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4. 3 1 1960 Hubel Wiesel 1
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12. x 1 Miyake Y amp Awaya S Stimulus deprivation am blyopia Simultaneous recording of local macular electroretinogram and visual evoked response Arch Ophthalmol 102 998 1003 1984 2 Hess RF Thompson B et al Deficient responses from the lateral geniculate nucleus in humans with amblyopia Eur J Neurosci 29 1064 1070 2009 3 Sugiyama S Di Nardo AA et al Experience dependent transfer of Otx2 homeoprotein into the visual cortex activates postnatal plasticity Cell 134 508 520 2008 4 Wygnanski Jaffe T amp Levin AV The effect of the randomized trial of patching regimens for treatment of moderate amblyopia on pediatric ophthalmologists 3 Year outcome J AAPOS 11 469 472 2007 5 Cotter SA Edwards AR et al Treatment of anisome tropic amblyopia in children with refractive correction Ophthalmology 113 895 903 2006 6 Pediatric Eye Disease Investigator Group A ran domized trial of atropine vs patching for treatment of moderate amblyopia in children Arch Ophthalmol
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14. T 107 0052 9 6 41 Phone 03 3475 5618 Fax 03 3475 5619 E mail info jaacc jp Copyright Clearance Center Inc 222 Rosewood Drive Danvers MA 01923 USA Phone 978 750 8400 Fax 978 750 4744 Notice about Photocopying In order to photocopy any work from this publication you or your organization must obtain permission from the following organization which has been delegated for copyright for clearance by the copyright owner of this publication Japan Academic Association for Copyright Clearance JAACC 6 41 Akasaka 9 chome Minato ku Tokyo 107 0052 Japan Phone 81 3 3475 5618 Fax 81 3 3475 5619 E mail info Gjaacc jp 2009 7 ml 11 18 5 5
15. 30 35 43 2009 RA Even though it is commonly known that palpebral fissure width influences non contact tonometer measurement the phenomenon has not been quantitatively analyzed A numerical simulation was carried out using a workstation whose performance has improved remarkably in recent years though the application of computational fluid dynamics without using special equipment such as a high speed camera Palpebral fissure width decrease causes increase in the measured value resulting in measurement error Analysis results showed that palpebral fissure width narrower than a critical value accelerated the increase in measured intraocular pressure value Though it has been generally accepted that the strong air jet from the non contact tonometer deforms the corneal surface present results imply that pressure wave impingement on the eye surface contributes partly to shape deformation For the first time the present study reveals this me
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22. 19 1 2 1 2 4 0 amp lHU 2009 7 Association for Research in Vision and Ophthalmology ARVO ARVO 1
23. No Title Author s Affiliation Reprint requests to Al RIES OLA Key Words No B H SR H H AGE H AGE H HESS H JEU H
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32. Pats JUN He HO PR EE Hi WERE Rit Jy MERAK 2009 7 ER New Wave of Research in Amblyopia Miho Sato Department of Ophthalmology Hamamatsu University School of Medicine 30
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85. 1 20 1 Reprint requests to Miho Sato Dept of Ophthalmol Hamamatsu Univ School of Med 1 20 1 Handayama Higashi ku Hamamatsu 431 3192 Japan Received and accepted June 30 2009 K1 ROHH 1 ametropic amblyopia 2 anisometropic amblyopia 3 strabismic amblyopia 4 form deprivation amblyopia
86. JOEM http www joem or jp moushikomi htm 105 0011 3 5 22 TEL 03 3435 9321 FAX 03 3435 9567 E mail info joem or jp amp h JOEM 2009 7 50 2009 10 H 17 H 18H H A 3 000 10 18 10 17 CE OCT 10H 18H H 13 30 qui YI Hb sp 10 18
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88. 30 19 23 1976 C60 1 6 281 285 2001 5 Steger JL amp Sorenson RL Automatic mesh point clustering near a boundary in grid generation with elliptic partial differential equations Journal of Computational Physics 33 405 410 1979 6 2031 1995 7 ZR 2003 20030017 2003 8 265 281 HOR 2004 4 30 2 W 1 HCL HCL 1 T
89. 30 2 8 t RUM quality of life 1 45 165 167 2003 2 Alharbi A amp Swarbrick HA The effects of overnight orthokeratology lens wear on corneal thickness Invest Ophthalmol Vis Sci 44 2518 2523 2003 3 51 2 12 2009 4 Matsubara M Kamei Y et al Histologic and histochemical changes in rabbit cornea produced by an orthokeratology lens Eye amp Contact Lens 30 198 204 2004 5 Soni PS Nguyen TT et al Overnight orthokeratology Visual and corneal changes Eye amp Contact Lens 29 137 145 2003 6 Orthokeratology IOL amp RS 19 168 173 2005 7 Ladage PM Yamamoto N et al Pseudomonas aeruginosa corneal binding after 24 hour orthokeratology lens wear Eye amp Contact Lens 30 173 178 2004 8 Hiraoka T Okamoto C et al Contrast sensitivity functio
90. 6A 26H 28 H HAAABRS HAIRY 7 Zi Asia Pacific Association of Cataract and Refractive Surgeons APACRS Annual Meeting 3 46
91. 8 30 2 QOV quality of vision 130 7
92. NHK HOYA 50 ii E 30 2 29 1 EBM evidence based medicine
93. 1 2 NS lH 0 1 1 msec mmHg m sec 0 00 0 0 0 00 2 50 20 0 67 11 2 msec mmHg m sec 0 00 0 0 0 00 5 70 110 0 157 39 v r t k Umax Rr yt 5 RIL NCT 7 2 ea NO ei ak ox dy an atm ay Q
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97. OCT fe The Development Process for New Retinal Therapies Stephen J Ryan Doheny Eye Institute 1 m IERA 2 3 IOL 4 3 E 5 3 SLASH 6 7
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99. 10 Il 12 13 3 2 3 et al 1 1 1 10 1990 2 Yamaguchi L Yamane J amp Yagi K Researches on accommodation Physiol Opt 1 1 10 1990 3 Yamaguchi K Physiological Optics 25 30 CV Mosby New York 1990 1 i 30 50 14 4 5 1 15 000 1 AAS 400 3 5 400 1
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112. FAX 03 5216 5552 f E mail jsos33 congre co jp URL http www congre co jp jsos33 2010 3 17 k TEL 03 3238 1041 4 FAX 03 3221 6245 3 20 CE E mail technical meetings jsap or jp URL http www jsap or jp nsu 114 418 Vision Sciences Society Naples Grande Hotel Vision Sciences Society 5 7 10th Annual Meeting 475 Seagate Drive Naples E mail VSSMeeting visionsciences org 5 12 FL USA URL http www visionsciences org meeting html 5 16 H CLEO IQEC 2010 San Jose McEnery Technical Papers staff Convention Center E mail cstech 0sa org 5 21 San Jose California USA URL http www cleoconference org 2009 7 BR Bm 2009 1 2009 4 17 4 16 00 17 30 G504 RE E Mi 10 50 SOP K HER
113. 1 1 238 4 88 1238 24 3638 53A mY 4 uL 2 n 18 p 0 001 ANOVA E p 0 64 ANOVA p 0 05 p lt 0 01 Post hoc test Bonfferoni Dunn 3 2009 7 Matsubara 4 4 2 1 1 0 18 8 T 70 9 2 1 0 12
114. 120 268 278 2002 7 Pediatric Eye Disease Investigator Group A comparison of atropine and patching treatments for moderate amblyopia by patient age cause of amblyopia depth of amblyopia and other factors Ophthalmology 110 1632 1637 2003 8 Holmes JM Edwards AR et al A randomized pilot study of near activities versus non near activities during patching therapy for amblyopia J AAPOS 9 129 136 2005 9 Scheiman MM Hertle RW et al Patching vs atropine to treat amblyopia in children aged 7 to 12 years A randomized trial Arch Ophthalmol 126 1634 1642 2008 10 Gottlob I Awan M amp Proudlock F The role of compliance in 2 vs 6 hours of patching in children with amblyopia Arch Ophthalmol 122 422 423 2004 11 Rahi JS Logan S et al Prediction of improved vision in the amblyopic eye after visual loss in the non amblyopic eye Lancet 360 621 622 2002 12 Scheiman MM Hertle RW et al Randomized trial of treatment of amblyopia in children aged 7 to 17 years Arch Ophthalmol 123 437 447 2005 13 Leinfelder PJ Amblyopia associated with cogenital cataract Am J Ophthalmol 55 527 529 1963 14 Von Noorden GK amp Maumenee AE Clinical observa tions on stimulus deprivation amblyopia amblyopia ex anopsia Trans Am Ophthalmol Soc 65 244 255 1967 15 Travi GM Schnall BM et al Visual outcome and success of amblyopia treatment in unilateral small posterior lens opacities and lenticonus
115. 659 E n Q E n Steger Sorenson 5 7msec 110mmHg 2 5msec fe IRE 20mmHg 4 2 256 X 512 30 2 10 100 1 000 4
116. Wade 9 24 AK Seatle WA USA E mail wade wadelab net 9 27 CE URL http www osavisionmeeting org conf index php 2009 VM2009 Frontiers in Optics 2009 Fairmont San Jose General Attendee Information OSA 170 South Market Street c o OSA Customer Service FiO LS 10 11 H San Jose CA Management 10 15 CK The Sainte Claire Hotel E mail custserv osa org 302 South Market Street URL http www frontiersinoptics com San Jose CA USA AAO Joint meeting Moscone Center General questions meetings aao org 10 24 CE with the Pan American Administrative Office URL http www aao org meetings 10 27 Association of 747 Howard Street 5th annual_meeting sanfrancisco cfm Ophthalmology PAAO Flr San Francisco CA Optics amp Photonics Japan 11 240K 2009 TEL 03 3238 1043 11 26 FAX 03 3221 6245 E mail osj vesta ocn ne jp 30 2 20107 1723 BiOS SPIE Photonics Moscone Center Customer Service g West San Francisco CA USA E mail CustomerService SPIE org 1 28 A URL http spie org x13196 xml 33 1 22 4 TEL 03 5216 5318 124 B
117. factor NGF prevents the shift in ocular dominance distribution of visual cortical neurons in monocularly deprived rats J Neurosci 12 4651 4662 1992 35 Carmignoto G Canella R et al Effects of nerve growth factor on neuronal plasticity of the kitten visual cortex J Physiol 464 343 360 1993 36 Gu Q Involvement of nerve growth factor in visual cortex plasticity Rev Neurosci 6 329 351 1995 37 Fagiolini M Fritschy JM et al Specific GABAA circuits for visual cortical plasticity Science 303 1681 1683 2004 38 Fagiolini M amp Hensch TK Inhibitory threshold for critical period activation in primary visual cortex Nature 404 183 186 2000 39 Hensch TK amp Stryker MP Columnar architecture sculpted by GABA circuits in developing cat visual cortex Science 303 1678 1681 2004 40 Morishita H amp Hensch TK Critical period revisited Impact on vision Curr Opin Neurobiol 18 101 107 2008 41 Gottlob I amp Stangler Zuschrott E Effect of levodopa on contrast sensitivity and scotomas in human amblyopia Invest Ophthalmol Vis Sci 31 776 780 1990 42 Leguire LE Rogers GL et al Levodopa and childhood amblyopia J Pediatr Ophthalmol Strabismus 29 290 298 1992 30 2 43 Leguire LE Rogers GL et al Occlusion and levodopa carbidopa treatment for childhood amblyopia J AAPOS 2 257 264 1998 44 Procianoy E Fuchs FD et al The effect of increasing d
118. initially treated nonsurgically J AAPOS 9 449 454 2005 16 Hubel DH amp Wiesel TN Receptive fields of single neurones in the cat s striate cortex J Physiol 148 574 591 1959 17 Hubel DH amp Wiesel TN Receptive fields binocular interaction and functional architecture in the cat s visual cortex J Physiol 160 106 154 1962 18 Wiesel TN amp Hubel DH Effects of visual deprivation on morphology and physiology of cells in the cats lateral geniculate body J Neurophysiol 26 978 993 1963 19 Hubel DH amp Wiesel TN Binocular interaction in striate cortex of kittens reared with artificial squint J Neurophysiol 28 1041 1059 1965 20 Albus K A quantitative study of the projection area of the central and the paracentral visual field in area 17 of the cat II The spatial organization of the orientation domain Exp Brain Res 24 181 202 1975 von Noorden GK Histological studies of the visual system in monkeys with experimental amblyopia Invest Ophthalmol Vis Sci 12 727 738 1973 von Noorden GK amp Middleditch PR Histology of the monkey lateral geniculate nucleus after unilateral lid closure and experimental strabismus Further observations Invest Ophthalmol Vis Sci 14 674 683 1975 23 von Noorden GK Crawford ML amp Levacy RA The lateral geniculate nucleus in human anisometropic amblyopia Invest Ophthalmol Vis Sci 24 788 790 1983 24 von Noorden GK amp Crawford ML The lateral geniculat
119. subjects Trans Am Ophthalmol Soc 101 401 415 2003 54 Algaze A Leguire LE et al The effects of L dopa on the functional magnetic resonance imaging response of patients with amblyopia A pilot study J AAPOS 9 216 223 2005 55 von Noorden GK Amblyopia A multidisciplinary approach Proctor lecture Invest Ophthalmol Vis Sci 26 1704 1716 1985 56 Hensch TK Critical period plasticity in local cortical circuits Nat Rev Neurosci 6 877 888 2005 2009 7 RRID 2 EHE REPE BR AB 8 ERE Sr D D Hydrodynamic Analysis of Palpebral Fissure Width Influence on Non Contact Tonometer Measured Value Tomoaki Ohshima and Satoki Ueno Oshima Eye Clinic Department of Ophthalmology St Marianna University School of Medicine
120. 27 34 2009 Amblyopia is one of the leading causes of unilateral or bilateral visual impairment in children The experiences of clinicians have been confirmed by basic researchers changes and evidence found by basic researchers has been used by clinicians The mechanism of visual development is being investigated intensively In particular the basic science of amblyopia has been remarkable development in the last decade The classic knowledge of amblyopia may be reconsidered in some aspects In this article summarize the clinical and basic studies of amblyopia Jpn J Vis Sci 30 27 34 2009 Key Words Amblyopia Sensitve period Pharmachological treatment Lateral geniculate Li U REC 2 3 sensitive period critical period
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122. IC GABA CHS GABA glutamic acid decarboxylase GAD 8096 20 GABA USED O GABA GABA 0 PV GABA GABA A C GABA A 4259 ORM
123. ISSN 0916 8273 Jpn J Vis Sci Vol 30 No 2 2009 tis OFF JAPANESE JOURNAL OF VISUAL SCIENCE AE HE 30 2 H X gt et 25 PELO Lo Saree Ros ii LL LLL LLLI 26 lt gt HABENDAS Ie eS sect erent lca ocd ous reti Hle rad i pulpa aes 27 hm x tes a 203 JE IRE at OW REALS 5 2 EEO SUI B RET E 035 gt 44 gt American Society of Cataract and Refractive Surgery ASCRS 2009 47 113 5 EK 49 Association for Research in Vision and Ophthalmology ARVO M MP 51 Gb
124. Laser follow up AO lum AO SLO AO OCT Drexler OCT C inj dox FD OCT OCT 1 um OCT Drexler de Boer
125. chanism by means of a method other than experimental Jpn J Vis Sci 30 35 43 2009 Key Words Non contact tonometer Eyelid Hydrodynamic analysis Pressure wave 1 Dull 8 GAT NCT Tu CHEE j NCT 251 0011 2008 11 20 Reprint requests to Tomoa 4 5 18 Watanai Fujisawa 2 4 5 18 ki Ohshima Oshima Eye Clinic 51 0011 Japan Received and accepted November 20 2008 ABER
126. e nucleus in human strabismic amblyopia Invest Ophthalmol Vis Sci 33 2729 2732 1992 25 Derrington AM amp Hawken MJ Spatial and temporal properties of cat geniculate neurones after prolonged deprivation J Physiol 314 107 120 1981 26 Crawford ML amp von Noorden GK Shrinkage and recovery of cells of the lateral geniculate nuclei with prism rearing in macaques Behav Brain Res 79 233 238 1996 27 von Noorden GK amp Crawford ML The effects of total 21 22 unilateral occlusion vs lid suture on the visual system of infant monkeys Invest Ophthalmol Vis Sci 21 142 146 1981 28 Harwerth RS Smith EL 3rd et al Multiple sensitive periods in the development of the primate visual system Science 232 235 238 1986 29 Kiorpes L Boothe RG et al Effects of early unilateral blur on the macaque s visual system I Behavioral observations J Neurosci 7 1318 1326 1987 30 Taylor DV Critical period for deprivation amblyopia in children Trans Ophthalmol Soc UK 99 432 439 1979 31 Awaya S Sugawara M amp Miyake S Observations in patients with occlusion amblyopia Results of treatment Trans Ophthalmol Soc UK 99 447 454 1979 32 Parks MM Visual results in aphakic children Am J Ophthalmol 94 441 449 1982 33 Birch EE Cheng C et al The critical period for surgical treatment of dense congenital bilateral cataracts J AAPOS 13 67 71 2009 34 Maffei L Berardi N et al Nerve growth
127. n and ocular higher order aberrations following overnight orthokeratology Invest Ophthalmol Vis Sci 48 550 556 2007 9 46 169 171 2004 10 Cho P Cheung SW et al The longitudinal orthokeratology research in children LORIC in Hong Kong A pilot study on refractive changes and myopic control Curr Eye Res 30 71 80 2005 2009 7 American Society of Cataract and Refractive Surgery ASCRS 2009 ASCRS 4 3 8 4 3 Cornea day Glaucoma day 4 4 Erin Jacobson Joel K Shugar EAR STU Film Festival BL
128. nchrony dual optic 2 T 32D FDA Food and Drug Administration UBM ultrasound biomicroscopy aberrometer IntraLase AMO LenSx Lasers intracor conic intrastromal relaxing incision
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