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1. Viebke C Flynn C Siemensma A D Gum arabic establishes prebiotic functionality in healthy human volunteers in a dose dependent manner Br J Nutr 2008 100 1269 1275 e Chaudhri O B Salem V Gastrointestinal satiety signals Annu Rev Physiol 2008 70 239 255 e Cinotti S Gugllelmini C Boari A The effect of psyllium on some haemotologic and biochemical variables in the plasma of horses during an endurance ride preliminary results Pferdeheilkunde 1997 13 23 6 e Costabile A Kolida S Klinder A Gietl E Bauerlein M Frohburg C Landschutze V Gibson G R A double blind placebo controlled cross over study to establish the bifidogenic effect of a very long chain inulin extracted from globe artichoke Cynara scolymus in healthy subjects Br J Nutr 2010 104 1007 1017 e Cummings J H The Effect of Dietary Fiber on Fecal Weight and Composition In CRC Handbook of Dietary Fiber in Human Nutrition Spiller G A Ed CRC Press Boca Raton FL USA 1993 pp 263 333 e Cummings J H Macfarlane G T The control and consequences of bacterial fermentation in the human colon J Appl Bacteriol 1991 70 443 459 e de Latt MA McGowan CM Sillence MN Pollitt CC Equine laminitis induced by 48 h hyperinsulinemia in Standardbred horses Equine Vet J 2010 42 129 35 Dyer J Merediz F Salmon K Proudman CJ Edwards GB Shirazi Beechey SP Molecular characterisation of carbohy drate digestion and absorptio
2. blood hormone concentrations and plasma lipid concentrations in obese horses with insulin resistance J Am Vet Med Assoc 2006 228 1383 90 e Freestone JF Shoemaker K Bessin R Wolfsheimer JK Insulin and glucose response following oral glucose adminis tration in wellconditioned ponies Equine Vet J 1992 11 13 7 Galvin N amp col Right Dorsal Colitis in the Horse Irish Veterinary Journal 2004 57 8 e Geor R J Metabolic predispositions to laminitis in horses and ponies obesity insulin resistance and metabolic syndromes J Equine Vet Sci 2008 28 753 9 e Geor R J Thatcher C D Pleasant R S Elvinger F Gay L Were S R Prevalence of hyperinsulinemia in mature horses relationship to adiposity Abstract J Vet Intern Med 2007 21 601 e Gibson G R Scott K P Rastall R A Tuohy K M Hotchkiss A Dubert Ferrandon A Gareau M Murphy E F Saulnier D Loh G et al Dietary prebiotics Current status and new definition Food Sci Technol Bull Funct Foods 2010 7 1 19 e Gibson G R Probert H M van Loo J Rastall R A Roberfroid M B Dietary modulation of the human colonic microbiota Updating the concept of prebiotics Nutr Res Rev 2004 17 259 275 e Gibson G R Roberfroid M B Dietary modulation of the human colonic microbiota Introducing the concept of prebiotics J Nutr 1995 125 1401 1412 e Gordon J l Ley R E Wilson R Mardis E Xu J Fraser C M Relman D A E
3. e Meyer RH Kiengle S Wilke S Kleffken D Investigations of preileal digestion of oats corn and barley starch in relation to grain processing Proceedings 16th Equine Nutrition and Physiology Symposium Gainsville FL 1993 13 92 7 e Moreaux S J J Nichols J L Bowman J G P Hatfield P G Psyllium Lowers Blood Glucose and Insulin Concentra tions in Horses J Eq Vet Sci 2011 31 160 165 e Musso G Gambino R Cassader M Gut microbiota as a regulator of energy homeostasis and ectopic fat deposition Mechanisms and implications for metabolic disorders Curr Opin Lipidol 2010 21 76 83 e Nazare J A Sauvinet V Normand S Guerin Deremaux L Gabert L Desige M Wils D Laville M Impact of a resistant dextrin with a prolonged oxidation pattern on day long ghrelin profile J Am Coll Nutr 2011 30 63 72 e Nourian AR Asplin KE McGowan CM Sillence MN Pollitt CC Equine laminitis ultrastructural lesions detected in ponies following hyperinsulinemia Equine Vet J 2009 41 671 7 e Pagan JD Harris PA Kennedy MA Davidson N Hoekstra KE Feed type and intake affects glycemic response in thoroughbred horses In Proceedings 16th Equine Nutrition and Physiology Symposium Raleigh NC 1999 149 50 e Pasman W Wils D Saniez M H Kardinaal A F Long term gastrointestinal tolerance of NUTRIOSE FB in healthy men Eur J Clin Nutr 2006 60 1024 1034 e Ramnani P Gaudier E Bingham M van Bruggen P T
4. A P Sahuagun A M et al Effects of ispaghula husk and guar gum on post prandial glucose and insulin concentrations in healthy subjects Euro J Clin Nutr 2001 55 235 43 VetNova Tel f 34 918 440 273 vetnova vetnova net www vetnova net Sand Control Suplemento de Psyllium en gr nulos de alta palatabilidad para el control del c lico de arena el estre imiento cr nico y el sindrome metab lico equino e Sierra M Gracia J J Fern ndez N Diez M J Calle A P Farmafibra Group Therapeutic effects of psyllium in type 2 diabetic patients Euro J Clin Nutr 2002 56 830 42 Spahn J M Lyon J M Altman J M Blum Kemelor D M Essery E V Fungwe T V Macneil P C McGrane M M Obbagy J E Wong V P The systematic review methodology used to support the 2010 Dietary Guidelines Advisory Committee J Am Diet Assoc 2011 111 520 523 e Van Loo J Coussement P de Leenheer L Hoebregs H Smits G On the presence of inulin and oligofructose as natural ingredients in the western diet Crit Rev Food Sci Nutr 1995 35 525 552 e VetNova VCC Sand Control Published Research Abstracts Compilation 2013 Si le interesa alguno de los articulos listados por favor no dude en solicitarlos a traves de los siguientes contactos vetnova vetnova net 918 440 273 o su Delegad T cnico Comercial VetNova VetNova Tel f 34 918 440 273 vetnova vetnova net www vetnova net
5. Dietary fiber magnesium and glycemic load alter risk of type 2 diabetes in a multiethnic cohort in Hawaii J Nutr 2010 140 68 74 e Howarth N C Saltzman E Roberts S B Dietary fiber and weight regulation Nutr Rev 2001 59 129 139 e Howlett J J Betteridge V A Champ M Craig S A S Meheust A Jones J M The definition of dietary fiber Discussions at the Ninth Vahouny Fiber Symposium Building scientific agreement Food Nutr Res 2010 54 doi 10 3402 fnrv5405750 e Jenkins DJ Wolever TM Ocana AM Vuksan V Cunnane SC Jenkins M et al Metabolic effects of reducing rate of glucose ingestion by single bolus versus continuous sipping Diabetes 1990 39 775 81 e Jones J M Dietary Fibre s Co Passengers Is It the Fibre or the Co Passengers In Dietary Fiber New Frontiers for Food and Health van der Kamp J W Jones J Mccleary B Topping D J Eds Wageningen Academic Publishers Wageningen The Netherlands 2010 pp 365 378 e Kohnke J Feeding Old Horses AVA VetNova Tel f 34 918 440 273 vetnova vetnova net www vetnova net VETERINARY CLINICAL CARE Suplemento de Psyllium en gr nulos de alta palatabilidad para el control del 1 c lico de arena el estre imiento cr nico y el s ndrome metab lico equino J F IC A TECN ICA e Kellon E We Like Pure Psyllium Horse Journal 2011 e Leach J D Sobolik K D High dietary intake of prebiotic inulin type fructans in the prehistoric Chihauh
6. VETERINARY CLINICAL CARE Suplemento de Psyllium en gr nulos de alta palatabilidad para el control del HE i c lico de arena el estre imiento cr nico y el s ndrome metab lico equino J F ICH A TECN ICA Ingredientes activos por dosis Plantago ovata 21 640 mg Composicion Cuticula de semilla de Psyllium Plantago ovata cido propi nico saborizante de manzana aceite mineral melaza deshidratada Componentes anal ticos Prote na bruta 12 3 aceites y grasas brutas 6 95 fibra bruta 5 4 ceniza bruta 6 2 humedad 10 0 pS calcio 0 45 f sforo 0 29 sodio 0 08 C ara cteristi cas Propiedades El Psyllium proviene de la cut cula de la semilla de Plantago ovata una planta particular mente rica en fibra y muc lagos que le confieren sus propiedades digestivas Contiene un 85 de fibra soluble mucho m s que otras semillas com nmente utilizadas en la alimentaci n de los caballos como Tratamiento y prevenci n de los el salvado de avena y trigo que contienen un 15 y 10 respectivamente Esta fibra tiene una estructura c licos de arena de polisac ridos nica que le hace resistente a la digesti n y absorci n en el est mago e intestino delgado y a la fermentaci n bacteriana en el colon Una vez en el aparato digestivo el Psyllium absorbe gran cantidad de agua y forma una masa gelatinosa que hidrata y reduce la viscosidad de las heces y aumenta su volumen Manejo del estre imiento cr nico Meca
7. iminar el contenido residual de arena tras una operaci n de c lico por arena e Laxante manejo del estre imiento cr nico o en situaciones en las que una defecaci n facil con heces blandas es deseable por ejemplo en casos de defecaci n dolorosa tras una cirug a rectal o anal laceraciones fistulas recto vaginales postparto hemorroides desgarros o heridas etc e Reducci n de los niveles de glucosa e insulina en sangre para prevenir el sindrome metab lico equino caracterizado por tres signos principales obesidad resistencia a la insulina y laminitis de origen endocrino e Prevenci n de la hiperlipemia en caballos obesos y en especial yeguas gestantes o en lactaci n con sobrepeso ponis y burros cuando se dan a la vez una reducci n de ingesta de alimento y una situaci n de estr s Especies de destino Equidos VetNova Tel f 34 918 440 273 vetnova vetnova net www vetnova net VETERINARY CLINICAL CARE Suplemento de Psyllium en gr nulos de alta palatabilidad para el control del HE a colico de arena el estrenimiento cronico y el sindrome metabolico equino A F ICHA TECN ICA Modo de empleo e Prevenci n del c lico de arena en animales predispuestos o con historial de ingesti n de arena o como seguimiento post quir rgico de un c lico de arena para eliminar la arena restante 30 g por cada 100 kg de peso al d a durante 5 d as seguidos cada mes e Expulsi n de grandes cantidades de arena previo diag
8. n stico 90 g por cada 100 kg de peso al d a durante 3 5 d as e Lubricante laxante intestinal 15 g por cada 100 kg de peso al d a hasta la desaparici n del estre imiento La medida incluida rasa equivale a 30 gramos Los animales deber n tener acceso permanente al agua La c scara de Plantago ovata act a dentro de las 12 a 24 horas post administraci n a veces el efecto m ximo no se alcanza antes de 2 0 3 d as Presentaci n 1 5 kg 50 dosis 2 meses de suministro Bibliograf a e Asplin KE Sillence MN Pollitt CC McGowan CM Induction of laminitis by prolonged hyperinsulinemia in clinically normal ponies Vet J 2007 174 530 5 e Bach Knudsen K E The nutritional significance of dietary fibre analysis Anim Feed Sci Technol 2001 90 3 20 Biorklund M Rees A van Mensink R P Onning G Changes in serum lipids and postprandial glucose and insulin concentrations after consumption of beverages with beta glucans from oats or barley A randomized dose controlled trial Eur J Clin Nutr 2005 59 1272 1281 e Bonnema A L Kohlberg L W Thomas W Slavin J L Gastrointestinal tolerance to chicory inulin products J Am Diet Assoc 2010 110 865 868 e Brownawell A M Caers W Gibson G R Kendall C W C Lewis K D Ringel Y Slavin J L Prebiotics and the health benefits of fiber Current regulatory status future research and goals J Nutr 2012 142 1 13 e Calame W Weseler A R
9. n in equine small intestine Equine Vet J 2002 34 349 58 Eli M Cattivelli D Soldi S Bonatti M Morelli L Evaluation of prebiotic potential of refined psyllium Plantago ovata fiber in healthy women J Clin Gastroenterol 2008 42 174 S176 Ellis AD Hill J Digestive physiology of the horse In Nutritional Physiology of the Horse Nottingham UK Nottingham University Press 2005 p 34 7 e EMEA Assessment report on Plantago ovata Forssk seminis tegumentum EMEA Report 2013 Fischer M Yu N Gray RG Ralph J Anderson L Marlett JA The gelforming polysaccharide of psyllium husk Plantago ovata Forsk Carbohydr Res 2004 339 2009 17 VetNova Tel f 34 918 440 273 vetnova vetnova net www vetnova net VETERINARY CLINICAL CARE Suplemento de Psyllium en gr nulos de alta palatabilidad para el control del 1 c lico de arena el estre imiento cr nico y el s ndrome metab lico equino J F IC A TECN ICA Frank N Geor RJ Bailey SR Durham AG Johnson PG Equine metabolic syndrome ACVIM consensus statement J Vet Int Med 2010 24 467 75 e Frank N Equine metabolic syndrome J Equine Vet Sci 2009 29 259 67 e Frank N Endocrinopathic laminitis obesity associated laminitis and pasture associated laminitis Proceeding of the 54th Annual Convention of the American Association of Equine Practitioners San Diego CA 2008 341 6 e Frank N Elliot SB Brandt LE Keisler DH Physical characteristics
10. nismo de acci n Efecto laxante y lubricante e La viscosidad de las heces se ve muy afectada por la cantidad de agua en el contenido fecal La alta capacidad de retenci n de agua de Plantago ovata hasta 40 veces su peso reduce en gran medida la viscosidad de las heces En consecuencia hay una menor resistencia que resulta en un tr nsito m s r pido o un tiempo de transito m s corto hae F El Psyllium tambi n aumenta la masa fecal hasta 3 7 g por cada gramo consumido y por tanto la Control de la laminitis S ndrome tensi n de la pared intestinal estimulando el peristaltismo y por consiguiente reduciendo la constipa Metab lico Equino ci n Los productos de degradaci n de la fibra diet tica como resultado de la acci n bacteriana en el colon tambi n pueden contribuir al efecto laxante Brunton 1990 Kay et al 1978 e Al mismo tiempo el mucilago forma una capa lubricante alrededor de la pared del intestino que facilita el tr nsito del contenido intestinal sin irritar su mucosa El Psyllium reduce la resistencia a la insulina disminuyendo considerablemente la movilizaci n masiva de cidos grasos reesterificados en el h gado a triglic ridos Este efecto est asociado a las fibras de la fracci n soluble Alta palatabilidad gr nulos con sabor a manzana y melaza Indicaciones Eliminaci n de arena del colon ventral prevenci n del c lico de arena en animales predispuestos y para No contiene sustancias dopantes el
11. uan desert Br J Nutr 2010 103 1158 1561 e Lefranc Millot C Gruerin Deremaux L Wils D Neut C Miller L E Saniez Degrave M H Impact of a resistant dextrin on intestinal ecology How altering the digestive ecosystem with NUTRIOSE a soluble fiber with prebiotic properties may be beneficial for health J Int Med Res 2012 40 211 224 e Ley R E Turnbaugh P J Klein S Gordon J Microbial ecology Human gut microbes associated with obesity Nature 2006 444 1027 1031 e Lied G A Lillestol K Lind R Valeur J Morken M H Vaali K Gregersen K Florvaag E Tangen T Berstad A Perceived food hypersensitivity A review of 10 years of interdisciplinary research at a reference center Scan J Gastroenterol 2011 40 1169 1178 e Livesey G The energy values of dietary fibre and sugar alcohols for man Nutr Res Rev 1992 5 61 84 e Lupton J R Microbial degradation products influence colon cancer risk The butyrate controversy J Nutr 2004 134 479 482 e McGowan C The role of insulin in endocrinopathic laminits J Equine Vet Sci 2008 28 603 7 e Marlett JA et Col A Poorly Fermented Gel from Psyllium Seed Husk Increases Excreta Moisture and Bile Acid Excretion in Rats J Nutr 2002 2638 43 e Mathern J R Raatz S K Thomas W Slavin J L Effect of fennugreek fiber on satiety blood glucose and insulin response and energy intake in obese subjects Phytother Res 2009 23 1543 1548
12. uohy K M Gibson G R Prebiotic effect of fruit and vegetable shots containing Jerusalem artichoke inulin A human intervention study Br J Nutr 2010 104 233 240 e Roberfroid M Gobson G R Hoyles L McCartney A L Rastall R Rowland Wolvers D Watzl B Szajewska H Stahl B et al Prebiotic effects Metabolic and health benefits Br J Nutr 2011 104 S1 S63 Sillence MN Pollitt CC McGowan CM What causes equine laminitis The role of impaired glucose uptake Kingston ACT Australia Rural Industries Research and Development Corporation 2007 1 23 Publication no 07 158 e Slavin J Fiber and Prebiotics Mechanisms and Health Benefits Nutrients 2013 5 1417 1435 e Slavin J Feirtag J Chicory inulin does not increase stool weight or speed up intestinal transit time in healthy male subjects Food Funct 2011 2 72 77 e Slavin J L Savarino V Parades Diaz A Fotopoulos G A review of the role of soluble fiber in health with specific reference to wheat dextrin J Int Med Res 2009 37 1 17 e Slavin J L Position of the American Dietetic Association Health implications of dietary fiber J Am Diet Assoc 2008 108 1716 1731 e Slavin J Green H Dietary fibre and satiety Nutr Bull 2007 32 32 42 e Slavin J L Dietary fiber Classification chemical analyses and food sources J Am Diet Assoc 1987 87 1164 1171 e Sierra M Gracia J J Fern ndez N Diez M J Calle
13. xtending our view of self The Human Gut Microbiome Initiative HGMI Available online http www genome gov Pages Research Sequencing SeqProposals HGMISeq paf accessed on 8 October 2011 e Gordon ME Jerina ML Raub RH Davison KE Young JK The effects of feed form on consumption time and glucose and insulin response to a concentrate meal in equine J Equine Vet Sci 2008 28 289 94 e Guerin Deremaux L Pochat M Reifer C Wils D Cho S Miller L E The soluble fiber Nutriose induces a dose dependent beneficial impact on satiety over time in humans Nutr Res 2011 31 665 672 e Grabitske H A Slavin J L Gastrointestinal effects of low digestible carbohydrates Crit Rev Food Sci Nutr 2009 49 327 360 e Grabitske H A Slavin J L Low digestible carbohydrates in practice J Am Diet Assoc 2008 108 1677 1681 e Hengst C Ptok S Roessler A Fechner A Jahreis G Effects of polydextrose supplementation on different faecal parameters in healthy volunteers Int J Food Sci Nutr 2009 60 96 105 e Henneke DR Potter GD Kreider JL Body condition during pregnancy and lactation and reproductive efficiency of mares Theriogenology 1984 21 897 909 e Hoffman RM Carbohydrate metabolism in horses In Ralston SL Hintz HF editors Recent Advances in Equine Nutrition Ithaca NY International Veterinary Information Service 2001 Hopping B N Erber E Grandinetti A Park S Y Kolonel L N Maskarinec G
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