Home
ILab 300 Plus Service Manual
Contents
1. is E K K ae KKK 2 ON EVI empitying of the channel of the Probel is enabled uP4 ON uPump Probe5 0 ON peristaltic pump remains ON until the end of the cycle Washing Station goes down 570115 Liquid into the cuvette is aspirated Aspirated and dispenced 400uL 50uL of Dist Water While empitying with the Peristaltic Pump Wait 100mS Aspirated and dispenced 400uL 50uL of Dist Water While empitying with the Peristaltic Pump Wait 100mS Aspirated and dispenced 400uL 50uL of Dist Water While empitying with the Peristaltic Pump Wait 300mS Washing Station goes up 570mS OFF EVI empitying of the channel of Probel is disabled uP4 OFF uPump Probe5 OFF Pump peristaltic Cycle lasts 3790mS used 1200ul 150ul of Dist Water ie of oe os of 565255503235 of oe of oft ae of oft oe oe ae oft oe ae of oie ae of oe a of oe a ok a ok Probe 3 ON EVI empitying of the channel of the Probel is enabled uP4 ON uPump Probe5 0 ON peristaltic pump remains ON until the end of the cycle Washing Station goes down 570115 ON EVS filling of the channel of the Probe3 is enabled Erogo 400uL 50uL of Dist Water Washing Station goes up 570mS OFF EVI empitying of the channel of the Probel is disabled uP4 OFF uPump Probe5 0 OFF Pump peristaltic EV5 filling
2. REACTION CHAMBER MOTOR INTERFACE BOARD FROM DRIVERS BOARD 00188 01 1 FILTER WHEEL MOTOR WASH STATION MOTOR REACTION PLATE CUVETTE HOLDER FROM POWER SUPPLY WASH STATION MOTOR OPTICAL CUVETTE HOLDER REACTION TRAY Saee gu 45 anya 4 j D L 47 esr DA Sy 9 ZZ OPTICAL SENSOR CUVETTE HOLDER OPTICAL SENSOR WASH STATION COIL CUVETTE HOLDER HEATER OPTICAL SENSOR FILTER WHEEL FROM U CONTROLLER 00195 01 9 OPTICAL SENSOR REACTION PLATE TO LAMP POWER ASSY TO NIC SENSOR TO REF CH PHOTOMETER TO SAMPLE CH PHOTOMETER PHOTOMETER ASSY OFFSET GAIN O Emission PHOTOMETER LAMP LAMP PWS REACTION TRAY SENSOR ADJUSTMENT Description Checked Date Approved Date The present drawing is property of AMS any use without Analyzer authorization will be prosecuted accordingly to the law Via Forlanini te 10 12 2001 Medical Tiburtina
3. 2 4 20 ANALYTICAL VERIFICATION 265g 20 SWITCH OFF THE INSTRUMENT inr repehner ERE 2l ILab 300 Plus Service Manual Rev 03 January 2004 Page 1 7 MAINTENANCE Chapter 07 Mantenance This chapter contains all those routine operations which concern instrument maintenance Said procedures listed and described below should be carefully and scrupulously followed in order to guarantee the manufacturer s specifications and the perfect working order of the instrument over time 71 PREVENTIVE MAINTENANCE MAINTENANCE SCHEDULE Table A illustrated below lists all those procedures to be carried out by the user operator and the relative frequency schedule Strict adherence to said schedule will guarantee the optimal operative efficiency of the instrument TABLE A MAINTENANCE SCHEDULE FREQUENCY PROCEDURE NOTES DAILY Before launching Start Work Check the levels of all the wash solutions Rinse Water Cleaning DAILY Before launching Start Work Check the levels of Reagents Standards and Controls DAILY Before launching Start Work Check the levels of the Waste Bottles and if necessary empty them DAILY Before launching Start Work Carry out a WBL cycle See the User s Manual Chapter 03 Description of Instrument Software DAILY After Shutdown Clean the Sampling Probe using either paper to
4. 27 ILab 300 Plus Service Manual Rev 04 January 2004 Page 1 6 1 6 3 6 1 6 4 6 16 5 6 2 6 2 1 6 2 2 6 2 3 6 2 4 6 2 5 6 2 6 6 3 6 3 1 6 3 2 6 3 2 1 6 3 3 6 3 4 6 3 4 1 6 4 6 4 1 6 4 2 6 4 3 6 4 4 6 5 6 5 1 Chapter 06 SETTINGS AND ADJUSTMENTS SUBSTITUTION OF THE DILUTER ELECTRO VALVE 28 DILUTER MODULE CHECK PROCEDURE FOR MECHANICAL FUNCTIONING tbi it pot ord MS bm cep Ud A tud d pipi Monee 28 BACKLASH ADJUSTMENT 222 550 r anta Rea E haya nn 29 SSSENIBD Ras DE RE D eua qud ute 3l SUBSTITUTION OPTIC ASSEMBLY bs een esae inea ea equa 3l SUBSTITUTION OF THE PHOTOMETER LAMP eee 33 ELECTRONIC ADJUSTMENT OF THE PHOTOMETER eee 34 SUBSTITUTION OF THE SENSOR rep repr sine 36 SUBSTITUTION OF THE MO TORS 37 SUBSTITUTION OF THE OPTIC FILTERS ettet tette ina 38 PUMP ASSEMBLY teste eae 39 SUBSTITUTION OF THE PUMP ASSEMBLY eaae 39 SUBSTITUTION OF THE PERISTALTIC PUMP MOTOR 40 FUNCTION CHECK FOR THE PERISTALTIC PUMP eee 41 SUBSTITUTION OF
5. 805 TO220 V OUT J9 J10 ST BY AUDIBLE R13 R15 ALARM OFF 750R 750R 76384 304 J8 READY R7 750R m ii WN AUN 76384 304 LS1 BUZZER KSMP MICS D 26 MP2 76384 305 J2 J4 J5 J6 SAMPLE RINSE D WATER CLEANING COVER BOTTLE BOTTLE SOL R24 BOTTLE 10K 1 H 3 76384 302 76384 303 76384 303 76384 303 76384 303 R6 50K J13 Mou RQ AOK NTC 2 6 AN1 1 76384 302 LMC7101 R12 10K 2 0 Emission Rev Description Checked Approved Approved Analyzer EP Medical S Checked ystem R CORNACCHIA itle CONTROL PANEL ize Document Number MA 00342 00 The present drawing is property of AMS any use without authorization will be prosecuted accordingly to the law Date Monday June 04 2001 Sheet 1 of 1 5 Sn INE E3 0 AMS P N 38 08342 M Emission Description Checked Approved The present drawing is property of AMS any use without Analyzer Via Forlanini s n c authorization will be prosecuted accordingly to the law Medical Tiburtina km 18 300 uidonia Roma Drawn Date EE A Nicoletti 08 06 2001 Description Scale Sheet Checked Date CONTROL PANEL 0808 200 Car Drawing Rev Approved Date 00342 00 08 06 2001
6. eere 5 3 4 COMPUTER INSTRUMENT 22 22 0 0 404004 00000000000 0 5 3 5 LABLES 5 2 20 2 6 6 3 6 INSTALLATION 0 0 00004 7 3 6 1 Software Installation 0 22 2 0 04 2 9 3 7 FIRMWARE AND MASTER HARDWARE UPGRADING cece eee eee 11 3 8 ANALYTICAL 1 1141 442 2 13 Service Manual March 2003 Rev 01 Page 1 Chapter 03 INSTALLATION CHAPTER 03 INSTALLATION INDEX Sl UNPACKINGS i ei ooi tar Gap DR SORORIS OR 2 3 2 INSTALLATION cause S exa R gun da oe auo nt ame e AE 4 3 2 1 INSTALLATION SITE SPECIFICATIONS eret ed vereda 4 3 2 2 ELECTRIC CURRENT 2 22 222 4 3 2 3 CONNECTION OF THE ACCESSORIES eter ie dade ads decades 5 3431 POWER SUPPE Y iie ctt on SEE Hte E neben mE Ex 5 3 2 3 2 COMPUTER INSTRUMENT CONNEC TION 5 Sc ATTENTION Mata 6 EiRicadulig Pm 6 3 20 REGULATORY COMPLIANCE 6 3 3 INSTALLATION ACTIVITY
7. FOLDER 5 3 1 VERTICAL COMMAND AREA 5 3 2 HORIZONTAL COMMAND AREA 5 3 3 STATUS COMMAND AREA 5 3 4 ARM SETTING COMMAND AREA 5 4 DILUTER FOLDER 5 4 1 OPERATIONS AREA 5 4 2 SENSOR STATE AREA 5 4 3 USER AREA 5 4 4 STATUS COMMAND AREA 5 5 OPTIC FOLDER 5 5 1 OPERATIONS AREA 5 5 2 SENSOR STATE AREA 5 5 3 FILTERS AREA 5 5 4 DIGITAL CONVERSION AREA 5 5 5 STATUS COMMAND AREA 5 6 PLATE FOLDER 5 6 OPERATIONS AREA 5 6 2 SENSOR STATE AREA 5 6 3 USER AREA 5 6 4 MOTOR ON OFF AREA 5 6 5 REACTION PLATE AREA 5 6 6 STATUS COMMAND AREA ILab 300 Plus Service Manual Rev 02 January 2004 N 10 10 11 11 12 13 13 13 13 14 15 15 15 16 16 17 18 18 18 18 18 18 1 Chapter 05 DIAGNOSTIC PROGRAM 5 7 TEMPERATURES FOLDER 5 7 1 TEMPERATURES AREA 5 7 2 OFFSET AREA 5 7 3 TEMPERATURE TEST AREA 5 7 4 STATUS COMMAND AREA 5 8 WASH FOLDER 5 8 1 OPERATIONS AREA 5 8 2 SENSOR STATUS AREA 5 8 5 TEST AREA 5 8 4 STATUS COMMAND AREA 5 8 5 SENSOR STATE 5 9 USER FOLDER 5 9 1 USER TEST MICRO 1 AREA 5 9 2 USER TEST MICRO 2 AREA 5 9 3 STATUS COMMAND AREA 5 10 MISCELLANEOUS FOLDER 5 10 1 GENERAL RESET AREA 5 10 2 SENSOR CHECKING AREA 5 10 3 LOG RAW DATA AREA 5 10 4 CONTINUOUS TEST RUN 5 10 5 SENSOR STATUS AREA 5 10 6 STATUS COMMAND AREA 5 11 GLOBAL SETTING FOLDER 5 11 1 TABLE POSITION 5 11 2 KEYBOARD 5 11 3 DOWN ARM 5 11 4 SETTING OF 5 12 MACRO SETTING FOLDER 5 13 CONFIGURATION F
8. tede nu eO ee eiie eu edo dtes 7 3 4 SOFTWARE INSTALLATION 2 02040 9 3 3 55 e 11 ILab 300 Plus Service Manual Rev 02 January 2004 Page 1 Chapter 03 INSTALLATION 3 1 UNPACKING The ILAB 300 PLUS is packed and delivered in two separate wooden crates one contains the analyzer itself and the other the computer along with its accessories In the event that the order not include the PC component packing and delivery will involve one wooden crate plus a corrugated cardboard box The packing has been expressly studied and designed to insure maximum protection of the contents during shipping and handling It is therefore extremely important that the crate s box be carefully examined upon delivery in order to ascertain their integrity Special attention should be dedicated to examining the color of the Shock Watch glued to the crates which must show the color white A red Shock Watch indicates that the crate s have experienced some sort of shock during handling transport and or delivery This fact must be noted by the courier on the delivery note as must any and all visible external damage for example holes dents rips or tears water marks etc evident at the moment of delivery This will simpli
9. 41 MECHANICAL ADJUSTMENT OF THE PERISTALTIC 42 HOW TO SUBSTITUTE PERISTALTIC PUMP TUBES 43 REACTION PLA VE 44 REACTION PLATE MECHANICAL 2 2222 44 SUBSTITUTION OF THE REACTION 1 45 SUBSTITUTION OF THE OS3 OPTIC SENSOR eese 46 SUBSTITUTION OF THE M3 MOTOR ia tub e e IO Ceres 48 WASHING STATION ASSEMBLY ee eas 50 SUBSTITUTION OF THE WASHING STATION ASSEMBLY 50 ILab 300 Plus Service Manual Rev 04 January 2004 Page 2 6 5 2 6 5 3 6 5 4 6 5 4 1 6 5 4 2 6 5 4 3 6 5 5 6 5 5 1 6 5 5 2 6 5 5 3 6 6 6 6 1 6 6 2 6 6 3 6 7 6 7 1 6 7 2 Chapter 06 SETTINGS AND ADJUSTMENTS SUBSTITUTION OF THE WASHING STATION OPTIC SENSOR 52 SUBSTITUTION OF THE WASHING STATION 52 WASHING STATION MECHANICAL ADJUSTMENT AND FUNCTIONAL atit a RARI LN A epe MR qu ud 53 WASHING STATION HORIZONTAL ALIGNMENT esee 53 WASHING STATION VERTICAL ALIGNMENT eee 54 WASHING STATION FUNCTIONAL CHECK 54 WASHING STATION CUVETTE HOLDER ASSEM
10. N N c 5 GIG _ NIN C Ci I E NS 5 ei N W Ee es mms m BR NIN NIN N N FEE m m 013 o o o o o o o o o o o o o o o o o o o o o o ILab 300 Plus Service Manual March 2003 Rev 01 Page 12 Chapter 2 GENERAL DESCRIPTION Peristaltic pump B sense 118 16 RINPI2 18 14 RINPI3 RS232 TX R92IN Auxiliary RX 4 4 18 26 14 6 JI 145 RPWM T1024 Micro R address 2 data ready J10 15 ADCI data ready 1 1 1 U6 47 ROSR2_ Notused _ 0 6 12 16 718 12 4 118 15 13 1 13 3 110 110 6 110 2 X93 RS232 RX N N N O m N 20 20 5 UN o0 PIPIPIPIP PIP JP va 25 17 22 12 18 22 18 g 9 g ES 2 D E 2 E 2 5 gt 3 H oo lt A D U24B 510 16 U20 olo E gt l R71 R73 R75 R76 R81 R82 R83 13
11. 18 300 DW 00012 Guidonia Roma System A Nicoletti 3 Da Description Scale Sheet Checked Date REACTION CHAMBER ASSY Drawing Rev Approved Date NOZZLE NOZZLE NOZZLE NOZZLE NOZZLE NOZZLE Normally open Comm Normally closed N C Normally closed valve TO WASTE 1 1st CH TO WASTE 2 2st CH 1 CL SOL DISPENSE 5 DIST WATER DISPENSE 2 DIST WATER DISPENSE 4 ASPIRATION 2 ASPIRATION 1 ASPIRATION Ar UNS BER Ae FROM CL SOL FROM DIST WATER RESERVOIR FROM PROBE WASH WELL TO WASTE 3 FROM CUVETTE DRIER NOZZLE 5 Emission The present drawing is property of AMS any use without Analyzer Va authorization will be prosecuted accordingly to the low Medical 18 300 Drown 00012 Guidonia Roma Description u2 hec WASHING STATION PUMPS __ of 1 A Gagliarducei liarducci 50 11 2001 11 2001 ae 0406 00 Approved 0406 00 00 0406 00 AGagliarducci 5 20 11 2001 11 2001 REAC CHAMBER MOT INTERF TO REAC CHAMB INTERF BOARD 00341 00 J1 00193 01 J1 FROM POWER SUPPLY TO SAMP ASSY INTERFACE 00192 01 J2 TO SAMP ASSY INTERF 0192 017315 TO SAMP ASSY INTERF 0192 01 J1 TO PERIST PUMP WASH STATION FROM POWER SUPPLY J3 TO CONTR PANEL J1 d J13 J14 il 5 00342 00 J1 TO EXT 26
12. Air in Cal B 1 Insufficient Cal B pipped a Host Instrument must into module sample port deliver 70 wl Increase dispensed volume Insufficient sample in sample cup for all tests programmed 2 Sample not positioned a Pumps not connected properly properly Pump tubing obstructed or tubing length is excessive for spring and seal reported for Sample or Cal B new one and recalibrate 3 Cal A pump is not working a Check electrical properly connections b Replace pump cassette c Replace motor 4 Tubing is plugged split or Replace tubing crimpted ILab 300 Plus Service Manual Rev 02 January 2004 Page 14 Chapter 13 Spare Parts List Chapter 13 Spare Parts This chapter contains the part lists for all the servicing aids and replaceable parts for all the ILab 300 Plus systems For easier identification of the parts this section includes the following documentation List Sorted by IL Part Number Pag 2 List Sorted by Description Pag 5 ILab 300 Plus Service Manual January 2004 Rev 02 I ILab 300 Plus LL Part Number 23010120100 23010122400 23050040300 23050040400 23050040500 23050041300 23050044700 23050045901 23050051900 23050052000 23100010800 23100020201 23100028601 23100039900 23135000500 23300010700 23300010703 23300010705 23300018801 23300019201 23300019301 23300019501 23300034100 23300034200 23300041900 23300044600 23350049300 23350076100 23350081400 23350081500
13. N 8 15 0019 00 QPTIQNAL REACTIDN TRAY INTERFACE 30 00103 01 30 00192 01 REAC CHAMBER MOTOR INTERFACE CONTROL PANEL 20 00342 D0 MT 4 Cover lock OPTIONAL switch The present drawing property of ANS woe without Analyzer Vie Forlenini authorization will be prosmcuted accordingly the low EIRE s a PNTINTERCONNECTION DIAGRAM 74 140 COLLECAMENTI d T J1 14 4 2 01 15 4 3 31 12 44 6 J1 7 44 51 41 7 50 00356 00 14 _ wig S Pin 1 Emission Description Checked Date Approved Date NOTA Le targhette Rif 7 e 8 devono essere bianche Analyzer Lou scu VO E QUEE TL NI REA Vis Farleniai authorization will be prosecuted accordingly to the law e stampate con inchiostro nero e caratteri alti 2mm Medical Ure Tura im 18200 Description Scale Sheet Checked Pete CAVO ALIMENTAZIONE Drawing Rev Approved Date 50 00356 00 A Gagliarducci 18 07 2001 ingr rete Input line 9 10 0014 00 _ RTN12 5V RTN12 5V RTN12 5V 1 2 9 12 10 11 Power supply 9 355 0034 02 WU Ass alimentatore Power supply assy 9 15 0014 01 Emission The present draw
14. eral Esc lock lock lock Num Lock Fig 6 Close External rm Raise Probe 8 1 Zra CCW Rotation 1 Next Position 4 Open External R EE Ex Exitfrom Setting 31 Exit Operations PeDn Lower Probe ILab 300 Plus Service Manual Rev 02 January 2004 Page 29 Chapter 05 DIAGNOSTIC PROGRAM 5 11 5 DOWN ARM This area has the option to decide if the arm once set in a determined position should automatically command the probe to go down or wait for the manual command 5 11 4 SETTING OF This area has a selection of location categories that are used to set the functions Sample reagent Std Ctrl Dil Ise Disp Setting Procedure Choose the position category in the Setting of Area Click with the left side of the mouse on the Go area as soon as the area is clicked on it changes to End 300 Plus resets the arm and the values of the Offset column appear on the table Fig 7 Fig 7 LIASYS Diagnostic Arm Diluter Optic Plate Temperature Wash User Miscellaneous Global Setting Macro Setting Configuration Sample 1 734 1032 Down Arm Fusion Rar oreste ores P jue Sample 2 664 840 1 5 Prev The Keyboard Num Lock Manua Sample 3 612 680 2 B must be set to Sample 4 580 540 0 7 Sample 5 5b4 412 5 11 Sample 6 568 296 3 D Sample 7 600 196 1 B 1 Setting
15. MICS D 26 MICS D 10 VM EV1 O 2 D1 1 400 a 24V100 VM T 1 MP2 2 76384 302 vcc 76384 302 Qux 76384 304 VCC R21 LMC7101 VCC Qux R23 76384 304 MP3 EV3 24V100 2 3 76384 303 D3 1 400 2 EV4 24V100 VM J5 76384 302 VM EV5 VM EV6 2 2 D4 D5 1N400 1 400 EV5 MP3 1 1 24V100 24V100 VM 1N400 1 2 3 4 5 5 76384 305 8 76384 308 0 Emission Rev Description Checked Approved Approved Analyzer EP Medical Checked y Drawn R CORNACCHIA itle HYDRAULICS INTERF BOARD ize Document Number The present drawing is property of AMS A4 l any use without authorization will be MA 0041 9 00 prosecuted accordingly to the law Date Monday June 04 2001 Sheet 1 of 1 2 1 8 qns Br E aaux Emission Description Checked Approved The present drawing is property of AMS any use without Analyzer Via Forlanini s n c authorization will be prosecuted accordingly to the law Medical Tiburtina km 18 300 HYDRAULICS INTERFACE BOARD 1 1 1 of 1 R C 25 11 2001 Car Drawing Rev pproved Date MA 00419 00 23 11 2001 Chapter 05 DIAGNOSTIC PROGRAM CHAPTER 05 DIAGNOSTIC PROGRAM INDEX 5 DIAGNOSTIC PROGRAM 5 1 STATUS BAR 5 2 TEST FOLDER 5 3
16. March 2003 Rev 01 Page Service Manual ILab 300 Plus Chapter 2 GENERAL DESCRIPTION PROGRAMMABLE LOGIC It is made up of U10 PAL 16 8 and has the following functions ILab 300 Plus reset generation for the two Micros Each Micro is reset if RESA is present generated by U5 051233 10 when downloading begins RESB signal or for the entire length of program downloading of the other Micro BOOT and SELP signals the latter is provided by the first serial connector J2 The relative equations in PALASM format are RESP RESA RESB BOOT SELP RESR RESA RESB BOOT SELP Generation of X91 associated with one of two TX lines Micro P P91 and Micro R R91 to be directed toward the PC both in the operative phase and in the BOOT phase R91 is chosen if SELP is low downloading phase Micro or if R10 is low operative phase in which Micro R after ascertaining that the channel is free wants to transmit in all other cases X91 brings back P91 The corresponding equation in PALASM format is X9 SELP R91 SELP R91 R10 P91 R10 generation of the signals for programming the Micro R flash Activate PMD2E in the BOOT phase if SELP is high or in the operative phase if Micro P wants to write in flash low P66 Activate PVPPE in the BOOT phase if SELP is high Activate RMD2E in the BOOT phase if SELP is low or in the operative phase if Micro R wants to write in flash low R6
17. A G Rev 02 Reaction temperature Reaction Plate is out of range Either no sample or sample serum quantity below minimum or above maximum level for the declared container Either no reagent or reagent level below minimum or above maximum level for the declared container No Rack present during sampling Flags determined by test results out of range as setup in the Methods Flags determined by test results out of range as setup in the Methods Flags determined by test results out of range as setup in the Method Concentration calculation error due to foreseeable causes Asymptote January 2004 Page 4 Chapter 09 Error Signaling And Troubleshooting gt C Calibration Errors RBL missing No Reagent Blank Level Calibration missing No Standard or no Calibration curve STD Replicate insufficient Insufficient number of valid Standard Replicates STD Replicate outside CV Coefficient of Variation Percentage in the Standard Replicates over the set value Invalid Calibration Calibration curve not valid either because it is not monotonic or because the Fit is above the set value gt A Optic Density Errors Inversion I Reaction direction not in line with that set up End Point Limit P Values over the limits setup in the Methods Parameters Depletion Limit D Values over the limits setup in the Methods Parameters First Limit Values over the limits setup in the Methods Parameters
18. MA 00192 01 01 06 2001 Junction pins lt 1 01 SMBT3904 DT LMC7101B1M5 Sensor out 9SSE 30 0005 01 2 5SE 30 0005 07 Teflon Wire PVO shal Eliminata dicitura 12V nella conness tra il pin IN di U1 e il pin 2 di J2 vedi RMP 167 05 03 2003 Modificato valore C8 in 9 SE 30 0005 02 e C7 in 9 SE30 0005 01 07 07 2000 AN 07 07 2000 Emission 09 02 1999 A G 87 654321 Description Checked Date Approved Analyzer TO PRE HEATER INTERFACE BOARD The present drawing is property of AMS any use without Via Eorl bini amp me authorization will be prosecuted accordingly to the Medical Via Tiburtina km 18 300 System 00012 Guidonia Roma Drawn Description Scale Scale Sheet Checked SCHEMATIC LEVEL SENSOR BOARD 1 2 taw Jate L Massenzi 05 03 03 1 1 1 Drawing Rev Approved Date 9 SE 30 0005 XX A Gagliarducci 05 03 03 Modificato valore C7 07 07 2000 07 07 2000 Emission Description Description Analyzer m a ia Forlanini s n c Medical via Tiburtina km 18 300 System 00012 Guidonia Roma
19. SETTINGS AND ADJUSTMENTS 6 6 TEMPERATURE CHECK AND ADJUSTMENT 6 6 1 REACTION CUVETTE TEMPERATURE ADJUSTMENT AND CHECK 1 Turn on the ILab 300 Plus system and launch the Analyzer program Wait approximately one hour in order to allow the instrument to reach temperature balance at room temperature 20 The warm up time may vary from 30 minutes at about 21 C room temperature up to 100 minutes at about 18 C room temperature Launch the diagnostic program and select the Plate function Carry out the cuvette 16 in dispensation position Open the door and fill the cuvette 1 with 50 microliters of distilled water Select Configuration function Digit the password 1234 in the appropriate window and press 52 ee pel Insert the temperature probe Model type Chemitec S 501 with probe max 0 9 mm inside cuvette 1 from the door until it touches the bottom of the cuvette 8 Make sure the temperature read after 5 10 minutes is 37 0 C 0 2 0 3 If not move the cursor within the Plate window to select the desired temperature and then click on Save to memorize said temperature N B counts increase correspond to temperature decrease counts decrease correspond to temperature increase seven counts correspond to about one degree centigrade 9 Remove the temperature probe from the cuvette and empty it 10 Repeat the procedure from point 3 to 9 using in sequence c
20. tt tmd tbe 32 HYDRAULICS INTERFACE BOARD ede eec ee ae 33 Service Manual March 2003 Rev 01 Page 2 Chapter 2 GENERAL DESCRIPTION CHAPTER 2 GENERAL DESCRIPTION 2 GENERAL DESCRIPTION OF THE SYSTEM ILab 300 Plus is a random access counter top computer controlled clinical analysis instrument The system can perform 200 tests per hour and has a machine cycle of 18 sec Its execution time ranges from a minimum of 48 sec to a maximum of 756 sec depending on the analysis method chosen The first time the system is used for normal laboratory analyses the operator must configure the system based on the specific needs of that laboratory ie the chemical parameters the reagents racks and the normal calibrated and control values must all be defined The daily routine analyses will be carried out according to patient sample arrival in a sequential and continuous non stop manner The work list is organized using a loading rack holding 16 patient samples plus a STAT rack for 14 patient samples Rack loading is non stop The racks can accommodate both test tubes and micro caps The bar code for primary tubes is optional When the system is first turned on the analytical unit the computer and the color meter lamp are supplied with low voltage power 1 2 volts The sampling arm pre heater is turned off while the reaction plate heater the reagents refrigerating unit and the e
21. 5 using the Peristaltic Pump Setting Gage as illustrated in figure N B If power loss is experienced in the filling or emptying of liquid after a period of instrument activity perform the following operations before substituting or servicing any part s e Disconnect the liquid input tube from the malfunctioning pump e Insert a small amount of liquid using a syringe from the disconnected ends in order to wet the membranes Fig 4 Remove the syringe and reconnect the tube s perform functioning check as described in Section 6 3 2 1 Fig 4 6 3 4 MECHANICAL ADJUSTMENT OF THE PERISTALTIC PUMP gt N B Make sure the instrument ILab 300 Plus is turned off before performing this procedure The peristaltic pump tubes must be substituted every three to six months depending on instrument use ILab 300 Plus Service Manual Rev 04 January 2004 Page 42 Chapter 06 SETTINGS AND ADJUSTMENTS 6 3 4 1 How to substitute peristaltic pump tubes 1 Unscrew the two knobs on the cover located on the instrument headboard behind the washing station in order to arrive at the pumps assembly Fig 1 2 Unhook the hinged guide by lowering and rotating the guide s blocking bracket to the left thereby freeing the tubes Fig 3 3 Pull the tubes off their relative nipples and substitute with new ones 4 Remount repeating the above steps 2 through 1 in reverse order e Always use original replacement parts
22. AS 3 FROM POWER SUPPLY H TO SAMPLE RACK 00371 00 41 E a3 qi FILTER WHEEL MOT HOR MOT EXT ARM WASH STAT HOR MOT INT ARM REACTION PLATE MOT VERTICAL MOT ARM PERISTALTIC PUMP DILUTER MOTOR CONNECTION to P N wire 0 Emission Come da richiesta di modifica N 95 J18 A2 50 00551 00 Rev Material Drawn Date Analyzer coins one A Nicoletti 12 12 2001 J8 A2 50 00565 00 Medical Via Tiburtina km 18 300 System 00012 Guidonia R Checked Date A C 12 12 2001 J A2 90 00552 00 Treatment The present drawing is property of AMS any use without Approved Date authorization will be prosecuted accordingly to the law A G 12 12 2001 J17 A2 50 00550 00 Description Scale Sheet ELECTRONIC CONTROLLER ASSY Finish Car Drawin Rev es Description Checked Date Approved Date m H 2 P Ref A WASTE FRONT VIEW 50 0011 01 r1 ELECTRONIC CONTROLLER ASSY 0 Emission Description Checked Date Approved Date Rev Material Drawn Date Analyzer 17 03 2003 Medical Via Tiburtina km 18 300 Shocked De 00012 Guidonia Roma n
23. FIT F Values over the limits setup in the Methods Parameters RBL out of range Reagent Blank Levels outside the range Setup Sample outside Standard Sample absorbance outside the calibration curve ILab 300 Plus Service Manual Rev 02 January 2004 Page 5 Chapter 09 Error Signaling And Troubleshooting gt Results Edited Manually Results Edited E This symbol automatically appears whenever the operator has manually modified the obtained results This operation annuls all the symbols indicating errors which in this case will not be viewed gt I ISE Module Errors Air in the ISE Module Air present in the ISE Module hydraulic circuit Calibrate A drift Calibrate A drift in the ISE Module Noise in the ISE Module Background noise present values not reliable Out of Range in ISE Module Linearity values out of range Programming Errors All those software errors which are deemed unforeseeable are indicated using this symbol gt Result Asterisks In the event that the following situations and or error conditions occur the system will notify the user via a visualization of two asterisks in the Results field PHYSICAL ERRORS 1 very little or no sample 2 very little or no reagent 3 no rack ILab 300 Plus Service Manual Rev 02 January 2004 Page 6 Chapter 09 Error Signaling And Troubleshooting CONCENTRATION ERRORS 4 calculation error PROGRAMMING ERROR 5 all cases
24. HOME SENSOR INT ARM DILUTER HOME SENSOR Emission pPUMP DILUTER Y LINE HEN 1E The present drawing is property of AMS any use without authorization will be prosecuted accordingly to the law Analyzer Via Forlanini s n c Medical Va 18200 Drawn Date Descripti Scal Sheet Checked Dat P COMPLETE ARM ASSY uz iori 72052002 Sin Approved Date 9 15 0021 02 A Gagliarducci 22 05 2002 DILUTER ASSY NOTA Montare i raccordi pos 5 e 10 con nastro di teflon Riesame e approvazione MD14 01 del 06 09 2000 D S 06 09 2000 A G 06 09 2000 Modificato Rif 1 e 5 6 18 02 2000 S DeSantis 18 02 2000 Modificato Rif 4 ed inseriti Rif 9 15 16 6 16 02 99 S DeSantis 16 02 99 Modificato Rif 3 e 4 modificato Rif 10 era 9 01 0043 00 pos 28 10 98 S DeSantis 28 10 98 Emission Rev Description Checked Date Approved Date Drawn Date Analyzer Via Forlanini s n c Carboni 1 2 05 98 Medical Via Tiburtina km 18 300 System 00012 Guidonia Roma Checked Date S D S 2 05 98 Treatment The present drawing is property of AMS any use without Approved Date Ac 1205498 Description Scale Sheet ASSIEME DILUITORE 1 1 1 of 1 Finish Drawing Rev DILUTER ASSY 9 15 0007 00 Material
25. If this yellow triangle does light up the operator need simply click on it to access the relative visual text warning message indicating the cause of the signaled anomaly said window will open in that area dedicated to viewing data Following is a list of possible visual text Warning messages Liquid Alarm I Rinse Solution e Liquid Alarm II Distilled Water Liquid Alarm III Cleaning Solution e Temperature Out of Range e Host Serial Port cannot be opened Fatal Error an located in the upper right hand portion of the System Monitor mask It lights up red when activated If this red X lights up the operator need simply click on it to access the relative visual text message explaining the cause of the Fatal Error said window will open in that area of the mask dedicated to viewing data Following is a list of possible Fatal Error visual text messages e Programming Error e Internal Arm Error e External Arm Error ILab 300 Plus Service Manual Rev 02 January 2004 Page 2 Chapter 09 Error Signaling And Troubleshooting Filter Error 7 Axis Error Cuvette Block Error Wash System Error Diluter Error Block due to Instrument Lid being open ed during functioning Macro Error Maximum Time Error Instrument either not connected or turned off Decode Unit cannot be launched Host Link Module cannot be launched Host Link Module launching Error Work Executor cannot be launched
26. M1B M2C R22 10K R23 10K M2B M1C VCC BECA 1 Rev Description Checked Approved om Checked Drawn R CORNACCHIA itle STEPPER MOTORS DRIVER BOARD The present drawing is property of AMS Document Number Size MA 00188 01 Date Tuesday January 09 2001 any use without authorization will be prosecuted accordingly to the law Sheet 1 of 1 AMS P N 30 00188 01 NOTA Montare i Rif 2 dopo aver steso sui componenti da dissipare la giusta quantit di thermocompound Rif 6 Serrare i Rif 5 4 e 5 con una coppia pari a 15Nmm Come da richiesta di modifica N 152 aggiunte basette dissipatrici Emission Come da richiesta di modifica N 95 A N 06 08 2001 06 08 2001 Description Checked Date Approved Date The present drawing is property of AMS any use without Analyzer Via Forlanini s n c authorization will be prosecuted accordingly to the law Medical Tiburtina km 18 300 System 00012 Guidonia Roma Drawn Date G Pucci 04 09 2002 Description Scale Sheet Checked Date Drawing Rev Approved Date HOME SENSOR SLI 6 LEAKS L8 y 10 _OFFPR 76384 302 12 VM 44 PDL O 18 P71 18 R13 76384 304 EXT ARM 76384 304 INT ARM 76384 304 DILUTER 76384 304 22 o 125V 50K 24 26 o 12 5V NTC MICS D 26 12 5V R19 2 4K R20
27. R91 TX2 transmission toward Micro R s PC 5 TX transmission toward either Micro P s or Micro R s PC and the four RS232 TTL conversions P92IN P92 reception from the auxiliary device for Micro P R92IN R92 reception from the auxiliary device for Micro R RX2 R93 reception from the PC for Micro RX P93 R93 reception from the PC for Micros P and R are carried out through the U25 and U26 MAX202 devices ILab 300 Plus Service Manual March 2003 Rev 01 Page 16 Chapter 2 GENERAL DESCRIPTION CLOCK The system clock is supplied by quartz at 16MHz X1 connected to the Micro internal oscillator pins EXTAL and XTAL output TTL of this oscillator U1 67 is brought back on input XTAL of the Micro R oscillator LED There are two LEDs LD1 green LED for VM presence LD2 green LED for 12 5 presence BUZZER The acoustic signals are channeled to the LS1 buzzer and can be activated via the PDAR2 and or RDAR2 signals of the two Micros ILab 300 Plus Service Manual March 2003 Rev 01 Page 17 Chapter 2 GENERAL DESCRIPTION 2 5 2 STEPPER MOTORS DRIVER BOARD INTRODUCTION The STEPPER MOTORS DRIVER BOARD is the interface between the control board and the stepper motors GENERAL CHARACTERISTICS This board has been designed to be used in various systems or sub groups which require mechanical movement It can manage up to four stepper motors and has an open collector Darl
28. Result Abnormal A 2 This field indicates the normal status of Flags the result The following codes are valid values L Below Low normal H Above High normal LL Below Panic normal HH Above Panic normal Below absolute low under linearity gt Above absolute high over linearity IN Normal A Abnormal E Edited Nature of N Abnormality Testing Result Status 1 Imm System currently implements only two valid values F final results ILab 300 Plus Service Manual Rev 03 January 2004 Page 11 Chapter 08 Host Communication V operator verified approved result 10 Date of Change in N Instrument Normative Values or Units 11 Operator ID 12 Date Time Test Started 13 Date Time Test A 14 Date and Time of test completion Completed formatted as YYYYMMDDHHMMSS 14 Instrument ID N Legend R Required D Down Load O Optional U Up Load I Ignored N Never A Always S Sometimes Example Result Record Layouts R Upload Analyzer System RIII GLUI 70 97 UL 70 105 N IIF 1111 20020923114302 8 7 MESSAGE TERMINATOR RECORD L Field Field Title ae Up Load Mox Description and Valid Values oad Len 1 Record Type ID R A 1 This is a required field that contains an L identifying it as an Message Terminator Record 2 Sequence R A 1 For a message terminator this message Number should always be 1 3 Termin
29. Settings Control Panel Network At the Primary Network Logon function select Windows Logon 5 Select Start Settings Control Panel International Settings and select English United States Click on Time and select HH mm ss Click on Date and select dd MMM yy Reboot the computer 6 When required confirm the path to install the driver of the monitor 7 Set the Display Resolution at 800 x 600 Pixels 8 Disable all the options in the Power Management properties Select Standby Never Turn off the Monitor gt Never Turn Off Hard Disks gt Never In Power Schemes select Home Office Desk 9 Disable the Screensaver by selecting None 10 Disable the Background by selecting None 11 In the BIOS select APM and disable Power Management Suggested 12 In the BIOS select Peripheral and disable both the Sound and the LAN Suggested 13 Set the maximum number of colors at 65 536 16 bit To change the settings select Display Properties gt Settings gt Colors gt High Colors 14 Select Start Settings Control Panel Device Manager Ports Select Communication Port COMI Properties Port Setting Advanced Adjust both the buffers at the minimun level 15 Install the printer s driver Epson LX 300 the CD is in the packaging of the printer Select Settings Printer With the right button of the mouse click on the printer s icon Select Pro
30. from the Sampling Interface assy Fig 3 Remove the diluter and substitute it with the new one 5 remount repeat the above steps in reverse order from 4 to 1 6 After mounting the new module carry out the check procedure for mechanical functioning as described in Section 6 1 6 4 6 1 6 2 Substitution of the diluter micro pump N B Make sure the instrument ILab 300 Plus is turned off before performing this procedure 1 Remove the samples and reagents protective covers Fig 1 2 Remove the samples rack and reagents rack 3 Remove the teflon tube on the diluter head by unscrewing the fastening washer Fig 2 paying particular attention to leakage of liquid 4 Unscrew the four anchored screws indicated in Fig 2 unplug the J6 J8 and J13 connectors from the Sampling Interface assy Fig 3 5 Remove the diluter module from the instrument 6 Unscrew two fastening screws on the micro pump take out the pump and substitute it with the new one Fig 2 7 remount repeat the above steps in reverse order from to 1 8 After mounting the new micro pump carry out the check procedure for mechanical functioning as described in Section 6 1 6 4 ILab 300 Plus Service Manual Rev 04 January 2004 Page 27 Chapter 06 SETTINGS AND ADJUSTMENTS 6 1 6 3 Substitution of the diluter Electro valve N B Make sure the instrument ILab 300 Plus is turned off before performing this procedure 1 R
31. however it does loosen the OS4 optic sensor fastening screws Fig 3 and move it either up or down in order to correctly position the washing station Upon completion of this procedure tighten the optic sensor fastening screws and exit the diagnostic program by clicking on Diagnostic Carry out the functional check of the washing station as described in section 6 5 4 3 6 5 4 3 WASHING STATION FUNCTIONAL CHECK Turn on the ILab 300 Plus system first the instrument and then the computer Launch the ILab 300 Plus program and under System Monitor carry out a wash cycle and reading cycle of the cuvettes using water WBL Check system efficiency by comparing the obtained WBL values against the range of acceptance of WBL Make sure there is no leakage of liquid inside the analyzer ILab 300 Plus Service Manual Rev 04 January 2004 Page 54 Chapter 06 SETTINGS AND ADJUSTMENTS 6 5 5 WASHING STATION CUVETTE HOLDER ASSEMBLY 6 5 5 1 SUBSTITUTION OF THE CUVETTE HOLDER ASSEMBLY MAGNET N B Make sure the instrument ILab 300 Plus is turned off before performing this substitution procedure Remove the reaction plate cover Fig 1 Unscrew the four cross bas fastening screws and remove the cross bar Fig 1 Unscrew the four anchored screws of the reaction plate module Fig 2 Place the reaction plate vertically inside the instrument Remove the magnet s two fastening screws Fig 7 Remove connecto
32. in reverse order ILab 300 Plus Service Manual Rev 04 January 2004 Page 39 Chapter 06 SETTINGS AND ADJUSTMENTS Hydraulic interface board P Assembly Rear sid PN 23300041900 umps Assembly Rear side Micro Pump uP3 Assy Micro Pump uP2 Assy Peristaltic Pump Assy PN 23050044700 PN 23050040400 PN 23100028601 6 3 5 SUBSTITUTION OF THE PERISTALTIC PUMP MOTOR gt N B Make sure the instrument ILab 300 Plus is turned off before performing this substitution procedure 1 Unscrew the two knobs to remove the door located on the front elevation of the instrument Fig 1 and the two noticeable screws located on the rear panel Fig 2 to access the washing pump assembly 2 Unlock the hinged tube guide by lowering and rotating the guide lock to the left in order to free the tubes Fig 3 3 Disconnect the connector J6 from the Hydraulics Interface Board Rear side Fig 2 4 Unscrew the two motor fastening screws and remove the peristaltic pump assembly from its site Front side Fig 3 5 Unscrew the four screws which hold the motor and loosen the two grains which hold the peristaltic wheel 6 Remove the motor and substitute it with the new one 7 Remount repeating the above steps 6 through 1 in reverse order ILab 300 Plus Service Manual Rev 04 January 2004 Page 40 Chapter 06 SETTINGS AND ADJUSTMENTS Motor fastening screws Hinged guide tube Peristaltic Pump Rotor PN 23990090200 Hinged
33. of the sample rack and reagent rack doors the buttons indicators placed on the front panel of the instrument and the acoustic alarm buzzer The St by and Ready buttons are only lit indicators The STAT button instead actually turns off the acoustic alarms Signals regarding the presence of the five sample racks pass through this board ILab 300 Plus Service Manual March 2003 Rev 01 Page 32 Chapter 2 GENERAL DESCRIPTION 2 5 11 HYDRAULICS INTERFACE BOARD This board is used to distribute the following DARLINGTON commands EV3 EVA EV5 EV6 MP2 MP3 MP4 INTERLOOK or INTERLOCK In addition this board is used to distribute the peristaltic pump s motor signals U2 generates 5 V Ul is the operator that keeps the leak D9 on leak alarm control The parts connected to J9 and are designed to monitor the fluctuating liquids of peristaltic pump s two canals The microswitch signal transits to J8 which identifies if the cover is open IL 1 or closed IL 0 ILab 300 Plus Service Manual March 2003 Rev 01 Page 33 3 300 Plus Chapter 3 INSTALLATION CHAPTER 3 INSTALLATION INDEX NSA A TION wee ii tees eet Eten eee eee tt ite oett obe ve b redes 2 3T WNPACKING inen o e ete iet eet vielen be tiep ted 4 INSTALLATION 3 2 1 Installation site characteristics ccccsseecccccescececcescececcececccseseccecsesceceasenecees 4 3 3 ELECTRICAL POWER SUPPLY
34. samples If there is only one anomalous result that compromises the CV rerun it and if the result is acceptable no further operations are required Volume precision check Sampling line BIC Prepare two series of 32 samples each by using K2Cr207 4 gr l Use the same solution for both samples and reagent Program a new method with the following parameters Method name BIC Type End Point Sample volume K2Cr207 4 gr l 3uL Reagent volume RINSE SOLUTION 300 uL Filter 340 nm Incubation time 116 sec Calculation factor 1000 BIC Procedure 1 Program the BIC method using the above parameters and configure a reagent rack 2 Enter in the calibration screen and select RBL for BIC method 3 Put RINSE SOLUTION as reagent and sample fourteenth position and Start the Calibration 4 Program 64 BIC fill 32 conical samples cup with K2Cr207 4 gr l 5 Load the racks on sample positions 1 and 2 of the Analyzer 6 Start the Analyzer At the end of the last sampling move the sample racks into positions 3 and 4 The mean value for each of the 32 sample series must be between 350 450 The coefficient of variation percentage CV 96 must be lower than 1 6 96 for each series of 32 samples If there is only one anomalous result that compromises the CV rerun it and if the result is acceptable no further operations are required ILab 300 Plus Service Manual Rev 02 January 2004 Page 35 Chapter 05 DIAGNOSTIC PROGRAM Backlash Dil Due to the mecha
35. 1 2 REACTION PLATE CYCLE After reagents and samples have been placed in cuvette 1 the reaction plate will rotate counter clockwise to position 31 so as to bring the first cuvette to be analyzed in front of the color meter for reading with one or two wavelengths as required The plate will then moving counter clockwise carry out all the readings of any other prepared cuvettes After having effected all the readings the plate will move clockwise to its initial position minus one cuvette ready for a new dispensing Therefore the reaction cuvettes will move clockwise 1 2 3 4 for their dispensation and washing and counter clockwise 4 3 2 1 for their reading ILab 300 Plus Service Manual March 2003 Rev 01 Page 4 Chapter 2 GENERAL DESCRIPTION 2 2 SAMPLING ARM OPERATIONAL SEQUENCE 1 The sampling arm lifts up from the washing well and carries out a washing cycle 2 The arm moves toward the specific reagent container while the diluter aspirates an air bubble to separate the rinse column from the reagent 3 The arm descends into the reagent to the level indicated by the sensor and aspirates the required volume of reagent If the method requires a line prime volume an extra amount of reagent not used in the analysis will be aspirated before the quantity of reagent necessary for the analysis along with a smaller air bubble for separation 4 While the diluter aspirates a second air bubble the arm rises and t
36. 10K PRE HEATER 5 76384 308 N R21 2 4K R22 10K ALFD3 D8 4 7V R23 220 R24 240 OS7 R25 2 4K R26 10K ALFD1 R27 330 R28 240 51 R29 2 4K R30 10K 76384 302 D6 R18 2K2 R15 10K R32 750 U4 LM7805 TO220 D10 4 7V 12v 1K R12 2602 24V 2K2 D3 1N5819 R11 10K V1 INT ARM J4 76384 308 CON6MX R51 220R J16 76384 305 G20UT 74LS00 U5B 74LS00 74LS00 EXT ARM J5 MICS D 12 76384 308 VERT ARM J3 DILUTER 16 MICS D 10 76384 308 76384 308 LS1 RES1 44 amp 4 14 R60 3 Q6 1 2N2907 5V BIP 8A E R58 2R2 0 Riferimento RMP 60 Rev Description Checked Approved Approved Analyzer id Medical Checked System The present drawing is property of AMS any use without authorization will be prosecuted accordingly to the law Wendnesday January 10 2001 oom fall AMS P N 38 00192 Emission Description Checked Approved The present drawing is property of AMS any use without Analyzer Via Forlanini s n c authorization will be prosecuted accordingly to the law Medical Tiburtina km 18 300 uidonia Roma Drawn Date System 227 tute ono ee A Nicoletti 01 06 2001 SAMPLING INTERFACE ASSY Hori R C 01 06 2001 Car Drawing Rev Approved Date
37. 11 12 13 14 substitution procedure Remove the cover panel of the reaction plate Fig 1 Unscrew the four cross bar fastening screws and remove the cross bar Fig 1 Unscrew the 4 fastening screws on the reaction plate assembly Fig 2 Remove the J1 connector and the ground wire from the Reaction Chamber Motor Interface board Fig 2 Remove the J1 J14 connectors and the ground wire from the Reaction Plate Interface board Fig 2 Open the peristaltic pump assembly panel cover Unscrew the two fastening screws to make free the support that join the six tubes coming from the washing station probes Disconnect the seven tubes coming from the washing station probes and the air tube inserted on the micro pump P4 coming from the porous pad on fifth probe of the washing station Remove the reaction plate from the instrument Remove the lamp s power supply wires connected to the Lamp Regulator board by loosening the two screws on the M1 connector Fig 4 Unscrew the lamp s fastening screws and remove it from its housing Unscrew the four fastening screws on the motor support in order to access the filter wheel Unscrew the fastening screw that holds the elastic band that holds the filters Remove the filter from its housing and substitute it with the new one Remount the assembly repeating the above steps 11 through 1 in reverse order After remounting reseat the lamp and carry out the electronic adjustment procedures as des
38. 2004 Page 3 Chapter 01 INTRODUCTION REACTION VOLUME Minimum 300 ul Maximum 670 ul SAMPLING ARM A single mechanical arm provides all sampling operations with e Capacitive liquid level sensing e Reagent pre warming at 37 C e Automatic probe washing DILUTER Integrated module without syringe with the following specifications e Sample volume 3 0 ul 99 ul 1 pl incr e Reagent 1 volume 3 0 ul 500 ul 1 ul incr e Reagent 2 volume 3 0 ul 330 ul 1 ul incr e Reagent 3 volume 3 0 ul 330 ul 1 ul incr PRECISION CV lt 1 at 3ul READING SYSTEM Direct Photometry OPTIC SYSTEM Photometer interferential double channel filter wheel Wavelength 8 narrow band interferential filters from 340 nm to 620 nm Light source halogen lamp 6V 10 W Linear range 0 001 2 500 Abs Resolution 0 0001 Abs OPTICAL PATH 10 mm WASHING STATION 9 9 9 Composed of five probes that empty wash and dry the reaction cuvettes REACTION PLATE 60 semi disposable cuvettes Cuvettes Q C continuously computer controlled Incubation temperature 37 1 4 1 Computer amp Software feature TYPE CPU MEMORY ILab 300 Plus Service Manual IBM Compatible Pentium III 500 MHz 512 Kb Cache or plus RAM 128 Mb or plus Hard Disk 10 Gb or plus Rev 02 January 2004 Page 4 Chapter 01 INTRODUCTION Flop
39. 5 New photometer assy 2 Channel PN 23100010800 Pre Amplifier ADC Read Channel PN 23300010700 Motor support Opto coupler assy PN 23910002300 Gain Reference Channel Stepper Motor assembly PN 23910001901 Pre Amplifier ADC Ref Channel PN 23300010703 ILab 300 Plus Service Manual Rev 04 January 2004 Page 35 Chapter 06 SETTINGS AND ADJUSTMENTS 6 2 4 SUBSTITUTION OF THE OPTO SENSOR gt N B Make sure the instrument ILab 300 Plus is turned off before performing this peta dh EY 10 11 12 13 14 15 substitution procedure Remove the cover panel of the reaction plate Fig 1 Unscrew the four cross bar fastening screws and remove the cross bar Fig 1 Unscrew the 4 fastening screws on the reaction plate assembly Fig 2 Remove the J1 J2 connectors and the ground wire from the Reaction Chamber Motor Interface board Fig 2 Remove the J1 J2 J14 connectors and the ground wire from the Reaction Plate Interface board Fig 2 Open the peristaltic pump assembly panel cover Unscrew the two fastening screws to make free the support that join the six tubes coming from the washing station probes Disconnect the seven tubes coming from the washing station probes and the air tube inserted on the micro pump P4 coming from the porous pad on fifth probe of the washing station Remove the reaction plate from the instrument Remove the lamp s power sup
40. CYCLE The washing station carries out its operation by alternating upward and downward movement In its downward movement phase the probes are suitably guided to carry out the following operations e The first probe using its central cannula removes the read sample while the external cannula dispenses shower fashion the wash solution this operation is repeated twice e The second probe operates exactly like the first but uses distilled water to wash and repeats the operation three times e The third probe dispenses distilled water into the cuvette so that an optics check can be performed if the results are negative the cuvette is discarded e The fourth probe aspirates and removes the previously dispensed distilled water e The fifth probe is a drying pad which removes any residual moisture from the sides of the cuvette All these operations are part of the routine operation of the instrument Every reaction cuvette is washed at the end of each round of analysis The reusability of each reaction cuvette is always tested before the next round of analysis ILab 300 Plus Service Manual March 2003 Rev 01 Page 7 Chapter 2 GENERAL DESCRIPTION 2 5 ELECTRICAL SCHEMES DESCRIPTION 2 5 1 ANALYTICAL CONTROL BOARD CPU INTRODUCTION The ANALYTICAL CONTROL BOARD C P U integrated in the ILab 300 Plus system is the heart of the low level real time processing management GENERAL CHARACTERISTICS The board has b
41. EAEE RRE RER 555 5 CIGIS NINNIN e e j U2 9 10 ILab 300 Plus Service Manual March 2003 Rev 01 Page 10 Chapter 2 GENERAL DESCRIPTION P70 P71 I U23A 19 25 PFOTO PFOTO2 PFOTO3 23 23 CIS ies P73 P74 P75 P76 P77 P80 P81 P82 P83 P84 9 3 9 7 9 9 9 5 Oo 92 gt S nN ON lt lt PFOTOd PINP9 PINPIO PINPII alae QW PINPI2 PINPI3 POOOUT 23 RDY2 RDYI OSRI NINININ AJA Quy ny By amp lt O O m i lt 00 lt 95 _ HD A 00 O OO l N i d 95 N I asi iaci kar RIBIS POSR3 PCLKB POSRA PPWM PDAR PCLKD PLEAK PCLKC PADCI PSLI PADC2 14 J17 14 PINP14 Liquid 2 alarm _ Go 5 U sO Di ny amp Nile nN m nN 7 9 24 9 9 00 2 NIA CO CO ON ON ES Ce 2 nN UII 85 S18 d ILab 300 Plus Service
42. In the following situations and or error conditions the results field will contain a 07 if the result is less than zero 2 if the result is equal to zero OPTIC DENSITY ERRORS 3 Flag signaling depletion limit 4 Flag signaling inversion ILab 300 Plus Service Manual Rev 02 January 2004 Page 7 Chapter 09 Error Signaling And Troubleshooting 9 2 TROUBLESHOOTING GUIDE PROBLEM POSSIBLE CAUSE SOLUTION Repeatability of results insufficient Sample Probe dirty 2 Clean the Sample Probe as described in Chapter 07 Maintenance Hydraulic leak and or air bubble in the hydraulic circuit sampling Check Sample Probe fit Check the fit of the hydraulic tubes and their connection if necessary substitute the tubes and or adjust their connections fittings Wash solution is contaminated If the wash solution contains contaminating particles e g mold dust lint these micro particles can cause errors during the WBL running lt Change the wash solution Clean the Wash Solution Bottle s and carry out the Hydraulic Circuit wash procedure as described in Chapter 07 Maintenance Deterioration of the Reagent s 2 Substitute the bad reagent s Reaction cuvettes not dried correctly after being washed Check the Tip used to dry the cuvettes after washing to make sure it is in good working condition If necessary clean the Tip or change it following the
43. LEVEL SENSOR BOARD Checked The present drawing is property of AMS an authorization will be prosecuted accordin Drawn Approved y use without ly to the law 09 02 99 Dat Scale Sheet Checked Date at Drawing Rev Approved 9 MA 50 0005 01 ES A G D 09 02 99 Modificato valore C8 07 07 2000 07 07 2000 Emission Description Checked The present drawing is property of AMS an Analyzer Via Forlanini s n c authorization will be prosecuted accordin Approved y use without ly to the law 09 02 99 Medical va Tiburtina km 18 300 wem neum Description Scale Sheet Checked D LEVEL SENSOR BOARD 09 02 99 G Drawing Rev Approved Da at at t 09 02 99 SCLK J1 23 10 DRDY1 J1 15 U4 TC7660 ADC1 ADC1 J1 24 2 ADC2 G2 J1 5 LV VOUT LEAKP L6 EA CAP DRDY2 2 10 OFFPL CAR L12 gt VM OSC 14 BCU 16 __ 20 SCLK J1 23 10 22 12 5 ADC2 ADC2 J1 2 24__ 1 26 ot 12 5V V GND U LM7805 TO MICS D 26 MICS D 10 V BCU J1 14 D6 R20 2K2 CUVETTE o HOLDER SOLENOYD LED YELLOW VM CON4MX R10 2K2 D4 R11 10K REACTION LED YELLOW R27 2 4K R28 10K TRAY TEMP P72 J1 25 SENS PWRES J10 1 FILTERS HOME SENSOR LO HI I IS
44. Manual March 2003 Rev 01 Page 11 Chapter 2 GENERAL DESCRIPTION TAB 2 Micro R Signals Micro I O Buffer Conn Signal R10 Signal Function Connector P14 Synchronization micro P Synchronization 2 micro P RI2 R14 RIS R RI6 icro 20 21 22 23 24 25 26 27 R30 R31 Synchronization 3 micro P Power led opto 3 Synchronization micro Synchronization 2 micro N N OO 59 AU o ZIDA v Synchronization 3 micro c P 2 Diluter pump SS 2 8 23 RINP2 805 RINP3 8 1 RINP4 8 8 87 RINP7 Notued 89 RINPS 8 RENA Motor A enable 9 8 INP Leak 0 0000000 GG mle w t RINPS Notued RINP Notued AL O 0 S cic Qo 09 RENB RENC END GG _ 92 95 lt lt 90 90 90 EN UTIO SCLK ADCI ADC 2 serial Clock Lamp of HN ny BY Go me Go Go Go 05 95195 60 06 o o6 9 aassssssosos AA z oo GIG pe pnh 1 oo m E GC NI lt lt 95 c 5 RE NIN wW
45. P81 12 PINP10 P23 12 PINP4 P77 8 4 R23 PANT pez 591774 1 4 PINP11 P24 9 bs 2 PINP5 PB3 R24 PINP13 83 7 PINPI2 202 Sao PINP6 P95 13 RRDY1 R25 PINP10 PINP14 P84 5 PINP13 P26 202 2A PINP7 PB5 15 RADC2 R26 PINP11 PINP12 PB7 PINP14 P27 PINP8 P94 RRDY2 R27 ve E BED ve A AVCC C25 0 1u C35 1uF D4 R39 6K8 RTS 1N4148 R40 3K3 413__ 10 BOOT RR6 10K8 C RR7 10K8 C C37 1uF U25 MAX202 921 92 C17 0 1u C18 BUZZER C38 1uF 1 VCC 10 100 65 CX2 13 1Q0KR65 0 1u CON26A PG1 PFOTO1 PG2 PFOTO2 PFOTO3 PINP Ro VMgapyi R93 4 R900UT ALFD1 TX2 PPWM PSCLK PADC2 RG1 MICRO R VCC VCC A L VCC CX1 0 1u P33 D11 1A2 1A3 1A4 2A1 2A2 2A3 2A4 C39 1uF 010 CON26A P34 D12 7 8 AVCC 12 5V Q1 Q PNP RMD2 O92 2 1 P66 LWR P65 HWR P64 RD P63 AS VCC XTAL EXTAL GND NMI RES STBY E P62 BACK P61 BREQ P60 WAIT GND P53 A19 P52 A18 P51 A17 P50 A16 P27 A15 P26 A14 PA7 TIOCB2 PA6 CS4 TIOCA2 PA5 CS5 TIOCB1 PA4 CS6 TIOCA1 PA3 TIOCBO TCKD PA2 TIOCAO TCKC PA1 TEND1 TCKB PAO TENDO TCKA MICRO R BRACCIO ADRMICRO 0 P35 D13 P36 D14 P37 D15 vec 10 11 1 12 2 P25 A
46. a power potential greater than 0 5 KW currently available on the market can be used NO BREAK MODULE UPS Uninterrupted Power Supply This module provides two important functions stabilises the main line power supplies current to the instrument in case of a main line power failure 3 2 3 CONNECTION OF THE ACCESSORIES 3 2 3 1 POWER SUPPLY Fig 1 Plug use the feeder cable supplied with the instrument The sticker indicates the power supply voltage and the values of the fuses 3 2 3 2 COMPUTER INSTRUMENT CONNECTION The instrument and the Personal Computer are connected by one serial RS232 standard cable P N 23935005501 which provides the hardware support for the communication ILab 300 Plus Service Manual Rev 02 January 2004 Page 5 Chapter 03 INSTALLATION 3 2 4 ATTENTION The following label is found at the rear of the instrument CAUTION EQUIPMENT UNDER VOLTAGE EVEN WHEN THE TOP COVER IS OPEN NOTE THE REAR PANELS OF THE INSTRUMENT MUST NEVER BE OPENED WITHOUT HAVING FIRST SWITCHED THE INSTRUMENT OFF AND DISCONNECTED THE ELECTRICITY CABLE THE MAINTENANCE AND CLEANING PROCEDURES FOUND IN CHAPTER 07 OF THIS MANUAL MUST BE RESPECTED AT ALL TIMES REMEMBER TO FOLLOW THE DECONTAMINATION PROCEDURE IN CASE OF INSTRUMENT REMOVAL SEE CHAPTER 07 32 5 SYMBOLS m ATTENTION READ THE INSTRUCTIONS IN THE USER MANUAL TERMINAL OF TOTAL MASS PROTECTION CONDUCTOR 32 6 REGULATORY COMPL
47. cover panel of the washing station and mechanically align the pad better Fig 5 5 Upon completion of this procedure tighten the fastening screws on the bottom cover of the washing station and exit the diagnostic program by clicking on Diagnostic 6 Carry out the functional check of the washing station as described in section 6 5 4 3 Fig 5 Fig 6 Down Cover Top cover fastening screw Horizontal mechanical adjustment screws ILab 300 Plus Service Manual Rev 04 January 2004 Page 53 Chapter 06 SETTINGS AND ADJUSTMENTS 6 5 4 2 WASHING STATION VERTICAL ALIGNMENT 1 2 3 Turn on the ILab 300 Plus system first the instrument and then the computer Launch the diagnostic program and select the Plate function Reset by clicking on the appropriate key Make sure the Home Sensor Reaction Plate window lights up green Select the Wash function Reset by clicking on the appropriate key Make sure the Home Sensor Washing Station window shows a green light Select several times Home and Down by clicking on the appropriate keys Make sure the washing station probes enter the reaction cuvettes freely and totally unhindered Pay particular attention to the drying pad placed on probe number five The upper limit must be reached before the mechanical end of run The lower limit must allow the drying pad to touch the bottom of the cuvette The washing station does not normally need vertical mechanical adjustment If
48. drawing is property of AMS any use without Analyzer Via Forlanini s n c authorization will be prosecuted accordingly to the law Medical Tiburtina m 18 300 m T 00012 Guidonia Roma m Description Scale Checked Date LAMP PWS BOARD 1 R 3 Cornacchia 04 05 99 Drawing 19 Roa Date 9 50 0004 0 30 0004 090 0 04 03 99 WLSTt_ WLST3 WLST5 VM 24V J1 1 2 3 WLST2 5 6 8 19 10 11 12 r7 13 44 WLST4 15 16 MICS D 16 R6 R1 U1 10K 330R WLST1 848 U2 OPB848 R10 R12 05 10K 330R WLST5 OPA848 OPA848 0 Emission Rev Description Checked Approved Approved Analyzer EP 5 Medical Checked System R CORNACCHIA itle SAMPLE RACKS IDENTIF BOARD ize Document Number The present drawing is property of AMS A4 any use without authorization will be MA 00446 00 prosecuted accordingly to the law Date Saturday January 12 2002 Sheet 1 of 1 2 1 B 72 00 0 N d SAV Emission The present drawing is property of AMS any use without Analyzer Va Forlanini snc authorization will be prosecuted accordingly to the law Medical Tiburtina km 18 300 mm E SAMPLE RACKS 1 of 1 R Cornacchia 11 01 2002 Car Drawing Rev Approved Date IDENTIFICATION BOARD o 0046 00 AGaaliardueci 11 01 2002 24V 01 LM7 VIN
49. field Configuration Folder in the Diagnostic Program by taking into account that 7 COUNTS CORRESPOND TO ABOUT 1 C 16 After any modification in the Parameter values repeat the steps from 7 through 14 17 At the end of the adjustment procedure get out from the Diagnostic Program and from the Instrument software execute a WASH cycle then followed by the WBL ILab 300 Plus Service Manual Rev 04 January 2004 Page 65 Chapter 06 SETTINGS AND ADJUSTMENTS ILab 300 Plus Service Manual Rev 04 January 2004 Page 66 Chapter 06 SETTINGS AND ADJUSTMENTS ILab 300 Plus Service Manual Rev 04 January 2004 Page 67 Chapter 06 SETTINGS AND ADJUSTMENTS 6 6 3 REFRIGERATION ASSEMBLY TEMPERATURE CHECK Warning Keep the cooling fan protection grid placed at the bottom of the refrigerated rack unencumbered and free of dust 1 Place a reagent container containing distilled water in a position of the refrigerated reagents rack 2 Turn on the 300 Plus system instrument and computer Wait approximately one hour in order to allow the instrument to reach temperature balance at room temperature 20 3 Place the temperature probe in the reagent container and check that the temperature is approximately 10 C lower than room temperature If not substitute the reagents racks holder Fig 1 4 Remove the reagent container containing distilled water and exit from the analyzer progra
50. modification in the Parameter values repeat the steps from step 1 through 7 Close the main cover and after having checked the correct setting of the reaction plate temperature select Temp Test Run in the Temperature Folder inside the Diagnostic program Verify that the temperature probe or others tools are correctly positioned so to avoid their interference with the moving parts of the instrument During this procedure step in fact the Sampling arm the washing Station and the Reaction Plate will become active By pressing START the system will sample seven reaction cuvettes in sequence At the end of the sampling cycles the main cover will be unlocked Open the small door for cuvettes replacement Measure and take note of the cuvettes temperature starting from the seventh up to the first cuvette by dipping and gently shaking the temperature probe into the liquid At the end of measurements press WASH The system is ready for a new cycle ILab 300 Plus Service Manual Rev 04 January 2004 Page 64 Chapter 06 SETTINGS AND ADJUSTMENTS Note 3 The measure obtained from the seventh cuvette is the best indication of the pre heater temperature The measure obtained on the first cuvette is the nearest to the reaction plate temperature previously adjusted to 37 0 37 2 C The objective is to obtain the same temperatures into all the seven cuvettes 37 37 29 15 If necessary modify the value in the ARM parameter
51. never lubricate the peristaltic pump roller bearings e After prolonged instrument inactivity verify the efficiency of the peristaltic pump tubes Please note if the instrument is not able to completely empty the washing well check the condition of the tube and make sure that the space between the hinged guide and the rotor is approximately 1 5 mm Any necessary adjustments in order to optimize pump aspiration in relation to the newly substituted tube can be made by turning the relative screw Fig 5 using the Peristaltic Pump Setting Gage as illustrated in figure 6 See Service News 9 dated 21 05 2003 Screw for regulating peristaltic pump aspiration Fig 5 ILab 300 Plus Service Manual Rev 04 January 2004 Page 43 Chapter 06 SETTINGS AND ADJUSTMENTS Peristaltic Pump Setting Gage PN 23010120100 6 4 REACTION PLATE 6 4 1 REACTION PLATE MECHANICAL ADJUSTMENT 1 Turn on the ILab 300 Plus system and launch the Analyzer program Remove the reaction plate cover Fig 1 2 Launch the diagnostic program select the Optic function and turn on the light by clicking on the designated key 3 Reset the filter wheel by clicking on the appropriate key 4 Select key Spare to bring filter position 9 to the reading position 5 Select the Plate function Reset by clicking on the appropriate key Make sure that the Home Sensor Reaction Plate window lights up green 6 Make sure that the light
52. of the channel of the Probe3 is disabled Cycle lasts 3790mS used 400ul 50ul of Dist Water LLLLLLDLLELPELPLLLELELPLELPLLPLDLPLPELRPLLLELPELDELRPLELELPELRPPLLLPLPLPLLPELLLPLIPLDLLPLILPILPILILDILI Before the Probe 4 the cuvette is moved in front of the photometer to be verified Probe 4 ON EVI empitying of the channel of the Probel is enabled uP4 ON uPump Probe5 0 ON Pump peristaltic remains ON until the end of the cycle Washing Station goes down 570115 ON empitying of the channel of the Probe4 is enabled Wait 600mS Washing Station goes up 570mS OFF EVI empitying of the channel of the Probel is disabled uP4 ON uPump Probe5 0 OFF Pump peristaltic EV3 empitying of the channel of the Probe4 is disabled Cycle lasts 3790mS LLLLLLLLLLLDLDLLDLLLLLLDLLLLDLDLDLLLLLLLLLLLLDLLLLDLLLLLLDLLLDLDLLDLLLLLLLDLLLDLDLDLDLLLLLLLLLLLDLDL KK KK 5 ON EVI empitying of the channel of the Probel is enabled uP4 ON uPump Probe5 0 ON Pump peristaltic remains ON until the end of the cycle Washing Station goes down 570115 Wait 2100mS Washing Station goes 570mS OFF EVI empitying of the channel of the Probel is disabled uP4 ON uPump Probe5 0 ON Pump peristaltic Cycle lasts 3790mS LLLLLLLLLLLDLLLDLLLLLL
53. procedure described in Chapter 07 Maintenance Light bulb not stable 2 Light bulb nearing the end of its 2000 hour life cycle duration or premature deterioration In both cases change the light bulb following the substitution procedure described in Chapter 07 Maintenance Insufficient volume quantity of the various Rinse Cleaning and Distilled Water solutions This type of problem can present itself either when the instrument is first turned on due to a lack of liquid in one or more bottles or during test running whenever the involved liquid has been finished Refill the required bottle If the instrument is running tests it will automatically Pause Wait until sampling is suspended then refill the involved bottle with the required liquid Rinse Cleaning Distilled Water Press Start to continue running the rest of the programmed tests This operation will not adversely affect the already run tests ILab 300 Plus Service Manual Rev 02 January 2004 Page 8 Chapter 12 Ise Module CHAPTER 12 MODULE INDEX 12 1 ELECTROLYTE MEASUREMENT SYSTEM jsscstscetss scotia sadenadas prot Itin 2 12 1 1 PRODUCT DESCRIPTION apiid Mende un 2 12 2 ELECTROLYTE MEASUREMENT SYSTEM FEATURES AND BENEFITS 3 12 3 TECHNICAL SPECIFICATION 2 etre teh etr re ter eda cec peo oed I 4 12 4 SYSTEM OPERATION ISB THEOR
54. red when open The fields Chassis Leak Alarm Instrument Leaking Wash Station Leak Alarm Wash Station Leaking Plate Leak Alarm Reaction Plate Leaking turn green when there is no leaking and red when there is The following two fields signal the alarms for the bottles containing the liquid waste material Liquid Wastel Alarm Liquid Waste2 Alarm turning green when the liquid level is not excessive and red when the waste bottle indicated by the alarm is almost full Fig 4 Rack Door s Optical Switch Arm Leak Alarm Vertical Arm s Optical Switch Rinse Level Alarm Distilled Water Level Alarm Internal Arm s Optical Switch ST BY Indicator Mome Sensor Door aig panel button STAT Door s Optical Switch Diluter s Ready Indicator Optical Switch Sample3 Door s Optical Switch 5 External Arm s Sample3 Door s Optical Switch Indicator Optical Switch Cleaning Level Alarm Sample2 Door s Optical Switch Samplel Door s Optical Switch ILab 300 Plus Service Manual Rev 02 January 2004 Page 5 Chapter 05 DIAGNOSTIC PROGRAM The fields in the figure can be two different colors either green or red for the indicators in Home Sensor Leak Liquid Alarm and front panel button and either green or dark gray for the indicators in Rack Door except for the field Rgt Smp Door that can be either green or red The fields Vertical Arm
55. specially formulated to be sensitive to sodium ions The potassium and chloride electrodes employ similar designs with appropriate selective membrane materials The potential of each electrode is measured relative to a fixed stable voltage established by the double junction silver silver chloride reference electrode An ion selective electrode develops a voltage that varies with the concentration of the ion to which it responds The relationship between the voltage developed and the concentration of the sensed ion is logarithmic as expressed by the Nerst equation E E RT log e C nF Where E The potential of the electrode in sample solution E The potential developed under standard conditions RT nF A temperature dependent constant termed the slope s Log Base ten logarithm function e Activity coefficient of the measured ion in the solution C Concentration of the measured ion in the solution A comparative method of measurement is utilized First the ISE module measures the potential developed when the sample is positioned in the electrodes Next Calibrant A is positioned in the electrodes The difference in the two potentials is related logarithmically to the concentration of the measured ions in the sample divided by their respective concentrations in the Calibrant solution Since the difference in potentials and the concentration of the sodium potassium or the other ions in the Calibrant solution are known the compute
56. that particular laboratory However the manufacturer recommends thorough washing at least once every two weeks It is extremely important that the user not underestimate the risks associated with mold and dust particles They are to be regarded as a serious hazard as they can be the cause of instrument malfunction The wash solution bottles are located on the right side of the analyzer 7 5 1 WASHING SOLUTION BOTTLES CLEANING PROCEDURE 1 Turn off the Analyzer Pull the level sensor connectors out from the bottle caps 2 Take the caps off the bottles and empty them 3 Fill each bottle with a 5 sodium hypochlorite solution 4 Clean the inside of each bottle using a bottlebrush in order to remove all traces of mold and or residue 5 Leave the sodium hypochlorite solution stand in the bottles for at least ten minutes 6 Empty the bottles rinse them repeatedly and well with tap water and then twice more using distilled water 7 Dry the bottles 8 Fill the bottles with their proper solutions 9 Replace the bottles in their respective housings 10 Close the bottles and reconnect the level sensors 11 Carry out two Wash Cuvettes cycles and two WBL cycles Check system efficiency by comparing the WBL values and the test results obtained against the laboratory s quality control values ILab 300 Plus Service Manual Rev 03 January 2004 Page 6 Chapter 07 Mantenance 7 6 POROUS PAD WASHING The T
57. the Instrument software execute a WASH cycle then followed by the WBL Further information The reaction plate has been studied in order to maintain the dispensed liquids at the set temperature and not to heat them up Consequently it is really important to adjust the pre heater temperature as much as possible near to the reaction plate temperature value 37 0 37 2 C If a thermostatic bath should be not available then apply the following CHECK WHETHER THE INTEGRATED CHIP 71 IS INSTALLED ON THE CONTROL PANEL BD POS U2 see fig 1 AND REPLACE IT WITH THE INTEGRATED CHIP LMC 7101 A or or TLV 2461 BEFORE APPLYING THE FOLLOWING PROCEDURE e Turn on the system and wait in order to allow the instrument working temperature settlement The warm up may vary from 30 minutes at about 21 C room temperature up to 100 minutes at about 18 C room temperature e During warm up time remove the protection cover of the Control Panel Board Front Side Light Indicators See fig 1 e During warm up time launch the diagnostic program and select the Temperatures Folder in the Diagnostic Program e During warm up time select Calibration Sensor and carry out the three steps by following the indications showed on the screen Replace the calibrator resistor with the temperature probe Note 1 Now the temperature probe and the service probe function can be used as a thermometer Route th
58. the existing files Choose the language 3 necessary run again the installation program Select Service Install the new program TEST ILAB 4 Enter the ILab 300 Plus software Check the Parameters Option Password SH Important The file Analyzer mdb for software version 1 0 8 is NOT COMPATIBLE with the software version 1 0 7 and previous ILab 300 Plus Service Manual Rev 02 January 2004 Page 10 Chapter 03 INSTALLATION NOTE when the setting is completed save the new Analyzer MDB file 3 5 FIRMWARE UPGRADING A SOFTWARE FIRMWARE UPGRADING PROCEDURE Firmware upgrading procedure To verify the revision of the firmware point out the mouse on the figure of the chip at the bottom of the screen in the ILab 300 Plus program The version of the firmware will apeare Open the black rear cover and remove the plastic protection to have access at the Analytical Control Board 1 Copy the file ALYSSWXX A20 in the TestILab folder The file ALYSSWXX A20 is the firmware 2 3 4 Start the Test program by double clicking Test exe With the selection on Plate Micro 1 click on the Read Down Load key A window named Write Log with When the downloading is completed press Write Confirm key will appears Click OK 5 It will appears the window HFD Hitachi Flash Download Click on File key and select a20 on the list files of typ
59. the hydraulic circuit must be washed depends operating conditions environment of the single instrument and the quality of the distilled water used in that particular laboratory The manufacturer recommends thorough washing at least once a month It is extremely important that the user not underestimate the risks associated with mold and dust particles They are to be regarded as a serious hazard as they can be the cause of instrument malfunction The hydraulic circuit input cannulas are located inside the bottles on the right side of the Analyzer 7 7 1 HYDRAULIC CIRCUIT CLEANING PROCEDURE 1 Turn on the Analyzer 2 Prepare a bottle containing 500 ml of a 5 sodium hypochlorite solution 3 Insert the three aspiration cannulas located inside the liquids bottles into the bottle containing the sodium hypochlorite solution 4 Carry out a Wash cuvettes cycle and then a cycle cycle 5 Wait for fifteen minutes Clean and dry the three cannulas and then insert them into a bottle containing distilled water 6 Carry out a Wash cuvettes cycle and then a WBL cycle Repeat 7 Insert the three aspiration cannulas back into their respective bottles Said bottles should have in the meantime been cleaned and filled with a fresh supply of the required solution 8 Carry out two Wash cuvettes cycle and then a cycle Check system efficiency by comparing the WBL values and the test results obtain
60. the instrument In this mode all temperature regulation of reagents and reaction disk are ON SWITCHING OFF From the standby mode turn the instrument off by pressing the main switch located on the left side of the instrument Remove the reagents and place them in the refrigerator SHUTDOWN PROCEDURE This procedure must be carried out whenever the 300 Plus is to be switched off for several days e Take out the tubing from the deionized water bottles rinse and clean the tubes and insert them in a bottle filled with deionized water e Click the Start Button Select Wash all cuvettes Water Blank Level and then Repeat this procedure three times Take the tubing from the bottles and leave them in air Click the Start Button and select Wash all cuvettes Water Blank Level and Turn the instrument off Remove the sensor caps and empty the three bottles Rinse them with deionized water To restart the system place the three tubes in their respective bottles Click the Start Button Select Wash all cuvettes Water Blank Level then Repeat this procedure twice For ILab 300 Plus with the ISE module Move down the Ise door Disengage the Ise module to have access at the upper inlet port of the assembly Dispense 500 uL of Calibrator A into the upper port e Seal the inlet port with Parafilm Empty the Calibrator A bottle Rinse the bottle
61. 115 and J17 connectors from the Sampling Interface assy unplug the ground wire remove the sampling arm Loosen the fastening screw and lift the sampling arm s protective cover Fig 4 in order to arrive at the M7 motor Remove the M7 motor fastening screws Fig 5 Loosen the motor pulley screws Fig 6 Take out the M7 motor and substitute it with the new one Fig 7 Lift the pulley to approximately 0 5mm from its upper limit and tighten its screws Fig 8 Push the M7 motor outward as shown in Fig 9 and holding it in this position so as to maintain the belt in tension tighten the motor fastening screws To remount repeat the above steps in inverse order from 8 to 1 Warning Do not tighten the protective cover s set screw as this could result in mechanical malfunction of the sampling arm s vertical movement Fig 2 ILab 300 Plus Service Manual Rev 04 January 2004 Page 13 Chapter 06 SETTINGS AND ADJUSTMENTS Warning After having substituted the motor it is necessary to mechanically align the probe with respect to the wash well and center all the other positions by following the procedures rovided in Section 6 1 1 Alignment and Adjustments Pre heater guide support Protective cover Fig 1 Anchored screws Fig 3 Arm assembly without base and Sampling Interface Board PN 23915002000 ILab 300 Plus Service Manual Rev 04 January 2004 Page 14 Chapter 06 SE
62. 13 CON26A RINP1 RINP2 6 RINP3 8 RINP4 RINP5 13 RINP6 15 _RINP7 17 RINP8 1 RINP7 RINP8 C40 1uF C41 1uF C42 1uF RR4 10K8 C 0 Riferimento RMP 60 b Rev Description RR5 10K8 C GMS prawn RCORNACCHIA itle ANALYTICAL CONTROL BOARD Size Document Number The present drawing is property of AMS MA 00195 01 Date Monday January 08 2001 any use without authorization will be prosecuted accordingly to the law Sheet 1 27 28 2 CX3I Cx1 0 1u 0 1u 0 1u 0 1u 0 1u 5 7 8 Si 24 zixa 61x3 d d EIX3 gol Ls guu D ur uH 56 100106 N d Sny x 213 Emission Come da richiesta di modifica N 60 Description Checked Approved The present drawing is property of AMS any use without Analyzer Via Forlanini s n c authorization will be prosecuted accordingly to the law Medical Tiburtina km 18 300 uidonia Roma Drawn 4 Date System 707 Come A Nicoletti 12 12 2000 ANALYTICAL CONTROL BOARD 1 of 1 R C 12 12 2000 Car Drawing Rev Approved Date MA 00195 01 12 12 2000 R10 750R C3 0 1u D17 LED YELLOW RES 2 Res CLKA T 2 DRA 5 PDA 10 pe D18 LED YELLOW UT1 UT2 UT3 UT4 UTS UT6 UT7 UT8 UT9 UT10 WLST1 LK WLST2 IL WLST3 NC KLRD
63. 2 21 20 19 18 16 15 12 Lu 10 9 8 7 L5 5 4 2 EE Not included in the tubes kit 0 The present drawing is property of AMS any use without authorization will be prosecuted accordingly to the law Forlanini s n c Via Tiburtina km 18 300 System 00012 Guidonia Roma Description HYDRAULIC DIAGRAM LIASYS NEW Scale 1 1 5 Drawn Date Date Sheet Checked 7 _ Drawing si 00457 00 A Gagliarducci 12 03 2002 PERISTALTIC PUMP WASHING STATION MANIFOLD rey ee in m zi ju VS SEE usur s See PEA 51 E TO EV2 amp EV3 VERTICAL HOME SENSOR HOR HOME SENSOR EXTERNAL ARM HOR HOME SENSOR INTERNAL ARM DILUTER HOME SENSOR amp DILUTER EXTERNAL ARM INTERNAL ARM VC VHC eR DILUTER MOTOR VERTICAL ARM MOTOR HORIZ MOTOR EXT ARM HORIZ MOTOR INT ARM Ni p Es oy n i QUT EH FROM POWER SUPPLY FROM 1 00188 01 1 PRE HEATER CONNECTION FROM 00195 01 J10 LLL ALL LNL LOL EI AMI MS D IA PASS SS ESR SSNS SE SSS SSS SSS SSS ESS SES SSS SI 222 DEL DEPP DDL DDL PPL DEL DD DDL DDL DRL DL DDL LADLE DDL DDE PPL DDL DELS zz FROM 1 00188 01 8 HOR HOME SENSOR EXT ARM HOR
64. 2 SAMPLING ARM OPERATIONAL 5 2222 5 2 3 SAMPLING SYSTEM sra outer teet so eae e ratae Nu edo den epe 6 WASHING SEAT LOIN ate cato Cerise odes teen cede up eed 7 ZI WASTING STATION CN CLE ura E 7 WASHING STATION CYCLE 2 3 BLECTRICAL SCHEMES DESCRIPTION amp 2 5 1 ANALYTICAL CONTROL BOARD CPU 2 2 0 qe 8 2 5 2 STEPPER MOTORS DRIVER BOARD qas 18 FAX ego C 21 25 0 SAMPLING INTERFACE ASSY 255 dette tette bd esee ette qud tav 23 23 3 SAMPLING INTERFACE ASSY 24 2 34 LEVELSENSORBOARD S IS 2 25 2 35 95 REACTION TRA Y INTBERBAGQE itii mentita ee boo 26 2 533 REACTION TRAY INTERFACE uec ore ake 24 ILab 300 Plus Service Manual March 2003 Rev 01 Page 1 2 5 6 2 5 7 2 5 8 2 5 9 2 5 10 2 5 11 ILab 300 Plus Chapter 2 GENERAL DESCRIPTION REACTION CHAMBER MOTOR INTERFACE eere 28 PRE AMPL ADC tau Uds at ad sea NOM ni us Fev MEE 29 PHOTOMETER EAMP PWS ad oa pee utei dae 30 SAMPLE RACKS IDENTIFICATION BOARD ree 3l CON TROP AINE
65. 23350081600 23350081700 23350081800 23350081900 23350082700 23350082000 23350082800 23350082900 23350083000 23350083100 23350083200 23350083300 23350083400 23350083500 23350083600 23350083700 23350083800 23350083900 Service Manual Service Parts sorted by IL Part Number Description Gauge Peristaltic Pump Joint Bottles Rinse Water Cleaning Micro Pump 4 Micro Pump 2 Connection Joint Assembly Interlock Assy Micro Pump 3 Stat Sample Rack Reagent Panel Sample Panel Assy Photometer Electronic Controller Assy Peristaltic Pump Assembly Motors Assy for S Arm P Pump Belt arm horizzontal Pre Ampl ADC Board Main Channel Pre Ampl ADC Board from S N 0205011 Ref Channel Pre Ampl ADC Board up to S N 0205010 Ref Channel Stepper Motor Drivers Bd Sampling Bd Reaction Tray Interface Bd Analytical Control Bd Motor Plate Interface Bd Control Panel Hydraulic Interface Bd Racks Identification Bd Interlock Switch Extractor for connectors Lumberg Sodium Electrode Potassium Electrode Chloride Electrode Reference Electrode Ise Control Board Bubble Detector Peristaltic Pump Waste Assy Peristaltic Pump Cal A Assy Pump Motor Cal A Pump Motor Waste Head Tube Perilstatic Pump Ise Connection Tube 6mt O Ring 4 Pcs Motor Cable Electrode Compression Plate Alignment Electrode Tool Inlet Sample Pot Assy Output Connector Assy Lower Kit Gasket Gasket compression January 2004 Rev 02 2 IL
66. 3 Chapter 05 DIAGNOSTIC PROGRAM The three areas enable the operator to verify multiple functions as specified below Test Folders checks the functionality of the ILab 300 Plus various sub systems The individual functions are illustrated later on Optical Switch Sensor Status O S S S visualizes the sensor status pertaining to micro 1 that controls the reaction plate and the cuvette wash station Fig 3 as well as to micro 2 that manages the arm and the dilutor Fig 4 Fig 3 Wash Station Optical Switch Cover Lock Switch Plate Leak Alarm Filter Wheel s Optical Switch Chassis Leak Alarm Micro 1 Reaction Wash Station Leak Liquid Alarm Cuvette Holder s Optical Switch Wash Station s Leak Alarm Liquid Wastel s Alarm Reaction s Plate s Optical Switch Liquid Waste2 s Alarm Furthermore there are three types of unused fields empty inactive or those reserved for future use While the program is running the fields given in the figure can be either of two distinct colors red or green The fields e Wash Station s Optical Switch O S Filter Wheel s O S Reaction Plate s O S Cuvette Holder s O S turn green when the specific device is in the home position and turn red when not in the home position ILab 300 Plus Service Manual Rev 02 January 2004 Page 4 Chapter 05 DIAGNOSTIC PROGRAM The field Cover Lock turns green when the cover is closed and turns
67. 3 Hematology 1111111111 Analyzer PIIIBIOSKIII MW5910 Smith 11 19861002 M Park Avenue New System York NY 10002 1111111111111 20020923 11 Hematology 111111111 8 5 TEST ORDER RECORD O Field Field Title Down Up Max Description and Valid Values Load Load Length Record Type ID R A 1 This is required field that contains an identifying it as an order 2 Sequence Number R A 3 This field starts with 1 for the first Test Order Record and is incremented by 1 for each additional Test Order Record within the record This will be reset to I whenever another patient record ILab 300 Plus Service Manual Rev 03 January 2004 Page 7 Chapter 08 Host Communication is transmitted 3 Specimen ID R A 15 Although the operator manually edit this field at any time the value of this field is usually assigned by the laboratory computer before down loading The Analyzer uses and reports its results based on the assigned specimen ID 4 Instrument Specimen I N ID 5 Universal Test ID I N 9 This is a four component field e Universal Test ID Code I N not used e Universal Test ID Name I N not used R A e Universal Test ID Type not used e Manufacturer s or local code 6 characters This is the code defined in the Analyzer 6 Priority I N 7 Request Ordered I N Date Time 8 Specimen Collected
68. 3910001700 Fig 3 Washing Station probes assembly PN 23910000600 ILab 300 Plus Service Manual Rev 04 January 2004 Page 51 Chapter 06 SETTINGS AND ADJUSTMENTS 6 5 2 SUBSTITUTION OF THE WASHING STATION OPTIC SENSOR gt N B Make sure the instrument ILab 300 Plus is turned off before performing this substitution procedure Remove the reaction plate cover Fig 1 Unscrew the four cross bas fastening screws and remove the cross bar Fig 1 Unscrew the four anchored screws of the reaction plate module Fig 2 Place the reaction plate vertically inside the instrument Remove the J3 connector from the Reaction Plate Interface Fig 2 fv b cam obs Dus EE Unscrew the two fastening screws on the optic sensor and substitute it with the new one Fig 3 7 Remount repeating the above steps 6 through 1 in reverse order 8 After substituting and remounting carry out the mechanical adjustment and functional check procedures as described in section 6 5 4 6 5 3 SUBSTITUTION OF THE WASHING STATION MOTOR N B Make sure the instrument ILab 300 Plus is turned off before performing this substitution procedure Remove the reaction plate cover Fig 1 Unscrew the four cross bas fastening screws and remove the cross bar Fig 1 Unscrew the four anchored screws of the reaction plate module Fig 2 Place the reaction plate vertically inside the instrument Remove the J3 connector from the Reaction Plate Int
69. 3965003100 23935002201 23300019301 23050051900 23910006101 23905007400 23905007500 23905007200 23905007300 23350081700 23915002400 23050052000 23300019201 23905006401 23350081400 23F 35001900 23901055800 23050045901 23910001700 23910001601 23910001901 23300018801 23910002200 23900125300 23C10048300 23965002701 23910000600 23905006300 Service Manual Service Parts sorted by Description Description Output Connector Assy PC Boards Service kit ILab 300 Peristaltic Pump Assembly Peristaltic Pump Cal A Assy Peristaltic Pump Waste Assy Potassium Electrode Power Cord Power Supply Pre Ampl ADC Board Main Channel Pre Ampl ADC Board from S N 0205011 Ref Channel Pre Ampl ADC Board up to S N 0205010 Ref Channel Pump Motor Cal A Pump Motor Waste Racks Identification Bd Reaction Cuvette 60 pieces Reaction Plate Heather Reaction Tray Interface Bd Reagent Panel Reaction Plate Assy Reagent Rack 1 from 1 4 std ctrl Reagent Rack 2 from 5 13 Reagent Rack 3 from 14 23 Reagent Rack 4 from 24 33 Reference Electrode Refrigerated Reagent Rack assembly Sample Panel Sampling Bd Sampling Probe Sodium Electrode Solenoid Valve 2 way Special Key Stat Sample Rack Stepper Motor washing probes Stepper Motor Assembly motor with pulley Stepper Motor Assembly Photometer Stepper Motor Drivers Bd Temperature Sensor Tygon Tube 1 m Tubes Adapter 20 pcs Tubes Kit Washing Station Probe Ass
70. 4 DIGITAL CONVERSION AREA 2 commands START STOP Sample Channel Conversion Performs analogical digital conversion of the principal channel START STOP Reference Channel Conversion Performs an analogical digital conversion of the reference channel 5 5 5 STATUS COMMAND AREA Send Visualizes the commands sent by the program to the instrument hardware Receive Visualizes the instrument hardware s response to the commands sent by the program ILab 300 Plus Service Manual Rev 02 January 2004 Page 16 Chapter 05 DIAGNOSTIC PROGRAM 5 6 PLATE FOLDER DIAGNOSTIC Rinse The Plate Folder is subdivided into six areas OPERATIONS SENSOR STATUS USER MOTOR ON OFF REACTION PLATE STATUS COMMAND 9 9 9 9 o ILab 300 Plus Service Manual Rev 02 January 2004 Ready Page 17 Chapter 05 DIAGNOSTIC PROGRAM 5 6 1 OPERATIONS AREA 3 commands Home Back Performs the same movement made previously but in the opposite direction To Disp Brings the cuvette indicated on the sheet menu below the dispense position To Optic Brings the cuvette indicated on the sheet menu to the colorimeter 5 6 SENSOR STATE AREA The status of the plate sensor is indicated in this area 5 6 3 USERAREA 1 command Cuvette Holder ON OFF Alternately turns ON and OFF the cuvette holder 5 64 MOTOR ON OFF AREA 1 command Motor ON OFF Engages Disengages the motors to allow a
71. 4 Page 18 Chapter 06 SETTINGS AND ADJUSTMENTS M6 Motor s belt PN 23935003100 M6 Motor fastening screws M6 Motor Assy PN 23100039900 6 1 4 3 Substitution of the M5 motor N B Make sure the instrument ILab 300 Plus is turned off before performing this procedure Important pay special attention to the Pre heater when removing or servicing the sampling arm 1 Remove the sampling probe 2 Remove the samples and reagents racks protective covers 3 Remove the samples rack and reagents rack 4 Unscrew the four cross bar fastening screws Remove the cross bar by slipping out the Pre heater guide support Fig 1 5 Remove the waste tube from the wash well 6 Remove the teflon tube on the diluter head by unscrewing the fastening washer Fig 2 paying special attention to leakage of liquid 7 Unscrew the four anchored screws indicated in Fig 3 unplug the J1 J2 J3 JIS and J17 connectors from the Sampling Interface assy unplug the ground wire remove the sampling arm 8 Take the Sampling Interface assy out by unplugging the connectors and unscrewing the fastening screws Fig 10 ILab 300 Plus Service Manual Rev 04 January 2004 Page 19 Chapter 06 SETTINGS AND ADJUSTMENTS N B In order to be able to remove the M5 motor from its support it is necessary to first partially disassemble the module as shown in Fig 12 9 Unscrew the three fastening screws Fig 11 an
72. 6 Activate RVPPE in the BOOT phase if SELP is low Service Manual March 2003 Rev 01 Page 14 Chapter 2 GENERAL DESCRIPTION The relative equations in PALASM format are PMD2E P66 BOOT SELP PVPPE BOOT SELP RMD2E R66 BOOT SELP RVPPE BOOT SELP FLASH PROGRAMMING VOLTAGE The PMD2E PVPPE RMD2E RVPPE signals pilot 4 017 Darlingtion sections whose outputs PEMD2 PEVPP REMD2 REVPP signals activate respectively the PNP Q2 Q3 1 and Q4 transistors which bring back the 12V respectively on pin MD2 and pin VPP of Micro and Micro R SERIAL INTERFACES The first serial of each Micro signals P90 and P92 for Micro R90 and R92 for Micro R is dedicated to communicating with its own auxiliary device respectively J1 and J3 For the reception channel of the second serial Micro is linked to serial 1 of the RX Micro R can be linked to serial 2 of the PC R93 RX2 coming from J5 shifting the tin soldered jumper from pins 2 3 of J12 to pins 2 1 linked in parallel with those of Micro P and therefore linked to series 1 of the PC R93 RX soldered jumper on pins 2 1 f J12 For the transmission channel of the second serial Micro R is linked to serial 2 of the PC R91 TX2 ILab 300 Plus Micro can be linked to serial 1 of the PC P91 TX shifting the tin soldered jumper from pins 2 3 of J11 to pins 2 1 share the transmission to the PC with the
73. 65 cm Length 100 cm WEIGHT 65 Kg OPERATING ENVIRONMENT Temperature 18 C 32 Relative humidity 20 85 ILab 300 Plus Service Manual Rev 02 January 2004 Page 5 Chapter 01 INTRODUCTION 1 4 4 Installation requirements POWER REQUIREMENTS Input Voltage 90 250 Vac Input Frequency 47 63 Hz Power consumption 300 W for the analytical unit 400 W for the work station SAFETY REGULATIONS EN 61010 1 1993 A2 1995 in compliance with the main European safety directives 73 23 CEE e 3 68 CEE ELECTROMAGNETIC EMC 89 336 CEE 92 31 CEE Directives COMPATIBILITY EN 55011 Class B Group 1 EN 50081 1 1992 EMC EN 55022 ENV 50140 ENV 50141 EN 60601 1 2 EN 61000 4 Warning A steady power supply 4 1096 must be provided for the instrument If it is not the manufacturer highly recommends the use of UPS Uninterruptible Power Supply No break module ELECTRONIC STABILISER ILab 300 Plus Service Manual Rev 02 January 2004 Page 6 Chapter 2 GENERAL DESCRIPTION CHAPTER 2 GENERAL DESCRIPTION INDEX 2 GENERAL DESCRIPTION OF THE SYSTEM dei ieget io erc ena 3 21 SANALY TIC AIC YCEB uias ERE NR prae tb oliin date be ud RR e i EP DEL 4 211 REACTHON PLA TE utet ROM editur e A miM dH 4 2 1 2 REACTION PEATE CYCLE ior Arat tis et d vata es 4 2
74. 901003800 Halogen Lamp 23935001600 Tubes Kit complete 23965002701 Tygon tubing mt 23900125300 Kit for E V Diluter connection 1 23990090600 Probe 23905006400 Probe new coating 23905006401 MicroPump Assembly 5 55 23910002801 Complete Probe Assembly 23910006200 Comp Probe Assembly New C D 23910006201 Diluter head Teflon Fitting 10 23C101004201 Diluter fitting 10 23C1010122200 E V Rinse fitting 10 23C1900125400 Solenoid Valve 1 P 23F35001900 MicroPump up4 Assy 1 23050040300 MicroPump up2 Assy 1 23050040400 MicroPump up3 Assy 1 4 23050044700 Manifold Assembly 1 i 23050040500 Inlet Outlet fitting for rinse 1 ii 23010122400 Lamps kit 9 08 23965003500 Na electrode 1 23350081400 K electrode 1 23350081500 Cl electrode 7 23350081600 Reference electrode 1 di 23350081700 Peristaltic Pump Tubing head 1 di 23350083000 ISE inlet tubing connection 6 mt 1 23350083100 ILab 300 Plus Service Manual Rev 03 January 2004 Page4 Chapter 07 Mantenance 7 3 SAMPLING PROBE CLEANING PROCEDURE 1 Turn off the Analyzer 2 Use only lint free paper toweling or gauze 3 Dampen the gauze or paper toweling with distilled water and clean the outside of the sampling probe Wipe the probe from the top downwards only This is to avoid that any bits of cloth paper or lint fibers accidentally enter the probe itself 4 The manufacturer suggests that once weekly the above des
75. A D conversion and RS 232C communications The microprocessors apply proprietary mathematical algorithms to electrolyte sensor output voltage converting them to clinical units of mmol L Sensor Inputs e Na Electrode e Reference Electrode K Electrode e Upper Bubble Detector Electrode Lower Bubble Detector 10 9 MAINTENANCE The Electrolyte Measurement System has been designed to require very little operator maintenance The only daily maintenance required is to run the Cleaning Solution after the last sample of the day REPLACEMENT PART 3 6 9 12 MO MO MO MO Pump Tube X Na Electrode X K Electrode X CI Electrode X Reference Electrode X Reagents Refill REAGENT as required by testing needs Recommended Maintenance Replacement Schedule more than 100 samples per day REPLACEMENT PART 3 6 9 12 MO MO MO MO Pump Tube X Na Electrode 10 000 samples K Electrode 10 000 samples Cl Electrode 10 000 samples Reference Electrode 10 000 samples Reagents Refill REAGENT as required by testing needs ILab 300 Plus Service Manual Rev 02 January 2004 Page 11 Chapter 12 Ise Module 12 10 TROUBLE SHOOTING GUIDE or damaged damaged 3 Component failure Replace board E a Low Slope Micali oument of sensors Remove and replace sensors to Na or K lt 45mV decade re seat 1 lt 35 mV decade or 2 Deterioration of calibrator Replace Cal B
76. BLY 55 SUBSTITUTION OF THE CUVETTE HOLDER ASSEMBLY MAQGNET 55 MAGNETIC TRIGGER tisse p Ru diu t Do Une de ME TRUE 56 TEMPERATURE CHECK AND ADJUSTMENT 58 REACTION CUVETTE TEMPERATURE ADJUSTMENT AND CHECK 58 TEMPERATURE CHECK AND ADJUSTMENT USING KIT P N 55 01204 00 39 REFRIGERATION ASSEMBLY TEMPERATURE CHECK 68 RACKS HOLDER ALIGNMENT ssis 69 MECHANICAL ALIGNMENT OF THE SAMPLES RACKS HOLDER 69 MECHANICAL ALIGNMENT OF THE REAGENTS RACKS HOLDER 70 ILab 300 Plus Service Manual Rev 04 January 2004 Page 3 Chapter 06 SETTINGS AND ADJUSTMENTS 6 SETTINGS AND ADJUSTMENTS 6 1 SAMPLING ARM 6 1 1 ALIGNMENT AND ADJUSTMENTS 1 Turn on the 300 Plus system instrument and computer 2 Launch the Diagnostic program select Global Setting Wait until the instrument has completed the reset procedure 3 Make sure that all the home sensors of the Sampling Arm Vert Int Arm and Ext Arm light up green 4 Make sure that the probe is centered with respect to the wash well If not loosen the fastening screws on the external arm and mechanically align the arm on the wash well paying attention to center the probe with respect to the wash well If absolutel
77. Error during execution of 1 command 9 1 2 RESULT FLAGS Result Flags are categorized under the following group headings Each group is identified by a symbol as listed here below X cu gt W p PHYSICAL ERRORS CONCENTRATION ERRORS CALIBRATION ERRORS OPTIC DENSITY ERRORS RESULTS EDITED MANUALLY ISE MODULE ERRORS PROGRAMMING ERRORS ILab 300 Plus Service Manual Rev 02 January 2004 Page 3 Chapter 09 Error Signaling And Troubleshooting Every Result Flag signaling an error is accompanied by a symbol representing the group it is part of The operator need only click on the small red square next to the Result Flag symbol to access the visual text message explaining the cause s of the signaled error In the central column of the following tables the user will find those symbols which signal the type of error encounter as used in the print out of the final report These symbols can be modified by the operator in the Parameters section under print options WARNING The use of the Error Symbols in the print out of the results inclusion and or exclusion IS UNDER THE DIRECT AND SOLE RESPONSIBILITY OF THE USER 9 1 3 DESCRIPTION OF RESULT FLAGS X Physical Errors Temperature Error No Sample No Reagent No Rack R Concentration Errors Very Low and Very High Low Alert and High Alert Low and High Linearity Limit Calculation Error ILab 300 Plus Service Manual L H
78. GENERAL DESCRIPTION J9 710 11 113 J7 Pin 5 J12 J2 Pin 14 J3 J4 15 16 18 77 72 01 Page 24 Chapter 2 GENERAL DESCRIPTION 2 5 4 LEVEL SENSOR BOARD 1 2 The integrated U4 circuit generates a trigger signal for U3 where the sampling probe is connected on Pin 6 via C2 The capacity variation produced by the contact between the sampling probe and a liquid determines a voltage variation on Pin 3 of U3 which ranges from a value close to zero to one which tends towards 5 V This signal is then further processed by U2 and QI and is placed in output from the board on J2 Pin 1 ILab 300 Plus Service Manual March 2003 Rev 01 Page 25 Chapter 2 GENERAL DESCRIPTION 2 5 5 REACTION TRAY INTERFACE This board controls various functions J2 J3 J4 and J5 are the input connectors for the opto sensors of the filters wheel of the washing station of the reaction plate and of the cuvette holders This information is transferred to the Analytical Control Board CPU using the OS2 OS3 OSA and OSB signals via The ALFDS signal controls power supply to the series of the three emitting diodes contained in the opto sensors connected to J2 J3 and 14 ALFDI functions in a like manner relative to the opto sensor connected to J5 Liquid leakage signal enters on J7 and is processed by whose output LEAKP returns via 11 on the CPU Plate temperature is detected by the N T C sensor co
79. HOOTING to be done OPTIONS to be done BAR CODE READER to be done ISE MODULE SPARE PARTS LIST March 2003 Rev 01 Chapter 01 INTRODUCTION CHAPTER 01 INTRODUCTION INDEX 1 INERODUCHON deka cea Rona rh Ud au Eu Ra ARES RAN 1 1 1 THE AIM OF THE TECHNICAL MANUAL 2 1 1 000 2 1 2 SYSTEM INTRODUCTION 3 D b idee bei ene bee dd 2 1 3 PRECAUTIONARY MEASURES 5 ppt aT etc te ne ien qe i 2 L S L CHBEMICALDL RIS 2 13322 ELECTRICAL RISKS 2 2 1 3 3 MECHANICAL RISKS reote 3 1 4 TECHNICAL OPERATING FEATURES iecit teoria rh died sse 3 1 5 1 COMPUTER amp SOFTWARE FEATURES ends nag HIS E PER 4 OR TION Sade SAGE ROG AAG LR BONA GAR O 5 1 5 3 DIMENSIOS WEIGHT amp ENVIRONMENT eene eene 5 1 5 4 INSTALLATION REQUIREMENTS iis iiid ec haere tente bee aida 6 ILab 300 Plus Service Manual Rev 02 January 2004 Page 1 Chapter 01 INTRODUCTION 1 INTRODUCTION 1 1 THE AIM OF THE TECHNICAL MANUAL This manual has been written in order to supply the technical staff the persons who are responsible for the maintenance and for resolving instrument failures a complete and detailed guide of the 300 Plus analyzer in accordanance w
80. I N Date Time 9 Collection End Time I N 10 Collection I N Volume Units 11 Collector ID I N 12 Action Code I N 13 Danger Code I N ILab 300 Plus Service Manual Rev 03 January 2004 Page 8 Chapter 08 Host Communication 14 Relevant Clinical I N Info 15 Date Time Specimen I N Received 16 Specimen Type R A 1 This is numeric field indicating the type of specimen The Imm System uses the following ASCII characters 0 Serum 1 2 Urine 17 Ordering Physician I N 18 Tel Number 19 User Field No 1 I N 20 User Field No 2 I N 21 Field No 1 I N 22 Field No 2 I N 23 Date Time Result I N Reported Last or Modified 24 Instrument Charge I N 25 Instrument Section I N ID 26 Record I A 1 The field indicates the direction of the transmission O Down Loading F Up Loading 27 JReserved Field I N 28 Location or Ward of I N Specimen Collection 29 Nosocomial I N Infection Flag 30 Specimen Service I N ILab 300 Plus Service Manual Rev 03 January 2004 Page 9 Chapter 08 Host Communication 31 Specimen Institution I N Legend R Required D Down Load O Optional U Up Load I Ignored N Never A Always Sometimes Example Test Order Record Layouts O Download Host OITIIARIO2II GLU lH LELLELEEEEO EEEEEE EE ELO EL T 1 1 A
81. IANCE The ILAB 300 PLUS instrument complies with Safety EN 61010 1 1993 2 1995 therefore meeting the essential requirements of L V D 73 23 EEC and 93 68 EEC EMC EN 61326 1 therefore meeting the essential requirements of Electromagnetic Compatibility Directive 89 336 EEC 92 31 ILab 300 Plus Service Manual Rev 02 January 2004 Page 6 Chapter 03 INSTALLATION 3 3 INSTALLATION ACTIVITY Customer Instrument S N Service Engineer Date During the preinstallation visit the laboratory area should be inspected in the light of the following requirement gt Temperature of the laboratory between 18 and 32 C Yes No gt Main Power supply between 90 e 250 Vac Yes No gt Is it necessary an electronic stabilizer Yes No gt Worktable Minimun size 110 x 70 cm plus PC and Printer Yes No Presence of vibration Yes No Q Presence of good ventilation minimun 10 cm Yes No No direct exposure to sunshine Yes No Installation Activity Unscrew the screws fixing the crate located in the lower sides Raise the wood crate and take out all the packaging material Check the integrity of all the parts Check the Packing List Place the instrument on the workbench and level it by adjusting the front feet Check the ground connections Raise manually t
82. ILab 300 Plus Service Manual ILab 300 Plus Service Manual P N Revision 02 January 2004 This publication and all materials including software concerning the products of ILab 300 Plus System are of proprietary nature and are communicated on a strictly confidential basis they may not be reproduced recorded stored in a retrieval system transmitted or disclosed in any way and by any means whatsoever whether electronic mechanical through photocopies or otherwise without IL s prior written consent Information contained herein is believed by IL to be accurate in any event no responsibility whether express or implied is assumed hereby by IL for or in connection with the use thereof or for infringement of any third party right which arise therefrom or from any representation or omission contained herein Information is subject to change and or updating without notice N Instrumentation Laboratory Instrumentation Laboratory S p A Viale Monza 338 20128 Milano GENERAL INDEX ILab 300 Plus SERVICE MANUAL CHAPTER 1 CHAPTER 2 CHAPTER 3 CHAPTER 4 CHAPTER 5 CHAPTER 6 CHAPTER 7 CHAPTER 8 CHAPTER 9 CHAPTER 10 CHAPTER 11 CHAPTER 12 CHAPTER 13 ILab 300 Plus Service Manual GENERAL INDEX INTRODUCTION SYSTEM DESCRIPTION INSTALLATION ELECTRICAL SCHEMES AND DRAWINGS DIAGNOSTIC PROGRAM SETTINGS AND ADJUSTMENTS MAINTENANCE HOST INTERFACING TROUBLES
83. ING ARM N B Make sure the instrument ILab 300 Plus is turned off before performing this substitution procedure Tu dm ubl e Remove the sampling probe from its housing Remove the samples and reagents racks protective covers Remove the samples rack and reagents rack Unscrew the four cross bar fastening screws Remove the cross bar by slipping out the Pre heater guide support Fig 1 Remove the waste tube from the wash well Remove the teflon tube from the diluter head by unscrewing the fastening washer paying special attention to leakage of liquid Unscrew the four anchored screws indicated in Fig 5 unplug the J1 J2 J6 J8 J13 J15 and J17 connectors from the Sampling Interface assy Disconnect the ground wire and following the procedure provided in section 6 1 5 1 remove the Level Sensor and Pre Heater assembly ILab 300 Plus Service Manual Rev 04 January 2004 Page 6 Chapter 06 SETTINGS AND ADJUSTMENTS 8 Take out the sampling arm and substitute it with the new one 9 To remount repeat the above steps in inverse order from 7 to 1 Warning After having substituted the sampling arm it is necessary to mechanically align the probe with respect to the wash well and center all the other_positions by following the procedures provided in Section 6 1 1 Alignment and Adjustments 6 4 3 SUBSTITUTION OF THE OPTIC SENSORS 6 1 3 1 Substitution of the OS7 Optic sensor Remove the sampling probe
84. LAMP PWS This board powers the 6V 10W halogen lamp The main device of this circuit is a type LT 1083CP UI integrated stabilizer which under normal operative conditions is regulated via the 1 Kohm potentiometer to 6V for the lamp When the system is in Stand by the lamp is not turned off Instead the voltage is lowered from 6V to 1 2V by the Micro P which acts on the QI transistor via the OFFPL signal This is done in order to not over stress the lamp by turning it on and off frequently ILab 300 Plus Service Manual March 2003 Rev 01 Page 30 Chapter 2 GENERAL DESCRIPTION 2 5 9 SAMPLE RACKS IDENTIFICATION BOARD This board checks that the samples racks are inserted correctly The sole power supply used in the board is Vcc 5V derived from VM 24V that arrives to the board via the J1 connector Racks sensing is carried out via OPB848 type opto sensors U U2 U3 U4 and U These sensors outputs arrive to connector J7 of the Control Panel 30 00342 00 via They exit through the same J1 and go towards J2 of the Stepper Motors Driver Board 30 00188 01 and from here via J4 and J7 enter on J7 and J17 of the Analytical Control Board CPU 30 00195 01 for the management functions performed by the Micro P U1 ILab 300 Plus Service Manual March 2003 Rev 01 Page 31 Chapter 2 GENERAL DESCRIPTION 2 5 10 CONTROL PANEL This board controls the levels of the Rinse Water and Cleaning Solution bottles the closure
85. LLLDLDLDLDLLLLLLLLLLLLDLDLLLDLLLLLLDLLLDLDLDLDLLLLLLLLLDLDLDLDLDLLLLLLLLLLLDLDL
86. Measurement System should perform a two points calibration at the beginning of the sample run If the user is running more than 50 sample a day both cleaning and calibration must be performed after 8 hours by the host analyzer 140 ul of Calibrant B solution are used during two point calibration During two points calibration electrode calibration slopes are transmitted by the module for QC purpose and may be used by the operator to diagnose module performance The slope is defined as Slope Ep Ea log Where CA Calibration A concentration in mmol L Calibration B concentration in mmol L Ea ISE potential developed in Cal A solution in mV Eg ISE potential developed in Cal B solution in mV ILab 300 Plus Service Manual Rev 02 January 2004 Page 9 Chapter 12 Ise Module These slopes are checked by the module s electronic processor and an error code will be transmitted if they are outside the required range Typical slopes are approximately 55mV decade for Na and and 45mV decade for CI Acceptable limit slopes are Slope mV decade Na 50 63 K 50 63 Cl 40 59 ILab 300 Plus Service Manual Range mmol L Serum Urine Na 20 200 20 1000 09 2 20 0 1 50 C 25 200 20 500 02 January 2004 Page 10 Chapter 12 Ise Module 12 8 ELECTRONICS 12 8 1 GENERAL DESCRIPTION ISE module electronics include all pre amplifiers and perform microprocessor control of the fluid pumps
87. Motor A enable Service Manual March 2003 Rev 01 Page 9 Chapter 2 GENERAL DESCRIPTION TAB 1 Micro P Signals Micro I O Buffer Conn Signal P10 Pll P12 P13 P14 P15 P16 P17 20 P21 22 23 24 25 26 27 P30 P31 Signal Function Connector R14 Synchronization 1 micro R R15 Synchronization 2 micro R R16 Synchronization 3 micro 10 Synchronization 1 micro P A PR I PINP Synchronization 2 micro P P Synchronization 3 micro 1 Pump Diluter A 95 PINP2 PINP3 PINP4 5 CA PINP6 Sample door switch d E PINP7 T Cd p ee ee PINP8 Sample button PENA Motor A enable PENB Motor B enable NIS PENC PEND PDIRA IRB PDIRC PPDC PPDD P PUTIO PGI SCLK ADCI ADC2 serial clock rol d WI QO Go Go Go Ni BY GT Nh Cm TM CO ON 5 my BS UU 59 UV d 3 E nN e 1 41 41 1 Oo 2 He 2 cae N Oy Mt any a OH di a0 fac aol ae Q asi fas ii A C N AEE
88. NTERFACE ize Document Number The present drawing is property of AMS A4 3 any use without authorization will be MA 00341 00 prosecuted accordingly to the law Date Wednesday May 30 2001 Sheet 1 of 1 2 Emission zr er r AMS P N 381 00341 EE Analyzer Description Via Forlanini s n c Medical Tiburtina km 18 300 System 00012 Guidonia Roma Description REACTION CHAMBER MOTOR INTERFACE Checked Approved The present drawing is property of AMS any use without authorization will be prosecuted accordingly to the law Drawn Date Scale Sheet Checked Date por Car Drawing Rev pproved Date MA 00341 00 A G 30 05 2001 0805 R1 C2 15M 1 4W 100pF Photodiode 111 S TO99 U5 V 3 C9 6 ER 7 MS 40uF AuF 0805 VS 50 L 7 A R4 5 7K 10K 0805 0805 257 LM4040 SOT 23 IVA C10 0805 12 10uF R2 5 7K 0805 TR1 5K 3296X R3 5 7K 0805 C16 0805 12 9 V 0805 O 125 V VS N GND MC78L05ACD SOP8 C11 AuF 0805 C13 AuF C14 0805 10uF U6 OPA350 508 U1 VS MC78LO5ACD SOP8 10uF NU U3 VIN sie CL AGND yS VREF 6 DOYNG 7225 L5 VD SCLK 28 617 dd ce ES DGND DO
89. OF THE AS NEEDED SERVICE ENG SAMPLING ARM REPLACING OR ADJUSTING THE OPTIC AS NEEDED SERVICE ENG SENSORS REPLACING THE BELT AS NEEDED SERVICE ENG REPLACING A MOTOR AS NEEDED SERVICE ENG ALIGNING THE WASH STATION REACTION AS NEEDED SERVICE ENG PLATE ALIGNING THE CUVETTE BLOCK AS NEEDED SERVICE ENG REPLACING THE PHOTOMETER AS NEEDED SERVICE ENG ADJUSTING THE PHOTOMETER AS NEEDED SERVICE ENG REPLACING THE ELECTRONIC AS NEEDED SERVICE ENG BOARDS CARDS AND THE MECHANICAL MODULES N B the above indicated frequency intervals may vary according to the individual instrument s daily workload ILab 300 Plus Service Manual Rev 03 January 2004 Page 19 Chapter 07 Mantenance 7 13 DECONTAMINATION PROCEDURE Before replacing any instrument parts repairing any defective items or performing any instrument maintenance procedure s the operator or maintenance technician must carry out the below described decontamination procedure of the instrument part s involved in the operation s This procedure can be performed on the entire Analyzer those part s of the instrument subject to possible contamination Material necessary an ESOFENOL solution diluted to 6 60 cc in one liter of distilled water ESOFENOL is an antibacterial and antiviral substance Rubber gloves Mask Lab coat External surfaces and individual parts Spray the solution all over the instrument paying particul
90. OLDER 5 14 ISE FOLDER ILab 300 Plus Service Manual Rev 02 January 2004 19 19 20 20 21 21 22 22 22 22 20 23 24 24 24 25 26 26 26 26 27 27 28 29 29 30 30 32 33 37 2 Chapter 05 DIAGNOSTIC PROGRAM 5 DIAGNOSTIC PROGRAM The diagnostic program enables the operator to perform a complete check of each of the 300 Plus module functions This program has a folder structure with each folder containing functions pertaining to the specific module To launch the program the operator has to click with the left side of the mouse on the Diagnostic area located on the lower right side of the screen of the System Monitor Fig 1 The ILab 300 Plus must be in the stand by state to access this area Fig 1 pn o0000000000000000 o o o 010 0 504040590 lo Cette y Click Here Once the program starts the following screen appears Fig 2 UE an Jerperctres jest User Gabo Beteg Mees Extirg Corb ga e SE Fig 2 Test Optical Switch Sensor Status 0885 4 Status Bar SE pm qun pet The diagnostic program is subdivided into three distinct areas test folders optical switch sensor status O S S S status bar The last two areas are present on every diagnostic window ILab 300 Plus Service Manual Rev 02 January 2004 Page
91. ON CANNULAS CLEANING 5 WASH SOLUTION BOTTLES CLEANING 0 ccc HMM 6 WASH SOLUTION BOTTLES CLEANING 6 POROUS PAD WASHING entes tu e ke REPE RR E ESAE ero 7 POROUS PAD CLEANING PROCEDURE e ee Ry 7 PROCEDURE FOR REPLACING THE POROUS 11 HYDRAULIC CIRCUIT WASHING sis iier nani de Enn eee Pena 12 HYDRAULIC CIRCUIT CLEANING PROCEDURE eA 12 CHANGING THE 5 8 13 PROCEDURE FOR REPLACING THE PERISTALTIC PUMP TUBES 13 CHANGING THE PHOTOMETER 15 PROCEDURE FOR REPLACING THE PHOTOMETER 15 CHANGING THE REACTION 8 0 16 PROCEDURE FOR REPLACING THE REACTION CUVETTES 16 CHANGING THE TUBES KIT sta RR ONE Y SES E RUE Ea se cones 17 PROCEDURE FOR REPLACING THE TUBES 2 1 17 TABLE LIST OF THOSE MAINTENANCE PROCEDURES THAT CAN BE PERFORMED BY THE USER AND OR BY THE MAINTENANCE Espana mementos 18 DECONTAMINATION
92. S 6 2 0 SUBSTITUTION OF THE PHOTOMETER LAMP gt N B Make sure the instrument ILab 300 Plus is turned off before performing this substitution procedure 1 Remove the cover panel of the reaction plate Fig 1 2 Remove the lamp s electrical wires connected to the Lamp Regulator board by loosening the two screws on the M1 connector Fig 4 Unscrew the lamp s fastening screws and remove it from its housing 4 Remount the new lamp repeating the above steps through 1 in reverse order Carry out the electronic adjustment of the photometer as described in Section 6D 2 1 Warning Do not touch the glass portions of the lamp E Halogen Lamp PN 23935001600 4 oz Ma m Lamp s fastening screw c NEL JE a 1 Fig 4 Lamp PWS board PN 23930000400 ILab 300 Plus Service Manual Rev 04 January 2004 Page 33 Chapter 06 SETTINGS AND ADJUSTMENTS 6 2 3 ELECTRONIC ADJUSTMENT OF THE PHOTOMETER Warning make sure that the photometer lamp and the reaction cuvettes are brand new before applying the following procedure 1 Turn on the 300 Plus system first the instrument and then the computer Remove the reaction plate cover Fig 1 2 Launch the diagnostic program select the Plate function and reset by clicking on the appropriate key Make sure that the Home Sensor Reaction Plate window lights up green Place 500 uL of distilled water in cuvette 31 of the reacti
93. S 232C serial connector having the following specifications o Transmission method Asynchronous half duplex o Baud Rate 9600 Bit sec Data bits 8 o Parity Stop bit 1 o Connector 9 pin type D male output from the ILab 300 Plus 5 o 1CF DCD O 2BB RD RTSCA 7 O O 3BA TD CTSCE 8 O RIE O A4CD DTR o s5aBenD Serial connector ILab 300 Plus Service Manual Rev 03 January 2004 Page 2 Chapter 08 Host Communication 8 2 PROTOCOL SPECIFICATIONS This part of Help Protocol Specifications contains information for the laboratory computer and analyzer This exchange of data follows specific ASTM protocols E 1381 95 Standard Specification for Low Level Protocol to Transfer Messages between Clinical Laboratory Instruments and Computer Systems E 1394 97 Standard Specification for Transferring Information between Clinical Instruments and Computer Systems ASTM uses a number of different terms to indicate the way it groups data Field an individual piece of data often referred to as a data field or a data element Record number of logically related data fields grouped together to form one part of a complete message Repeat field a data field of the same type as the immediately preceding it A delimiter separates one instance of a repeat field from the next Component field part of data fi
94. S AND ADJUSTMENTS N B After substituting the reaction plate carry out the mechanical adjustment procedure of the reaction plate as described in Section 6 4 1 Reaction tray interface PN 23300019301 Motor plate interface board PN 23300034100 fa F 42 ix m zeli X Anchored screw Fig 3 Reaction Plate assembly PN 23910006101 Reaction Plate assembly is supplied without Washing Station and Photometer 6 4 3 SUBSTITUTION OF THE OS3 OPTIC SENSOR N B Make sure the instrument ILab 300 Plus is turned off before performing this substitution procedure Remove the reaction plate cover Fig 1 Unscrew the four cross bas fastening screws and remove the cross bar Fig 1 Unscrew the four anchored screws of the reaction plate module Fig 3 gt N Remove the J1 connector and the ground wire from the Reaction Chamber Motor Interface Fig 3 5 Remove the Jl and J14 connectors and the ground wire from the Reaction Plate Interface Fig 3 6 Open the cover panel of the peristaltic pump assembly and disconnect the seven tubes attached to the probes on the washing station 7 Remove the reaction plate from the instrument ILab 300 Plus Service Manual Rev 04 January 2004 Page 46 Chapter 06 SETTINGS AND ADJUSTMENTS 8 Remove the fastening screw from the analysis plate using the special tool supplied by the manufacturer F
95. TION MICRO CONTROLLERS AND BUFFER In order to quickly and most efficiently manage all the devices there are two independent micro controllers U1 and U2 Each sends input and output signals to the relative connectors All signals which begin with the letter P refer to the Micro P U1 while those which begin with the letter R refer to the Micro R U2 The two Micros are HITACHI 8 3048 configured in operative mode 7 single chip Following are some basic performance features elevated speed in carrying out instruction 2 clock cycles at 16 MHz equal to 125 ns to carry out an addition or subtraction operation between 2 registers 128 KBYTES flash memory 4 KBYTES RAM 70 1 0 signals almost all having more than one function plus 8 input only signals are buffered in input or in output the buffer for the T T L signals is 74HC244 the driver for the open collector signals is ULN2803 the operational amplifier LM324 is used for the analogic signals The following two tables list the 78 Micro P and Micro R signals For each the following are specified ILab 300 Plus the name of the signal on the pin of the Micro e g P30 the type I for output O for input the buffer used for the input or the output e g U7 the connector onto which the signal is sent e g J5 the name of the buffer input signal if in input or at buffer output if in output a brief description of functioning e g
96. TP16NEO6L LAMP M P71 J1 16 R26 10K ALFD3 J1 11 D10 47V RXG 2o R O REACTION TRAY HEATER R18 CON2MX C2 750 R23 24K R24 10K ALFD1 J1 19 A ua c5 aep D7 HOME SENSOR OSB J1 17 LEAKP J1 6 R22 2 4K R21 10K Riferimento RPM 60 Description Checked Approved Approved Analyzer Medical System Checked R CORNACCHIA The present drawing is property of AMS any use without authorization will be prosecuted accordingly to the law Tuesday January 09 2001 Emission Come da richiesta di modifica N 60 Description Checked The present drawing is property of AMS any use without Analyzer Via Forlanini s n c authorization will be prosecuted accordingly to the law Medical Tiburtina km 18 300 00012 Guidonia Roma Drawn Description Scale Sheet Checked Date REACTION TRAY INTERFACE __ of 1 Re Drawing Rev Approved Date MA 00193 01 A MOTOR STEPPER BLUE MOTOR STEPPER YELLOW MOTOR STEPPER RED WHITE CON8 NU NO CON8 FILTER WHEEL MOTOR WASHING STATION MOTOR REACTION TRAY MOTOR J3 J4 MICS D 12 0 Emission Rev Description Checked Approved Approved Analyzer EP Medical Checked y R CORNACCHIA itle REACTION CHAMBER MOTOR I
97. TTINGS AND ADJUSTMENTS Protective cover set screw Fig 4 M7 motor fastening screws Fig 5 Fig 6 ILab 300 Plus Service Manual Rev 04 January 2004 Page 15 Chapter 06 SETTINGS AND ADJUSTMENTS M7 Motor assy PN 23100039900 Fig 7 M7 Motor assy PN 23100039900 M7 Motor s belt PN 23935003100 Fig 8 M7 Motor assy PN 23100039900 Fig 9 ILab 300 Plus Service Manual Rev 04 January 2004 Page 16 Chapter 06 SETTINGS AND ADJUSTMENTS 6 1 4 2 Substitution of the M6 Motor N B Make sure the instrument ILab 300 Plus is turned off before performing this procedure Important pay special attention to the Pre heater when removing or servicing the sampling arm 1 Remove the sampling probe 2 Remove the samples and reagents racks protective covers 3 Remove the samples rack and reagents rack 4 Unscrew the four cross bar fastening screws Remove the cross bar by slipping out the Pre heater guide support Fig 1 e Remove the waste tube from the wash well 6 Remove the teflon tube on the diluter head by unscrewing the fastening washer Fig 2 paying special attention to leakage of liquid 7 Unscrew the four anchored screws indicated in Fig 3 unplug the J1 J2 JS JIS and J17 connectors from the Sampling Interface assy unplug the ground wire remove the sampling arm 8 Take the Sampling Interface assy out by unplugging the connectors and unscrewin
98. URE PO 55 01204 00 CHECK WHETHER THE INTEGRATED CHIP TL 71 IS INSTALLED ON THE CONTROL PANEL BD POS U2 see fig 1 AND REPLACE IT WITH THE INTEGRATED CHIP LMC 7101 A or B or 2461 cp Temperature check and adjustment This document describes how to adjust and check the pre heater and plate temperature of the Instrument System 2 Summary CHECK WHETHER THE INTEGRATED CHIP TL O71xxx IS INSTALLED ON THE CONTROL PANEL BD POS U2 see fig 1 AND REPLACE IT WITH THE INTEGRATED CHIP LMC 7101 A or B or TLV 2461 BEFORE APPLYING THE FOLLOWING PROCEDURE e Turn on the system and wait in order to allow the instrument working temperature settlement The warm up time may vary from 30 minutes at about 21 C room temperature up to 100 minutes at about 18 C room temperature ILab 300 Plus Service Manual Rev 04 January 2004 Page 59 Chapter 06 SETTINGS AND ADJUSTMENTS e Calibrate the temperature probe by using the and resistors e Put 300 uL approx of distilled water PRE WARMED at 37 0 37 3 C into the cuvettes 45 and 46 e Measure the temperature into the cuvettes 45 and 46 to get an indication on the plate e Launch the temperatures test from the Temperature folder inside the Diagnostic temperature program in order to measure and or slightly adjust them 3 Special tools KIT FOR TEMPERATURE ADJUSTMENT P N 23550120400 composed b
99. UT UF ADS1250 10uF 0805 SOL16 15 zu 0805 0 Rev itle Size A4 R6 0805 Cis C17 15pF 0805 0805 Emission a ae mm Analyzer a a System Drawn PRE AMPL ADC Document Number MA 00107 00 The present drawing is property of AMS Rev any use without authorization will be 0 prosecuted accordingly to the law Date Friday February 01 2002 Sheet 1 of fe a ee BI a 2 2 5 2 m H 0 00 0 7 swv 8 Description Analyzer 2s ia Forlanini s n c Medical Tiburtina km 18 300 Description Scale Sheet Checked Car Drawing Rev Approved AG INIT L D1 1N4002 U1 M1 INSTALLED ON LEIDSSCE PHOTOMETER 4 t vi vo H3 ADJ R1 120R R2 OR TO REACTION CHAMBER C1 C2 ca Rd Q1 INTERFACE BOARD 100uF 25V B 100uF 25V C3 2N3904 R4 10uF 25V 1K M2 HALOGEN LAMP 6V 10W 0 Emission Rev Description Checked Approved Approved Analyzer Medical Checked Drawn R CORNACCHIA itle PHOTOMETER LAMP PWS ize Document Number The present drawing is property of AMS A4 9 MA 30 0004 00 any use without authorization will be prosecuted accordingly to the law Date Saturday January 12 2002 Sheet 1 of 1 2 P N 9 30 0004 00 2 gt Emission The present
100. Unscrew the four cross bar fastening screws Remove the cross bar by slipping out the rear Pre heater guide support Fig 2 n Remove the waste tube from the wash well 6 Remove the teflon tube on the diluter head by unscrewing the fastening washer Fig 3 pay particular attention to leakage of liquid 7 Unplug connector J7 from the Sampling Interface assy 8 Liftthe teflon washer and expose half ring remove the half ring Fig 4 and Fig 5 9 Remove the teflon washer and the spring Fig 6 10 Remove the Pre heater assembly Fig 7 and Fig 8 making sure that the blocking pin remains in place 11 Remount the new assembly repeating the above steps in inverse order from step 10 to step 1 Note 1 the length of the Pre heater supply cable from the top of the external arm to the intermediate guide must be approximately 23 cm Fig 2 Note 2 when remounting the teflon tube in the diluter make sure that it is inserted correctly 12 Turn on the 300 Plus system instrument and computer 13 Launch the diagnostic program Select the Diluter function and press the Probe Rinse Cycle several times in order to fill the hydraulic circuit with liquid ILab 300 Plus Service Manual Rev 04 January 2004 Page 21 14 15 16 17 18 Chapter 06 SETTINGS AND ADJUSTMENTS Make sure that no liquid leaks from the probe assembly and or the dilutor Make sure that the liquid flows from the p
101. Urine Diluent This is required for urine samples Urine samples must be diluted manually by a factor of 10 to perform urine measurement ILab 300 Plus Service Manual Rev 02 January 2004 Page 8 Chapter 12 Ise Module 12 7 2 REAGENTS CALIBRATION AND SAMPLE PROCESSING The sequence of use of Calibrant A and patient samples during processing is as follows 1 Sample deposited into ISE Module sample port by host analyzer 25 Sample positioned in front of electrodes of Electrolyte Measurement System by the waste pump Sample equilibration and reading occurs during 7 second period Calibrant A pumped into electrode module Calibrant A equilibration and reading occurs during 7 second period Results transmitted to the host analyzer DuC udi p ISE module ready for next cycle Pumpings of a small amount of Calibrant A are performed when the Electrolyte measurement System is in Standby or when it is not being used in the Sample mode This significantly improves the performance of the electrodes The Electrolyte measurement System must always be supplied with power so that pumping can occur Pumping occurs automatically without prompting by the host analyzer beginning 30 minutes after the last sample or calibration was performed During sample processing a volume of 200 ul of Calibrant A solution is used for one point calibration sample wash and cleaning A volume of 120 ul is used for each sip The Electrolyte
102. XB4 TP13 H VPP RESO EXTAL 30 22 425 vec 4 PB6 CS7 RO TP14 lt H GND GND Liy m PB7 DREQ1 TP15 Pat Res 63 ae 4 Po2 RXO MICRO P PIATTO 32 gt VCC 12 5V P90 TX0 P93 RX1 E e P91 TX1 P94 SCLKO ADRMICRO 1 62 S0 F82 JS T E l P92 RXO an P95 SCLK1 P61 BREQ 28 57 1 SETS P93 RX1 P41 g 40 00 POOWAIT et 2 RX2 O 1u 47 50 0 1u R95 POdISCLIKO SIS 2 41 01 GND 2 5 gt 3 P95 SCLK1 ET P42 D2 P53 A19 Ep eiii B P40 D0 ZH 43 03 P52 A18 28 525 di nae P41 D1 ng GND P51 A17 ED P42 D2 P45 2 1 44 04 P50 A16 P27 VMO P43 D3 B1B P45 D5 P27 A15 POR GND 46 06 co minero P26 A14 Ds 44 04 N Us 668000000 9559149599555 L1 145818 45 05 5 gt 470 P46 D6 1 RESA 1 POSR1 3 fe o ocio U1 7 HA H83048 NC vcc VCC DS1233 10 s RESET CX5 QFP100 4 0 1u 4 C14 J7 26 PENA PENB PENC PEND 010 16 8 8 PDIRA 10 PDIRB 11 12 PDIRC 13 14 pDIRD 15 16 BppA 17 18 PPDB 19 20 l BPDC 21 22 l BPDD PCLKA 014 74 244 PCLKB PUTO 1g liyi aa PINP1 P74 RFOTO1 R20 PCLKC PUT10 16 Pal igi PINP2 P75 RFOTO2 R21 PCLKD EML 4122 12 PINPS 22 14 12 1 4 PINP3 P76 6___ R22 RESP
103. Y uoo bo PROP Ee Prata aas Ra 5 12 5 MECHANICAI FBATURBS it tr len e eai cda Cab aca OM HCM 6 12 6 ELECTRODES erret ero tule eto e tot ettet dan ain 7 12 7 FLUIDUMAN AGEMENT dieit i ep rede icem i nde 8 REAGENT USED eire m IU bip i xr beata m R n e tette repete 8 12 7 2 REAGENTS CALIBRATION AND SAMPLE PROCESSING eee 9 12 8 ELECTRONICS uhi v t d teuer e SE 11 GENERAL DESCRIP HON 12 9 MAINTENANCE coreene aa cheandeseusteys 11 I2 I10 TROUBLE SHOOTING GUTDE 12 ILab 300 Plus Service Manual Rev 02 January 2004 Page 1 Chapter 12 Ise Module 12 1 ELECTROLYTE MEASUREMENT SYSTEM 12 1 1 PRODUCT DESCRIPTION Electrolyte Measurement System includes a small simple and reliable ISE module and two peristaltic pumps designed to be mounted within a existing chemistry analyzer The module measures the concentration of Sodium Potassium and Chloride The module contains an integral sample entry port positioned at the top The compact design allows for small sample size and fast operation The modules requires only a 70 ul sample The module housing contains snap in snap out ISE sensor which through simple connectors connect directly to an electronic board in close proximity to the module This eliminates the nee
104. Y OSMOA KLSTB OSMOB KLSTAT NC LSTB EV1 LIQ1 NC KSMP NC LSTAT EV3 KSTAT NC ENC WLST4 NC 5 1 8 3n3 M2A 9 R12 750R CON26A WLST3 NC NC LOCK LIQ2 NC NC MP4 CON26A 100 50 C15 FA1 FA2 FB1 FB2 SDIC403 100 50 C17 m VM C21 SDIC403 KLSTB OSMOB WLST4 NC WLST5 NC KSMP NC KSTAT NC IN8 KLSTAT NC KLRDY OSMOA T PWS CON18A LIQ3 NC LIQ2 NC LIQ1 NC D21 LED GREEN LED GREEN R14 05 TS LM7805 TO R11 750R vcc C4 0 1u 5 LED YELLOW RES CLKB 6 ENB DIRB PDB C6 M1B 3n3 M2B U2 SDIC403 R13 750R D20 LED YELLOW END 06 ULN2803 48 LSTB EV1 RIS3 EV2 16 LSTAT EV3 F a 15 LRDY EV5 NC LOCK 15 05 e NC MP2 L2 Ne MFS NC MP3 11 NC MP4 p VM RIS1 17 RIS2 16 OUT1 15 OUT2 OUT3 13 OUT4 12 OUTS 11 OUT6 VCC ING INS IN4 IN3 IN2 IN1 C14 10uF SPARE CONG 100 50 C16 C20 0 1u AM74 AM74N BM74 BM74N 100 50 C18 R4 1R 2W SDIC403 SPARE BM10 BM10N 14 1R 2W CON7 ON OFF ON OFF ON OFF ON OFF CON12A AM62N AM10N BM62N BM10N AM74N RIS3 EV2 BM74N RIS2 AMS3N BM53N CON10A R16 10K R17 10K M1A M2D R18 10K R19 10K M2A M1D R20 10K R21 10K
105. ab 300 Plus LL Part Number 23500034600 23500034700 23500034701 23500034800 23500034900 23500035000 23500035100 23500035200 23500035201 23500035202 23500035203 23500035300 23500035600 23500035700 23500036500 23500047000 23550120400 23650067800 23900125300 23901003800 23901055800 23905004200 23905004201 23905004300 23905004400 23905004500 23905006300 23905006401 23905007200 23905007300 23905007400 23905007500 23905007800 23910000600 23910001300 23910001601 23910001700 23910001901 23910002200 23910002300 23910002400 23910002801 23910003301 23910006000 23910006101 23910006201 23910006300 Service Manual Service Parts sorted by IL Part Number Description Cable W1 Cable W18 Cable W2 Cable W3 Cable W4 Cable W5 Cable W6 Cable W7 Cable W8 Cable W9 Cable W19 Cable W11 Cable W14 Cable W13 Cable W12 Cable W20 Kit Measurament Temperature Bar Codes kit ILab 300 Tygon Tube M 1 Drying Pad Special Key Cannula 0 Cannula A1 Cannula B Cannula C Cannula D Washing Well Assembly Sampling Probe Reagent Rack 3 from 14 23 Reagent Rack 4 from 24 33 Reagent Rack 1 from 1 4 std ctrl Reagent Rack 2 from 5 13 Bottle level Sensor assembly Washing Station Probe Assembly Cover Lock assembly Stepper Motor Assembly motor with pulley Stepper Motor washing probes Stepper Motor Assembly Photometer Temperature Sensor Horizzontal Home Sensor Assembly filt
106. age 31 Chapter 05 DIAGNOSTIC PROGRAM 5 12 MACRO SETTING FOLDER DIAGNOSTIC This folder allows the user to read the macro present in the ILab 300 Plus To read the macro follow the below procedure Select the micro from which the information will be asked gt Select from the menu sheet Read Macro the number of relevant macro Click with the left side of the mouse on the Read area gt If the Macro requested exists the information will appear in the designated area ILab 300 Plus Service Manual Rev 02 January 2004 Page 32 Chapter 05 DIAGNOSTIC PROGRAM 5 13 CONFIGURATION FOLDER This folder may be accessed only by qualified technical assistant It is necessary for the technical assistant to insert a password to access this folder Test Password Enter Password Wash Station Diagnostic ES 9 93 Jun 03 The Configuration Folder is subdivided into six areas Gap e Backlash Dil e Heater e Diluter Type e Cover Lock SW e Wash Well level Test ILab 300 Plus Service Manual Rev 02 January 2004 Page 33 Chapter 05 DIAGNOSTIC PROGRAM Gap defines the volume in uL of the air bubbles that separate the liquids in the sample column Tipical values are between 10 to 15 Big air bubbles produce the best separation among sample reagent and rinse Better BIB values Small air bubbles produce the best sampling precision Better BIC values It i
107. al Belt for Reaction Plate Bottle 21 Bottle level Sensor assembly Bottle Sensor Cable Bubble Detector Button Kit Cable Cable W1 Cable W11 Cable W12 Cable W13 Cable W14 Cable W18 Cable W19 Cable W2 Cable W20 Cable W3 Cable W4 Cable W5 Cable W6 Cable W7 Cable W8 Cable W9 Cable with Button SW1 sample amp reagent Door Cannula 0 Cannula A1 Cannula B Cannula C Cannula D Caps Kit yellow green red Chloride Electrode Complete Probe Assembly Connection Joint Assembly Control Panel Cover Lock assembly Cuvette Holder Solenoid Diluter 1000 microl Drying Pad Electrode Compression Plate January 2004 Rev 02 ILab 300 Plus LL Part Number 23100020201 23350076100 23935003500 23935003600 23910003301 236135003700 23965003200 23350083900 23010120100 23010122400 2361010122200 2361900125400 23935001600 236101004201 23350083000 23910002400 23910002300 23300041900 23350083600 23935005501 23965002900 23050041300 23350049300 23350083100 23350081800 23915001800 23990090600 23550120400 23965001900 23965004000 23930001400 23930000400 23965003500 236101057200 230101023600 23910006300 230101023200 23350083800 23935004200 236101023000 23050040400 23050044700 23050040300 23910002801 23350083300 23300034100 23100039900 23350083200 Service Manual Service Parts sorted by Description Description Electronic Controller Assy Extractor for connectors Lumbe
108. ar attention to wetting the sampling arm the reaction plate including the cuvettes the racks the instrument chassis Allow the solution to stand for approximately 30 minutes Wipe the solution off the instrument and the various components using a sponge dampened with distilled water Carry out a decontamination of the internal hydraulic circuit 7 14 ANALYTICAL VERIFICATION Verify the performance of the Lab 300 Plus every six months either after the decontamination of the hydraulic circuit or after the replacement of the peristaltic pump tube To verify the instrument performance use two tests ISE tests will be included if available One enzymatic and the other one cholorimetric Use fresh reagents calibrator and controls Run the reagent blank and the calibration if required Perform 20 replicates of two control levels Verify that average values are within the limits reported by the insert sheet of the control serum Verify the C V The coefficient of variation C V should not be greater than what is reported into the Precision section of the relevant method insert sheet ILab 300 Plus Service Manual Rev 03 January 2004 Page 20 Chapter 07 Mantenance 7 15 SWITCH OFF THE SYSTEM STANDBY MODE Select the Shutdown function from the Monitor and then confirm with Yes If requested the instrument will perform ISE cleaning and will empty the fluidics The computer will turn off Do not power off
109. arm and diluter are connected to the board via the J9 710 J11 and J13 connectors The Vertical Home Extemal Arm Home and Internal Arm Home LEDs are placed in series with their power absorption control via the ALFD3 signal connected to J2 Pin 11 that reports information on the Analytical Control Board CPU Information from the leakage sensor enters on the J12 connector is processed by exits on J2 Pin 6 and arrives through J10 to the Analytical Control Board for management The N T C resistor detects the temperature of the pre heater and is connected to J7 on Pins 5 and on Pins 3 and 4 ground These Pins are connected to the U2B amplifier whose output via J2 Pin 25 carries information to the CPU board Analytical Control Board on input AN2 P72 of the Micro R U2 The pre heater heating element is connected via J7 Pins 6 and 7 and is powered by Q1 which is controlled by P W M generated by the Micro R of the CPU Furthermore it can be excluded by switching the 151 relay through Q6 nditioned by the OFFPR signal generated by the CPU ILab 300 Plus Service Manual March 2003 Rev 01 Page 23 2 5 3 1 SAMPLING INTERFACE ASSY INPUT Vertical Home External Arm Home Internal Arm Home Diluter Home NTC LEAK PDIL coming from the CPU OUTPUT Vertical Arm Internal Arm External Arm Diluter Diluter Pump Pre heater LEAK ILab 300 Plus Service Manual March 2003 Chapter 2
110. arm back to the home position Go Reag Go Sample Go Dil Go ISE Go Disp Go Std ILab 300 Plus Brings the arm to the reagent position specified in the sheet menu next to the command Brings the arm to the sample position specified in the sheet menu next to the command Brings the arm to the dilution position specified in the sheet menu next to the command Brings the arm to the ISE position Brings the arm to the dispense position Brings the arm to the standard control position specified in the sheet menu next to the command Service Manual Rev 02 January 2004 Page 10 Chapter 05 DIAGNOSTIC PROGRAM 5 3 3 STATUS COMMAND AREA Send Visualizes the commands sent from the program to the instrument hardware Receive Visualizes the answers of the instrument s hardware to the commands sent by the program Sensor State Indicates the sensor status relative to the arm s vertical axis the internal arm and the external arm 5 3 4 ARM SETTING COMMAND AREA 8 commands Performs the clockwise rotation of the two arms to adjust the position RAB Performs the counter clockwise rotation of the two arms to adjust the position RB Performs the clockwise rotation of the external arm to adjust the position RB Performs the clockwise rotation of the external arm to adjust the position Save Saves the adjustment data Next Brings the arm to the next sample standard dilution or reagent p
111. arm s preheater and reaction plate Diluter Type to select the kind of diluter to be used Each kind of diluter has an individual ratio step per uL Cover Lock SW to disable the check for the closure of the ILab 300 Plus cover ILab 300 Plus Service Manual Rev 02 January 2004 Page 36 Chapter 05 DIAGNOSTIC PROGRAM Wash Well level Test By clicking on the Test button the system performs an automatic verification and adjustment cycle for the liquid level in the washing well A number appears in the box Level that corresponds to the rotation time of the rinse pump in milliseconds that is necessary to maintain the correct liquid level in the washing well The functioning range is between 400 and 700 milliseconds If the washing well is not sufficiently filled a message appears to warn the user to check the hydraulic line If the value taken during the test is different from the previous one it is necessary to click on Save in order to save the new data 5 14 ISE Folder DIAGNUS Tit This folder permits checks and maintenance activity on the ISE Purge fills the hydraulic ISE Module line Maintenance empties the electrodes line for their replacement St By Cycle performs a prime cycle to renew the Calibrant A solution in the electrode line Software Release visualizes the ISE Module Firmware release Cleaning Cycle performs an electrode washing cycle ILab 300 Plus Service Manual Rev 02 Januar
112. ation R A 1 This indicates the cause of termination Code The following codes are valid values for the Analyzer Null or N normal termination Legend R Required D Down Load O Optional U Up Load I Ignored N Never A Always S Sometimes ILab 300 Plus Service Manual Rev 03 January 2004 Page 12 Example Message Terminator Record Layout L Chapter 08 Host Communication Host LIIIN Analyzer System LIIIN 8 8 REQUEST INFORMATION RECORD Q Field Field Title Down Up Max Description and Valid Values Load Load Len 1 Record Type ID A 1 This is a required field that contains Q identifying it as a request 2 Sequence Number A 1 It is always 1 3 Starting Range ID A 31 This field can either be Number ALL to mean all demographics and tests being ordered should be sent to the instrument at this time or can have two components Computer system patient ID No up to 15 characters e Computer system specimen ID No up to 15 characters 4 Ending Range ID N Number 5 Universal Test ID N 6 Nature of Request N Time Limits 7 Beginning Request N Results Date and Time 8 Ending Request N Results Date and Time 9 Requesting N Physician Name 10 Requesting N Physician Telephone Number 11 User Field No 1 N 12 User Field No 2 N 13 Request Information A 1 It is always requesting test Status Codes
113. bal Setting menu in the Diagnostic program Check and in case adjust the probe in all the positions Samples Reagents Standards Controls Diluent Washing Pot see Installation Procedure point 17 to 18 sect 3 6 1 Check the optic system see Sect 6 2 3 Check the temperature see Sect 6 6 1 Check the Backlash see Sect 6 1 6 5 Run two cuvettes washing cycles see Installation Procedure point 19 sect 3 6 1 Perform the WBL for all the cuvettes and checks the results see Installation Procedure point 19 sect 3 6 1 gt Set the methods the control serums standards and reagents Calibrate the methods for testing the ILab 300 Plus Usually one cinetic and one substrate Remember to run the Reagent Blank first if necessary LIH oy LIII ILab 300 Plus Service Manual Rev 02 January 2004 Page 8 Chapter 03 INSTALLATION Run a precision test on the test previously calibrated with the control serum See the analytical performance 3 8 Check the results a 34 SOFTWARE INSTALLATION PROCEDURE Installation Procedure Instrument New 1 Turn on the P C 2 Confirm all the steps in order to complete the installation of Windows 98 Type the number of Product Key It is glued beside the P C 3 Confirm date and time 4 n order to avoid that Windows 98 requires a password at the start up select Start
114. beam inside the cuvette in centered with respect to the sides of the cuvette If not adjust the OS3 optic sensor regulating bar Fig 2 7 To exit the diagnostic program press the Diagnostic key 8 To exit the analyzer program press shutdown key ILab 300 Plus Service Manual Rev 04 January 2004 Page 44 Chapter 06 SETTINGS AND ADJUSTMENTS Reaction Tray PN 23050036600 Analysis plate fastening screw OS3 Opto coupler assy PN 23910002300 Reaction Plate cover Regulating bar 6 4 2 SUBSTITUTION OF THE REACTION PLATE gt N B Make sure the instrument ILab 300 Plus is turned off before performing this substitution procedure Remove the reaction plate cover Fig 1 Unscrew the four cross bas fastening screws and remove the cross bar Fig 1 Unscrew the four anchored screws of the reaction plate module Fig 3 Remove the J1 connector and the ground wire from the Reaction Chamber Motor Interface Remove the J1 J14 connectors and the ground wire from the Reaction Plate Interface pv ch de ped qe Remove the top cover of the washing station using the special wrench supplied by the manufacturer 7 Disconnect the seven tubes attached to the probes on the washing station 8 Remove the reaction plate from the instrument and substitute it with the new one 9 Remount repeating the above steps 7 through 1 in reverse order ILab 300 Plus Service Manual Rev 04 January 2004 Page 45 Chapter 06 SETTING
115. cessary to regulate the electrode housing temperature provided that its environmental temperature does not exceed 38 C However the electrode module should not be subject to changes greater than plus or minus 8 C without recalibrating ILab 300 Plus Service Manual Rev 02 January 2004 Page 7 Chapter 12 Ise Module 12 7 FLUID MANAGEMENT 12 7 1 REAGENT USED The sample is aspirated from a sample cup and dispensed into the sample port at the top of the ISE module The sample is then positioned in front of the sensor using the bubble detector and the Waste Pump Four reagents are needed to operate the ISE module Calibrant Used as wash solution and single point calibrator Calibrant is pumped into the sample port by the Calibrant A pump and then positioned in front of the sensors Calibrant Used as the second point in two point calibration Calibrant B is aspirated from a cup on the analyzer at least once a day or every 8 hours depending upon the laboratory schedule A volume of 500 ul is sufficient for one day s requirements The Calibrant must be placed on the system just before use to prevent a change in values from evaporation Cleaning Solution Should be run once a day to prevent protein built up or at 8 hours intervals if the ISE Module performs greater than 50 samples per day Cleaning Solution may be aspirated from a sample cup 500 ul is sufficient for one day s requirements
116. correct functioning of the instrument Apart from this the security of the operator could be placed at risk 3 2 1 INSTALLATION SITE SPECIFICATIONS Ascertain that the ILAB 300 PLUS system is not exposed to direct sunlight draughts dust or strong magnetic fields In addition please take note of the following conditions required for the location of the installation USE 2 I II DEGREE OF POLLUTION 20s INSULATION CLASS Me INSTALLATION CATEGORY n TEMPERATURE HUMIDITY 20 85 ALTITUDE Max 3000 m LOCATION Shelf or table with a minimum surface of 110x70 cm stable and free of vibration VENTILATION Leave a minimum distance of 10 cm around the instrument to permit air circulation Make sure that the fan situated under the reagent compartment is not blocked by any object 3 2 2 ELECTRIC CURRENT REQUIREMENTS The power voltages to which the instrument is adapted are indicated on the left hand side see fig 1 It must be plugged into a plug of the correct voltage VOLTAGE 90 250 Vac 47 63 Hz 10 FUSES 6 3 Amp T 6 3 x 32 ILab 300 Plus Service Manual Rev 02 January 2004 Page 4 Chapter 03 INSTALLATION NOTE IT IS ADVISABLE TO MAINTAIN THE MAXIMUM STABILITY OF THE ELECTRICAL CURRENT IN THE LABORATORY WHERE THIS IS NOT POSSIBLE OR ASCERTAINABLE USE OF THE FOLLOWING SUPPLEMENTARY DEVICES IS RECOMMENDED ELECTRONIC STABILIZER Used to stabilise the electric voltage in the laboratory Any stabiliser with
117. crew the two fastening screws to make free the support that join the six tubes coming from the washing station probes Disconnect the seven tubes coming from the washing station probes and the air tube inserted on the micro pump P4 coming from the porous pad on fifth probe of the washing station 7 Remove the reaction plate from the instrument 8 Remove the lamp s power supply wires connected to the Lamp Regulator board by loosening the two screws on the 1 connector Fig 4 9 Unscrew the lamp s fastening screws and remove it from its housing 10 Unscrew the four fastening screws on the motor support in order to access the pulley 11 Unscrew the four fastening screws on the motor loosen the pulley fastening screws Fig 3 12 Remove the motor and substitute it with the new one 13 Remount assembly repeating the above steps 12 through 1 in reverse order Warning when tightening the motor pulley fastening screws make sure that the filter wheel is centered with respect to the opto sensor 14 After remounting reseat the lamp and carry out the electronic adjustment procedures as described in Sections 6 2 2 and 6 2 3 ILab 300 Plus Service Manual Rev 04 January 2004 Page 37 Chapter 06 SETTINGS AND ADJUSTMENTS SUBSTITUTION OF THE OPTIC FILTERS Interferential filters Kit PN 23965002900 gt N B Make sure the instrument ILab 300 Plus is turned off before performing this t 10
118. cribed cleaning procedure be performed using instead of only simple distilled water a 5 sodium hypochlorite solution to dampen the gauze and then be repeated using distilled water 7 4 WASH STATION CANNULAS CLEANING PROCEDURE 1 Turn off the Analyzer 2 Place a sheet of paper under the wash station cannulas in order to keep any extraneous material from accidentally falling into the cuvettes 3 Use only lint free paper toweling or gauze 4 Dampen the gauze or paper toweling with distilled water and clean the outside of the cannulas Wipe the cannulas from the top downwards only This is to avoid that any bits of cloth paper or lint fibers accidentally enter the cannulas themselves 5 The manufacturer suggests that once weekly the above described cleaning procedure be performed using instead of only simple distilled water a 5 sodium hypochlorite solution to dampen the gauze and then be repeated using distilled water ILab 300 Plus Service Manual Rev 03 January 2004 Page 5 Chapter 07 Mantenance 7 5 WASHING SOLUTION BOTTLES CLEANING During normal use and over time mold and dust can build up inside the wash solution bottles For this reason it is extremely important that they be periodically washed Said cleaning must be thorough and meticulous in order to insure that every trace of mold or residue be removed How often the bottles must be cleaned depends on their use and on the quality of the distilled water used in
119. cribed in Sections 6 2 3 Warning Do not touch the glass parts of the filter Warning when substituting an interferential filter due to malfunctioning or functional anomalies it is always advisable to substitute the entire set of filters mounted on the instrument ILab 300 Plus Service Manual Rev 04 January 2004 Page 38 Chapter 06 SETTINGS AND ADJUSTMENTS 6 2 PUMP ASSEMBLY 6 3 1 SUBSTITUTION OF THE PUMP ASSEMBLY N B Make sure the instrument ILab 300 Plus is turned off before performing this substitution procedure Unscrew the two knobs to remove the door located on the front elevation of the instrument Fig 1 and the two noticeable screws located on the rear panel Fig 2 to access the washing pump assembly Fig 1 Micro Pump uP4 Assy PN 23050040300 Pumps Assembly Front side 2 Disconnect connectors J1 J2 e J8 from the Hydraulics Interface board rear side Fig 2 3 Disconnect the air tubes from uP4 and the waste tubes coming from the peristaltic pump front side Fig 1 4 Disconnect the three tubes inserted on the EV1 EV4 ed EV6 valves respectively coming from the washing well from the distilled water bottle and from the cleaning solution bottle front side Fig 1 5 Unscrew the four screws which hold the Pumps Assembly Remove it from its site rear side Fig 2 and replace the Assembly with the new one 6 Remount repeating the above steps 5 through 1
120. cuvettes VERTICALLY Moreover be especially careful to not touch the external surface of the cuvettes dedicated to photometric reading Select Plate Second from the pull down menu and then click on OK A dialog box will appear asking Do you want to change the cuvettes requested Click on OK to confirm Remove the cuvettes numbered 31 through 60 by VERTICALLY lifting them out from their housing and then replace them with new cuvettes Make sure to reinsert the new cuvettes VERTICALLY Moreover be especially careful to not touch the external surface of the cuvettes dedicated to photometric reading Carry out a WBL cycle Check system efficiency by comparing the WBL values and the test results obtained against the laboratory s quality control values ILab 300 Plus Service Manual Rev 03 January 2004 Page 16 Chapter 07 Mantenance 7 11 CHANGING THE TUBES KIT Over time and through normal use the tubes become worn The manufacturer suggests that the tubes be replaced at least once a year These tubes are located behind the panel situated behind the wash station 7 11 1 PROCEDURE FOR REPLACING THE TUBES KIT 1 2 3 4 5 6 Turn off the Analyzer Remove the panel located behind the wash station Replace the tubes following the indications provided in the hydraulic diagram SI 00457 00 Turn on the Analyzer and wait until the instrument has reached its proper operating temperature Carry
121. d for cables and maximizes noise immunity Samples and calibrators are positioned within the module by two snap in snap out peristaltic pump cassettes The waste pump positions the sample in front of the sensor for measurement After sample measurement a calibrant wash solution is pumped in front of the sensor for a single point calibration Provision for two point sensor calibration and cleaning are made through use on the analyzer sample tray which serve as reservoirs for the second calibrator and cleaning solution The module is completely self contained All sample and calibrant positioning within the module is controlled by an integral microprocessor which assure reliable electrode operation and maximum lifetime ILab 300 Plus Service Manual Rev 02 January 2004 Page 2 12 2 ELECTROLYTE MEASUREMENT BENEFITS Features Integral Sample Entry port Small Sample Size Electrodes Mounted Close to Electronics Sample Port Adjacent to ISE Sensor Rapid Operation 30 Sec Cycle Time Easy to access sensors No membranes Easily accessed pumps Two bubbles detectors Two point calibration One point calibration with every sample Maintenance free electrodes 6 month or 10 000 sample warranty Disposable reference electrode no addition of filling solution required ILab 300 Plus Service Manual Chapter 12 Ise Module SYSTEM FEATURES AND Benefits Minimal Sample Carry Over 70 ul Minimal electronic noise improves precision Minimal Sam
122. d remove the base as shown in Fig 12 10 Remove the motor fastening screws and loosen its pulley screws Fig 14 11 out the M5 motor and substitute it with the new one 12 Lift the pulley to approximately 0 5mm from its upper limit and tighten its screws Fig 14 13 Push the motor outward as shown in Fig 9 and holding it in this position so as to maintain the belt in tension tighten the motor fastening screws 14 Tighten the base support screws Fig 11 15 To remount repeat the above steps in inverse order from 8 to 1 Warning Do not tighten the protective cover s set screw as this could result in mechanical malfunction of the sampling arm s vertical movement Fig 4 Warning After having substituted the motor it is necessary to mechanically align the probe with respect to the wash well and center all the other positions by following the procedures rovided in Section 6 1 1 Alignment and Adjustments M5 Motor s belt PN 23935003100 ILab 300 Plus Service Manual Rev 04 January 2004 Page 20 Chapter 06 SETTINGS AND ADJUSTMENTS 6 1 5 PRE HEATER AND LEVEL SENSOR 6 1 5 1 Substitution of the pre heater and level sensor assembly N B Make sure the instrument ILab 300 Plus is turned off before performing this procedure 1 Remove the sampling probe 2 Remove the samples and reagents racks protective covers 3 Remove the samples rack and reagents rack 4
123. d valve near module is not activated during the read portion of the cycle Component failure on module board Replace the board May occur when new sensor Purge the Cal A and recalibrate or new bottle of Cal A is the module installed on system Air in Sample Insufficient sample pipetted a Host instrument must into module sample port deliver 70 ul Increase dispensed volume b Insufficient sample in sample cup for all tests programmed Sample Pumps not connected properly properly Pump tubing obstructed or tubing length is excessive Air in Sample and Cal A Sensors are not properly compressed Check compression plate spring and seal Ensure that all sensor and o rings are in place Use Cleaning procedure sensor flow path CLEN for module Disassemble module and clean or replace sensor with plugged flow path 4 Waste Pump failure Replace the waste pump ILab 300 Plus Service Manual Rev 02 January 2004 Page 13 Chapter 12 Ise Module Air in Cal B and in Cal A 1 Cal and Cal A Sensors are not properly segmented with air compressed Check compression plate spring and seal b Ensure that all sensor and o rings are in place Use Cleaning procedure CLEN for module b Disassemble module and clean or replace sensor with plugged flow path 3 Waste Pump failure Replace the waste pump sensor flow path
124. e by clicking on it 1 Mu Wow Click on ALYSSWXX A20 file or ALYSSWXX A20 file if it is located on a floppy disk in the folder in order to select it on the File name section and click OK Click on Activate key and wait until the Micro 1 programming operation finishes When finished a window named Report will appear click OK Exit by clicking on Quit key and click OK to confirm Click on the Write Confirm red button to transfer the setting data on the Micro 1 When the Write Confirm red button disappears it means that the data transfer has been completed Short circuit pins 1 and 2 of the J4 connector on the Analytical Control Board Select Arm Micro 2 and click on the Read Down Load key ILab 300 Plus Service Manual Rev 02 January 2004 Page 11 Chapter 03 INSTALLATION 7 A window named Write Log with When the downloading is completed press Write Confirm key will appears Click OK 8 Click on File key and select 20 on the list files of type by clicking on it 9 Click ALYSSWXX A20 file or aNMALYSSWXX A20 file if it is located on a floppy disk in the folder in order to select it on the File name section and click 10 Click on Activate key and wait until the Micro 2 programming operation finishes 11 When finished a windo
125. e other positions by following the rocedures provided in Section 6 1 1 Alignment and Adjustments Anchored screws Sampling Interface Assy OS6 Opto coupler assy PN 23300019201 PN 23910002300 ILab 300 Plus Service Manual Rev 04 January 2004 Page 10 Chapter 06 SETTINGS AND ADJUSTMENTS 6 1 3 2 b Substitution of the OS5 Opt coupler a b d e Carry out Steps 1 through 6 as indicated in Section 6 1 3 Substitution of the OS6 and OS5 Opto sensors Remove the screws which fasten the opto sensor support and take out the entire assembly Fig 7 Unplug the J9 connector from the Sampling Interface assy remove the optic sensor fastening screws and substitute it with the new one Pay particular attention to the spacer washers placed between the opto sensor and the support Fig 8 To remount repeat the above steps in reverse order from c to a and then from 6 tol in Section 6 1 3 2 OS5 Opto coupler assy Spacer washers PN 23910002400 ILab 300 Plus Service Manual Rev 04 January 2004 Page 11 Chapter 06 SETTINGS AND ADJUSTMENTS Warning Do not tighten the protective cover s set screw as this could result in mechanical malfunction of the sampling arm s vertical movement Fig 2 N B make sure that the distance between the top edge of the wash well and the tip of the probe is 2 0 0 5 mm Warning After having substituted the opto sensor it is necessary
126. e temperature probe tip through the small door for cuvettes replacement See fig 2 To avoid the temperature probe damage to be sure its wires do not interfere with the reaction plate rotation ILab 300 Plus Service Manual Rev 04 January 2004 Page 63 10 11 12 13 14 Chapter 06 SETTINGS AND ADJUSTMENTS 1 Verify that the temperature probe or others tools are correctly positioned so to avoid their interference with the moving parts of the instrument During this procedure step in fact the Sampling arm the washing Station and the Reaction Plate will become active Select Temp Test Run in the Temperature Folder inside the Diagnostic program By pressing START the system will sample seven reaction cuvettes in sequence At the end of the sampling cycles the main cover will be unlocked ae a Wait 10 minutes open the main cover and the small door for cuvettes replacement Measure and take note of the cuvettes temperature starting from the third up to the first cuvette by dipping and gently shaking the temperature probe into the liquid 6 At the end of the measurements press WASH The system is ready for a new cycle Note 2 In this case cuvettes 1 through 3 can give a good indication of the reaction plate temperature 7 If necessary modify the value in the PLATE parameter field Configuration Folder in the Diagnostic Program by taking into account that 7 COUNTS CORRESPOND TO ABOUT 1 C After any
127. ecke XV ate System TIAM 17 03 2003 Treatment e present drawing is property o any use withou Approved Date 22 18 03 2003 Description Scale Sheet 50 0013 01 MODULO ISE Finish Drawing Rev ISE MODULE KIT 65 0019 00 O 125V Q3 U12 74HC244 U19 74HC244 1Y2 1Y3 1 4 2Y1 2Y2 2Y3 1 2 3 4 5 x1 AVCC 125V Q2 R1 2k2 Di LED R2 1 16M PNP PMD2 XTAL EXTAL VM O gt 125V Q4 4 092 R6 1K PNP RVPP x mxxxx aae zd ui C3 d C6 ISAR FSGS ARRS 10uF R8 500R Ld O92 R9 P 12p 0 lu EPMD2 PEVPP PMD2 500R lt VCC 5 50220080 MD2 gt PBO TIOCA3 TP8 9059555569900946004 2 MD1 gt VCC Us PB1 TIOCB3 TP9 Oo OSEE secs see MDO Be ca 2 4 EEEESozo 9999 tkt 66 H3 ISE LM2940C aaa PB2 TIOCA4 TP10 535858580 P6G LWR 22 568 n PBO TIOCA3 TP8 PB4 PB3 TIOCBA TP11 59 P65 HWR p64 R900UT RB2 PB1 TIOCB3 TP9 6 1 PBA TOCXAMITP12 SFEER P64 RD 2 53 1 25 RBS PB2 TIOCA4 TP10 SES L PBS TOCXBA TP13 5559952 P63 As 69 2 259 PB3 TIOCBA TP11 PB7 2 PB6 CS7 RO TP14 pn Be Be VCC 22 1dT1A CC 3 R14 RBS PB4 TOCXA4 TP12 SUPP 2 PB7 DREQ1 TP15 XTAL S2 S EOS an CBOE RBS PB5 TOC
128. ector J4 which conditions the internal switching logic intervention threshold to 0 8 volts if it is kept at a high logic level and 0 5 volts if at a low logic level OPEN COLLECTOR DRIVERS Two integrated circuits are present on the board U6 and U7 ULN2803 and constitute an open collector interface for 16 signals 10 of which come from the control board UT1 UT10 via J4 with their outputs connected to J2 6 gathered via J5 and placed in output on J6 These outputs are used to pilot various types of power devices continuous current motors solenoids electrovalves etc ILab 300 Plus Service Manual March 2003 Rev 01 Page 20 Chapter 2 GENERAL DESCRIPTION 2 5 2 1 TA 8435 H INTRODUCTION TA 8435 H controls the PWM for setting the current of the Stepper Motor windings to a constant value The device is an integrated circuit for micro step piloting used in order to have an efficient and low vibration control over the Stepper Motors MICRO STEP PILOTING TA 8435 H controls a Stepper Motor in micro steps with a maximum resolution of 1 8 of a step The current levels of the A and B phases are regulated in micro steps within the integrated circuit in such a manner that the size and rotation angle of the vector between the micro steps remains constant When the clock signals are placed in input CK2 the Stepper Motor will rotate in micro steps CONTROL OF PULSE WIDTH MODULATION AND OUTPUT CURRENT Output cur
129. ed against the laboratory s quality control values ILab 300 Plus Service Manual Rev 03 January 2004 Page 12 Chapter 07 Mantenance 7 8 CHANGING THE PERISTALTIC PUMP TUBES The manufacturer recommends that the Peristaltic Pump tubes be replaced every six months Said frequency may vary depending on the workload of the individual laboratory The quality and reliability of these tubes is fundamental to a correct emptying of the cuvettes 7 8 1 PROCEDURE FOR REPLACING THE PERISTALTIC PUMP TUBES 1 Turn off the Analyzer 2 Remove the panel located behind the wash station Fig 1 3 Unhook the hinged guide by lowering and rotating the guide s blocking bracket to the left Fig 2 4 Once the hinged guide has been removed pull the tubes out of their relative nipples je IIE 4 Mc no 9 dd Peristaltic Pump Wash station pumps assembly 5 Insert the new tubes into their relative nipples 6 Position the tubes around the peristaltic pump rotor 7 Close back the hinged guide ILab 300 Plus Service Manual Rev 03 January 2004 Page 13 Chapter 07 Mantenance 8 Manually rotate the peristaltic pump rotor clockwise and check to make sure that the tubes are correctly positioned inside the guide 9 Turn on the Analyzer and wait until the instrument has reached its proper operating temperature 10 Have the instrument carry out a Wash cuvettes cycle and then a WBL cycle Check system effici
130. een designed to be a generic control of input output governed by an external C P U or by an internal PC board based platform in light of possible different future instrument configurations CIRCUIT DESCRIPTION The following description refers to the SE 00195 01 Rev C electrical wiring diagram POWER SUPPLY e The main power supply VM 24V filtered by C10 and C12 is taken up via connector 16 and used to generate the 5 volts moreover it is brought back on connectors J9 and J10 to 25 pins e The 5V is obtained through U4 LM2575 the Schottky D5 diode the L1 inductance and condensers C14 and C15 the entire circuit makes up a step down converter from 24V to 5V with 1 Ampere of current e Said power supply is brought back on connector J6 forecasting the possibility that it could come directly from an external power source in this case the step down components are not mounted with the exclusion of the C14 and C15 condensers e A second power supply 12 5V filtered via C9 and is taken up via connector J6 in addition to being brought back on connectors J9 and J10 to 25 pins and on connectors J13 and J14 to 10 pins and utilized to generate the 12V for the two flash memories inside the two Ul and U2 microprocessors and the AVCC AVCC 5V used for the operational U23 and U24 and also for the two microprocessors internal A D converters ILab 300 Plus Service Manual March 2003 Rev 01 Page 8 Chapter 2 GENERAL DESCRIP
131. eld that might contain more than one piece of data The default communication configuration for the Analyzer is the following 9600 N 8 1 ASTM uses record types that are common and familiar to all laboratory personnel It uses the following record types Header Record H contains identifying information about the sending station conventions that the device uses for field recognition and the date and time of send station transmission Patient Record contains patient information and identification number Test Order Record O contains information about the assay or requests themselves and includes other data Result Record contains information about the outcome of individual tests for individual patient and follows a sample program record The results contain the actual measurements derived from the test and a comparison of the individual result to certain ranges specified as norms for the laboratory ILab 300 Plus Service Manual Rev 03 January 2004 Page 3 Chapter 08 Host Communication Message Terminator Record L although the ASTM protocol supports three additional record types a Request for Information Record a Scientific Record and a Manufacturer s Information Record the Analyzer is not implementing these in the first release and will ignore them Request Information Record Q is used by either clinical instruments or computer systems for a remote request for information fr
132. embly Washing Well Assembly January 2004 Rev 02 APPENDIX Washing Station s cycle WASHING STATLON PUMPS 15 00406 00 MP2 u Pump Pump Channel 1 post H O Cleaning Channel 2 ant Peristaltic pump waste solution WASHING STATION PROBES 9 10 0006 00 Rate of flow of the Peristaltic Pump 1000ul second LLLLLLLLLLLLLLLLLLLLLDLLLLLLLLLLLLLLELLLLLLLLDLLLLLLLLDLLLLLLLLLLLLLLDLLLLLLLLLILILLILL Probe N 1 ON EVI empitying of the channel of the Probel is enabled uP4 ON uPump Probe 5 0 ON peristaltic pump remains ON until the end of the cycle Washing Station goes down 570mS Liquid into the cuvette is aspirated Aspirated and dispenced 400uL 50uL of Cleaning solution While empitying with the Peristaltic Pump Wait 100mS Aspirated and dispenced 400uL 50uL of Cleaning solution While empitying with the Peristaltic Pump Wait 300mS Washing Station goes up 570mS OFF empitying of the channel of the Probel is disabled uP4 OFF uPump 4 ProbeS 0 OFF Pump peristaltic Cycle lasts 3790mS used 800ul 100ul of Cleaning solution PAS AS FAS HS K K K K K K K K K K K
133. emove the samples and reagents protective covers Fig 1 2 Remove the samples rack and reagents rack 3 Remove the teflon tube on the diluter head by unscrewing the fastening washer Fig 2 paying particular attention to leakage of liquid 4 Unscrew the four anchored screws indicated in Fig 2 unplug the J6 J8 and J13 connectors from the Sampling Interface assy Fig 3 5 Remove the diluter module from the instrument 6 Unscrew the two fastening screws on the electro valve take it out and substitute it with the new one Fig 2 7 To remount repeat the above steps in reverse order from 6 to 1 8 After mounting the new electro valve carry out the check procedure for mechanical functioning as described in Section 6 1 6 4 6 1 6 4 Diluter module Check procedure for mechanical functioning 1 Turn on the 300 Plus system instrument and computer 2 Remove the protective cover of the samples and of the reagents Fig 1 3 Launch the Diagnostic program select the Diluter function and click on Home field Make sure that the Home Sensor Dil shows green 4 Select aspiration and then dispense volumes between 3 to 500 microliters clicking on the appropriate windows 5 sure that the diluter both aspirates and dispenses as requested and that there is no leakage of liquid from the hydraulic connections 6 Exit the Diagnostic program by pressing the Diagnostic key 7 Exit the analyzer program p
134. ency by comparing the WBL values and the test results obtained against the laboratory s quality control values 11 Make sure that there is no leakage and then close back the panel Fig 2 Hinged Guide Tubes to be replaced ILab 300 Plus Service Manual Rev 03 January 2004 Page 14 Chapter 07 Mantenance 7 9 CHANGING THE PHOTOMETER LAMP The manufacturer suggests that the lamp be replaced after approximately 2000 hours of use or one year Figure 3 illustrates the photometer lamp its support base and its power supply wires There is a small hole on the lamp base useful for its mechanical alignment The lamp is mounted on the photometer which is located on the right hand side of the reaction plate 7 9 1 PROCEDURE FOR REPLACING THE PHOTOMETER LAMP 1 Turn off the Analyzer 2 Remove the reaction plate cover 1 Disconnect the power supply wires from the Lamp Regulator Board by loosening the clamp screws on the M1 connector Fig 4 4 Unscrew the lamp s fastening screw and remove the lamp from its housing Fig 4 5 Replace the old lamp with a new one making sure that the pin is correctly inserted in the alignment hole Fig 4 Remount the assembly by repeating the above steps 4 through 1 in inverse order 6 Turn the Analyzer on and wait until the instrument has reached its proper operating temperature 7 Carry out a WBL cycle Check system efficiency by comparing the WBL values and the test results obta
135. eping the cup below the probe the probe must be submerged into the cup so that it can aspirate the 300 MicrL of liquid click on Aspirate ASP 13 Remove the cup Be careful do not touch the tip of the probe Any movement of the probe can affect on the adjustment 14 Set up the cursor at 1 MicroL 15 Look carefully at the tip of the probe while selecting DISP 16 Count the number of click with the DISP button before a drop of liquid appears A small bubble 17 The number of clicks minus 1 is the value that must be set in Backlash DIL in the 18 Configuration folder 19 Save the new value ILab 300 Plus Service Manual Rev 04 January 2004 Page 29 Chapter 06 SETTINGS AND ADJUSTMENTS Reagents protective cover Samples protective cover Micro pump assembly PN 23910002801 Fig 2 Diluter Module Anchored screw Fig 3 ILab 300 Plus Service Manual Rev 04 January 2004 Page 30 6 2 Chapter 06 SETTINGS AND ADJUSTMENTS OPTIC ASSEMBLY 6 2 1 SUBSTITUTION OPTIC ASSEMBLY gt 10 11 12 13 N B Make sure the instrument ILab 300 Plus is turned off before performing this substitution procedure Remove the cover panel of the reaction plate Fig 1 Unscrew the four cross bar fastening screws and remove the cross bar Fig 1 Unscrew the 4 fastening screws on the reaction plate assembly Fig 2 Remove the 11 J2 connectors and the ground wire from the Reaction Chamber M
136. er all the other positions by following the procedures provided in Section 6 1 1 Alignment and Adjustments N B the following check is valid only for the OS7 optic sensor Verification of the correct positioning of the OS7 optic sensor Set the Samples position at 16 If it is not possible to obtain an exact centering due to mechanical end of run move the OS7 optic sensor to the left After having mechanically aligned the optic sensor center all the other positions by following the procedures provided in Section 6 1 1 Washing Well assembly OS7 Opto coupler assy PN 23905006300 PN 23910002300 Protective cover set screw ILab 300 Plus Service Manual Rev 04 January 2004 Page 8 Chapter 06 SETTINGS AND ADJUSTMENTS Fig 4 6 1 3 2 Substitution of the OS6 and OS5 Opto sensors N B Make sure the instrument ILab 300 Plus is turned off before performing this substitution procedure In order to arrive at the OS6 and OS5 Opto sensors it is necessary to remove the arm assembly from its housing Unplug connectors J9 and J10 from the Sampling Interface assy disconnect the wash well hydraulic tube and the teflon tube on the diluter Loosen the four anchored screws When removing the sampling arm be extremely careful to not damage the pre heater The following steps from 1 to 6 are to be carried out regardless of which opto sensor is being substituted OS6 or OS5 1 Remove the sampling probe f
137. er wheel reaction plate washing station Home Sensor Assemby vertical Micro Pump Assembly Probe rinse Front Panel Switch assembly Cuvette Holder Solenoid Reaction Plate Assy Complete Probe Assembly Level Sensor and Pre heater Assy January 2004 Rev 02 3 ILab 300 Plus LL Part Number 23915001800 23915002000 23915002400 23930000400 23930001400 23935001600 23935002201 23935003100 23935003200 23935003401 23935003500 23935003600 23935004000 23935004100 23935004200 23935005501 23950001000 23950003000 23965001900 23965002701 23965002900 23965003100 23965003200 23965003500 23965003601 23965003700 23965004000 23990090100 23990090600 23650022702A 23AS620005 23C10048300 236101004201 2361010122200 236101023000 236101023200 236101023600 236101057200 236135003700 2361900125400 23235001800 23F 35001900 23F50002000 Service Manual Service Parts sorted by IL Part Number Description Ise Module Arm Assembly Refrigerated Reagent Rack assembly Lamp P W S Board Label Index Board Halogen Lamp Reaction Plate Heather Belt arm vertical Belt for Reaction Plate Power Supply Fluidic Valve 2 ways W P Fluidic Valve 3 ways W P Bar Code Reader Bottle 21 Main Power Socket Interconnecting Serial Cable 9 Pin 5m Cable Cable with Button SW1 sample amp reagent Door kit Ise Module Tubes Kit Interferential filters Kit Photometer Reaction Cuvette 60 pieces Fuse Holder Kit Lamps kit 5
138. erface Fig 2 Loosen the two flywheel and motor joint screws Fig 3 Unscrew the four fastening screws on the motor support and remove it Fig 3 Unscrew the four fastening screws on the motor substitute it with the new one Fig 3 Xo 595 uso DON CAS PEDEM VS URS Remount repeating the above steps 8 through 1 in reverse order After substituting and remounting carry out the mechanical adjustment functional check procedures as described in section 6 5 4 ILab 300 Plus Service Manual Rev 04 January 2004 Page 52 Chapter 06 SETTINGS AND ADJUSTMENTS 6 5 4 WASHING STATION MECHANICAL ADJUSTMENT AND FUNCTIONAL CHECK 6 5 4 1 Washing Station Horizontal Alignment 1 Turn on the ILab 300 Plus system and launch the Analyzer program 2 Launch the diagnostic program and select the Plate function Reset by clicking on the appropriate key Make sure the Home Sensor Reaction Plate window lights up green 3 Select the Washing function Reset by clicking on the appropriate key Make sure the Home Sensor Washing Station window shows a green light 4 Select several times Home and Down by clicking on the appropriate keys Make sure the washing station probes enter the reaction cuvettes freely and totally unhindered Pay particular attention to the drying pad placed on probe number five If the drying pad does experience any friction whatsoever loosen the two fastening screws on the bottom
139. ese parameters are saved in two different files in the Analyzer folder The two files are Micro_arm ams and Micro_plate ams e Download which make possible both to open the files Micro Arm ams and Micro Plate ams and write the system parameters previously saved into the micros This is useful when a replacement of the Analytical Control Board is necessary The files with the system setting parameters can be reloaded The files Micro Arm ams and Micro Plate ams are automatically update every time the Diagnostic is selected or during the Diagnostic shutdown ILab 300 Plus Service Manual Rev 02 January 2004 Page 13 Chapter 03 INSTALLATION Modules Must be selected before the Upload and or Download ex If you want to save the Arm parameters select ARM and press UPLOAD ex If you want to save the Plate parameters select PLATE and press UPLOAD From file to Micro select Arm and press Download BOX PARAMETERS then select Plate and pressDownload BOX PARAMETERS At the Micro Arm are linked the arm position parameter the pre heater and the diluter At the Micro Arm are linked the temperature of the reaction disk and the setting of the temperature adjustment s probe ILab 300 Plus Service Manual Rev 02 January 2004 Page 14 OPTION AL courue Litt m s LLL enr assy 00202 01 8 50 0035 01 i PUNP 10 0026 1 50 00347 91 CWE S6 00352 03 W19
140. every time a rack is removed either for servicing or substitution N B Make sure the instrument ILab 300 Plus is turned off before performing this procedure 1 Open the front panel and remove the reagents racks 2 Remove the top cover of the reagents Fig 1 3 Loosen the four fastening screws on the reagents racks holder Fig 2 4 Replace the top cover of the reagents Place empty reagents cups in the first and last position of the racks and reinsert the racks e Align the holes of the reagents containers with those of the top cover of the reagents 6 Once again remove the top cover of the reagents remove the racks and tighten the fastening screws of the reagents racks holder 7 Reposition the racks and replace the top cover of the reagents 8 Close the front panel top cover of the reagents Reagents racks holder ILab 300 Plus Service Manual Rev 04 January 2004 Page 70 Chapter 07 Mantenance CHAPTER 07 7 1 7 2 T9 7 4 TS 7 5 1 7 6 7 6 1 7 6 2 7 7 7 7 1 7 8 7 6 1 7 9 7 9 1 7 10 7 10 1 7 11 7 11 1 7 12 7 13 7 14 7 15 MAINTENANCE INDEX MAINTENANCE e slow ii tues esos ev take se EORR eva M ERE scans 2 PREVENTIVE MAINTENANCE eer DEL esas 2 LIST OF PARTS SUBJECT TO WEAR AND 4 SAMPLING PROBE CLEANING 5 WASH STATI
141. f liquid in the washing pot 23 Home all the parts of the instrument by selecting the folders in the diagnostic program Check all the sensors looking at the color at the bottom of the screen 24 Select the Global Setting folder and check the probe in all the positions 25 Exit the Diagnostic program Select Start green arrow and run a washing cycle and a Water Blank Level WBL Check the result NOTE when the setting is completed save the new Analyzer MDB file To access the Windows program logout the ILab 300 Plus software by typing Ctrl Alt 5 Ctrl Alt Shift with Software Revision up to 1 0 7 Respond YES when the system prompts System Shutdown is Turned Off Select Shutdown then OK Make a copy of the Analyzer MDB file in the Analyzer folder either in a different folder or on a floppy disk I nstallation Procedure Upgrade I mportant With the software version 1 x x the system requires at least the Firmware 5 7 1 Exit the ILab 300 Plus software by pressing first Ctrl Alt Shift Ctrl Alt 5 if already Version 1 0 8 Select Shutdown 2 Insert the CD Rom ILab 300 Plus Ver 1 X X Wait the program starts In the mask 300 Plus rel 1 0 8 Multilanguage Setup click on Next There are three choices Complete Upgrade and Service Select Upgrade Follow the steps as required The system will install the new MasterSoftware and the new MasterHardware Select YES when is asked if maintain
142. finger and make sure that the level sensor LED on the Sampling Interface assy turns on approximately one second when the probe is touched Fig 9 Level Sensor and Pre Heater assembly PN 23910006300 ee AERA n PITTS A Sensor Level LED 23 i mo s Fig 9 Sampling Interface assy PN 23300019201 ILab 300 Plus Service Manual Rev 04 January 2004 Page 25 Chapter 06 SETTINGS AND ADJUSTMENTS N B during automatic functioning routine analysis every time the sampling probe dips into any liquid whatsoever the Level sensor LED on the Sampling Interface assy will turn on for approximately one second We advise that you never allow the level sensor to operate when the solution quantity is less than 290 ul a b d e g h i k In order to more specifically verify the correct level sensing functioning proceed as follows Place cup containing liquid in the first samples rack position nr 1 Volume gt 290 ul Launch the diagnostic program Select the Arm function and press the Go Sample key in order to allow the probe to move into the position corresponding to the sample cup In the window next to the Go Level enter the maximum descent of the probe e g 500 Select Go Level and make sure that the probe drops down into the cup until it senses the liquid In the window to the right of the Go Level key the level reached by the probe will appear ex
143. first and retest If solutions still low replace Cal A and retest 3 Deterioration of sensing Replace problem sensor and test electrode High Slope 4 Air bubble on Reference Remove electrode tap to Na or K gt 63mV decade Electrode membrane dislodge bubble replace and Cl gt 60 mV decade recalibrate electrode retest electrodes retest or liquid higher than 37 necessary change location Single electrode electrode 2 Electrical noise spike from a Check that motor environmental source solenoid valve near is not activated during the read portion of the module cycle Component failure module board Replace board Noise Error Flag Multiple electrodes that motor or solenoid valve near module is not activated during the read portion of the module cycle Component failure module board Replace board ILab 300 Plus Service Manual Rev 02 January 2004 Page 12 Chapter 12 Ise Module Drift Error Flag 1 Deterioration of sensing Replace problem sensor and Single electrode electrode test 2 May occur when new sensor Purge the Cal A and recalibrate or new bottle of Cal A is the module If the sensor is new installed on system it may initially drift as it rehydrates over the course of 15 minutes Drift Error Flag 1 Deterioration of Reference Replace reference electrode and Multiple electrodes electrode retest 2 Electrical spike from a Check that motor or environmental source solenoi
144. from its housing Remove the samples and reagents racks protective covers Remove the samples rack and reagents rack Joe Wee nbus Unscrew the four cross bar fastening screws Remove the cross bar by slipping out the Pre heater guide support Fig 1 Loosen the protective cover s set screw Fig 2 and lift it 6 Remove the fastening screws from the optic sensor support unplug the J11 connector from the Sampling Interface assy and take out the entire assembly Fig 3 7 Remove the fastening screws from the optic sensor itself and substitute it with the new one 8 To remount repeat above steps in inverse order from 7 to 1 N B when remounting the optic sensor make sure to center it with respect to the slots as shown in Fig 4 N B due to the fact that it may be necessary to further adjust the positioning of the optic sensor screw down the cross bar and the protective cover only after having made sure that the sampling arm functions correctly by carrying out the procedure described in Section 6 1 1 ILab 300 Plus Service Manual Rev 04 January 2004 Page 7 Chapter 06 SETTINGS AND ADJUSTMENTS Warning Do not tighten the protective cover s set screw as this could result in mechanical malfunction of the sampling arm s vertical movement Fig 2 Warning After having substituted the optic sensor it is necessary to mechanically align the probe with respect to the wash well and cent
145. fy matters in the event of any future claims for damages Upon arrival of the crate s box take out the LIASYS N delivery note and make sure that all the items the packing list are included in the crates S N and are undamaged Make sure the series P JN number on the delivery note packing list corresponds to that impressed on the plate on 7 3 nalyzer the right side of the instrument J Open the crate s box from the top and very carefully take out the instrument the computer and accessories MAKE SURE THAT THE UNPACKING IS CARRIED OUT BY TWO PEOPLE Do not discard the delivery crate s box or the packing material until the correct functioning of the instrument has been ascertained Remove all the items from the crate s box very carefully Remove the adhesive tape from the cover of the samples and reagents housing from the front panels and from the samples and reagents racks ILab 300 Plus Service Manual Rev 02 January 2004 Page 2 Chapter 03 INSTALLATION Before connecting the JLab 300 Plus remove the protective packing material placed under the sampling arm and under the wash station group Warning in the event that it is necessary to repack any or all of the delivered item s the following procedures must be carefully followed gt Reposition the protective packing mate
146. g the fastening screws Fig 10 Sampling Interface assy PN 23300019201 Fig 10 ILab 300 Plus Service Manual Rev 04 January 2004 Page 17 Chapter 06 SETTINGS AND ADJUSTMENTS N B In order to be able to remove the M6 motor from its support it is necessary to first partially disassemble the module as shown in Fig 12 9 Unscrew the three fastening screws Fig 11 and remove the base as shown in Fig 12 10 Remove the motor fastening screws and loosen its pulley screws Fig 13 11 Take out the M6 motor and substitute it with the new one 12 Lift the pulley to approximately 0 5mm from its upper limit and tighten its screws Fig 13 13 Push the motor outward as shown in Fig 9 and holding it in this position so as to maintain the belt in tension tighten the motor fastening screws 14 Tighten the base support screws Fig 11 15 remount repeat the above steps in inverse order from 8 to 1 Warning Do not tighten the protective cover s set screw as this could result in mechanical malfunction of the sampling arm s vertical movement Fig 4 Warning After having substituted the motor it is necessary to mechanically align the probe with respect to the wash well and center all the other positions by following the procedures provided in Section 6 1 1 Alignment and Adjustments M5 Motor Assy Vertical PN 23100039900 ILab 300 Plus Service Manual Rev 04 January 200
147. gnals and additional digital processing circuitry serving as A D converter and providing an ASCII signal output to the chemistry analyser Each of the electrodes can be easily removed from the front of the housing ILab 300 Plus Service Manual Rev 02 January 2004 Page 6 Chapter 12 Ise Module 12 6 ELECTRODES The electrodes are maintenance free and are warranted on a prorated basis for up to 10 000 samples or 6 months whichever occurs first Cleaning Solution aspirated from an operator designed sample cup is used at least once a day at the end of the day in order to minimize protein build up in the fluid lines A two point calibration of the ISE module is also done at least once a day at the beginning of the first sample run If the user is running more than 50 samples a day both cleaning and calibrant must be performed after 8 hours by the host analyzer The entire double junction reference electrode is disposable The reference electrode is filled with sufficient KCL so that no filling solution must be added during the lifetime of the electrode Electrodes require calibrant sampling at 30 minutes intervals for reliable operation but this is completely controlled by the Electrolyte Measurement System without any need for control by the host analyzer or the operator The electrodes require a 10 times sample dilution for measurement of urine The ISE module depends on the host analyzer to perform the dilution function It is not ne
148. guide lock 6 3 2 4 Function check for the peristaltic pump 1 Turn on 300 Plus system and launch the Analyzer program Select Start Work and perform one or more cuvette washing cycles Make sure that the sampling probe washing well empties completely without any leakage of liquid If leakage should occur adjust the screw indicated in Fig 5 using the Peristaltic Pump Setting Gage as illustrated in figure 6 See Service News 9 dated 21 05 2003 2 Close the 300 Plus program by clicking on Shutdown 6 3 3 SUBSTITUTION OF PART S gt N B Make sure the instrument ILab 300 Plus is turned off before performing this substitution procedure 1 Unscrew the two knobs to remove the door located on the front elevation of the instrument Fig 1 and the two noticeable screws located on the rear panel Fig 2 to access the washing pump assembly 2 For each part to be replaced if necessary disconnect the relative electrical power connection the hydraulic tubes and the fastening screws 95 If necessary unscrew the four anchored screws of the assembly and turn it ahead Fig 2 4 Remount repeating the above steps 3 through 1 in reverse order ILab 300 Plus Service Manual Rev 04 January 2004 Page 41 Chapter 06 SETTINGS AND ADJUSTMENTS Any necessary adjustments in order to optimize pump aspiration in relation to the newly substituted tube can be made by turning the relative screw Fig
149. he washing station Remove the top cover and check that the cuvettes are well fitted in their slot Connect the ILab 300 Plus to the P C see 3 4 LI ILab 300 Plus Service Manual Rev 02 January 2004 Page 7 Chapter 03 INSTALLATION Activity Install the 300 Plus program provided with the CD Rom Perform all the P C settings see Installation Procedure point 1 to 11 sect 3 6 1 Keep the arm completely up and turn the instrument the and the Printer on After removing the protection tube install the probe Verify that the probe is perfectly straight see Installation Procedure point 12 to 14 sect 3 6 1 Reconstitute the Rinse and cleaning solutions by following the instructions sheet in the packing gt Place the three bottles in position and fill them with the relevant liquid H20 Rinse Cleaning Close with the covers and insert the tubes Place the two waste tank one is the biological waste Not supplied Insert the waste tubings The connector is the biological outlet Check the tubings for any squashing Boot ILab 300 Plus program and run the Diagnostic select Diluter and click on the Probe Wash Test command to execute the priming Perform the Washing Well Level see Installation Procedure point 15 to 16 sect 3 6 1 Open the Glo
150. hen lowers into the wash well so that it can be washed externally to minimize cross contamination 5 The arm moves to the specified sample and aspirates a third air bubble 6 When the level sensor senses the liquid the arm stops and aspirates the sample 7 The arm rises once again while the diluter aspirates a fourth air bubble to prevent sample loss 8 At this point the arm returns to the wash well in order to clean the outside of the probe and it aspirates a fifth air bubble 9 The arm moves to the reaction plate and dispenses reagent and sample in the reaction cuvette for incubation and reading 10 The arm returns to the wash well and carries out a probe wash cycle ILab 300 Plus Service Manual March 2003 Rev 01 Page 5 Chapter 2 GENERAL DESCRIPTION 23 SAMPLING SYSTEM Reagent Aspiration Air Aspiration To separate the reagent from serum To the washing well for probe cleaning Air Aspiration To the washing well for probe cleaning Dispensing in cuvette To the washing well for final cleaning ILab 300 Plus Service Manual March 2003 Rev 01 Page 6 Chapter 2 GENERAL DESCRIPTION 2 4 WASHING STATION The reaction plate washing station is made up of a series of five probes situated to one side of the reaction plate The probes are connected to the valve and pump system for emptying washing and drying operations please see the hydraulic diagram 241 WASHING STATION
151. hlorite solution 8 Once the Tip is clean repeat the aspirating and dispensing cycle 10 more times using distilled water then disconnect the syringe ILab 300 Plus Service Manual Rev 03 January 2004 Page 8 Chapter 07 Mantenance 9 Re connect the aspiration tube to the cannula 10 Re position the cannula in its housing being careful to not kink the aspiration tube 11 Re position the spring on the cannula s cylindrical axel ILab 300 Plus Service Manual Rev 03 January 2004 Page 9 Chapter 07 Mantenance 12 Close the lid making sure that the cylindrical tops of the cannulas fit into the corresponding holes on the lid Locking Screw 13 Insert the blocking screw into its setting and screw it down using the special tool included among the instrument s accessories IMPORTANT Before starting the instrument back up manually move the wash station upwards as far as it will go ILab 300 Plus Service Manual Rev 03 January 2004 Page 10 Chapter 07 Mantenance 7 6 2 PROCEDURE FOR REPLACING THE POROUS PAD 1 Turn off the Analyzer 2 Unscrew the screw that fastens the black top cover of the wash station using the special tool included among the instrument s accessories 3 Remove the wash station cover lid and take out the cannula containing the Tip Be very careful to not lose the spring 4 Disconnect the aspiration tube remove the used Tip and replace it with a new one Press ligh
152. ig 2 9 Unscrew the two fastening screws from the bottom cover panel of the washing station and lift it Fig 4 10 Unscrew the two fastening screws on the cuvette holder assembly and lift it This will make it possible to remove the analysis plate Fig 5 11 Unscrew the two fastening screws on the optic sensor and substitute it with the new one 12 Remount repeating the above steps 11 through 1 in reverse order Fastening screws on the bottom cover panel of the washing station Fig 4 Washing Station probes assembly PN 23910000600 Cuvette Holder Solenoid PN 23910006000 Fastening screw on the cuvette holder assembly Fig 5 Cuvette Holder N B After substituting the optic sensor carry out the mechanical adjustment procedure of the reaction plate as described in Section 6 4 1 ILab 300 Plus Service Manual Rev 04 January 2004 Page 47 Chapter 06 SETTINGS AND ADJUSTMENTS 6 4 4 SUBSTITUTION OF THE M3 MOTOR gt N B Make sure the instrument ILab 300 Plus is turned off before performing this substitution procedure Remove the reaction plate cover Fig 1 Unscrew the four cross bas fastening screws and remove the cross bar Fig 1 Unscrew the four anchored screws of the reaction plate module Fig 3 P oue B Remove the J1 and J4 connectors and the ground wire from the Reaction Chamber Motor Interface Fig 3 Remove J1 J14 connectors and the ground wire fro
153. ined against the laboratory s quality control values Lamp Holder Alignment Reference Point Fig 3 Fig 4 WARNING DO NOT TOUCH THE GLASS PART OF THE LAMP WITH YOUR FINGERS IF NECESSARY USE A CLEAN CLOTH TO REMOVE DUST OR ALCOHOL TO REMOVE MORE STUBBORN DIRT ILab 300 Plus Service Manual Rev 03 January 2004 Page 15 Chapter 07 Mantenance 7 10 CHANGING THE REACTION CUVETTES Over time and through normal use the perfect transparency of the cuvettes diminishes This less than perfect transparency has a negative impact on the quality of the optical readings The manufacturer suggests that the cuvettes be replaced after two months of use The cuvettes are located inside the reaction plate 7 10 1 PROCEDURE FOR REPLACING THE REACTION CUVETTES 1 Turn the Analyzer and wait until the instrument has reached its proper operating temperature Select Checks gt WBL and click on the cell that must be replaced Click on Change located under the work program Please see Chapter 03 Operator Manual Description of Instrument Software A pull down menu will appear Click on Plate First Half and then on OK A dialog box will appear asking Do you want to change the cuvettes requested Click on OK to confirm Remove the reaction plate coverlid Remove the cuvettes numbered 1 through 30 by VERTICALLY lifting them out from their housing and then replace them with new cuvettes Make sure to reinsert the new
154. ing is property of AMS any use without Analyzer y coran authorization will be prosecuted accordingly to the law Medical Tiburtina eim 18 00012 Guidonia Roma Description Scale Sheet Rev Approved Date SCHEMATIC POWER SUPPLY 08 01 2002 Peristaltic pump wa Top view Eg 1 Channel 2 Channel 1 post CHASSIS ASSY 15 00435 00 89 NE WASHING STATION PROBES r 9 10 0006 00 Dist water Emission Kit fitting 9 65 0033 03 Blue Kit fitting 9 65 0033 02 Yellow Kit fitting 9 65 0033 00 Red Y fitting 9 35 0053 00 Manifold assy 05 00405 00 Fitting 9 35 0051 00 PVC tubing 613 0 5 PVC tubing i3 9e5 PVC tubing i3 9e5 PVC tubing 9 i4 9e6 PVC tubing i3 9e5 PVC tubing i3 9e5 PVC tubing i3 9e5 Silicon tubing 4i4 9e6 Silicon tubing 14 SN sem p 7 alt y o 7 4 3 Silicon tubing 4i2 9e4 Silicon tubing 4i2 9e4 Silicon tubing 4i2 9e4 Peristaltic pump tubing Silicon tubing 4i2 9e4 Silicon tubing 4i2 9e4 7 Silicon tubing i1 6 9e3 2 Silicon tubing i1 6 9e3 2 Silicon tubing i1 6 9e3 2 Silicon tubing i1 6 9e3 2 Silicon tubing 9i1 6 9e3 2 Teflon tubing AWG16 VW1 DESCRIPTION 4 gt o EF ty L 3 mi 30 29 28 26 25 2
155. ington interface for 16 signals whose output can be sent to various devices including electro valves continuous current motors CIRCUIT DESCRIPTION The following description refers to the SE 00188 01 Rev B electrical wiring diagram POWER SUPPLY The main power supply VM 24 V applied via J3 and indicated by the lit green D22 LED is used for the stepper driver power portion TA8435H The secondary power supply 12 5 Volts also comes through connector J3 is filtered by condenser C13 monitored via the green D21 LED and used to generate the 5 Volts necessary for the stepper driver logic section and for the pull up resistors The 5 volts are obtained from the 12 5 Volts through 05 LM7805 and the 4 filter condenser ILab 300 Plus Service Manual March 2003 Rev 01 Page 18 Chapter 2 GENERAL DESCRIPTION STEPPER MOTORS DRIVER The four drivers are represented by the U1 U2 U3 and U4 components Following is a description of the functioning of the first U1 of the four identical circuits Later on in this manual a brief description of the functioning of the NMB SDI C403 device or TOSHIBA s equivalent TA8435H will be provided The driver under examination is made up of A logic section for decoding signals arriving from the control board via the JA and J7 connectors which uses the following inputs DIRA pin 5 determines the direction of the rotation of the motor RES pin 2 reset CLKA 6 con
156. ip is used to dry the cuvettes after they have been washed This drying process is carried out via aspiration and therefore over time the Tip will necessarily absorb various contaminating particles The manufacturer suggests that the Tip be replaced every six months Said frequency may vary depending on the workload of the individual laboratory the operating conditions environment of the single instrument The Tip must be washed regularly in order to guarantee proper functioning and must be replaced with a new Tip as necessary 7 6 4 POROUS PAD CLEANING PROCEDURE 1 Turn off the Analyzer 2 Remove the top cover lid of the Wash Station using the specific tool included among the instrument s accessories Special tool Blocking screw 3 Remove the cannula that contains the Tip the 5 cannula and disconnect the aspiration tube 4 Remove the spring Aspiration tube ILab 300 Plus Service Manual Rev 03 January 2004 Page 7 Chapter 07 Mantenance 5 Once the cannula has been removed immerge it in a 5 solution of sodium hypochlorite for at least 15 minutes 6 Attach a 10 ml syringe to the cannula as illustrated in Figure 6 7 Aspirate and dispense the hypochlorite solution through the cannula and the Tip until the latter is completely clean This aspirating and dispensing forces the liquid through the Tip fibers in both directions Please see Figure 7 Connect the syringe to the cannula Sodium hypoc
157. ith the standard UNI EN591 which requires a manual to be supplied with vitro diagnostic instruments for professional use 12 SYSTEM INTRODUCTION The ILab 300 Plus system is a continuous load random access bench top instrument for performing chemical and immuno turbo dymetric clinical analysis It is totally automatic and computer controlled 1 3 PRECAUTIONARY MEASURES 1 3 1 Chemical risks The individual operator is responsible for assuring that all possible precautionary measures are taken against eventual risks associated with the use of the ILab 300 Plus instrument in clinical laboratory settings The manufacturer will provide the reagents kit and specific written information on the use of each of the reagents It is important that the samples be well coagulated and then carefully centrifuged Samples which contain fibrinogen clots can obstruct the probe and lead to inexact sampling If blood samples containing gel are used it is suggested that the manufacturer s recommendations be followed Immediately clean and remove any accidental leakage of reagent or other liquid 1 3 2 Electrical risks As with any electrical device the risk of electric shock exist Is therefore necessary to take every precautionary measure possible when working with this or any other electrical instrument to avoid contact with power supply wires electrical components or electronic boards ILab 300 Plus Service Manual Rev 02 Januar
158. lectronic components are turned on The Stand by light placed on the front panel will flash until the reaction plate reaches a temperature of 36 C At this point the Stand by light will stop flashing and will remain constantly lit In the case of system failure or malfunction the Ready light situated on the front panel of the instrument will light up red In order to enter the main program double click on the JLab 300 Plus icon on the computer desktop The main menu System Monitor will appear Whenever any system function is launched the color meter lamp and the sampling arm pre heater will receive regular power ILab 300 Plus Service Manual March 2003 Rev 01 Page 3 Chapter 2 GENERAL DESCRIPTION 2 1 ANALYTICAL CYCLE 211 REACTION PLATE The reaction plate of the JLab 300 Plus system contains 60 washable and reusable plastic cuvettes The cuvettes can be removed individually Cuvette washing takes place under the reaction plate washing station There are five positions which alternate in the washing and drying of the cuvettes The basic operating cycle of the reaction plate takes 18 seconds Said cycle includes optic reading of the cuvettes in incubation aspiration and dispensation of the reagents and samples by the arm repositioning of the plate and washing of the cuvettes The reactions take place at 37 C this temperature is constantly maintained by the heater placed under the reaction plate 2
159. m press Shutdown key Fig 1 Refrigerated Reagent Rack assembly ILab 300 Plus Service Manual Rev 04 January 2004 Page 68 Chapter 06 SETTINGS AND ADJUSTMENTS 6 7 RACKS HOLDER ALIGNMENT 6 7 1 MECHANICAL ALIGNMENT OF THE SAMPLES RACKS HOLDER Warning A check of the mechanical alignment of the samples racks must be performed every time a rack is removed either for servicing or substitution N B Make sure the instrument ILab 300 Plus is turned off before performing this procedure 1 Open the two front panels and remove the samples and STAT racks 2 Remove the top cover of the samples Fig 1 3 Loosen the four fastening screws on the samples racks holder Fig 2 4 Replace the top cover of the samples Place empty samples cups in the first and last positions of the racks and reinsert the racks ail Align the holes of the caps with those of the top cover of the samples 6 Once again remove the top cover of the samples remove the racks and tighten the fastening screws of the samples racks holder 7 Reposition the racks and replace the top cover of the samples 8 Close the two front panels Fig 2 Samples racks holder top cover of the samples ILab 300 Plus Service Manual Rev 04 January 2004 Page 69 Chapter 06 SETTINGS AND ADJUSTMENTS 6 7 2 MECHANICAL ALIGNMENT OF THE REAGENTS RACKS HOLDER Warning A check of the mechanical alignment of the reagents racks must be performed
160. m the Reaction Plate Interface Fig 3 6 Open the cover panel of the peristaltic pump assembly and disconnect the seven tubes attached to the probes on the washing station 7 Remove the reaction plate from the instrument 8 Unscrew the four fastening screws that hold the motor support Fig 7 9 Remove the four fastening screws on the motor Fig 8 10 Remove the motor and substitute it with the new one 11 Remount repeating the above steps 9 through 1 in reverse order Warning Belt tension must be regulated by turning the M4 screw shown in Fig 7 clockwise by 1 3 Kg cm Belt tension screw Fig 7 ILab 300 Plus Service Manual Rev 04 January 2004 Page 48 Chapter 06 SETTINGS AND ADJUSTMENTS Belt for reaction plate PN 23935003200 Motor fastening screw M3 Stepper Motor assembly motor with pulley PN 23910001601 N B After substituting the motor carry out the mechanical adjustment procedure of the reaction plate as described in Section 6 4 1 ILab 300 Plus Service Manual Rev 04 January 2004 Page 49 Chapter 06 SETTINGS AND ADJUSTMENTS 65 WASHING STATION ASSEMBLY 6 5 1 SUBSTITUTION OF THE WASHING STATION ASSEMBLY N B Make sure the instrument ILab 300 Plus is turned off before performing this substitution procedure Remove the reaction plate cover Fig 1 Unscrew the four cross bas fastening screws and remove the cross bar Fig 1 Un
161. manual movement of the plate 5 6 5 REACTION PLATE AREA 1 command Reset Performs the resetting of the reaction plate bringing the n 1 cuvette in the distribution position reaction disp 5 6 6 STATUS COMMAND AREA Send Visualizes the commands sent by the program to the instrument hardware Receive Visualizes the instrument hardware s response to the commands sent by the program ILab 300 Plus Service Manual Rev 02 January 2004 Page 18 Chapter 05 DIAGNOSTIC PROGRAM 5 7 TEMPERATURES FOLDER DIAGNOSTIC Temp TestRun Calib Sensor z 0 Wash Staton Esos fee a Wash Station Rise Diwater StBy The Temperature Folder is subdivided into three areas Temperatures Offset Status Command 5 7 1 TEMPERATURES AREA 4 commands Temp Test Run To enter in the Temperature Test folder Plate Performs a temperature reading in the reaction plate compartment Arm Performs a temperature reading in the arm s pre heater Calib Sensor To carry out the calibration procedure of the thermometric probe included in the kit P N 23550120400 as illustrated in Chapter Six Settings and Adjustments ILab 300 Plus Service Manual Rev 02 January 2004 Chapter 05 DIAGNOSTIC PROGRAM 5 7 2 OFFSET AREA 2 commands To correlate the thermometric probe included in the kit P N 23550120400 with another refe
162. n ILab 300 Plus Service Manual March 2003 Rev 01 13 72 04 15 77 18 16 J10 19 Page 27 Chapter 2 GENERAL DESCRIPTION 2 5 6 REACTION CHAMBER MOTOR INTERFACE This board distributes the motors signals those of the filters wheel J2 washing station 73 and reaction plate J4 part of the Reaction Group Assy The connector J1 interfaces the Stepper Motors Driver Board 30 00188 01 which is managed by the Micro P of the CPU via connector J1 Signal distribution for the three motors is carried out via the three above cited connectors ILab 300 Plus Service Manual March 2003 Rev 01 Page 28 Chapter 2 GENERAL DESCRIPTION 2 57 PRE AMPL ADC The FD1 photodiode detects light energy arriving from the optics The amplifier U2 amplifies this signal and sends it to the A D serial converter ADS 1250 Both U1 and U4 produce the 5 the former for the analogic segment and the latter for the digital segment US generates 5V and U6 the voltage reference VREF Y1 is the oscillator connected to the U3 clock The and signals determine the U3 gain 1 2 4 or 8 The Board interfaces with the Reaction Tray Interface Board 00193 01 via the 1 1 connector that sends the signals to the Micro P ILab 300 Plus Service Manual March 2003 Rev 01 Page 29 Chapter 2 GENERAL DESCRIPTION 2 5 8 PHOTOMETER
163. nalyzer System OIIIARIO2II GLU HH E EEEEEEEEO LEEEEEEEE EF HE B 1 8 6 RESULTS RECORD R Field Field Title Down Up Max Load Load Len Record Type ID A This is a required field that contains an R identifying it as a Results Record 2 Sequence Number This field starts with 1 for the first result and is incremented by 1 for each additional result within the record This will be reset to 1 when the results from another test order record are transmitted to the laboratory computer ILab 300 Plus Service Manual Rev 03 January 2004 Page 10 Chapter 08 Host Communication Universal Test ID This is a four component field N e Universal Test ID Code not N used e Universal Test ID Name N 9 used Universal Test ID Type not A used e Local Manufacturer s or local code 6 characters this is the code defined in the Analyzer Data or A 10 Data is 10 character floating point Measurement value field that includes the decimal point The number of precision point digits will vary according to the test and is configurable on the Analyzer Units of Measure A 6 This is a field for up to 6 characters that the operator defines for analytic measurement Reference Ranges A 21 This field has two components one giving the lower limit and the other the upper limit of the range The format for this field is NAN
164. nical inversion of the motor s rotation it is necessary to mechanically recuperate the Diluter in uL the value to be inserted can be calculated using the following procedure 1 Enter in the Diagnostic program and make the Sampling Arm Reset into the Arm folder 2 Enter in the Diluter folder press the HOME button 3 Push PROBE WASH TEST button three times in order to fill the hydraulic sampling line completely 4 Remove the samples protective cover and the sample racks from their housing 5 Enter in the ARM folder and push the GO button in order to move the probe in the sampling position number 1 6 Put a sample cup containing distilled water under the probe about 1m1 7 Enter in the DILUTER folder and aspirate 300 uL of distilled water 8 Remove the sample cup containing distilled water and put a plastic sheet under the probe 9 Select 30 uL of distilled water and dispense it on the plastic sheet 10 Select 1 uL of distilled water and aspirate a certain number of times until seeing an aspiration like effect in the drop on the probe 11 The number of aspirations performed until one sees the aspiration effect represents the BACK LASH value to be inserted into the specific field in the Configuration folder 12 Push the Save button to memorize the inserted data 13 Push the Reset button into the ARM folder 14 Close the Diagnostic program by clicking on the Diagnostic button Heater to adjust the setting of the sample
165. nnected to J8 and sent to the Micro P The cuvette holder solenoid is turned on by activating the BCU signal produced by a Darlington controlled by the Micro P The PWMP signal that controls the reaction plate heater is also produced by the Micro P Its power absorption is controlled via the P71 signal Furthermore the board distributes toward other modules input and or output signals managed by the CPU 24V and 12 5V arrive to the board The 5V U5 used for the amplifiers and the negative voltage U4 that is sent to both the Sample and Reference PRE AMPL ADC are produced here ILab 300 Plus Service Manual March 2003 Rev 01 Page 26 Chapter 2 GENERAL DESCRIPTION 2 5 5 1 REACTION TRAY INTERFACE INPUT OUTPUT Home Washing Station Home Filters Wheel Home Reaction Tray Home Cuvette Holder Reaction Tray Leak Reaction Tray Temperature Sensor PWMP PWM for the Heater BCU Activation of the Cuvette Holder Solenoid OFFPL Activation of the Lamp Feedthrough Cuvette Solenoid Holder Reaction Tray Heater ALFD3 three light emitting diodes in series OS3 Washing Station Home Sensor OS2 Filters Wheel Home Sensor OS4 RTC Tray Home Sensor OSB Cuvette Holder Home Sensor ALFD1 Cuvette Holder Sensor Diode Control P72 Reaction Plate Temperature LEAKP Reaction Plate Leak P71 Reaction Tray Heater Power Control V Voltage 12V for PRE AMPL ADC PWRES Heater Power OFFPL Lamp Activatio
166. nse to the commands sent by the program ILab 300 Plus Service Manual Rev 02 January 2004 Page 13 Chapter 05 DIAGNOSTIC PROGRAM 5 5 OPTIC FOLDER DIAGNOSTIC Campas Wash Station Filter Wheel Cuv Holder Clean The Optic folder is subdivided into five areas OPERATIONS SENSOR STATUS FILTERS DIGITAL CONVERSION STATUS COMMAND ILab 300 Plus Service Manual Rev 02 January 2004 Page 14 5 5 1 OPERATIONS AREA 2 commands Lamp ON Turns on the Optic Lamp Lamp OFF Turns off the Optic Lamp 5 5 2 SENSOR STATE AREA This area indicates the status of the wheel filters 5 5 3 FILTERS AREA 10 commands Chapter 05 DIAGNOSTIC PROGRAM Reset Positions the wheel filters in home position dark 340 nm Positions filter n 1 in front of the reading sensor 380 nm Positions filter n 2 in front of the reading sensor 405 nm Positions filter n 3 in front of the reading sensor 492 nm Positions filter n 4 in front of the reading sensor 510 nm Positions filter n 5 in front of the reading sensor 546 nm Positions filter n 6 in front of the reading sensor 577 nm Positions filter n 7 in front of the reading sensor 620 nm Positions filter n 8 in front of the reading sensor Spare Positions filter n 9 in front of the reading sensor Optional ILab 300 Plus Service Manual Rev 02 January 2004 Page 15 Chapter 05 DIAGNOSTIC PROGRAM 5 5
167. o four areas TABLE POSITION KEYBOARD DOWNARM SETTING OF ILab 300 Plus Service Manual Rev 02 January 2004 Page 28 Chapter 05 DIAGNOSTIC PROGRAM 5 11 1 TABLE POSITION This table has five columns Position Rot A amp B Rot B Offset A amp B Offset B Lists all the possible instrument positions samples reagents standard controls diluents ISE dispense Gives the base steps for the complete arm internal and external in every position Gives the base steps only for the external arm in every position Gives the corrective steps necessary for the arm s adjustment internal and external Gives the corrective steps necessary for the external arm s adjustment Next to the Sample Table there are 3 commands Prev Next Go 5 11 2 KEYBOARD The various positions Returns the arm to the previous position Brings the arm to the successive position Brings the arm to the first position according to the category selected in the area Setting of Sample reagent Std Ctrl Dil Ise Disp can be improved through the keyboard saving the operations performed The areas visible in Fig 6 may be activated by the mouse or with the help of the numerical buttons on the keyboard The buttons are listed with their corresponding function The Keyboard Num Lock S h must be set to ON Previous aves the CW Rotation Free Position settings Mum
168. of Sample 8 672 108 z 11 6 Sample Sample 9 792 44 7 17 C Reagent Sample 10 988 4 10 18 J Sample 11 41844 4 C Std Ctrl Sample 12 1400 40 11 6 C Dil Ise Disp Sample 13 1588 104 15 10 OCemnlan 14 1740 109 _ Micro 1 Reaction Wash Station Home Sensor Rack Door Diagnostic 23 11 2001 Diagnostic ILab 300 Plus Service Manual Rev 02 January 2004 Page 30 Chapter 05 DIAGNOSTIC PROGRAM arm centering can be adjusted at the highlighted area by giving commands through the keyboard or mouse 8 CW Rotation 2 CCW Rotation 4 Open External Arm 6 Close External Arm Next Position Previous Position Repeat the centering for all the relevant positions Push the Save button to save the operations performed Wait for the arm to automatically reset NOTE If the option Manual default is chosen in the Down Arm area to make the arm go up and down it is possible to use either the buttons pgUp and pgDn or click with the mouse on the button with the arm figure in the Down Arm Area WARNING THE FIRST TIME THAT THE SETTING PROCEDURE IS PERFORMED IT IS EXTREMELY IMPORTANT TO CHOOSE THE MANUAL OPTION IN THE DOWN ARM AREA BY CHOOSING THE AUTOMATIC OPTION THERE IS A CONSIDERABLE RISK OF BREAKING THE PROBE DUE TO POSITIONS THAT HAVE NOT BEEN PROPERLY CENTERED ILab 300 Plus Service Manual Rev 02 January 2004 P
169. of the cuvette Tighten the cuvette holder trigger fastening screw Fig 8 5 Turn on the ILab 300 Plus system and launch the Analyzer program 6 Launch the diagnostic program and select the Plate function 7 Reset by clicking on the appropriate key Make sure the Home Sensor Reaction Plate window lights up green 8 Select the Wash function and reset by clicking on the appropriate key 9 Make sure the Home Sensor Washing Station window lights up green 10 Select Home and Down several times by clicking on the appropriate keys Make sure the Home Sensor Cuv Holder window lights up green when the washing station is in the Home position and lights up red when the washing station is in the Down position If not loosen the fastening screw on the opto sensor flag and adjust to obtain the correct signal Fig 7 11 To exit the diagnostic program press the Diagnostic key 12 To exit the analyzer program press Shutdown key ILab 300 Plus Service Manual Rev 04 January 2004 Page 56 Chapter 06 SETTINGS AND ADJUSTMENTS Cuvette holder trigger fastening screw i FN Fastening screw on the opto sensor flag Opto coupler assy PN 23910002300 Cuvette Holder Solenoid PN 23910006000 Fig 7 Cuvette Holder Top edge of the cuvette holder trigger Top edge of the cuvette Fig 8 Reaction cuvettes ILab 300 Plus Service Manual Rev 04 January 2004 Page 57 Chapter 06
170. om its reciprocal system The instrument does not send or accept comment records 8 3 HEADER RECORD Field Field Title Down Max Description and Valid Values Load Load 1 Record Type ID 1 This is a required field that contains an H identifying it as a header record 2 Delimiters I 4 The Analyzer System uses only the four default values shown here Delimiters may not be duplicated The field delimiter follows the escape character to separate the delimiter specification from a subsequent field in the header record Using default values the first six characters of the header record will appear using the following characters I amp I Field Delimiter I Repeat Delimiter Component Delimiter Escape Delimiter amp 3 Message Control I N ID 4 Access Password I N Sender Name or I A 10 SHAnalyzer This is the name of the ID device that is sending the data 6 Sender Street I N Address 7 Reserved Field I N Sender Tel I N Number 9 Characteristics of I N Sender ILab 300 Plus Service Manual Rev 03 January 2004 Page 4 Chapter 08 Host Communication 10 Receiver ID I N 11 Comments or I N Special Instructions 12 Processing I N 13 ASTM Version I N 14 Date and Time I A 14 Date and Time of transmission formatted as YYYYMMDDHHMMSS For example 3 35 PM on March 1 1995 would be re
171. on plate Select the Optic function and turn the lamp On by clicking on the appropriate field Reset the filter wheel by clicking on the appropriate key Make sure that Home Sensor Filter Wheel window lights up green A ek OBL SE EP Make sure that the Regulator board for Connector M1 shows 6 0 volts 0 1 If not turn the P1 trimmer Fig 4 N B The reaction cuvette must be perfectly clean If not carry out a Cuvette Wash cycle Start Work Warning Room lighting and daylight can influence the reading To avoid this interference replace the reaction plate cover panel before carrying out any check procedures 9 Click on Start Sample Channel Conversion key and make sure that the adjacent window shows a count value from 50 to 100 If not adjust the Preamp ADC board Offset trimmer inside the analysis plate in order to set the desired value Fig 5 10 After regulating of the main channel offset it is necessary to click on Stop Sample Channel Conversion key 11 Click on Start Reference Channel Conversion and make sure that the adjacent window shows a count value from 50 to 100 If not adjust the Preamp ADC board Offset trimmer of the reference channel located external to the analysis plate in order to set the desired value Fig 5 12 After regulating of the reference channel offset it is necessary to click on Stop Reference Channel Conversion key ILab 300 Plus Se
172. orders and demographics only ILab 300 Plus Service Manual Rev 03 January 2004 Page 13 Chapter 08 Host Communication Example Request Information Record Layouts Q Download To Analyzer System 1 amp III SHAnalyzer 11111111 20020927100402 QIIIALLITIITITITILO LILIN ILab 300 Plus Service Manual Rev 03 January 2004 Page 14 Chapter 09 Error Signaling And Troubleshooting CHAPTER 09 ERROR SIGNALING AND TROUBLESHOOTING INDEX 9 1 ERROR SIGNAL ING ceoe cates jas oni co eo 2 9 1 1 SYSTEM ERRORS aieo in ien qoe repaid idee ea roe ala les 2 RESUL TE ES C aM 3 9 1 3 DESCRIPTION OF RESULT FELAGS 4 9 23 TROUBLESHOOTING GUVJIDE 52 2 2 eto i ret ether Sieb einer sie 8 ILab 300 Plus Service Manual Rev 02 January 2004 Page 1 Chapter 09 Error Signaling And Troubleshooting 91 ERROR SIGNALING This chapter is dedicated to a description of the error signaling which may occur during the programming or carrying out of the various operations Error signals can be divided into the following two groups System Errors Result Flags 9 1 1 SYSTEM ERRORS Whenever a system error is detected it is signaled via the activation of the below listed warning lights buttons Warning Light a triangle shape located in the upper right hand portion of the System Monitor screen It lights up yellow when activated
173. osition Prev Brings the arm to the previous sample standard dilution or reagent position Reset Completely resets the arm In this area the boxes can be activated when the arm is positioned on a sample a reagent a standard or a control Original step Visualizes the number of base steps Offset Visualizes the number of offset steps ILab 300 Plus Service Manual Rev 02 January 2004 Page 11 Chapter 05 DIAGNOSTIC PROGRAM 5 4 DILUTER FOLDER DIAGNOSTIC The Diluter Folder is subdivided into four areas OPERATIONS SENSOR STATE USER STATUS COMMAND ILab 300 Plus Service Manual Rev 02 January 2004 Page 12 Chapter 05 DIAGNOSTIC PROGRAM 5 4 1 OPERATIONS AREA 3 commands Home Brings the diluter to the Home position Asp Aspirates the micro litres as predetermined in the ul box may be set manually through and or by using the cursor located immediately above Disp Distributes the micro litres as predetermined in the ul may be set manually through and or by using the cursor located immediately above 5 4 2 SENSOR STATE AREA In the Sensor State area the diluter sensor status is indicated 5 4 3 USER AREA 1 command Probe Wash Test Activates and deactivates the probe wash system 5 4 4 STATUS COMMAND AREA Send Visualizes the commands sent by the program to the instrument hardware Receive Visualizes the instrument hardware s respo
174. other Micro tin soldered jumper on pins 2 1 of J11 In this case the arbitration between the two Tx signals is carried out in the BOOT phase via the SELP signal and in the operative phase via the R10 and signals which the two Micros exchange and which respectively receive on signals P14 and R14 everything governed by programmable logic Service Manual March 2003 Rev 01 Page 15 Chapter 2 GENERAL DESCRIPTION The two Micros carry out program downloading via J2 in addition to the TX and RX signals also the following signals are utilized for this function SELP which goes directly on the programmable logic and which if low signals that it wants to load the program on Micro R RTS and DTR which after the RS232 TTL conversion become BOOT RESB and are brought back on the programmable logic for reset generation and for enabling the programming voltage for Micros P R The same program is loaded on the two Micros In the operative phase the format of the communication messages with the PC contains an address number for those messages which can be processed only by Micro P recognized because the PB6 input is high 2 for those messages which can be elaborated only by Micro R recognized because the RB6 input is low The four TTL RS232 conversions 90 transmission toward Micro P s auxiliary device 90 transmission toward Micro R s auxiliary device
175. otor Interface board Fig 2 Remove the J1 J2 J14 connectors and the ground wire from the Reaction Plate Interface board Fig 2 Open the peristaltic pump assembly panel cover Unscrew the two fastening screws to make free the support that join the seven tubes coming from the washing station probes Disconnect the six tubes coming from the washing station probes and the air tube inserted on the micro pump P4 coming from the porous pad on fifth probe of the washing station Remove the reaction plate from the instrument Remove the lamp s power supply wires connected to the Lamp Regulator board by loosening the two screws on the M1 connector Fig 4 Remove the J1 connectors from the Preamp ADC Fig 5 and the ground wire from the optic group Unscrew the four fastening screws remove the optic assembly and substitute it with the new one Fig 3 Remount the assembly repeating the above steps 11 through 1 in reverse order After remounting reseat the lamp and carry out the electronic adjustment check procedures as described in Sections 6 2 2 and 6 2 3 ILab 300 Plus Service Manual Rev 04 January 2004 Page 31 Chapter 06 SETTINGS AND ADJUSTMENTS Reaction Plate cover panel Fig 1 Reaction Tray Interface PN 23300019301 Anchored screw Motor fastening screw Fig 3 New photometer assy 2optic Channel PN 23100010800 ILab 300 Plus Service Manual Rev 04 January 2004 Page 32 Chapter 06 SETTINGS AND ADJUSTMENT
176. out a Wash cuvettes cycle and then a WBL cycle Make sure that there is no leakage Check system efficiency by comparing the WBL values and the test results obtained against the laboratory s quality control values ILab 300 Plus Service Manual Rev 03 January 2004 Page 17 Chapter 07 Mantenance 7 12 TABLE C LIST OF THOSE MAINTENANCE PROCEDURES THAT CAN BE PERFORMED BY THE USER AND OR BY THE MAINTENANCE TECHNICIAN PROCEDURE FREQUENCY EFFECTUATED BY CLEANING THE SAMPLING PROBE DAILY OPERATOR CLEANING THE FOUR WASH STATION EVERY TWO CANNULAS WEEKS OPE RAEO CLEANING THE WASH SOLUTION EVERY TWO BOTTLES WEEKS OPERA EOR EVERY TWO REPLACING REACTION CUVETTES MONTHS OPERATOR CLEANING THE POROUS PAD ONCE A MONTH OPERATOR REPLACING THE PROUS PAD AS NEEDED OPERATOR ALIGNING AND ADJUSTMENT OF THE QM SAMPLING ARM SERWICEENG Std amp Ctr Reagents Samples Dispensing y part REPLACING THE PERISTALTIC PUMP EVERY SIX TUBES MONTHS DEBRIS AFTER 2000 REPLACING THE PHOTOMETER BULB HOURS OF USE SERVICE ENG REPLACING THE SAMPLING PROBE AS NEEDED OPERATOR REPLACING THE TUBES Tubes Kit ONCE A YEAR SERVICE ENG ILab 300 Plus Service Manual Rev 03 January 2004 Page 18 Chapter 07 Mantenance PROCEDURE FREQUENCY EFFECTUATED BY REPLACING THE PRE HEATER AND THE AS NEEDED SERVICE ENG SENSOR LEVEL MECHANICAL ALIGNMENT
177. perties Paper Set on A4 Portrait and Tractor in Paper Source Select Graphics and set the 120 x 144 resulution Select Device Options Printer Quality High Speed ON New Instruments 16 Install the I Lab 300 Plus software Insert the auto executable CD Rom In the mask I Lab 300 Plus rel 1 0 8 Multilanguage Setup click on Next There are three choices Complete Upgrade and Service Select Complete Follow the steps ILab 300 Plus Service Manual Rev 02 January 2004 Page 9 Chapter 03 INSTALLATION as required The system will install the MasterSoftware and the MasterHardware Select YES when is asked if maintain the existing files Chose the language 17 Run again the installation program Select Service Install the program TEST ILAB and the program WINZIP 18 Start the ILab 300 Plus program P S Turn on the instrument first The instrument will take a minimum of 10 minutes to reach the correct temperature Meantime it is not possible to run analysis but it is possible to enter the different parts of the software 19 Select the diagnostic program 20 Reset the arm by selecting the Global Setting folder Install the probe 21 Select the Diluter folder and run several time the Probe Wash Test as far as the rinse tube is filled with liquid 22 Select the Configuration folder Type the password 1234 and run the Washing Well Level test to optimize the level o
178. pieces Caps Kit yellow green red Button Kit Kit Tubing peristaltic pump Bearing Reaction Plate Kit Diluter Joints PC Boards Service kit ILab 300 Power Cord Tubes Adapter 20 pcs Head Diluter Joint Joint Diluter 10 Pcs Metal Rings for lev Sens amp pre heater fixing 10 pcs Locknut 10 pcs Level Sensor amp pre heater springs 10 pcs Level Sensor amp pre heater assy lock Key 10 pcs Fuse 6 3x32 10 pcs Joint E V Rinse 10 Pcs Diluter 1000 microl Solenoid Valve 2 way Bottle Sensor Cable January 2004 Rev 02 4 ILab 300 Plus LL Part Number 23350083500 23300019501 23915002000 23100010800 23935004000 23650067800 23990090100 23135000500 23935003100 23935003200 23935004100 23905007800 23F50002000 23350081900 23965003700 23950001000 23500034600 23500035300 23500036500 23500035700 23500035600 23500034700 23500035203 23500034701 23500047000 23500034800 23500034900 23500035000 23500035100 23500035200 23500035201 23500035202 23950003000 23905004200 23905004201 23905004300 23905004400 23905004500 23965003601 23350081600 23910006201 23050040500 23300034200 23910001300 23910006000 23F35001800 23901003800 23350083400 Service Manual Service Parts sorted by Description Description Alignment Electrode Tool Analytical Control Bd Arm Assembly Assy Photometer Bar Code Reader Bar Codes kit ILab 300 Bearing Reaction Plate Belt arm horizzontal Belt arm vertic
179. ple Size and Carry Over Rapid electrolyte results Simple Maintenance Maintenance performed by lab personnel Simple maintenance Reliable sample processing assured High accuracy and precision High accuracy and precision Low cost per test Convenaient maintenance Rev 02 January 2004 Page 3 Chapter 12 Ise Module 12 3 TECHNICAL SPECIFICATION Sample Whole Blood Serum Plasma or Urine Urine requires dilution 1 10 Sample Size Reproducibility Sodium Potassium Chloride Analysis Time Throughput Reagents 70 ul 3 channels serum 160 ul undiluted urine Maximum imprecision within run Typical Carry Over Serum CV 1 596 100 160 mmol L 0 596 CV lt 2 3 00 6 00 mmol L 1 596 CV lt 2 80 0 120 0 mmol L 1 096 Serum 30 seconds including one point calibration Urine 60 seconds including one point calibration Serum 120 sample hour Urine 60 sample hour Calibrant Calibrant B Cleaning Solution Urine Diluent Maximum Environnemental Temperature 38 Host Analyzer requires working temperature within 18 T 32 ILab 300 Plus Service Manual Rev 02 January 2004 Page 4 Chapter 12 Ise Module 12 4 SYSTEM OPERATION ISE THEORY Electrolyte Measurements System measure sodium potassium and chloride in biological fluids using ion selective electrode technology The flow through sodium electrode selective PVC membrane tubing
180. ply wires connected to the Lamp Regulator board by loosening the two screws on the M1 connector Fig 4 Unscrew the lamp s fastening screws and remove it from its housing Unscrew the four fastening screws on the motor support in order to access the filter wheel Position the filter wheel in such a manner as to make it possible to see and unscrew the internal opto sensor support screw Unscrew the external opto sensor support screw Unscrew the optic sensor fastening screws from its support and substitute with the new one Remount the assembly repeating the above steps 12 through 1 in reverse order After remounting reseat the lamp and carry out the electronic adjustment procedures as described in Sections 6 2 3 ILab 300 Plus Service Manual Rev 04 January 2004 Page 36 Chapter 06 SETTINGS AND ADJUSTMENTS 6 2 5 SUBSTITUTION OF THE MOTOR gt N B Make sure the instrument ILab 300 Plus is turned off before performing this substitution procedure Remove the cover panel of the reaction plate Fig 1 Unscrew the four cross bar fastening screws and remove the cross bar Fig 1 Unscrew the 4 fastening screws on the reaction plate assembly Fig 2 T p BIS ure Remove the J1 J2 connectors and the ground wire from the Reaction Chamber Motor Interface board Fig 2 5 Remove the J1 J14 connectors and the ground wire from the Reaction Plate Interface board Fig 2 6 Open the peristaltic pump assembly panel cover Uns
181. presented using the following characters 19950301153500 Legend R Required D Down Load O Optional U Up Load I Ignored N Never A Always S Sometimes Example Header Record Layouts H Download Host HIMN III HOSTIIIIIIIIII9950301153500 CR Upload Analyzer System HIN amp llI SHAnalyzer 111111111 19950301154000 lt CR gt 8 4 PATIENT RECORD P Field Field Title Down Up Max Description and Valid Values Load Load Len Record Type ID R A 1 This is a required field that contains a identifying it as a patient record 2 Sequence Number R A 3 This field starts with a 1 for the patient and is incremented by 1 for each additional patient within the transmission 3 Practice Assigned R A 15 This field can be assigned by the Patient ID instrument with no corresponding download 4 Laboratory I N Assigned Patient ID 5 Patient ID No 3 I N ILab 300 Plus Service Manual Rev 03 January 2004 Page 5 Chapter 08 Host Communication 6 Patient Name 5 36 field has two components e Last Name up to 20 characters e First Name up to 15 characters 7 Mother s Maiden I N Name 8 Birth Date 5 8 Formatted as YYYYMMDD For example a birth date of December 1 1980 would be represented as 19801201 9 Patient Sex R A 1 The valid values are e M for Male for Female 10 Pa
182. pressed in tenths of millimeters Repeat step d several times each time returning to the Vertical Home position Make sure that the level indicated remains constant 10 1 mm Repeat steps b to e for positions 8 and 16 of the first rack using the same sample cup Make sure that the difference between all the positions is Imm Repeat steps b to f for samples racks three and five Stat positions 1 8 14 Press the Back to Wash Well key and then select Go Sample in order to allow the probe to return to a position in the rack which does not contain any cup Select Go Level and make sure that the level reached is the maximum indicated in the given window is 9999 Select the Reset key remove the cups from the racks and exit the program by pressing the Diagnostic key To exit the analyzer program press shutdown key ILab 300 Plus Service Manual Rev 04 January 2004 Page 26 Chapter 06 SETTINGS AND ADJUSTMENTS 6 1 6 DILUTER MODULE 6 1 6 1 Substitution of the diluter module N B Make sure the instrument ILab 300 Plus is turned off before performing this procedure 1 Remove the samples and reagents protective covers Fig 1 2 Remove the samples rack and reagents rack 3 Remove the teflon tube on the diluter head by unscrewing the fastening washer Fig 2 paying special attention to leakage of liquid 4 Unscrew the four anchored screws indicated in Fig 2 unplug the J6 J8 and J13 connectors
183. py Disk 3 1 2 1 44 Mb Colour SVGA 15 low radiation MONITOR Resolution 800 x 600 pixels max number of colors 65536 16 bit 80 Columns impact graphic EPSON LX 300 PRINTER PS2 INTERFACE Two Bi directional RS 232C serial ports and one parallel Multitasking WINDOWS 98 SOFTWARE Italian English Chinese Czech Software to be released AVAILABLE LANGUAGES soon in these languages Russian Portuguese French Polish Upon request it is possible to release the software in other languages SETTINGS Disable all the energy saving options Disable the screen saver Select English USA as language Select date and time in Regional setting 99 9 NOTE Even though the computers demonstrate the same technical and operative characteristics some of these could have different hardware installed This could cause problems for the ILab 300 Plus software when running tests A message appears indicating Random error or blocks the program Therefore if the PC is bought separately locally it is highly recommended to test the system at your offices before preceding with the installation at the final client s Consequently AMS denies any responsibility for software problems that are due to buying the computer separately from the instrument 1 4 2 Options ISEMODULE POSITIVE BARCODE READER 1 4 3 Dimensions Weight amp Environment Height 42 cm DIMENSION Depth
184. r STAT Indicator READY Indicator turning green when the button is not pushed in and red if it is 5 1 STATUS BAR Monitors the instrument s status while the program is running Fig 5 Fig 5 Diagnostic C 29 May 03 Firmware Rel STAT Status Indicator Date Instrument Status ST BY Status Indicator READY Status Indicator Start Stop Diagnostics ILab 300 Plus Service Manual Rev 02 January 2004 Page7 Chapter 05 DIAGNOSTIC PROGRAM 52 TEST FOLDER The following is a summary of each individual test folder function The ILab 300 Plus s diagnostic program is subdivided into 12 folders Arm Diluter Optic Plate Temperature Wash User Miscellaneous Global Setting Macro Setting Configuration ISE ILab 300 Plus Service Manual Rev 02 checks if the arm is functioning correctly checks if the diluter is functioning correctly checks if the optical block is functioning correctly checks if the reaction plate is functioning correctly checks the temperature of the pre heater and reaction plate checks if the wash station is functioning correctly checks if the user functions are working properly performs general checks the adjustment of the arm position can be checked the operator can identify which macros have been loaded Through the use of a password only qualified technical personal can adjust certain parameters This file is not accessible to the Labo
185. r J6 from the Reaction Plate Interface board Fig 2 Remove the magnet and substitute it with the new one vaio og Remount repeating the above steps 6 through 1 in reverse order 6 5 5 2 SUBSTITUTION OF THE CUVETTE HOLDER ASSEMBLY SENSOR N B Make sure the instrument ILab 300 Plus is turned off before performing this substitution procedure Remove the reaction plate cover Fig 1 Remove connector J5 from the Reaction Plate Interface board Fig 2 Remove the optic sensor s two fastening screws and substitute it with the new one Fig 7 Remount repeating the above steps 3 through 1 in reverse order Pt pb pa ipu After substituting and remounting carry out the mechanical adjustment procedures as described in section 6 5 5 3 ILab 300 Plus Service Manual Rev 04 January 2004 Page 55 Chapter 06 SETTINGS AND ADJUSTMENTS 6 5 5 3 ADJUSTMENT AND FUNCTIONAL CHECK OF THE CUVETTE HOLDER MAGNETIC TRIGGER gt N B Make sure the instrument ILab 300 Plus is turned off before performing this substitution procedure 1 Loosen the screw on the cuvette holder trigger Fig 7 2 Rotate the reaction plate in such a manner as to position the trigger between two cuvettes Fig 8 3 Manually push the pin toward the center of the solenoid simulating magnetic attraction between the two 4 Position the trigger in such a manner that the top edge is at the same height as the top edge
186. r can calculate the concentration of the ions in the sample solution in accordance with the Nerst equation rewritten as S log C4 C or 10 E E S ILab 300 Plus Service Manual Rev 02 January 2004 Page 5 Chapter 12 Ise Module Where E ISE potential developed in sample solution E ISE potential developed in the Calibrant solution S Hlectrode slope calculated during calibration C Concentration of ion in the sample C Concentration of ion in the Calibrant solution S the slope is determined during calibration using Calibrants A and B which have known levels of sodium potassium and chloride When an automatic calibration is initiated the slope is calculated between the second Calibrant A reading and the Calibrant B reading Excessive drift or noise reading will be flagged and the appropriate error message sent to the host analyser from the ISE Module 12 5 MECHANICAL FEATURES The electrode housing contains each of the ion selective electrodes as well as the reference electrode Two bubble detectors are also included at both the top and bottom of the electrode chain These are used to properly position the sample for measurement A sample port is positioned directly above the chain of electrodes on the top of the module An electronic signal processing board is attached to the electrode housing This board includes high input impedance operational amplifiers to detect the ISE si
187. r cuvettes replacement See fig 2 To avoid the temperature probe damage be sure that its wires do not interfere with the reaction plate rotation By executing the reaction plate Reset the cuvettes 45 and 46 will be accessible through the small door so allowing the following operations a Pre warm the micropipette tip by repeatedly aspirating and dispensing the liquid from into the 250 500 ml container Put 300 uL of distilled water pre warmed at 37 0 37 3 C into the cuvettes 45 and 46 b Wait 2 3 minutes then enter in the Temperature Folder and select Temp Test Run c Measure the temperature by dipping and gently shaking the temperature probe into the liquid in the cuvettes d Take note about the measured temperatures Note 2 The reaction plate temperature must be set at 37 0 37 2 C ILab 300 Plus Service Manual Rev 04 January 2004 Page 61 Chapter 06 SETTINGS AND ADJUSTMENTS e If necessary modify the value in the PLATE parameter field Configuration Folder in the Diagnostic Program by taking into account that 7 COUNTS CORRESPOND TO ABOUT 1 C If the difference should be higher than 2 C wait a few more minutes and repeat steps a b c d e f Close the main cover and after having checked the correct setting of the reaction plate temperature select Temp Test Run in the Temperature Folder inside the Diagnostic program g Verify that the temperature probe or others
188. ratory operator Checks if the ISE Module is functioning properly and allows the operator to do maintenance or repair operations January 2004 Page 8 Chapter 05 DIAGNOSTIC PROGRAM 3 3 FOLDER ety Wash Station Filter Wheel Cover Lack S qm pe Ex Am Smp Smp2 3 Smp4 STAT Ready Diagnostic E o E Diagnost istic Warning the improper use of the functions described in this folder can damage the sampling probe The Arm File is subdivided into four areas VERTICAL HORIZONTAL STATUS COMMAND SETTING 300 Plus Service Manual Rev 02 January 2004 Page9 Chapter 05 DIAGNOSTIC PROGRAM 5 3 1 VERTICAL COMMAND AREA 5 commands Home Down Well Up Down Go Level Brings the arm vertically to a home position Brings the arm s axis Z to the height of the well Raises the arm tenths of a millimeter as preset in the square found immediately on the right Lowers the arm tenths of a millimeter as pre determined by the square found immediately on the right Brings the probe to either the reagent level the sample or the standard and reads the level Before giving this command it is necessary to set the parameter for the probe s maximum lowering level in the max area mm 5 3 2 HORIZONTAL COMMAND AREA 7 commands Back to wash well Brings the
189. rence thermometric probe Service probe The offset value that has been previously inserted and the temperature value read by the thermometric probe appear in the closed fields Cursore To enter the offset value 3 C The offset value will be zero after exiting from the folder 5 7 5 TEMPERATURE TEST AREA 3 commands Temperature Test mm START To perform the test check and to regulate the temperature of the preheater and of the reaction plate by using the kit P N 23550120400 as illustrated in Chapter 6 Setting and Adjustments The number of sample cycles are predefined whereas the reagent and sample positions for test execution can be selected by the operator Service Probe the field in which the temperature of the service probe appears ILab 300 Plus Service Manual Rev 02 January 2004 Page 20 Chapter 05 DIAGNOSTIC PROGRAM WASH To run a wash cycle on the cuvettes used for testing EXIT To exit from the Temperature Test box and to run a wash cycle on the cuvettes if they have been used 5 7 4 STATUS COMMAND AREA Send Visualizes the commands sent by the program to the instrument hardware Receive Visualizes the instrument hardware s response to the commands sent by the program 5 8 WASH FOLDER DIAGNOSTIC Eu pepe EE The Wash folder is subdivided into four areas OPERATIONS SENSOR STATUS TEST STATUS COMMAND ILab 300 Plu
190. rent pathway flow diagram PWM control TA 8435 H controls PWM placing the upper transistor in an on off switching mode In this case current flow is as illustrated below DRIVE CURRENT Q1 ON 02 OFF Q3 OFF Q4 ON e RECIRCULATION Q1 OFF 02 OFF Q3 OFF Q4 ON ILab 300 Plus Service Manual March 2003 Rev 01 Page 21 Chapter 2 GENERAL DESCRIPTION Control of the output current via the detection resistor of the output and input current REF IN the motor current maximum current for micro step piloting I is regulated as shown in the following equation using the REF IN in put and the detection resistor of the external current RNF Io Vrer Where for REF IN HIGH gt VREF 0 8 V for REF IN LOW VREF 0 5 CONTROL LOGIC Clock input for rotation direction control To switch the rotation direction from forward to backward there are two clock inputs CK1 and CK2 and input CW CCW and the first of the two control methods are shown in the diagram below 1 2 STEP PILOTING The selection between full step 1 2 step 1 4 step and 1 8 step is carried out with binary coding on the two 1 and M2 inputs ILab 300 Plus Service Manual March 2003 Rev 01 Page 22 Chapter 2 GENERAL DESCRIPTION 2 5 3 SAMPLING INTERFACE ASSY The Sampling Interface Assy board controls the arm the diluter the pre heater and wash well liquid leakage The Home Sensors vertical external arm internal
191. ress shutdown key 6 1 6 5 BACKLASH ILab 300 Plus Service Manual Rev 04 January 2004 Page 28 Chapter 06 SETTINGS AND ADJUSTMENTS BACKLASH ADJUSTMENT By adjusting the Backlash we are able to compensate the backlash of the diluter Enter the ILab 300 Plus software Select Diagnostic Select the Global Setting folder to reset the Arm Select the Diluter folder Run the Probe Wash Test twice Select the Arm folder Move the probe in the Diluter position GO DIL Return back to the Diluter folder GN OA PUE et am Optic Piste Temperature Wash User Miscellaneous Global Seting macro seting Contguetan sE Operations Sensor Status Status Command Hama Dilwter NotHome E E ul e Probe Yash Test 1 Reaction Wash Station Lesk Hame Sensor Rack Daor Liquid Alarm WoshStoion f CoverLock CmessisBase Pite Waste wosa 2 pedo cw ede eas T Micro 2 Arm Diluter Sansor Rack Doar Leak Liquid Alam Frontpanal buton int em Door f Pinse Deer Ste GAT Ex Am Smp3 Emp STAT een Ready Disgnostic 24 12n 03 Diagnostic 9 Home the Diluter 10 Prepare a sample cup filled with deionized water 11 Set up the cursor at 300 MicroL 12 By ke
192. rg Fluidic Valve 2 Ways W P Fluidic Valve 3 Ways W P Front Panel Switch assembly Fuse 6 3x32 10 pcs Fuse Holder Kit Gasket compression Gauge Peristaltic Pump Joint Bottles Rinse Water Cleaning Joint Diluter 10 Pcs Joint E V Rinse 10 Pcs Halogen Lamp Head Diluter Joint Head Tube Perilstatic Pump Home Sensor Assemby vertical Horizzontal Home Sensor Assembly filter wheel reaction plate washing station Hydraulic Interface Bd Inlet Sample Pot Assy Interconnecting Serial Cable 9 Pin 5m Interferential filters Kit Photometer Interlock Assy Interlock Switch Ise Connection Tube 6mt Ise Control Board Ise Module Kit Diluter Joints Kit Measurament Temperature kit Ise Module Kit Tubing peristaltic pump Label Index Board Lamp P W S Board Lamps kit 5 pieces Level Sensor amp pre heater assy lock Key 10 pcs Level Sensor amp pre heater springs 10 pcs Level Sensor and Pre heater Assy Locknut 10 pcs Lower Kit Gasket Main Power Socket Metal Rings for lev Sens amp pre heater fixing 10 pcs Micro Pump 2 Micro Pump 3 Micro Pump 4 Micro Pump Assembly Probe rinse Motor Cable Motor Plate Interface Bd Motors Assy for S Arm P Pump O Ring 4 Pcs January 2004 Rev 02 ILab 300 Plus LL Part Number 23350083700 23650022702A 23100028601 23350082000 23350082700 23350081500 23AS620005 23935003401 23300010700 23300010703 23300010705 23350082800 23350082900 23300044600 2
193. rial under the sampling arm and under the wash station group gt Tape down using masking tape if possible the cover of the samples and reagents housing the front panels and the samples and reagents racks gt Remove the probe from the sampling arm and place it inside a cuvette Then cap the cuvette and tape the cap down Be very careful to not bend the wash station cannulas when repositioning the protective packing material gt the empty spaces around the accessories packed in the crate using pluriballs or other suitable packing material ILab 300 Plus Service Manual Rev 02 January 2004 Page 3 Chapter 03 INSTALLATION 32 INSTALLATION The ILAB 300 PLUS must only be installed by a qualified technician who has been authorised and trained to do so During its installation the system will be checked once again to ensure correct functioning The persons who are required to operate the ILAB 300 PLUS system must have received the adequate training This should also include the know how of the normal maintenance for the instrument A description of the maintenance will be found in Chapter 7 of this manual ILAB 300 PLUS is a complex system and it is therefore extremely important that it is correctly installed in order to fully guarantee fine performance If the installation and use directions given in this manual are not correctly followed and or security indications are not respected AMS cannot guarantee
194. robe freely Select the Arm key and then Go Sample Set Samples position 16 Make sure that the Pre heater cable does not hinder the arm while it is in movement If this situation should occur turn the Pre heater cable counter clockwise in order to optimize the assembly Press the Reset key To exit the diagnostic program press the Diagnostic key To exit the analyzer program press the Shutdown key Fig 1 Probe Assembly PN 23910006201 23 cm Intermediate cable guide guide Front cable guide a Fig 2 ILab 300 Plus Service Manual Rev 04 January 2004 Page 22 Chapter 06 SETTINGS AND ADJUSTMENTS Kit for E V Diluter connection PN 23990090600 Fastening screw Fig 3 Metal rings for level sensor and pre heater assy fixing PN 23C101023000 Removal of the Metal rings Fig 5 ILab 300 Plus Service Manual Rev 04 January 2004 Page 23 Chapter 06 SETTINGS AND ADJUSTMENTS Level sensor and pre heater spring PN 23C101023600 Locknut for pre heater assy PN 23C101023200 Fig 6 Level sensor and pre heater assy locking key PN 23C101057200 Fig 7 ILab 300 Plus Service Manual Rev 04 January 2004 Page 24 Chapter 06 SETTINGS AND ADJUSTMENTS 6 1 5 2 Level Sensor functioning Check 1 Turn on the 300 Plus system instrument and computer 2 Remove the protective cover of the samples rack Touch the sampling probe with your
195. rom its housing 2 Remove the samples and reagents racks protective covers Fig 1 3 Remove the samples rack and reagents rack 4 Unscrew the four cross bar fastening screws Remove the cross bar by slipping out the Pre heater guide support Fig 1 Remove the waste tube from the wash well and the teflon tube on the diluter 6 Unscrew the four anchored screws indicated in Fig 5 unplug the 11 J2 JIS and J17 connectors from the Sampling Interface assy Fig 5 Disconnect the ground wire and remove the sampling arm ILab 300 Plus Service Manual Rev 04 January 2004 Page 9 Chapter 06 SETTINGS AND ADJUSTMENTS 6 1 3 2 a Substitution of the OS6 Opto sensor a Remove the screws which fasten the opto sensor support and take out the entire assembly Fig 6 b Unplug the J10 connector from the Sampling Interface assy remove the opto sensor fastening screws and substitute it with the new one c To remount repeat the above steps in inverse order from b to a and then from 6 tol in Section 6 1 3 2 Warning Do not tighten the protective cover s set screw as this could result in mechanical malfunction of the sampling arm s vertical movement Fig 2 N B when remounting the opto sensor make sure to center it with respect to the slots as shown in Fig 4 Warning After having substituted the opto sensor it is necessary to mechanically align the robe with respect to the wash well and center all th
196. rvice Manual Rev 04 January 2004 Page 34 Chapter 06 SETTINGS AND ADJUSTMENTS 13 Select the filter positions from 1 to 8 from 340 nm to 620 nm and click on Start Stop Sample Channel Conversion key and determine which filter transmit the highest signal 14 Verify in the adjacent window a count value of 55 000 1000 If not adjust the Preamp ADC board Gain trimmer inside the analysis plate in order to set the desired value Fig 5 15 After regulating the Gain select all the other filters and clicking on Start Stop Sample Channel Conversion verify count values between 29000 and 56000 Warning Room lighting and daylight can influence the reading To avoid this interference replace the reaction plate cover panel before carrying out any check procedures 16 Select the highest signal filter identified in point 13 Click on Start Reference Channel Conversion and make sure that the adjacent window shows a count value of 40 000 1000 If not adjust the Preamp ADC board Gain trimmer external to the analysis plate in order to set the desired value Fig 5 17 After regulating the Gain select all the other filters and clicking on Start Stop Reference Channel Conversion verify count values between 29000 and 41000 18 After concluding these operations empty cuvette 31 and exit the diagnostic program by clicking on the Diagnostic key 19 Exit the analyzer program press shutdown key Fig
197. s Internal Arm s O S External Arm s Diluter turn green when the relative device is in the Home position and turn red when the relative device is not in the Home position The following fields signal the presence of the rack in the appropriate home position reagents samples standard and controls Sample1 Rack s O S Sample2 Rack s O S Sample3 Rack s O S Sample4 Rack s O S Sample 5 Rack s O S STAT turn green when the rack is in the appropriate home position and turn dark gray when the rack is not present not inserted The field below signals the general door opening of any of the racks Rack Door s O S turns red when the door is open and green when the door is closed The field below signals the 300 Plus s arm leak alarm Arm Leak Alarm turns green if there is no leaking and red if there is ILab 300 Plus Service Manual Rev 02 January 2004 Page 6 Chapter 05 DIAGNOSTIC PROGRAM The following fields check the liquid level of the distribution loading bottles Rinse Level Alarm Distilled Water Level Alarm Cleaning Level Alarm turning green if the liquid level is above the predetermined minimum limit and red if the liquid quantity is below the predetermined minimum level the bottle is almost empty The following fields signal the state of the button on the Lab 300 Plus s operator panel ST BY Indicato
198. s Service Manual Rev 02 January 2004 Page 21 Chapter 05 DIAGNOSTIC PROGRAM 5 8 1 OPERATIONS AREA 2 commands Home Down Brings the washing device to the Home position Makes the washing device go down to the washing position 5 8 2 SENSOR STATUS AREA In this area the sensor state of the wash station is indicated 5 8 3 TEST AREA 4 commands Test E V 1 Test E V 3 Test E V 5 Peristaltic Pump Performs the solenoid valve 1 test Performs the solenoid valve 3 test Performs the solenoid valve 5 test Starts the peristaltic pump and automatically turns off after a period of tiis predetermined by the user 5 8 4 STATUS COMMAND AREA Send Receive Visualizes the commands sent by the program to the instrument hardware Visualizes the instrument hardware s response to the commands sent by the program 5 8 5 SENSOR STATE TEST STATUS COMMAND ILab 300 Plus Service Manual Rev 02 January 2004 Page 22 Chapter 05 DIAGNOSTIC PROGRAM 5 9 USER FOLDER DIAGNOSTIC Cover Lack Chassis Base Plat The User File is subdivided into three areas USER TEST MICRO 1 USER TEST MICRO 2 STATUS COMMAND ILab 300 Plus Service Manual Rev 02 January 2004 Page 23 Chapter 05 DIAGNOSTIC PROGRAM 5 91 USER TEST MICRO 1 AREA 1 command Main Cover Lock ON OFF Alternatively turns on or off the solenoid valve holder and releases
199. s necessary to achieve a compromise in order to obtain the best results doing BIB and BIC testing as indicated in the following procedure Precision check of the Analytical plate BIB Prepare two series of 32 samples each by using K2Cr207 0 04 gr l starting from 4 gr l concentrated solution and dilute 1 100 Use the same solution for both samples and reagent Program a new method with the following parameters Method name BIB Type End Point Sample volume K2Cr207 0 04 gr l 3uL Reagent volume K2Cr207 0 04 gr l 300 uL Filter 340 nm Incubation time 116 sec Calculation factor 1000 BIB Procedure 1 Select conical cup in Options 2 Program the BIB method using the above parameters and configure a reagent rack containing it 3 Enter in the calibration screen and select RBL for BIB method 4 Put RINSE SOLUTION as reagent and sample fourteenth position and Start the Calibration 5 Program 64 BIB fill 32 conical samples cup with K2Cr207 0 04 gr l 6 Load the racks on sample positions 1 and 2 of the Analyzer 7 Substitute the RINSE SOLUTION with K2Cr207 0 04 gr l on the reagent rack 8 Start the Analyzer At the end of the last sampling move the sample racks into positions 3and 4 ILab 300 Plus Service Manual Rev 02 January 2004 Page 34 Chapter 05 DIAGNOSTIC PROGRAM The mean value for each of the 32 sample series must be within 360 400 The coefficient of variation percentage CV 96 must be lower than 0 7 for each series of 32
200. screw the four anchored screws of the reaction plate module Fig 2 BR WwW N Remove the Jland J3 connectors and the ground wire from the Reaction Chamber Motor Interface Fig 2 5 Remove the J1 J3 J5 J6 714 connectors and the ground wire from the Reaction Plate Interface Fig 2 6 Remove the top cover of the washing station using the special tool supplied by the manufacturer Fig 5 7 Disconnect the seven tubes attached to the probes on the washing station Fig 6 8 Remove the reaction plate from the instrument 9 Unscrew the four fastening screws on the washing station assembly Fig 3 10 Remove the washing station assembly and replace it with the new one 11 Remount repeating the above steps 10 through 1 in reverse order 12 After substituting and remounting carry out the mechanical adjustment and functional check procedures as described in section 6 5 4 Reaction plate cover Fig 1 ILab 300 Plus Service Manual Rev 04 January 2004 Page 50 Chapter 06 SETTINGS AND ADJUSTMENTS Reaction tray interface PN 23300019301 Motor plate interface board PN 23300034100 Fig 2 Reaction Plate assembly PN 23910006101 Reaction Plate assembly is supplied without Washing Station and Photometer OS4 Opto coupler assy is PN 23910002300 Motor support EH z Washing station fastening screw il 7 Mechanical Joint screws Flywheel screw Stepper Motor washing probes PN 2
201. t during which the modules Sampling Arm Reaction plate Washing Station and Photometer are moved to all the different positions The correct modules positioning is also automatically verified and showed on the following table ILab 300 Plus Service Manual Rev 02 January 2004 Page 26 Chapter 05 DIAGNOSTIC PROGRAM Meccanical Test D Ai Go Reagent 22 OK Down 400 Step OK Vertical Home OK Go Home OK Go Sample or Std Ctil Std 5 OK Down 400 Step OK Vertical Home OK Go Home OK Move Cuvette to Disp 31 OK Go Disp Down 400 Step Vertical Home Go Home Move Cuvette to Optic Down Wash Home Wash Exit Test To stop the test push on the Exit Test key 5 10 5 SENSOR STATUS AREA 1 command Sensor Polling To choose either Polling ON or Polling OFF When in the Polling ON position it is possible to check the functionality of the optical filters in various positions 5 10 6 STATUS COMMAND AREA Send Visualizes the commands sent by the program to the instrument hardware Receive Visualizes the instrument hardware s response to the commands ILab 300 Plus Service Manual Rev 02 January 2004 Page 27 Chapter 05 DIAGNOSTIC PROGRAM 511 GLOBAL SETTING FOLDER Seung OF Warning the improper use of the functions described in this folder can damage the sampling probe The Global Setting Folder is subdivided int
202. the main cover lock 5 9 7 USER TEST MICRO 2 AREA 3 commands Alarms ON OFF Turns on and off the STAT indicator lamp Ready ON OFF Turns on and off the READY indicator lamp Test BUZZER Performs a complete operational test of the buzzer 5 9 5 STATUS COMMAND AREA Send Visualizes the commands sent by the program to the instrument hardware Receive Visualizes the instrument hardware s response to the commands sent by the program ILab 300 Plus Service Manual Rev 02 January 2004 Page 24 Chapter 05 DIAGNOSTIC PROGRAM 5 10 MISCELLANEOUS FOLDER The Miscellaneous folder is subdivided into six areas General Reset Sensor Checking Log Raw data Continuous Test Run Sensor Status Status Command ILab 300 Plus Service Manual Rev 02 January 2004 Page 25 Chapter 05 DIAGNOSTIC PROGRAM 5 10 1 GENERAL RESET AREA 1 command Reset Performs the resetting of the general system 5 10 2 SENSOR CHECKING AREA 2 commands Plate 1 Step To turn the reaction plate in a counter clockwise direction to check the home sensor Plate 1 Step To turn the reaction plate in a clockwise direction to check the home sensor 5 10 3 LOG RAW DATA AREA 1 command Enable To save a copy of the files for the technical diagnosis if the instrument malfunctions The files are memorized in the folder Log inside the folder Analyzer 5 10 4 CONTINUOUS TEST RUN 1 command Start Test Performs an automatic tes
203. the hole in the Samples Cover 9 Move on to the next position by pressing the Next key and center the probe as above 10 Make sure that when adjusting position 16 mechanical end of run of the arm does not occur If this should happen repeat the mechanical alignment of the sampling probe with respect to the wash well and repeat the procedure from step 4 1 Press Save to memorize the new positions settings ILab 300 Plus Service Manual Rev 04 January 2004 Page 5 12 13 14 15 16 17 18 6 1 2 Chapter 06 SETTINGS AND ADJUSTMENTS Select Reagent from Setting of and then press the Go key The arm will automatically move itself to position 1 of the Reagents rack Adjust the positioning by using the keys indicated for centering the probe with respect to the hole in the Reagents Cover Move on to the next position by pressing the Next key and center the probe as above Make sure that when adjusting position 33 mechanical end of run of the arm does not occur If this should happen repeat the mechanical alignment of the sampling probe with respect to the wash well and repeat the procedure from step 4 Press Save to memorize the new position settings Set the positioning of Std Ctrl and Dil Ise Disp Press Save to memorize the new position settings To exit the diagnostic program press the Diagnostic key To exit the analyzer program press shutdown key SUBSTITUTION OF THE SAMPL
204. tient Race Ethnic I N The Analyzer System will ignore this field Origin at launch 11 Patient Address 5 60 For Analyzer this is a four component field e Address 25 characters e City 25 characters e State 2 characters e g NY IT e Zip 5 characters 12 Reserved Field I N 13 Patient Tel Number I N 14 Attending Physician I N ID 15 Special Field 1 I N 16 Special Field 2 I N 17 Patient Height I N 18 Patient Weight I N 19 Patient Known or I N Suspected Diagnosis 20 Patient Active I N Medications 21 Patient s Diet I N 22 PPractice Field No 1 I N 23 Practice Field No 2 I N 24 Admission Date 5 8 ldmission date only Discharge Date if Formatted as YYYYMMDD desired 25 Admission Status I 26 Location S 20 ILab 300 Plus Service Manual Rev 03 January 2004 Page 6 Chapter 08 Host Communication 27 Nature of I N Alternative Diagnostic Code and classifiers 28 Alternative I N Diagnostic Code and classification 29 Patient Religion I N 30 Marital Status I N 31 Isolation Status I N 32 Language I N 33 Hospital Service I N 34 Hospital Institution I N 35 Dosage Category I N Legend R Required D Down Load O Optional U Up Load I Ignored N Never A Always S Sometimes Example Patient Record P Download Host P 1 B108K I MW5910 Smith 19861002 I M I I Park Avenue New York NY 10002 11 111111112002092
205. tly to push the new Tip into place be careful to not press too hard as this could deform the Tip 5 Insert the cannula containing the new Tip into a cuvette pushing it down inside until it takes on the shape of the inside of the cuvette 6 Remove the cuvette connect the aspiration tube to the cannula and reposition the cannula back into its proper housing in the wash station Be careful to not kink the aspiration tube while doing so 7 Reposition the spring in its proper housing Remount the wash station coverlid making sure that the cylindrical tops of the cannulas fit into the corresponding holes on the wash station coverlid IMPORTANT Before starting the instrument back up manually move the wash station upwards as far as it will go Pull to remove the used Tip Push the new Tip into the cuvette ILab 300 Plus Service Manual Rev 03 January 2004 Page 11 Chapter 07 Mantenance 77 HYDRAULIC CIRCUIT WASHING During normal use and over time mold and dust can build up inside the wash bottles and can have a negative effect on the hydraulic circuit compromising the correct functioning of the micro pump and valves This in turn can lead to inefficiency in the sampling probe and cuvette washing system For this reason it is extremely important that the hydraulic circuit be periodically washed Said cleaning must be thorough and meticulous in order to assure that every trace of mold or residue be removed How often
206. to mechanically align the probe with respect to the wash well and center all the other positions by following the procedures provided in Section 6 1 1 Alignment and Adjustments 6 1 4 SAMPLING ARM MOTORS N B Make sure the instrument ILab 300 Plus is turned off before performing this procedure Important pay special attention to the Pre heater when removing or servicing the sampling arm In order to arrive at the M7 M6 and M5 motors it is necessary to remove the sampling arm assembly from its housing unplug the 11 J2 J3 J4 J5 J15 and J17 connectors from the Sampling Interface assy disconnect the hydraulic tube from the wash well and the teflon tube on the diluter remove the four anchored fastening screws from the assembly ILab 300 Plus Service Manual Rev 04 January 2004 Page 12 Chapter 06 SETTINGS AND ADJUSTMENTS 6 1 4 1 Substitution of the M7 motor etre Ny ee a 10 11 12 13 14 Remove the sampling probe Remove the samples and reagents racks protective covers Remove the samples rack and reagents rack Unscrew the four cross bar fastening screws Remove the cross bar by slipping out the Pre heater guide support Fig 1 Remove the waste tube from the wash well Remove the teflon tube on the diluter head by unscrewing the fastening washer pay particular attention to leakage of liquid Unscrew the four anchored screws indicated in Fig 3 unplug the J1 J2 J4
207. tools are correctly positioned so to avoid their interference with the moving parts of the instrument During this procedure step in fact the Sampling arm the washing Station and the Reaction Plate will become active h By pressing START the system will sample seven reaction cuvettes in sequence i At the end of the sampling cycles the main cover will be unlocked j Open the small door for cuvettes replacement Measure and take note of the cuvettes temperature starting from the seventh up to the first cuvette by dipping and gently shaking the temperature probe into the liquid k Atthe end of measurements press WASH The system is ready for a new cycle Note 3 The measure obtained from the seventh cuvette is the best indication of the pre heater temperature The measure obtained on the first cuvette is the nearest to the reaction plate temperature previously adjusted to 37 0 37 2 The objective is to obtain the same temperatures into all the seven cuvettes 37 37 2 C l If necessary modify the value in the ARM parameter field Configuration Folder in the Diagnostic Program by taking into account that 7 COUNTS CORRESPOND TO ABOUT 1 m After any modification in the Parameter values repeat the steps from f through ILab 300 Plus Service Manual Rev 04 January 2004 Page 62 Chapter 06 SETTINGS AND ADJUSTMENTS n At the end of the adjustment procedure get out from the Diagnostic Program and from
208. trols phase excitation frequency the pilot mode depends on the pin 8 and M2A pin 9 inputs set via the SWIDIP SWITCH according to the following table L off 1 4 step default setting Please note that the other clock input pin 7 is connected to the 5 volts Use of the 1 4 and 1 2 steps with respect to the full step make it possible to lessen vibration and improve positioning accuracy A power section made up of 2 Hshaped bridges that generates the voltage to be applied to the two stepper motor windings AM62 AM62N BM62 BM62N respectively on pins 23 20 19 and 16 on connector J1 The latter are supplied when the RES signal is high and the ENA signal coming from the control board via connector J4 is at a low logic level The state of the ENA signal level and therefore that of the relative Stepper Motor driver is indicated by the yellow D17 LED The D1 D3 D5 and D7 Schottky diodes are to protect the internal power circuits ILab 300 Plus Service Manual March 2003 Rev 01 Page 19 Chapter 2 GENERAL DESCRIPTION A power control and monitoring section which via the C5 3 3nF condenser generates a circa 60 kHz internal oscillation frequency used to control the Pulse Width Modulation PWM Said control is affected by the voltage levels produced by the potential drop on the R1 and R2 power resistors present on pins 21 and 18 the PDA pin 10 signal arriving from the control board via conn
209. uvette 16 31 and 46 11 To exit the diagnostic program press the Diagnostic key 12 Carry out the Glucose test on seven samples using distilled water for sample and reagent 13 Press Start and once the seventh sample has been dispensed press Stop Wait the sound signal from the analyzer that means the actual stop 14 Insert the temperature probe all the way to the bottom of the cuvette in which the sampling probe is dispensing Make sure the temperature registered is 37 0 C 0 2 0 3 15 If not launch the Diagnostic program and select the Configuration function 16 Digit the password 1234 in the appropriate window and press OK ILab 300 Plus Service Manual Rev 04 January 2004 Page 58 Chapter 06 SETTINGS AND ADJUSTMENTS 17 Move the cursor within the Heater window to select the desired temperature and then click on Save to memorize said temperature 18 Remove the temperature probe from the cuvette and exit from the Diagnostic program 19 Carry out a washing cycle from Start Work mask in order to clean the cuvette 20 To exit the Analyzer program press Shutdown key N B counts increase correspond to temperature decrease counts decrease correspond to temperature increase seven counts correspond to about one degree centigrade 6 6 2 TEMPERATURE CHECK AND ADJUSTMENT USING KIT P N 23550120400 IMPORTANT NOTICE BEFORE APPLYING THE FOLLOWING PROCED
210. w named Report will appear click OK 12 Exit by clicking on Quit key and click to confirm 13 Click on the Write Confirm red button to transfer the setting data on the Micro 2 When the Write Confirm red button disappears this means that the data transfer has been completed 14 Remove the short circuit from the pins 1 and 2 on the J4 connector on the Analytical Control Board P N 00195 01 15 Click on the HW Reset key and verify a sound signal from the Analytical Control Board to confirm that the firmware upgrading procedure has been successfully completed 16 Click on the Exit key in order to close the application ILab 300 Plus Service Manual Rev 02 January 2004 Page 12 Chapter 03 INSTALLATION TestILAB new Graphic Interface Vers 1 0 TEST x Status Modules Parameters Firmware Reset RUN Am Download Upload Down load tal Exit Read Dwnl Software Plate The functionality of the keys for the updating of the firmware is not changed Under the box called FIRMWARE there are the Download Read Download and Write Conf Keys These buttons maintain the same operative sequence as in the former version Following are the improvements Parameters introduces two functions e Upload which enable to read the system setting parameters from the Micro Arm and Micro Plate Th
211. weling or gauze See Procedure 7 3 ILab 300 Plus Service Manual Rev 03 January 2004 Page 2 Chapter 07 Mantenance TABLE A MAINTENANCE SCHEDULE FREQUENCY PROCEDURE NOTES EVERY TWO WEEKS Clean the Wash Station s four See Procedure 7 4 cannulas EVERY TWO WEEKS Clean the wash solution bottles See Procedure 7 5 Rinse Water and Cleaning ONCE A MONTH Clean the Tip See Procedure 7 6 ONCE A MONTH Clean the Hydraulic Circuit See Procedure 7 7 EVERY TWO MONTHS Change the Reaction Cuvettes See Procedure 7 10 EVERY SIX MONTHS Change the Peristaltic Pump Tubes See Procedure 7 8 EVERY SIX MONTHS Change the Porous Pad See Procedure 7 6 ONCE A YEAR Change all the tubes Tube Kit See Procedure 7 11 YEARLY OR EVERY 2000 Change the Photometer lamp See Procedure 7 9 HOURS e the above described maintenance schedule refers to that situation in which the workload of the Analyzer is approximately 500 tests per day The interval frequency may vary according to the individual instrument s daily workload ILab 300 Plus Service Manual Rev 03 January 2004 Page 3 Chapter 07 Mantenance 7 2 LIST OF PARTS SUBJECT TO WEAR AND USAGE Description Type Quantity Code Kit tubing peristaltic pump Bes 23965004000 Reaction cuvettes 60 23965003100 Drying Pad 23
212. with distilled water ILab 300 Plus Service Manual Rev 03 January 2004 Page 21 Chapter 08 Host Communication CHAPTER 08 HOST COMMUNICATION INDEX 8 1 COMMUNICATION WITH THE HOST COMPUTER mee 2 8 1 1 COMMUNICATION PARAMETERS e erede inae epa uo aa 2 8 2 PROTOCOL SPECIFICATIONS eel o ee 3 8 3 HEADER RECORD n e i ode e ete a aA R id 4 8 4 PATIENT RECORD P h aii tinet alte He Hei Mite e reri 5 8 3 LES ORDER RECORD UO 7 8 0 RESULTS RECORD R dte aget tete 10 8 7 MESSAGE TERMINATOR RECORD L eese nennen nennen 12 8 8 REQUEST INFORMATION RECORD 13 ILab 300 Plus Service Manual Rev 03 January 2004 Page 1 Chapter 08 Host Communication 8 1 COMMUNICATION WITH THE HOST COMPUTER The JLab 300 Plus can be connected to a host computer for the purpose of facilitating results print out and patient management In order to enable communication between the Lab 300 Plus and the host computer select the Host Link field under Options in the Parameters menu To activate communication between the 300 Plus and the host computer select Host Tx please see the software description in Chapter 03 of the User s Manual 8 1 1 COMMUNICATION PARAMETERS The Lab 300 Plus is linked to the managing computer using an R
213. y 2004 Page 2 Chapter 01 INTRODUCTION 1 3 3 Mechanical risks Several precautionary measures should be taken when operating the analyzer avoid wearing very loose clothing or jewelry that could become tangled in the instrument s moving parts e g the sample probe whenever possible operate the instrument with the main cover panel lowered WARNING Never attempt to service or substitute any part s of the analyzer when the instrument is turned on Any and all technical repairs or servicing must be performed by specialized personnel only 1 4 TECHNICAL OPERATING FEATURES Fully automatic random access continuous loading DESCRIPTION benchtop analyzer for clinical chemistry and immunoturbidimetric assays ASSAY TYPE End Point Initial Rate Kinetic Bichromatic Differential TEST ENTRY MODE Selective Batch Profiles STAT THROUGHPUT 200 test per hour without ISE module WORKING TEMPERATURE 6 37 C 4 removable racks two racks cooled by Peltier cells ON LINE REAGENTS and two racks at room temperature e 3342 reagent positions of 40 ml or 7 ml each 15 positions at room temperature and 20 cooled e 14 positions for Standards and Controls 5 for continuous loading of samples split in SAMPLE LOADING F e 4racks for 16 positions each for 14 positions STAT Continuous loading Positive barcode reader ILab 300 Plus Service Manual Rev 02 January
214. y 2004 Page 37 Chapter 06 SETTINGS AND ADJUSTMENTS CHAPTER 06 SETTINGS AND ADJUSTMENTS INDEX 6 SETTINGS AND ADIUS EMEIN ES 4 6 1 SAMPEINGARM ct IR duae a putat tu s datar alu dus 4 6 1 1 ALIGNMENT AND ADIUSTMEN ES t trece td ime a oer edet RAR AS 4 6 1 2 SUBSTITUTION OF THE SAMPLING 6 6 1 3 SUBSTITUTION OF THE OPTIC SENSORS dei ped ao Eoo 7 6 1 3 1 SUBSIIEUIDONOPFTHEOSs7OPPIC SSENSODR a d iir RE EPUM 7 6 1 3 2 SUBSTITUTION OF THE 056 AND OS5 SENSORS eee 9 6 1 3 2a SUBSTITUTION OF THE OS6 5 5 10 6 1 3 2b SUBSTITUTION OF THE 055 OPT COUPLER eene 11 6 14 SAMPLING ARM MOTORS 56 RE ade raa 12 6 1 4 1 SUBSTITUTION OF THE M7 MOTOR bp n ra uot inet sende 13 6 1 4 2 SUBSTITUTION OF THE M6 MOTOR jit o eiae a Pt ecu 17 6 14 3 SUBSTITUTION OF LHE MS MOTOR eth m ee Hr tr terres 19 6 1 5 PRE HEATBROYNDEEVEE SENSOR 2l 6 1 5 1 SUBSTITUTION OF THE PRE HEATER AND LEVEL SENSOR ASSEMBLY 21 6 1 5 2 LEVEL SENSOR FUNCTIONING CHECK 25 6 1 6 DIEVTER MODU TB ve eet oe eee eee ohne 27 6 1 6 1 SUBSTITUTION OF THE DILUTER MODUDLE eene enne 27 6 1 6 2 SUBSTITUTION OF THE DILUTER
215. y necessary also the internal arm can be adjusted loosen only one of its fastening screws Fig 1 Pre heater Guide Support Internal Arm Belt 6M 203 Arm Horizontal Movement Pn 23135000500 Protective Cover Reagents Protective Cover Samples Protective Cover ILab 300 Plus Service Manual Rev 04 January 2004 Page 4 Chapter 06 SETTINGS AND ADJUSTMENTS 5 Tighten the External Arm fastening screws and if necessary those of the Internal Arm centering the probe with respect to the wash well 6 Perform a complete Arm reset in order to ascertain correct centering of the probe on the wash well If the centering is not exact repeat steps 4 and 5 7 After having mechanically centered the sampling probe on the wash well adjust all the other positions by using the computer s numeric keyboard as follows N B make sure that the distance between the top edge of the wash well and the tip of the probe is 2 0 0 5 mm Use the following keys to make the necessary adjustments e move arm horizontally e lt Next gt to move forward one position lt Prev gt to move back one position e 9 to move upward 3 to move downward 8 Select Sample from Setting of and then press the Go key The arm will automatically move itself to position 1 of the Samples rack Adjust the positioning by using the keys indicated for centering the probe with respect to
216. y the following items e Temperature probe e Calibrator Resistor A 10 KO e Calibrator Resistor 5 76 KO 4 Procedure description With a thermostatic bath heat 250 500 mL of distilled water up to 37 37 5 C see page 3 if a thermostatic should be not not available CHECK WHETHER THE INTEGRATED CHIP TL O71xxx IS INSTALLED ON THE CONTROL PANEL BD POS U2 see fig 1 AND REPLACE IT WITH THE INTEGRATED CHIP LMC 7101 A or or TLV 2461 BEFORE APPLYING THE FOLLOWING PROCEDURE ILab 300 Plus Service Manual Rev 04 January 2004 Page 60 Chapter 06 SETTINGS AND ADJUSTMENTS e Turn on the system and wait in order to allow the instrument working temperature settlement The warm up may vary from 30 minutes at about 21 C room temperature up to 100 minutes at about 18 C room temperature e During warm up time remove the protection cover of the Control Panel Board Front Side Light Indicators See fig 1 e During warm up time launch the Diagnostic program and then select the Temperature Folder in the Diagnostic Program e During warm up time select Calibration Sensor and carry out the three steps by following the indications showed on the screen e Replace the calibration resistor with the temperature probe Note 1 Now the temperature probe and the service probe function can be used as a thermometer Then route the temperature probe tip through the small door fo
Download Pdf Manuals
Related Search
Related Contents
TWO CYLINDER SERVICE MANUAL L`économie sociale et solidaire en Amérique latine depuis Rio+20 Crown Audio 133472-1A Stereo Amplifier User Manual Troy-Bilt TB32 EC User's Manual Manuel d`instructions IBM PowerPC 401 Evaluation Board Kit User`s Manual Samsung Samsung Galaxy Pocket Neo Duos Инструкция по использованию Fisher VMC-8614F Computer Monitor User Manual Renseignements de sécurité sur la scie circulaire `=`= BlackBerry Copyright © All rights reserved.
Failed to retrieve file