シェアードリサーチ社企業分析レポート - 3D MATRIX [medical technology]
Contents
1.2.
3. 85 85 7777 SR Research Report 201571 7
4. KOL Key Opinion Leader s Shared 6Qesearch la http Wwww sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 7777 SR Research Report 2015 1 7 2014 4 2014 6 12 2014 4
5. 2014 6 4 TDM 621 3 D Matrix Asia Pte Ltd TDM 621 2014 6 3 CE
6. SR Inc SR Inc Shared Researcnh SR Inc
7. 3 amp s Shared 6Qesearch la http Wwww sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 7777 SR Research Report 2015 1 7 14 4 15 4 15 4 pzjgD 1Q 2Q 16 Le le 2Q cie te 48 1 7 51 0 0 10 418 58 4 146 136 145 171 141 281 59 7 50 096 6
8. TDM 621 509 300 om a Fes 7 0
9. Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 7777 SR Research Report 2015 1 7 2013 4 2015 4 TDM 621
10. CE PuraStat 3 D Matrix Asia Pte Ltd 2014 6 7 9 9 PuraStat 2014 6
11. 2015 4 1 160 2015 4 sShared 6Qesearch http Wwww sharedresearchjp Copyright C Shared Research Inc All Rights Reserved w s Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 7777 SR Research Report 2015 1 7 2016 4
12. 3 III 1 1 2 II 3 1 EE
13. MG GCA
14. TDM 621 TDM 621 TDM 621 ee EET mmaommn sm mo mo se mo mw mw a a
15. MIT Shuguang Zhang 2014 11 27 ReproHepato PuraMatrix PuraMatrix iPS ReproHepato W
16. pH TDM 621 a Shared esearch http Www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved Shared csearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 7777 SR Research Report 2015 177
17. G 2014 4 107 1 523 1 525 u 2015 4 TDM 621 10 418 4 483 4 466 3 564 SR 3 MIT
18. 2014 8 21 3 D Matrix Asia Pte Ltd 10096 Ep Shared Research http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 66 85 w 7777 SR Research Report 2015 1 7 20 1009 2014 8 2014 8 28 PuraStat 2014 1 14 PuraStat
19. u a T Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 44 85 w 7777 SR Research Report 201571 7 170
20. ae wa 3 MIT 3 SE 1 2 3 3
21. u u 5263756 U 3 2 sShared 6Qesearch http Wwww sharedresearchjp Copyright C Shared Research Inc All Rights Reserved w 7777 SR Research Report 2015 1 7 3
22. sShared 6Qesearch http Wwww sharedresearchjp Copyright C Shared Research Inc All Rights Reserved amp w 7777 SR Research Report 2015 1 7 TDM 621 K Germany France UK EU taly Spain Switzertand Austria Hong Kong Tf 3 3 New Zealand Singapore CE Indonesia Eo me Talwan Australia Brazil CE 5 arn 9 ST TON 711 6 EU TDM 641 TDN
23. 2010 9 17 Daewoong Pharmaceutical Co LTD PARTNERSHIP AGREEMENT Excelsior Medical Co Ltd LICENSE AGREEMENT CE 2013 5 29 3 D Matrix Asia Pte Ltd PT Teguhsindo Lestaritama CE 2014 7 PuraStat 2015 4
24. MIT Oo sShared 6Qesearch http Wwww sharedresearchjp Copyright C Shared Research Inc All Rights Reserved w 7777 SR Research Report 2015 1 7 5 US 5670483 MIT 1997 9 23 2014 11 29 No oni US 6548630
25. TDM 511 2014 4 2014 2 2014 2 13 3
26. MIT MIT 3 D Matrix Inc 2003 4 MIT Exclusive Patent License Agreement MIT 2004 10 3 D Matrix Inc License and Supply Agreement 3 D Matrix Inc 2007 10 3 D Matrix Inc 3 D Matrix Inc
27. OO HHHHH10H HHHT HH 8 07 HHHHHHHUHHHHHHHHHHHHHH 5 27 BBH For Oppenheiner Global Opportunities Fund 4 53 HHHHHHHH HHHHHHHHHHHHHH 4 35 HHHUHHHHLHHHHHHHHHHHHHHHH 3 75 HHHHHHHHHH 3 22 HH 2 01 OD OO 1 96 CBHK Korea Securities Depository Daishin 1 61 Pershing Div of DL Secs Corp 1 54 HH HHHHHHSRIHHH 2014 4 30 24 6 9 1 2013 4 1 a Shared jesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 81 85 7777 SR Research Report 2015 1 7
28. SR Inc SR Inc SR Tnc SR Tnc SR Tnc 3 31 12
29. 2014 9 9 TDM 641 TDM 641 2014 9 9 PMDA TDM 641 3 amp 7777 SR Research Report 2
30. SR Weaknesses u u MIT MIT 2014
31. 2015 4 10 306 8 474 4 562 3 347 4 548 3 341 3 548 2 241 2016 4 13 497 12 569 6 436 5 780 6 422 5 780 4 011 3 668 2014 4 2 2013 12 6 2014 4 2 2 49 701 701 a T FF sShared esearch http Wwww sharedresearchjp Copyright C Shared Research Inc All Rights Reserved 8 w 7777 SR Research Report 2015 1 7
32. gt TDM G2 1 TOM 621 TDM 621 C s Shar ed Research http Www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w w 7777 SR Research Report 20157177 1987 C
33. TDM 711 TDM 711 3 Ss_ 7777 SR Research Report 2015 1 7 OE TDM 711
34. 2 3 sShared 6Qesearch http Wwww sharedresearchjp Copyright C Shared Research Inc All Rights Reserved amp w 7777 SR Research Report 2015 1 7 2014 1 2014 1 31 3 D Matrix Inc MIT
35. TDM 621 CE TDM 621 3 D Matrix Asia Pte Ltd 2014 6 2014 9 3 2014 7 TDM 621 2014 6
36. 2013 4 2014 4 2013 4 u 2013 4 2015 4 2014 4 4 747 4 495 2 055 1 691 2 049 1 685 1 752 1 441 2015 4 2013 4 2014 4 2014 4 2014 4
37. pH bFGF PDGF PuraMatrix R A D 16 RADA16 87 85 7777 SR Research Report 201571 7 Es
38. MIT sShared 6Qesearch http Wwww sharedresearchjp Copyright C Shared Research Inc All Rights Reserved amp w 7777 SR Research Report 2015 1 7 8901084 Massachusetts Institute of Technology 2010 7713923 7713923
39. 2 2 Shared 6Qesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 88 85 we 7777 SR Research Report 2015 1 7 102 0083 3 2 4 HF 7 03 3511 3440 20
40. 2 58 4 1 3 5 2 54 8 U TDM 621 2014 1 CE CE gt Shared csearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 7777 SR Research Report 2015 1 7 PuraStat
41. 7777 SR Research Report 201571 7 1 u 550 000 2013 7 16 2013 7 18 SMBC 2 2013 7 23 2013 7 25 2 u 80 000 u SMBC 3 80 000 SMBC 2013 8 20 2013 8 23 2013 8 21 2013 8 26 2013 6 2013 6 13
42. 2014 4 3 2014 3 14 2014 4 3 2014 4 3 56 13 1 049 707 1 058 696 1 059 697 U TDM 621 PMDA 2011 5 TDM 621 2014 3 30
43. 3 D Matrix Inc 2004 3 D Matrix Inc 2000 4 MBA
44. MIT 3 D Matrix Inc MIT SR 2014 MIT MIT MIT 2001 5 3 D Matrix Inc
45. TDM 511 TBNP534 1 2
46. 465 2013 4 261 s Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 7777 SR Research Report 2015 1 7 TDM 621 TDM 621 PMDA u TDM 621 PMDA C E 6
47. 3 000 CE CE s a Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 28 85 w s Shared 6Qesearch http Www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 7777 SR Research Report 201571 7 0 USD3 000M 3 000 CE kA1 078 185 94 6 0 KOL 14 000 1cc SR
48. TDM 621 u 2015 4 u 2015 4 u 2015 4 2016 4 u 2014 1 14 CE E U 2015 4 2016 4 TDM 641 2014 12 2016 TDM 631 2015 4 2016 4
49. 2014 8 8 160 1 2014 7 9 1 2 526 sShared 6Qesearch http Www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved amp w 7777 SR Research Report 201571 7 2015 4 15 4 14 4 15 4 107 10 418 10 418 234 9 3 3 0 599 422 1 282 1 704 558 7 16 4 1 024 583 1 326 1 909
50. TDM 641 TDM 641
51. 2 99 0 49 3 3 2013 6 20 19 678 000 2 595 TDM 621 TDM 641 40 2013 10 2017 4 1 460 2013 11 2017 4 160 2013 10 2017 4 340 2013 11 2015 4 800
52. TDM 621 2015 4 TDM 621 4 6 e gt Shared csearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 7777 SR Research Report 201571 7 3 613 122 6 1 704 184 99 1 909 86 2
53. 1 4543 1 4471 2 Shared 6Qesearch http7 www sharedresearchjp Copyright C Shared Research Inc All Rights Reserved 48 85 we 7777 SR Research Report 201571 7 SR
54. 2013 5 20 TDM 621 CE 3 D Matrix Europe SAS TDM 621 CE 2013 5 17 CE EU CE EU EU MDD CE EU TDM 621 CE
55. PMDA FDA u TDM 711 FDA u TDM 641 2014 9 PMDA 2015 3 2 3 s Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 7777 SR Research Report 201571 7 u TDM 511 FDA 510 k
56. u TDM 621 PMDA TDM 621 C E CE FDA 2013 5 3 D Matrix Asia Pte Ltd PT TeguhsindoLestaritama T D M 621
57. 2014 7 9 9 2017 4 2014 11 2013 4 FDA IDE Investigational Device Exemption 2015 4 2015 4 2016 4 2014 1 CE EU EU CE CE s Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w
58. a s Shar ed esear ch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 7777 SR Research Report 2015 1 7 GLP TDM 711 2010 9 FDA IDE 2011 7 IDE 2012 2 Forsyth Institute 1st Pilot Study 2012 6 15 2014 5 FDA 2015 2nd Pilot Study TDM 511
59. u u u
60. TDM 511 3 D Matrix Inc 2014 10 22 FDA 510 k 1 510 K ee gt 1 7777 SR Research Report 201571 7 510 K PMA 90 FDA 510 K FDA 90 FDA
61. CE 45 2013 2013 5 3 D Matrix Asia Pte Ltd 3DMA PT Teguhsindo Lestaritama TDM 621 TDM 621 2014 4 SR TDM 621 u TDM 711 2012 2
62. SR TDM 511 2015 4 s Shared 6Qesearch la http Wwww sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 7777 SR Research Report 2015 1 7 Massachusetts Institute of Technology MIT u MIT MIT
63. 3 D Matrix Inc 2007 10 3 D Matrix Inc 2009 4 s Shared Qiesearch la http Wwww sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 64 85 T Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 7777 SR Research Report 2015 1 7 amp 2014 9 2014 9 10
64. Daewoong Pharmaceutical Co LTD Excelsior Medical Co Ltd PT Teguhsindo Lestaritama TDM 641 1 Shared Wesearch la http Wwww sharedresearch jp Copyright C Shared Research Inc All Rights Reserved PF 7777 SR Research Report 2015 1 7 2 100 MTA
65. 2013 5 15 2013 5 31 1 2 2013 4 2013 4 19 2013 4 3 u 2013 4 32 1 850 1 077 152 1 069 160 1 070 130 2011 5 TDM 621 Shared 6Qesearch http Www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 78 85 w 7777 SR Research Report 2015 1 7 PMDA 2013 4 2014 4
66. 3 D Matrix Asia Pte Ltd 3DMA A STAR Exploit Technologies PTE LTD ETPL A STR Institute of Bioengineering and Nanotechnology IBN Dr Charlotte Hauser ETPL 3DMA 6
67. TDM 621 107 234 7 1 626 57 6 599 51 59 1 024 61 0 1 518 999 1 523 977 1 525 978 u TDM 621 PMDA FDA
68. 4 DDS sShared esearch http Www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved SS 7777 SR Resea
69. 2007 CSBA 2008 JASDAQ 2008 2012 7 a T Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 82 85 w 1 Shared Wesearch la http Wwww sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 7777 SR Research Report 201571 7 2014 4 35 19 38 9 3 4 F 83 85 se 1 Shared Wesearch http Www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 7777 SR Research Report 2015 1 7 IDE Investigational Device Exemption
70. PII II 1 2 3 TDM 621 2009 2015 4 5
71. 3 D Matrix Inc MIT MIT Scientific Founders 2007 10 3 D Matrix Inc 1992 MIT Shuguang Zhang 2001 5 MIT 3 D Matrix Inc 2003 4 3 D Matrix Inc MIT Exclusive Patent License Agreement 2004 5 2004 10 3 DMatrix Inc LICENSE AND SUPPLY AGREEMENT
72. TDM 621 1 Tnformed Consent 2 3 TDM 621
73. siRNA sShared 6Qesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved amp e 7777 SR Research Report 201571 7 CPC Scientific Inc 3 3 TDM 621 2011 5 2009 4 1 8001
74. 1009 609 70 MIT SR CRO
75. 1992 MIT Shuguang Zhang R A D 3 RADA 16 pH ADME 30 DDS
76. SBS DIC KLab TOKAI
77. u 2013 4 2015 4 2014 4 4 495 3 845 1 691 1 091 4 Shared 6Qesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 80 85 we 7777 SR Research Report 2015 177 1 685 1 085 1 441 936 2015 4 2013 4 2014 4 2014 4 2014 4 2015 4 TDM 621
78. 5558104 3 D Matrix Inc 2014 6 17 3 D Matrix Da America Latina Representacao Comercial Ltda 600 000 27 2014 6 13 999 3 D Matrix Europe SAS 1 s Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w
79. TDM 621 TDM 711 TDM 641 TDM 631 TDM 511 TDM 621 RADA16 TDM 621 97 PuraMatrix Corning Incorporated
80. TDM 641 TDM 641 7777 SR Research Report 201571 7 h ou JIIHUTLTLTIT TT se TT TDM 641 TDM 621 RADA16 TDM 621 TDM 641 2014 9 PMDA 2
81. PMDA s Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 7777 SR Research Report 2015 1 7 2014 3 PMDA 2014 4 2015 4 2015 4 2014 4 106 4 178 1 464 1 658 1 475 1 646 1 476 1 491 1 75 57 78 76 2014 4 2014 4
82. 7777 SR Research Report 2015 1 7 q B PuraMatrix B 2014 4 2014 4 1
83. 1 2008 1 30 2008 12 14 6 1 2009 11 30 2010 1 2007 12 160 2008 1 2009 3 TDM 621
84. 10 TDM 621 Daewoong Pharmaceutical Co LTD Excelsior Medical Co Ltd PT Teguhsindo Lestaritama Daewoong Pharmaceutical Co LTD Excelsior Medical Co Ltd 2014 11 2015 4
85. 2014 1 14 CE E U C E C E 2014 1 000 2013 5 3 DMatrix Asia Pte Ltd
86. u 2013 4 1 850 2 491 152 589 160 583 130 529 2011 5 TDM 621 PMDA 2013 4 2014 4 2013 4 2014 4 2013 4
87. Health Sciences Authority 3 D Matrix Asia Pte Ltd CE TDM 621 s Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 7777 SR Research Report 2015 1 7 2014 5 2014 5 30
88. Shared 6Qesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved SS 7777 SR Research Report 2015 1 7 1 2 3 4 PMDA FDA 5 PMDA FDA 6 2 3 7
89. 2015 4 2013 3 2013 3 21 ISO13485 ISO13485 ISO13485 TDM 621 ISO13485 TDM621 2013 2 2013 2 4 TDM 621 FDA IDE s Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w
90. 7777 SR Research Report 2015 1 7 2015 4 CE EU 28 CE TDM 621 2011 5 1 4538
91. 2016 1 344M goxrx 1 600 MNS 1 400 1 200 1 000 900 600 0 CY06 CYO7 Cv08 CYO9 CyY10E CY11E CY12E CY13E CY14E CY15E CY16E 1 SEALANTS HEMOSTATS ONAN 2016 L078M 1200 HH 2010 2016 1 000 800 600 400 200 0 CY10 CY11 CY12 CY13 CY14 CY15 CY16 Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 7777 SR Research Report 2015 177 80 10 113 685 11 526 60 10
92. TDM 711 2012 2 2016 4 TDM 511 2014 10 FDA 510 k CE 510 k s Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 7777 SR Research Report 201571 7
93. 7777 SR Research Report 2015 1 7 TDM 621 US01 2013 2 1 FDA IDE Investigational Device Exemption 1 000 2013 2 1 2013 4
94. siRNA 2015 4 RPN2siRNA A6K RPN2siRNA 3 AGK DDS 4 DDS esearch http Www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 7777 SR Research Report 2015 1 7 2012 3 RNA DDS DDS
95. 2014 1 14 CE EU CE CE 2013 5 3 D Matrix Asia Pte Ltd PT Tegushindo Lestaritama u TDM 711 15
96. 3 PuraMatrix ReproHepato 2014 PuraMatrix ReproHepato PuraMatrix 3 ReproHepato PuraMatrix 2014 11 6 PuraStat
97. 15 FDA u TDM 641 2 3 2014 4 1 4 069 2013 4 2 003 2013 7 23 1 167 1 166 2013 4 2013 6 13 2013 4 Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 7777 SR Research Report 201571 7 32 977 978 2013 4 19 u
98. amp 1 4502 2009 Medmarket Diligence 1 4503 1 3401 CSL 1 4559 AH
99. u TDM 711 2012 2 15 FDA u TDM 641 2014 4 PMDA 2013 7 23 2 1 145 3 328 1 145 3 318 2014 4 1 2013 9 6 2014 4 1 48 341 341 201 3 1
100. 10 PMDA FDA U TDM 711 FDA u TDM 641 2014 9 PMDA 10 30 PMDA u TDM 511 2014 10 FDA 510 k 2015 4 1 2014 9 12 2015 4 1 2015 4 1
101. a T FF sShared esearch http Wwww sharedresearchjp Copyright C Shared Research Inc All Rights Reserved amp w 7777 SR Research Report 201571 7 MIT MIT PuraMatrix PuraMatrix Es a_ A_ gt 2 Ay A ny ay yy AC R A D A R A D A RA D A R AD A CONH A D 1 2 3
102. 5 6 Millennium Research Group 2 000 5 69 3 800 Re ce os hi Proprietary 8 0 Nonproprietary 2 2cx S00 2 8 40 14 6 200 ennlum Research Grog0 US Market for Denlal Biomateriais 0 2010 2010 11 2012 2013 2014 MIT Shared eSsearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 7777 SR Research Report 201571 7 CSL
103. 7777 SR Research Report 2015 1 7 Massachusetts Institute of Technology MIT Shuguang Zhang 2004 5 1992 MIT Shuguang Zhang MIT MIT 2001 5 3 D Matrix Inc 2004 5 2004 10 3 DMatrix Inc LICENSE AND SUPPLY AGREEMENT
104. 2014 7 2014 7 18 TDM 621 3 D Matrix Asia Pte Ltd PT Teguhsindo Lestaritama 2014 7 18 TDM 621 2014 6 3 2 CE Ministry of Health 2015 4 2014 7 14 PuraStat 2014 1 14 PuraStat CE 20
105. 7777 SR Research Report 2015 1 7 2014 6 5
106. 0 48 s Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 7777 SR Research Report 2015 1 7 438 321 471 341 635 341 1 2015 3 TDM 621 U TDM 621 2014 1 CE CE
107. 7777 SR Research Report 2015 1 7 158 2010 4 402 150 2010 4 400 641 2010 4 174 50 TDM 621 122 482 2010 4 65 510 60 534 61 10 4 11 4 12 4 13 4 14 4 544 589 1 758 2 033 2 641 33 39 25 261 789 17 39 718 190 163 594 666 2 501 2 484 3 593 7 6 88 107 103 19 22 30 47 86 537 467 397 327 257 42 38 40 46 56 578 50
108. 5057781 MIT 2012 9 6 PuraMatrix EP 2089047 2012 11 20 BIM 5263756 2013 5 28 US 8647867 2014 5 30 PuraMatri 5497451 2014 4 1 2 PCT SR Shar ed esear ch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 38 85 A Shar ed esearch http Www sharedresearch jp 7777 SR Research Report 2015 177 3 D Matrix Inc MIT AMENDED AND RESTATED EXCLUSIVE PATENT LICENSE AGREEMENT FIRST AMENDMENT SECOND AMENDMENT THIRD AMENDMENT TO AMENDED AND RESTATED EXCLUSIVE PATENT LICENSE
109. Ro 10 205 14 16 DER BSRSREE ES 19 19 PT 20 ER 23 36 37 Be 40 4 41 SW Strengths Weaknesses 44 45 EOID OB 49 TYP 50 KRKV 50 1 57 NSS EE 58 EE EE EER 61 CN 62 Te 62 65 MERHN3NASRERSS3E 30385 81 EN RR NR 82 82 1 83 EE CS 84 84 PCPS2208YPK83EIRBR2RSREH3282D2RRRR 89 1 Shared Yesearch http Www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved T Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 7777 SR Research Report 2015 1 7 u Massachusetts Institute of Technology
110. 7777 SR Research Report 2015 1 7 TDM 621 2010 1 97 2011 4 TDM 621 5 lt 7 2011 5 PMDA TDM 621 2015 4 2 PMDA
111. TDM 621 2015 4 2 TDM 621 PMDA s Shared Qiesearch la http Wwww sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 7777 SR Research Report 201571 7 13 4 14 4 15 4 16 4 32 107 10 418 14 307 18 473 395 599 1 704 1 387 1 725 636 1 024 1 909
112. TDM 641 TDM 711 2012 3 2012 4 TDM 621 3 D Matrix Europe SAS 2012 10 3 D Matrix Asia Pte Ltd 2013 2 TDM 621 FDA IDE 2013 3 ISO13485 2013 5 PT Teguhsindo Lestaritama sShared 6Qesearch http Wwww sharedresearchjp Copyright C Shared Research Inc All Rights Reserved 8 w 7777 SR Research Report 201571 7 TDM 621 2014 1 TDM 621 CE
113. 6 779 4 678 TDM 621 4 000 TDM 621 10 000 TDM 621 3 7 1 387 2015 3 1 704 gt Shared csearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 7777 SR Research Report 201571 7 1 975
114. A6K siRNA Phase 1 2 Phase 1 2011 5 RPN2 A6K DDS siRNA
115. PuraStat 2014 1 14 PuraStat CE 2014 12 27 2014 12 22 Edouard Herriot Hospital Hepato Gastroenterology Department Thierry Ponchon 900 Quality of Life QOL
116. Copyright C Shared Research Inc All Rights Reserved 7777 SR Research Report 2015 1 7 3 D Matrix Inc 1009 6 3 D Matrix Europe SAS 1009 3 D Matrix Asia Pte Ltd 100 3 D Matrix Da America Latina Representacao Comercial Ltda 100 u 100 Com CE 3 D Matrix AsialPte Ltd SG 3 D Matrix Da America be Representacao Comercial Ltda BR Shared esearch http Www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 7777 SR Research Report 2015 177
117. sShared 6Qesearch http Wwww sharedresearchjp Copyright C Shared Research Inc All Rights Reserved PF Shared 6Qesearch http Www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 7777 SR Research Report 2015 1 7 2014 1 14 PuraStat CE 2014 10 30 Pamela Youde Nethersole Eastern Hospital PYNEH 11 6 Chung Ngai TANG M D Chief of Service Department of Surgery and Director of Minimal Access Surgery Training Centre of PYNEH PYNE 5 000
118. RADA16 Shared Research http Wwww sharedresearchjp Copyright C Shared Research Inc All Rights Reserved amp SR Research Report 2015 177 7777 4 54e a se I Ill my 2 AA A mi 10 1 4 1 8 Shar od
119. 3 D Matrix Inc PuraMatrix 2007 10 3 D Matrix Inc 2008 2 Becton Dickinson and Company SUPPLY AGREEMENT PuraMatrix RADA16 T Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 7777 SR Research Report 2015 1 7 2008 3 2008 10 TDM 621 2009 4 2009 7 TDM 62
120. Shared 6Qesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 86 85 we s Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 7777 SR Research Report 201571 7 DDS Drug Delivery System
121. TDM 621 CE 3 D Matrix Europe SAS TDM 621 CE 2014 1 14 EU TDM 621 1 000 ASEAN 2014 3 2013 6 13 s Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w s Shared esearch
122. a ci HOA htt Www aAra manar aieur ry 2m banagr sling htm TDM 711 TDM 711 TDM 711
123. 3 SW Strengths Weaknesses Shared 7777 EPS EPS DPS BPS SR Research Report 2015 1 7 10 4 11 4 12 4 13 4 14 4 15 4 402 158 1 107 32 107 10 418 60 6 599 5 97 1 234 7 467 641 753 1 031 1 626 37 2 17 5 36 9 57 6 65 482 354 999 1 518 4 483 32 09 60 510 310 978 1 524 4 466 28 0 61 534 309 978 1 525 3 564 27 9 13 568 15 168 18 355 18 936 19 876 4 5 35 2 18 4 52 6 77 8 179 3 17 3 86 0 75 1 156 3 53 7 146 2 544 589 1 758 2 033 2 641 594 666 2 501 2 484 3 593 7 6 88 107 103 19 22 30 47 86 578 505 437 383 339
124. FDA T Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w s Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 7777 SR Research Report 2015 1 7 u TDM 641 PMDA RPN 2 2011 Phase I NEDO 2010
125. 2012 4 1 107 1 TDM 621 2 TDM 641 3 753 354 3 14 26 48 310 309 2012 4 300 gt Shared csearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 2011 4
126. 200 400 u 2010 9 300 600 Excelsior Medical Co Ltd Daewoong Pharmaceutical Co LTD u 2011 10 1 352 700 u 2013 7 2 289 550 2014 7 5 051 1 270 s Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 7777 SR Research Report 2015 1 7 1 10 4 11 4 12 4 13 4 14 4 8 5 9 5 4 588 8 9 468 0 19 876 4 EPS 7 870 6 58 896 1 73 7 105 3 77 8 EPS 69 0 DPS 0 0 0 0 0 0 0 0 0 0 BPS 137 634 2 120 159 5 625 1 107 3 146 2 1 600 13 568 15 168 18 355 18 936 19 876 EPS 4 5 35 2 18 4 52 6 77 8 EPS 17 3 DPS 0 0 0 0 0 0 0 0 0 0 BPS 86 0 75 1 156 3 53 7 146 2
127. 955 3 5 18 396 1 518 1 005 5 488 4 483 43 0 1 524 985 5 451 4 466 S 42 9 1 525 1 148 4 712 3 564 SR 2015 4 10 418 4 483 4 466 3 564 TDM 621 50 55 TDM 621 SR TDM 621
128. SR u 2011 7 1 100 948 u 2011 8 1 4 3 792 u 2012 9 1 2 9 222 u 2013 6 1 2 18 936 2013 4 651 200 651 200 2013 4 9 468 000 6 9 2013 6 a A Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 60 85 7777 SR Research Report 13 4
129. 2014 1 14 PuraStat CE CE CE EU 28 0 2014 6 3 CE Health Sciences Authority 3 D Matrix Asia Pte Ltd CE PuraStat 2014 9 1
130. PuraStat TDM 621 TDM 621 2014 12 22 TDM 621 7777 SR Research
131. 2016 4 2014 4 2 015 4 2016 4 2013 5 2013 5 30 PT Teguhsindo Lestaritama TDM 621 3 D Matrix Asia Pte Ltd PT Teguhsindo Lestaritama 2013 5 29 2013 5 28
132. u 2014 4 2016 4 2014 4 4 178 4 747 1 658 2 055 1 646 2 049 1 491 1 752 2015 4 8 474 8 006 3 347 3 521 3 341 3 515 2 241 2 222 2016 4 12 569 5 780 5 780 sShared 6Qesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved amp 7777 SR Research Report 2015 1 7 3 668 2014 4 2014 4 2015 4
133. PT Teguhsindo Lestaritama u TDM 711 2012 2 15 FDA u TDM 641 PMDA 2014 4 TDM 621 2014 4
134. 3 2014 2 2 3 2014 5 12
135. PMDA PMDA 2014 12 11 EMR ESD 7 PMDA TDM 641 2015 4 2 2015 4 2 2014 12 3
136. B Bridge International B Bridge 3 D Matrix Inc PanaceaGel 2 B Bridge 3 D Matrix Inc PanaceaGel 3 D Matrix Inc MIT 3 D Matrix Inc Shuguang Zhang 2014 1 15
137. 03 5834 8787 http www sharedresearch jp Email info sharedresearch jp 4 90 85 Shared GYesearch http Www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved
138. 2014 10 FDA 510 k 2015 510k sShared eSsearch http Www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved amp 7777 SR Research Report 201571 7 510 k DDS DDS bFGF PDGF
139. 15 FDA u TDM 641 s Shared 6Qesearch http Www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 7777 SR Research Report 201571 7 10 4 11 4 12 4 13 4 14 4 402 158 1 107 32 107 60 69 599 596 97 196 234 796 1 2 3 0 3 111 233 251 395 599 355 406 499 636 1 024 467 641 753 1 031 1 626 65 482 354 999 1 518 32 0 11 0 3 38 32 5 27 48 17 38 60 510 310 978 1 524 28 0 6 3 1 21 1 1 2 61 534 309 978 1 525 27 9 SR
140. 2014 11 4 PuraStat5 2014 1 14 PuraStat CE 2014 10 30 Hospital San Borja Arriaran Clinica Las Condes Hospital San Borja Arriaran Cristian Baeza M D 2014 10 23 TDM 511 510 k
141. 2015 1 7 10 4 11 4 12 4 4 PjlcD i 1 28 434 131 2 13 18 100 FCF 1 2 40 452 231 573 498 1 400 A 75 79 79 B 10 90 C 1 20 FCF NI A B C 467 318 SR 647 56 703 983 86 36 210 1 139 1 680 83 1 763 2 360 102 485 1 948 http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved
142. MIT u 1 4 1 MIT MIT 2 3 4
143. CE 2014 8 26 Heart and Diabetes Center NRW Clinic for Thoracic and Cardiovascular Surgery Michiel Morshuis MD 5 000 2014 8 8 2014 8 8
144. MIT 2003 4 15 2017 7 21 a lt PuraMatrix WO 06 014570 2008 _ _ 316133 8 US 5955343 MIT 1999 9 21 2014 8 21 PuraMatrix 0 US 6800481 MIT 2004 10 5 2017 3 25 PuraMatrix PuraMatrix 2 De US 7098028 MIT 2006 8 29 2023 3 16 IS 74491 2008 11 2021 2 PuraMatrix RI lu MT 1 0 30 02 EP 717398 2008 12 31 2022 2 5 PuraMatri US 7713923 MIT 2010 5 11 2024 6 24 A PuraMatrix USPD05 0287186 MIT PuraMatrix 507629 MIT 2012 9 5 PuraMatrix
145. 2018 4 200 2014 11 2016 4 800 2015 4 u 1 600 000 u u 2014 6 24 2014 6 26 u 0 90 1 00 u u Mizuho International Plc 2014 7 9 Shared 6Qesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 63785 we s Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 7777 SR Research Report 2015 1 7 2014 6 20
146. 1999 JASDAQ 7774 2002 2370 COO 2003 10 2005 2007 1998 1 2005 2007 2012 7 INSEAD MBA 1996 2006 CSBA
147. 3 D Matrix Inc 70 2019 4 u 2007 10 579 1 448 3DM Investmen LLC Massachusetts Institute of Technology u 2009 11 500 1 250 4 JAIC TAIB JAIC Asian Balanced Private Equity Fund u 2010 9
148. TDM 621 PMDA ISO13485 TDM 621 FDA IDE Investigational Device Exemption CE EU EU CE u TDM 711 2012 2
149. http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 7777 SR Research Report 2015 1 7 2013 7 2013 7 31 2013 7 5 SMBC 2013 7 5 2013 7 23 2014 4 1 4 069 2013 4 2 003 1 167 1 166
150. 4 7796 u 1 4 162 u 5 286 u 1 3 977 5 u 5 051 2014 6 24 CE 8 0 2014 5 31 19 914 800 6 283 3 000 2018 4 800 2015 4 2017 4 2 800 2014 8
151. 1 4471 2010 6 18 2011 12 2014 1 TDM 621 7777 SR Research Report 2015 1 7 FDA 2015 4
152. FDA D D Asp COOH NH2 A A Ala R R Arg ADME ADME Absorption Distribution Metabolism
153. 1 198 1 199 3 055 3 020 4 121 12 16 22 48 92 31 49 112 913 958 0 55 42 29 31 49 167 955 988 1 167 1 150 2 888 2 066 3 133 ROA ROE 28 434 131 647 1 680 13 18 100 56 83 573 498 1 400 983 2 360 LE 6 3 44 6 14 5 32 2 42 7 6 6 46 3 15 4 39 9 61 8 97 4 95 0 93 9 67 3 70 5 SR eSsearch http Www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved T Shared Wesearch http Www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 7777 SR Research Report 2015 1 7 2015 1 7 2014 12 22
154. Excretion ADME 4 64 85 s Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 7777 SR Research Report 201571 7 SiRNA 21 23 RNA siRNA RNA RNAi RNA mRNA siRNA MTA Material Transfer Agreement
155. 1 975 1 783 999 1 518 4 483 6 796 8 213 978 1 524 4 466 6 779 8 196 978 1 525 3 564 4 678 5 450 SR TDM 621 TDM 621 2015 4 TDM 621 2016 4 14 307 6 796
156. Scaffold GLP Good Laboratory Practice pH
157. Shared 9esearch 2 SR Research Report 201571 7 7777 sr_inquiries Gsharedresearch jp 7777 SR Research Report 2015 1 7 3 SRE 4 RS 5 REPRSSRREE ES 5 RS SESE RR 10
158. search http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 7777 SR Research Report 2015 1 7 SW Strengths Weaknesses Strengths u MIT u u
159. 00 RATEMN MRMN 9 200 6 058 eooo 214811 5 914 5 931 180 176 3 174 2 1473 0 169 2 168 6 171 0171 3 170 7 5 000 160 4 000 3 000 140 Pr vn nm 320 1 000 mm 6 07 006 09 40F 131F 12F 313 14 2006 2007 2008 2009 we Shared csearch http Www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 8 7777 SR Research Report 2015 1 7 6 2016 1 344 iDATA Research 2016 1 078 millennium 30 509
160. 014 12 EMR ESD 260 6 2015 2016 2012 2 TDM 631 RADA16 TDM 631 sShared esearch http Www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved amp sy Shared Gewearch ht
161. 015 1 7 SU C TDM 641 2012 2 20 2014 9 2014 9 3 PuraStat 3 DMatrix Asia Pte Ltd PuraStat 2014 9 3
162. 04 5 19 2011 10 24 HP http www 3d matrix co jp index html 4 TIR IR http www 3d matrix co jp ir index html e 1 Shared 8 esearch la http Wwww sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 89 85 w 7777 SR Research Report 2015 1 7 SR
163. 1 2009 8 TDM 621 PMDA 2010 1 TDM 621 2010 8 13B1X10105 2010 9 3 D Matrix Inc TDM 711 IDE FDA Daewoong Pharmaceutical Co LTD PARTNERSHIP AGREEMENT TDM 621 Excelsior Medical Co Ltd LICENSE AGREEMENT TDM 621 2011 5 TDM 621 TDM 621 PMDA TDM 621 PMDA 2011 7 3 D Matrix Inc TDM 711 FDA IDE 2012 2
164. 1 69 39 19 3 7 106 19 222 221 232 349 297 286 65 996 62 69 40 796 73 29 33 69 6 29 3 321 356 372 470 438 567 4 483 3 341 361 357 466 471 514 4466 341 361 357 467 635 514 3 564 S SR 2015 4 2 2015 4 2 0 49 1 004 676 984 701 1 148 701 422 49 2 583 31 5
165. 14 7 1 St John of God Hospital St John of God Hospital Department of Surgery Bernhard DAUSER M D 4 000 2014 6 2014 6 25 u 1 270 000 1 600 000 68 85 7777 SR Research Report 2015 1 7 u 21 184 800 21 514 800 u 5 016 6 283 u 4 84
166. 5 437 383 339 604 533 554 536 528 1 198 1 199 3 055 3 020 4 121 12 16 22 48 92 4 24 30 43 37 15 9 59 821 829 31 49 112 913 958 0 55 42 29 0 55 42 29 31 49 167 955 988 1 109 1 359 2 070 2 139 3 339 1 099 1 349 2 060 2 129 3 329 1 063 1 596 1 288 2 266 3 792 1 167 1 150 2 888 2 066 3 133 21 22 3 213 697 544 589 1 758 2 033 2 641 SR http Www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 58 85 7777 SR Research Report 201571 7 2014 4 789 19 2014 4 257
167. 511 nt oF 2014 12 TDM 641 apan oe TOM 631 TOM 711 us ec Shar ed esear ch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved s 7777 SR Research Report 2015 177 2014 11 TDM 621 RADA16 TDM 621 TDM 621 TDM 621 pH
168. Report 2015 1 7 2015 2 2014 6 12 2014 12 11 TDM 641 MIT TDM 641 TDM 641 2014 9 9
169. rch Report 2015 1 7 DDS MTA
170. tp Www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved gt 7777 SR Research Report 201571 7 TDM 631 TDM 631 TDM 631 TDM 631 X TDM 631
Download Pdf Manuals
Related Search