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Agilent 1290 Infinity Valve Drive and Valve Heads

1. Notices Agilent Technologies Inc 2011 2012 No part of this manual may be reproduced in any form or by any means including elec tronic storage and retrieval or translation into a foreign language without prior agree ment and written consent from Agilent Technologies Inc as governed by United States and international copyright laws Manual Part Number G1170 90001 Rev B Edition 05 2012 Printed in Germany Agilent Technologies Hewlett Packard Strasse 8 76337 Waldbronn This product may be used as a com ponent of an in vitro diagnostic sys tem if the system is registered with the appropriate authorities and com plies with the relevant regulations Otherwise it is intended only for gen eral laboratory use Warranty The material contained in this docu ment is provided as is and is sub ject to being changed without notice in future editions Further to the max imum extent permitted by applicable law Agilent disclaims all warranties either express or implied with regard to this manual and any information contained herein including but not limited to the implied warranties of merchantability and fitness for a par ticular purpose Agilent shall not be liable for errors or for incidental or consequential damages in connection with the furnishing use or perfor mance of this document or of any information contained herein Should Agilent and the user have a separate written agreement with
2. Halogenated solvents or mixtures which form radicals and or acids for example 2 CHCls 05 gt 2 COCI 2 HCl This reaction in which stainless steel probably acts as a catalyst occurs quickly with dried chloroform if the drying process removes the stabilizing alcohol Chromatographic grade ethers which can contain peroxides for example THF dioxane di isopropylether such ethers should be filtered through dry aluminium oxide which adsorbs the peroxides Solutions of organic acids acetic acid formic acid and so on in organic solvents For example a 1 solution of acetic acid in methanol will attack steel Solutions containing strong complexing agents for example EDTA ethylene diamine tetra acetic acid Mixtures of carbon tetrachloride with 2 propanol or THF Agilent 1290 Infinity Valve Drive and Valve Heads 53 4 54 Using the Module Solvent information for parts of the 1260 Infinity Bio inert LC system For the Agilent 1260 Infinity Bio inert LC system Agilent Technologies uses highest quality materials see Bio inert Materials on page 21 in the flow path also referred to as wetted parts which are widely accepted by life scientists as they are known for optimum inertness to biological samples and ensure best compatibility to common samples and solvents over a wide pH range Explicitly the complete flow path is free from stainless steel and free from other alloys containing metals such as iro
3. Agilent Module to PC p n Description G1530 60600 RS 232 cable 2 m RS232 61600 RS 232 cable 2 5 m Instrument to PC 9 to 9 pin female This cable has special pin out and is not compatible with connecting printers and plotters It s also called Null Modem Cable with full handshaking where the wiring is made between pins 1 1 2 3 3 2 4 6 5 5 6 4 7 8 8 7 9 9 5181 1561 RS 232 cable 8m Agilent 1290 Infinity Valve Drive and Valve Heads 131 9 Identifying Cables Agilent Module to PC 132 Agilent 1290 Infinity Valve Drive and Valve Heads Agilent 1290 Infinity Valve Drive and Valve Heads 10 Hardware Information Electrical Connections 134 Serial Number Information ALL 134 Front and Rear View of the Module 135 Interfaces 137 Overview Interfaces 139 Config Switch Settings of the Infinity Valve Drive 144 This chapter describes the module in more detail on hardware and electronics RE Agilent Technologies 133 10 Hardware Information Electrical Connections The CAN bus is a serial bus with high speed data transfer The two connectors for the CAN bus are used for internal module data transfer and synchronization The power input socket accepts a line voltage of 100 240 VAC 10 with a line frequency of 50 or 60 Hz Maximum power consumption varies by module There is no voltage selector on your module because the power supply has wide ranging capability There are no externally accessible fuses bec
4. SS Capillary 150 mm x 0 17 mm ns ns 1lg 1xlg p n 5067 4720 Short column to valve 2 SS Capillary 280 mm x 0 17 mm ns ns 1lg 1xlg p n 5067 4722 Long column to valve 2 SS Capillary 120 mm x 0 17 mm ns ns 1xlg 1xlg p n 5067 4719 Valve to valve 1 bypass SS Capillary 200 mm x 0 17 mmmm ns ps 1sh 1xlg p n 5067 4721 Valve to detector 1 TUBING FLEX p n 0890 1713 Valve to waste 2 Column clip set 8 colors p n 5042 9918 1 Agilent 1290 Infinity Valve Drive and Valve Heads 101 8 Parts and Materials Bio inert Capillary Kit 5067 4767 Table 15 Bio inert Capillary kit Description Amount Unit Connection Plastic fittings p n 0100 1259 4 ea TUBING FLEX p n 0890 1713 2 m Column clip set 8 colors p n 5042 9918 1 ea Fingertight fitting long p n 5062 8541 1 ea Fitting holder assembly p n G1316 68706 2 ea PEEK tubing 1 16 p n 0890 1763 1 ea column outlet to valve 2x 300 mm and valve to detector 300 mm PEEK SST capillary bio inert 0 17 mm ID 400 mm long 1 ea Sampler to Valve p n G5667 60500 PEEK SST cap 0 17 mm ID 300 mm long p n G5667 60505 2 ea Valve to column 102 Agilent 1290 Infinity Valve Drive and Valve Heads Parts and Materials 8 Bio inert Capillary Kit 5067 4769 Table 16 Bio inert Capillary Kit Description Amount Unit Connection PEEK tubing 1 16 p n 0890 1763 1 ea From the columns to the valve 4x 300 mm and from valve to detector 300 mm low pressure area
5. 11 Appendix General Safety Information General Safety Information The following general safety precautions must be observed during all phases of operation service and repair of this instrument Failure to comply with these precautions or with specific warnings elsewhere in this manual violates safety standards of design manufacture and intended use of the instrument Agilent Technologies assumes no liability for the customer s failure to comply with these requirements Ensure the proper usage of the equipment The protection provided by the equipment may be impaired The operator of this instrument is advised to use the equipment in a manner as specified in this manual Safety Standards This is a Safety Class I instrument provided with terminal for protective earthing and has been manufactured and tested according to international safety standards Operation 148 Before applying power comply with the installation section Additionally the following must be observed Do not remove instrument covers when operating Before the instrument is switched on all protective earth terminals extension cords auto transformers and devices connected to it must be connected to a protective earth via a ground socket Any interruption of the protective earth grounding will cause a potential shock hazard that could result in serious personal injury Whenever it is likely that the protection has been impaired Agilent 1290 Infini
6. 4 1534 4045 Bearing ring LN N lt QA Y 4 OL E 3 gt N 7 MA NW 2 ls N LDV I je N WO 1 GO EN 1 J CX fe N LL d xD S NNSO NY J xD ve d 4 y NA F o Figure 20 Column Switching Valve Parts 116 Agilent 1290 Infinity Valve Drive and Valve Heads Parts and Materials 8 12 Pos 13 Port Valve Head 210 bar Bio inert yf For bio inert modules use bio inert parts only Linert Item p n Description 5067 4159 Bio inert selector valve 12 position 13 port 210 bar 1 5068 0059 Stator screws 2 5068 0097 Bio inert stator head 3 0101 1288 Bio inert rotor seal and stator face kit 4 1535 4045 Bearing Ring Oty 1 replacement N Figure 21 Column Switching Valve Parts Agilent 1290 Infinity Valve Drive and Valve Heads 117 8 Parts and Materials 12 Pos 13 Port Valve Head 210 bar Bio inert 118 Agilent 1290 Infinity Valve Drive and Valve Heads Agilent 1290 Infinity Valve Drive and Valve Heads 9 Identifying Cables Cable Overview 120 Analog Cables 122 Remote Cables 124 BCD Cables 127 CAN LAN Cables 129 External Contact Cable 130 Agilent Module to PC 131 This chapter provides information on cables used with the Agilent 1200 Infinity Series modules XE Agilent Technologies 119 9 Identifying Cables Cable Overview 120 Never use cables other than the ones supplied by Agilent Technologies to ensure proper functionality and compliance with safety or EMC
7. Array Detectors DAD G1315C D PEEK fused silica Max Light Cartridge Cell Bio inert 10 mm V o 1 0 pl p n G5615 60018 and Max Light Cartridge Cell Bio inert 60 mm V o 4 0 pl p n G5615 60017 for Agilent 1200 Infinity Series Diode Array Detectors DAD G4212A B PEEK fused silica PTFE Bio inert flow cell 8 pL 20 bar pH 1 12 includes Capillary Kit Flow Cells BIO p n G5615 68755 p n G5615 60005 for Agilent 1260 Infinity Fluorescence Detector FLD G1321B Bio inert heat exchanger G5616 60050 for 1290 Infinity PEEK steel cladded Thermostatted Column Compartment G1316C Bio inert Valve heads G4235A G5631A G5639A PEEK ceramic Al 03 based Bio inert Connection capillaries Upstream of sample introduction Titanium Downstream of sample introduction Agilent uses stainless steel cladded PEEK capillaries which keep the flow path free of steel and provide pressure stability to more than 600 bar To ensure optimum bio compatibility of your Agilent 1260 Infinity Bio inert LC system do not include non inert standard modules or parts to the flow path Do not use any parts that are not labeled as Agilent Bio inert For solvent compatibility of these materials see Solvent information for parts of the 1260 Infinity Bio inert LC system on page 54 22 Agilent 1290 Infinity Valve Drive and Valve Heads Introduction to the Agilent 1290 Infinity Valve Drive and Valve Heads 1 Early Maintenance Feedback Main
8. Drive and Valve Heads Suggested actions Please contact your Agilent service representative Please contact your Agilent service representative 69 6 70 Error Information Leak Sensor Open Error ID 0083 The leak sensor in the module has failed open circuit The current through the leak sensor is dependent on temperature A leak is detected when solvent cools the leak sensor causing the leak sensor current to change within defined limits If the current falls outside the lower limit the error message is generated Probable cause Suggested actions 1 Leak sensor not connected to the main Please contact your Agilent service board representative 2 Defective leak sensor Please contact your Agilent service representative 3 Leak sensor incorrectly routed being Please contact your Agilent service pinched by a metal component representative Compensation Sensor Open Error ID 0081 The ambient compensation sensor NTC on the main board in the module has failed open circuit The resistance across the temperature compensation sensor NTC on the main board is dependent on ambient temperature The change in resistance is used by the leak circuit to compensate for ambient temperature changes If the resistance across the sensor increases above the upper limit the error message is generated Probable cause Suggested actions 1 Defective main board Please contact your Agilent service representative Agilent 12
9. Installing the Valve Heads 3 3 When the outer pin is locked into the groove manually screw the nut onto the valve head NOTE Fasten the nut manually Do not use any tools 4 Install all required capillary connections to the valve 5 Push the valve head until it snaps in and stays in the rear position TCC only initialization 6 Power on or power cycle your TCC or Infinity valve drive that the valve head gets recognized during the module Agilent 1290 Infinity Valve Drive and Valve Heads 47 3 48 Installing the Module Installing the Valve Heads Agilent 1290 Infinity Valve Drive and Valve Heads Agilent 1290 Infinity Valve Drive and Valve Heads ee 4 7 e Using the Module e e e d Hints for Successful Use 50 Solvent Information 52 Software Configuration 57 This chapter explains the operational parameters of the module XE Agilent Technologies 49 4 Using the Module Hints for Successful Use The presence of algae in HPLC systems can cause a variety of problems that may be incorrectly diagnosed as instrument or application problems Algae grow in aqueous media preferably in a pH range of 4 8 Their growth is accelerated by buffers for example phosphate or acetate Since algae grow through photosynthesis light will also stimulate their growth Even in distilled water small sized algae grow after some time Instrumental Problems Associated Wit
10. No No G4240A CHIP CUBE 2 Yes No Yes No Yes CAN DC OUT for CAN slaves THERMOSTAT for G1330A B NOT USED The detector DAD MWD FLD VWD RID is the preferred access point for control via LAN The inter module communication is done via CAN 138 Agilent 1290 Infinity Valve Drive and Valve Heads Hardware Information 10 CAN connectors as interface to other modules LAN connector as interface to the control software RS 232C as interface to a computer REMOTE connector as interface to other Agilent products Analog output connector s for signal output Overview Interfaces CAN The CAN is inter module communication interface It is a 2 wire serial bus system supporting high speed data communication and real time requirement LAN The modules have either an interface slot for an LAN card e g Agilent G1369B C LAN Interface or they have an on board LAN interface e g detectors G1315C D DAD and G1365C D MWD This interface allows the control of the module system via a PC with the appropriate control software If an Agilent detector DAD MWD FLD VWD RID is in the system the LAN should be connected to the DAD MWD FLD VWD RID due to higher data load If no Agilent detector is part of the system the LAN interface should be installed in the pump or autosampler RS 232C Serial The RS 232C connector is used to control the module from a computer through RS 232C connection using the appropriate software This conne
11. Rotor seal Vespel 4 1535 4045 Bearing Ring Oty 1 replacement Figure 17 Column Switching Valve Parts 5067 4121 Agilent 1290 Infinity Valve Drive and Valve Heads 113 8 Parts and Materials Valve Head 4 Column Selector 600 bar Bio inert IT For bio inert modules use bio inert parts only Item p n 5067 4134 5068 0059 5068 0044 5068 0093 Aea wo N 5068 0045 5 1535 4045 SS Description Bio inert valve head 4 column selector 600 bar Stator screws Bio inert stator head Stator face assy Bio inert rotor seal PEEK Bearing Ring Oty 1 replacement Figure 18 Column Switching Valve Parts 114 Agilent 1290 Infinity Valve Drive and Valve Heads Parts and Materials Valve Head 6 Column Selector 600 bar Item p n Description 5067 4146 Valve head 6 column selector 600 bar 1 5068 0089 Stator screws 2 5068 0077 Stator Head 3 5068 0076 Rotor seal PEEK 4 1535 4045 Bearing Ring Oty 1 replacement LN N lt QA Y 4 OL E 3 gt N 7 MA NW 2 ls N LDV I je N WO 1 GO EN 1 J CX fe N LL d xD S NNSO NY J xD ve d 4 y NA F n Figure 19 Column Switching Valve Parts Agilent 1290 Infinity Valve Drive and Valve Heads 115 8 Parts and Materials Valve Head 6 Column Selector 1200 bar Item p n Description 5067 4142 Valve head 6 column selector 1200 bar 1 5068 0089 Stator screws 2 5068 0077 Stator Head 3 5068 0067 Rotor seal Vespel
12. Valve Drive and Valve Heads Agilent 1290 Infinity Valve Drive and Valve Heads 7 Maintenance Introduction to Maintenance 76 Cautions and Warnings 77 Overview of Maintenance 79 Cleaning the Module 80 Replacing Parts of the Valve Head 81 Replacing the Fuses of the Infinity Valve Drive 83 Replacing Valve Heads 86 Replacing the Module Firmware 90 This chapter gives you an overview and instructions about the possible maintenance and repair procedures that can be performed by the user RE Agilent Technologies 75 7 Maintenance Introduction to Maintenance 76 The module is designed for easy maintenance The most frequent maintenances such as maintaining valve heads if optional valve drive is installed or replacing low dispersion heat exchangers can be done from the front with module in place in the system stack There are no serviceable parts inside Do not open the module Agilent 1290 Infinity Valve Drive and Valve Heads Maintenance 7 Cautions and Warnings WARNING Toxic flammable and hazardous solvents samples and reagents The handling of solvents samples and reagents can hold health and safety risks gt When working with these substances observe appropriate safety procedures for example by wearing goggles safety gloves and protective clothing as described in the material handling and safety data sheet supplied by the vendor and follow good laboratory practice gt The volume of substance
13. clip 2x re order 4 pk p n 5042 9954 4 ea 106 Agilent 1290 Infinity Valve Drive and Valve Heads Parts and Materials 2 Pos 6 Port Valve Head 600 bar Item p n 5067 4137 i 1535 4857 0101 1417 0101 1409 Aa wo N 1535 4045 Description Valve Head 2 Postion 6 Port 600 bar Stator screws 10 Pk Stator head Rotor Seal PEEK Bearing Ring Qty 1 replacement 4 AD a Figure 11 Column Switching Valve Parts 5067 4137 Agilent 1290 Infinity Valve Drive and Valve Heads 107 8 Parts and Materials 2 Pos 6 Port Ultra High Pressure Valve Head 1200 bar Item p n 5067 4117 1535 4857 5068 0006 5068 0008 Aa wo N 1535 4045 Description 2 pos 6 port ultra high pressure 1200 bar valve head Stator screws Stator head Rotor seal Vespel Bearing Ring Qty 1 replacement Figure 12 Column Switching Valve Parts 5067 4117 108 Agilent 1290 Infinity Valve Drive and Valve Heads Parts and Materials 8 2 Pos 6 Port Valve Head 600 bar Bio inert yf For bio inert modules use bio inert parts only Linert Item p n Description 5067 4148 Bio inert valve head 2 pos 6 port 600 bar 1 5068 0020 Stator Screws 10 pack 2 5068 0060 Bio inert stator head 3 0100 1851 Stator Face 4 0101 1409 Rotor Seal PEEK 5 1535 4045 Bearing Ring Oty 1 replacement Figure 13 Column Switching Valve Parts Agilent 1290 Infinity Valve Drive and Valve Heads 109 8 Parts and Materials 2
14. full handshaking where the wiring is made between pins 1 1 2 3 3 2 4 6 5 5 6 4 7 8 8 7 9 9 5181 1561 RS 232 cable 8 m Agilent 1290 Infinity Valve Drive and Valve Heads 121 9 Identifying Cables Analog Cables EO One end of these cables provides a BNC connector to be connected to Agilent modules The other end depends on the instrument to which connection is being made Agilent Module to 3394 6 Integrators p n 35900 60750 Pin 3394 6 Pin Agilent Signal Name module 1 Not connected 2 Shield Analog 3 Center Analog 122 Agilent 1290 Infinity Valve Drive and Valve Heads Identifying Cables 9 Agilent Module to BNC Connector p n 8120 1840 Pin BNC Pin Agilent Signal Name module Shield Shield Analog Center Center Analog Agilent Module to General Purpose p n 01046 60105 Pin Pin Agilent Signal Name module 1 Not connected 2 Black Analog mu 3 Red Analog Agilent 1290 Infinity Valve Drive and Valve Heads 123 9 Identifying Cables Remote Cables 124 One end of these cables provides a Agilent Technologies APG Analytical Products Group remote connector to be connected to Agilent modules The other end depends on the instrument to be connected to Agilent Module to 3396A Integrators p n 03394 60600 Pin 3396A Pin Agilent Signal Name Active module TTL 9 1 White D
15. installed valve head A failure in this process means either that the movement couldn t be performed properly or it was not noticed correctly by the sensor Probable cause 1 Mechanical problems Friction too high or blockages on the valve drive s motor or on the valve head 2 Defect Sensor on the Valve Drive Motor Suggested actions Check valve head for correct installation Try to identify the source of trouble by installing a different valve head if possible Contact your Agilent Service representative Check valve head for correct installation Try to identify the source of trouble by installing a different valve head if possible Contact your Agilent Service representative Agilent 1290 Infinity Valve Drive and Valve Heads Error Information 6 Initialization of Valve Failed Error ID 24001 The valve drive was not able to operate the valve head correctly Either due to mechanical reasons or the movement couldn t be detected correctly Probable cause Suggested actions 1 Mechanical problems Friction too high or Check valve head for correct installation blockages on the valve drive s motor or on Try to identify the source of trouble by the valve head installing a different valve head if possible Contact your Agilent Service representative 2 Defect Sensor on the Valve Drive Motor Check valve head for correct installation Tryto identify the source of trouble by installing a different valv
16. on Remote control allows easy connection between single instruments or systems to ensure coordinated analysis with simple coupling requirements The subminiature D connector is used The module provides one remote connector which is inputs outputs wired or technique To provide maximum safety within a distributed analysis system one line is dedicated to SHUT DOWN the system s critical parts in case any module detects a serious problem To detect whether all participating modules are switched on or properly powered one line is defined to summarize the POWER ON state of all connected modules Control of analysis is maintained by signal readiness READY for next analysis followed by START of run and optional STOP of run triggered on the respective lines In addition PREPARE and START REQUEST may be issued The signal levels are defined as standard TTL levels 0 V is logic true 5 0 V is false fan out is 10 V input load is 2 2 kOhm against 5 0 V and output are open collector type inputs outputs wired or technique All common TTL circuits operate with a 5 V power supply A TTL signal is defined as low or L when between 0 V and 0 8 V and high or H when between 2 0 V and 5 0 V with respect to the ground terminal Agilent 1290 Infinity Valve Drive and Valve Heads Hardware Information 10 Table 22 Remote Signal Distribution Pin Signal Description 1 DGND Digital ground 2 PREPARE L Request to prepa
17. set up correctly for analysis Exchange the remote cable Check the instrument for defects refer to the instrument s documentation Agilent 1290 Infinity Valve Drive and Valve Heads Lost CAN Partner Error ID 0071 Error Information 6 During an analysis the internal synchronization or communication between one or more of the modules in the system has failed The system processors continually monitor the system configuration If one or more of the modules is no longer recognized as being connected to the system the error message is generated Probable cause 1 CAN cable disconnected 2 Defective CAN cable 3 Defective main board in another module Leak Sensor Short Error ID 0082 Suggested actions Ensure all the CAN cables are connected correctly Ensureall CAN cables are installed correctly Exchange the CAN cable Switch off the system Restart the system and determine which module or modules are not recognized by the system The leak sensor in the module has failed short circuit The current through the leak sensor is dependent on temperature A leak is detected when solvent cools the leak sensor causing the leak sensor current to change within defined limits If the current increases above the upper limit the error message is generated Probable cause 1 Defective leak sensor 2 Leak sensor incorrectly routed being pinched by a metal component Agilent 1290 Infinity Valve
18. these substances observe appropriate safety procedures for example by wearing goggles safety gloves and protective clothing as described in the material handling and safety data sheet supplied by the vendor and follow good laboratory practice 86 Agilent 1290 Infinity Valve Drive and Valve Heads CAUTION Maintenance 7 Valve Damage Using a low pressure valve on the high pressure side can damage the valve gt When using multiple column compartments as part of a method development solution make sure that the high pressure valve head is connected to the autosampler and the low pressure valve head is connected to the detector CAUTION For details please refer to the Agilent 1200 Infinity Series Method Development System System Manual p n G4230 90002 Column Damage or Bias Measurement Results Switching the valve to a wrong position can damage the column or bias measurement results gt Fit the lobe to the groove to make sure the valve is switched to the correct position CAUTION The valve actuator contains sensitive optical parts which need to be protected from dust and other pollutions Pollution of these parts can impair the accurate selection of valve ports and therefore bias measurement results gt Always install a valve head for operation and storage For protecting the actuator a dummy valve head part of Transportation Lock Kit p n G1316 67001 can be used instead of a functional valve Do not t
19. to evaluate if the instrument is in good condition or damaged Notify your Agilent sales and service office about the damage gt An Agilent service representative will inspect the instrument at your site and initiate appropriate actions The Installation of the leak tray and the external leak sensor is optional If you want to attach the leak tray to the valve drive you need to slide the leak tray on to the valve drive before having both clamps attached to the valve drive 1 Ensure the power switch at the rear of the module is OFF 2 Identify the marks for the screws on the side panel of the and the power connector is unplugged cabinet assy and screw the valve rail to the side panel of the cabinet 38 Agilent 1290 Infinity Valve Drive and Valve Heads Installing the Module 3 Installing the Valve Drive 3 Slide the first clamp on to one side of the valve drive 4 Optional Install the leak tray and leak sensor to the valve housing one Agilent 1290 Infinity Valve Drive and Valve Heads 39 3 Installing the Module Installing the Valve Drive proper waste container 7 Attach the waste tubing to the leak plane and guide it to a 8 Connect the power cable to the power connector at the rear of the module u a e a t t a Q e c u Cc 10 Power on the module by switching the Power button at the rear of the module
20. 1 Yes G1311B Quat Pump G1311C Quat Pump VL G1312B Bin Pump G1312C Bin Pump VL 1376A Cap Pump G2226A Nano Pump G5611A Bio inert Quat Pump G4220A B Bin Pump 2 No Yes Yes No Yes G1361A Prep Pump 2 Yes No Yes No Yes CAN DC OUT for CAN slaves Samplers G1329B ALS 2 Yes No Yes No Yes THERMOSTAT for G2260A Prep ALS G1330B G1364B FC PS 2 Yes No Yes No Yes THERMOSTAT for G1364C FC AS G1330B G1364D FC uS CAN DC OUT for CAN G1367E HiP ALS slaves G1377A HiP micro ALS G2258A DL ALS G5664A Bio inert FC AS G5667A Bio inert Autosampler G4226A ALS 2 Yes No Yes No Yes Detectors G1314B VWD VL 2 Yes No Yes 1 Yes G1314C VWD VL Agilent 1290 Infinity Valve Drive and Valve Heads 137 10 Hardware Information Table 20 Agilent 1200 Infinity Series Interfaces Module CAN LAN BCD LAN RS 232 Analog APG Special optional on board Remote G1314E F VWD 2 No Yes Yes 1 Yes G4212A B DAD 2 No Yes Yes 1 Yes G1315C DAD VL 2 No Yes Yes 2 Yes G1365C MWD G1315D DAD VL G1365D MWD VL G1321B FLD 2 Yes No Yes 1 Yes G1362A RID G4280A ELSD No No No Yes Yes Yes EXT Contact AUTOZERO Others G1170A Valve Drive 2 No No No No No Requires a HOST module with on board LAN e g G4212A or G4220A with minimum firmware B 06 40 or C 06 40 or with additional G1369C LAN Card G1316A C TCC 2 No No Yes No Yes G1322A DEG No No No No No Yes AUX G1379B DEG No No No Yes No Yes G4225A DEG No No No Yes No Yes G4227A Flex Cube 2 No No No
21. 2 BCD 7 80 K 3 3 BCD 6 40 4 4 BCD 4 10 5 5 BCDO 1 6 BCD 3 8 z 7 7 BCD 2 4 8 8 BCD 1 2 9 9 Digital ground NC 15 5V Low 128 Agilent 1290 Infinity Valve Drive and Valve Heads Identifying Cables 9 CAN LAN Cables Both ends of this cable provide a modular plug to be connected to Agilent modules CAN or LAN connectors CAN Cables p n Description 5181 1516 CAN cable Agilent module to module 0 5 m 5181 1519 CAN cable Agilent module to module 1 m LAN Cables p n Description 5023 0203 Cross over network cable shielded 3 m for point to point connection 5023 0202 Twisted pair network cable shielded 7 m for point to point connection Agilent 1290 Infinity Valve Drive and Valve Heads 129 9 Identifying Cables External Contact Cable 130 5 10 X045 6 11 One end of this cable provides a 15 pin plug to be connected to Agilent modules interface board The other end is for general purpose Agilent Module Interface Board to general purposes p n G1103 61611 Color Pin Agilent Signal Name module pm White 1 EXT 1 a Brown 2 EXT 1 EE Green 3 EXT2 Yellow 4 EXT 2 Grey 5 EXT 3 Pink 6 EXT 3 Blue 7 EXT 4 Red 8 EXT 4 Black 9 Not connected Violet 10 Not connected Grey pink 11 Not connected Red blue 12 Not connected White green 13 Not connected Brown green 14 Not connected White yellow 15 Not connected Agilent 1290 Infinity Valve Drive and Valve Heads Identifying Cables 9
22. 54 Agilent 1290 Infinity Valve Drive and Valve Heads Contents 6 Agilent 1290 Infinity Valve Drive and Valve Heads Agilent 1290 Infinity Valve Drive and Valve Heads 1 Introduction to the Agilent 1290 Infinity Valve Drive and Valve Heads Overview of the Valve Drive 8 Overview of the Agilent Quick Change Valve Heads 12 Typical Applications 13 Dual and Multi Column Selection 13 Sample Enrichment and Sample Cleanup 15 Alternating Column Regeneration 18 Solvent Selection 20 Bio inert Materials 21 Early Maintenance Feedback 23 This chapter gives an introduction to the module instrument overview and internal connectors RE Agilent Technologies 1 Introduction to the Agilent 1290 Infinity Valve Drive and Valve Heads Overview of the Valve Drive The Agilent 1290 Infinity Valve Drive G1170A is the latest addition to the 1290 Infinity LC system This is a valve drive delivered without a specific valve head To be used in a HPLC system it is required to add a valve head to this device It is compatible with all currently available Agilent Quick Change Valve heads see Table 1 on page 12 It includes the following features Built in power supply Leak handling with a leak pane and a leak sensor underneath the valve head User exchangeable valve heads Agilent Quick Change valve heads Valve type and pressure detected by RF ID tag Flexible mounting bracket for left or right side mounting on LC stacks or at the Agile
23. 67 4744 1 ea Autosampler to Valve SST Capillary 0 8 mm x 0 11 mm500 mm RF M4 p n 5067 4745 1 ea Sampler dual stack to Valve SST Capillary 0 8 mm x 0 11 mm130 mm Ig RF M4 p n 5067 4735 8 ea Valve to heat exchanger and column to valve SST Capillary 0 8 mm x 0 17 mm150 mm lg M4 M4 p n 5067 4737 1 ea Valve to Valve bypass SST Capillary 0 8 mm x 0 11 mm250 mm lg ps M4 p n 5067 4746 1 ea Valve to Detector Wrench 4 mm both ends open end p n 8710 1534 1 ea Flexible PEEK tubing p n 5022 6503 1 ea Valve to Waste PEEK fitting p n G4240 43200 1 ea Heater long up 0 12 mm i d 1 6 pL internal volume p n G1316 80002 2 ea Heater long down 0 12 mm i d 1 6 uL internal volume p n G1316 80003 2 ea Carrier for heat exchanger TCC SL Plus p n G1316 89200 2 ea Fitting holder assembly p n G1316 68706 2 ea Column clip set 8 colors p n 5042 9918 1 ea 1 Fittings RF Removable Fitting connect to Column Heat Exchanger M4 always connect to Valve Ports 100 Agilent 1290 Infinity Valve Drive and Valve Heads Parts and Materials 8 Capillary Kit 5067 4730 Table 14 Capillary Kit PN 5067 4730 Part Number Connection Amount SS Capillary 340 mm x 0 17 mm ps ns 1sh 1xlg p n 5067 4723 Autosampler to valve 1 SST Capillary 700 x 0 17 mm ps ps 1sh 1xlg p n 5067 4648 Pump to valve ACR 1 only SS Capillary 90 mm x 0 17 mm ns ns 1sh 1xlg p n 5067 4724 Valve to heat 4 exchanger and heat exchanger to column
24. 90 Infinity Valve Drive and Valve Heads Error Information 6 Compensation Sensor Short Error ID 0080 The ambient compensation sensor NTC on the main board in the module has failed short circuit The resistance across the temperature compensation sensor NTC on the main board is dependent on ambient temperature The change in resistance is used by the leak circuit to compensate for ambient temperature changes If the resistance across the sensor falls below the lower limit the error message is generated Probable cause Suggested actions 1 Defective main board Please contact your Agilent service representative Leak Error ID 0064 A leak was detected in the module The signals from the two temperature sensors leak sensor and board mounted temperature compensation sensor are used by the leak algorithm to determine whether a leak is present When a leak occurs the leak sensor is cooled by the solvent This changes the resistance of the leak sensor which is sensed by the leak sensor circuit on the main board Probable cause Suggested actions 1 Loose fittings Ensure all fittings are tight 2 Broken capillary Exchange defective capillaries Agilent 1290 Infinity Valve Drive and Valve Heads 71 6 Error Information Module Specific Error Messages 72 Initialization of Valve Failed Error ID 24000 During the initialization process the motor of the valve drive moves to some special positions depending on the
25. EEK capillaries are very sensitive to high pressure especially under such conditions Agilent uses stainless steel cladded PEEK capillaries to keep the flow path free of steel and to ensure pressure stability to at least 600 bar If in doubt consult the available literature about the chemical compatibility of PEEK Agilent 1290 Infinity Valve Drive and Valve Heads Using the Module 4 Titanium Titanium is highly resistant to oxidizing acids for example nitric perchloric and hypochlorous acid over a wide range of concentrations and temperatures This is due to a thin oxide layer on the surface which is stabilized by oxidizing compounds Reducing acids for example hydrochloric sulfuric and phosphoric acid can cause slight corrosion which increases with acid concentration and temperature For example the corrosion rate with 3 HCl about pH 0 1 at room temperature is about 13 um year At room temperature titanium is resistant to concentrations of about 5 sulfuric acid about pH 0 3 The addition of nitric acid to hydrochloric or sulfuric acids significantly reduces corrosion rates Titanium is subject to corrosion in anhydrous methanol which can be avoided by adding a small amount of water about 3 Slight corrosion is possible with ammonia gt 10 Fused silica Fused silica is inert against all common solvents and acids except hydrofluoric acid It is corroded by strong bases and should not be used above pH 12 at room te
26. Heads Installing the Module 3 The tag reader reads the valve head properties from the valve head RFID tag during initialization of the module Valve properties will not be updated if the valve head is replaced while the module is on Selection of valve port positions can fail if the instrument does not know the properties of the installed valve To have the valve correctly recognized by the Agilent Infinity valve drive you must have the valve drive powered off for at least 10 s Agilent 1290 Infinity Valve Drive and Valve Heads 45 3 Installing the Module Installing the Va 1 The two different pins blue amp green on the valve shaft must fit into the corresponding grooves of the actuator axis The outside pin red must fit into the outside groove 2 a Itcan be possible that you have to turn the valve head until the outside pin completely locks in While turning the valve you should feel some resistance from the drive Otherwise the pins on the valve shaft are not properly fitted into the corresponding adapters on the valve drive b Itcan be possible that you have to turn the valve head until the outside pin completely locks in While turning the valve you should feel some resistance from the drive Otherwise the pins on the valve shaft are not properly fitted into the corresponding adapters on the valve drive 46 Agilent 1290 Infinity Valve Drive and Valve Heads Installing the Module
27. N Pressure Positions Ports Typical Application bar G4230A 600 8 9 Method development solution kits G4230B 1200 8 9 G4231A 600 2 6 Any two way switching e g between two detectors between G4231B 1200 2 6 G4232A micro 600 G4232B 1200 G4234A 600 G4234B 1200 G4235A 210 G5631A 600 G5639A 600 waste and detector between two columns for G4231B 1200 2 6 matrix stripping for pre concentration 2 10 Anything a 2pos 6port valve can do plus alternating column 2 10 regeneration The G4232A can be used for standard as well as cap nano applications uses M4 fittings 6 14 4 to 6 column selection 6 14 12 13 Solvent selection or fractionation 2 6 Same as G4231A B 4 10 4 column selection Agilent 1290 Infinity Valve Drive and Valve Heads Introduction to the Agilent 1290 Infinity Valve Drive and Valve Heads 1 Typical Applications The Infinity valve heads allow the user a variety of different applications They can either be installed to a Infinity valve drive or to a G1316C TCC that is equipped with an internal valve actuator Examples of typical applications are Dual and multiple column selection Sample enrichment and sample cleanup Alternating Column Regeneration Solvent selection Dual and Multi Column Selection Dual column selection 2pos 6port valve p n G4231A B and 2pos 10port valve p n G4232A B Advantages Increase productivity Higher instrument up time Quickly change between two dif
28. Names that is used for the method report and the instrument actuals The Position Description is limited to 19 characters Time Table The Time Table can be used to edit and run a valve program during a sequence of sample runs The Time Table contains 3 columns Line Time and Position The Time Table is limited to 20 lines The number of selection in the Position column depends on the valve that has been configured Position X Next Position Insert Append Cut Copy Paste Switches the valve to the selected position Switches to the next available position If the valve is on the highest position it will switch to position 1 Inserts a line in the Time Table above the selected position Appends a line at the end of the Time Table Cuts the selected line s out of the Time Table and saves it to the clipboard Copies the selected line s from the table to the clipboard Pastes line s from the Clipboard to the Time Table Agilent 1290 Infinity Valve Drive and Valve Heads Agilent 1290 Infinity Valve Drive and Valve Heads 0905 5 Troubleshooting and Diagnostics o o E e e i e 7 Overview of the Module s Indicators and Test Functions 62 e Module Status Indicator 63 Agilent Lab Advisor Software 64 This chapter gives an overview about the troubleshooting and diagnostic features and the different user interfaces RE Agilent Technologies 61 5 Troubleshooting and Diagnostics Overview of the Mod
29. PEEK SST capillary bio inert 0 17 mm ID 400 mm long 1 ea Sampler to valve p n G5667 60500 PEEK SST cap 0 17 mm ID 300 mm long p n G5667 60505 4 ea Valve to column Column clip set 8 colors p n 5042 9918 1 ea Fingertight fitting long p n 5062 8541 1 ea Fitting holder assembly p n G1316 68706 2 ea Agilent 1290 Infinity Valve Drive and Valve Heads 103 Parts and Materials Capillary Kit 5067 4800 Table 17 Capillary Kit 5067 4800 Connection Description Amount Unit SST Capillary 0 8 mm x 0 11 mm340 mm RF M4 p n 5067 4744 1 ea SST Cap 0 17 mm ID 700 mm SW 1 16 M4 p n 5067 5120 1 ea SST Capillary 90x0 11 mm SW 1 16 M4 p n 5067 5106 2 ea SST Capillary 0 8x0 11 mm150 mm Ig RF M4 p n 5067 5104 2 ea SST Capillary 0 8x0 11 mm280 mm Ig RF M4 p n 5067 5107 1 ea SST Capillary 0 8 mm x 0 17 mm150 mm Ig M4 M4 p n 5067 4737 1 ea SST Capillary 0 8 mm x 0 11 mm250 mm lg ps M4 p n 5067 4746 1 ea Flexible PEEK tubing p n 5022 6503 2 ea PEEK fitting p n G4240 43200 2 ea Column clip set 8 colors p n 5042 9918 1 ea Fitting holder assembly p n G1316 68706 2 ea Heater long up 0 12 mm i d 1 6 pL internal volume p n G1316 80002 1 ea Heater long down 0 12 mm i d 1 6 uL internal volume p n G1316 80003 1 ea Carrier for heat exchanger TCC SL Plus p n G1316 89200 2 ea Autosampler to valve Pump to valve ACR only Valve to heat exchanger Short column to valve Long column to valve Valve to valve
30. Pos 10 Port Micro Valve Head 600 bar Item p n 5067 4144 i 5068 0054 0101 1421 0101 1415 Aa wo N 1535 4045 Description Micro Valve Head 2 Position 10 Port 600 bar Stator screws 10 Pk Stator Head Rotor Seal PEEK Bearing Ring Qty 1 replacement Figure 14 Column Switching Valve Parts 5067 4144 110 Agilent 1290 Infinity Valve Drive and Valve Heads Parts and Materials 8 2 Pos 10 Port Ultra High Pressure Valve Head 1200 bar Item p n Description 5067 4118 2 pos 10 port ultra high pressure 1200 bar valve head 1 5068 0019 Stator screws 2 5068 0011 Stator head 3 5068 0012 Rotor seal Vespel 4 1535 4045 Bearing Ring Oty 1 replacement 0 BY e OC ut S amp K e Figure 15 Column Switching Valve Parts 5067 4118 Agilent 1290 Infinity Valve Drive and Valve Heads 111 8 Parts and Materials 8 Pos 9 Port Valve Head 600 bar Item p n 5067 4107 1535 4857 5068 0001 5067 4111 Aa wo N 1535 4045 Description Valve Head 8 Position 9 Port 600 bar Stator screws Stator head Rotor Seal PEEK Bearing Ring Oty 1 replacement Figure 16 Column Switching Valve Parts 5067 4107 112 Agilent 1290 Infinity Valve Drive and Valve Heads Parts and Materials 8 8 Pos 9 Port Ultra High Pressure Valve Head 1200 bar Item p n Description 5067 4121 8 pos 9 port valve head high pressure 1200 bar 1 1535 4857 Stator screws 2 5068 0001 Stator head 3 5068 0002
31. are 64 dimensions 29 E electrical connections description of 134 electronic waste 151 EMF early maintenance feedback 23 error message position cluster partner missing 74 pressure cluster partner missing 74 valve tag violation 73 error messages initialization of valve failed 72 lost CAN partner 69 remote timeout 68 error messages Agilent 1290 Infinity Valve Drive and Valve Heads Index compensation sensor open 70 compensation sensor short 71 leak sensor open 70 leak sensor short 69 leak 71 shutdown 68 timeout 67 valve switching failed 73 external contact cable 130 F firmware 90 frequency range 29 G general error messages 6 7 H humidity 29 installation bench space 28 site requirements 25 interfaces 137 internet 154 L LAN cable 129 leak sensor open 70 leak sensor short 69 155 Index leak 71 line frequency 29 line voltage 29 lost CAN partner 69 M maintenance feedback 23 materials bio inert 21 message initialization of valve failed 72 position cluster partner missing 74 pressure cluster partner missing 74 remote timeout 68 valve switching failed 73 valve tag violation 73 method settings 59 non operating altitude 29 non operating temperature 29 0 operating Altitude 29 operating temperature 29 P packaging damaged 34 parts accessory kit 96 parts identification cables 119 parts damaged 35 missing 35 physical specifications 29 power consump
32. aste After the valve switch a second pump backflushes the analytes out of the pre column onto the separation column This allows injection of large volumes onto the pre column significantly expanding sensitivity in the range of ten to several thousands Stripping methods Stripping methods handle analytes and matrices in the opposite way to enrichment methods Matrix components are retained on the pre column while the analytes pass through to the separation column After the valve switches an additional pump backflushes the matrix components out of the pre column to waste while the analytes are separated on the main column Backflushing prepares the pre column for the next injection Alternating Column Regeneration Only 2pos 10port valve p n G4232A B Advantages High sample throughput Increased productivity High efficiency Alternating column regeneration is a convenient way to increase the sample throughput The Agilent 1200 Infinity Series 2 position 10 port valves can be used to increase the efficiency in laboratories running large amounts of samples Gradient elution is a common technique for separation of complex samples in liquid chromatography which requires column regeneration before the subsequent run is started Using alternating column regeneration valuable time for the analysis is saved Core of the alternating column regeneration is the Agilent 1200 Infinity Series 2 position 10 port valves which allows simu
33. ause automatic electronic fuses are implemented in the power supply Never use cables other than the ones supplied by Agilent Technologies to ensure proper functionality and compliance with safety or EMC regulations Serial Number Information ALL The serial number information on the instrument labels provide the following information CCYWWSSSSS Format CC country of manufacturing DE Germany JP Japan CN China YWW year and week of last major manufacturing change e g 820 could be week 20 of 1998 or 2008 SSSSS real serial number 134 Agilent 1290 Infinity Valve Drive and Valve Heads Hardware Information 10 Electrical Connections Front and Rear View of the Module Status lamp Sey Ailem Te 1200 Infinity Valve Drivs Serial number label Figure 22 Front View of 1290 Infinity Valve Drive Agilent 1290 Infinity Valve Drive and Valve Heads 135 10 Hardware Information Electrical Connections External leak sensor connector Config switch CAN ports Power switch Power connector Figure 23 Rear View of 1290 Infinity Valve Drive 136 Agilent 1290 Infinity Valve Drive and Valve Heads Hardware Information 10 Interfaces The Agilent 1200 Infinity Series modules provide the following interfaces Table 20 Agilent 1200 Infinity Series Interfaces Module CAN LAN BCD LAN RS 232 Analog APG Special optional on board Remote Pumps G1310B Iso Pump 2 Yes No Yes
34. ber counter Table5 Specifications Agilent Quick Change Valve Heads Kit PN Valve PN Description max Pressure Fittings Port Port Liquid pH Range bar Volume Contact G4230A B 5067 4107 8 pos 9 port high pressure 600 10 32 0 55 uL PEEK SST 9 44 valve head G4230B 5067 4121 8 pos 9 port UHP valve 1200 10 32 0 55 pL Vespel 0 102 head SST G4231A 5067 4137 2 pos 6 port valve head 600 10 32 0 51 uL PEEK SST 9 14 G4231B 5067 4117 2 pos 6 port valve head 1200 10 32 0 51 uL Vespel 0 102 SST G4232A 5067 4144 2 pos 10 port micro valve 600 M4 89 0 nL PEEK SST 9 14 head G4232B 5067 4118 2 pos 10 port UHP valve 1200 10 32 0 22 uL Vespel 0 102 head SST G4234A 5067 4146 6 pos 14 port valve head for 600 M4 special PEEK SST 9 14 column selection G4234B 5067 4142 6 pos 14 port UHP valve 1200 M4 special Vespel 0 10 head for column selection SST 30 Agilent 1290 Infinity Valve Drive and Valve Heads Site Requirements and Specifications 2 Table5 Specifications Agilent Quick Change Valve Heads Kit PN Valve PN Description max Pressure Fittings Port Port Liquid pH Range bar Volume Contact G4235A 5067 4159 12 pos 13 port selection 210 10 32 16 4 pL PEEK 0 14 valve head bio inert Ceramic G5631A 5067 4148 2 pos 6 port valve head 600 10 32 1 71 uL PEEK 0 14 bio inert Ceramic G5639A 5067 4134 4 pos 10 port valve head for 600 10 32 special PEEK 0 14 column selection bio inert Ceramic incompatible with s
35. bypass Valve to detector Valve to waste 104 Agilent 1290 Infinity Valve Drive and Valve Heads Capillary Kit 5067 5103 Table 18 Capillary Kit 5067 5103 Parts and Materials Description Amount Unit Connection SST Capillary 340x0 17 mm ps ns SW M4 p n 5067 5108 1 ea Autosampler to valve SST Cap 0 17 mm ID 700 mm SW 1 16 M4 p n 5067 5120 1 ea Pump to valve ACR only SST Capillary 90x0 17 mm SW 1 16 M4 p n 5067 5109 2 ea Valve to heat exchanger SST Capillary 90x0 17 mm RF M4 p n 5067 5110 2 ea Heat exchanger to column SST Capillary 0 8x0 17 mm150 mm Ig RF M4 p n 5067 5111 2 ea Short column to valve SST Capillary 0 8x0 17 mm280 mm lg RF M4 p n 5067 5112 2 ea Long column to valve SST Capillary 0 8 mm x 0 17 mm150 mm Ig M4 M4 p n 5067 4737 1 ea Valve to valve bypass SST Capillary 0 8x0 17 mm250 mm lg ps M4 p n 5067 5113 1 ea Valve to detector Flexible PEEK tubing p n 5022 6503 2 ea Valve to waste PEEK fitting p n G4240 43200 2 ea Column clip set 8 colors p n 5042 9918 ea Agilent 1290 Infinity Valve Drive and Valve Heads 105 8 Parts and Materials Tubing Kit Table 19 Tubing Kit Description Amount Unit Connection Solvent tubing 5m p n 5062 2483 2 ea Adapter PEEK int 1 4 28 to ext 10 32 p n 0100 2298 5 ea Bottle head assembly p n G1311 60003 4 ea Tefzel ferrules and SSL lock rings 1 8 inch 10 pck p n 5063 6598 1 pk PPS nuts 1 8 inch 10 pck p n 5063 6599 1 pk Tubing
36. c Most data available refers to room temperature typically 20 25 C 68 77 F If corrosion is possible it usually increases at higher temperatures If in doubt consult additional resources Agilent 1290 Infinity Valve Drive and Valve Heads Using the Module 4 Software Configuration Configuring the Valves in the Software Iritremert Comfqurater intent a Contepe tte Modes Sebectet Modules EE Ape eo rud te Wa Congue ven 5n i Jw Eca g Compact LE GST oom ccam J tot tr corfigurgton change st Chem Station sarte ze Lancet et 1 Configure your instrument by choosing between available modules 2 Choose your valve drive s from the list of Configurable modules auto or manual configuration A valve head needs to be detected from the module before you can configure it in the software Please refer to the Installation of the valve heads chapter for details Agilent 1290 Infinity Valve Drive and Valve Heads 57 4 58 Using the Module Assign a Pressure Limit Cluster to the Valve Control Cancel The valve head s RFID Tag holds the information about its max pressure An assigned pressure cluster partner assures that this limit gets not exceeded The max pressure information of the valve head will become the new maximum pressure setting of the assigned pressure cluster partner This helps to avoid damage to the valve head if the max pressur
37. capabilities for all Agilent 1200 Infinity Series modules This includes diagnostic capabilities calibration procedures and maintenance routines for all the maintenance routines The Agilent Lab Advisor software also allows users to monitor the status of their LC instruments The Early Maintenance Feedback EMF feature helps to carry out preventive maintenance In addition users can generate a status report for each individual LC instrument The tests and diagnostic features as provided by the Agilent Lab Advisor software may differ from the descriptions in this manual For details refer to the Agilent Lab Advisor software help files The Instrument Utilities is a basic version of the Lab Advisor with limited functionality required for installation use and maintenance No advanced repair troubleshooting and monitoring functionality is included Agilent 1290 Infinity Valve Drive and Valve Heads Agilent 1290 Infinity Valve Drive and Valve Heads eec 6 Error Information What Are Error Messages 66 General Error Messages 67 Timeout 67 Shutdown 68 Remote Timeout 68 Lost CAN Partner 69 Leak Sensor Short 69 Leak Sensor Open 70 Compensation Sensor Open 70 Compensation Sensor Short 71 Leak 71 Module Specific Error Messages 72 Initialization of Valve Failed 72 Initialization of Valve Failed 73 Valve Tag Violation 73 Pressure Cluster Partner Missing 74 Position Cluster Partner Missing 74 This chapter describes the meaning of error
38. ctor can be configured with the configuration switch module at the rear of the module Refer to Communication Settings for RS 232C Agilent 1290 Infinity Valve Drive and Valve Heads 139 10 Hardware Information There is no configuration possible on main boards with on board LAN These are pre configured for 19200 baud 8 data bit with no parity and one start bit and one stop bit are always used not selectable The RS 232C is designed as DCE data communication equipment with a 9 pin male SUB D type connector The pins are defined as Table 21 RS 232C Connection Table Pin Direction Function 1 In DCD 2 In RxD 3 Out TxD 4 Out DTR 5 Ground 6 In DSR 7 Out RTS 8 In CTS 9 In RI 140 Agilent 1290 Infinity Valve Drive and Valve Heads Hardware Information 10 Instrument PC DCD 1 1 DCD RX 2 au 2 RX TX 3 X 3 Tx DTR 4 a xe DTR GND 5 Y 5 GND DSR 6 6 DSR RTS 7 X 7 RTS CTS 8 8 CTS RI 9 9 RI DB9 DB9 DB9 DB9 Male Female Female Male Figure 24 RS 232 Cable Analog Signal Output The analog signal output can be distributed to a recording device For details refer to the description of the module s main board Agilent 1290 Infinity Valve Drive and Valve Heads 141 10 Hardware Information 142 APG Remote The APG Remote connector may be used in combination with other analytical instruments from Agilent Technologies if you want to use features as common shut down prepare and so
39. ctronic Equipment Directive Abstract The Waste Electrical and Electronic Equipment WEEE Directive 2002 96 EC adopted by EU Commission on 13 February 2003 is introducing producer responsibility on all electric and electronic appliances starting with 13 August 2005 This product complies with the WEEE Directive 2002 96 EC marking requirements The affixed label indicates that you must not discard this electrical electronic product in domestic household waste Product Category With reference to the equipment types in the WEEE Directive Annex I this product is classed as a Monitoring and Control Instrumentation product Do not dispose off in domestic household waste To return unwanted products contact your local Agilent office or see www agilent com for more information Agilent 1290 Infinity Valve Drive and Valve Heads 151 11 Appendix Radio Interference Cables supplied by Agilent Technologies are screened to provide optimized protection against radio interference All cables are in compliance with safety or EMC regulations Test and Measurement If test and measurement equipment is operated with unscreened cables or used for measurements on open set ups the user has to assure that under operating conditions the radio interference limits are still met within the premises 152 Agilent 1290 Infinity Valve Drive and Valve Heads Appendix 11 Sound Emission Manufacturer s Declaration This statement is provid
40. d with Accessory Kit p n G1170 68705 see Accessory Kit on page 96 Agilent 1290 Infinity Valve Drive and Valve Heads 35 3 Installing the Module Installing the Valve Drive Installing the Valve Drive The 1290 Infinity Valve Drive can be installed in different ways It can be attached to either side of your Instrument with the use of the Valve Rail 1260 and 1290 Series Pumps and Detectors for older modules order new cover kits or it can be mounted to a G1383A column organizer by using the optional column stand mount 36 Agilent 1290 Infinity Valve Drive and Valve Heads Installing the Module 3 netalling the Installi g e Ve Assembling and Installing the Leak Tray and Leak Sensor correctly j Only connect or disconnect the leak sensor while the valve drive is powered off The valve drive must be powered off for at least 10 s to recognize any hardware changes 1 Attach the leak tray clamp to the leak tray 2 Push the leak sensor into its holder Q E 3 Slide the leak tray onto the bottom of the valve drive 4 Connectthe leak sensor cable to the valve drive Agilent 1290 Infinity Valve Drive and Valve Heads 37 3 Installing the Module Mounting the Valve to an Instrument by Using a Valve Rail CAUTION Defective on arrival problems If there are signs of damage please do not attempt to install the module Inspection by Agilent is required
41. e 43 The valve heads can be installed by mounting the valve heads onto the valve drives and fastening the nut manually do not use any tools Be sure that the guide pin snaps into the groove of the valve drive thread The valves are mounted on pull out rails to allow easy installation of capillaries Push the valve gently into its housing until it snaps into the inner position push it again and it slides out If all capillaries are installed push the valve back into its housing see Installing the Valve Head and Connecting Capillaries on page 44 Agilent 1290 Infinity Valve Drive and Valve Heads Installing the Module 3 Removing the Transportation Lock and the Valve Dummy The following procedure demonstrates the necessary steps for installing the valve head to the valve drive of a TCC For the installation of a valve head to a G1170A Infinity Valve Drive you can ignore the steps that describe the TCC features of the transportation lock and spring loaded valve drive 1 When unscrewing the transportation lock TCC only 2 To remove the valve dummy loosen the nut manually push it back until the last screw is removed the valve rail f is spring loaded Agilent 1290 Infinity Valve Drive and Valve Heads 43 3 Installing the Module Installing the Valve Head and Connecting Capillaries BIO CAUTION For bio inert modules use bio inert parts only The valve actuator contains sensitive optical parts which
42. e flow path Agilent 1290 Infinity Valve Drive and Valve Heads 51 4 Using the Module Solvent Information Observe the following recommendations on the use of solvents Follow recommendations for avoiding the growth of algae see pump manuals Small particles can permanently block capillaries and valves Therefore always filter solvents through 0 4 um filters Avoid or minimize the use of solvents that may corrode parts in the flow path Consider specifications for the pH range given for different materials like flow cells valve materials etc and recommendations in subsequent sections 52 Agilent 1290 Infinity Valve Drive and Valve Heads Using the Module 4 Solvent compatibility for stainless steel in standard LC systems Stainless steel is inert against many common solvents It is stable in the presence of acids and bases in the pH range specified for standard HPLC pH 1 12 5 It can be corroded by acids below pH 2 3 In general following solvents may cause corrosion and should be avoided with stainless steel Solutions of alkali halides their respective acids for example lithium iodide potassium chloride and so on and aequous solutions of halogenes High concentrations of inorganic acids like nitric acid sulfuric acid and organic solvents especially at higher temperatures replace if your chromatography method allows by phosphoric acid or phosphate buffer which are less corrosive against stainless steel
43. e head if possible Contact your Agilent Service representative Valve Tag Violation Error ID 24006 The valve drive identified a different valve head than it had identified during the last initialization Probable cause Suggested actions 1 Avalve head has been exchanged For changing the valve head follow the hot plugged while the valve drive was still instructions Replacing Valve Heads on powered on page 86 It is important to have the valve switched off for at least 10 s after or before a new valve head has been installed Soft power down power supply of the valve drive Whenever you want to power cycle the valve drive for a re boot it needs to be powered off for at least 10 seconds Agilent 1290 Infinity Valve Drive and Valve Heads 73 6 74 Error Information Pressure Cluster Partner Missing The connection from the valve drive to a defined pressure cluster partner is lost Probable cause Suggested actions 1 Communication issues Check the CAN cable connections of the modules 2 Configuration mismatch Check and correct if necessary the valve configuration and presence of defined pressure cluster partner Position Cluster Partner Missing Probable cause Suggested actions 1 Communication issues Check the CAN cable connections of the modules 2 Configuration mismatch Check and correct if necessary the valve configuration and presence of defined position cluster partner Agilent 1290 Infinity
44. e of the pump is higher then the valve head s maximum pressure 1 Open the valve s control menu right click on the valve s GUI or via the Instrument Tab 2 Assign the valve s pressure partner also None or several partners possible Assigning a Pressure Limit Cluster only works in combination with a 1290 Series Infinity Binary Pump G4220A B Agilent 1290 Infinity Valve Drive and Valve Heads Using the Module 4 Software Configuration Possible Method Settings for the Valve Figure 9 Method settings of the Valve After the Agilent 1290 Series Valves have been installed and configured the valve parameters can be edited in the software Choose Method by right clicking on the the valve s GUI icon or via Edit entire method under the menu to open the valve dialog box as displayed Figure 9 on page 59 Position When loading a method the valve is switched to the position that is displayed in the Position dropdown box If you select Use Current the valve remains in the current position when a new method is loaded If you select a new position in the dropdown box and click OK the Setup Valve dialog box will be closed and the valve switches to the new position Agilent 1290 Infinity Valve Drive and Valve Heads 59 4 60 Using the Module Position switch at end of run Gives you the possibility to define a position the valve is switched to at the end of the run Position Names Define the Position
45. eak plane Spanner nut Fuse 2 AT250 V Valve rail assembly See Installing the Valve Drive on page 36 Rail assy for column organizer See Installing the Valve Drive on page 36 Agilent 1290 Infinity Valve Drive and Valve Heads Parts and Materials 8 Valve Drive Parts Figure 10 Valve Drive Parts Agilent 1290 Infinity Valve Drive and Valve Heads 93 8 Parts and Materials Valve Options Overview This overview gives a summary of the main parts and assemblies More details are available with each valve option in this chapter Table9 Agilent Quick Change Valve Heads Kit description Valve head Rotor seal Stator heads Method development Valve Head 8 Rotor Seal PEEK p n Stator head p n valves kit p n 64230A 2 Method development valves kit p n G4230B 2pos 6port valve p n G4231B 2pos 6port valve p n G4231A 2pos 10port valve p n G4232B 2pos 10port valve p n G4232A Position 9 Port 600 bar p n 5067 4107 8 pos 9 port valve head high pressure 1200 bar p n 5067 4121 2 pos 6 port ultra high pressure 1200 bar valve head p n 5067 4117 Valve Head 2 Postion 6 Port 600 bar p n 5067 4137 2 pos 10 port ultra high pressure 1200 bar valve head p n 5067 4118 Micro Valve Head 2 Position 10 Port 600 bar p n 5067 4144 5067 4111 Rotor seal Vespel p n 5068 0002 Rotor seal Vespel p n 5068 0008 Rotor Seal PEEK p n 0101 1409 Rotor seal Ve
46. ed to comply with the requirements of the German Sound Emission Directive of 18 January 1991 This product has a sound pressure emission at the operator position lt 70 dB Sound Pressure Lp lt 70 dB A At Operator Position Normal Operation e According to ISO 7779 1988 EN 27779 1991 Type Test Agilent 1290 Infinity Valve Drive and Valve Heads 153 11 Appendix Agilent Technologies on Internet For the latest information on products and services visit our worldwide web site on the Internet at http www agilent com Select Products Chemical Analysis It will provide also the latest firmware of the modules for download 154 Agilent 1290 Infinity Valve Drive and Valve Heads Index A accessory kit 96 accuracy of wavelength 30 Agilent Diagnostic software 64 Agilent Lab Advisor software 64 Agilent Lab Advisor 64 Agilent oninternet 154 ambient non operating temperature 29 ambient operating temperature 29 analog signal 141 analog cable 122 apgremote 142 BCD cable 127 bench space 28 bio inert 44 78 materials 21 C cable analog 122 BCD 127 CAN 129 external contact 130 LAN 129 remote 124 RS 232 131 cables analog 120 BCD 120 CAN 121 external contact 121 LAN 121 overview 120 remote 120 RS 232 121 CAN cable 129 cleaning 80 column organizer 41 compensation sensor open 70 compensation sensor short 71 condensation 28 D defect on arrival 34 delivery checklist 35 Diagnostic softw
47. ent 1290 Infinity Valve Drive and Valve Heads Hardware Information 10 Special Settings Boot Resident Firmware update procedures may require this mode in case of firmware loading errors main firmware part If you use the following switch settings and power the instrument up again the instrument firmware stays in the resident mode It is not operable as a module It only uses basic functions of the operating system for example for communication In this mode the main firmware can be loaded using update utilities Forced Cold Start A forced cold start can be used to bring the module into a defined mode with default parameter settings CAUTION Loss of data Forced cold start erases all methods and data stored in the non volatile memory Exceptions are calibration settings diagnosis and repair log books which will not be erased gt Save your methods and data before executing a forced cold start Agilent 1290 Infinity Valve Drive and Valve Heads 145 10 Hardware Information Config Switch Settings of the Infinity Valve Drive 146 Agilent 1290 Infinity Valve Drive and Valve Heads Agilent 1290 Infinity Valve Drive and Valve Heads 11 Appendix General Safety Information 148 The Waste Electrical and Electronic Equipment Directive 151 Radio Interference 152 Sound Emission 153 Agilent Technologies on Internet 154 This chapter provides addition information on safety legal and web E Agilent Technologies 147
48. equired For details about the needed parts and orientation please refer to Parts and Materials on page 91 Disassembling and reassembling the valve head For bio inert modules use bio inert parts only Stator head Scratches and damages on the inner surface blockages Stator face assy When visibly scratched or when the valve performance shows indication of leakage or wear Rotor seal assy After approximately 10000 to 20000 injections or when the valve performance shows indication of leakage or wear Description Hex key Toxic flammable and hazardous solvents samples and reagents The handling of solvents samples and reagents can hold health and safety risks Be sure that no solvent can drop out of the solvent connections when removing them from your valve head When working with these substances observe appropriate safety procedures for example by wearing goggles safety gloves and protective clothing as described in the material handling and safety data sheet supplied by the vendor and follow good laboratory practice Agilent 1290 Infinity Valve Drive and Valve Heads 81 7 82 Maintenance 1 Use the Hex Key to open and remove the Stator Screws from the Stator Head 2 Carefully disassemble the necessary Valve Head parts to gain access to the one you want to replace While doing so please observe the orientation of the parts 3 Independent of the part you want to replace always inspect all parts for s
49. ferent stationary phases to check your separation selectivity or use two identical stationary phases to have the second column immediately available after the first one loses efficiency for example with complex matrices Agilent 1290 Infinity Valve Drive and Valve Heads 13 1 Introduction to the Agilent 1290 Infinity Valve Drive and Valve Heads Typical Applications Multi Column Selection With the 6 position selection valve G4234A B and the capillary kit for Column Selection you can set up your system for use with up to 6 columns as displayed in Figure 3 on page 14 Or you can use the system with 5 columns and one flow path for flow injection analysis or for flushing the system This setup allows you to switch between these columns for faster method development or method validation The multi column setup might also be used if several operators are sharing system Column 2 Column 3 Column 4 Column 5 Column 6 Auto sampler Figure 3 Multiple Column Selection Example of Schematic Setup for 6 Column Selector 14 Agilent 1290 Infinity Valve Drive and Valve Heads Introduction to the Agilent 1290 Infinity Valve Drive and Valve Heads 1 Sample Enrichment and Sample Cleanup 2pos 6port valve p n G4231A B and 2pos 10port valve p n G4232A B Advantages Easy automation of sample preparation Higher reproducibility Increased productivity and sensitivity Sample cleanup is essential for samples with co
50. ferred to as wetted parts which are widely accepted by life scientists as they are known for optimum inertness to biological samples and ensure best compatibility with common samples and solvents over a wide pH range Explicitly the complete flow path is free of stainless steel and free of other alloys containing metals such as iron nickel cobalt chromium molybdenum or copper which can interfere with biological samples The flow downstream of the sample introduction contains no metals whatsoever Table2 Bio inert Materials Module Materials Agilent 1260 Infinity Bio inert Quaternary Pump Titanium gold platinum iridium G5611A ceramic ruby PTFE PEEK Agilent 1260 Infinity Bio inert High Performance Autosampler Upstream of sample introduction G5667A Titanium gold PTFE PEEK ceramic Downstream of sample introduction PEEK ceramic Agilent 1260 Infinity Bio inert Manual Injector PEEK ceramic G5628A Agilent 1260 Infinity Bio inert Analytical Fraction Collector PEEK ceramic PTFE G5664A Agilent 1290 Infinity Valve Drive and Valve Heads 21 1 Introduction to the Agilent 1290 Infinity Valve Drive and Valve Heads Table2 Bio inert Materials Module Materials Bio inert Flow Cells Standard flow cell bio inert 10 mm 13 pl 120 bar 12 MPa PEEK ceramic sapphire PTFE for MWD DAD includes Capillary Kit Flow Cells BIO p n G5615 68755 p n G5615 60022 for Agilent 1260 Infinity Diode
51. ged ps pre swaged sh short fitting Ig long fitting xlg extra long fitting Agilent 1290 Infinity Valve Drive and Valve Heads Parts and Materials 8 Capillary Kit 5067 4682 Table 12 Capillary Kit PN 5067 4682 Part Number Connection Amount SST cap 0 12 mm ID 340 mm pre swaged p n 5067 4684 Autosampler to Valve 1 SST Capillary 700 x 0 17 mm ps ps 1sh 1xlg p n 5067 4648 Pump to valve ACR 1 only SST cap 0 12 mm ID 90 mm pre swaged p n 5067 4685 Valve to heat 2 exchanger SST cap 0 12 mm ID 150 mm non swaged p n 5067 4686 Short column to valve 2 SST cap 0 12 mm ID 280 mm non swaged p n 5067 4687 Long column to valve 1 SST cap 0 12 mm ID 120 mm pre swaged p n 5067 4688 Valve to valve 1 bypass SST cap 0 12 mm ID 200 mm pre swaged p n 5067 4689 Valve to detector 1 TUBING FLEX p n 0890 1713 Valve to waste 2 Heater long up 0 12 mm i d 1 6 pL internal volume p n G1316 80002 1 Heater long down 0 12 mm i d 1 6 uL internal volume p n G1316 80003 1 Carrier for heat exchanger TCC SL Plus p n G1316 89200 Fitting holder assembly p n G1316 68706 2 Plastic fittings p n 0100 1259 4 Column clip set 8 colors p n 5042 9918 1 Bag plastics p n 9222 0518 1 Agilent 1290 Infinity Valve Drive and Valve Heads 99 8 Parts and Materials Capillary Kit 5067 4729 Table 13 Capillary Kit PN 5067 4729 Part Number Amount Unit Connection SST Capillary 0 8 mm x 0 11 mm340 mm RF M4 p n 50
52. h Algae Algae deposit and grow everywhere within the HPLC system causing Blocked solvent filters or deposits on inlet or outlet valves resulting in unstable flow composition or gradient problems or a complete failure of the pump Small pore high pressure solvent filters usually placed before the injector to plug resulting in high system pressure PTFE frits blockage leading to increased system pressure Column filters to plug giving high system pressure Flow cell windows of detectors to become dirty resulting in higher noise levels since the detector is the last module in the flow path this problem is less common 50 Agilent 1290 Infinity Valve Drive and Valve Heads Using the Module 4 Symptoms Observed with the Agilent 1260 Infinity HPLC The presence of algae in the Agilent 1260 Infinity can cause the following to occur Increased system pressure caused by clogging of the inline filter Algae deposits are barely visible on the stainless steel filter frit Replace the frit if the backpressure of the pump in purge mode water 2 5 mL min exceeds 20 bar Short lifetime of solvent filters bottle head assembly A blocked solvent filter in the bottle especially when only partly blocked is more difficult to identify and may show up as gradient performance problems intermittent pressure fluctuations etc Algae growth may also be the possible source for failures of the ball valves and other components in th
53. he specified line voltage only The module is partially energized when switched off as long as the power cord is plugged in Repair work at the module can lead to personal injuries e g electrical shock when the cover is opened and the module is connected to power Always unplug the power cable before opening the cover gt Do not connect the power cable to the instrument while the covers are removed CAUTION Inaccessible power plug In case of emergency it must be possible to disconnect the instrument from the power line at any time gt Make sure the power connector of the instrument can be easily reached and unplugged Provide sufficient space behind the power socket of the instrument to unplug the cable 26 Agilent 1290 Infinity Valve Drive and Valve Heads Site Requirements and Specifications 2 Power Cords Different power cords are offered as options with the module The female end of all power cords is identical It plugs into the power input socket at the rear The male end of each power cord is different and designed to match the wall socket of a particular country or region Absence of ground connection or use of unspecified power cord The absence of ground connection or the use of unspecified power cord can lead to electric shock or short circuit gt Never operate your instrumentation from a power outlet that has no ground connection gt Never use a power cord other than the Agilent Tec
54. hnologies power cord designed for your region Use of unsupplied cables Using cables not supplied by Agilent Technologies can lead to damage of the electronic components or personal injury Never use cables other than the ones supplied by Agilent Technologies to ensure proper functionality and compliance with safety or EMC regulations Unintended use of supplied power cords Using power cords for unintended purposes can lead to personal injury or damage of electronic equipment gt Never use the power cords that Agilent Technologies supplies with this instrument for any other equipment Agilent 1290 Infinity Valve Drive and Valve Heads 27 2 Site Requirements and Specifications Bench Space The module dimensions and weight see Table 3 on page 29 allow you to place the module on almost any desk or laboratory bench It needs an additional 2 5 cm 1 0 inches of space on either side and approximately 8 cm 8 1 inches in the rear for air circulation and electric connections If the bench shall carry a complete HPLC system make sure that the bench is designed to bear the weight of all modules The module should be operated in a horizontal position Condensation CAUTION Condensation within the module Condensation will damage the system electronics gt Do not store ship or use your module under conditions where temperature fluctuations could cause condensation within the module 2 f your module was shipped
55. if a valve head has been already installed Otherwise continue with Installing Valve heads 40 Agilent 1290 Infinity Valve Drive and Valve Heads Installing the Module 3 Mounting the Valve to a G1383A Column Organizer For more information about the column organizer read the G1383 90011 Column Organizer Quick Reference Guide Attach the column stand mount to the column organizer Attach both clamps to one side of the valve drive Install the leak tray and leak sensor to the valve Slide the valve onto the column stand mount ao A Q N Attach the waste tubing to the leak plane and guide it to a proper waste container e Connect the power cable to the power connector at the rear of the module 7 Connect the CAN interface connection to one of the CAN ports at the rear of the module 8 Power on the module by switching the Power button at the rear of the module if a valve head has been already installed Otherwise continue with Installing Valve heads Agilent 1290 Infinity Valve Drive and Valve Heads 41 3 Installing the Module Installing the Valve Heads 42 The valve drives are factory installed in the thermostatted column compartment and in the 1290 infinity valve drive The valve heads are interchangeable and can be easily mounted At the first installation the transportation lock TCC only and the dummy valve have to be removed see Removing the Transportation Lock and the Valve Dummy on pag
56. ific Information G1170A Initial firmware main and resident Compatible with 1100 1200 series modules Conversion to emulation A 06 40 All other modules must have firmware revision A 06 4x or B 06 4x or above main and resident Otherwise the communication will not work N A Agilent 1290 Infinity Valve Drive and Valve Heads Agilent 1290 Infinity Valve Drive and Valve Heads 8 Parts and Materials Valve Drive Parts 92 Valve Options Overview 94 Accessory Kit 96 Valve Products 97 Capillary Kits 98 Tubing Kit 106 2 Pos 6 Port Valve Head 600 bar 107 2 Pos 6 Port Ultra High Pressure Valve Head 1200 bar 108 2 Pos 6 Port Valve Head 600 bar Bio inert 109 2 Pos 10 Port Micro Valve Head 600 bar 110 2 Pos 10 Port Ultra High Pressure Valve Head 1200 bar 111 8 Pos 9 Port Valve Head 600 bar 112 8 Pos 9 Port Ultra High Pressure Valve Head 1200 bar 113 Valve Head 4 Column Selector 600 bar Bio inert 114 Valve Head 6 Column Selector 600 bar 115 Valve Head 6 Column Selector 1200 bar 116 12 Pos 13 Port Valve Head 210 bar Bio inert 117 This chapter provides information on parts and materials te Agilent Technologies 91 Parts and Materials Valve Drive Parts 92 Item p n 1 5043 0275 2 5067 4792 3 5043 0271 4 5043 0270 5 5068 0106 2110 1486 6 5067 4634 7 5067 1510 Description Clamp guide For attaching the valve to a rail assembly Leak sensor assembly External leak sensor Holder leak plane L
57. igital ground NC 2 Brown Prepare run Low 80 i 3 3 Gray Start Low E o NC 4 Blue Shut down Low o e e i NC 5 Pink Not connected le NC 6 Yellow Power on High 5 14 7 Red Ready High 1 8 Green Stop Low NC 9 Black Start request Low 13 15 Not connected Agilent Module to 3396 Series II 3395A Integrators Use the cable Agilent module to 3396A Series I integrators p n 03394 60600 and cut pin 5 on the integrator side Otherwise the integrator prints START not ready Agilent 1290 Infinity Valve Drive and Valve Heads Identifying Cables 9 Agilent Module to 3396 Series III 3395B Integrators p n 03396 61010 Pin 33XX Pin Agilent Signal Name Active module TTL 9 1 White Digital ground NC 2 Brown Prepare run Low 80 3 3 Gray Start Low x NC 4 Blue Shut down Low o e e NC 5 Pink Not connected le NC 6 Yellow Power on High p 14 7 Red Ready High 4 8 Green Stop Low NC 9 Black Start request Low 13 15 Not connected Agilent Module to Agilent 35900 A D Converters p n 5061 3378 Pin 35900 A D Pin Agilent Signal Name Active module TTL 1 White 1 White Digital ground 2 Brown 2 Brown Prepare run Low 3 Gray 3 Gray Start Low 4 Blue 4 Blue Shut down Low 5 Pink 5 Pink Not connected 6 Yellow 6 Yellow Power on High 7 Red 7 Red Ready High 8 Green 8 Green Stop Low 9 Black 9 Black Star
58. igns of damage 4 Replace the proposed part Always mind the correct orientation of the parts and avoid to touch their surfaces 5 Turn each of the screws an equal amount until they are finger tight then tighten them for another half turn Agilent 1290 Infinity Valve Drive and Valve Heads Maintenance 7 Replacing the Fuses of the Infinity Valve Drive When Tools required Parts required If the valve drive shows no reaction Description Screwdriver p n Description 2 2110 1486 Fuse 2 AT250 V Electrical shock gt Disconnect the valve drive from line power before changing a fuse or trying to open the hatch of the power input socket gt Never re connect the line power before having the power input socket closed 1 Switch off the instrument The line switch is located at 2 Disconnect the power cable from the power input socket the rear of the valve drive 16680666 16 Agilent 1290 Infinity Valve Drive and Valve Heads 83 7 Maintenance 3 To access the fuse drawer gently lift the outer plastic housing of the power inlet socket using a flat screwdriver o m X 4 Pull out the fuse drawer as shown 5 Replace the defect fuse s 6 Slide in the fuse drawer and push till it fits tightly 84 Agilent 1290 Infinity Valve Drive and Valve Heads Maintenance 7 Replacing the Fuses of the Infinity Valve Drive 7 Finally close the fuse dra
59. in cold weather leave it in its box and allow it to warm slowly to room temperature to avoid condensation 28 Agilent 1290 Infinity Valve Drive and Valve Heads Physical Specifications Site Requirements and Specifications 2 Table3 Physical Specifications Type Specification Comments Weight 1 9 kg 4 3 Ibs Dimensions height x width x depth Line voltage Line frequency Power consumption Ambient operating temperature Ambient non operating temperature Humidity Operating altitude Non operating altitude Safety standards IEC CSA UL 95 x 95 x 300 3 7 x 3 7 x 11 8 inches 100 240 VAC 10 Wide ranging capability 50 or 60 Hz 5 20VA 4W 14BTU 4 55 C 39 131 F 40 70 C 4 158 F lt 95 at 25 40 C 77 104 F Non condensing Up to 2000 m 6562 ft Up to 4600 m 15091 ft For storing the module Installation category II Pollution degree 2 For indoor use only Agilent 1290 Infinity Valve Drive and Valve Heads 29 2 Site Requirements and Specifications Performance Specifications Table4 Performance Specifications Agilent 1290 Infinity Valve Drive Type Specification Comments External leak sensor YES Same functionality as internal sensor Fuse 2 0 A250 V High Breaking Capacity Fuse exchangeable Valve types All Agilent Quick Change refer to Table 5 on page 30 Valve heads Valve identification By RFID tag For valve type pressure rating serial num
60. ltaneous analysis on one column while a second identical column is flushed and equilibrated Agilent 1290 Infinity Valve Drive and Valve Heads Introduction to the Agilent 1290 Infinity Valve Drive and Valve Heads 1 Typical Applications Position 1 3 Column 2 Eluent 10 pump Autosampler Waste Regeneration Detector pump Column 1 Position 2 Column 2 Eluent pump Autosampler Regeneration gt Detector pump Column 1 Figure 6 Alternating Column Regeneration Agilent 1290 Infinity Valve Drive and Valve Heads 19 1 Introduction to the Agilent 1290 Infinity Valve Drive and Valve Heads Typical Applications With sequential Analysis 1 Regene Analysis 2 Regene Analysis 3 regeneration ys OC Eee 0 eee MENNEEEEEEEEEEEE ST p W kofemthg ao esl Regene Analysis 3 regeneration n Analysis2 Regene Figure 7 Alternate Column Regeneration Time Scheme Solvent Selection The 12pos 13port valve p n G4235A can be used for solvent selection flow rate lt 10 mL min as illustrated in Figure 8 on page 20 It offers automated access to 12 different eluents up to 12 bottles Pump Figure 8 Solvent Selection Schematic Setup 20 Agilent 1290 Infinity Valve Drive and Valve Heads Introduction to the Agilent 1290 Infinity Valve Drive and Valve Heads 1 Bio inert Materials For the Agilent 1260 Infinity Bio inert LC system Agilent Technologies uses highest quality materials in the flow path also re
61. ly less than the displayed values as EMF limits and then reset the EMF counters to zero The next time the EMF counters exceed the new EMF limits the EMF flag will be displayed providing a reminder that maintenance needs to be scheduled Agilent 1290 Infinity Valve Drive and Valve Heads 23 1 24 Introduction to the Agilent 1290 Infinity Valve Drive and Valve Heads Early Maintenance Feedback Agilent 1290 Infinity Valve Drive and Valve Heads Agilent 1290 Infinity Valve Drive and Valve Heads ee 2 Site Requirements and Specifications o o E e e i e j Site Requirements 26 e Physical Specifications 29 Performance Specifications 30 This chapter provides information on environmental requirements physical and performance specifications ORE Agilent Technologies 25 2 Site Requirements and Specifications Site Requirements A suitable environment is important to ensure optimal performance of the instrument Power Considerations The module power supply has wide ranging capability It accepts any line voltage in the range described in Table 3 on page 29 Consequently there is no voltage selector in the rear of the module There are also no externally accessible fuses because automatic electronic fuses are implemented in the power supply Hazard of electrical shock or damage of your instrumentation can result if the devices are connected to a line voltage higher than specified gt Connect your instrument to t
62. messages and provides information on probable causes and suggested actions how to recover from error conditions RE Agilent Technologies 65 6 Error Information What Are Error Messages Error messages are displayed in the user interface when an electronic mechanical or hydraulic flow path failure occurs which requires attention before the analysis can be continued for example repair or exchange of consumables is necessary In the event of such a failure the red status indicator at the front of the module is switched on and an entry is written into the module logbook 66 Agilent 1290 Infinity Valve Drive and Valve Heads General Error Messages Error Information General error messages are generic to all Agilent series HPLC modules and may show up on other modules as well Timeout Error ID 0062 The timeout threshold was exceeded Probable cause 1 The analysis was completed successfully and the timeout function switched off the module as requested 2 Anot ready condition was present during a sequence or multiple injection run for a period longer than the timeout threshold Agilent 1290 Infinity Valve Drive and Valve Heads Suggested actions Check the logbook for the occurrence and source of a not ready condition Restart the analysis where required Check the logbook for the occurrence and source of a not ready condition Restart the analysis where required 6 67 6 68 Error Informati
63. mperature The corrosion of flow cell windows can negatively affect measurement results For a pH greater than 12 the use of flow cells with sapphire windows is recommended Gold Gold is inert to all common HPLC solvents acids and bases within the specified pH range It can be corroded by complexing cyanides and concentrated acids like aqua regia a mixture of concentrated hydrochloric and nitric acid Zirconium Oxide Zirconium Oxide ZrO9 is inert to almost all common acids bases and solvents There are no documented incompatibilities for HPLC applications Platinum Iridium Platinum Iridium is inert to almost all common acids bases and solvents There are no documented incompatibilities for HPLC applications Agilent 1290 Infinity Valve Drive and Valve Heads 55 4 56 Using the Module PTFE PTFE polytetrafluorethen is inert to almost all common acids bases and solvents There are no documented incompatibilities for HPLC applications Sapphire Ruby and Al 03 based ceramics Sapphire ruby and ceramics based on Al50s are inert to almost all common acids bases and solvents There are no documented incompatibilities for HPLC applications Data above were collected from external resources and are meant as a reference Agilent cannot guarantee the completeness and correctness of such information Information can also not be generalized due to catalytic effects of impurities like metal ions complexing agents oxygen et
64. mplex matrices such as biological fluids food extracts and waste water Before injection into a LC or LC MS system the sample matrix must be separated from the analytes of interest Otherwise contaminants can disrupt separation and detection or even damage the analytical column Agilent 1290 Infinity Valve Drive and Valve Heads 15 1 Introduction to the Agilent 1290 Infinity Valve Drive and Valve Heads Typical Applications PumpA Autosampler Analytical column Position 1 r2 Detector Enrichment Pump B column PumpA Autosampler 1 Analytical 6 column Position 2 Detector Enrichment Pump B column Figure 4 Sample enrichment 16 Agilent 1290 Infinity Valve Drive and Valve Heads Introduction to the Agilent 1290 Infinity Valve Drive and Valve Heads Typical Applications PumpA Autosampler Analytical column Detector Position 1 Pump B Pump A Autosampler ae Analytical column Detector Position 2 Figure 5 Sample clean up Agilent 1290 Infinity Valve Drive and Valve Heads 1 17 1 18 Introduction to the Agilent 1290 Infinity Valve Drive and Valve Heads Enrichment methods Enrichment methods are the technique of choice to obtain highest sensitivity and to remove the sample matrix in such applications as proteomics drug metabolism and environmental trace analysis The analytes are retained and concentrated onto the pre column while the sample matrix is passed to w
65. n nickel cobalt chromium molybdenum or copper which can interfere with biological samples The flow downstream of the sample introduction contains no metals whatsoever However there are no materials that combine suitability for versatile HPLC instrumentation valves capillaries springs pump heads flow cells etc with complete compatibility with all possible chemicals and application conditions This section recommends the preferred solvents Chemicals that are known to cause issues should be avoided or exposure should be minimized for example for short term cleaning procedures After potentially aggressive chemicals have been used the system should be flushed with compatible standard HPLC solvents PEEK PEEK Polyether Ether Ketones combines excellent properties with regard to biocompatibility chemical resistance mechanical and thermal stability and is therefore the material of choice for biochemical instrumentation It is stable in the specified pH range and inert to many common solvents There is still a number of known incompatibilities with chemicals such as chloroform methylene chloride THF DMSO strong acids nitric acid gt 10 sulphuric acid gt 10 sulfonic acids trichloroacetic acid halogenes or aequous halogene solutions phenol and derivatives cresols salicylic acid etc When used above room temperature PEEK is sensitive to bases and various organic solvents which can cause it to swell As normal P
66. nce 76 Cautions and Warnings 77 Overview of Maintenance 79 Cleaning the Module 80 Replacing Parts of the Valve Head 81 Replacing the Fuses of the Infinity Valve Drive 83 Replacing Valve Heads 86 Replacing the Module Firmware 90 Parts and Materials 91 Valve Drive Parts 92 Valve Options Overview 94 Accessory Kit 96 Valve Products 97 Capillary Kits 98 Tubing Kit 106 2 Pos 6 Port Valve Head 600 bar 107 2 Pos 6 Port Ultra High Pressure Valve Head 1200 bar 108 2 Pos 6 Port Valve Head 600 bar Bio inert 109 2 Pos 10 Port Micro Valve Head 600 bar 110 2 Pos 10 Port Ultra High Pressure Valve Head 1200 bar 111 8 Pos 9 Port Valve Head 600 bar 112 8 Pos 9 Port Ultra High Pressure Valve Head 1200 bar 113 Valve Head 4 Column Selector 600 bar Bio inert 114 Valve Head 6 Column Selector 600 bar 115 Valve Head 6 Column Selector 1200 bar 116 12 Pos 13 Port Valve Head 210 bar Bio inert 117 Identifying Cables 119 Cable Overview 120 Analog Cables 122 Remote Cables 124 BCD Cables 127 CAN LAN Cables 129 External Contact Cable 130 Agilent Module to PC 131 Agilent 1290 Infinity Valve Drive and Valve Heads Contents 10 Hardware Information 133 Electrical Connections 134 Interfaces 137 Config Switch Settings of the Infinity Valve Drive 144 11 Appendix 147 General Safety Information 148 The Waste Electrical and Electronic Equipment Directive 151 Radio Interference 152 Sound Emission 153 Agilent Technologies on Internet 1
67. need to be protected from dust and other pollutions Pollution of these parts can impair the accurate selection of valve ports and therefore bias measurement results gt Always install a valve head for operation and storage For protecting the actuator a dummy valve head part of Transportation Lock Kit p n G1316 67001 can be used instead of a functional valve Do not touch parts inside the actuator CAUTION Column Damage or Bias Measurement Results Switching the valve to a wrong position can damage the column or bias measurement results gt Fit the lobe to the groove to make sure the valve is switched to the correct position CAUTION Valve Damage Using a low pressure valve on the high pressure side can damage the valve gt When using multiple column compartments as part of a method development solution make sure that the high pressure valve head is connected to the autosampler and the low pressure valve head is connected to the detector CAUTION Sample degradation and contamination of the instrument Metal parts in the flow path can interact with the bio molecules in the sample leading to sample degradation and contamination For bio inert applications always use dedicated bio inert parts which can be identified by the bio inert symbol or other markers described in this manual gt Do not mix bio inert and non inert modules or parts in a bio inert system Agilent 1290 Infinity Valve Drive and Valve
68. nt Column Organizer G13834A 8 Agilent 1290 Infinity Valve Drive and Valve Heads Introduction to the Agilent 1290 Infinity Valve Drive and Valve Heads 1 Overview of the Valve Drive Figure 1 Mounting Examples for 1290 Infinity Valve Drive Agilent 1290 Infinity Valve Drive and Valve Heads 9 1 Introduction to the Agilent 1290 Infinity Valve Drive and Valve Heads Overview of the Valve Drive Clamps attachable to both sides 1290 Infinity Valve Drive Status indicator Changeable valve head Leak sensor Attachable leak plane 10 Agilent 1290 Infinity Valve Drive and Valve Heads Introduction to the Agilent 1290 Infinity Valve Drive and Valve Heads 1 Overview of the Valve Drive External leak sensor connector Config switch CAN ports Power switch Power connector Figure 2 Rear View of 1290 Infinity Valve Drive Agilent 1290 Infinity Valve Drive and Valve Heads 11 1 Introduction to the Agilent 1290 Infinity Valve Drive and Valve Heads Overview of the Agilent Quick Change Valve Heads 12 BIO Linert The Agilent Quick Change Valve Heads can be installed to the G1316C 1290 Infinity TCC G4227A 1290 Infinity Flexible Cube and to the G1170A 1290 Infinity Valve Drive For bio inert modules use bio inert parts only Table 1 Overview of the available Agilent Quick Change Valve Kits Valve Kit P
69. ome mineral acids For more information see Sovent Information Incompatible with concentrated mineral acids compatible with pH less than 10 compatible with most organics may expe rience swelling with some organics containing functional groups such as nitro benzene at elevated temperatures pre column volume G4234A B 0 51 pL G5639A 0 81 uL post column volume G4234A B 1 28 uL G5639A 1 33 pL Shipping and Storage Temperature 40 80 C Shipping storing or operating this valve below 0 C with water in the fluid passages may cause failure of the sealing surfaces Operating valves above their maximum pressure limit will harm them Please set a corresponding max pressure limit in your Chromatographic Data System if a valve is positioned in the high pressure path Agilent 1290 Infinity Valve Drive and Valve Heads 31 2 Site Requirements and Specifications Performance Specifications 32 Agilent 1290 Infinity Valve Drive and Valve Heads Agilent 1290 Infinity Valve Drive and Valve Heads ee 3 Installing the Module o o E e e i e j Unpacking the Module 34 e Installing the Valve Drive 36 Installing the Valve Heads 42 This chapter gives information about the installation of the valve drive and the valve heads RE Agilent Technologies 33 3 Installing the Module Unpacking the Module Damaged Packaging If the delivery packaging shows signs of external damage please call your Agilent Technologies sales and
70. on Shutdown Error ID 0063 An external instrument has generated a shutdown signal on the remote line The module continually monitors the remote input connectors for status signals A LOW signal input on pin 4 of the remote connector generates the error message Probable cause 1 Leak detected in another module with a CAN connection to the system 2 Leak detected in an external instrument with a remote connection to the system 3 Shut down in an external instrument with a remote connection to the system Remote Timeout Error ID 0070 Suggested actions Fix the leak in the external instrument before restarting the module Fix the leak in the external instrument before restarting the module Check external instruments for a shut down condition A not ready condition is still present on the remote input When an analysis is started the system expects all not ready conditions for example a not ready condition during detector balance to switch to run conditions within one minute of starting the analysis If a not ready condition is still present on the remote line after one minute the error message is generated Probable cause 1 Not ready condition in one of the instruments connected to the remote line 2 Defective remote cable 3 Defective components in the instrument showing the not ready condition Suggested actions Ensure the instrument showing the not ready condition is installed correctly and is
71. ortant data Do not proceed beyond a CAUTION notice until the indicated condi tions are fully understood and met A WARNING notice denotes a hazard It calls attention to an operating procedure practice or the like that if not correctly performed or adhered to could result in personal injury or death Do not proceed beyond a WARNING notice until the indi cated conditions are fully under stood and met Agilent 1290 Infinity Valve Drive and Valve Heads Contents Contents 1 Introduction to the Agilent 1290 Infinity Valve Drive and Valve Heads 7 Overview of the Valve Drive 8 Overview of the Agilent Quick Change Valve Heads 12 Typical Applications 13 Bio inert Materials 21 Early Maintenance Feedback 23 2 Site Requirements and Specifications 25 Site Requirements 26 Physical Specifications 29 Performance Specifications 30 3 Installing the Module 33 Unpacking the Module 34 Installing the Valve Drive 36 Installing the Valve Heads 42 4 Using the Module 49 Hints for Successful Use 50 Solvent Information 52 Software Configuration 57 5 Troubleshooting and Diagnostics 61 Overview of the Module s Indicators and Test Functions 62 Module Status Indicator 63 Agilent Lab Advisor Software 64 6 Error Information 65 What Are Error Messages 66 General Error Messages 67 Module Specific Error Messages 72 Agilent 1290 Infinity Valve Drive and Valve Heads Contents 7 Maintenance 75 Introduction to Maintena
72. ouch parts inside the actuator The tag reader reads the valve head properties from the valve head RFID tag during initialization of the module Valve properties will not be updated if the valve head is replaced while the module is on Selection of valve port positions can fail if the instrument does not know the properties of the installed valve To have the valve correctly recognized by the Agilent Infinity Valve Drive you must have the valve drive powered off for at least 10 seconds Agilent 1290 Infinity Valve Drive and Valve Heads 87 7 Maintenance Replacing Valve Heads 1 Switch off the module 2 Push the valve head for bringing it to its outer position TCC only 3 Remove all capillary connections from the valve head 4 Unscrew the valve head 5 Put the new valve head onto the valve drive such that the lobe fits to the groove see also Installing the Valve Heads on page 42 6 Screw the valve head onto the valve drive using the union nut see also Installing the Valve Heads on page 42 Agilent 1290 Infinity Valve Drive and Valve Heads Maintenance 7 Replacing Valve Heads 7 Install all required capillary connections to the valve head 8 Push the valve head until it snaps in and stays in the rear position 9 Switch on the module Agilent 1290 Infinity Valve Drive and Valve Heads 89 7 Maintenance Replacing the Module Firmware Table 8 Module Spec
73. pos 13port 5067 4159 10 32 n a n a Bio 210 bar G5631A 2pos 6port 5067 4148 10 32 n a 5067 4767 Bio 600 bar G5639A Apos 10port 5067 4134 10 32 n a 5067 4769 600 bar Agilent 1290 Infinity Valve Drive and Valve Heads 97 8 Parts and Materials Capillary Kits Capillary Kit 5067 4646 Table 11 Common capillary kit Part Number Connection Amount SST Capillary 340 x 0 12 mm ps ps 1sh 1xlg p n 5067 4647 SST Capillary 700 x 0 17 mm ps ps 1sh 1xlg p n 5067 4648 SST Capillary 90 x 0 12 mm ps ps 1sh 1xlg p n 5067 4649 SST Capillary 150 x 0 12 mm ns ps 1lg 1xlg p n 5067 4650 SST Capillary 280 x 0 12 mm ns ps 1lg 1xlg p n 5067 4651 Autosampler to valve 1 2 pump to valve 1 Valve to heat 2 exchanger Short column to valve 2 Long column to valve 2 SST Capillary 120 x 0 12 mm ps ps 1xlg 1xlg p n 5067 4652 Valve to valve 1 SST Capillary 200 x 0 12 mm ps ps 1sh 1xlg p n 5067 4653 Valve to detector 1 TUBING FLEX p n 0890 1713 Valve to waste 2m Heater long up 0 12 mm i d 1 6 pL internal volume p n G1316 80002 1 Heater long down 0 12 mm i d 1 6 uL internal volume p n G1316 80003 1 Carrier for heat exchanger p n G1316 89200 2 Fitting holder assy includes following items Fitting fork fitting clip 2 screws pack of 4 p n G1316 68706 Column clip set 8 colors p n 5042 9918 1 Plastic fittings p n 0100 1259 4 Bag plastics p n 9222 0518 1 98 Fittings ns not pre swa
74. r p n 5067 4159 Bio inert valve head 4 column selector 600 bar p n 5067 4134 Bio inert rotor seal and stator face kit p n 0101 1288 Bio inert rotor seal PEEK p n 5068 0045 Bio inert stator head p n 5068 0097 Bio inert stator head p n 5068 0044 1 kit with stator face and rotor seal Agilent 1290 Infinity Valve Drive and Valve Heads 95 8 Parts and Materials Accessory Kit Accessory Kit p n G1170 68705 p n Description 5043 0270 Leak plane 5043 0271 Holder leak plane 5067 4792 Leak sensor assembly 5181 1519 CAN cable Agilent module to module 1 m 5043 0275 2x Clamp guide 2110 1486 2x Fuse 2 AT250 V 96 Agilent 1290 Infinity Valve Drive and Valve Heads Valve Products Parts and Materials 8 Valve kit P N Valve type Valve P N Supported Capillary Kits Capillary Kits Fitting size ID 0 12 mm ID 0 17 mm G4230A 8pos 9port 5067 4107 10 32 5067 1595 5067 1596 600 bar 5067 1597 G4230B 8pos 9port 5067 4107 10 32 5067 1595 5067 1596 600 bar 5067 1597 8pos 9port 5067 4121 10 32 1200 bar G4231A 2pos 6port 5067 4137 10 32 5067 4646 5067 4730 600 bar G4231B 2pos 6port 5067 4117 10 32 5067 4646 n a 1200 bar G4232A 2pos 10port 5067 4144 M4 5067 4800 5067 5103 600 bar micro G4232B 2pos 10port 5067 4118 10 32 5067 4682 n a 1200 bar G4234A 6pos l4port 5067 4146 M4 5067 4729 n a 600 bar G4234B 6pos l4port 5067 4142 M4 5067 4729 n a 1200 bar G4235A 12
75. re for analysis for example calibration detector lamp on Receiver is any module performing pre analysis activities 3 START L Request to start run timetable Receiver is any module performing run time controlled activities 4 SHUT DOWN L System has serious problem for example leak stops pump Receiver is any module capable to reduce safety risk 5 Not used 6 POWER ON H All modules connected to system are switched on Receiver is any module relying on operation of others 7 READY H System is ready for next analysis Receiver is any sequence controller 8 STOP L Request to reach system ready state as soon as possible for example stop run abort or finish and stop injection Receiver is any module performing run time controlled activities 9 START REQUEST L Request to start injection cycle for example by start key on any module Receiver is the autosampler Special Interfaces Some modules have module specific interfaces connectors They are described in the module documentation Agilent 1290 Infinity Valve Drive and Valve Heads 143 10 Hardware Information Config Switch Settings of the Infinity Valve Drive Config Switch Settings of the Infinity Valve Drive closed open Dipswitch 1 Dipswitch 2 Figure25 Config Switches Dipswitch 1 Dipswitch 2 Function open open Default Standard Operation Mode open closed Forced Cold Start closed open Resident Mode closed closed Not Supported 144 Agil
76. regulations Analog cables p n Description 35900 60750 Agilent module to 3394 6 integrators 35900 60750 Agilent 35900A A D converter 01046 60105 Analog cable BNC to general purpose spade lugs Remote cables p n Description 03394 60600 Agilent module to 3396A Series integrators 3396 Series Il 3395A integrator see details in section Remote Cables on page 124 03396 61010 Agilent module to 3396 Series III 3395B integrators 5061 3378 Remote Cable 01046 60201 Agilent module to general purpose BCD cables p n Description 03396 60560 Agilent module to 3396 integrators G1351 81600 Agilent module to general purpose Agilent 1290 Infinity Valve Drive and Valve Heads Identifying Cables 9 CAN cables p n Description 5181 1516 CAN cable Agilent module to module 0 5 m 5181 1519 CAN cable Agilent module to module 1 m LAN cables p n Description 5023 0203 Cross over network cable shielded 3 m for point to point connection 5023 0202 Twisted pair network cable shielded 7 m for point to point connection External Contact Cable p n Description G1103 61611 External contact cable Agilent module interface board to general purposes RS 232 cables p n Description G1530 60600 RS 232 cable 2 m RS232 61600 RS 232 cable 2 5 m Instrument to PC 9 to 9 pin female This cable has special pin out and is not compatible with connecting printers and plotters It s also called Null Modem Cable with
77. reme caution when handling testing and adjusting When working with solvents observe appropriate safety procedures for example goggles safety gloves and protective clothing as described in the material handling and safety data sheet by the solvent vendor especially when toxic or hazardous solvents are used Agilent 1290 Infinity Valve Drive and Valve Heads 149 11 Appendix Safety Symbols Table 23 Safety Symbols Symbol Description The apparatus is marked with this symbol when the user should refer to the N instruction manual in order to protect risk of harm to the operator and to protect the apparatus against damage Indicates dangerous voltages Indicates a protected ground terminal Indicates eye damage may result from directly viewing the light produced Z by the deuterium lamp used in this product The apparatus is marked with this symbol when hot surfaces are available and the user should not touch it when heated up KITE UMS alerts you to situations that could cause physical injury or death Do not proceed beyond a warning until you have fully understood and met the indicated conditions CAUTION A CAUTION alerts you to situations that could cause loss of data or damage of equipment gt Do not proceed beyond a caution until you have fully understood and met the indicated conditions 150 Agilent 1290 Infinity Valve Drive and Valve Heads Appendix 11 The Waste Electrical and Ele
78. s should be reduced to the minimum required for the analysis gt Do not operate the instrument in an explosive atmosphere WARNING Electrical shock Repair work at the module can lead to personal injuries e g shock hazard when the cover is opened gt Do not remove the cover of the module gt Only certified persons are authorized to carry out repairs inside the module WARNING Personal injury or damage to the product Agilent is not responsible for any damages caused in whole or in part by improper use of the products unauthorized alterations adjustments or modifications to the products failure to comply with procedures in Agilent product user guides or use of the products in violation of applicable laws rules or regulations gt Use your Agilent products only in the manner described in the Agilent product user guides Agilent 1290 Infinity Valve Drive and Valve Heads 77 7 Maintenance CAUTION Safety standards for external equipment gt If you connect external equipment to the instrument make sure that you only use accessory units tested and approved according to the safety standards appropriate for the type of external equipment CAUTION Sample degradation and contamination of the instrument Metal parts in the flow path can interact with the bio molecules in the sample leading to sample degradation and contamination gt For bio inert applications always use dedicated bio inert parts
79. service office immediately Inform your service representative that the instrument may have been damaged during shipment CAUTION Defective on arrival problems If there are signs of damage please do not attempt to install the module Inspection by Agilent is required to evaluate if the instrument is in good condition or damaged Notify your Agilent sales and service office about the damage gt An Agilent service representative will inspect the instrument at your site and initiate appropriate actions 34 Agilent 1290 Infinity Valve Drive and Valve Heads Installing the Module 3 Delivery Checklist Ensure all parts and materials have been delivered with your module The delivery checklist is shown below For parts identification please check the illustrated parts breakdown in Parts and Materials on page 91 Please report any missing or damaged parts to your local Agilent Technologies sales and service office Table6 Delivery Checklist Description Quantity 1290 Infinity Valve Drive 1 Valve rail assembly p n 5067 4634 Optional Rail assy for column organizer p n 5067 1510 Optional Agilent LC Hardware Documentation DVD p n 1 G4800 64500 Power cable 1 LAN Interface Card p n G1369 60012 Optional required if no proper hosting module is available see Agilent 1200 Infinity Series Interfaces on page 137 Accessory Kit p n G1170 68705 1 Accessory Kit The 1290 Infinity Valve Drive is shippe
80. spel p n 5068 0012 Rotor Seal PEEK p n 0101 1415 5068 0001 Stator head p n 5068 0001 Stator head p n 5068 0006 Stator head p n 0101 1417 Stator head p n 5068 0011 Stator Head p n 0101 1421 Agilent 1290 Infinity Valve Drive and Valve Heads Table 9 Agilent Quick Change Valve Heads Parts and Materials 8 Kit description Valve head Rotor seal Stator heads 6 column selector valve p n G4234A 6 column selector p n G4234B Valve head 6 column selector 600 bar p n 5067 4146 Valve head 6 column selector 1200 bar p n 5067 4142 Rotor seal PEEK p n 5068 0076 Rotor seal Vespel p n 5068 0067 Stator Head p n 5068 0077 Stator Head p n 5068 0077 Valve kits include the valve head optional capillary kits manual access material and installation and familiarization service For more details refer to the Parts and Material section G4230A includes 2 x 8Pos 9Port 600bar valve heads G4230B includes 1x 8Pos 9Port 600bar and 1x 8Pos 9Port 1200bar valve head Table 10 Agilent Quick Change Valve heads Bio inert Kit description Valve head Rotor seal Stator heads 2pos 6port valve bio inert p n G5631A 12pos 13port valve bio inert p n G4235A 6 column selector valve bio inert p n G5639A Bio inert valve head 2 pos 6 port 600 bar p n 5067 4148 Bio inert selector valve 12 position 13 port 210 ba
81. status indicator is red An error condition indicates the module has detected an internal problem which affects correct operation of the module Usually an error condition requires attention e g leak defective internal components An error condition always interrupts the analysis If the error occurs during analysis it is propagated within the LC system i e a red LED may indicate a problem of a different module Use the status display of your user interface for finding the root cause module of the error A blinking indicator indicates that the module is in resident mode e g during update of main firmware A fast blinking indicator indicates that the module is in a low level error mode In such a case try to re boot the module or try a cold start see Config Switch Settings of the Infinity Valve Drive on page 144 Then try a firmware update see Replacing the Module Firmware on page 90 If this does not help a main board replacement is required Agilent 1290 Infinity Valve Drive and Valve Heads 63 5 Troubleshooting and Diagnostics Agilent Lab Advisor Software 64 The Agilent Lab Advisor software is a standalone product that can be used with or without data system Agilent Lab Advisor software helps to manage the lab for high quality chromatographic results and can monitor in real time a single Agilent LC or all the Agilent GCs and LCs configured on the lab intranet Agilent Lab Advisor software provides diagnostic
82. t request Low Agilent 1290 Infinity Valve Drive and Valve Heads 125 126 Identifying Cables Agilent Module to General Purpose p n 01046 60201 Wire Color Pin Agilent Signal Name Active module TTL White 1 Digital ground A Q 1 Dn Brown 2 Prepare run Low 00 Lu p KEY Gray 3 Start Low oo poe uu S SS dB 4 Shut down Low og Pink 5 Not connected oo BB Yellow 6 Power on High 5 15 Red 7 Ready High Green 8 Stop Low Black 9 Start request Low Agilent 1290 Infinity Valve Drive and Valve Heads Identifying Cables 9 BCD Cables One end of these cables provides a 15 pin BCD connector to be connected to the Agilent modules The other end depends on the instrument to be connected to Agilent Module to General Purpose p n G1351 81600 Wire Color Pin Agilent Signal Name BCD Digit module Green 1 BCD 5 20 Violet 2 BCD7 80 p 1 Blue 3 BCD 6 40 ERR Yellow 4 BCD 4 10 SS Black 5 BCD 0 1 MCN Orange 6 BCD 3 8 Red 7 BCD2 4 Brown 8 BCD 1 2 Gray 9 Digital ground Gray Gray pink 10 BCD 11 800 Red blue 11 BCD 10 400 White green 12 BCD 9 200 Brown green 13 BCD 8 100 notconnected 14 notconnected 15 5V Low Agilent 1290 Infinity Valve Drive and Valve Heads 127 9 Identifying Cables Agilent Module to 3396 Integrators p n 03396 60560 Pin 3396 Pin Agilent Signal Name BCD Digit module n 1 1 BCD 5 20 ae 2
83. tenance requires the exchange of components which are subject to wear or stress Ideally the frequency at which components are exchanged should be based on the intensity of usage of the module and the analytical conditions and not on a predefined time interval The early maintenance feedback EMF feature monitors the usage of specific components in the instrument and provides feedback when the user selectable limits have been exceeded The visual feedback in the user interface provides an indication that maintenance procedures should be scheduled EMF Counters EMF counters increment with use and can be assigned a maximum limit which provides visual feedback in the user interface when the limit is exceeded Some counters can be reset to zero after the required maintenance procedure Using the EMF Counters The user settable EMF limits for the EMF Counters enable the early maintenance feedback to be adapted to specific user requirements The useful maintenance cycle is dependent on the requirements for use Therefore the definition of the maximum limits need to be determined based on the specific operating conditions of the instrument Setting the EMF Limits The setting of the EMF limits must be optimized over one or two maintenance cycles Initially the default EMF limits should be set When instrument performance indicates maintenance is necessary take note of the values displayed by the EMF counters Enter these values or values slight
84. tion 29 156 power consideration 26 power cords 27 R radio interference 152 remote cable 124 repairs definition of 76 introduction 76 warnings and cautions 76 RS 232C cable 131 S safety class 148 safety general information 148 standards 29 symbols 150 serial number information 134 shutdown 68 site requirements 25 power cords 27 solvent information 54 sound emission 153 special interfaces 143 special settings boot resident 145 forced cold start 145 specification physical 29 specifications 25 wavelength accuracy 30 status indicator 63 T temperature sensor 71 Agilent 1290 Infinity Valve Drive and Valve Heads test functions 62 time table 60 timeout 67 troubleshooting error messages 66 62 status indicators 62 U unpacking 34 V voltage range 29 WwW waste electrical and electronic equipment 151 WEEE directive 151 weight 29 www agilent com In This Book This User s Guide describes common applications as well as installation operation and maintenance of the Agilent Infinity Valve Drive and Agilent Quick Change Valve heads Agilent Technologies 2011 2012 Printed in Germany 05 2012 G1170 90001 Rev B RES Agilent Technologies
85. ty Valve Drive and Valve Heads Appendix 11 the instrument must be made inoperative and be secured against any intended operation Make sure that only fuses with the required rated current and of the specified type normal blow time delay and so on are used for replacement The use of repaired fuses and the short circuiting of fuse holders must be avoided Some adjustments described in the manual are made with power supplied to the instrument and protective covers removed Energy available at many points may if contacted result in personal injury Any adjustment maintenance and repair of the opened instrument under voltage should be avoided whenever possible When inevitable this has to be carried out by a skilled person who is aware of the hazard involved Do not attempt internal service or adjustment unless another person capable of rendering first aid and resuscitation is present Do not replace components with power cable connected Do not operate the instrument in the presence of flammable gases or fumes Operation of any electrical instrument in such an environment constitutes a definite safety hazard Do not install substitute parts or make any unauthorized modification to the instrument Capacitors inside the instrument may still be charged even though the instrument has been disconnected from its source of supply Dangerous voltages capable of causing serious personal injury are present in this instrument Use ext
86. ule s Indicators and Test Functions Status Indicators The module is provided with two status indicators which indicate the operational state prerun run and error states of the module The status indicators provide a quick visual check of the operation of the module Error Messages In the event of an electronic mechanical or hydraulic failure the module generates an error message in the user interface For each message a short description of the failure a list of probable causes of the problem and a list of suggested actions to fix the problem are provided see chapter Error Information Test Functions A series of test functions are available via the Lab Advisor Software for troubleshooting and operational verification 62 Agilent 1290 Infinity Valve Drive and Valve Heads Troubleshooting and Diagnostics 5 Module Status Indicator The module status indicator indicates one of six possible module conditions When the status indicator is OFF and power switch light is on the module is in a prerun condition and is ready to begin an analysis A green status indicator indicates the module is performing an analysis run mode A yellow indicator indicates a not ready condition The module is in a not ready state when it is waiting for a specific condition to be reached or completed for example immediately after changing a set point or while a self test procedure is running An error condition is indicated when the
87. warranty terms covering the material in this document that conflict with these terms the warranty terms in the sep arate agreement shall control Technology Licenses The hardware and or software described in this document are furnished under a license and may be used or copied only in accor dance with the terms of such license Restricted Rights Legend If software is for use in the performance of a U S Government prime contract or subcon tract Software is delivered and licensed as Commercial computer software as defined in DFAR 252 227 7014 June 1995 or as a commercial item as defined in FAR 2 101 a or as Restricted computer soft ware as defined in FAR 52 227 19 June 1987 or any equivalent agency regulation or contract clause Use duplication or dis closure of Software is subject to Agilent Technologies standard commercial license terms and non DOD Departments and Agencies of the U S Government will receive no greater than Restricted Rights as defined in FAR 52 227 19 c 1 2 June 1987 U S Government users will receive no greater than Limited Rights as defined in FAR 52 227 14 June 1987 or DFAR 252 227 7015 b 2 November 1995 as applicable in any technical data Safety Notices CAUTION A CAUTION notice denotes a hazard It calls attention to an operating procedure practice or the like that if not correctly per formed or adhered to could result in damage to the product or loss of imp
88. wer housing reconnect the instrument to the power line and switch it on Agilent 1290 Infinity Valve Drive and Valve Heads 85 7 Maintenance Replacing Valve Heads Several optional valve heads are available which can be installed and exchanged easily Micro valves offer small internal volumes for minimum peak broadening ideal for low flow rates in the nl min and ul min range For bio inert modules use bio inert parts only Linert Parts required p n Description 1 5067 4121 8 pos 9 port valve head high pressure 1200 bar OR 1 5067 4107 Valve Head 8 Position 9 Port 600 bar OR 1 5067 4137 Valve Head 2 Postion 6 Port 600 bar OR 1 5067 4117 2 pos 6 port ultra high pressure 1200 bar valve head OR 1 5067 4144 Micro Valve Head 2 Position 10 Port 600 bar OR 1 5067 4118 2 pos 10 port ultra high pressure 1200 bar valve head OR 1 5067 4146 Valve head 6 column selector 600 bar OR 1 5067 4142 Valve head 6 column selector 1200 bar OR 1 5067 4148 Bio inert valve head 2 pos 6 port 600 bar OR 1 5067 4134 Bio inert valve head 4 column selector 600 bar OR 1 5067 4159 Bio inert selector valve 12 position 13 port 210 bar WARNING Toxic flammable and hazardous solvents samples and reagents The handling of solvents samples and reagents can hold health and safety risks gt Be sure that no solvent can drop out of the solvent connections when removing them from your valve head gt When working with
89. which can be identified by the bio inert symbol or other markers described in this manual gt Do not mix bio inert and non inert modules or parts in a bio inert system 78 Agilent 1290 Infinity Valve Drive and Valve Heads Maintenance 7 Overview of Maintenance The following pages describe maintenance procedures simple repairs that can be done without opening the main cover Table 7 Maintenance Procedures Procedure Typical Frequency Notes Cleaning the Module on If required page 80 Replacing Parts of the Valve If leak sensor is defect Head on page 81 Replacing the Fuses of the When a fuse is defect Infinity Valve Drive on page 83 Replacing Valve Heads on If the valve performance shows page 86 indication of leakage or wear Replacing the Module If required Firmware on page 90 Agilent 1290 Infinity Valve Drive and Valve Heads 79 7 Maintenance Cleaning the Module To keep the module case clean use a soft cloth slightly dampened with water or a solution of water and mild detergent WARNING Liquid dripping into the electronic compartment of your module can cause shock hazard and damage the module gt Do not use an excessively damp cloth during cleaning Drain all solvent lines before opening any connections in the flow path 80 Agilent 1290 Infinity Valve Drive and Valve Heads Maintenance 7 Replacing Parts of the Valve Head BIO Linert When Tools r

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