Capit-All Integrated System
Contents
1. 3 4 Capit All ScrewTop Tube Capper Decapper Thermo Scientific Parts Chapter 3 Example 1 Nunc 96 Way 1ml tube rack configuration Tube rack Rack Nest amp Spacer 063 0005 Example 2 Matrix 96 Way 0 5ml Cap Tray configuration Cap Tray 4477 Cap Tray Lifter 063 0C096 Thermo Scientific Capit All ScrewTop Tube Capper Decapper 3 5 Chapter 3 Parts 3 3 2 Configurations for the Capit All Integrated System IS The following table specifies the Rack Nest amp Spacers required for a given tube type Note Capit All IS does not support the use of uncapped tubes with cap trays 96 Way Capit All systems Capit All part Capit All Tube type Rack Nest amp number description description Spacer 4111NUN IS Capit All IS Nunc 96 Way 374082 374083 374086 063 0050 063 3F1A Automation 0 5ml 374087 and equivalents Friendly Screw A 9311 Cap Decapper for Nunc 96 way tubes Nunc 96 Way 374084 374085 374088 063 0C05 1 0ml 374089 and equivalents A 9321 4111MAT IS Capit All IS Matrix 96 Way 3748 063 0D93 063 3G1A Automation 0 2ml Friendly Screw Matrix 96 Way 3744 GRE YEL BLU RED WHI 063 0C52 Cap Decapper for g 5m PUR Matrix 96 way tubes A 9611 Matrix 96 Way 3741 GRE YEL BLU RED WHI 063 0C06 1 0ml PUR A 9621 4114NUN IS Capit All IS Nunc 48 Way 374221 Lock In 374223 063 0C95 for 063 3F4A Automation2. Control Panel Direction of Opening Open Door Rack of Microtubes Rack Nest and Spacer Door Base Capit All ScrewTop Tube Capper Decapper 3 1 Chapter 3 Parts Cycle Counter Drip Tray Extraction port Vacuum Connector Service amp Support function only 3 2 Capit All Integrated System IS 3 3 Racks Rack Nest Spacers and Cap Tray Lifters Racks Rack Nest amp Spacers and Cap Tray Lifters have been designed to support a wide range of different tube types and cap trays and these are summarized below for the Bench top and Integrated System versions of the Capit All instrument Note Cap Tray Lifters are accessories that support the use of Nunc and Matrix cap trays with the Capit All Bench top system They are not compatible with Capit All Integrated System IS due to the requirement to physically constrain the cap tray within the lifter 3 3 1 Configurations for the Capit All Bench top system The following table specifies the Racks Rack Nest amp Spacers and Cap Tray Lifters required for a given tube and cap type and this is followed by an illustration showing how these are combined in a typical configuration 3 2 Capit All ScrewTop Tube Capper Decapper Thermo Scientific Note TAP part numbers are given in square brackets 3 3 1 1 96 Way Capit All systems Capit All part number Capit All description Tube type description Rack Nest amp Spacer Parts Chapter 3
3. Cap Tray Lifter 4111NUN Capit All Nunc 96 Way 374082 374083 063 0C50 063 1F1A Screw Cap 0 5ml 374086 374087 and Decapper for A 9311 equivalents Nunc 96 way Cryobank vials Nunc 96 Way 374084 374085 063 0C05 1 0ml 374088 374089 and equivalents A 9321 Nunc 96 Way 374102 063 0050 0 5ml uncapped Nune 96 Wa 374021 Blue 019 N12030 unc 36 ay Red 018 Green 017 sap tray ha Green 063 0C93 Nunc 96 Way 374103 063 0005 1 0ml uncapped nese 374021 Blue 019 N12031 unc Yo Way Red 018 Green 017 cap tray aon Green 063 0092 4111MAT Capit All Matrix 96 Way 3748 063 0D93 Screw Cap 0 2ml Decapper for 063 1G1A A 96F1 l l Matrix 96 way l tubes Matrix 96 Way 3744 GRE YEL BLU RED 063 0052 0 5ml WHI PUR A 9611 Matrix 96 Way 3741 GRE YEL BLU RED 063 0C06 1 0ml WHI PUR A 9621 Matrix 96 Way 3745 63 0052 0 5ml uncapped 4905 empty 4477 Neutral GRE YEL 4090 Matrix 96 Way BLUE RED WHI PUR cap tray 063 C096 Matrix 96 Way 3742 063 0C06 1 0ml uncapped 4905 empty 4477 Neutral GRE YEL 4091 Matrix 96 Way BLUE RED WHI PUR cap tray 063 C097 Thermo Scientific Capit All ScrewTop Tube Capper Decapper 3 3 Chapter 3 Parts 3 3 1 2 48 Way Capit All systems Capit All part number 4114NUN 063 1F4A Capit All description Capit All Screw Cap Decapper for Nunc
4. 1 General requirements Declaration declare that as the authorised representative the above machine complies with the Machinery Directive 2006 42 EC Annex 1 Section 2 1 the Low Voltage Directive 2006 95 EC and its amendments and the Electromagnetic Compatibility Directive 2004 108 EC and its amendments Name of authorised representative Justin Owen Position of authorised representative era Signature of authorised representative IS Date 13th February 2012 TAP Biosystems York Way Royston Hertfordshire SG8 5WY United Kingdom A2 2 Capit All ScrewTop Tube Capper Decapper Thermo Scientific Certifications Appendix 2 A2 2 Capit All IS EC Certificate of Conformity di Biosystems Capit All IS EC Declaration of Conformity Brief Description of the Product Automated bench top product for decapping recapping screw cap micro tubes incorporating a rack transfer axis for moving racks from the robotically accessible loading position to and from the capping head Standards used in the design and manufacture of Capit All IS BS EN ISO 12100 1 2 Safety of machinery Basic concepts general principles for design BS EN ISO 14121 1 Safety of machinery Risk Assessment BS EN ISO 953 Safety of machinery General requirements for the design and construction of guards fixed movable BS EN ISO 13849 1 2 Safety of machinery Safety related parts of control systems EN 1088 Safety of machinery Interl
5. 2 0ml Lock In Lock In tube Friendly Screw Or racks Cap Decapper for Or Nunc 48 way tubes 374221 374223 Nunc 48 Way 374220 Lock In 374222 063 0C94 for 5 0ml Lock In Lock In tube Or racks 374220 374222 or A 9281 063 0D94 3 6 Capit All ScrewTop Tube Capper Decapper Thermo Scientific Parts Chapter 3 3 4 Installation Drawings 3 4 1 Capit All Unit Capit Al Shown Upside Down MK6 Capit All Base Details 3 4 2 Capit All IS Unit Thermo Scientific Capit All ScrewTop Tube Capper Decapper 3 7 Chapter 3 Parts The following table illustrates the height that the labware will sit Dimension A in the drawing above Capit All Part No s Type of rack Capacity Rack Nest Spacer s 4111NUN Lock In 0 5ml 063 0C50 86mm 4111NUN IS 1 0ml 063 0C05 72 8mm 4111MAT Lock In 0 2ml 063 0D93 98mm 4111MAT IS 0 5ml 063 0C52 81mm 1 0ml 063 0C06 67mm 4114NUN Lock In 2 0ml 063 0C95 71 8mm 4114NUN IS 5 0ml 063 0094 29 8mm Non lock in 2 0ml 063 0D95 70 3mm 5 0ml 063 0D94 28 3mm 3 8 Capit All ScrewTop Tube Capper Decapper Thermo Scientific Chapter 4 Operation 4 1 Control Panel Buttons Indicators Note The Capit All IS system is shown for illustrative purposes a pF wo N Buttons Indicators Function 1 Power Indicator Continuously illuminated
6. 48 way Cryobank vials Tube type description Nunc 48 Way 2 0ml internal thread 374221 Lock In 374223 Lock In or 374221 374223 A 9251 Rack Nest amp Spacer or 063 0095 for Lock In tube racks 063 0D95 Nunc 48 Way 5 0ml internal thread 374220 Lock In 374222 Lock In or or 063 0C94 for Lock In tube racks 374220 374222 063 0D94 A 9281 Nunc 48 Way 1 8ml 374500 2D coded 063 0D95 external thread 374501 uncoded 3 3 1 3 24 Way Capit All systems Capit All part Capit All Tube type Rack Nest amp number description description Spacer 4113NUN Capit All Nunc 24 Way 1 8ml 347627 375418 063 0016 063 0067 Cap Decapper A 9142 for Nunc external thread Nunc 24 Way 4 5ml 347643 337516 063 0015 063 0081 tubes external thread A 9172 001 C1081 F 4112NUN Capit All Nunc 24 Way 1 8ml 377267 063 0C16 063 0067 063 1F3A 24 Way Screw internal thread A 9141 001 C1083 F Cap Decapper for Nunc internal thread Nunc 24 Way 4 5ml 379146 063 0C15 063 0C84 tubes internal thread A 9171 001 C1081 F and 063 0C81 4113NAL Capit All Nalgene 24 Way 5000 1012 063 0019 063 0065 24 Way Screw 1 0ml external A 9623 063 C1100 C Cap Decapper thread for Nalgene Nalgene 24 Way 5000 1020 063 0014 063 0064 System100 45m external A 96B3 063 C1151 C tubes thread
7. All unit is supplied with a Rack 24 Way only Rack Nest amp Spacer and Spacer s To configure these items correctly 1 Identify the exact volume and size of tubes that are to be used 2 Using the table and illustration given in Section 2 identify the correct configuration of Rack 24 Way only Rack Nest amp Spacer and Spacer s and assemble them as indicated The Rack Nest amp Spacer is placed directly onto the Rack Nest Carriage followed by the tube rack or Rack 24 Way only If using a Cap Tray this is loaded directly into the Cap Tray Lifter that in turn is placed onto the Rack Nest amp Spacer Note When installing the Capit All IS system it may be necessary to attach the Rack Nest Carriage To do this locate the moveable Rack Nest Carriage mounting bracket positioned alongside the carriage This will normally be in the loading position but if it has moved during transit it can be repositioned by hand provided that there is no power to the unit The mounting bracket has two bars that locate with sockets at the back of the Rack Nest Carriage Attach the Rack Nest Carriage and press firmly home ensuring that it is flat parallel with the carriage The Rack Nest amp Spacer and tube rack or Rack 24 Way only may then be loaded onto the Rack Nest Carriage Note Once the correct Rack Nest amp Spacer is assembled into the unit subsequent tube racks or Racks 24 Way only may be loaded and unloaded without further
8. R FF move or the relevant sensor has not eset 0 been activated Stop OFF Decap OFF Head Motor An error has occurred within the head Recap OFF motor Reset ON The motor has failed to move or the relevant sensor has not been activated Stop OFF Decap OFF Drip Tray Inserted The drip tray is inserted when a decap or recap operation has been requested Recap OFF i Reset ON If drip tray has been physically hi removed then this indicates an issue Stop ON with the sensor Decap OFF Stripper Plate Raised The stripper plate is in its raised Recap ON position prior to moving the head and nut plate for a decap or recap operation Reset OFF l e the stripper plate sensors are Stop OFF activated Capit All ScrewTop Tube Capper Decapper A1 1 Appendix 1 Fault Codes Light Pattern Description Decap OFF Stripper Plate Engage The stripper plate has failed to engage Recap ON Reset OFF Stop ON Decap OFF Stripper Plate Disengage The stripper plate has failed to Recap ON disengage Reset ON Stop OFF Decap OFF Nut Plate Sensors One or more of the three nut plate Recap ON sensors has been found to be on when the nut plate is at a different location Reset ON Stop ON Capit All IS Additional Faults Light Pattern Description Decap ON Rack Shuttle Enable The rack transfer shuttle has failed to Re
9. a connection to the unit send an Abort command to flush out any characters that may have previously been sent to the unit Thermo Scientific Capit All ScrewTop Tube Capper Decapper 5 3 Chapter 5 External Control 5 1 7 2 Reset R The reset command i Returns the rack transfer axis to the loading position ii Returns the head mechanics to the pre start position After successful completion of the command the state of the unit is Ready Caution Before resetting the system the user should check that the unit is clear of obstructions Caution Any caps in the system will be retained after a reset These caps will cause a problem if the next action is to decap a rack 5 1 7 3 Status S The status command returns the status of the unit The response to the status command is one of e BUSY lt CR gt lt LF gt e FAULT lt CR gt lt LF gt e READY lt CR gt lt LF gt The state of the unit is not changed by this command 5 1 7 4 Decap D The Decap command decaps a rack located on the Carriage and returns it to the Load Position After successful completion of the command the state of the unit is Ready 5 1 7 5 Recap C Recaps a rack located on the Carriage and returns it to the Load Position After successful completion of the command the state of the unit is Ready 5 1 7 6 eXtended Recap X Recaps a rack located on the Carriage and returns it to the Load Position As well as recapping the rack this command perfor
10. at the address given in the Contacts section of this User Manual 2 1 Unpacking Instructions 1 Inspect the tip and tell and shock watch indicators on the outside of the carton and if these indicate mishandling during transportation inform Thermo Fisher immediately and take special care to inspect the enclosed items for damage If damage is observed or if you have any doubts about the safety or integrity of the unit inform Thermo Fisher immediately 2 Carefully remove the tape and banding across the lid of the carton using a knife or heavy duty cutter Detach the lid and lift the side section cleanly off and away from the base 7 Thermo Scientific Capit All ScrewTop Tube Capper Decapper 2 1 Chapter 2 Unpacking 3 Remove the small box of ancillary items usually fixed by double sided tape from the base of the carton 4 Using the 6mm Allen key provided remove the four screws holding the two transit brackets to the carton base but leave them attached to the Capit all unit at this time y 5 With the aid of two or more people carefully remove Capit All unit from the carton discard the outer polythene bag and conduct a visual check for signs of damage during transit Inform Thermo Fisher Scientific immediately if there are any damaged or loose items 6 Using the 5mm Allen key provided remove the four screws holding the two transit brackets to the Capit All base 7 fin the future you need to relocat
11. to reconfigure the COM ports on the client e g PC to ensure successful communication with the Capit All IS unit The following sections give the specification for the RS232 interface and if you require further information please contact Thermo Fisher Scientific at the address given in the Contacts section of this User Manual 5 1 1 Hardware specification 9 pin D socket Pin No Function 2 RX 3 TX 5 GND Outer screen Screen Capit All ScrewTop Tube Capper Decapper 5 1 Chapter 5 External Control 5 1 2 Baud rate The Baud rate is factory pre set at 9600 5 1 3 RS232 cable An RS232 cable is supplied with the Capit All IS system This is 9 way D male to female pins 2 and 3 swapped at one end pin 5 and the screen are connected straight through separately 5 1 4 State Model The unit has three main states e Fault is the initial state when the unit is switched on after an Abort command or after a fault e Ready is the state when the unit is ready to decap or cap a rack of tubes e Busy is the state when the unit is performing an operation Internally there are different states depending on the operation being performed The diagram below shows the valid commands in the different states It is the responsibility of the client software to know if it is appropriate to Cap or to Recap at any particular point in time These commands may be initiated either over the remote RS232 interface or by but
12. 2 Load the tube rack to be decapped into the Rack Nest amp Spacer 3 Perform a Decap function by pressing the Decap front panel button or remotely using the instructions given in the External Control section of this User Manual Note The Decap Indicator light will stop flashing when the operation is complete 4 Remove the decapped tube rack The caps will remain inside the Capit All unit ready for capping 4 5 5 Capping using the Capit All Integrated System IS 1 Load the tube rack to be capped into the Rack Nest amp Spacer 2 Perform a Recap function by pressing the Recap front panel button or remotely using the instructions given in the External Control section of this User Manual Note The Recap Indicator light will stop flashing when the operation is complete 3 Remove the capped tube rack 4 6 Discarding decapped caps The User may collect discarded caps by replacing the Rack 24 Way only and Rack Nest amp Spacer with a suitable container e g the lid from an SBS format rack or Cap Tray 4 6 1 Discarding caps into a container 1 Remove the Rack 24 Way only and Rack Nest amp Spacer and replace with a suitable container Note A suitable container is not supplied with the Capit All system 2 Follow the instructions above for capping 3 Open the Door and remove the container holding the discarded caps 4 6 2 Discarding caps into a Cap Tray Remove the Rack Nest amp Spacer Loa
13. Cap Tray into the Cap Tray Lifter by carefully loosening one of the supporting plastic retaining springs and slipping it into place Ensure that the Cap Tray sits horizontally within the Cap Tray Lifter and is in the correct orientation If it s not the Cap Tray will not sit properly in the Cap Tray Lifter and will fail to be decapped or recapped properly Load the Cap Tray Lifter onto the Rack Nest amp Spacer 4 4 Use of the Drip Tray To reduce the likelihood of cross contamination caused by drops of liquid on the decapped caps falling into neighboring tubes the Capit All Bench top version has a manual Drip Tray and the Integrated System has an automated one Note The Drip Tray is detachable and is NOT necessary for correct operation of the Capit All system but may be useful in some applications When the Drip Tray is detached the instructions below for decapping recapping should be followed but just omit those specifically relating to this function 4 4 1 Removal replacement of drip tray Bench top version Detach the Drip Tray by carefully pulling it out of the unit using the serrated handle designed for this purpose Replace by inserting it back into the unit ensuring in its final position that it s firmly home 4 4 2 Removal replacement of drip tray IS version Release the small clip under the Drip Tray see diagram below and detach by carefully pulling it out of the unit using the serrated handle designed for
14. SCIENTIFIC CAPIT ALL Thermo Scientific Capit All ScrewTop Tube Capper Decapper October 2014 jenuew sas This page intentionally left blank Chapter 1 Chapter 2 Chapter 3 Chapter 4 Chapter 5 Chapter 6 Chapter 7 Chapter 8 Appendix 1 Appendix 2 Table of Contents NOCES sra ta de 1 1 A EAS E ete AO 1 1 Hie POWER amp Sse sos laa citas 1 2 1 3 Operating CONGIIONS aici hai cir ta ded bse a kw era a de in 1 2 A E RO 1 3 1 5 Contact Detalla il EAEE a 1 3 Unpacking vocacion ni a id a 2 1 2 1 Unpacking Instructions ooooo ooooooroncoo ro 2 1 2 2 PANS Stout daria dada 2 3 A hw eect alms Dist indecent mbar yO inc tat Cyn wpa au ne Ounce a Sy 3 1 3 1 Capit All Bench top system onon cc eect eee tre etn eee ens 3 1 3 2 Capit All Integrated System IS 0 cece eee ete eee ens 3 2 3 3 Racks Rack Nest amp Spacers and Cap Tray LifferS 6 cee ee 3 2 34 InStallatloniDFAWINGS 4 iaa ai ad 3 7 OPEL ON ori a a li da all ala A 4 1 4 1 Control Panel Buttons IndicatorS ooocooocooooooocoro eee ens 4 1 4 2 Basic OPENS eri a A A AA AI EN EE a a 4 1 AS ONO Cab MS esere ra Aa 4 5 AA USE Or Me Dip MAY ua id died aE 4 5 4 5 DeCappinG CAPPING coi a oa doe an dasha wea downey 4 6 4 6 Discarding decapped CAPS nannaa 4 7 External GONTOl ooo a a aca ada 5 1 5 1 RS232 interface Capit All IS unit only eect eee eens 5 1 A OE 5 1 5 3 Connecting to Instrument 0 eet tee treet eee
15. adjustment 3 Load the system with tubes as follows 4 2 7 1 Loading racks of tubes 96 and 48 Way operation Place the tube rack into the Rack Nest amp Spacer ensuring that there is a good fit and that the rack sits horizontally in the nest When loading the rack ensure that it s in the correct orientation i e column 1 is on the left column 12 on the right If it s not in this orientation the rack will not sit properly in the Rack Nest amp Spacer and will fail to be decapped or recapped properly 4 2 7 2 Loading loose tubes 24 Way operation Load the tubes by hand into the mounting holes in the Rack Note It is very important when loading tubes by hand that they are seated correctly and failure to do so may cause the Capit All instrument to enter a fault condition To prevent this carefully rotate each of the tubes until the anti rotation feature on the base of the tube locates with the holes in the base of the Rack 4 4 Capit All ScrewTop Tube Capper Decapper Thermo Scientific Operation Chapter 4 4 3 Loading Cap Trays Cap Tray Lifters are available to support Nunc and Matrix Cap Trays for use with racks of uncapped tubes from the same vendors To configure these items correctly 1 Identify the exact volume and size of tubes that are to be used 2 Using the table and illustration given in Section 2 identify the correct configuration of Cap Tray Cap Tray Lifter and Rack Nest amp Spacer Place the
16. as specified by the labware manufacturer These clutches gradually wear with time If the unit has decapped and capped more than 10 500 cycles as measured by the Cycle Counter for 48 and 96 way configured systems or 7 500 cycles for 24 way units the clutches will need to be refurbished and please contact Thermo Fisher Scientific 8 2 Capit All ScrewTop Tube Capper Decapper Thermo Scientific Thermo Scientific Appendix 1 Fault Codes The following tables identify the fault codes which are communicated via the system lights When a fault is detected the Recap and Reset indicator lights flash alternately with the Decap and Stop lights to alert the user to the fault condition The specific fault code is then displayed one hexadecimal digit at a time starting with the most significant digit using these light patterns Each digit is displayed for approximately 10 seconds If there is another digit to display then all four lights flash together for a short period and then the next digit is displayed This display cycle is repeated until the instrument is reset The Capit All IS unit has some additional fault codes which are not applicable to the standard Capit All unit these are identified in the second table Capit All and Capit All IS Faults Light Pattern Description Decap OFF Nut Plate Motor An error has occurred within the nut Recap OFF plate motor The motor has failed to
17. cap OFF enable correctly Reset OFF Stop OFF Decap ON Rack Shuttle Initialize The rack transfer shuttle has failed to Recap OFF either initialize reset or home correctly Reset OFF Stop ON Decap ON Rack Shuttle Move The rack transfer shuttle has failed to AAA reach its target destination Recap OFF 9 Reset ON Stop OFF Decap ON Drip Tray Initialize The drip tray motor has failed to enable Recap OFF or initialize correctly Reset ON Stop ON Decap ON Drip Tray Move The drip tray motor has failed to Recap ON complete an extend or retract R FF movement or the sensors have not eset 0 detected the drip tray in the correct Stop OFF location Decap ON Software Checksum The checksum calculated by the Recap ON software does not match the checksum R FF value calculated and stored during eset 0 software download Stop ON A1 2 Capit All ScrewTop Tube Capper Decapper Thermo Scientific Fault Codes Appendix 1 Light Pattern Description Decap ON Cover Guard Switches The system has detected that the cover Recap ON guard switches are the inverse of where they should be during an operation i e ResetON the door appears to be open when it Stop OFF should be closed Decap ON Finger Guard Sensors The system has detected that the finger Recap ON guard sensors are the inverse of where they should be during an operation i e Reset ON they are detecting an obstruction when Stop ON
18. d the Cap Tray and Cap Rack Lifter as instructed in Section 4 3 Perform a capping operation Open the Door and remove the Cap Tray holding the discarded caps Pon Thermo Scientific Capit All ScrewTop Tube Capper Decapper 4 7 Chapter 4 Operation This page intentionally left blank 4 8 Capit All ScrewTop Tube Capper Decapper Thermo Scientific Thermo Scientific Chapter 5 External Control The Capit All instrument can be operated in two distinct modes e Manually using the front panel control buttons e Remotely using the RS232 control port Capit All IS only Manual operation has been described earlier in this User Manual so the following sections focus on the instructions to control Capit All IS using the RS232 control port Note The Capit All bench top version is supplied with a 9 pin D socket but this is NOT for customer use It is supplied for diagnostic and servicing purposes by staff from Thermo Fisher Scientific or appointed agents only 5 1 RS232 interface Capit All IS unit only A port 9 pin D socket is located on the side of the Capit All IS unit allowing control of front panel functions using software commands from a suitable client e g PC When using the RS232 interface Capit All IS front panel buttons are enabled and it performs functions on a first come first serve basis The client connects to IS using a standard RS232 cable supplied with the system Note It may be necessary
19. e action has completed with the line OK lt CR gt lt LF gt The unit responds to an invalid remote command or to remote commands that do not complete successfully with an error line of the form below where code is the error code ERcode lt CR gt lt LF gt 5 1 6 Error Codes The following errors may be returned from a command ER1 the unit was busy and the command was ignored ER2 the command was not valid ER3 the command was aborted ER4 general fault the machine failed to complete its requested operation for an unspecified reason ER5 capping head fault the capping head failed to operate ER6 the rack transfer axis has failed to operate 5 1 7 Command Set 5 1 7 1 Abort ESC The abort command brings the unit to a controlled stop as soon as possible The abort command consists of the escape character Any preceding characters are ignored The response to the abort command is an error code serving as acknowledgement both of the Abort command and of any command that was aborted The error code will be ER3 unless another error arises during execution of the Abort Pressing the stop button on the unit while a remotely initiated action is in progress will abort that action and the action will return ER3 Pressing the stop button at other times will not cause any text to be sent over the RS232 interface After successful completion of the command the state of the unit is Fault Note When you first make
20. e the Capit All unit or return it to Thermo Fisher Scientific for servicing or repair you will need to prepare it for transportation using its original packaging It is therefore advisable to store all the packaging fixings and tools supplied with the Capit All system in a safe place for at least one year Note In the event that the packaging becomes lost or damaged please contact Thermo Fisher Scientific for a replacement 2 2 Capit All ScrewTop Tube Capper Decapper Thermo Scientific Unpacking Chapter 2 2 2 Parts List Please check that the following items are present when the unit has been unpacked e Capit All unit e Power cables 3 off to cover applicable international standards e Rack 24 Way only e Rack Nest and Spacer s e Cap Rack Lifter s 96 Way only e RS232 cable Integrated System version only e User Manual Thermo Scientific Capit All ScrewTop Tube Capper Decapper 2 3 Chapter 2 Unpacking This page intentionally left blank 2 4 Capit All ScrewTop Tube Capper Decapper Thermo Scientific Thermo Scientific Chapter 3 Parts The Capit All system contains no user serviceable parts and the following sections summarize the major elements of the Capit All Bench top and Capit All Integrated System IS 3 11 Capit All Bench top system Note the following illustration shows the 96 way version but the 24 and 48 way variants are similar having a larger loading door AC Input
21. eens 5 2 Maintenance ira id A ea 6 1 6 1 Cleaning and Decontamination 0 tet nee es 6 1 Disposal cae a Se nai wink panini a wn mv A ane 7 1 Troubleshooting lt lt lt iii eee ee cen ee tae eee ee ee eee ve 8 1 FAUT GO MS cosa daa A1 1 COTTTICAIONS oc A A E wows Siow eee A2 1 Thermo Scientific Capit All ScrewTop Tube Capper Decapper 3 This page intentionally left blank 4 Capit All ScrewTop Tube Capper Decapper Thermo Scientific Thermo Scientific Chapter 1 Notices 1 1 Safety Before using this equipment ensure that you are properly trained in e The correct and safe operation of of Capit All Capit All IS equipment Safety Standards Capit All and Capit All IS Capper Decappers are CE compliant and certified to NRTL US and Canada standards Safety Labels The equipment has a number of safety labels intended to protect the operator from injury pay attention to these labels at all times These labels are Label Meaning The top cover should only be removed by trained personnel and never without isolating the unit DO NOT remove this cover unless you have received training from the Manufacturer or Supplier to do so No user serviceable parts inside Isolate supply before removing cover The rear panel should only be removed after disconnecting power and only by trained personnel Capit All ScrewTop Tube Capper Decapper 1 1 Chapter 1 Notices K
22. eep clear of operating machinery This label is only visible if the top cover is removed 1 2 Power Caution This equipment requires a protective earth connection The grounding pin must be connected to an earthed ground Use the power cord supplied with the instrument or an alternative cord certified for the country of use The power supply is connected at the back of the right hand side of the instrument as shown below Ensure the power switch is Off 0 before connecting to or disconnecting from the supply A 2222 Capit All power connector location Capit All IS power connector location The equipment is designed for use with the following mains supplies Voltage 110 240VAC Frequency 50 60Hz 1 2 Capit All ScrewTop Tube Capper Decapper Thermo Scientific Notices Chapter 1 1 3 Operating Conditions Operating Temperature 15 C to 30 C Humidity lt 5 RH non condensing 1 4 Warranty Standard warranty is e 12 months Or e 10 500 cap recap cycles as measured by the Cycle Counter for 48 or 96 way compatible systems e 7 500 cap recap cycles as measured by the Cycle Counter for 24 way compatible systems Whichever occurs first Enhanced preventative maintenance and service packages are available For further details please contact Thermo Fisher Scientific at the address given in the Contacts section of this User Manual 1 5 Contact Details N
23. ms any extended functions that may be included in the future e g gas purge After successful completion of the command the state of the unit is Ready 5 4 Capit All ScrewTop Tube Capper Decapper Thermo Scientific Thermo Scientific Chapter 6 Maintenance 6 1 Cleaning and Decontamination The outer surfaces and Drip Tray of the Capit All unit can be cleaned with typical laboratory Cleaning agents and 70 alcohol solutions The system is also tolerant to specific de contamination regimes based on hydrogen peroxide e g that offered by Bioquell Inc The system may be used with samples containing DMSO as a cryo preservative Caution Do not use Formaldehyde as a de contamination agent as this will cause permanent damage to the electronic components within the equipment On a regular basis e g after every production batch remove and clean the Drip Tray and flush out the loading area with clean air from an aerosol can these can be purchased from any general laboratory supplier This will prevent the accumulation of particulates not necessary if the vacuum extraction facility is connected The Drip Tray should then be re inserted Capit All ScrewTop Tube Capper Decapper 6 1 Chapter 6 Maintenance This page intentionally left blank 6 2 Capit All ScrewTop Tube Capper Decapper Thermo Scientific Chapter 7 Disposal 71 WEEE Compliance The Capit All instrument is required to comply with the Euro
24. nal vacuum system 3 Turn the external extraction system ON 4 2 5 Attaching the AC Power Supply 1 Remove the appropriate AC power cable from the Capit All packaging and plug one end into the AC input on the side of Capit All unit and the other into the AC outlet The Capit All unit contains a universal power supply so there is no need to adjust any voltage settings 2 Switch the unit ON using the power switch above the AC input 3 The Power Indicator will light up and after a brief pause the Reset Indicator will light up and the Stop Indicator light will flash 4 To prepare the Capit All capper for use press the Reset button Wait until the Reset Indicator light has stopped flashing and the unit has stopped moving Thermo Scientific Capit All ScrewTop Tube Capper Decapper 4 3 Chapter 4 Operation 4 2 6 Loading Racks of tubes Capit All systems are configured to work with the tube type specified at the time of order Caution Using incorrect tubes may cause damage Please ensure that you always use the correct tubes for the current configuration of the Capit All system System part and serial numbers are printed on a label at the rear of the unit and please refer to Section 2 for configuration information 4 2 7 Configuring the Capit All Capper for different height tubes Tubes are supplied in a variety of different working volumes and sizes To accommodate a range of tube sizes the Capit
25. ocking devices with and without guard locking general principles and provisions for design ISO 10218 1 Robotics for Industrial Environments EN 60204 1 Safety of machinery Electrical equipment of machines Specification of general requirements EN 61326 1 Electrical equipment for measurement control and laboratory use EMC regulations Part 1 General requirements Declaration declare that as the authorised representative the above machine complies with the Machinery Directive 2006 42 EC Annex 1 Section 2 1 the Low Voltage Directive 2006 95 EC and its amendments and the Electromagnetic Compatibility Directive 2004 108 EC and its amendments Name of authorised representative Justin Owen Position of authorised representative Engineerin Signature of authorised representative Date 13 February 2012 TAP Biosystems York Way Royston Hertfordshire SG8 5WY United Kingdom Thermo Scientific Capit All ScrewTop Tube Capper Decapper A2 3 Appendix 2 Certifications A2 3 Capit All and Capit All IS NRTL Certificate CERTIFICATE No U8 14 06 86998 004 Holder of Certificate Tap Biosystems Co York Way Royston Hertfordshire SG8 SWY UNITED KINGDOM Production 86998 Facility ies Certification Mark x o La em c Lat o a a lt i ma gt cc uy de 5 lt x oa bL oo Product Model s Parameters Tested according to Electrical equ f
26. op system 1 Ensure the Drip Tray is fully inserted and load either a tube rack or Rack with tubes to be recapped into the Rack Nest amp Spacer 2 Caution It is still possible to close the Door if the rack of tubes is not in the correct orientation Check that the rack is in the correct orientation by ensuring that it is sitting horizontally in the Rack Nest amp Spacer 3 Gently pull the Drip Tray out until it clicks into its retracted position 4 Perform a Recap function by pressing the Recap front panel button Note The Recap Indicator light will stop flashing when the operation is complete 5 Push the Drip Tray into the unit to return it to its inserted position Open the Door and remove the capped tube rack or Rack with tubes 4 5 3 Using Cap Trays with the Capit All Bench top system Using the instructions for decapping and capping racks of tubes described above 1 Load the Cap Tray as instructed in Section 5 3 2 Perform a decapping operation 3 Remove the Cap Tray and Cap Tray Lifter and replace with a rack of uncapped tubes held in a Rack Nest as specified in the table given in Section 2 4 Perform a capping operation 5 Open the Door and remove the capped rack of tubes 4 6 Capit All ScrewTop Tube Capper Decapper Thermo Scientific Operation Chapter 4 4 5 4 Decapping using the Capit All Integrated System IS 1 Ensure that the correct Rack Nest amp Spacer is in place see Section 2
27. or measurement control and laboratory use Decapper Capper Capit All Capit All IS Fill 1t Rated Input Voltage 100 240 V AC Rated Frequency 50 60 Hz Rated Input Current 6A Protection Class l CANICSA C22 2 No 61010 1 2012 CANICSA C22 2 No 61010 2 81 R 2009 UL 61010 1 2012 EN 61010 1 2001 EN 61010 1 2010 EN 61010 2 081 A1 2003 The product was voluntarily tested according to the relevant safety requirements noted above It can be marked with the certification mark above The mark must not be altered in anyway This product certification system operated by TUV SUD America Inc most closely resembles system 3 as defined in ISOMEC Guide 67 Certification is based on the TOV SUD Testing and Certification Regulations T V SUD America Inc is an OSHA recognized NRTL and a Standards Council of Canada accredited certification body ZERTIFIKAT CERTIFICATE Test report no DI1311124 000 8 o Date 2014 06 27 Y ME A 5 gt 8 Page 1 of 1 Miers pa o S T V SUD AMERICA INC 10 Centennial Drive Peabody MA 01960 USA www TUVamerica com Tov A2 4 Capit All ScrewTop Tube Capper Decapper Thermo Scientific Notes thermoscientific com Thermo 2014 Thermo Fisher Scientific Inc All rights reserved All trademarks are the property of Thermo Fisher Scientific Inc and its subsidiaries Specifications SCIENTIFIC terms and pricing are subject to change Not all products are available in all countries Please cons
28. orth America Contact Main Office Thermo Fisher Scientific 75 Panorama Creek Drive Rochester NY 14625 PH 585 586 8800 1 800 625 4327 technicalsupport thermofisher com Europe Contact Thermo Fisher Scientific Robert Bosch Str 1 63505 Langenselbold Germany PH 49 0 6184 906 000 orders labequipment de thermofisher com Thermo Scientific Capit All ScrewTop Tube Capper Decapper 1 3 Chapter 1 Notices This page intentionally left blank 1 4 Capit All ScrewTop Tube Capper Decapper Thermo Scientific Chapter 2 Unpacking WARNING 1 The weight of the Capit All Bench top unit and Capit All Integrated System IS units is approximately 44kg 97 Ib and 54kg 130 Ib respectively Please ensure that they are handled safely by at least two people and that appropriate lifting methods are employed Always lift the Capit All system by holding its base and never support the weight of the Capit All Integrated System IS using the extended Carriage Failure to do so may cause the heavy base to become detached potentially leading to serious injury Check that all tables safety cabinets or mounting brackets supporting the equipment have been built to accommodate the respective weights N oo Note The following instructions are illustrated for the Capit All Bench top system but they are similar for the Capit All Integrated System IS If you have any questions please contact Thermo Fisher Scientific
29. pean Union s Waste Electrical amp Electronic Equipment WEEE Directive 2002 96 EC and is marked with the following symbol Thermo Fisher Scientific and its agents have contracted with one or more recycling or disposal companies in the European Union EU and these companies will dispose of or recycle this product Please contact Thermo Fisher Scientific at the address given in the Contacts section of this User Manual for further information on compliance with these Directives and the recyclers in your country Thermo Scientific Capit All ScrewTop Tube Capper Decapper 7 1 Chapter 7 Disposal This page intentionally left blank 7 2 Capit All ScrewTop Tube Capper Decapper Thermo Scientific Thermo Scientific Chapter 8 Troubleshooting The Capit All Capper Decapper has been designed to provide trouble free operation but the following information is provided to help diagnose and solve any problems that may occur during its life Note The following is designed for troubleshooting the Capit All Bench top system and it does NOT offer solutions to problems that arise when the Capit All IS system is controlled externally or integrated within a larger automated system For questions of this type please contact Thermo Fisher Scientific at the address given in the Contacts section of this User Manual Symptom The Stop and Reset indicator lights are flashing continuously A fault has been detected with the safety circ
30. they should be clear Thermo Scientific Capit All ScrewTop Tube Capper Decapper A1 3 This page intentionally left blank Thermo Scientific Capit All ScrewTop Tube Capper Decapper A1 4 Appendix 2 Certifications The documetns in this section provide evidence of certifications obtained for the Capit All products Thermo Scientific Capit All ScrewTop Tube Capper Decapper A2 1 Appendix 2 Certifications A2 1 Capit All EC Certificate of Conformity 49 TAP wy Biosystems a TM Capit All EC Declaration of Conformity Brief Description of the Product Automated bench top product for decapping recapping screw cap micro tubes Standards used in the design and manufacture of Capit All BS EN ISO 12100 1 2 Safety of machinery Basic concepts general principles for design BS EN ISO 14121 1 Safety of machinery Risk Assessment BS EN ISO 953 Safety of machinery General requirements for the design and construction of guards fixed movable BS EN ISO 13849 1 2 Safety of machinery Safety related parts of control systems EN 1088 Safety of machinery Interlocking devices with and without guard locking general principles and provisions for design ISO 10218 1 Robotics for Industrial Environments EN 60204 1 Safety of machinery Electrical equipment of machines Specification of general requirements EN 61326 1 Electrical equipment for measurement control and laboratory use EMC regulations Part
31. this purpose Replace by inserting it back into the unit with the serrated handle positioned towards the left hand side of the unit ensure it s firmly home and reapply the small clip holding it in place To operate the instrument without the drip tray disable the automatic drip tray function by pressing and holding the STOP and RESET buttons together for about 5 seconds To re enable automatic drip tray function after refitting it press and hold the STOP and RESET buttons together for about 5 seconds Thermo Scientific Capit All ScrewTop Tube Capper Decapper 4 5 Chapter 4 Operation 4 5 Decapping Capping 4 5 1 Decapping using the Capit All Bench top system 1 Ensure the Drip Tray is fully inserted and if not push it fully in 2 Open the Loading Door Ensure that the correct Rack Nest amp Spacer is in place see Section 2 3 Load either a tube rack or Rack with tubes 24 Way only 4 Fully close the Door 5 Move the Drip Tray into its retracted position by gently pulling it out of the machine until it Clicks into place The Drip Tray does not have to be fully removed from the system 6 Perform a Decap function by pressing the Decap front panel button Note The Decap Indicator light will stop flashing when the operation is complete 7 Open the Door and remove the decapped tubes The caps will be retained within Capit All unit ready for capping 4 5 2 Capping using the Capit All Bench t
32. tion Replace with the correct Rack Nest amp Spacer The tube rack is not in the correct orientation Remove the tube rack from the Rack Nest amp Spacer and rotate the rack by 180 Check that the rack sits horizontally in the Rack Nest amp Spacer The Door will not open The Door will not open A cap has fallen off and is jamming the Loading Door A tube has been lifted out of the rack and remains attached to its cap Turn off the power to the Capit All unit Remove the Loading Door panel see section 5 Recover the tube rack by lifting the Rack Nest amp Spacer and off its locating pins You may need to feel around inside the unit to locate the fallen cap and remove it Replace the Loading Door panel and Rack Nest amp Spacer The unit may now be operated normally Turn off power to the Capit All unit Remove the Loading Door panel see section 5 Use a tool to push the tube and its cap downwards back into the rack A cap has jammed during recap Press the Reset button and remove the rack The cap that has caused the error will not be fully tightened up Manually unscrew the cap and then screw it back up again Replace the rack close the Door and press Recap The Capit All unit is not tightening the caps enough Torque is reaching the limits of the specified range The Capit All unit uses individual clutches to ensure that each cap is tightened to the correct torque
33. tons on the machine In either case the state model is the same The buttons on the machine are illuminated to indicate which commands are available The remote RS232 interface will respond with an error code if the machine is not in a state where a command can be executed Idle N Abort g J N a N Starting State Fault Ready pa y o yl A A A A de i gt OK Decap OK Recap OK Reset Fault or pusy Abort y lt r sZ S Resetting Decapping Recapping No A Ne y Ne o J Note The Status command may be called at any time and will return the current state of the machine 5 2 Capit All ScrewTop Tube Capper Decapper Thermo Scientific External Control Chapter 5 5 1 5 Command Format Commands with the exception of Abort consist of a single uppercase letter identifying the command followed by a linefeed character lt LF gt or a carriage return character lt CR gt Commands may also be terminated with lt CR gt lt LF gt or lt LF gt lt CR gt since the instrument ignores empty commands The unit responds to remote commands that request information e g S with a line containing the information for the command followed by lt CR gt lt LF gt The specific information returned is detailed under the individual commands Note See a following section for the response to the Abort command The unit responds to other valid remote commands once th
34. tubes The procedures for completing this are different for the Bench top and Integrated System versions and these are summarized below Warning Do not exert excessive force to open the Loading Door to gain access or to close Note Capit All Capper will not function without the Loading Door in place 4 2 2 Removing Loading Door Capit All Bench top system Using a screwdriver turn the fastener by one quarter turn then slide the panel out To replace Slide in and refasten checking the panel is secure 4 2 Capit All ScrewTop Tube Capper Decapper Thermo Scientific Operation Chapter 4 4 2 3 Removing Loading Door Capit All Integrated System IS To remove turn the knurled fastener and detach the panel To replace refasten and check that it is secure 4 2 4 Attaching the Vacuum Line optional The Capit All unit has a 19mm outer diameter port that can be connected to a suitable vacuum based extraction system to reduce the possibility of contamination through airborne particulates and evaporates Typically 1 bar of negative pressure is applied Note Attaching a vacuum line is NOT necessary for successful operation of the Capit All equipment but may be useful in some applications 1 Locate the extraction port on the side of the Capit All unit as shown in the diagram in Section 2 of this Manual 2 Attach flexible hosing to the extraction port and connect the other end to the exter
35. uit Solution Turn the machine off and on again If the problem persists contact Thermo Fisher Scientific The Recap and Reset indicator lights flash alternately with the Decap and Stop lights then some or all lights are on solid for 10 seconds A fault has been detected The fault code is determined by the pattern of lights which are on solid for 10 seconds see Appendix for details Note The Fault Mode will be displayed after a cycle of seven flashing fault code displays Contact Thermo Fisher Scientific ideally with details of the Fault Mode who will offer help and remedial action as necessary Press the Reset button to reset the unit The Stop Indicator light is flashing and the Reset Indicator light is lit The Decap and Recap indicators are not lit and pressing the Decap and Recap Buttons has no effect The unit is in Start Up or Fault Mode Press the Reset button The unit will reset and the Decap or Recap Indicator lights will illuminate Upon pressing the Decap or Recap buttons the Capit All unit goes into Fault Mode Reset Indicator lit Stop Indicator flashing The Drip Tray is inserted Ensure that the Drip Tray is fully retracted or removed from the unit Press the Reset button Capit All ScrewTop Tube Capper Decapper 8 1 Chapter 8 Troubleshooting Symptom The Door will not close The wrong Rack Nest amp Spacer is inserted Solu
36. ult your local sales representative for details Part of Thermo Fisher Scientific MNLSPCAPIT ALL 1014
37. when Capit All unit is powered up 2 Decap Button and Indicator Press to Decap tubes 3 Recap Button and Indicator Press to Recap tubes 4 Reset Button and Indicator Press to reset Capit All unit to a known condition 5 Stop Button and Indicator Press to halt the operation of Capit All unit 4 2 Basic Operation 4 2 1 Initial Set Up Unpack Capit All unit as described in the Unpacking Instructions and use the following procedures to set up the system prior to use It is unlikely that there will be any issue with the set up and operation of the Capit All equipment but if you experience any difficulties please refer to Thermo Scientific Capit All ScrewTop Tube Capper Decapper 4 1 Chapter 4 Operation the Troubleshooting section of this manual or request assistance from Thermo Fisher Scientific at the address given in the Contacts section of this manual The Capit All unit features a Cycle Counter which counts every time a capping cycle is completed When you receive your Capit All system the Cycle Counter will already display a number of counts This is due to cycles run during quality control testing If you contact Thermo Fisher Scientific regarding a problem you may be asked to provide the number displayed on the counter Additionally in the highly unlikely that caps are not successfully Decapped or Recapped you may also be asked to remove the panel in the Loading Door to gain access to a rack of
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