queried with the DIS command Th
17. EE EEEE TE 2 2 1 GLOSSARY OF TERMINOLOGY AND CONCEPTS cccccsscscscscccccccssscscsccccccccessccccscsccececees 2 3 SE DU EP E E r vesvecstuaneuseseaseesevondecceseevss seassoousessocsesevsnsocsesoosees 5 4 LOADING SYRINGES seisisseicicissescicsscassccsssevacevesadsccsisaviccvssadiccedsaveccvesadiccb vavocevesascccsseavece 5 5 OPERA TION fem 6 5 1 SYRINGE INSIDE DIAMETER esevevvveveeessvnnnnnnnnenesensnnnnnnennnnesensnnnnnnnnnennsennnnnnensenenenennnnnsenee 6 5 1 1 DEFAULT VOLUME UNITS erevevvvevsvrvevevenenensnsnenenenenensneneneneneneneneneneneneneneneneneneneneeeneee 6 5 3 START STOP TRIGGERS cvsssscsscssscescdscsssssedsoscncdvossoosessceessdsees sess oessadsesssoscecoseesessssssesecesees 6 5 3 OPERATING THE PUMP wesscessccicccdeccdccacecesccccaceteccoctascccsecedcssceneidadesestseessueudecssdetcessstessdeeets 6 54 PUMPING RATE esis seccaceesssscaesseeseseuetsessscesssoscnesoossasseesosceessedssseses0sseeseysobdssevesseodenceseseses es 6 5 4 1 CHANGING THE PUMPING RATE AND DIRECTION WHILE PUMPING 6 5 5 PUMPING DIRECTION se iee ee sensa reso oa ae ee eo sea re one e eo pe nea re Va sk ae ease pa eiae ea auae anie eae E OE Ua sa aee e ena adn 7 5 6 DISPENSE VOLUME TARGET AND CONTINUOUS PUMPING eee eese eese eese eese eese eese en 7 5 7 VOLUME DISPENSED PEE 7 5 8 RESUMING WHEN PAUSED cccsccssscssssssssccccccesssssscnsccccsccsscesconececcsccsscessonscescescessssonecess 7 59 PUMP STALLED RR ERREUR sess
18. NEXT HDVHNCE www nextadvance com SP500 series OEM Programmable Syringe Pump PUMPING DIRECTION DIR INF WDR REV Set query pumping direction INF Infuse WDR Withdraw REV Reverse pumping direction Applicable with all Program Phase functions Cannot be set when the Pumping Program is operating and the Volume to be Dispensed is non zero The pumping direction cannot be changed if an alarm condition exists Query response INF WDR 8 5 2 Pump Operational Commands START PUMPING PROGRAM RUN Starts the Pumping Program operation If the Pumping Program was paused then the Pumping Program resumes at the point where it was stopped Otherwise the Pumping Program starts from Phase 1 The pump cannot be started if an alarm condition exists STOP PUMPING PROGRAM STP If the Pumping Program is operating the pump will be stopped and the Pumping Program will be paused If the Pumping Program is paused the stop command will cancel the pause and reset the Pumping Program VOLUME DISPENSED DIS Queries volume dispense only Set not applicable Response I float W float volume units gt Where I lt float gt refers to the infusion volume dispensed and W lt float gt refers to the withdrawn volume CLEAR VOLUME DISPENSED CLD INF WDR Sets the Infused or withdrawn volume dispensed to 0 Command is only valid while the Pumping Program is not operating INF Infusion v
19. NEXT gt ADVANCE www nextadvance com SP500 series Open Housing Programmable Syringe Pump Models SP500 SP501 SP510 SP511 SP570 M EEEO AAA S WARNING NOT FOR CLINICAL NE500 series manual USE ON HUMANS Revision 101101 NEXT gt gt ADVANCE www nextadvance com SP500 series OEM Programmable Syringe Pump Quick Start Instructions Quick start instructions assume that the pump was not previous programmed with a multiple Phase Pumping Program e Plugin the pump e Attach the computer cable to the Computer connection on the RJ 11 connector e Start the terminal emulator program on the computer Baud Rate 19 200 Data frame 8N1 e Note Each command sent to the pump must have a carriage return 0x0D at the end but space characters are optional and will be ignored e Note Wait for the response from each command before sending the next command Setup Pumping Parameters Set the Syringe Inside Diameter e Where nn nn is the syringe inside diameter Send the command DIA nn nn Set the Pumping Rate e Where nn nn is the pumping rate and xx is the rate s units Send the command RAT nn nn xx Rate units xx value mL hr MH uL hr UH mL mn MM uL mn UM e If the pumping rate is out of range the response message to the computer will include 7OOR Set the Volume to be Dispensed or Continuous Pumping e Where nn nn is the volume to be dispensed send the command VOL nn nn If t
20. NTROLLER 3 5 isierite rcs re rveeisia vv eisee v etis biete o Reese esu ine 38 10 4 4 FOOT SWITCH EC m 38 10 4 5 FIRMWARE UPGRADE ccccccccssssccecssscesecssscececesssececssssececssssecccsssaeeecsssseeecssaeeeeseaaes 38 10 5 TROUBLESHOOTING AND MAINTENANCE cccccccsssssccesssscccscssccccecssccccecssccesesssceeceses 38 10 6 SPECIFICATIONS er E 39 10 6 1 MECHANICAL amp ELECTRICAL eeeeeeeeeeeen nennen nee enne en entere ARA 39 10 6 2 OPERATIONAL undret tee etes rectas ee eret eie te mte ein dad 39 10 7 CUSTOM APPLICATIONS oe ee eee e ense ee eee ee Sepe ee es oe ue ee ee eas vae e eec Ee ee eua au S 39 NE500 series manual iv Revision 101101 NEXT HDVHNCE www nextadvance com SP500 series OEM Programmable Syringe Pump 1 General Information Thank you for purchasing the SP500 SP501 SP510 SP511 570 M OEM Programmable Syringe Pump With the SP500 series syringe pump you will be able to perform simple infusions or implement a complex automated dispensing system Please familiarize yourself with the SP500 series operation by reading this user s manual For future reference record the serial number located on the rear of the pump and the date of purchase Next Advance Inc can be contacted at Phone USA 800 738 1681 International 518 674 3510 FAX 518 674 0189 Email info nextadvance com www nextadvance com This Operating Manual and the SP500 SP501 SP510 SP511 SP570
21. S If no unpaired loop start function exists Phase 1 is used as an implied unpaired loop start This pairing defines the loop and the range of Phase numbers between the paired loop functions defines the scope of the loop When a loop end function is executed Program operation continues with the loop start function paired with the loop end function There are 2 loop end functions Loop continuous FUN LPE and Loop for a preset number of iterations FUN LOP nn indicated by nn Each time a paired loop end function is executed an iteration of the loop is complete With the FUN LOP nn function after nn number of loop iterations the defined loop is complete and Program execution continues with the next Program Phase after the loop end function The loop is then no longer defined or paired While executing Phases within the scope of a defined loop another loop start and loop end can be paired and become a defined loop within the scope of the first loop which is referred to as the outer loop The new loop being referred to as the inner loop The pairing of a loop within a paired loop is referred to as nesting of loops with each loop being one nested layer for the duration of the loops pairing Loops can be nested for a total of 3 layers deep Loops can only be nested within the scope of an outer loop NE500 series manual 11 Revision 101101 NEXT gt gt ADVANCE www n
22. T gt ADVANCE www nextadvance com SP500 series OEM Programmable Syringe Pump 5 Operation Before the pump can be operated the pumping data must be setup At minimum the syringe inside diameter and a non zero pumping rate needs to be set The operation of the pump can then be started from the TTL I O connector or from RS 232 computer control All data that is set will be stored in the pump s non volatile memory meaning that the new value will not be lost the next time that power is applied to the pump The only exception is when the pumping rate is changed while the Pumping Program is operating In this case the new pumping rate will not be stored in non volatile memory In general numeric data are floating point data consisting of up to 4 digits plus 1 decimal point and is referred to in the command descriptions as lt float gt data For example 123 4 12 3 and 12 34 are acceptable formats for floating point data 5 1 Syringe Inside Diameter Set with command DIA lt float gt The syringe inside diameter can only be set while the Pumping Program is stopped Valid syringe diameters are from 0 1 mm to 50 0 mm If the diameter is out of this range the response will be OOR Changing the syringe diameter will not zero any current settings Section 10 1 Syringe Diameters and Rate Limits is a representative list for reference of syringe diameters for various syringe manufacturers and syringe sizes 5 1 1 Default Volume Units
23. arranty due to causes beyond its control Next Advance Inc also reserves the right to make any improvements or modifications to the product described in this manual at any time without notice of these changes Next Advance Inc products are not designed intended or authorized for use in applications or as system components intended to support or sustain human life as a clinical medical device for humans or for any application in which the failure of the product could create a situation where personal injury or death may occur All brand and product names used in this manual are the trademarks of their respective owners NE500 series manual 1 Revision 101101 NEXT gt gt ADVANCE www nextadvance com SP500 series OEM Programmable Syringe Pump 1 3 Warranty Next Advance Inc warranties this product and accessories for a period of two year parts and labor from the date of purchase The repaired unit will be covered for the period of the remainder of the original warranty or 90 days whichever is greater A return authorization number must be obtained from Next Advance Inc before returning a unit for repair Warranty covered repairs will not be performed without a return authorization number At the option of Next Advance Inc a defective unit will be either repaired or replaced This warranty does not cover damage by any cause including but not limited to any malfunction defect or failure caused by or resulting from unauthorized se
24. ase data gt Set event trigger trap EVS lt phase data gt Set event square wave trigger trap EVR Event trigger reset BEP Sound short beep OUT lt TTL level gt Set programmable output pin PUMPING RATE RAT float rate units gt Set query pumping rate rate units gt UM ul min MM ml min UH ul hr MH ml hr Applicable only with Rate Data Functions When setting the pumping rate if the current Phase s function is not RATE then rate units is not applicable While pumping the pumping rate can only be set if the current Phase function is RATE and the next Program Phase s function to be executed is not INCR or DECR Also while pumping rate units can not be set The new pumping rate will only be stored in non volatile memory if the Pumping Program is not operating When the pumping rate is queried while pumping the response will be the current pumping rate and units Otherwise the response will be the rate setting and units if applicable With the INCR and DECR functions these two responses are not the same VOLUME TO BE DISPENSED VOL float Set query volume to be dispensed Applicable only with Rate Data Functions Can only be set when the Pumping Program is not operating The volume units are set according to the current syringe diameter setting Query response float volume units NE500 series manual 27 Revision 101101
25. be queried from an attached computer using the RS 232 IN command The output logic level of pin 5 can be set with the RS 232 OUT command NE500 series manual 34 Revision 101101 NEXT gt gt ADVANCE www nextadvance com SP500 series OEM Programmable Syringe Pump 10 Appendix 10 1 Syringe Diameters and Rate Limits Syringe Inside Maximum Minimum Size Diameter Rate Rate Manufacturer cc mm ml hr pl hr 60 6 59 1699 23 35 Monoject ef 1i2 7 387 6 5 326 60 26 64 1705 23 44 10 is e eoo 8 244 eo 29 7 2120 29 13 Syringe Inside Maximum Minimum Size Diameter Rate Rate uL mm ul hr pl hr Hamilton Microliter SGE NE500 series manual 35 Revision 101101 NEXT gt gt ADVANCE www nextadvance com SP500 series OEM Programmable Syringe Pump 10 2 RS 232 Command Summary lt command gt gt DIA lt float gt PHN lt phase data gt FUN lt phase function gt lt phase function gt gt RAT INC DEC STP JMP lt phase data gt PRI PRL lt count data gt LOP lt count data gt LPS LPE PAS lt number data gt PAS n n IF lt phase data gt EVN lt phase data gt EVS lt phase data gt EVR BEP OUT 0 1 RAT lt float gt UM MM UH MH VOL lt float gt DIR INF WDR REV RUN phase data STP DIS CLD INF WDR SAF lt n gt lt n gt lt n gt AL lt on o
26. d the pumping direction A packet without a command is interpreted as a status query The addressed pump responds with a status only response packet Except where noted a command without any parameters is a query command The response packet data will include the requested data In general the query response data will be in the same format as the parameters for setting the command For example the query diameter command DIA will respond with lt float gt as the response data Otherwise the command is a set command If the data was set a status only response packet will be sent If the data was not set the response packet will include an error lt command error gt message indicating why the data was not set All commands are upper case but in Basic Mode will be accepted as lower case plus spaces and control characters will be ignored This facilitates manually entering commands using a terminal emulator lt command gt gt DIAMETER DIA lt float gt Set query inside diameter of syringe Set is only valid when the Pumping Program is not operating Setting the syringe diameter also sets the units for Volume to be Dispensed and Volume Dispensed 8 5 1 Program Function Commands The following commands are relevant to the currently select Program Phase Note During a Pumping Program s operation the currently selected Phase can change automatically PHASE NUMBER PHN phase data Set que
27. dcoseesdsesssescecoseessvsesbessecosess 7 6 SETUP CONFIGURATION 0s0sssssssssssssssssssssssssesssssssssssssssesssesssesssssssssssssssssssessseees 8 61 POWER FAILURE MOBDE veo eo eo ranae o ee eau n ao aaa ea eo ao oo nu Vau ae eu e ipeo noua auae en Uo door nuni a n eoi en Uu 8 62 AUDIBLE ALARM ENABLE wiicsscssosceessessoseessescscsvsosscsdsosescesessenssdcosesssesessensdcosesossoesssssecosess 8 63 TTL I O OPERATIONAL TRIGGER CONFIGURATION eeeseeesnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnee 8 6 4 TTL I O DIRECTIONAL CONTROL INPUT CONFIGURATION eeeseensnnnnnnnnnnnnnnnnnnnnnnnnnnee 9 6 5 PUMP MOTOR OPERATING TTL OUTPUT CONFIGURATION s esesesnsnnnnnnnnnnnnnnnnnnnnnnnnnnen 9 7 PUMPING PROGRAM c ccccccccsssssssssssssssscscssccccscssscssscssscsscssssssssssssssssssssssssssssssssooees 9 7 1 HOW TO ENTER PUMPING PROGRAMS ccccccsssssccccccccccsssssccscccccccesescscccsccccscessccssccsees 10 72 CLEARING THE PUMPING PROGRAM eseoevovnvevesessnsnnnnnneenenessnsnnnnnneenennnsnnnennnnnenennnsnnnene 10 73 PROGRAM FUNCTION DESCRIPTIONS cccscsssscsssssssscsccccecccssscssceccccesscssscsscecescsssssseseees 10 7 3 1 RATE FUNCTION smeden ee dene ek leie 10 NE500 series manual ii Revision 101101 NEXT gt gt ADVANCE www nextadvance com SP500 series OEM Programmable Syringe Pump 7 3 2 INCREMENT RATE FUNCTION ccccsessseceseceeeessnscceceeecsesesseaceeceeeeseeesssaeaeeeeecseneneas 10 7 3 3 DECREMENT RATE FUNCTION
28. ddress will be stored in the pump s non volatile memory and will take affect immediately Once the set address command is sent the pump will only respond to commands sent to the set address To query a pump s current network address send the command ADR without any parameters The pump will respond with its current pump address in the response packet s data field 8 3 RS 232 Protocol When the pump is used in a multi pump network configuration precede each command with a pump address Pumps will ignore all commands that do not have their defined network address If the network address is not specified in the command the address will default to 0 After a command is sent to the pump the pump will not accept any further communications until the current command has been processed Completion of the command processing is indicated when the first byte of the response packet is transmitted NE500 series manual 22 Revision 101101 NEXT HDVHNCE www nextadvance com SP500 series OEM Programmable Syringe Pump Communications to and from the pump use the following data frame Supported RS 232 Data Frames Baud rate 19200 Frame 10 bit data frame 8N1 Start bit 1 Data bits 8 Stop bits 1 Parity None Every command received by a pump in the network is acknowledged by the pump with a response packet that includes a status character indicating the current operational state of the pump Two packet protocols are supported Basic a
29. e Volume Dispensed accumulations for infusion and withdrawal are reset to 0 when A The pump is powered on B The syringe diameter is changed C From the RS 232 clear Volume Dispensed command CLD D The accumulated Volume Dispensed rolls over from 9999 to 0 5 8 Resuming When Paused If the Pumping Program is stopped before the completion of the Pumping Program the response prompt will change to P indicating that the Pumping Program is paused While paused starting the pump again will resume the Pumping Program where it was stopped This means that the Pumping Program will continue at the point in the Phase where it was stopped and the Volume to be Dispensed will still be referenced from when the Program Phase first started Pause is exited by sending a stop command STP or changing any setting When the Pumping Program is started again it will start from the beginning Phase 1 5 9 Pump Stalled Model SP501 only When the operation of the motor is impeded due to excessive force needed to drive the syringe the pump will stop pausing the Pumping Program and a stall alarm will occur The buzzer will sound continuously if alarms are enabled Also if the RS 232 Safe Mode is enabled an NE500 series manual 7 Revision 101101 NEXT gt gt ADVANCE www nextadvance com SP500 series OEM Programmable Syringe Pump auto alarm message will be sent to an attached computer Sending any command will stop the buzz
30. e cable is attached to the Computer connection on the pump If the Basic communications mode is used check if the pump is in Safe communications mode See section 8 3 RS 232 Protocol for instructions on how to change the communications mode Verify the pump s network address Pusher block makes a snap or click sound when the pump is started This is a normal condition When the pusher block is manually moved the drive nut may not have been fully engaged on the drive screw The sound heard is the drive nut engaging on the drive screw Pump doesn t stop after dispensing a set volume The pump was previously setup with a multiple Phase Pumping Program To simply dispense a fixed volume at a fixed pumping rate the second Program Phase must be the Stop function See section 7 1 How to Enter Pumping Programs for instructions on changing the Pumping Program Pump stops pumping after a period of time A dispense volume has been set Verify that the dispense volume is set to 0 NE500 series manual 38 Revision 101101 NEXT gt gt ADVANCE www nextadvance com SP500 series OEM Programmable Syringe Pump 10 6 Specifications 10 6 1 Mechanical amp Electrical Syringe sizes Number of syringes Motor type Motor steps per revolution Microstepping Advance per step Motor to drive screw ratio Drive screw pitch DC connector Voltage at DC connector Amperage Power supply type Dimensions Weight 10 6 2 Operatio
31. e right of the decimal point volume units UL ul microliters ML ml milliliters TTL level gt 1 TTL high level 0 TTL low level lt on off gt gt 1 On enabled 0 Off disabled lt phase data gt gt lt n gt lt n gt count data gt gt n lt n gt lt number data gt gt lt n gt lt n gt lt text gt gt any printable character lt text gt lt gt lt n gt lt n gt gt 0 11213 41516 7 819 lt byte gt gt one byte of any data O NE500 series manual Program Phase number Valid values 1 to 41 Valid values 1 to 99 Valid values 0 to 99 Floating point digits Digits One byte of data expressed as Oxhh where hh is the data in hexadecimal Is defined by Syntax expands to next level of expansion 23 Revision 101101 NEXT gt gt ADVANCE www nextadvance com SP500 series OEM Programmable Syringe Pump lt gt Non terminal syntax expansion Optional syntax O Required syntax Or Choose one of the syntax options None Syntax expands to nothing lambda production Description of syntax expansion 8 3 2 RS 232 Protocol Basic Mode Command syntax to pump lt basic command protocol gt gt lt command data gt lt CR gt Response syntax from pump lt basic response protocol gt gt lt STX gt lt response data gt lt ETX gt In the Basic communications mode a master slave protocol is used whereby the p
32. er and clear the alarm When the problem causing the pump motor to stall has been corrected the Pumping Program can be resumed by any start trigger TTL input or RS 232 6 Setup Configuration The following configuration parameters can be set or queried woe The values for n are 0 for off 1 for on Command Description PFn Power Failure mode where n is the current setting ALn Alarm mode where n is the current setting TRG aa Operational Trigger configuration where aa is the current configuration DIN n Directional control input setup ROM n Pump motor operating TTL output configuration 6 1 Power Failure Mode Command PF lt n gt lt n gt Setting 0 Disabled 1 Enabled When enabled if the Pumping Program was operating when power to the pump was disrupted the Pumping Program will automatically start operating when power is reconnected to the pump CAUTION The Pumping Program will start operating from the beginning of the Pumping Program Phase 1 regardless of what part of the Pumping Program was operating when the power was disrupted When the SP500 series syringe pump is used as a component in an automated infusion withdrawal dispensing system a Pumping Program can be designed to automatically synchronize the pusher block at the start of the Pumping Program This would be accomplished using attached sensors that send signals to the Pumping Program 6 2 Audible Alarm Enab
33. et ene eterne 29 8 5 4 GENERAL CONTROL AND STATUS COMMANDS eene eene eren en enne 30 8 6 GETTING STARTED WITH RS 232 4 eee eere ee eese enne eee tn sesta ense ette ense eese ense este tn aestas 31 9 LOGIC INTERFACE TTL INPUT AND OUTPUT ee esee eee en nonnul 32 9 1 TTL I O OPERATIONAL CONTROLS ee ee eene eee enne eee tone eee en sees etos eese e enne este en esee eaa 33 92 TTL I O CONTROL FROM THE PUMPING PROGRAM eee enne nonne etta nasa a es ee tetao 34 9 3 TTL I O CONTROL FROM RS 232 eere ee esee en nee tn nose ee enne ette enne eese enne esee ense essa 34 10 APPENDIX dq M se MGMM r H t Pm tet mtn 35 10 1 SYRINGE DIAMETERS AND RATE LIMITS eee ee ee ee eee eee erento nene eee eate toto see e esee 35 NE500 series manual iii Revision 101101 NEXT gt gt ADVANCE www nextadvance com SP500 series OEM Programmable Syringe Pump 10 2 RS 232 COMMAND SUMMARY essvssessvsvesensvnvesennnsvesennnnvesennnneesennnneesennnneesensnneesennnneeee 36 10 3 RS 232 PUMP NETWORK CONNECTOR WIRING ee eese ee eese enne ee ee enne sese tone esee tane eee 37 10 4 ACCESSORIES m M 37 10 4 1 RS 232 NETWORK CABLES eene nennen enr sn en nns e en ense e enter seen tenis 37 10 4 2 AUTOMATION CABLE RECIPROCATING PUMPS CONTROL CABLE c 37 10 4 5 VALVE CO
34. extadvance com SP500 series OEM Programmable Syringe Pump 7 3 9 Pause Pumping Function Command FUN PAS nn n n gt If nn is non zero the Pumping Program will pause pumping stops pumping for nn seconds After the pause interval the next Program Phase will be executed nn can range from 00 to 99 or 0 1 to 9 9 seconds For pauses longer than the 99 second maximum pause for this function put the pause function within a Program loop A Program section with the following functions in consecutive Phases FUN LPS FUN LPS FUN PAS 60 FUN LOP 60 FUN LOP 24 will pause the Pumping Program for 24 hours If nn is 00 then the Pumping Program pauses and waits for a start trigger to resume the Program After the start trigger the Program will resume with the next Phase The start trigger can be from any source the TTL I O Operational Trigger or from RS 232 If alarms are enabled the buzzer will beep continuously while waiting for the start trigger 7 3 10 Jump to Phase If External Trigger Function Command FUN IF nn The IF function conditionally alters the Pumping Program s execution based on an external signal When executed if the TTL I O Program Input pin pin 6 is low level then the Pumping Program continues operation with Phase number nn Otherwise the Pumping Program continues operation with the next Phase 7 3 11 Setup Event Trigger Jump Phase Function Command FUN EVN nn T
35. ff gt PF lt on off gt TRG FT LE ST DIN 0 1 ROM 0 1 OUT 5 0 1 IN 2 3 4 6 BUZ 0 1 lt n gt VER ADR n lt n gt RESET NE500 series manual Syringe inside diameter Program Phase number Program Phase function Pumping rate RATE Increment rate INCR Decrement rate DECR Stop pump STOP Jump to Program Phase JP nn Program Selection Input Pr In Program Selection Label definition Pr nn Loop to previous loop start nn times LP nn Loop starting Phase LP ST Loop end Phase LP EN Pauses pumping for nn seconds PS nn Pauses pumping for n n seconds PS n n If Program input low jump to Program Phase IF nn Set event trigger EV nn Set event square wave trigger ES nn Event trigger reset EV RS Sound short beep BEEP Set programmable output pin OUT n Pumping rate Volume to be Dispensed Pumping direction Starts the Pumping Program Stop pauses the Pumping Program Query volume dispensed Clear volume dispensed Safe communications mode Alarm mode Power failure mode Operational trigger mode Directional input control mode Pump Motor Operating TTL output mode Set TTL output level Query TTL input level Buzzer control Query firmware version Network address system command valid regardless of current address Clears program memory and resets communication parameters sy
36. ggered the pump sets the high pressure trap PHASE 07 and begins to increment the flow rate The flow rate is incremented in 1 0 ml hr steps with every 0 25 ml dispensed PHASE 08 10 Ifthe high pressure trap hasn t as yet been triggered the flow rate will max out at 25 0 ml hr while waiting for the high pressure trap PHASE 11 When the high pressure point is reached the pump immediately will drop down to 10 0 ml hr PHASE 02 and once again wait for the low pressure point Phase Function OUT 0 te Volume irection 0 ml hr 0 005 Infuse Function am unction VN 05 Rate irection 10 0 ml hr 0 0 ml off Infuse nction am nction UT 1 unction irection 0 0 ml hr 0 005 Infuse 5 2 E trj zou cot form i i i i i i i i i i gt unction Function te irection 0 25 ml Infuse Function e Function 10 LOP 14 e e Rate irection 25 0 ml hr 0 0 ml off Infuse Function NE500 series manual 1 loo Revision 101101 NEXT gt gt ADVANCE www nextadvance com SP500 series OEM Programmable Syringe Pump 7 4 6 Example 6 Automated Dispensing with Synchronization Power Failure Mode Pumping Program Restart at Power Up Syng VN TT MIME omm UT Refill Event Trigger from Syringe Filled Sensor Jump to Phase 3 NE500 series manual 19 Revision 101101 NEXT gt ADVANCE www nextadvance com SP500 series OEM Programmable Syringe Pump
37. he Event function sets a background event trap that is triggered by an external signal This one time background trap or interrupt stays set during the Pumping Program s entire execution until it is triggered or reset This function has no other affect on the operation of the pump until it is triggered The event is triggered when either 1 A falling edge high to low TTL transition occurs on the TTL Event Trigger input pin 4 or 2 A low level on the Event Trigger input pin at the time when the function is executed When triggered the current operation of the pump and the Pumping Program is interrupted and the Pumping Program immediately continues operation jumps to with Phase number nn After being triggered the event trigger is reset If an event trigger function 1s executed while another event trap is still set the new event trigger will replace the previous event trap 7 3 12 ES nn Setup Event Square Wave Trigger Jump Phase Command FUN EVS nn The Event Square Wave function operates the same as the EVN Event function with the exception of the triggering conditions This function will trigger on either the rising or the falling edge of the TTL Event Trigger input pin 4 Therefore a square wave function on the inupt pin can be used to toggle the pump between 2 sections of a Pumping Program An example of this would be a Pumping Program that switched between a slow and fast pumping rate control
38. he volume to be dispenses is 0 then the pump will pump continuously e Note The units for the volume to be dispensed will be mL or uL depending on the syringe size At or below 14 00 mm syringe diameter volume units are uL Above 14 00 mm syringe diameter volume units are mL Set the Pumping Direction e For infusion send the command DIR INF For Withdrawal send the command DIR WDR Load the Syringe e Press in the white drive nut button to move the pusher block e Insert the syringe plunger in the pusher block slot e Insert the syringe barrel flange in the flange brackets with the syringe barrel holder on the syringe Tighten the flange brackets onto the syringe flange Tighten the pusher block screw Operating the Pump Start the Pump e Send the command RUN Stop the Pump e Send the command STP Query the Pump Status e Send just a carriage return to the pump The pump will respond with a status prompt When Pumping e The pumping rate can be changed e With continuous pumping the pumping direction can be changed NE500 series manual i Revision 101101 NEXT gt gt ADVANCE www nextadvance com SP500 series OEM Programmable Syringe Pump 1 GENERAL INFORMATION 00s0sssssssssssssssssssssssssssssssssssssssssesssesssssssessssssssssssssseees 1 1 1 WARNINGS A AND CAUTIONS D EE 1 12 DISCLAIMER de 1 1 3 WARRANTY EEE ooro E stae D s sosatie iS 2 2 OVERVIEW AEEA RAE ER
39. ld reset a system reset alarm occurs The Auto Alarm feature therefore alerts the host computer that a pump reset has occurred 8 3 4 RS 232 Protocol Basic and Safe Mode Common Syntax transmitted data gt command data response data command data gt lt address gt lt command gt To pump response data gt lt address gt status lt data gt command error gt From pump status gt prompt alarm Operational state of pump prompt gt I Infusing W Withdrawing S Pumping Program Stopped P Pumping Program Paused T Pause Phase U Operational trigger wait user wait alarm gt A alarm type Alarm alarm type gt R Pump was reset power was interrupted S Pump motor stalled T Safe mode communications time out E Pumping Program error O Pumping Program Phase is out of range lt address gt gt n lt n gt Pump network address 0 to 99 lt data gt gt lt text gt Response to command lt CR gt gt 0x0D Carriage return lt STX gt gt 0x02 lt ETX gt gt 0x03 lt CRC 16 gt gt lt byte gt lt byte gt 16 bit CCITT CRC of lt transmitted data gt high byte low byte lt length gt gt lt byte gt Number of bytes remaining in packet including this byte 8 4 Command Errors and Alarms If a command received by the pump is not recognized or the data is invalid an error message will be in the lt data gt field of the
40. le Command AL lt n gt lt n gt Setting 0 Disabled 1 Enabled When alarms are enabled the buzzer will be sounded as follows Pumping Program ended Continuous beeping Pumping Program paused for start trigger Continuous beeping Alarm condition such as pump motor stalled Steady alarm Any command sent to the pump will stop the alarm 6 3 TTL I O Operational Trigger Configuration Command TRG lt aa gt lt aa gt as below in settings Configures how the TTL I O Operational Trigger pin 2 will control the Pumping Program s operation See sec 9 1 TTL I O Operational Controls NE500 series manual 8 Revision 101101 NEXT gt ADVANCE www nextadvance com SP500 series OEM Programmable Syringe Pump Falling edge starts or stops the Pumping Program Control Falling edge stops the Pumping Program Rising edge starts the Pumping Program ST Start Only Falling edge starts the Pumping Program 6 4 TTL I O Directional Control Input Configuration Command DIN lt n gt Configures how the TTL input Pumping Direction pin 3 will control the pumping direction See sec 9 1 TTL I O Operational Controls Reciprocating Pumps Falling edge Infuse Rising edge Withdraw Used for 2 pumps operating in opposite directions 1 Dual Pump Falling edge Withdraw Rising edge Infuse Used with 2 pumps operating in the same direction 6 5 Pump Motor Operating TTL Output Configuration Com
41. led by a square wave input 7 3 13 Event Reset Function Command FUN EVR NE500 series manual 12 Revision 101101 NEXT gt gt ADVANCE www nextadvance com SP500 series OEM Programmable Syringe Pump Event Reset cancels a previously set event trap 7 3 14 Set TTL Output Pin Function Command FUN OUT n Set Program Output TTL I O output pin 5 to level n If n 0 the output pin will be set low If n 1 the output pin will be set high 7 3 15 Beep Function Command FUN BEP Sounds a short beep NE500 series manual 13 Revision 101101 NEXT gt ADVANCE www nextadvance com SP500 series OEM Programmable Syringe Pump 7 4 Pumping Program Examples 7 4 1 Example 1 2 Step Rate a Q o N ml hr Rate 2o 30 ml Dispensed Infuse 5 0 ml at 500 ml hr then infuse 25 0 ml at 2 5 ml hr Then stop the pump Phase Function Rate Volume Direction 500 ml hr Phase Function Rate Volume Direction 25ml hr 25 0 mi Phase Function To send this program to the pump send the following sequence of commands PHN 1 FUN RAT RAT 500 MH VOL 5 0 DIR INF PHN2 FUN RAT RAT 2 5 MH VOL 25 0 DIR INF PHN3 FUN STP 7 4 2 Example 2 Repeated Dispenses with Suck Back ml hr Rate NE500 series manual 14 Revision 101101 NEXT gt gt ADVANCE www nextadvance com SP500 series OEM Programmable Syringe Pump When entering a function with associated data such
42. m phase use the FUN command When finished sending the data for the current Phase use the PHN command to select the next program phase to be set Now all pumping data will refer to next currently selected Phase Data for the current Phase can now be entered Continue selecting Phase numbers and entering the infusion or control setup for each Phase of the Pumping Program The entire Pumping Program will be stored in non volatile memory Use the STOP function FUN STP to stop the pump and end the Pumping Program If the Pumping Program does not operate the pump continuously the last Phase of the Pumping Program must be a STOP function unless the last Phase number is the maximum Phase number When the Pumping Program is started with the TTL I O input or RS 232 command the Pumping Program will begin operating from Phase 1 Very complex dispensing Programs can be created with the Program functions available Section 7 3 contains a detailed description of all the functions 7 2 Clearing The Pumping Program To clear out the pumping program memory and reset communication parameters send the command RESET 7 3 Program Function Descriptions 7 3 1 Rate Function Command FUN RAT This is the most basic function to simply command the pump to pump to dispense and a specific rate Defines a pumping function with a fixed pumping rate This function defines a pumping setup consisting of the pumping rate optional Volume to
43. mand ROM lt n gt Configures the functionality of the Pump Motor Operating TTL output pin TTL pin 7 Setting Mode lt n gt Sets the output to logic high only when the motor is operating pumping Sets the output to logic low when the motor is not operating or when the Pumping Program is executing a pause timer or is stopped Sets the output to logic high when the motor is operating pumping or when the Pumping Program is executing a pause timer Sets the output to logic low when the Pumping Program is stopped 7 Pumping Program A Pumping Program is simply a pre defined sequence of actions or functions which guarantees consistent and precise operation of the pump automatically and with or without any user intervention A Pumping Program can be as simple as continuous pumping at a fixed infusion rate Or a Pumping Programs could consist of a pumping rate and direction of pumping for a specified volume then switch to another pumping rate Also a Program can interact with external devices through the TTL I O connector make decisions or stop pumping for a period of time Programs are broken into individual operations called Phases Each Phase consists of a function that can be a control function or pumping function A pumping function such as RATE consists of a pumping rate optional Volume to be Dispensed and the pumping direction Complex dispensing systems can be designed involving multiple liquids
44. n 101101 NEXT HDVRHNCE www nextadvance com SP500 series OEM Programmable Syringe Pum 9 Logic Interface TTL Input and Output Ex Q i CAUTION NOT FOR CLINICAL USE ON HUMANS NEW ERA PUMP SYSTEMS WWW SYRINGEPUMP COM 631 249 1392 MODEL NO U Farmingdale NY info syringepump com NE 1000 VOLTS Hz 11 VDC AMPERAGE RS 232 To Network I To Computer TIL 1 0 A 0 75 SERIAL NO EU i eee o C A Figure 1 Rear of Pump On the rear of the pump is a DB 9 connector below the TTL I O label which is used for TTL I O The logic signals on this connector permit bi directional control with external equipment Control input TTL logic levels must be held steady for a minimum of 100 ms to be recognized To minimize the possibility of false signals caused by glitches and ringing which could be caused by the closure of mechanical switches TTL control inputs are software filtered With a sampling period of 50 ms glitches of less then 100 ms are filtered out Edge detection requires the detection of a change in TTL levels With a minimum of 100 ms to detect a level an edge requires a minimum of 200 ms to be detected Since the next level change can be detected in 100 ms creating another edge the maximum edge to edge frequency is 10
45. nal Maximum speed Minimum speed Maximum pumping rate Minimum pumping rate Maximum force Number of Program Phases RS 232 pump network RS 232 baud rate Up to 60 cc 1 Step motor 400 1 8 to 1 2 depending on motor speed 0 2126 uM to 0 8504 uM depending on motor speed 15 28 20 revolutions 2 mm center positive 12 VDC at full load 750 mA at full load Unregulated linear external wall adapter country and power source specific 9 1 2 x 4 1 4 x 4 1 8 High 24 13 cm x 10 8 cm x 10 5 cm 2 2 lbs 1 0 kg 5 1005 cm min 0 004205 cm hr 1699 ml hr with a B D 60 cc syringe 0 73 ul hr with a B D 1 cc syringe 35 Ibs at minimum speed 18 lbs at maximum speed 4 100 pumps maximum 19200 Syringe inside diameter range 0 100 to 50 00 mm 10 7 Custom Applications Ge 7 1 1 1 NE e ay For specialized and OEM applications contact your dealer or Next Advance Inc Custom modifications can be made to the mechanics or the firmware NE500 series manual 39 Revision 101101
46. nction LPS Function DEC Function LOP 99 Function LPS Function Direction INC Infuse Function LOP 50 t Function t DEC Infuse 10 1 Function 12 JMP 02 7 4 4 Example 4 Complex Dispenses with External Synchronization i t Syringe ee 4 Refill A more complex dispensing example this Program contains different pumping requirements including dispenses with multiple pumping rates The first set of 3 dispenses drops down to a lower pumping rate during the dispense When each dispense is completed the buzzer beeps to alert the operator then the pump waits for a start trigger before starting the next dispense The next set of 3 dispenses have a fixed time interval of 60 seconds between dispenses After the last set of dispenses the syringe is refilled by the amount infused 17 25 ml Then the buzzer beeps to alert the operator to the start of the first set of dispenses The process is then repeated Phase Function Rate Volume Direction NE500 series manual 16 Revision 101101 NEXT HDVHNCE www nextadvance com SP500 series OEM Programmable Syringe Pump Function Function PAS 00 Function Function lume irection 750 0 ml hr 5 ml nfuse Function Direction 300 0 ml hr Infuse i e J e E c w O t 5 d em N unction P wo es 5 i nction Function PAS 60 nction Direction 500 0 ml hr 3 75 ml Infuse unction
47. nd Safe The enabled communications protocol is stored in non volatile memory and therefore will be in affect at power up Safe Mode provides a safer communications protocol than Basic Mode Safe Mode detects corrupted data and loss of communication as well as automatically transmitting status packets when an alarm occurs Considering that the 19200 baud rate communicates at 52 us per bit a small glitch on the RS 232 cable flipping a single bit can convert a transmitted infusion rate of 100 ml hr into 900 ml hr the need for the Safe Mode in a production environment is evident However Basic Mode is excellent for simplifying early development of a control program While in the Basic Mode the pump will accept either communications protocol Basic or Safe Though the response packet will be in the current communications mode This allows a computer s communication s driver to be designed with just one mode A Safe Mode communications driver can send a SAF command to the pump in the Safe Mode protocol while the pump is in Basic Mode The response to the SAF command enabling Safe Mode will then be in the Safe Mode protocol 8 3 1 RS 232 General Syntax Legend The following syntax expansion legend is common to all syntax expansions Except where indicated all command and response characters are ASCII data float gt f float Floating point number Maximum of 4 digits plus 1 decimal point Maximum of 3 digits to th
48. ng the operations defined in the Pumping Program the Pumping Program is referred to as operating While Operating the motor can be pumping or stopped according to the Pumping Program The motor is stopped and the pump is not operating the Pumping Program The Pumping Program has been stopped but can be resumed at the point where it was stopped Continuing a Pumping Program that was Paused before the completion of the Pumping Program The Pumping Program continues at the point where the Pumping Program was stopped The pump has performed a single operational Phase as defined in the Pumping Program A single defined operation in the Pumping Program A Program Phase s numerical sequence location in the Pumping Program Each Pumping Program Phase instructs the pump to perform a particular operation Only one Program Phase is selected at any one time This is the current Phase Each Phase is set to one function The set function of the current Phase is the currently selected function Each Pumping Program function instructs the pump to perform a particular operation Ifthe Phase s operation instructs the SP 500 to pump then associated with that Phase is the Phases pumping information When Program Entry Mode is exited the Rate Volume and pumping direction keys refer to the currently selected Program Phase s function The Program functions that are associated with pumping information are referred to as Pum
49. odels extra powerful error detection loss of communication motor for higher flow rates and more force detection and automatic transmitting of l itions SP570 M model extra precise motor for AGO microfluidics TTL I O with software filtered control f i inputs to eliminated glitch ingi Infusion and withdrawal volumes separately AE ee ned endog the control inputs accumulated Biecrafamdbie dispense vohis Configurable TTL operational trigger P Failure Mode Restarts the Pumpi Programmable Phases allowing complex ONE else Made Rec e pope pumping applications and interaction with external devices NE500 series manual Program after a power interruption Audible Alarm Revision 101101 NEXT HDVRHNCE www nextadvance com Table showing the various models and features SP500 series OEM Programmable Syringe Pump Microfluidics Standard Stall Detection Option Standard Motor SP500 SP501 Extra Powerful Motor SP510 SP511 Extra Precise Motor for SP570 M aa 2 1 Glossary of Terminology and Concepts When a device has as many features as the SP500 and similar models understanding its operation could be a daunting task at first By understanding the key concepts and terminology used in this manual the operation of the SP500 will become quite intuitive Every effort has been made to design the SP500 with a consistent and intuitive user interface To facilitate and enhance your understanding of the
50. olume WDR Withdrawn volume Query is not applicable NE500 series manual 28 Revision 101101 NEXT HDVHNCE www nextadvance com SP500 series OEM Programmable Syringe Pump 8 5 3 Configuration and Setup Commands New settings for any of the following commands will be stored in the non volatile memory SET PUMP NETWORK ADDRESS ADR lt address gt Set query pump network address address gt n lt n gt lt address gt Valid range 0 to 99 This is a special system command that will be accepted by the pump regardless of its current address Once set the pump will only respond to commands with the set address ENABLE SAFE COMMUNICATIONS MODE SAF time out gt Set query Safe communications mode setting time out gt n n lt r gt time out gt Valid range 0 to 255 if time out 0 then Basic communication mode is set disabling Safe mode If time out gt 0 then Safe communications mode is enabled After the reception of this command valid communications must be received every time out gt seconds ALARM SETUP AL lt on off gt Set query alarm setup mode Set alarm enables or disables alarm buzzer mode POWER FAIL SETUP PF lt on off Set query Power Failure mode Set Power Failure enables or disables Power Failure mode TTL I O OPERATIONAL TRIGGER SETUP TRG trigger setup Set Query TTL I O Operational Trigger input configuration TTL I O Operational Trigger i
51. ors In this setup with the pumps configured for this operation one pump will infuse while the other pump withdraws When one pump changes direction the other pump changes direction When one pump starts the other pump starts When one pump stops for any reason the other pump stops NE500 series manual 37 Revision 101101 NEXT gt gt ADVANCE www nextadvance com SP500 series OEM Programmable Syringe Pump 10 4 3 Valve Controller Part ADPT VALVE INTERFACE 1 For one pump Part ADPT VALVE INTERFACE 2 For two pumps includes CBL TTL 1 Provides a control interface for your electronic valves Attach your electronic valves and the interface will control the activation of the valves The 2 pump interface is used to create a continuous infusion refill system 10 4 4 Foot Switch Part ADPT 2 Allows the pump to be operated from a foot switch Attaches to the TTL I O connector 10 4 5 Firmware Upgrade Contact your dealer to determine the current available version of the pumps internal firmware 10 5 Troubleshooting and Maintenance Maintenance Periodically a small amount of all purpose oil should be applied to the guide rods The mechanism should be kept clean to prevent impeded operation No other special maintenance or calibrations are needed RS 232 Communications If no RS 232 communications 1s possible or garbled responses are received from the pump check the following Verify the correct communications port and that th
52. ping Rate functions Certain functions which do not instruct the SP 500 to pump require additional data This additional data displayed with the function is the function s parameter The Pumping Program may be started or stopped from multiple sources These are the TTL I O Operational Trigger input or from a command received through the RS 232 connection 4 Revision 101101 NEXT gt gt ADVANCE www nextadvance com SP500 series OEM Programmable Syringe Pump 3 Setup Place the pump on a stable surface Plug the connector end of the power supply into the power plug located on the PCB on the side of the pump See section 9 Logic Interface TTL Input and Output for a diagram of the connectors on the pump After power is applied to the pump the buzzer will beep Next the Pumping Program can be entered Before the Pumping Program can be operated the pump needs the measurement of the inside diameter in millimeters of the syringe that will be loaded The syringe diameter is entered using the DIA command Finally the syringe can be loaded and the pump started 4 Loading Syringes The syringe is loaded by securing the barrel and the pusher flange as follows 1 Loosen the 2 thumbscrews on the syringe retainer bracket 2 Press in fully the white drive nut button on the pusher block releasing the block Taking care not to drag the drive nut on the drive screw slide the block away from the syringe holder pro
53. r user definable output 6 Program Input Input Program conditional input or user definable input 7 Pump Motor Operating Output RUN 0 High Pumping Low Not pumping RUN 1 High Pumping or Pause timer Low Not pumping 8 Pumping Direction Output High Infuse Low Withdraw 9 Ground 0V Reference Logic low reference 9 1 TTL I O Operational Controls While the user is changing settings or configuration from the keypad external control by the Pumping Direction and Operational Trigger inputs will be ignored These controls will also be ignored if an alarm condition exists Operational Trigger Pin 2 The input signal on this pin controls the operation of the Pumping Program Its functionality is user configurable Use the TRG command to configure this input pin See Section 06 3 TTL I O Operational Trigger Configuration Each option Foot Switch Level Control and Start Only define when the Operational Trigger input is activated When activated the trigger emulates a Start Stop key Foot Switch Operates like a Start Stop key whereby each falling edge contact to ground either starts or stops pauses the Pumping Program Level Control Falling edge stops pauses the Pumping Program Rising edge starts the Pumping Program This configuration can be used with a contact closure timer or in an automation setup allowing logic level control over the operation of the pump Start Only Falling edge starts the P
54. rvice or parts improper maintenance operation contrary to furnished instructions shipping or transit accidents modifications or repair by the user harsh environments misuse neglect abuse accident incorrect line voltage fire flood other natural disasters or normal wear and tear Changes or modifications not approved by Next Advance Inc could void the warranty The foregoing is in lieu of all other expressed warranties and Next Advance Inc does not assume or authorize any party to assume for it any other obligation or liability 2 Overview The SP500 series is a general purpose single syringe pump capable of infusion and withdrawal It is controlled from a microcontroller based system which drives a step motor allowing a large range of pumping rates calibrated to the inside diameter of the loaded syringe The syringe is driven from a drive screw and drive nut mechanism Features Infusion and withdrawal pumping of syringes up to 60 cc Non volatile memory of all operating parameters and Pumping Program Pumping rates from 0 73 ul hr with a 1 cc to RS 232 bi directional control 2120 ml hr with a 60 cc SP500 and SP501 E i models Built in pump network driver Pump network supports up to 100 pumps and SP501 and SP511 models Stall detection other devices Automatically st h ing i MI REEL TR Wo E E Two modes of RS 232 control Basic and impeded R R Safe Safe mode provides communication SP510 and SP511 m
55. ry currently selected Program Phase Set Currently selected Phase is set to phase data Previous Phase is stored in non volatile memory and the requested Phase is recalled from the non volatile memory Set is only valid if the Pumping Program is not operating Query response phase data Currently selected Phase PUMPING PROGRAM FUNCTION FUN phase function Set query the Pumping Program Phase s function This command is relevant to the currently selected Phase Set is only valid if the Pumping Program is not operating For a more detailed description of Program commands see sec 7 3 Program Function Descriptions NE500 series manual 26 Revision 101101 NEXT gt gt ADVANCE www nextadvance com SP500 series OEM Programmable Syringe Pump lt phase function gt gt Rate Data Functions When a Phase s function is set to a Rate Data Function use the RAT VOL and DIR commands to setup the pumping parameters RAT Pumping rate RATE INC Increment rate INCR DEC Decrement rate DECR Non Rate Data Functions STP Stop pump STOP JMP lt phase data gt Jump to Program Phase LOP count data gt Loop to previous loop start nn times LPS Loop starting Phase LPE Loop end Phase PAS number data PAS n n IF lt phase data Pauses pumping for nn seconds Pauses pumping for n n seconds If Program input TTL pin low jump to Phase EVN lt ph
56. s no affect When the mode is set to dual pumps DIN 1 then if the current pumping direction is withdraw a rising edge sets the direction to infuse If the current pumping direction is infuse a falling edge sets the direction to withdraw Otherwise this input pin has no affect Dual and reciprocating pumping systems are created using 2 pumps attached with the accessory cable CBL TTL 1 The output pin provides an output signal to external devices indicating the direction of pumping A logic low indicates withdraw and a logic high indicates infuse For example this pin can be used to control an external valve allowing the syringe to refill from a reservoir 9 2 TTL I O Control from the Pumping Program Various Pumping Program functions can define how the pump reacts to levels on the TTL I O connector or set output levels These are summarized in the following table Pumping TTL I O Control Pin Pin Action Program Function FUN OUT lt n gt Program Output Set logic level output to n FUN EVN nn Event Trigger 4 Low level when executed or a falling edge afterward until canceled causes a jump to Phase nn FUN EVS nn Rising or falling edge triggers a jump to Phase nn Trigger FUN IF lt nn gt Program Input 16 Low level causes a jump to Phase nn FUN PAS 00 Operational Trigger Trigger activation resumes Program operation 9 3 TTL I O Control From RS 232 The logic levels of pins 2 3 4 and 6 can
57. s set to trigger setup gt trigger setup gt FT Foot switch trigger falling edge LE TTL Level trigger rising and falling edge ST Start only trigger falling edge TTL I O DIRECTIONAL CONTROL INPUT SETUP DIN 0 1 Set query directional control input setup Settings gt 0 Falling edge Infuse Rising edge Withdraw Use this setting with the CBL TTL 1 reciprocating pump cable to create a 2 pump continuous infusion system 1 Falling edge Withdraw Rising edge Infuse Use this setting with the CBL TTL 1 reciprocating pump cable to create a 2 pump dual pumping system NE500 series manual 29 Revision 101101 NEXT gt gt ADVANCE www nextadvance com SP500 series OEM Programmable Syringe Pump PUMP MOTOR OPERATING TTL OUTPUT CONFIGURATION ROM lt on off gt Set query Pump Motor Operating TTL output configuration TTL pin 7 Settings gt 0 Output is logic high only when the pump motor is operating pumping 1 Output is logic high when the pump motor is operating pumping or when the Pumping Program is executing a pause timer SET KEY BEEP BP lt on off gt Set query key beep mode Set key beep enables or disables key beep mode This command is not relevant to models SP500 series pumps 8 5 4 General Control and Status Commands TTL I O OUTPUT SETTING OUT lt n gt TTL level Sets TTL level on user definable output pin on the TTL I O connector lt n gt Indicates pin number on TTL
58. stem command valid regardless of current address 36 Revision 101101 NEXT HDVHNCE www nextadvance com SP500 series OEM Programmable Syringe Pump 10 3 RS 232 Pump Network Connector Wiring RS 232 To Network To Computer V V J ff DL TI D RCV from network TXD to computer TXD to network RCV from computer PC Com Port Connectors 25 Pin 9 Pin 3 Receive 2 Receive Connect to pump TXD 2 Transmit 3 Transmit Connect to pump RCV 9 Ground 5 Ground Connect to pump GND 10 4 Accessories 10 4 1 RS 232 Network Cables RS 232 Network Primary Cable 7 foot cable part CBL PC PUMP 7 25 foot cable part CBL PC PUMP 25 Cable to connect a pump or the first pump in a pump network to a standard personal computer s serial port with a DB 9 or DB 25 connector Included with this cable is a 9 pin to 25 pin converter RS 232 Network Secondary Cable 7 foot cable part CBL NET 7 25 foot cable part CBL NET 25 Cable to connect additional pumps after the first pump to the pump network 10 4 2 Automation Cable Reciprocating Pumps Control Cable Part CBL TTL 1 Using two SP 1000 family syringe pumps this cable creates an automated continuous operation pumping system whereby one pump is refilling while the other is dispensing This cable is attached to two SP 1000 family syringe pumps via their TTL I O connect
59. to 100 SP500 series pumps can be network together along with other pumps from the SP 1000 family of pumps to one communications port on a computer See section 9 Logic Interface TTL Input and Output for a diagram of the rear of the pump When communicating with a pump in a multi pump network each preceding pump in the network must be powered on Each pump in the network needs a unique network address to identify the pump to the computer Network addresses are from 00 to 99 If the network consists of only 1 pump set the pump s address to 0 the factory default address Also each pump needs to be set to the same baud rate as the computer The default baud rate is 19 200 8 2 RS 232 Pump Network Configuration If only one pump is being used leave the address at the default of 0 Up to 100 pumps from the SP 1000 family of pumps can be attached to a computer in a single pump network The network address is set using the command ADR nn where nn is the pump s network address from 0 to 99 If only one pump is in the network leave the addres at the default address of 0 This will simplify communications because the address can be left off the commands sent to the pump To set the network address individually attach each pump to the computer Disconnect the network cable from the Network connector on the pump Using the ADR nn command send a unique address to each pump from 0 to 99 This operation only has to be performed once The set a
60. top Pumping Operation and End The Program Command FUN STP Stops the pumping operation and stops the Pumping Program The Pumping Program will begin at Phase I when started again An implicit Stop function is executed when the Program exceeds the maximum Phase number during operation If alarms are enabled the buzzer will beep continuously when the Pumping Program stops 7 3 5 Jump to Phase Function Command FUN JMP nn The Jump function alters the consecutive operation of Program Phases When executed the Pumping Program will continue operation with Phase nn 7 3 6 Define Starting Phase of Loop Function Command FUN LPS Defines the start of a Program loop For a full description of Program looping see sec 7 3 8 Define Loop End and Loop Repetitions Function 7 3 7 Define Continuous Loop End Function Command FUN LPE Loops to the most recently executed unpaired loop start Phase or Phase if none This function allows a section of the Program to be repeated continuously For a full description of Program looping see sec 7 3 8 Define Loop End and Loop Repetitions Function 7 3 8 Define Loop End and Loop Repetitions Function Command FUN LOP nn Repeats execution of the defined loop nn times Loop starts and loop ends are uniquely paired during looping When an unpaired loop end function is executed it is paired with the most recent unpaired loop start function executed FUN LP
61. ump will only transmit in response to a received command When the pump receives the lt basic command protocol gt lt command data gt will automatically be stripped of all space and control characters and all text will be converted to upper case This simplifies communications with the pump when commands are being manually typed in from a generic terminal emulator To return the pump to Basic mode when in the Safe mode send the following packet to the pump 0x2 0x8 SAFO 0x55 0x43 0x3 8 3 3 RS 232 Protocol Safe Mode Command syntax to pump safe command protocol gt lt STX gt length command data CRC 16 lt ETX gt Response syntax from pump safe response protocol gt lt STX gt length response data CRC 16 gt lt ETX gt Safe mode uses a more structured protocol including detection of corrupted communications communications time outs and auto alarm responses Safe mode is enabled using the SAF command whose parameter setting 1s stored in the non volatile memory Safe mode uses a modified master slave protocol whereby the pump transmits in response to a received command But the pump also automatically transmits a status packet when an alarm condition occurs Corrupted communications is detected using the 16 bit CCITT CRC algorithm computed over transmitted data Packets transmitted and received include the CRC within the packets The parameter sent with the SAF
62. umping Program This configuration only allows the starting of the Pumping Program This would be useful for example with a laboratory animal trained to press a lever The animal can start the Pumping Program but repeated presses would have no affect until the Pumping Program permits it Pump Motor Operating Pin 7 This output provides an external signal indicating when the pump motor is operating This pin is configured with the ROM n setup command When set to 0 the output is only at logic high when the motor is operating pumping When set to 1 the output 1s logic high when the motor is operating or when the Pumping program is executing a pause timer Otherwise the output is a logic low NE500 series manual 33 Revision 101101 NEXT gt gt ADVANCE www nextadvance com SP500 series OEM Programmable Syringe Pump Pumping Direction Controls Input Pin 3 Output Pin 8 Allows bi directional control of the pumping direction The input pin when activated can be used to change the pumping direction This function therefore is only applicable when the pumping direction change is applicable The function of the input pin is configured with the DIN lt n gt command When the mode is set to reciprocating pumps DIN 0 then if the current pumping direction is withdraw a falling edge sets the direction to infuse If the current pumping direction is infuse a rising edge sets the direction to withdraw Otherwise this input pin ha
63. viding sufficient space for the loaded syringe Then release the white button 3 Lift the syringe holder above the syringe holder block Turn it 1 4 turn and then lower it onto the syringe holder block The syringe holder should be out of the V slot 4 Load the syringe with the barrel over the syringe holder and the syringe plunger towards the middle of the pump Place the barrel on the syringe holder in the V slot with the barrel flange inserted between the syringe holder block and syringe retainer bracket 5 On the pusher block turn the thumbscrew to make the slot large enough for the plunger flange Press in fully the white drive nut button on the pusher block releasing the pusher block Then slide the block towards the syringe plunger Place the syringe plunger flange into the slot and against the anti siphon plate When the flange is positioned in the slot release the white drive nut button 6 Lift the syringe holder to slightly above the height of the syringe barrel and turn the syringe holder 1 4 turn back to its original position and then lower it onto the syringe barrel 7 Firmly push in the syringe retainer bracket against the syringe barrel flange and tighten the 2 thumbscrews on the syringe retainer bracket On the pusher block turn the thumbscrew to tighten the plate against the plunger flange To unload the syringe reverse the instructions for syringe loading NE500 series manual 5 Revision 101101 NEX
64. with many computers can be used to communicate with the pump in the Basic communications mode Next Advance Inc supplies a terminal emulator for demonstration purposes only which allows more complex control of the pump Also this terminal emulator contains a Pump Programming Language PPL which allows Pumping Programs to be developed using symbolic text modified and stored in computer files then downloaded to the pump With a generic terminal emulator setup the terminal emulator with the same baud rate as the pump and with an 8 bit data no parity and 1 stop bit 8N1 data frame Set the communications port to the port that is attached to the pump Also enable local echo half duplex and turn flow control off From the terminal emulator you can interactively control the pump by typing in commands on your computer and seeing the pump s responses on your screen This will give you a feel for how the commands work in addition to allowing you to quickly develop the control sequence that will eventually be coded into the software being developed The final benefit of using a terminal emulator is the elimination of several variables if the control software does not work properly If the pump works correctly with the terminal emulator then this verifies that the hardware is working properly and will work with any software Any communications problems can then be narrowed down to the control software NE500 series manual 31 Revisio

SP500 series Open Housing Programmable Syringe

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