DP1000 Bed Anl English V1.8
Contents
1. 7 2 5 NO ARBITRARY CONVERSION WORK OR MODIFICATION WOREN 7 2 6 SUPPLEMENTARY SAFETY INFORMATION 7 2 7 AND LIABILITY 8 3 COMMISSIONING EE 9 3 1 EE 9 3 2 MAINSXCONNECTION EEN 9 3 3 INSERTING THE TUBE FITTING IN THE DPUMP 9 3 4 SCREW ON THE STAND EE EE Ghee aes 9 3 5 RRE I ON ORDRE ETUR 10 3 6 EITAS N O ec ee en as ocean aie es OR DI uia oA D ALL Iu e ne A UTD p ieee DIEI 10 4 OPERATION OF THE DOSIPUMP 1000 ce eee KREE eere ere e eee eee ee o ee eere eere RE ee 11 4 1 FUNDAMENTA EEN 11 4 2 MEANN I SERM NER RT 12 4 3 M LOEO SERI REN 13 4 4 C ALIPRATION MEN EE 24 4 5 EE He 5 PTECHNICALINEOR MATION EE 28 5 1 PN PRODUC WON EE 28 5 2 CLEAN EE 28 5 3 TRANSPORTING THE DOSIPUMP 1000 teeaseec oe taceo eta veo b cete o opt Eh eegene 20 5 4 TION uctus icu IM oe EIL EMIL EE E 20 5 5 TEOUBLESHOOTINGC eser ec Pes ae dede ve e Ee deter 30 5 6 ACCE ORI teats ede sce AA MEI D E ME E LI LAE RU EE 32 5 7 DPTO EE EIN AI IAM ices MA MD M M MM DEM 32 5 8 ELECTRICAICCONNECTIONSa5 EEN 33 5 9 LE TNI IND ET een atone be ess ead tence esi ea eee 34 Page 2 User Manual Version 1 8 DosiPump 1000 User Manual Overview 1 1 Preface further to the User Manual The User Manual exp2. License number There may also be an expiry date for the license number After this date the device is barred until a new license is applied for and the licence code has been entered Page 27 User Manual Version 1 8 DosiPump 1000 User Manual 5 Technical information 5 1 Introduction Chapter Technical information contains additional information on operation of the DOSIPUMP 1000 It is assumed that the unit is operated by a trained DOSIPUMP 1000 user with the required access rights 5 2 Cleaning Cleaning procedures must be performed regularly in order to ensure optimum performance of the DosIPUMP 1000 The cleaning routine described below must not be considered as absolutely essential It serves as a guideline to assist efficient operation of the DOSIPUMP 1000 The decision on when and how to clean must be made by the individual laboratory 5 2 1 Materials required e Washing up liquid use a mixture of one part washing up liquid and three parts water e Deionised water e Soft lint free cleaning cloth and paper tissues Do not use cleaning agents containing acetone or other aggressive cleaning agents nitrocellulose thinners Disconnect the mains plug each time before cleaning 5 2 2 Cleaning procedures Cleaning the unit e Clean the surface of the unit with a lightly moistened cloth e Wipe off the plexiglass covers with a lightly moistened cloth Cleaning the touch screen e The touch screen may be cleaned o
3. depending on tube diameter 1000 ml min tube dependent 0 0 9 9 seconds 0 90 selectable Auto reverse angle of pump head 240 x 128 pixels with LED backlighting 79 dB A IP 21 5 C to 45 C also during transport Sturdy support surface The two footswitch contacts are designed as normally open contacts NO RS232 for connection to host and printer RS485 for BioLink communication with laboratory in struments Stainless steel length 200 mm 12 mm 700000 DosiPump DP 1000 710000 DosiPump DP1000P 720000 DosiPump DP1000PI User Manual Version 1 8
4. German Liability Insurance Associations those of the Heath Authority and those of the Factory Inspectorate must also be followed Page 6 User Manual Version 1 8 DosiPump 1000 User Manual 2 3 Qualification of the operating personnel Specialist technical training is generally required Special knowledge is required when operating the DOSIPUMP 1000 to prevent potentially dangerous situations with the unit Semi skilled staff without the corresponding specialist technical training generally do not have such qualifications and are able to per form these tasks only after instruction and under the supervision of specialist personnel 2 4 Safety information for the user company The superiors of the operating personnel must have understood and must comply with Chapter Safety information and the aspects of operation relevant to safety They must ensure that the operating person nel have understood and follow the safety information Before placing the unit into operation superiors must check that operation of the DOSIPUMP 1000 in con junction with other installations or system sections cannot pose additional risks and dangers If necessary additional technical safety instructions must be drawn up by superiors In order to preclude the possibility of residual risks and dangers the company using the DOSIPUMP 1000 may need to draw up in company instructions and have receipt of these instructions confirmed by the personnel responsible Moreover the
5. You can find a list of all standard accessories and optional accessories in Chapter Techni cal information in Section Accessories 1 3 2 Intended application The DOSIPUMP 1000 is multi function pump 1 3 3 Basic concepts The DOSIPUMP 1000 offers the user a wide variety of functions and features The most important features are outlined in the brief list below Easy to understand user friendly operation with graphic screen and touch screen Variably adjustable sample volumes speed pause time and AntiDrop function Automatic initialisation and self test run The instrument can be calibrated for the relevant tube diameter used The tube fittings can be exchanged easily thanks to the practical lever closure on the pump head Self monitoring of all device functions motors Easy maintenance Optional connection to host PC external printer and footswitch External control with footswitch Page 4 User Manual Version 1 8 DosiPump 1000 User Manual Equipment variants DosiPump 1000 Modes Manual Dispense Item No 7007000 DosiPump 1000 P Modes Manual Dispense Printer Interface RS232 Item No 710 000 DosiPump 1000 PI Modes Manual Dispense Multi Dispense Dilute Item No 720 000 Pipette Interface to host PC and Printer 134 Symbols used in the User Manual The signal words WARNING IMPORTANT and NOTE used in this User Manual serve to highlight im portant information and instructions applicable to dange
6. field is then quit You can switch over between the pages with keys gt lt NUMERIC ENTRIES Name of the entry Description Entry field Value range You can acknowledge the entry and quit the entry field with key Enter OK Page 11 User Manual Version 1 8 DosiPump 1000 User Manual 4 2 Main menu After you switch on the master switch on the rear left hand side DOS TRUE 180680 you will see the DOSIPUMP 1000 main menu after a brief initialisa tion display The software version the time and the current date Q OQO are displayed If a printer 1s connected this 1s also included in the switch on and initialisation routine The printer version is dis 1 42 59 9 JON opp played briefly a MSN ESCH It is possible to branch to three sub menus from the main menu START Actual operating function of the DOSIPUMP 1000 CALIB Calibration of the volume as a function of the tube SYSTEM Allows you to make system settings and presets Touch the displayed keys of the touch screen in order to access the required menu The keys are displayed graphically in such a manner that the key appears to be pressed when you touch it The three sub menus are described in detail in the chapters which follow Page 12 User Manual Version 1 8 DosiPump 1000 User Manual 4 3 Start menu 4 3 1 Overview operating modes The individual operating modes are displayed on screen Func tions Multi Dis
7. key These programs can be selected edited deleted or started with the function keys Keys EDIT and START will now be de scribed 4 3 5 1 EDIT Dilute A program can be edited with the EDIT key DI LUTE LR LN It is important that each program has a name If you press FLOW DILUTER function key NAME you can enter the name on the ES EAE m egenus alphanumeric keypad see 4 1 You can enter a maximum of 12 B 9 2 85 characters Ch The FLOW key allows you to set the pump speed Make the entry with the numeric keypad see 4 1 You can enter a flow rate of 0 1 to 999 9 ml min Key AIR GAP can be used to enter an air gap which separates the two media sample and diluent You can make the entry on the numeric keypad see 4 1 You can enter a value between 0 0 and 9 9 I The SAMPLE key is used to set the volume to be diluted concentrate You can set value between 0 0 ml and 9999 9 ml on the numeric keypad see 4 1 The DILUENT key can be used to set the volume of the diluent You can set a value between 0 1 ml and 9999 9 ml on the numeric keypad see 4 1 ei Key CYCLE PAUSE allows you to set the pause between two cycles with automatic repetition between 0 and 9 9 seconds If you delete the value you must start the next cycle manually with the key or footswitch You can skip one level back with the MENU key You can start the program with the START key Page 20 User Manual Versio
8. the DOSIPUMP 1000 only to a fully earthed mains system in order to avoid electric shock Do not use adapters for plugs and do not remove earthing connections from ca bles If an extension cable has to be used please use only three core cable with correctly earthed plugs 7 Ensure that all cables and tubes are laid in a safe area to prevent the risk of tripping over them 8 Do not spill food or liquids on the DOSIPUMP 1000 Please read the technical guide if the DOSIPUMP 1000 requires cleaning UJ Page 7 User Manual Version 1 8 DosiPump 1000 User Manual 2 7 Warranty and liability The Biotektron company provides warranty for this unit covering defects in relation to both components and design The unit has been thoroughly inspected in order to ensure that it complies with the specifica tions published The Biotektron company guarantees that this unit will remain free of defects for a period of 24 months as of the date of delivery This warranty shall be rendered null and void if the unit is not operated by a trained person in accordance with the instructions supplied by Biotektron or if an unquali fied person attempts to repair the unit 6 NOTE Parts subject to wear are not covered by warranty Page 8 User Manual Version 1 8 DosiPump 1000 User Manual 3 Commissioning 3 1 Unpacking The DOSIPUMP 1000 is supplied packaged in a product specific carton The recommended unpacking pro cedure for the DOSIPUMP 1000 is as follows R
9. user company must stipulate the scopes of authority for working with the 1000 so that there are clear scopes of authority in relation to technical safety aspects 2 5 No arbitrary conversion work or modification work No modifications may be made to the DosIPUMP 1000 In particular defective components may be re placed only by original parts Neither the design nor the technical safety systems of the DosIPUMP 1000 may be modified without our express consent In particular no modifications to safety facilities are per mitted Modifications of any nature will exempt us from liability for resultant damage and injury 2 6 Supplementary safety information 1 The DosIPUMP 1000 may be used only for the intended application as stated and for no other pur poses 2 Maintenance work and repair work may be carried out only by qualified staff The unit must be installed in such a manner that the On Off switch 1s easily accessible at all times 4 Shoulda situation arise in which safe operation of the DOSIPUMP 1000 can no longer be guaranteed the unit must be placed out of operation and locked until it can be repaired by qualified staff Such a situation must be assumed if there 1s visible damage to the DOSIPUMP 1000 the DosIPUMP 1000 is no longer working or the mains circuit over current release trips 5 Disconnect the DOSIPUMP 1000 from the mains power supply before moving it to a new location 6 Connect the power cables of
10. with fuse and master switch Footswitch pin assignment s Pin 1 Footswitch contact 1 1 21 Pin 3 Footswitch contact 2 So 4 Pin 2 29 V The two footswitch contacts are designed as normally open contacts NO 2 PC printer connection pin assignment RS232 Version P PI Pin 1 RxD Pin 2 TxD 1 2 Pin 3 GND Pin 4 VMOT 24 V 29 V for printer only 3 RS485 connector pin assignment Option 2 Pin 1 Internal GND 1 5 Pin 7 Pin 9 Signal GND Do not connect with pin assignments other than those shown above Use only the RS232 Host interface cable original cable as the interface cable to the PC host Connections are provided on the device rear panel depending on options Only the power receptacle 1s provided by default Page 33 User Manual Version 1 8 5 9 Technical data Length Depth Height Net weight Mains connections Mains fuse Dosing quantity Dosing accuracy calibrated tube without AntiDrop Delivery rate Filling cycle delay AntiDrop Display Sound pressure level Pollution severity Safety class Ambient temperature Unit support surface Remote control footswitch Interface RS232 Interface RS485 Stand Item number 200 210 Page 34 DP1000P PI Power DosiPump 1000 User Manual 305 mm 275 mm 205 mm 7 1 kg 85 132 V AC and 176 264 V AC 47 63 Hz 3 15 A 250 V AC slow blow 0 1 9999 9ml one decimal place 0 5 190
11. DISFEHSE function key NAME you can enter the name on the m Tv Io alphanumeric keypad see 4 1 You can enter a maximum of 12 re Se ES RS characters 408 2 85 Ew ANT I DROP H AML The FLOW key allows you to set the pump speed Make the entry with the numeric keypad see 4 1 You can enter a flow rate of 0 1 to 999 9 ml min my The Anti drop key allows the operator to select any retraction angle between 0 90 The Dosipump will execute this Auto reverse of the pump head after each individual dispensed volume in all modes of operation With all consecutive dispensed volumes the pump automatically compensates the selected retraction angle The entry is made with the numeric keypad Values from 0 no Auto reverse up to max 90 are freely selectable The Anti drop is recommended to be used when large port tubes together with high viscous samples do form undesirable drops It increases aseptic contamination free work security It is recommended to se lect smallest possible Auto reverse values The volume to be dosed can be set with VOLUME key You can set dosing volume between 0 1 ml and 9999 9 ml on the numeric keypad see 4 1 E Key CYCLE PAUSE allows you to set the pause between two cycles with automatic repetition between 0 and 9 9 seconds If you delete the value you must start the next cycle manually with the key or footswitch You can skip one level back with the MENU key You can start the pro
12. DOSIPUMP 1000 DosiPump DP1000 DosiPump DP 1000P DosiPump DP 1000P I USER MANUAL 1 8 ENGLISH Part of Thermo Fisher Scientific Page Belgique Belgi Espana France Italia Netherlands Portugal Suisse Switzerland t l 056 260 260 tfno 91515 92 34 t l 03 88 67 53 20 tel 02 953 28 258 tel 020 487 70 00 tel 214253350 t l 05661841 11 User Manual fax fax fax fax fax fax fax 056 260 270 91 5159235 03 88 67 11 68 02 953 27 374 020 487 70 70 21425 3351 056 618 41 41 DosiPump 1000 User Manual be fisher thermofisher com es fisher thermofisher com fr commande thermofisher com it fisher thermofisher com nl info thermofisher com pt fisher thermofisher com info ch thermofisher com www be fishersci com www es fishersci com www fr fishersci com www it fishersci com www nl fishersci com www pt fishersci com www ch fishersci com Version 1 8 DosiPump 1000 User Manual Contents L OY RN eege 3 1 1 PREFACE FURTHER TO THE USER MANUALE 3 1 2 DOSIPUMP MANUAL VERSION 2 ee EE EE Ee 3 1 3 BASIC INFORMATION ON THE DOSIPUMP IO 4 2 SAFETY INFORMATION eene 6 2 1 OPERATING ENNVIRONMENT 6 22 SAFF IY CONSCIOUS WORKING EEN 6 253 QUALIFICATION OF THE OPERATING PERSONNEL 7 2 4 SAFETY INFORMATION FOR THE USER COMDANN
13. ack to the left Immerse the end of the tube intake end into the medium to be dispensed or connect it to the optional culture medium preparation unit U Ne 3 4 Screw on the stand A stand can be fitted with quick fixer to fix the tube fitting in order to make work with the DOSIPUMP 1000 easier 1 Screw the stainless steel stand into the opening on the housing cover 2 Attach the stainless steel cross bar with stand cross clamps 3 Also firmly clamp the quick fixer clamps Page 9 User Manual Version 1 8 DosiPump 1000 User Manual 3 5 Switch the unit on Press the master switch on the rear panel of the DOSIPUMP 1000 The unit is then reinitialised If a printer is connected this printer is also initialised The software version and type are displayed You will see the main menu after initialisation is complete 3 6 Licensing Before the unit can be operated you must first enter the license LICENCE code supplied license sheet The DOSIPUMP 1000 is supplied as standard with a permanent license DUSIPUMP LOCKED Enter license code with the ENTER key PE 51 E The entry must be made alphanumerically and concluded with Enter key OK 1 I 3 K L M N O P AAE 2 9 Ai Switch over between the pages with keys gt lt After license code entry is complete you must then enter the date and time Use the MENU key to comple
14. d to quit the menu Page 26 User Manual Version 1 8 DosiPump 1000 User Manual 4 5 4 Touch The device s touch screen can be calibrated in the Touch menu On delivery the touch screen is already pre calibrated However it may be necessary to recalibrate the touch screen In order to do this touch at the top left hand corner directly You will then PLEASE PRESS ON TOUCH see at the bottom right hand corner This completes the touch screen calibration process and you then quit the menu TOUCH CHLIBRAT IO 4 5 5 Printer The optional log printer can be activated and deactivated in the Printer menu You can press the TEST key in order to test the function of the printer The basic data of the DOSIPUMP 1000 15 PRINT MODE d then printed out Key activates the printer and key deactivates it Pressing the MENU key moves you back to the SYSTEM menu Types of printout test printout license printout log printout 4 5 6 Display You can set the display contrast in the Display menu DISPLAY The contrast can be set to optimum contrast with keys and CONTRAST ADJUSTMENT 4 5 7 About The About menu displays the device specific information 1 The software version with the date of the DOSIPUMP 1000 UEPZIDM NDO 1 7 3 179904 2 The serial number of the devi CERTAL NB O08 G4 BEBE TIME 12 10 2094 18 37 86 3 Current date and time LICENCE ENDLESS 4
15. dy been edited or ongoing in formation such as actual volume status or the cycle counter The cycle counter counts how many times the program has run You can prepare or empty the tube with key MANU see illustration at right Operating mode Program name Basic mode of operation E x4 VOLUME ML P Ob p Flow OR App AN lal mi ACTUAL ML Cycle counter gt cycles a Status gt FEAT External control start Start conti 2 You can also start Manual mode with the 19095 P P dd footswitch at the left The pump doses for Manual Back one menu level as long as the switch is operated Log printout If a printer has been installed and its status is the working log 1s printed out as soon as the program 15 quit Page 15 User Manual Version 1 8 DosiPump 1000 User Manual 4 3 3 Dispense mode Dispense mode doses a preset volume The sample volume the pump speed the AntiDrop function and the program name can be set 10 different program memories are available If you choose an operating mode you can choose between 10 DISPFEHSE customer specific programs You can scroll to the next page with key These programs can be selected edited deleted or started with the function keys Keys EDIT and START will now be de scribed 4 3 3 1 EDIT Dispense A program can be edited with the EDIT key It is important that each program has a name If you press
16. e the tube and run the pump viscous You have used a tube which manually with the PUMP menu is too large Fault signal Pump blocked The selected program has no name Edit the selected program and assign has not been edited it a program name Fault signal No program entered Fault signal License has expired Apply for a new license from the seller with the license application DosiPump barred code and enter the license code No valid license Page 31 User Manual Version 1 8 DosiPump 1000 User Manual 5 6 Accessories Accessory list for the DosiPUMP DP1000 MAINS CABLE GERMAN OR ENGLISH USER GUIDE DOUBLE TUBESET ART 179080 5 7 Options Option list for the DOSIPUMP 1000 FOOTSWITCH PRINTER INTERFACE RS232 DP 1000P PI PRINTER CABLE DP1000P PI RS232 HOST INTERFACE CABLE DP1000PD RS485 BIOLINK INTERFACE DIV TUBE SET S STAINLESS STEEL STAND 200 MM 2012 MM OPTION REST MAT DOSIPUMP COVER Additional operator prompting languages e g French Italian Spanish and Portuguese not provided by default Page 32 User Manual Version 1 8 DosiPump 1000 User Manual 5 8 Electrical connections The connections for the mains power supply and the optional interfaces are located on the right hand side of the DOSIPUMP 1000 rear panel Caption 1 Footswitch Socket DIN41524 5 pin 2 PC printer connection SUB D socket 9 pin 3 RS485 Biolink SUB D socket 9 pin 4 Power receptacle
17. emove the securing straps Open the packaging Remove the inside cover of the packaging Lift the unit out of the packaging Do not grip the unit by the pump head when lifting it out Place the unit onto a sturdy table or bench Remove all miscellaneous packaging items foam rubber and safety stickers and place them back into the transport packaging since they may be needed if it becomes necessary to transport the unit again Se e AN WARNING If there are signs of condensation on the DOSIPUMP 1000 allow at least two hours for the condensation to dry out before switching on or operating the unit 3 2 Mains connection The DOsIPUMP 1000 must be connected to the mains power supply using the enclosed mains cable The electrical connection ratings must correspond to the ratings specified on the sticker on the rear side of the unit and may be neither higher nor lower than these values Connect the power cable of DosiPUMP 1000 only to fully earthed mains power supply system in order to avoid electrical shock Do not use adapters for the plugs and do not remove the earthing connec tions from the cable If it is necessary to use an extension cable please use only three core cables with correctly earthed plugs for this 3 3 Inserting the tube fitting in the pump Perform the following steps to insert the tube fitting in the pump Move the lever on the pump head to the right Insert the tube fitting into the pump Move the lever b
18. ey MANU The bar chart indicates how many different volumes have already been dosed see illustration at right Basic mode of operation Operating mode Program name Target volume AntiDrop Em Actual volume m d EV Sr SE Pause time MELII DISPENSE TEST 1 4 EE Dosing volume gt y Cycle counter status next step Cycle pause Volume counter External control You can also start Multi Dispense mode with the footswitch at the left Start The dosing operation can be cancelled Manual Back one menu level with the footswitch at the right Log printout If a printer has been installed and its status is the working log 1s printed out as soon as the program 15 quit Page 19 User Manual Version 1 8 DosiPump 1000 User Manual 4 3 5 Dilute mode This function allows dilution of a sample concentrate with a downstream diluent Any sample volume can be aspirated and dispensed together with any diluent volume with or without a separation by an air gap You must ensure that the concentrate volume and the diluent volume can be accommodated in the tube canulla or serological pipette The sample quantity the diluent quantity the pump speed the AntiDrop function the air gap and the program name can be freely set 10 different program memories are available If you choose an operating mode you can choose between 10 MULTI DISFEHSE customer specific programs You can scroll to the next page with
19. fic programs You can scroll to the next page with key These programs can be selected edited deleted or started with the function keys Keys EDIT and START will now be de SNE E IX scribed 4341 EDIT Multi Dispense A program can be edited with the EDIT key uw COUNT 8 Dor It is important that each program has a name If you press SHEETS Dx ovguerause function key NAME you can enter the name on the Eu eae alphanumeric keypad see 4 1 You can enter a maximum of 12 characters The FLOW key allows you to set the pump speed Make the ES HEEN entry with the numeric keypad see 4 1 You can enter a goa flow rate of 0 1 to 999 9 ml min Bau VOLUME 6 T The Anti drop key allows the operator to select any retrac tion angle between 0 90 The Dosipump will execute this Auto reverse of the pump head after each individual dispensed volume in all modes of operation With all consecutive dispensed volumes the pump automatically compensates the selected retraction angle The entry is made with the numeric keypad Values from 0 no Auto reverse up to max 90 are freely selectable The Anti drop is recommended to be used when large port tubes together with high viscous samples do form undesirable drops It increases aseptic contamination free work security It is recommended to se lect smallest possible Auto reverse values tJ Key COUNT can be used to set the number of different volumes This coun
20. gram with the START key Page 16 User Manual Version 1 8 DosiPump 1000 User Manual 4 3 3 2 START Dispense The Start window contains a wide variety of information which has already been edited or ongoing in formation such as actual volume status or the cycle counter The cycle counter counts how many times a program has run You can prepare or empty the tube with key MANU see illustration at right Target volume Basic mode of operation Operating Program name Actual volume mode SS 8 3 AntiDrop VOLUME ML VW Flow SE 2 8 Dosing volume priiis SAPS ACTUAL ML Cycle pause CYCLES 8 External control Cycle counter Ga Status You can also start Dispense mode with the footswitch at the left The dosing Start wee Dad operation can be cancelled with the foot switch at the right Manual Back one menu level Log printout If a printer has been installed and its status is on the working log is printed out as soon as the program is quit Page 17 User Manual Version 1 8 DosiPump 1000 User Manual 4 3 4 Multi Dispense mode Up to 12 different volumes can be processed consecutively in Multi Dispense mode Twelve individual pump volumes the pump speed the AntiDrop function a pause time between dosing operations and the program name can be set 10 different program memories are available MULTI DISPENSE ul If you choose an operating mode you can choose between 10 customer speci
21. l of the unit should be near to the front edge of the workbench in order to ensure convenient operation and easy access to the touch screen The unit should be installed in the direct vicinity of electrical socket outlets Summary of the DOSIPUMP 1000 operating environment Temperature range 5 C to 45 C Relative humidity Max 80 up to 31 C decreasing in linear fashion down to 50 at 40 C Mains power supply Voltage fluctuations 10 of rated value Pollution severity 2 in accordance with IEC 664 Location Complying with enclosure IP 21 Sturdy support surface Environment Avoid splash water and contact with chemicals There must be no risk of explosion AN WARNING We are unable to guarantee operability and functional safety of the unit if the ambient conditions applicable to the location are not complied with 2 2 Safety conscious working The DosiPuMP 1000 complies with state of the art and is safe to operate The DOSIPUMP 1000 may pose residual risks and dangers if it 15 used and operated incorrectly by untrained personnel All persons entrusted with the task of operating the DOSIPUMP 1000 must have read and understood the User Manual and in particular the safety information or must have been instructed by superiors in such a manner that they are able to safely operate the DOSIPUMP 1000 Besides the safety information listed above other applicable provisions and regulations such as GLP GMP FDA the regulations of the
22. lains the mode of operation and the operating procedures for the DOSIPUMP 1000 The User Manual is subdivided into five main sections 1 Overview 2 Safety information 3 Commissioning 4 Operation of the DOSIPUMP 1000 5 Technical information Each section consists of a guide to the individual functions structured step by step The user is also pro vided with special information relating directly to the relevant task explained Warning Important and Note Overview The Overview contains general information on the DOSIPUMP 1000 the intended application and the basic concept Safety information The DOSIPUMP 1000 safety information Commissioning The steps and preparatory work required for commissioning Operation of the DOSIPUMP 1000 This section documents all information required for daily operation It explains both operation and all parameters Technical information This section provides comprehensive technical information on all functions of the DOSIPUMP 1000 This section is structured so that it can be used both as a source of additional useful information on operation and as an independent reference work 1 2 Dosipump Manual Version 1 2 Dosipump Software Version V 1 8 15 09 06 New Mode Function Antidrop New Mode Dilute Page 3 User Manual Version 1 8 DosiPump 1000 User Manual 1 3 Basic information on the DOSIPUMP 1000 1 3 1 Introduction to the DOSIPUMP 1000 Figure 1 DOSIPUMP 1000 Note
23. n 1 8 DosiPump 1000 User Manual 4 3 5 2 START Dilute The Start window contains a wide variety of information which has already been edited or ongoing in formation such as actual volume status or the cycle counter The cycle counter counts how many times a program has run You can prepare or empty the tube with key MANU see illustration at right Basic mode of operation Operating mode Program name Target volume B Actual volume da Air gap LI g Flow 1 Air Pause 2 Sample 3 Dispense w Diluent Sample volume 5 Cycle counter External control plas Dilute You can also start the Dilute mode with pause p the footswitch at the left The dosing Start Nod operation can be cancelled with the foot Manual Back one menu level switch at the right Log printout If a printer has been installed and its status is the working log 15 printed out as soon as the program 15 quit Page 21 User Manual Version 1 8 DosiPump 1000 User Manual 4 3 6 Pipette mode This function allows the aspiration and dispensation of any defined volume The sample volume the pump speed and the program name can be set 10 different program memories are available If you choose an operating mode you can choose between 10 PIPETTE customer specific programs You can scroll to the next page with key These programs can be selected edited deleted or started with the function ke
24. nly with water or soapy water Never remove residue by scratching or scraping the touch screen m IMPORTANT Never use too much water since this could otherwise result in water entering the unit Never remove residue by scratching or scraping Page 28 User Manual Version 1 8 DosiPump 1000 User Manual 5 3 Transporting the DOSIPUMP 1000 m IMPORTANT Remove all tubes and disconnect the unit from the mains power supply be fore moving the unit m IMPORTANT When moving the unit always grip it at the bottom and not on the pump head 5 4 Calibration Corporate guidelines prescribe that all companies operating with a quality assurance system must regu larly calibrate their instruments and equipment Calibration must ensure that the unit complies with the stipulated specifications When should calibration be carried out Calibration relates to the dosing volume of the pump as a function of the tube You are advised to cali brate the pump at the following times e After changing a tube fitting e If using culture media with greatly differing viscosities e At regular intervals e g every 3 months 6 NOTE The calibration procedure is described in Chapter Calibration menu Page 29 User Manual Version 1 8 DosiPump 1000 User Manual 5 5 Troubleshooting 5 5 1 Overview The DOSIPUMP 1000 software incorporates troubleshooting routines which be used to correct certain problems without action on the part of after sales se
25. operation Operating mode Program name Target volume ep ih SCH MON volume Sample volume DOSIOI GENE OW a MEI mi VOLUME ML Flow ana on H Cycle pause ACTUAL ML Cycle counter CYCLES H External control Status PREATY You can also start Pipette mode with the footswitch at the left The dosing opera SR tion can be cancelled with the footswitch Start aad yee at the right Manual Back one menu level Log printout If a printer has been installed and its status is the working log 1s printed out as soon as the program 15 quit Page 23 User Manual Version 1 8 DosiPump 1000 User Manual 4 4 Calibration menu It is advisable to adapt calibration to the application The pump accuracy depends on the speed and the tube diameter 4 4 1 Overview Calibration is performed with the seven keys FLIMP COLIBEATION Start Disp Manual Volume Speed and Menu CHLIFRHTION VOLUME w PUMP VOLUME ML AH LAM d SPEED TO START CALIBRATITON PRESS STHRT 44 2 Description of the key functions VOLUME You can set the pump volume to be calibrated CAL UDLLIME ith the VOLUME key ias 7 PUMPED VOLUME E You can complete and save the entry with the Enter key 100 6 n e AL Speed You can set the speed pump speed at which calibration is to be performed with the SPEED k REVOLUTION AT ey CALIBRATION You can complete and save the entry with the Enter ke
26. pense Dilute and Pipette may not be supported depending on pump type MULTI DosiPump 1000 P Manual Dispense ET ode DosiPump 1000 PI Manual Dispense Multi Dispense This menu allows two to five different operating functions MANUAL Manual mode is the simplest operating function The pump is operated manually with Start and Stop DISPENSE Dispense mode dispenses a preset volume MULTI Multi Dispense mode allows you to process up to 12 different volumes DISPENSE consecutively DILUTE This function allows dilution of a sample concentrate with a downstream diluent PIPETTE The function allows pipetting of a volume This means that a specific volume can be inducted This volume is then issued again including a reserve MENU This menu allows you to return to the main menu Touch the displayed keys of the touch screen in order to access the required menu The keys are displayed graphically in such a manner that the key appears to be pressed when you touch it Page 13 User Manual Version 1 8 DosiPump 1000 User Manual 4 3 2 Manual mode Manual mode is the simplest operating function The pump speed the AntiDrop function and a program name can be set Ten different program memories are available If you select an operating mode you can choose between 10 HMEHNLIEBIL customer specific programs You can scroll to the next page with key These programs can be selected edited deleted o
27. r situations These words can be found together with a special warning symbol in the left hand column Symbol Definition Warning points out a potentially dangerous situation which should be avoided in order to avoid damage to the equipment or injuries This signal word is used only in extreme situations and thus requires special attention Important points out special problems or important information Please read through the m accompanying text carefully It 1s important for understanding the relevant topic or command Note serves to identify information which is useful but not crucial to a task Read 6 though accompanying text carefully It may help you to clarify any questions which you may have Table 1 Caption to the symbols Page 5 User Manual Version 1 8 DosiPump 1000 User Manual 2 Safety information 2 1 Operating environment Several factors must be noted when selecting the right operating environment for the unit The room se lected may not pose an aggressive environment either for the unit itself or for its intended application The DosiPUMP 1000 should be operated only under ambient conditions corresponding to a normal envi ronment 5 C with maximum 80 relative humidity The relative humidity must decrease in linear fash ion with a rise in temperature 6 NOTE These conditions also apply to transport The DOSIPUMP 1000 should be installed on a clean dry smooth horizontal surface The front pane
28. r started with the function keys Keys EDIT and START will now be de scribed 4 3 2 1 Manual EDIT A program can be edited with the EDIT key MANUAL It is important that each program has a name If you press Ta Goen function key NAME you can enter the name on the Vd HIP alphanumeric keypad see 4 1 A maximum of 12 characters can EU E a be entered The FLOW key allows you to set the pump speed Make entry with numeric keypad see 4 1 You can enter a flow rate of between 0 1 and 999 9 ml min T The Anti drop key allows the operator to select any retraction angle between 0 90 The Dosipump will execute this Auto reverse of the pump head after each individual dispensed volume in all modes of operation With all consecutive dispensed volumes the pump automatically compensates the selected retraction angle The entry is made with the numeric keypad Values from 0 no Auto reverse up to max 90 are freely selectable The Anti drop is recommended to be used when large port tubes together with high viscous samples do form undesirable drops It increases aseptic contamination free work security It is recommended to se lect smallest possible Auto reverse values You can skip one level back with the MENU key You can start the program with the START key Page 14 User Manual Version 1 8 DosiPump 1000 User Manual 43 22 Manual START The Start window contains a wide variety of information which has alrea
29. rvicing technicians If a problem occurs on the DOSIPUMP 1000 the unit attempts to correct the problem by providing the op erator with prompts on the graphical user interface If these on screen prompts are followed the fault or error can then normally be remedied without action on the part of after sales servicing technicians Each error message with alarm function also contains a description of the fault or error 5 5 2 Fault clearance The table below can be used to help you to remedy certain problems which may occur during operation of the DosIPUMP 1000 This table contains information on the symptom its possible causes and the remedial action for the relevant fault or error involved Errors which occur before operation Symptom Correction Device does not start Plug not plugged in Check power connection Master switch not switched on Switch on Master switch fuse defective Check fuse See details of description Check power connection No mains power Replacing the device fuse In order to replace the device fuse use a small screwdriver to lever the fuse holder of the power receptacle down and out Fuse 3 15 A 250 V AC slow blow No fuses with other ratings may be used A WARNING Always disconnect the mains cable first before replacing the fuse Page 30 User Manual Version 1 8 DosiPump 1000 User Manual Faults and errors occurring during operation Symptom Correction The culture medium in the tube is too Remov
30. t then enables the en tered volumes You can set the count between 1 and 12 on the numeric keypad see 4 1 x A pause between dosing of the individual volumes can be set MULTI DISPENSE with the PAUSE key You can set the pause time between EH EI 0 0 and 9 9 seconds on the numeric keypad see 4 1 If the pause a Jotun 1 is set to 0 seconds you must start manually after each dosing operation Otherwise the various volumes will be dosed CN kee End ge automatically with the set pause time Page 18 User Manual Version 1 8 DosiPump 1000 User Manual Key CYCLE PAUSE allows you to set the pause between two cycles with automatic repetition between 0 and 9 9 seconds If you delete the value you must start the next cycle manually with the key or footswitch The volumes to be dosed are set with keys VOLUMES 1 12 You can set dosing volumes be tween 0 1 ml and 9999 9 ml on the numeric keypad see 4 1 If the count is set to 5 for instance the volume values of 6 12 are not displayed You can skip one level back with the MENU key You can start the program with the START key You can scroll to the next page with key 4 3 4 2 START Multi Dispense The Start window contains a wide variety of information which has already been edited or ongoing in formation such as actual volume status or the cycle counter The cycle counter counts how many times a program has run You can prepare or empty the tube with k
31. te the entry after which the unit is ready for operation If a unit is used for test purposes for instance the unit may be activated by the seller for a specific period time limited license The License window with the application code is displayed on screen after this period elapses You can use this code to apply for a new license from the seller You can print out the application code with the key Use key ENTER to enter the license code Page 10 User Manual Version 1 8 DosiPump 1000 User Manual 4 Operation of the DOSIPUMP 1000 4 Fundamentals significance of the symbols Program text Flow rate Culture medium filling quantity volume AntiDrop function for preventing drips Pump menu Pause time after filling Pump menu Number of volumes in the case of Multi Dispense DG e Air gap between diluent and sample Diluent Status for external logging software DOSIPUMP Recorder This symbol is displayed in the top right hand corner of the screen as soon as the software has been launched and communication has been established with the DOSIPUMP 1000 E Cycle pause between two cycles with automatic repetition ALPHANUMERIC ENTRIES Alphanumeric entries are used for the program name or license SL PHONUM de a displayed in th d b DEER t Is di int t PRS is displayed in the upper sector and can DRBGEGE The entry can be acknowledged with key Enter OK after which the entry
32. u In S S TEM addition detailed information on the software versions can be retrieved in this menu 3 nae care tte TOUCH The System menu consists of six sub menus SCH 1 Language Selects the national language SELECT 2 Date Time Sets the date and time 3 Touch Calibration of the touch screen 4 Printer Activates and deactivates the printer function 5 Display Display contrast setting 6 About Information about the DOSIPUMP 1000 4 5 2 Language The user can set his or her required language in the Language LANGUAGE menu Chose the required language with the CONTINUE key The se lected language becomes the current language immediately on advancing with the CONTINUE key If you touch the MENU key the selected language remains saved even after a restart of the DOSIPUMP 1000 4 5 3 Date and Time The device time and the device date can be set in the Date and DATE TIME Time menu The date and time are required for any log printout The date and time can be disabled by the license generator This le BI s 21 disable function is used to prevent the date being reset thus by 11 OCT 2904 passing the licensing process Choose the required field with the CONTINUE key The time is set in format Hours Minutes Seconds in the first line and the date is set in format Day Month Year in the second line The entries directly update the current time Keys and are used to change the values and key MENU is use
33. y MENU You can switch back to the main menu with the MENU key Page 24 User Manual Version 1 8 START DISP MANUAL Page 25 DosiPump 1000 User Manual You can start calibration with the START key FUMF CHL I BEHT I OH However you should have set the calibration pa rameters beforehand PLEASE INSERT TUBE IN PUMP After starting calibration the user is prompted to HND MEHSURING CUP insert the tube into the pump and measuring beaker 2 r sr D doo ev The calibration volume is dispensed into the meas CALIBFAT ION uring beaker after restart CHLIERHTION VOLUME BOTTLE After completion of pumping the pumped volume must be measured e g with measuring beaker or FLEASE ENTER scales and the result must be entered on the nu MEASUREMENT VOLUME meric keypad Pressing key Enter completes pump calibration and saves results Hil 9999 9 The calibrated pump volume is taken as the basis for all volume and speed changes after calibration It is advisable to also recalibrate the tube after speed changes Using the DISP key you can check whether the volume is being dispensed precisely after calibration is complete You can abort this with the STOP key You can use key MANUAL to induct the medium or empty the tube User Manual Version 1 8 DosiPump 1000 User Manual 4 5 System menu 451 Overview The system wide settings and presets are made in this men
34. ys Keys EDIT and START will now be de scribed 4 3 6 1 EDIT Pipette PIPETTE A program can be edited with the EDIT key m BER Va ees FLOW It is important that each program has a name If you press Elon function key NAME you can enter the name on the alphanumeric keypad see 4 1 You can enter a maximum of 12 characters The FLOW key allows you to set the pump speed Make entry with numeric keypad see 4 1 You can enter a flow rate of 0 1 to 999 9 ml min ui The SAMPLE key is used to set the volume to be pipetted You can set a value between 0 0 ml and 9999 9 ml on the numeric keypad see 4 1 ei Key CYCLE PAUSE allows you to set the pause between two cycles with automatic repetition between 0 and 9 9 seconds If you delete the value you must start the next cycle manually with the key or footswitch m IMPORTANT The set value of the sample must be able to be accommodated in the tube canulla or serological pipette You can skip one level back with the MENU key You can start the program with the START key Page 22 User Manual Version 1 8 DosiPump 1000 User Manual 4 3 6 2 START Pipette The Start window contains a wide variety of information which has already been edited or ongoing in formation such as actual volume status or the cycle counter The cycle counter counts how many times a program has run You can prepare or empty the tube with key MANU see illustration at right Basic mode of
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