シェアードリサーチ社企業分析レポート - 3D MATRIX [medical technology]
Contents
1.2. 2014 9 9 TDM
3. 3 II 1 2 II 3 1
4. DDS Exploit Technologies Pte Ltd A STAR 2014 5
5. y 5558104 3 D Matrix Inc 2014 6 17 7
6. KOL Key Opinion Leader www sharedresearch jDp Shared eSeafCh 42 81 R Shared Research Report 71711 gt LAST UPDATE 2015 09 07 2015 4 2015 4 100 107 1 903 1 518
7. i 2015 4 20 2015 4 2015 4 97 51 1 918 1 984 y 1 814 1 884
8. DDS MTA
9. www sharedresearch jDp Shared eseatch 25 81 R Shared Research Report 7 7 77 gt LAST UPDATE 2015 09 07 TDM 641 A 0
10. TDM 621 50 300 7 000
11. OS DOF RE EG UT A RN Pe www sharedresearch jDp Shared eseatche 60 81 R Shared Research Report a 1111 gt LAST UPDATE 2015 09 07 16 4 6 779 PP 2016 4
12. 2015 4 es TDM 641 TDM 641 2014 ei 2015 2 17 PMDA
13. PP NM 33 Www sharedresearch jp Shared eseatch 38 81 R Shared Research Report 71711 gt LAST UPDATE 2015 09 07 170
14. 2015 7 6 2015 6 12 2015 4 3 amp www sharedresearch jDp Shared eSeafCh 06 81 R Shared Research Report a 4 71711 gt LAST UPDATE 2015 09 07 15 4 16 4 16 4 20 ci 6 ce 4Q9 0 0 0 100 47 783 2 877 6 96 8 685 7 141 281 181 214 167 3 7 106 1 24 7 24 8 18 1 297
15. PP 2015 4 100 107 1 903 1 518 1 795 1 524 1 995 1 525 2016 4 783 lt 2 877 100 1 996 24 1 903 2 004 16 1 795 2 005 11 1 995 2018 4 9 851
16. 2016 4 C 2016 4 3 2015 6
17. Phase 2 Phase 2011 5 RPN2 A6K DDS siRNA siRNA 2015 4 DDS A6K DDS
18. 1992 MIT Shuguang Zhang R A D 3 RADA 16 pH a ADME 30
19. C 1987 1 zeUUB 1 30 e008 1 14 5 1 2009 11 30 2010 1 2007 12 16
20. 2014 8 8 160 1 2014 7 9 1 2 526 2014 4 2014 6 12 2014 4 ME TDM 621 107 234 7
21. RADA16 4 9 _ 3 4 Il see 3 ry A A A A EO 10 1
22. ASEAN 2 3 CE 1 3
23. 1009 60 70 www sharedresearch jDp Shared eSeafch 36 81 R Shared Research Report a 4 71711 gt LAST UPDATE 2015 09 07 MIT SR
24. www sharedresearch jDp Shared eseatche 67 81 R Shared Research Report 711 gt LAST UPDATE 2015 09 07 2012 2 20 2014 9 3 PuraStat 3 DMatrix Asia Pte Ltd PuraStat 2014 9 3 2014 1 14 PuraStat CE CE CE
25. 2015 4 2016 4 PP 2017 4 2015 4
26. 2015 4 1 160 2015 4 2016 4 2014 7 2014 7 18 TDM 621 Co 3 D Matrix Asia Pte Ltd PT Teguhsindo Lestaritama 2014 7 18 TDM 621
27. Quality of Life QOL PuraStat TDM 621 TDM 621 2014 12 22
28. www sharedresearch jDp Shared eSeafCh 12 81 R Shared Research Report 4 777 7 gt LAST UPDATE 2015 09 07 IE 15 4 16 4 17 4 18 4 Pc E 100 783 2 877 8 233 9 851 816 1 024 1 544 1 643 1 185 1 903 1 996 24 2 180 3 010 1 795 2 004 16 2 180 3 010 1 995 2 005 11 2 064 2 337 SR 15 4 16 4 17 4 18 4 54 758 2 850 7 473 9 091 3 582 675 3 976 9 090
29. et ne 3 2016 4 3 2016 4 2 877 2 094 1 024 208 25 5 CE
30. TDM 812 TDM 812 2015 6 30 1
31. NEDO 2010 www sharedresearch jDp Shared eSeafCh 09 81 R Shared Research Report a 4 777 7 gt LAST UPDATE 2015 09 07 2016 4 16 4 15 4 16 4 6 PlcB 783 2 877
32. 3 4 5 5
33. DIC TOKAL VOYAGE GROUP
34. www sharedresearch jD Shared seareh 13 81 R Shared Research Report 777 7 gt LAST UPDATE 2015 09 07 3 497 70 300 751 gt 2018 4 CE
35. PuraMatrix Corning Incorporated www sharedresearch jDp Shared eSeafCh 19 81 R Shared Research Report 777 gt LAST UPDATE 2015 09 07 TDM 621 a _ EE t
36. 2014 6 4 TDM 621 So 3 D Matrix Asia Pte Ltd TDM 621 2014 6 3 CE Health Sciences Authority www sharedresearch jDp Shared eseatche 72 81 R Shared Research Report 777 7 gt LAST UPDATE 2015 09 07 3 D Matrix Asia Pte Ltd
37. PuraStat CE PuraStat 3 D Matrix Asia Pte Ltd 2014 6 7 9 9
38. TDM 511 www sharedresearch jDp Shared eseatrch e 28 81 R Shared Research Report 711 gt LAST UPDATE 2015 09 07 1 2 2014 10 FDA
39. DDS MIT MIT PuraMatrix www sharedresearch jDp Shared eSeafCh 16 81 R Shared Research Report 777 7 gt LAST UPDATE 2015 09 07 PuraMatrix A 9 9 9 PS LE EC et RARE re AYAZAY2YA nA 2 a 5 Ac R A D A R A D A R A D A R A D A CONH R A D
40. 10 Daewoong Pharmaceutical Co LTD Excelsior Medical Co Ltd PT Teguhsindo Lestaritama Daewoong Pharmaceutical Co LTD Excelsior Medical Co Ltd 2015 6 2016 4 Pk
41. DDS 582 675 176 2 175 CE Nd 582 gt 675 266 316 409 ie
42. pH bFGF PDGF PuraMatrix R A D 16 RADA16 www sharedresearch jDp Shared eseatche 79 81 R Shared Research Report
43. 1 000 ASEAN 2014 3 2013 6 13 10 8 07 BBH For Oppenheimer Global Opportunities Fund 4 20 2 99 SBI 2 69 1 87 CBHK KOREA SECURITIES DEPOSITORY DAISHIN 1 49 CYPRESS JAPAN 1 49 PERSHING DIV OF DLJ SECS CORP 1 41 1 16 MLPFS CUSTODY ACCOUNT 0 94 SR 2015 4 30
44. TDM 711 2012 2 15 FDA TDM 641 www sharedresearch jDp Shared eSeafCh 50 81 R Shared Research Report 4 777 7 gt LAST UPDATE 2015 09 07 10 4 11 4 12 4 13 4 14 4 15 4 402 158 1 107 32 107 100 60 6 599 596 97 1 234 796 6 99 2 8 7 0 6 3 400 150 1 100 32 101 96 1 2 3 0 3 2 46 641 53 1 031 1 626 2 003 111 233 251 395 599 816 355 406 499
45. Www sharedresearch jp Shared eSeafCh 77 81 R Shared Research Report 71711 gt LAST UPDATE 2015 09 07
46. 1 RPN 2 A6K siRNA DDS www sharedresearch jDp Shared eseatche 08 81 R Shared Research Report 711 gt LAST UPDATE 2015 09 07 1 siRNA TDM 812 RPN2siRNA A6K
47. 18 20 31 32 35 2 0 36 SW Strengths Weaknesses 38
48. 2012 2 Se TDM 631 RADA16 TDM 631 www sharedresearch jDp Shared eseatche 26 81 R Shared Research Report 4 71711 gt LAST UPDATE 2015 09 07
49. TDM 621 RADA16 TDM 621 TDM 621 TDM 621 pH gt TDM 68 1 TDM 62 1 TDM 621
50. Wi 2015 3 2015 3 2015 3 13 TDM 621 TDM 621 A Www sharedresearch jp Shared eseatrche 59 81 R Shared Research Report 777 7 gt LAST UPDATE 2015 09 07 6
51. TDM 621 TDM 621 TDM 621 www sharedresearch jD 22 81 R
52. ii Bee nai 2015 4 www sharedresearch jDp Shared eseatche 62 81 R Shared Research Report 71711 gt LAST UPDATE 2015 09 07 2015 1 2015 1 29 PuraStat Fe Daewoong Pharmaceutical Co Ltd PuraStaf
53. www sharedresearch jDp Shared eSeafCh 18 81 R Shared Research Report 1111 gt LAST UPDATE 2015 09 07 aw i ono Pe sas PP 11 2 3 4 PMDA FDA
54. 4 MBA 1999 JASDAQ 7774 2002 2370 COO 2003 10 2005 2007 1998
55. Scaffold GLP Good Laboratory Practice pH w
56. 100 y 3 D Matrix EMEA www sharedresearch jDp Shared eseatche 57 81 R Shared Research Report 71711 gt LAST UPDATE 2015 09 07 300 000 2015 4 2015 4 22 Pe 7
57. 2 3 2014 5 12 3 D Matrix Asia Pte Ltd 3DMA A STAR Exploit Technologies PTE LTD ETPL A STR Institute of Bioengineering and Nanotechnology
58. R Arg ADME ADME Absorption Distribution Metabolism Excretion ADME siRNA 21 23 RNA siRNA RNA RNAi RNA mRNA siRNA MTA Material Transfer Agreement
59. Clinica Las Condes Hospital San Borja Arriaran Cristian Baeza MJD 2014 10 2014 10 23 TDM 511 510 TDM 511 3 D Matrix Inc 2014 10 22 FDA 510 Kl 1 510 0 510 K
60. 39 42 43 43 Sl
61. MIT Shuguang Zhang 2014 11 2014 11 27 ReproHepato PuraMatrix PuraMatrix iPS ReproHepato W 3 PuraMatrix ReproHepato
62. MIT MIT PP
63. www sharedresearch jDp Shared eseatche 37 81 R Shared Research Report 711 gt LAST UPDATE 2015 09 07 SW Strengths Weaknesses Strengths PP MIT PP
64. TDM 631 TDM 631 TDM 631 TDM 631 X TDM 631 TDM 711
65. 1 2005 2007 2012 7 INSEAD MBA 1996 2006 CSBA 2007 CSBA 2008 JASDAQ 2008 2012 7 2015 4 33 18 40 2 4 6 a
66. 1 078 millennium Fibrin Sealant Gelatin Bioglue 8 PuraStat Tachosil Bioglue Arista AH Others 13 MedMarket Deligence TDM 641 TDM 641
67. RPN 2 A6K siRNA DDS NEDO NEDO 2010 www sharedresearch jDp Shared eseatche 44 81 R Shared Research Report
68. 2014 8 21 3 D Matrix Asia Pte Ltd 1009 p 20 100 2014 8 2014 8 28 PuraStaf 2014 1 14 PuraSta CE www sharedresearch jDp Shared eseatche 68 81 R Shared Research Report 777 7 gt LAST UPDATE 2015 09 07 2014 8 26
69. MIT p 8901084 Massachusetts Institute of Technology 2010 7713923 7713923
70. PuraSta 2014 6 10 PMDA www sharedresearch jDp Shared eseatche 46 81 R Shared Research Report 711711 gt LAST UPDATE 2015 09 07 FDA TDM 711 FDA TDM 641 2014 9 PMDA 10 30
71. 0 TDM 711 3 ti TDM 711 TDM 711 TDM 711
72. CE 2014 7 2015 3 20 53 CE 2014 6 9 2014 7 2015 4 www sharedresearch jDp Shared eseatch 43 81 R Shared Research Report a 777 7 gt LAST UPDATE 2015 09 07 2015 1
73. 75 76 76 CC 77 80 Www sharedresearch jp Shared Gcseareh 02 81 R Shared Research Report a 1111 gt LAST UPDATE 2015 09 07
74. FDA 2014 12 2015 2 3 2015 9 15 FDA 1 2014 10 FDA 510 k 2015 2 510 k
75. CE CE 2013 5 3 D Matrix Asia Pte Ltd PT Tegushindo Lestaritama TDM 711 15 FDA EL TDM 641
76. gt gt gt gt www sharedresearch jDp Shared eSeafCh 17 81 R Shared Research Report 71711 gt LAST UPDATE 2015 09 07 DDS
77. www sharedresearch jDp Shared eSeafCh 27 81 R Shared Research Report 4 1111 gt LAST UPDATE 2015 09 07 0 2 oe RNN www sanramonoralsurgery60m bonegrafting htm 1 TDM 711
78. www sharedresearch jDp Shared eSeafCh 34 81 R Shared Research Report 777 7 gt LAST UPDATE 2015 09 07 upppupsu uwv5W WVW 1505 R 5 y 3 D Matrix Inc 1009 3 D Matrix Europe SAS 100 3 D Matrix EMEA 100 y 3 D Matrix Asia Pte Ltd 100 3 D Matrix Da America Latina Representacao Comercial Ltda 100 100 3 D Matrix LtQ JPN 3 D Matrix AsialPte Ltd SG 3 D Matrix Da America Le Representacao Comercial Ltda BR Www sharedresearch jp Shared eseat
79. 2017 4 2015 3 9 PuraSta ye 3 D Matrix Europe SAS PuraStat CE 2015 3 6 2014 1 14 PuraStatY CE
80. 2012 4 TDM 621 3 D Matrix Europe SAS 2012 10 3 D Matrix Asia Pte Ltd 2013 2 TDM 621 FDA IDE 2013 3 ISO013485 2013 5 PT Teguhsindo Lestaritama TDM 621 2014 1 TDM 621 CE 3 D Matrix Inc 2007 10 3 D Matrix Inc 2009 4 amp 2015 5 27
81. 53 55 56 56 amp 57 75
82. TDM 621 PMDA www sharedresearch jDp Shared eseatche 49 81 R Shared Research Report 71711 gt LAST UPDATE 2015 09 07 ISO13485 TDM 621 FDA IDE Investigational Device Exemption CE EU EU CE
83. 2014 PuraMatri ReproHepato PuraMatri 3 ReproHepato PuraMatri 2014 11 6 PuraStat 2014 1 14 PuraSta CE www sharedresearch jDp Shared eseatche 65 81 R Shared Research Report a 7 7 77
84. CRO MM 1 2 3 TDM 621 2009 2015 4 5
85. PP 2014 9 2015 4 2015 1 2015 6 2015 3 2016 4 TDM 641 2014 12 2015 3 TDM 631 2016 4 2017 4 2018 4 www Ssharedresearch jDp Shared eSeafCh 14 81 R Shared Research Report 777 7
86. ai 3 976 55 CE CE PMDA CRO 2 3 2017 4
87. 3 2014 1 2014 1 31 3 D Matrix Inc MIT B Bridge International B Bridge 3 D Matrix Inc www sharedresearch jDp Shared eseatche 74 81 R Shared Research Report 4 711 gt LAST UPDATE 2015 09 07 PanaceaGel w
88. 3 000 CE CE www sharedresearch jDp Shared eSeafCh 24 81 R Shared Research Report 7 7 77 gt LAST UPDATE 2015 09 07 M 3 500 USD3 000M 000 1 EE2 CE LT 2 500 266 TTP CE CE 2 000 1078 1 085 185 94 1 500 86 80 ee ee 1 000 500 0 14 000 1cc SR
89. EU 28 2014 6 3 CE Health Sciences Authority 3 D Matrix Asia Pte Ltd CE PuraStat 2014 9 1
90. TDM 641 www sharedresearch jDp Shared eseatch 31 81 R Shared Research Report 7 7 7 gt LAST UPDATE 2015 09 07 2 100 MTA
91. 2004 5 LR 1992 MIT Shuguang Zhang MIT MIT 2001 5 3 D Matrix Inc 2004 5 2004 10 3 DMatrixInc LICENSE AND SUPPLY AGREEMENT 3 D Matrix Inc MIT MIT Scientific Founders
92. 97 2011 4 TDM 621 5 7 2011 5 PMDA TDM 621 PMDA 2015 3 TDM 621 2016 4
93. PP 5 PMDA FDA 65 2 3 7 TDM 621 TDM 711 TDM 641 TDM 631 TDM 511 TDM 621 RADA16 TDM 621 97
94. Shared Research SR Inc SR Inc SR Inc SR Inc SR Inc SR
95. www sharedresearch jDp Shared eseatche 71 81 R Shared Research Report 711 gt LAST UPDATE 2015 09 07 3 D Matrix Da America Latina Representacao Comercial Ltda 600 000 27 2014 6 13 99 3 D Matrix Europe SAS 19 2014 6 5
96. PuraStat A 3 D Matrix Asia Pte Ltd PT Teguhsindo Lestaritama 2015 4 16 Ministry of Health PuraStat 2014 1 14 PuraStaY CE CE CE a EU 28 2014 7 18 CE
97. 1 024 1 996 24 2 004 16 2 005 11 SR 16 4 15 4 16 4 54 758 2 850 3 582 675 51 176 2 175 45 25 gm 0 7 45 18 SR 7 83 2 877 100 1 996 24 1 903 2 004 16 1 795 2 005 11 1 995
98. 3 2011 5 31 PMDA PMDA 2015 3 2016 4 2015 4 2015 4 51 10 418 1 984
99. 2010 9 17 Daewoong Pharmaceutical Co LTD PARTNERSHIP AGREEMENT Excelsior Medical Co Ltd LICENSE AGREEMENT 2013 5 29 3 D Matrix Asia Pte Ltd PT Teguhsindo Lestaritama 2015 1 2014 7 CE 2014 7 9 www sharedresearch jDp Shared eseatche 23 81 R Shared Research Report 777 7 gt LAST UPDATE 2015 09 07 9 2017 4
100. 1 626 57 6 599 51 5 1 024 61 0 1 518 999 1 523 977 1 525 978 www sharedresearch jDp Shared eseatche 48 81 R Shared Research Report 7 7 77 gt LAST UPDATE 2015 09 07 TDM 621 PMDA FDA 2014 1 14 CE EU
101. CE TDM 621 2014 5 2014 5 30 3 2014 2
102. 2014 2 2014 2 13 3 2
103. Heart and Diabetes Center NRW Clinic for Thoracic and Cardiovascular Surgery Michiel Morshuis MD 5 000 2014 8 8 2014 8 8
104. TDM 621 2015 2 2014 6 12 2014 12 11 TDM 641 MIT TDM 641 TDM 641
105. Aiming SBS KLab J GCA
106. 2014 6 3 2 CE Ministry of Health 2015 4 2014 7 1 4 PuraSta 2014 1 14 PuraStat CE www sharedresearch jDp Shared eseatche 69 81 R Shared Research Report 777 7 gt LAST UPDATE 2015 09 07 2014 7 1 St John of God Hospital St John of God Hospital Department of Surgery Bernhard DAUSER M D
107. 582 675 176 2 175 25 316 409 266 2016 4 www sharedresearch jD Shared seareh 10 81 R Shared Research Report 71711 gt LAST UPDATE 2015 09 07
108. 2015 3 PMDA 2016 4 2014 1 CE CE 2014 8 4 2015 4
109. 43 25 2015 3 PMDA 1 PMDA 2 2014 1 CE www sharedresearch jDp Shared eSeafCh 07 81
110. EU 2018 4 751 08 TDM 621 2014 1 14 CE 2015 4 2016 4 PP 2015 3
111. 122 482 2010 4 65 510 60 534 61 Www sharedresearch jp Shared eSeafCh 52 81 7777 R Shared Research Report gt LAST UPDATE 2015 09 07 10 4 11 4 12 4 13 4 14 4 15 4 544 589 1 758 2 033 2 641 Sl3Z 52 33 39 25 261 789 777 17 39 718 190 163 290 594 666 2 501 2 484 3 593 6 204 7 6 88 107 103 94 19 22 30 47 86 118 537 467 397 327 257 187 42 38 40 46 56 136 578 505 437 383 339 393 604 533 554 536 528 605 1 198 1 199 3 055 3 020 4 121 6 809 12 16 22 48 92 139 4 24 30 43 37 33 g 15 9 59 821 829 238 31 49 112 913 958 409
112. CE 8 0 2014 5 31 19 914 800 6 283 3 000 2018 4 WM 800 2015 4 2017 4 2 800 2014 8 2018 4 www sharedresearch jDp Shared eseatche 70 81 R Shared Research Report 711 gt LAST UPDATE 2015 09 07 200 2014 11 2016 4 y 800 2015 4
113. 6 058 6 000 S11 1 4 180 6 3 174 2 173 0 169 2 171 0 171 3 170 7 07 08 09 10 11 12 13 14 5 000 4 000 3 000 Ll 2006 2007 2008 2009 6 2016 1 344 iDATA Research 2016 1 078 millennium 30 509 www sharedresearch jDp eShat esearch 39 81 R Shared Research Report 1111 gt LAST UPDATE
114. 2 B Bridge 3 D Matrix Inc PanaceaGel 3 D Matrix Inc MIT 3 D Matrix Inc Shuguang Zhang 2014 1 15 TDM 621 CE NM D Matrix Europe SAS TDM 621 CE 2014 1 14 EU 0 MA E
115. 1 600 000 2014 6 24 2014 6 26 0 90 1 00 Mizuho International Plc 2014 7 9 2014 6 20
116. 2016 4 PuraStat 2016 4 2015 7 10 Daewoong Pharmaceutical PuraStat ASEAN 3 D Matrix Asia Pte Ltd 3DMA Daewoong Pharmaceutical Co Ltd DW PuraStaY ASEAN 2015 7 10 3DMA DW PuraSta DW ASEAN
117. 2015 2 2016 4 3 2015 6 1st Pilot Study 15 2nd Pilot Study FDA 2016 4 2014 10 FDA 510 k 2015 2 510 k 2015 6
118. PMDA 2016 4 2016 4 EU 2016 4 3 100 2015 6
119. 2016 4 PT i Lestaritama PT Teguhsindo Lestaritama 50 FM 2015 4 NMOS PL CU 2015 4 15 0 TDM 511 a
120. PP SR Weaknesses PP A MIT MIT 2014
121. GLP TDM 711 2010 9 FDA IDE 2011 7 IDE 2012 2 Forsyth Institute 1st Pilot Study 2012 6 15 2014 5 FDA 2015 2nd Pilot Study TDM 511 TDM 511
122. PMA 90 FDA 510 FDA 90 FDA Www sharedresearch jp Shared eseatche 66 81 R Shared Research Report 71711
123. gt LAST UPDATE 2015 09 07 TDM 711 2012 2 2017 4 2018 4 TDM 511 2014 10 FDA 510 k 2015 2 510 k 510 k www sharedresearch jDp Shared eSeafCh 15 81 R Shared Research Report 71711 gt LAST UPDATE 2015 09 07 Massachusetts Institute of Technology MIT
124. DDS 2014 12 2014 12 22 PuraStaf 2014 1 14 PuraStat CE 2014 12 27 2014 12 22 www sharedresearch jDp Shared eseatche 63 81 R Shared Research Report 1711 gt LAST UPDATE 2015 09 07 Edouard Herriot Hospital Hepato Gastroenterology Department Thierry Ponchon 900
125. TDM 641 ove LILUTTLILTIL TTT TTI TDM 641 TDM 621 RADA16 TDM 621 TDM 641 2014 9 PMDA 2014 12 EMR ESD 260 2015 3
126. www sharedresearch jD 04 81 R Shared Research Report 1111 gt LAST UPDATE 2015 09 07 2015 9 7 2016 4 1 2016 4 1 2015 7 23 PuraStat 7 3 D Matrix Europe SAS 2015 7 23 INVIMA PuraSta 2015 3 6 CE
127. MIT 3 D Matrix Inc MIT SR 2014 www sharedresearch jD 33 81 R Shared Research Report 71711 gt LAST UPDATE 2015 09 07 MIT MIT MIT 2001 5 3 D Matrix Inc
128. 1 4471 www sharedresearch jDp Shatred eSeafch 41 81 R Shared Research Report 711 gt LAST UPDATE 2015 09 07 SR
129. 510 k 2015 1 510 k 510k 510 k DDS DDS DDS bFGF PDGF A6K siRNA
130. TDM 621 2014 6 www sharedresearch jDp Shared eseatche 47 81 R Shared Research Report 1111 gt LAST UPDATE 2015 09 07 PMDA FDA TDM 711 FDA TDM 641 2014 9 PMDA 2015 3 2 3 TDM 511 FDA 510 k
131. 71711 gt LAST UPDATE 2015 09 07 2015 4 3 2015 4 3 0 56 1 514 1 049 1 423 1 058 1 588 1 059 603 40 9 911 35 0 3 131 1 3 5 2 54 8 3 72 7
132. Www sharedresearch jp Shared eSeafCh 76 81 R Shared Research Report 777 7 gt LAST UPDATE 2015 09 07 Investigational Device Exemption FDA D D Asp COOH NH2 A A Ala R
133. PMDA TDM 511 2014 10 FDA 510 k 2015 4 1 2014 9 12 2015 4 1 2015 4 1 0 48 438 321 471 341 635 341 1 a 2015 3 TDM 621 a TDM 621 2014 1
134. 948 2011 8 1 4 3 792 2012 9 1 2 9 222 2013 6 1 2 18 936 www sharedresearch jD 54 81 R Shared Research Report gt 2014 4 1 064 19 876 5 4 7777 LAST UPDATE 2015 09 07 2014 4 10 4 11 4 12 4 1 28 434 131 2 13 18 100 FCF 1 2 40 452 231 498 1 400 A 75
135. 0 55 42 29 18 0 55 42 29 18 31 49 167 955 988 428 1 109 1 359 2 070 2 139 3 339 5 930 1 099 1 349 2 060 2 129 3 329 5 920 1 063 1 596 1 288 2 266 3 792 5 9 11 19 34 228 341 1 167 1 150 2 888 2 066 3 133 6 382 21 22 213 69 690 544 569 1 758 2 033 2 641 353 SR 2015 4 750 2015 4 777 11 2015 4 187 3 D Matrix Inc 70 2019 4
136. 24 6 9 10 2014 4 1 www sharedresearch jDp Shared eseatche 75 81 R Shared Research Report a 71711 gt LAST UPDATE 2015 09 07 3 D Matrix Inc 2004 3 D Matrix Inc gt 2000
137. gt LAST UPDATE 2015 09 07 2014 9 2014 9 10
138. HD SR Inc SR Inc
139. 1111 gt LAST UPDATE 2015 09 07 2 000 5 6 1 800 1 600 5 P 1 400 Proprietary 1 200 7 9 Nonproprietary py 800 28 600 4 400 14 6 200 Millennium Research Group US Market for Dental Biomaterials 0 2010 2008 2009 2010 2011 2012 2013 2014 MIT CSL amp
140. 354 3 14 26 48 310 309 2012 4 300 www Ssharedresearch jDp Shared eseatche 51 81 R Shared Research Report 71711 gt LAST UPDATE 2015 09 07 2011 4 158 2010 4 402 150 2010 4 400 641 2010 4 174 50 TDM 621
141. 4 000 2014 6 2014 6 25 1270 000 1 600 000 21 184 800 21 514 800 5 016 6 283 4 84 4 77 gt 1 4 162 p 5 286 1 3 977 5 5 051 2014 6 24
142. FDA TDM 711 FDA www sharedresearch jDp Shared eseatrche 45 81 R Shared Research Report 777 7 gt LAST UPDATE 2015 09 07 TDM 641 2014 12 TDM 511 2014 10 FDA 510 kk 2015 2 510 k 2015 4 2 2015 4 2 0 49
143. 2013 4 FDA IDE Investigational Device Exemption 2016 4 2017 4 2014 1 CE ii EU CE CE ENE OR Oe CE TDM 621 2011 5 1 4538
144. 2014 9 9 PMDA PMDA 2014 12 11 EMR ESD 7 PMDA TDM 641 www sharedresearch jDp Shared eseatche 64 81 R Shared Research Report 71711 gt LAST UPDATE 2015 09 07 2014 12 3
145. www sharedresearch jDp Shared eseatche 11 81 R Shared Research Report 711711 gt LAST UPDATE 2015 09 07 ive a 0
146. 1 2 3 3 TO 1 2013 4 2015 4 TDM 621
147. Germany France UK EU Italy Spain witzrland IStFIa Hong Kong CE Chile New Zealand Singapore Indonesia Korea Taiwan gt Australia Brazil Mexico Columbia CE US J pan TDM 711 ei 3 EU TDM 641 TDM 511 TDM 641 Japan TDM 631 TDM 711 US TDM 511 www sharedresearch jDp Shared eseatch 20 81 R Shared Research Report 4 777 7 gt LAST UPDATE 2015 09 07 2015 6
148. MIT www sharedresearch jDp Shared eSeafCh 32 81 R Shared Research Report 4 71711 gt LAST UPDATE 2015 09 07 US 5670483 1997 9 23 2014 11 29 i r lt 4 a i US 6548630 MIT 2003 4 15 2017 7 21 2008 316133 US 5955343 1999 9 21 2014 8 21 PuraMatrix buraMatri US 6800481 MIT 2004 10 5 2017 3 25 uraMatrix P Matri pps a go US 744918
149. gt LAST UPDATE 2015 09 07 PuraMatrix B 2014 4 2014 4 1 Pe TDM 511 2014 4
150. 1 4502 2009 Medmarket Diligence 1 4503 1 3401 CSL 1 4559 AH 1 4543
151. Informed Consent 2 3 TDM 621 MY ha PEE pH
152. PMDA RPN 2 2011 Phase NEDO 2010 2013 4 2013 6 13 2013 4 32 977 978 2013 4 19
153. 2015 6 CE 2015 3 Ce FDA 2016 4 2014 12 7 2 1 50
154. CE CE EU 28 3 D Matrix Da America Latina Representacao Comercial Ltda www Ssharedresearch jDp sShared eSeafCh 61 81 R Shared Research Report 71711 gt LAST UPDATE 2015 09 07 2015 2 2015 2 16 TDM 511 510 k TDM 511 3 D Matrix Inc 2014 10 23 FDA 51
155. TDM 621 2014 1 CE CE 2014 KOL key opinion leader TDM 621 2015 3 60 PuraStaY CE PuraStat 3 D Matrix Asia Pte Ltd 2014 6 7
156. 2015 1 29 CE 2014 1 14 PuraStatY CE CE CE EU 28 CE PuraStaf 2015 1 27 MIT 3 D Matrix Asia Pte Ltd MIT
157. RPN2siRNA A6K RPN2siRNA 2012 3 RNA DDS www sharedresearch jDp Shared eseatche 29 81 7777 R Shared Research Report gt LAST UPDATE 2015 09 07 DDS siRNA www sharedresearch jDp Shared e
158. Massachusetts Institute of Technology MIT 4 MIT MIT PP
159. 3 010 3 010 2 337 SR 3 MIT 3 SW Strengths Weaknesses www sharedresearch jDp Shared eseatch 03 81 R Shared Research Report gt 7777 LAST UPDATE 2015 09 07 10 4 11 4 12 4 13 4 14 4 15 4 158 60 6 641 37 2 482 1 107 599 5 753 17 5 354 32 0
160. 7 7 2016 4 10 13 16 16
161. 2007 10 3 D Matrix Inc 1992 MIT Shuguang Zhang 2001 5 MIT 3 D Matrix Inc 2003 4 3 D MatrixInc MIT Exclusive Patent License Agreement 2004 5 2004 10 3 D Matrix Inc LICENSE AND SUPPLY AGREEMENT 3 D Matrix Inc PuraMatrix 2007 10 3 D Matrix Inc 2008
162. 1 795 1 524 1 995 1 525 Mo ye 3 51 816 36 3 1 185 15 8 141 1 3 5 2 54 8 3 72 7 4 10 0 PMDA
163. DW PT Teguhsindo Lestaritama 2 4 ASEAN DW PuraStat www sharedresearch jDp Shared eSeafCh 05 81 R Shared Research Report a 71711 gt LAST UPDATE 2015 09 07 CE 2016 4 2017 4 2016 4 1 30 2015 7 7 siRNA TDM 812
164. 71711 gt LAST UPDATE 2015 09 07 2 5 eNO 3 2 4 HF 7 03 3511 3440 2004 5 19 2011 10 24 HP http www 3d
165. IBN Dr Charlotte Hauser ETPL 3DMA 6 o B www sharedresearch jDp Shared eseatrche 73 81 R Shared Research Report 711
166. 9 9 i PuraSta 2014 6 10 2011 5 31 PMDA PR 2015 3 13 2015 3 2016 4
167. 51 176 2 175 3 497 1 45 25 758 758 0 7 45 18 751 751 SR 2016 4 2017 4 TDM 621 PR 2017 4 CE
168. CN MIT MIT 3 D Matrix Inc 2003 4 MIT Exclusive Patent License Agreement MIT fe 2004 10 3 D Matrix Inc License and Supply Agreement 3 D MatrixInc 2007 10 3 D MatrixInc 3 D Matrix Inc
169. R Shared Research Report a 71711 gt LAST UPDATE 2015 09 07 1 1 3 amn 3 CE 1 Daewoong Pharmaceutical Co Ltd ASEAN
170. 1 004 676 984 701 1 148 701 422 49 2 583 31 5 2 58 4 1 3 5 2 54 8 TDM 621 2014 1 CE CE
171. 2 Becton Dickinson and Company SUPPLY AGREEMENT PuraMatrix RADA16 2008 3 2008 10 TDM 621 2009 4 2009 7 TDM 621 2009 8 TDM 621 J Www sharedresearch jp PMDA Shared 8 esearch 56 81 R Shared Research Report 111 gt LAST UPDATE 2015 09 07 2010 1 TDM 621
172. 2015 09 07 2016 1 344M cifi ipaTA 1 600 M 1 400 1 200 1 000 800 600 400 200 CY06 CYO7 CY08 CYO9 CY10E CY11E CY12E CY13E CY14E CY15E CY16E 2016 1 078M 1200 M 2010 2016 1 000 800 600 400 200 CY10 CY11 CY12 CY13 CY14 CY15 CY16 80 10 113 685 11 526 60 10 5 6 Millennium Research Group www sharedresearch jDp Sharedd eSeafch 40 81 R Shared Research Report
173. 2 009 2 080 IN PuraStat Ne Teguhsindo Lestaritama 50 PuraStat 3 13 2015 3 13 2016 4 www sharedresearch jDp Shared eSeafCh 58 81 R Shared Research Report 71711 gt LAST UPDATE 2015 09 07 2015 4 16
174. 200 400 2010 9 300 600 Excelsior Medical Co Ltd Daewoong Pharmaceutical Co LTD 2011 10 1 352 700 2013 7 2 289 550 2014 7 5 051 1 270 1 10 4 11 4 12 4 13 4 14 4 15 4 8 9 4 589 9 468 19 876 21 438 EPS 6 1 56 696 74 105 78 95 EPS 69 DPS BPS 137 634 2 120 159 5 625 1 107 3 146 2 281 8 13 568 15 168 18 355 18 936 19 876 21 438 EPS 4 5 18 5J 78 95 EPS 17 DPS 8 BPS 86 0 5 1 156 3 3 146 2 281 8 SR 2011 7 1 100
175. 2010 8 13B1X10105 2010 9 3 D Matrix Inc TDM 711 IDE FDA Daewoong Pharmaceutical Co LTD PARTNERSHIP AGREEMENT TDM 621 Excelsior Medical Co Ltd LICENSE AGREEMENT TDM 621 2011 5 TDM 621 TDM 621 PMDA TDM 621 PMDA 2011 7 3 D Matrix Inc TDM 711 FDA IDE 2012 2 TDM 641 TDM 711 2012 3
176. 310 107 234 796 1 626 57 696 1 518 783 2 877 1 996 24 2 004 16 2 005 11 EPS EPS DPS BPS jr 13 568 4 5 578 1 198 15 168 22 75 1 1 199 18 355 18 4 17 3 156 3 1 758 2 501 88 30 437 59 2 033 2 484 107 146 2 2 641 3 593 103 922 056 26 434 131 64 1 680 1 905 18 100 56 83 126 451 498 1 400 983 2 360 4 511 ROA 6 3 44 6 14 596 32 290 42 79 36 590 ROE 6 6 46 3 15 4 39 990 61 8 44 0 97 4 95 0 CS 67 3 70 5 90 4 SR
177. CE CE TDM 621 CE TDM 621 3 D Matrix Asia Pte Ltd 2014 6 2014 9 3 2014 7
178. Inc Shared Research inc 3 31 12 http www sharedresearch jp TEL 03 5834 8787 Email Info sharedresearchJp Shared WSeseafcH 81 81 www sharedresearch jDp
179. gt LAST UPDATE 2015 09 07 2014 10 30 Pamela Youde Nethersole Eastern Hospital PYNEH 11 6 Chung Ngai TANG M D Chief of Service Department of Surgery and Director of Minimal Access Surgery Training Centre of PYNEH PYNE 5 000 2014 11 4 PuraSta 7 2014 1 14 PuraStatY CE 2014 10 30 Hospital San Borja Arriaran
180. 0 2008 1 2009 3 Www sharedresearch jp Shared eSeafCh 21 81 R Shared Research Report 4 1711 gt LAST UPDATE 2015 09 07 TDM 621 TDM 621 1
181. 0 2008 11 30 2021 2 5 PuraMatrix MT EP 717398 2008 12 31 2022 2 5 PuraMatrix Is PEICP 1 2024 6 24 PuraMatr mezeztee T huraMatr PuraMatrkx PuraMatr C HH 5263756 1 2013 5 28 US 8647867 PH PuraMatrix EE 5497451 2014 4 1 SR PCT 3 D Matrix Inc MIT AMENDED AND RESTATED EXCLUSIVE PATENT LICENSE AGREEMENT FIRST AMENDMENT SECOND AMENDMENT THIRD AMENDMENT TO AMENDED AND RESTATED EXCLUSIVE PATENT LICENSE
182. 0 k 2015 2 13 TDM 511 510 k Rx Prescription OTC Over The Counter
183. 286 328 274 354 33 696 29 3 41 7 21 596 19 0 438 567 509 389 519 1996 24 5 471 514 438 372 477 2004 16 _ 635 514 439 407 453 2005 11 5 SR 2016 4 1 2016 4 1 47 0 519 438 477 471 453 635 167 18 1 354 19 0
184. 4 483 1 884 4 466 2 080 3 654 3 PP 2015 3 13 PTAM 2015 3
185. 636 1 024 1 185 65 482 354 999 1 518 1 903 E 6 i 32 0 11 0 38 32 153 0 0 0 0 1 3 1 34 27 141 5 i 2 2 4 4 5 27 48 17 38 45 0 8 12 8 s 6 6 6 4 2 2 14 1 16 32 60 510 310 978 1 524 1 795 E a 28 0 8 3 8 1 21 1 1 2 5 61 534 309 978 1 525 1 995 E 6 5 i i 27 9 i SR 2012 4 1 107 1 TDM 621 2 TDM 641 3 753
186. 641 TDM 641 2014 9 9 PMDA TDM 641 3 C TDM 641
187. 79 79 B 10 90 C 1 20 FCF NI A B C 467 318 SR Shared 8 esearch Www sharedresearch jp 13 4 14 4 647 1 680 56 83 703 1 763 983 2 360 86 102 36 40 210 485 1 139 1 948 2005 126 2 030 4 511 53 82 2 017 55 81 7777 R Shared Research Report gt LAST UPDATE 2015 09 07 Massachusetts Institute of Technology MIT Shuguang Zhang
188. LAST UPDATE 2015 09 07 7777 Research Report by Shared Research Inc sr_inquiries sharedresearch jp ohared 4 esearch R Shared Research Report a GT 71711 LAST UPDATE 2015 09 07 RY
189. SeafCh 30 81 R Shared Research Report 4 71711 gt LAST UPDATE 2015 09 07 CPC Scientific Inc 3 3 TDM 621 2011 5 2009 4 1 8001 o Daewoong Pharmaceutical Co LTD Excelsior Medical Co Ltd PT Teguhsindo Lestaritama
190. Shared esearche 53 81 Www sharedresearch jp R Shared Research Report 4 711 gt LAST UPDATE 2015 09 07 2007 10 579 1 448 3DM Investmen LLC Massachusetts Institute of Technology 2009 11 500 1 250 4 JAIC TAIB JAIC Asian Balanced Private Equity Fund 2010 9
191. Shared Research Report 1111 gt LAST UPDATE 2015 09 07 TDM 621 Informed Consent 2 2 i TDM 621 2010 1
192. ch 35 81 R Shared Research Report 7 7 77 gt LAST UPDATE 2015 09 07 FN MIT EE Rt TT TT N em 1 Wi
193. matrix co jp index html 4 IR IR http www 3d matrix CO jD ir index html www sharedresearch jDp Shared eseatch 80 81 R Shared Research Report SR MG
194. ww sharedresearch jDp Shared eseatche 78 81 R Shared Research Report 777 7 gt LAST UPDATE 2015 09 07 DDS Drug Delivery System
Download Pdf Manuals
Related Search