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1. TAR RS MS eo RM 2 8C ON BA 500 G 5 EDTA 1000 G 5 HbAiec DP2. 3 31 61 2 2 41 0 F 3 KA 1 gt 1 HbAlc 100 mAbs HbA1c 1 mo1 1 0 5 6 5 2 mAbs 90 l 1 umol L 0 3 3 0 nAbs gt HbAlc mmol mol IFCC
3. 3 700 nm HbAlc gt HbAlc HbAlc 1 HbAlc 2 570 um 02 I 3 15 25 5 2 8 2 80 MEO gt 1 2 25C 8 2
4. 0 6 3 0 U mL ee 0 15 0 75 mg mL 3 20 U ml 2 gt 800 4000 U mL 10 3 7 ese soe nee eeeeeoeee neereseseee 0 008 0 03 mg mL Alc HbAlc HbAnc llbA1c HbAlc lt HbA1lc gt 1 HbAlc N Va1 His 2 8 N
5. mo1 imol 60 mol mo1 15 60 mno1 nno1 9 mmol mol gt 10 HbA1c 60 mno1 mo1 CV 5 60 mmol mol SD 3 mmo1 mo1 gt HbAlc mmo1 mol HbAlc mmo1 mo1 IFCC 65 130 gw mol L 13 158 mmol mol HbAtc NGSP 3 3 16 6 3 0 16 0 2 66 Y HPLC IFCC mmo1 mo1 r 0 997 y 0 981x 0 38 3 HbA1e JCCRM411 gt 1 2
6. 25A2X00001000008 877433 2012 2 6 2009 12 5 At1c 30168000 HbAic A 2 3 4 HbArc 5 6 1 gt
7. gt HbF gt 1 M 25 mg dL 20 mg dL 1000 mg dL 2000 2 Hb Hb HbA1c gt 2 8 1 gt 1 2 Pr cia 26 51 lt lt 3 2 25 8 gt AU HbAlc
8. 21 1 252 kL 2 63 L 1 1 37C 0 5 9 700 nm 700 nm 750 nm 750 nm 2 21 1 252 uL 37C 0 5 570 nm 700 nm 3 HbAtc mmo1 mo1 HbAlc Qmo1 L HbAlc mmol mol mo1 D HbAlc moe1 L mo1 L SM HbAlc NGSP HbAlc JDS 9 HbAlc NGSP 0 0915 X IFCC mmo1 mo1 2 15 HbA1c JDS 0 980 X HbAlc NGSP 0 245 gt lt gt HbAlc NGSP 4 6 6 2 HbAle JDS 4 3 5 8 2 gt
9. MA aa X gt 2 AS i 1 2 2 8C 12 HbAic 1 1000 mL X 1 2 _1000 mL X 1 1 100_ mL X 1
10. 28 90 mL 4 HhAic 71703 2 10 American Diabetes Association American Diabetes Association Wieland H et al Weykamp C et al 47 1033 1035 1989 Koenig RJ Peterson CM Kilo C Cermami A Williamson JR Hemoglobin Alc as an indicator of the degree of glocose intolerance in diabetes Diabetes 25 3 230 2 1976 Implications of the United Kingdom Prospective Diabetes Study Position Statement Diabetes Care 22 27 31 1999 Tests of Glycemia jn diabetes Position Statement Diabetes Care 21 77 79 1999 Diabetes Control and Complications Trial Research Group The effect of intensive treatment of diabetes on the development and progression of long term complications in insulin dependent diabetes mellitus N Engl J Med 329 977 86 1993 Diabetes Control and Complications Trial Research Group The Absence of a glycemic threshol1d for the development of long term complications The perspective of the diabetes contro and complications trial Diaboctes 45 1289 98 1996 Krishnamurti U Steffes MW Glycohemoglobin A primary predictor of the development or reversal of complications of diabetes mellitus Cl
11. in Chem 47 1157 1165 2001 IFCC Reference System for Measurement of Hemoglobin Alc in Human Blood and the Nationa Standardization Schemes in the United States Japan and Sweden A Method Comparison Study Clin Chem 50 166 174 2004 The IFCC Reference Measurement System for HbAlc A 6 Year Progress Report Clin Chem 54 240 248 2008 37 233 241 1994 1480 TEL 0120 103 400 8 30 18 00 8 30 12 00 57 1480 C717 0016E
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