欧州食品安全機関（EFSA：European Food Safety Authority）
Contents
1. 2008 10 31 FDA Science Board http wwwr fda govohrms dockets ac 08 briefing72008 4386b1 mdex html BPA http 7 wwwr fda gov7ohrms dockets ac 08 briefing 2008 4386b1 05 pdf GLP 0 characterization2. BPA BPA 41 http www hc sc gc ca fn an pubs securit bpa_survey enquete eng php NN A 122 122 23 99 809 BPA 15 0 18 ng g 70 1 0 ng g 0 95 ng g
3. A CRPA 1999 toxic 18 A A
4. 2 5 A BPA Bisphenol A BPA and food packaging May 2009 FSANZ 39 http wwwr foodstandards govau newsroom factsheets factsheets2009 bisphenolabpaan dfood4218 7 Wo 72 009 3 FSANZ BP FSANZ 18 cfm 2 4 BPA EFSA BPA EESA E
5. A CPPA 1999 64 64 c A Q amp A Questions and Answers for Action on Bisphenol A Under the Chemicals Management Plan http www chemicalsubstanceschimiques gc ca faq bisphenol a qa qr e html A A A
6. BPA BPA BPA
7. BPA robust 2006 EFSA 3 2002 NOAEL 5 mg kg 2 NOAEL 5 mg BPA kg 2002 500 TDI 0 01 mg kg 2006 5 100 al
8. SCF 1x g kg BPA BPA EE LT E oo et
9. 2008 L 5 23 6 A Government of Canada Takes Action on Another Chemical of Concern Bisphenol A April 18 hc sc gc ca ahc asc media nr cp 2008 2008 59 e html http www 2008 Clement A Baird 4 18 stakeholder A f 19
10. 2014 1 http www nihs go jp hse food info index html 50
11. i NOAEL 47 5 mg kg bw7day LOAEL gt 475 mg kg bw day 5 3 NOAEL 4 75 mg kg bw day LOAEL gt 47 5 mg kg bw day A FDA A H A A HH unlikely
12. challenging 1 A A A
13. CFDA Dr Andrew von Eschenbach The FDA this Week Andy s Take http wwwr fda gov oc vonEschenbach andys take default html A October 31 2008 FDA A BPA TDA FDA FDA r 37 FDA
14. 0 1 ng A LC MS GC MS A 0 6 zgL A 19 87 g L NHANES III 894 2 ul 0 59 A 95 5 18 g L 6 9 A lt 54 3 gL 1 8 2 4 g L A A 1 96 g L A A
15. Bisphenol A in Beruhigungssaugern Untersuchungsergebnisse des BfR Information Nr 039 2009 des BfR vom 03 November 2009 http www bfr bund de cm 216 bisphenol a in beruhigungssaugern untersuchungserg ebnisse_des_bfr pdf 1 No 23 2009 p 24 http www nihs go jp hse food info foodinfonews 2009 foodinfo200923 pdf 3 1 A BPA WHO EAO BISPHENOL A BPA Current state of knowledge and future actions by WHO and FAO INEOSAN Information Note No 5 2009 BisphenolA 27 November 2009 WHO http 7www who int foodsafety publications fS management No_05 Bisphenol A Nov09 _en pdf 47 No 25 009 A BPA robust data
16. 36 FDA A FDA BPA FTDA A 18 BPA
17. 32 NTP 5 some concern minimal concern BPA negligible concern ll FDA 8 1H A 9 16
18. 2 EFSA A EFSA No 3 09 1 EFSA A TDI EFSA re evaluates safety of bisphenol A and sets Tolerable Daily Intake 29 January 2007 http wwwr efsa europa_ eu en press_roompress_release pr_bpa html 1 29 EFSA A BPA BPA 5 BPA i TDI full TDI TDI BPA TDI
19. A A 8 A 170 2008 10 18 60 2009 21 A EFSA CEF 35 AMU
20. A A
21. AFC TDI 100 AFC TDI 0 05 mg kg 2002 TDI 500 substantial 100 2 2 2 4 AFC Opinion of the Scientific Panel AFC related to 2 2 Bis 4 Hydroxyphenyl Propane 29 January 2007 http wwwr efsa europa eu en science afc afc_opinions bisphenol_a html AFC A BPA A 2 2 4
22. a 5 2009 BPA 1 HH CMP BPA BPA 2009 BPA 1 FA E 49 BPA 2008 8 E 1 BPA
23. 2 3 FDA FDA 2 6 padi 3 E FDA FDA BPA FDA mg kg bw 7day BPA 1 RB
24. BPA AFC U U iR U 10 1000 BPA H A
25. 50 40 5 1 BPA BfR AGES BPA 4 5kg 1 12 BPA TDI 1 BPA BPA BfR BPA BPA
26. A NTP neghigible concern A A 2 A A NTP A
27. A robust lt A f E bps6 F pan
28. safe hmit 5 NZFSA FSANZ BPA FE ia cf EFSA BPA 60
29. neghigible concern NN minimal concern CERHR 13 f A E E A
30. Canada Gazette Part 1 75 1 No 22 2008 p 30 http 7wwwr nihs go jp hse food info foodinfonews 2008 foodinfo200822 pdf 27 A No 15 0 1 A Survey of Bisphenol A in Baby Food Products Prepackaged in Glass Jars with Metal Lids July 2009 http wwwr hc sc gc ca fn an securitpackag emball bpa bpa_survey summ enquete eng php 122 A BPA BPA BPA BPA
31. A TDI A A BfRR Q A A BfR 2
32. BfR A 173 A BfR 2 BfR A 45
33. 0 16 g kg conservative 7g 0 04 0 08g g kg RAR E SCF E SCF BPA BPA 6 BPA H
34. A 10 0 001 mg kg bw day 0 0016 mg kg bw day 0 00037 0 00048 mg kg bw day 100m g kg bw day bw day lt 0 002 pg 0 45 g kg bw day y 5 4 0 043 g kg A
35. A NTP some concern NTP NTP 7 A Bisphenol A BPA
36. 2 A A 16 A A A
37. A A A BfR 43 Q A A A TDI 0 05 mg kg 100 TDI
38. Q A A A A BfR BfR EFSA FDA BfR Q A A
39. 2007 E 8 CERHR E FDA FDA BPA ai 1 11zg 1 7 g FDA BPA f FDA
40. H A 1 robustness GLP A
41. PSC BPA 4 BPA E FSC E FSC web NOAEL mi A MHLW 2008 BPA 1998 3
42. TFDA FDA TFDA TDA FDA FDA
43. Association of urinary bisphenol A concentration with medical disorders and laboratory abnormalities in adults Lang TA et al JAMA 2008 Sep 17 300 11 1303 10 Epub 2008 Sep 16 2 2 A BPA FDA FDA Statement on Release of Bisphenol A BPA Subcommittee Report October 28 2008 FDA http www fda gov bbs topics NEWS 2008 NEW01908 html o 29 008 FDA 2008 8 BPA FDA Science Board subcommittee BPA Subcommittee report 10 81 TFDA NN FDA A
44. TFDA v 23 A 13 November 2008 AFSSA http wwwr afssa fr PM9100C310 htm No 24 008 EFSA 2006 A TDI 0 05 mg kg EFSA A 1L 50gg AFSSA A
45. E NOAEL FDA BPA BPA EE 1 No 11 2008 n 8 No 25 2007 http www nihs go jp hse food info foodinfonews 2007 foodinfo200725 pdf 4 21 CFRS170 3 Safe or safety means that there is reasonable certainty in the minds of competent sclentists that the substance is not harmful under
46. A 1 code of CEPA Canadian Environmental Protection Act 1 14 A A A A Minister s Remarks on Bisphenol A http wwwr hc sc gc ca ahc asc minist speeches discours 2008 04 18 e html 2006
47. 10 20 5 FDA BPA FSANZ BPA EFSA FDA BPA FSANZ BPA FSANZ
48. 2 f 2002 3 2002 FF AFC AFC E f f j BPA 200 F E AFC TDI TDI BPA TDI ATFC
49. 1 No 11 2008 28 30 http wwwr nihs go jp hse food info foodinfonews 2008 foodinfo200811 pdf 2 No 9 2008 24 25 http wwwr nihs go p hse food info foodinfonews 2008 foodinfo200809 pdf 1 4 A 24 Updated European Risk Assessment Report 4 4 Tsopropyhdenephenol Bisphenol A CAS Number 80 05 7 EINECS Number 201 245 8 Final Approved version awaiting for publcation Environmental Addendum of February 2008 06 28 to be read in conjunction with published EU RAR of BPA 2003 for full details ECB http 7ecb jrc it documents Existing Chemicals RITSK_ASSESSMENT7ADDENDUM bis phenola_add_325 pdf No 14 008 A 2003 II
50. NTP 2 OT some concern some concern some concern minimal concern one step high concern NZFSA NZFSA NZFSA
51. BPA BPA BPA BPA BPA BPA unlikely BPA EFSA BPA BPA 1 safe limit EESA BPA
52. 5 1 A ug criteria A evaluate 640 mg kg day 1 250 mg kg day 450 mg kg bw day 600 mg kg bw day 450 mg kg day 600 mg kg day
53. TDI 5 3 2008 A AFC Toxicokinetics of Bisphenol A Saientific Opinion of the Panel on Food additives Flavourings Processing aids and Materials in Contact with Food AFC 23 07 2008 http wwwr efsa eu int EFSA efsa_ locale 1178620753812_1211902017492 htm AFC BPA BPA BPA BPA 6 BPA
54. A A A A Ausgewahlte Fragen und Antworten zu Bisphenol Ain Babyflaschchen und saugern Aktualhisierte FAQ vom 2 Oktober 2009 http wwwr bfr bund de cm 276 ausgewaehlte_fragen_und_antworten_zu_bisphenol_a_i n_baybflaeschchen_und_saugern pdf 2 9 A Bisphenol Ain dummies 26 October 2009 BR http wwwr bfr bund de cm 230 bisphenol_a_in dummies pdf No 23 009 9 A BfR A
55. A EFSA 2007 1 A TDI 0 05 mg kg bw EESA A 18 9 A Bisphenol A May 2008 NZFSA http wwwr nzfsa govt nz consumers chemicals toxins additives bisphenol a htm Q amp A A BPA BPA BPA BPA
56. BfRR BPA i 2007 EFSA TDI 0 05 mg kg 2 BfR BPA EFSA TDI 0 05 mg kg BfR EFSA
57. 48 TDI 0 05 mg kg FDA 1 2 2008 NTP f CERHR BPA FDA BPA NOAEL 2 0 185 7 g kg mg kg bw 27 000 j 3 2 5 ppm TDI 0 05 mg kg 20
58. some concern minimal concern minimal concern 2 F En 3 Ph N negligible concern some concern minimal concern negligible concern J minimal concern 5 5 f PBPK 1 2 8 4 5
59. BPA PC PC BPA conservative 1 PC 6 18 7 g kg 50 g BPA 8 8 g
60. BPA 2009 EHP BPA BPA FSANZ BPA 5 12 gt BPA A A
61. uh a 44 Q A BfR A BfR A BfR Q A A A Q
62. some concern 6 NTP BSC minimal concern EFSA No 16 2008 FDA No 18 2008 BPA 33 1 9 A Neue Studien zu Bisphenol A stellen die bsherige Risikobewertung nicht in Frage 19 09 2008 BfR http 7 7wwwr bfr bund de cm 216 neue_studien_zu_bisphenol_a_stellen_die_bisherige_ris 1kobewertung_nicht in frage pdf Ao 20 008 A BPA 2
63. 60 nj A R A f 13 A practicee A E A 2008 4 18
64. BfR 1 Q A A A TDI 0 01 mg kg TDI A OO A
65. 2008 lt ul 83 A Survey of Bisphenol A in Canned Powdered Infant Formula Products July 2009 42 http 7 www hc sc gc ca fn am pubs securit bpa_survey enquete pow pou eng php 2008 6 6 11 38 31 7 0 13 ng g A 28 A Q amp A 2009 10 2 Selected questions and answers on bisphenol A in feeding bottles and dummies for babies Updated FAQs 2 October 2009 BfR http wwwr bfr bund de cm 279 selected_quest
66. FSANZ E MI OR Use of Polycarbonate Bottles and Urinary Bisphenol A Concentrations Jenny L Carwile Henry T Luu Laura S Bassett Daniel A Driscoll Caterina Yuan Jennifer Y Chang Xiaoyun Ye Antonia M Calafat and Karin B Michels doi 10 1289 ehp 0900604 available at http dx doi org 40 Online 12 May 2009 26 A Giovernment of Canada Acts to Protect Newborns and Infants from Bisphenol A jn Polycarbonate Plastic Baby Bottles June 26 2009 http www hec sc gc ca ahc asc media nr cp 2009 2009_106 eng php No 14 009 A A 1 18 A
67. HDPE PETE 51 BPA 0 5u gL 17 18 BPA 0 50 8 82 g 1 5 gyL BPA TDI 25 g kg BPA 1 5 x g L 60kg TDI 1 000L BPA 1 5z gyL 1 5L BPA 0 18 g kg 0 22 g kg BPA
68. 5 2 42 g kg BPA NOAEL 2 000 5 NOAEL FDA A 5 f EE BPA E E 1990 E BPA SB BPA EE MHLW 4 BPA 2008 4 ES 2
69. FDA BPA OCTFSAN 2007 BPA 2008 4 NTP BPA 2 NTP 6 11 NTP some concern some concern FDA
70. A BfR 50 40C 5 1 0 25xg 5 A 4 5kg 5 0 25ug A TDI 17 A 1 A 10ug 1
71. BPA 0 19 7 22 ng g BPA BPA ONS0 2008 BPA 2 A Survey of Bisphenol Ain Bottled Water Products July 2009 http wwwr hc sc gc ca fn arm securit packag emballbpa bpa_survey enquete bot bou en g Dhp 2008 4 16 21 54
72. j E NOEL 5 FDA 7000 7000 TFDA reasonable certainty of no harm under the intended conditions of use BPA FDA 2007 11 26 NTP CERHR BPA minimal concern 2008 4 14 NTP Draft Brief CERHR some concern 2 22
73. A A Q A A A BfR A BfR EFSA FDA A 0 6 mgykg 60kg A 0 6 mgkg 1 kg A TDI 60kg 8 mg 5 1 BfR Q
74. 10 A EFSA 2006 EFSA 24 A BPA Bisphenol A BPA and food packaging 11 March 2009 FSANZ http www foodstandards gov au lnewsroom factsheets factsheets2009 bisphenolabpaan dfood4218 cfm 38 No 6 009 FSANZ BPA A
75. A Draft Meeting Summary Expert Panel Evaluation of Bisphenol A http cerhrniehs nih gov chemicals bisphenol draftBPA MtgsSumm080807 pdf A some concern minimal concern minimal concern negligible concern A some concermn minimal concern A negligible concern minimal concern A A
76. BPA 2002 AFC 2002 NOAEL 5 mg kg BPA robust BPA BPA BPA robust 2 5 mg kg
77. No 18 2008 FDA Principal Deputy Commissioner Frank Torti FDA NTP FDA NTP NTP 5 serious concern concern some concern minimal concern negligible concern The NTP CERHR Monograph on the Potential Human Reproductive and Developmental Effects of BisphenolA September 2008 http 7 cerhr niehs nih gov chemicals bisphenol bisphenol pdf 5 2008 4 NTP draft brief
78. Gminimal 11 f v 0 dimorphism 1 A positive E sexual EE os 5 some concern
79. 1j E note quality assurance E a pdf 105 BPA 4 BPA 31 2 42 g kg bw OP 5 mg kg bw 2 000 27 000 NN PAM FDA 0 185 gu g kg bw NOAEL NOAEL 1
80. Assessment of four studies on developmental neurotoxicity of bisphenol A http www vkm no eway default aspx pid 266 amp trg MainLeft_5419 amp 4698 5420 2 amp Ma inLeft 5419 5468 17924 0 5420 4 0 0 1 7 FDA A Meeting of the Bisphenol A Subcommittee of the Science Board to the Food and Drug Administration FDA http www fda gov oc advisory accalendar 2008 SciBrdSub91608 htm No 18 008 FDA Seience Board BPA 1 2 2008 9 3 16 DC BPA http wwwr fda gov7ohrms dockets ac 08 briefing 2008 0038b1_ 01 00_imdex htm 2008
81. 3 A A quality quantity strength A 3 2007 CERHR CERHR NTP A
82. A A A A A Q A A A 0 MRSA A A ml
83. ff A 1 Association of urinary bisphenol A concentration with medical dnsorders and 34 laboratory abnormalhities in adults Lang TA Galloway TS Scarlett A Henley WE Depledge M Wallace RB Melzer D JAMA 2008 Sep 17 300 11 1303 10 2 Bisphenol A prevents the synaptogenic response to estradiol in hippocampus and prefrontal cortex of ovariectomized nonhuman primates Leranth C Hajszan T Szigeti Buck K Bober J MacLusky NJ Proc Natl Acad Sci USA 2008 Sep 16 105 37 14187 91 2 0 4A Government of Canada Protects Famihes With Bisphenol A Regulations October 17 2008 http wwwr hc sc gc ca ahc asc media nr cp 2008 2008_167 eng php No 22 008 10 17
84. A BfR A A BfR Bf A Bisphenol A in Beruhigungssaugern http www bfr bund de cm 216 bisphenol a in_beruhigungssaugern pdf 30 A BfR Bisphenol Ain dummies BfR study results 3 November 2009 BfR http 77wwwr bfr bund de cm 230 bisphenol_a in dummies bfr study results pdf No 24 009 BfR 18
85. RAR 2003 RAR http ecb jrc it es1s pgm esis_reponse php LANG en amp FROM LISTE EINECS amp ENTR EE 201 245 8 CAS 80 05 7 A Hinal RAR 2008 Addendum 2008 1 5 A Draft BPA Report Gets Public Comment and Board Review NIREHS Environmental Factor 2008 7 NIEHS http 7 www nnehs nih govmews newsletter critique cfm No 15 008 2008 4 NTP NIEHS A BPA draft brief NTP BSC Board of Scientific Counselors 6 11 12 BPA NTP CERH
86. ALARA WHO FAO BPA 2010 BPA 2010 10 1 EFSA 2006 No 3 2007 p 22 http www nihs go p hse food info foodinfonews 2007 foodinfo200703 pdf 2 EFSA No 16 2008 p 17 http www nihs go jp hse food info foodinfonews 2008 foodimfo200816 pdf 8 FDA A No 18 2008 p 26 http 7wwwr nihs go jp hse food info foodinfonews 2008 foodinfo200818 pdf
87. FDA BPA FDA 1 2 A 5 Bisphenol A EFSA 4 NTP FDA BPA H http wwwr efsa europa eu EFSA KeyTopics efsa_locale 1178620753812 BisphenolA ht Im Ao 72 008 EFSA NTP A 1
88. NOAEL overall NOAEL 5 mg BPA kg 500 BPA NOAEL BPA BPA ORCD 1
89. BPA AFC conservative TDI 3 6kg TDI BPA 4 TDI TDI TDI BPA 2002 SCF TDI 4 ATFC Sc 3 100 yy 2006 10 TDI 0 100 5
90. Hearings Plastic Additives in Consumer Products I http commerce senate gov7public Consumer Affairs Insurance and Automotive Safety May 14 2008 http commerce senate gov public index cfm FuseAction Hearings Hearing amp Hearing _ ID d8894142 44e0 4a06 999c 05811a11938c No 11 008 2 A 2008 5 14 2 TFDA CPSC American Chemistry Council 5 witness EDA
91. A A A uh FI A Phenol 4 4 1 methylethylidene bis Bisphenol A http www ec gc ca substances ese eng challenge batch2 batch2 80 05 7 en pdf
92. A A A 18 A A
93. A 1 2006 1 2009 12 http wwwr nihs go jp hse food info foodinfonews index html A A Q amp A Ausgewahlte Fragen und Antworten zu Bisphenol A in Babyflaschchen 18 01 2006 BfR http www bfr bund de cd 7195 Wo 2 0 A A BfR
94. A BPA BfR 709 1 2 100mL 50mL BPA 46 BPA HPLC 2 MS 1 BPA 0 015 g 0 3 g L BPA 0 05z g 1 gL 18 17 BPA RN a RO ORC DAE TR
95. 6 7 8 9 10 A 5 4 H 12 A 5 NTP A 2008 4 14 Draft NTP Brief on Bisphenol A April 14 2008 Peer Review Date June 11 2008 NTP CERHR http cerhr niehs nih gov chemicals bisphenolBPADraftBriefVF 04 14 08 pdf No 9 008 NTP
96. NZFSA NZFSA 2 10 A BPA Bisphenol A BPA FDA http wwwr fda gov oc opacom hottopics bpa html Ao 77 008 FDA 2008 4 14 BPA FDA TFDA FDA 2008 4 14 NTP concerns
97. E 20 E 5 j EFSA FDA f BPA 1 BPA 0 1 safe limit BPA ed FDA Environmental Health Perspectives A 77
98. ES8 14 A Draft Assessment of Bisphenol A for use in food contact applications Draft version 08 14 2008 http www fda gov7ohrms dockets ac 08 briefing 2008 0038b1_ 01 02 FDA 20BPA 20 Draft 20Assessment pdf BPA BPA BPA H BPA CF BE mixed results BPA BPA iii 30 BPA
99. FDA RFSA AFC BPA FDA BPA BPA 1 1
100. 31 44 LOD 0 9 ng m3 51 5 ng m3 lt 29 ng m3 0 41 lt 0 1 12 rg L 25 100 A detectable 17 6g g A A lt 5 pxg L 18 gL 6 6 g L 6 3 zgL A 89xg kg
101. A FAQ Q A A 2 2 4 Q A A Q A A A Q A A A A
102. BPA EFSA EFSA NZFSA FSANZ 4 unlikely BPA BPA BPA safe level 10 7 No 10 008 E 20 BPA safe limit
103. EFSA 2006 BPA 1 EFSA 2006 Opinion of the Scientific Panel on food additives flavourings processing aids and materials in contact with food AFC related to 2 2 BIS 4 HYDROXYPHENYL PROPANE Adopted date 29 11 2006 http wwwr efsa europa eu EFSA efsa locale 1178620753812 1178620772817 htm No 8 2007 2 NTP Draft NTP Brief on Bisphenol A April 14 2008 Peer Review Date June 11 2008 http cerhr niehs nih gov chemicals bisphenolBPADraftBriefVF 04 14 08 pdf No 9 2008 8 Draft Screening Assessment for Phenol 4 4 1 methylethylidene bis Bisphenol A 80 05 7 April 2008 http wwwr ec gc ca substances ese eng challenge batch2 batch2 80 05 7 en pdf No 9 2008 4 ECB Updated European Risk Assessment Report 4 4 Tsopropyhdenephenol Bisphenol A Final Approved version awaiting for publcation http 7 ecb jrc it documents Existing Chemicals RISK_ ASSESSMENT7ADDENDUM bis phenola_add_ 325 pdf No 14 2008 29 5
104. NTP some concern CERHR NTP some concern A A
105. 148 mg kg day 600 mg kg day 475 mg kg day AA 0 01 0 2 mg kg day A 475 600 mg kg day 5 2 A E 0 0024 mg kg7day A
106. BPA ATEC 2006 TDI 0 05 mg kg bw BPA BPA 2006 AFC BPA BPA 27 AEC 2006 NTP BPA 2 2008 EF
107. BPA BPA BPA BPA A BPA BPA BPA BPA E 3 AFC NOAEL 5 mg kg BPA 4
108. first pass metabolism BPA systemic availability BPA BPA BPA detoxication pathways BPA BPA BPA 20 80 AFC BPA BPA BPA
109. BPA 3 4 21 CFRS170 3G NTP CERHR FDA PK CERHR robust E 5 FDA CERHR hazard identifications FDA GLP statements FDA replhcates
110. A A F EESA 2007 1 A EFESA TDI 0 05 mg kg bw A EFSA EFSA 2008 7 ADI 23 1 3 FDA
111. TDI 0 05 mg kg bw 28 BPA 1 mgykg 20 ETFSA 2006 EU EC 2003 2008 BPA BPA BPA equivalent BPA AFC NOAEL 100 H BPA
112. 500 2 05 mg kg 3 A 2 Bisphenol A Second Expert Panel Meeting NTP CERHR http cerhr niehs nih gov chemicals bisphenol bisphenol mtg html No 18 00 NTP CERHR 2007 8 6 8 A 2 12 A 1 1 2007 3 5 7 RN RI2 4 a 1
113. A FDAs Chief Scnentist Asks Science Board Subcommittee to Review Research on Bisphenol A June 6 2008 FDA http 7 wwwr fda govbbs topics NEWS 2008 NEW01847 html No 13 008 2008 4 FDA A BPA 1 FDA Frank M Torti FDA Science Board head of Health Care Policy Barbara J McNeil BPA BPA FDA BPA FDA FDA Eschenbach
114. BPA TDI FDA BPA JAMA 1 PNAS 2 2 BfR Leranth 2 BPA BPA BPA BPA Lang et al 1 1 455 BPA BPA
115. A 0 08 4 30 g kg bw 0 1 0 50 4 30 g kg bw 12 18 15 0 27 1 75 zg7kg bw 1 2
116. A SS NTP high production volume chemical A A A A CERHR 1 A
117. HH M NTP BPA NTP 1 FDA CERHR 2008
118. Norris Alderson Statement of INorris Alderson Ph D Associate Commissioner For Science Before Subcommittee on Consumer Affairs Insurance and Automotive Safety Committee on Commerce Science amp Transportation United States Senate May 14 2008 http commerce senate gov public fles AldersonEDA 51408BPATestimonyFINALpdf A BPA FDA 4 17 Alderson NTP FDA BPA 21 BPA FDA BPA 2007 99 2007 NTP CERHR BPA BPA
119. BPA NTP BPA 2007 8 NTP CERHR 2 1 2007 11 2 2008 4 NTP 3 2008 6 NTP 2008 NTP CERHR No 18 2007 29 830 2 No 25 2007 41 46 No 9 2008 24 25 BPA NTP BSC Actions on the Draft NTP Brief on Bisphenol A by the NTP Board of Scentific Counselors BSC June 11 2008 http 7ntp niehs nih gov files BSOCactionsBPA_508 pdf NTP 4 BSC BSC some concern 12 0
120. FDA 80 90 H 1 BPA 3 0 NTP A i NTP E H 2 Ne BPA FDA ff EFSA
121. negligible concern concern 1 6 EFSA A EFSA updates advice on bisphenol 23707 2008 EFSA http www efsa eu int RESA efsa locale 1178620753812 1211902017373 htm No 16 008 RESA AFC A BPA BPA 2006 EFSA 1 BPA TDI AFC BPA BPA AFC BPA BPA BPA 1 mg kg bw
122. some concern 10 2 BPA negligible 11 1 negligible consern 12 0 BPA minimal concern 26 11 0 1 BSC OR He some concern minimal concern 7 4 1 NT some concern minimal concern 7 4 1 SE 4 NTP 5 serious concern some concern minimal concern
123. 1 1 http cerhr niehs nih gov chemicals bisphenolIMEETING SUMMARY BPA pdf 4 A Bisphenol A Evaluation NTP CERHR http cerhr niehs nih gov7chemicals bisphenol bisphenol eval html No 25 007 A 2007 11 A ta A NTP CERHR Expert Panel Report on the Reproductive and Developmental Toxicity of Bisphenol A November 26 2007 http cerhr niehs nih gov chemicals bisphenol BPAFinalEPVF112607 pdf 1 2 a 3 4 5 6 5
124. FAQ on Bisphenol A 29 January 2007 http wwwr efsa europa eu en press room questions and answers faq on bisphenol a h tml EU BPA 2002 72 EC 2002 8 6 BPA BPA BPA 1 EFSA BPA 1980 E v BPA 4 BPA 4 EC SCF BPA 2002 E
125. 12 200 A A A precautionary action A A
126. 2008 4 FDA BPA FDA BPA biological fate 2 BPA FDA FDA BPA FDA BPA lt lt 20
127. FC BPA AFC BPA NOAEL 5 mg kg 100 TDI 0 05 mg BPA kg conservative TDI 30 BPA BPA 3 A FAQ
128. R NTP Mike Shelby CERHR regulatory documents NTP 25 CERHR BSC BSC NTP
129. SA NTP 4 2008 EFSA JROC Joint Research Centre ECB EFSA 2006 VKM 2008 5 NOAEL 5 mg kg bw EFSA EFSA NOAEL H
130. Statement of EFSA on a study associating bisphenol A with medical dnsorders Prepared by the Unit on food contact materials enzymes flavourings and processing aids CEE and the Unit on Assessment Methodology AMU 24 10 2008 EFSA http wwwr efsa europa eu EFSA efsa_locale 1178620753812_1211902145465 htm No 23 008 EFSA 9 29 JAMA A BPA Lang JAMA 2008 9 16 EFSA AFC 2006 BPA BPA TDI 0 05 mg kg 7 1 EFSA BPA 2006 AFC TDI
131. and food packaging April 2008 FSANZ http wwwr foodstandards govau newsroom factsheets factsheets2008 bisphenolabpaan 1 17 dfood3898 cfm No 9 008 FSANZ BPA A BPA BPA BPA BPA unlikely BPA RFSA BPA 1 maximum daily safe h
132. ions_and_answers_on_bisphenol_a_in_fee ding bottles_and_dummies_ for babies pdf Ao 22 009 A BfR A FAQ 2009 10 2 Q A A 2 2 4 Q A A Q A A A
133. kg 10 g BPA BPA 10 g 60 kg 2003 EU BPA BPA 2002 BPA NOAEL 5mg kg SCF BPA 7 83 500 TDI 0 01 mg BPA kg Lr E I ii BPA BPA 4
134. mit EFSA BPA 10 20 5 FSANZ EFSA 8 A Update on bisphenol A 25 04 2008 EFSA http www efsa europa eu EFSA efsa locale 1178620753812 1178703466879 htm 7 No 10 008 EFSA NTP A
135. the intended conditions of use 5 No 9 2008 http wwwr nihs go p hse food info foodinfonews 2008 foodinfo200809 pdf 1 8 NTP A NTP finahizes Report on Bisphenol A 3 September 2008 NTP National Toxicology Program http 7 wwwr niehs nih govmnews releases 2008 bisphenol a cfm No 19 008 9 3 NTP A BPA BPA some concern BPA NTP BPA NTP Associate Direc
136. tor John Bucher BPA dismiss CERHR Michael Shelby BPA tt
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