添付文書 - DSファーマバイオメディカル株式会社
Contents
1. 2 3 3 1 1 000 ppm 1 2 1 121 C 20 22. 1 2 8 C 2 15 1 96 40 THE BONE 3 3 33 40 1989 2 94 102 1995 3 Colwell A et al Effect of diet on deoxypyridinoline excretion In Christiansen C Overgaard K eds Osteoporosis 1990 Osteopress Copenhagen 590 591 1990 4 Uebelhart D et al Urinary excretion of pyridinium crosslinks Anew marker of bone resorption in metabolic bone disease Bone Mineral 8 87 96 1990 5 Robins SP et al Evaluation of urinary hydroxyDyridinium crosslinks measurement as resorption markers in metabolic bone disease Eur J Clin Invest 21 310 315 1991 6 Ohishi T et al Urinary bone resorption markers in patients with metabolic bone disorders Bone 15 15 20 1994 7 Uebelhart D et al
3. Dpd D pNPP Dpd Dpd Dpd Dpd 2014 3 4 _ 2009 1 3 20900AMY00081000 GD pb 6 T Dpd 1T Pp Dpd P lt DpoD Dpd lt amp NPP gt gt 1
4. 9 4 10 7 NM 20 28 C 1 8x1 4 6 8 12 8 16 24 40 Dpd 1 1 2 2 1 1 DN mL 100 150 200 300 0 1 10
5. 9 0 e a 4 30 i 10 8 _ si _ EE 11 3 94 15 27 32 8 11 263 351 1 Dpd 0 T T T 3 MN OO MM OM 36 29 40 19 32 5 3 9 3 25 lt e 20 15 1 10 1 2 TE 8 167 113 56 14 2 Dpd p 0 05 p lt 0 01 7 5 4 a 9 8 1 2 5 2 0 0 0 1 3 6 9 3 Dpd
6. 10 50L 450L 1 50rL Dpd Dpd 3 100L Dpd 4 4 C 2 5 30 60 1 20 28 C 2
7. 1 2 5 3 4 2 8 C 1 20 C 5 OS 3 Fo 0 500mg dL 0 500mg dL 0 5g dL 0 2mg dL 0 25mg dL 1 2 300nmol L 3 Dpd 0nmolL
8. DPD EIA Dpd Dpd Dpd 1 1 2 3 58 7 66 3
9. 20 28 C 24 4 6 2 8 C 2 Dpd 7mL Dpd 2 2 8 C 3 1 60 20 28 C 1 3 4 7mL 50 500gL 5 6 Fo 5 100 300L 6 405nm Dpd Dpd Dpd Dpd
10. 90 1 Dpd 2 3 Dpd DD Dpd 9 5 6 7
11. 6 1 2 20 28 C 300L 3 1 4 2 3 2 3 5 co 2 1 5 2 8 C 5 20 28 C 5 150zL 8 20 28 C 1
12. B1401 MB 2 HPLC 200 y 1 9 0 50x r 0 93 n 56 100 nmol L 0 0 100 200 HPLC nmoL 3 T 300 400 1 1 2 0 05 0 5molL 2 1
13. 0 8 4 Dpd Certificate of Analysis 5 6 Dpd Dpd 8
14. 9 100L 0 405nm 15 2 600 650nm Dpd Dpd Dpd Dpd 10 50L Dpd 100L 4 C 2 300gLX 3 150L 20 28 C 60 100uL 15
15. 9 2 12 10 10 3 Dpd 0 74 p lt 0 01 n 13 Dpd Dpd 0nmol L 1 0 Dpd 300nmolL 0 3 Dpd 0nmolL 3nmol L 3nmolL 0nmolL 2 20 3 6 15 4 3 300nmol L
16. 405nm 405nm Dpd nmol L 1 2 nmol L Dpd Cr mmol L Cr nmolmmol Cr mg dLx 0 088 mmol L Cr 3 263 25 72 353 20 70 2 1 5 4nmol mmol Cr 2 8 7 6nmol mmol Cr 4 Dpd
17. 1 1 8 12 Dpd Dpd 0nmolL 1 0 2 0 2 Dpd 1 0 3 10 30 100 300nmol L 0 3mL 3 Dpd 1 0 3mL 4 Dpd 3 Dpd 9 6ng 1 5 1 55mL 6 3 20mg p 0 3mg 1 7 3 10mL 8 1 55mL 9 1 15mL Dpd EIA Dpd Dpd Dpd AP Dpd
18. 337 5941 FAX 06 6337 6020 DS 2 1 43 564 0063 4 B1401 MB
19. B1401 MB 2 DPD 1 3 4 NN oo NCAA 5 2 9 96
20. Effect of menopause and hormone replace ment therapy on urinary excretion of pyridinium crosslinks J Clin Endocrinol Metab 72 367 373 1991 8 Robins SP et al Direct enzyme linked immunoassay for urimary deoxyDyridinoline as a specific marker for measuring bone resorption J Bone Miner Res 9 1643 1649 1994 9 44 9 125 128 1996 44 9 1011 1023 1996 EIA 44 8 873 883 1996 2 Black D et al Quantitative analysis of Pyridinium Cross links of collagen in urine using ion paired reversed phase high performance liquid chromatography Anal Biochem 169 197 203 1988 DS 1 33 94 564 0053 06 6
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