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1. 3 N NH NH CI CI N CI CI
2. 1 1 2 4 8 3 1 5kg 4 3 SC 5 20 2 1
3. 1 E38 2 202 3 OB ES 250mL 4L 1
4. 24 0 25ug mL 1 2 Dermcare 3 4 AALASEB 0 1 Wc 2XIOIne gluconate 100mL 2 0g 2 0g a assezja
5. 2 SE 3 0 4 2 5 4 2 1 2 3 4 5 6
6. ROSS IS 2 Ee 3 1 2 3 879549 4 5 P450
7. IO 8 0 E 10 9 CC
8. 2 ss20 50652 lm af ml Negre et al 2008 Evidence based Veterinary Dermatology a Systematic Review of Interventions for Malassezia Dermatitis in Dogs Veterinary Dermatolology 20 1 12 Ll Lr al sT wm 100mL 2 0g
9. 0 6 7 0 8 1 2 1 2 3 4
10. 1 2 MIC MIC il Vi im my ewiwW Malassezia Malassezia pachydermatis 1 Micrococcus Micrococcus flavus 0 5 Malassezia furfur 0 1 Micrococcus lutea 0 5 Candida Candida sp 10 Staphylococcus Staphylococcus aureus 1 6 Trichosporon Trichosporum cutaneum 1 Staphylococcus a 7 Geotrichum Geotrichum candidum 100 pseudintermedius Microsporum Microsporum canis 1 Staphylococcus epidermidis 1 8 Microsporum audouini 1 otreptococcus Streptococcus faecalis 38 Microsporum gypseum 10 Streptococcus mutans 2 5 Trichophyton Trichophyton 91 streptococcus pneumoniae 11 mentagrophytes Streptococcus pyogenes 3 Trichophyton sp 1 10 Streptococcus sanguls 9 Epidermophyton Epidermophyton floccosum _0 1 Bacillus Bacillus subtilis 1 Corynebacterium Corynebacterium SO 1 6 Propionibacterium Propionibacterium acne 8 Escherichia Escherichia coli 4 1 Van Cutsem J M et al 1972 Miconazole a Broad Spectrum Antimycotic Pseudomonas Pseudomonas aeruginosa 20 Agent with Antib
11. 2 4 9 WBC a Fa 2 e14 0 5mL 2X3cm 4 60 24 48 72 ae 5ca e 0 33 4 3
12. 45 s 8 45 45 MFC MBC MIC IA8 MFC MBC MFC M pachydermatis 3 3ug mL 2 0ug mL 20 0g L 1 444 3 3 S pseudintermedius 20 0 g mL 6 7 g mL 20 0g L 444ug mL 0 02g 45 444 20 2 2 2 p lt 0 01 2 2 6 1 2006 2 Davies G E et al 1954 1 6 DI 4 CHLOROPHENYLDIGUANIDOHEXANECHIBITANE Laboratory investigation of a new a
13. 84 3 1 2 2 LDso 2500mgo kg 1000mg kg 2 1 1 2000mg GHS 5 4 _ e 3
14. 20 10mL 2 0g 10 1 1 3 2 1 SU DAT 1 5 3Kg UI 3 5kg on 5 10kg 052 Sm 10 15kg OE 15 20kg 30 4Om 20 30Kg 40 50 30 40kg 0 60 40 50kg 040 1 1
15. 47 8 51 5 51 8 32 1 1 AALASEB 22 28 6 35 45 5 17 22 1 3 3 9 77 74 0 4 11 4 3 8 6 15 42 9 13 37 1 35 20 0 p 0 001 1 X100 1 Mann Whitney U G Wilcoxon 85 70 85 40 70 40 1 pS0 0019 76 3 74 0
16. pS0 001 1 1 p 0 009 p 0 001 p 0 0420 p50 001 p 0 001 9 84 3 1 2 M pachydermatis S pseudintermedius
17. 7 1 0 6 VNS Verbal Numerical Scale 1g 10mg 9 76 3 p 0 001 322 es 26 9 23 8 47 6 psS0 001 p 0 001 pS0 001 VNS VNS 1 100 9 73 69 6 74 1 72 7
18. es on Li gt KIRIKAN Data 2w v E__ EL 2w v Dermcare Vet Pty Ltd 1996 9 2 76 3 2S
19. acterial Activity 17 392 404 Pseudomonas fluorescens 4 2 DENTON G W 1991 Chlorhexidine Disinfection Sterilization and LO Cd 16 274 289 Serratia Serratia marcescens 30 Eidine aluconate
20. ntibacterial agent of high potency British Journal of Pharmacology Vol 9 192 196 3 Lemari J R amp Hogsgood G 1995 Antiseptics and Disinfection in Small Animal Practice The Compendium 17 1342 1347 4 6 Dermcare 5 Bond et al 1995 Comparison of two shampoos for treatment of Malassezia pachydermatis associated seborrheic dermatitis in basset hounds Journal of small Animal Practice 36 99 104 1 000 10 10 126 112 0 1 2 3 4 5 6 7 8 9 10 11 12 13 4 1 2 1 2 1 4 4 10 2 UGC
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