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Nucleic Acid Purification System NPA
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1. No Phenomenon Reason analysis Troubleshooting Disconnected power Check power supply for supply correct connection Replace it F 250V 3A 5 Bad fuse 4 No display after x 20 power on f Switch failure Replace it Others Contact distributor or manufacturer Beeps after power on and the screen gt displays Self testing error Contact distributor or manufacturer system error Beeps during file running and the screen displays Moving part is out of Run the file again 3 Osio limit Contact distributor or Bad contact of chip g Abnormal characters with its socket Contact distributor or displayed DM manufacturer Chip malfunctioning ace keve Switch of touch panel Contact distributor or y destroyed manufacturer Note During warranty terms the user is forbidden to open the instrument to check Please contact distributor or manufacturer if there is a need to open the device to check a failure listed in the above table 21 Annex1 Wiring Diagram The Bioer Co reserves the right to modify this Wiring Diagram at any time without notice INPUT AC100 240V ene 5
2. Position 1 2 3 4 5 6 Time Second m Maanetic stick running Tip running User s Manual BIOER Nucleic Acid Purification System 7 4 Click pop up menu from Location Column to choose the action s location Ris Ribose Untitled File E File E Edit E View V Help H CO as a Bee 5 2 23 X P O CF First Hole Second Hole Third Hole Fourth Hole fifth Hole Sixth Hole Position Magnetic stick running 7 5 Click Time Second Column and input the detention time of action EA AUTE File F File F Edit E View w Help H C D a Bl 33 8 amp 2 XC Go P 9 amp gt First Hole Second Hole Third Hole Fourth Hole fifth Hole Tipl Sixth Hole Position 1 Magnetic stick running RAE User 5 Manual Nucleic Acid Purification System BIOER 7 6 Repeat the steps 3 5 and program actions that you need JT Rip Ribose Untitled File E File E Edit E View V Help H C D s E B3 5 8 2 X 60 P com 1 o First Hole Second Hole Third Hole Fourth Hole Fifth Hole Sixth Hole Tip Position 1 2 3 4 5 6 Magnetic stick running Tip running Tip running Magnetic stick running Magnetic stick running Tip runninq Third Hole Fourth Hole Fifth Hole Sixth Hole Position User s Manual Nucleic Acid Purification System BIOER 7 8 E
3. File editing and saving File review modify and delete Pause of program running Stop of program running Sound alarm Failure protection and alarm Note The above software functions are for reference only The Bioer Co reserves the right to modify the software functions without notice User 5 Manual Nucleic Acid Purification System BIOER CHAPTER 3 PREPARATIONS This chapter introduces nucleic acid purification system s mechanical structure the keyboard and each button s functions and some preparations before power on Before any operation please read this chapter carefully and make sure you are familiar with the steps introduced 1 Structure Description User 5 Manual Nucleic Acid Purification System BIOER Dcase body Q display conductive rubber workroom touch panel lid switch socket with fuse Note The fuse specifications are as follows F 250V 3A 25x20 The fuse should be replaced by one that meets those specifications If you need certificated fuses please contact the distributor or manufacturer 2 Touch Panel Diagram 3 Introduction of pressing keys left moving the cursor one position to the left when pressed during file parameter setting right moving the cursor one position to the right when pressed during file parameter setting cursor moving PgUp Select different item when pressed in the menu of system sett
4. The instrument is designed for extracting DNA RNA and mRNA in whole blood sell and tissue which saves a lot of time and labors in laboratory 2 Applications This type of instrument is designed to separate or purify nucleic acid protein and tissue in molecular biological lab or clinical lab User s Manual Nucleic Acid Purification System BIOER CHAPTER 2 SPECIFICATIONS This chapter describes the nucleic acid purification system operation transportation and storage conditions basic parameters performance and functions 1 Normal Working Conditions Ambient temperature 5 C 35 C Relative humidity lt 70 Power supply AC100 240V 100W 50 60Hz Note Before power on please check whether the above working conditions are satisfied Pay special attention to the power line s reliable grounding 2 Transportation and Storage Conditions Ambient temperature 20 C 55 C Relative humidity lt 80 3 Basic Parameters Model Parameter iab Sample Number 32 samples magnetic sticks fixed 4x8 volume 50 8001 Collecting efficiency of gt 90 magnetic beads Suitable size of magnetic bead Psi Dimension mm 440X 380x450 LXWXH Net Weight 25kg User s Manual Nucleic Acid Purification System BIOER 4 Performance Work temperature Room temperature Max motor speed 180rpm Max segments 200 Max dwelling time 59m59s Number of programs 25 5 Software Functions
5. limit switch Perpendicular stalk lift axis p YA2 U9 optocoupler inm YB2 YB1 U8 optocoupler optocoupler HALL Perpendicular base axis U6 YA2 optocoupler U5 u4 U18 x2 Right limit Leve 1 Left limit HALL Level stalk Front panel 23
6. or Select Yes Sedet No and and press press ENTER User s Manual Nucleic Acid Purification System ili to select Select Yes and press Enter to confirm deleting the file e Select No and press Enter to undelete the file and go back to the file checking interface BIOER 1 22 File is being 1 23 deleted It shows the file is being deleted after about five seconds later it will go back to file review interface Note If you want to give up editing press MENU to go back the main menu at any time 4 How to run pause file Firstly enter the main menu press 49 or to move the cursor to File and press ENTER Press or ED to select one existing file which you want to run e g file 19 then pess My or to move the cursor to Run and press Enter Enter the interface of file running This picture means the segment one is in running and remaining time is 1h30m20s MAIN MENU 1 24 FileM New Svs Selecting File and press ENTER File 19 1 25 Runi Edit Enter the interface of running file Seg 001 Running 1 26 RemainTime 01h3 Note When running a file that Move T and Loc 3 4 5 in the segment one while Move P in segment two the system will move T to the location 2 and then perform movement of P 13 User 5 Manual Nucleic Acid Purification System After finishing running a file
7. running Please turn off the power immediately and contact the distributor if an abnormal sound or display appears after power on or if there is a failure alarm and display in the process of self testing Warning Are you ready Let s begin 1 How to edit a new program file Enter the main menu press or to move the cursor to item New then press ENTER key Seg 001 indicates the first segment which is carried out by the system automatically and maximum segments are 99 Press or to move the cursor onto Move item gt Move Set moving parts Press or amp to shift among the four parameters M T P E M shows magnetic stick moving up and down e T shows magnetic stick and Tip moving up and down together e P shows micro plate moving e E shows file edit ends and this is MAIN MENU 1 1 File New Sys File editing interface Move M Select New Press ENTER Key Seg 001 1 2 Loc 0 After setting Move parameters press to enter Loc User 5 Manual Nucleic Acid Purification System BIOER the end segment of a file Loc Settarget position of moving parts Press or to shift among 0 5 Seg 001 Move M 0 shows no moving 1 3 Loc 5 1 shows move to 1 5 position of maximum moving distance 2 shows move to 2 5 position of maximum moving distance ASE setting e Loc 5 shows move to the posit
8. the buzzer will beep Press MENU to go back to the main menu Note Press Start Pause Y during file running the file running will be suspended and timing will also be paused press O again the file continues running and timing will be resumed e Pressing Y to stop the procedure and return to the main menu during file running BIOER 1 27 Operation End 1 28 Please take Seg 001 Running 1 30 RemainTime 02h5 pressing D Pressing again pause running to resume running Seg 001 Pause 1 31 RemainTime 02h50 Seg 001 Running 1 32 RemainTime 02h50 Pressing O to stop file running and return to the main menu 5 Review system default file Enter the main menu and click D or to move the cursor to Sys then click ENTER Enter Default File option then click or ED toreview default file name A F Click MENU to go back to the main menu MAIN MENU 1 33 File New Svs MAIN MENU 1 34 File New Sys Select Sys and press ENTER 1 35 Default File ZA System setting interface User 5 Manual Nucleic Acid Purification System BIOER 6 Protection interface uu Door open protection interface gt Open the door when file is running it appears a Door open protection interface The buzzer will alarm and running will be paused Close the door Running will be resumed Door Open gt During the process
9. to the file number setting interface then set a new serial number e Select Overwrite and press Enter to show the new file is being saved and the original file will be overwritten Note In file number setting interface press UD or to select e While Run press Enter to run file just edited and then enter into running interface e While Back press Enter to return to file editing interface If you want to give up operation press MENU to go back to the main menu 2 How to review and modify an Old Program File Enter the main menu and press MAIN MENU or AGA to move the 1 13 Filed New Sys cursor to File then press Enter Select File and press ENTER Press or ED to scroll File ZA and display existing files in item File 1 14 Run o FA F indicates six certain prepared files in system e 10 34 indicates files defined Edit by clients Firstly press q or q to File 19 select one existing file to edit e g 1 15 Run Edit File 19 then press qe or to move the cursor to Edit and then press Firstly select the file to Enter be edited then select Edit and press ENTER User 5 Manual Nucleic Acid Purification System BIOER Press BH or to shift between different segments and revise various parameters please refer to Seg 1 on How to edit a new program file
10. 0 60Hz Filter amp lnlet 3EGG1 1 Si Switch uaa EI poner supply u21 S924 MW PS 65 24 6 ACLO yg ACLI ACL pCv E Ls Aaa a 2 5 F SN PE Acn pcv IE S acn N H Rewer plug abe a acho acn 1 3 pe pe FUSE inside E F 250V3A 5 20mm AC DC power supply GND BY Q500212000000 U20 FEV MW S 25 5 vec 1 act q pcv PL Gu 2 5 27 ACN DCV Left limit switch sno sl E i might Limit switch y 217 SS0504 SS0504 a DB9_RS232C es o U21 zi Es VFD 3 o u20 BYQ900216000000 J13 1 2 DC5V 2212377 Og GNDJIO9 rmm 6 OUT6J10 10 8 N VCC J10 8 Key board 552 2 S lt GND J10 3 u22 20 30 2 OUT7J10 2 ge so VCC J10 1 CN1 5 VCC J10 7 CN2 zd GND J10 5 oa CPU Board ida Safty U19 nser EE SX671A Horizontal senser U23 A3144 BYQ500211000000 CPU Board u15 Motor driver M420 y Motor 42HS03 u10 GND J15 3 SEN4 J154 VCC J15 1 Motor 42HS03 BY Q500210000000 5 5 sog ooor So N s929E2803pE2s 3 gt 2 gt 00E gt 2 gt 3005 aoqot cqoqo8 ARR 6 6 5555553955352 5 m E N vcd SE Ss c pLuss S S P ois 7 5 E 5 5 At Br B 22 J5 1 VCC J5 2 PLUS3 3 VCC 4 DIR3 J5 5 GND J5 J5 VCC J9 7 GND J9 5 SENS J9 6 GND J9 9 OUT11 J9 10 VCC J9 8 GND J9 3 OUT10 J9 2 VCC J9 1 up limit swith Motor 42HS03 DOWN US A3144
11. Du ue a te e a e t ta te Dec ens 6 5 How to place 96 well deep plate sise 6 6 Poweron procedure ore E n OE Ur te Perte tt nn te 7 CHAPTER4 OPERATION GUIDE eerie e tn e e ee e eee te tee te toe te e e ee ren n e e s 8 1 Howto edit a new program file sie 8 2 Howto review and modify an Old Program File 11 30 HOw to delete a flle toe ae A i eie esee Ee Eee Paese deeds 12 4 How to run pause file ee ete ette ette rt e ete eee flat etes 13 5 Review system default file sise 14 6 Protection Interface icc cs etn rtr Aa 15 7 Interface of Operating Micro computer ss 15 CHAPTER 5 FAILURE ANALYSIS AND TROUBLESHOOTING seen 21 Annex1 Wiring Dla gra UR ERES 22 User s Manual Nucleic Acid Purification System BIOER CHAPTER 1 Introduction This chapter briefly introduces the feature of nucleic acid purification system and its applications 1 Features This type of instrument adopts a magnetic bead extraction technique to extract and purify nucleic acid through precision transmission of singlechip controlled step motor It has the characteristics as follows small volume light weight low noise full closed workaround vivid VFD display transparent working chamber for easy observing the work conditions touch panel with beautiful appearance and easy for operation It has powerful functions such as door open protection position out of limit protection and warning which ensure its safety and reliability
12. Nucleic Acid Purification System NPA 32 User s Manual Hangzhou Bioer Technology Co Ltd Note The Bioer Co reserves the right to modify this manual at any time without notice Patent materials are included in this manual All rights reserved No part of this manual shall be photocopied reproduced or translated into other languages without written permission from the Bioer Co Please read this manual carefully before operating the machine File No BYQ600200000000 ESM Version Nov 2007 1 6 Rev Important Note 1 CONVENTIONS Note Because of the important information in this column please read it carefully Failure to follow the advice in this column will possibly result in damage or malfunctioning of the machine 2 SAFETY During the operation maintenance or repair of the machine the following safety measures should be taken Otherwise the guard provided by the machine is likely to be damaged the rated safety level to be reduced and the rated operation conditions to be affected The Bioer Co shall not be in any way responsible for the consequences resulted from buyer s not observing the following requirements a Grounding Considerations A C power s grounding should be reliable for fear of an electric shock The 3 pin plug with the machine s power line is a safety device that should be matched with a grounded socket Never let the third ground pin floating If the 3 pin plug cannot be inserted it is recom
13. Seg 001 1 16 Loc 0 Move M Pres till Seg xxx 1 Move E 1 17 Loc 0 e f you want to add a new segment press till the end of the file and press V or to move to item Move then press EY Change E to others or to adjust its parameter as Seg xxx 1 Move M NOT to be E Set other parameters 1 18 Loc 5 Hold 20m20s well and press Ente to go on editing f you only need the several top segments of the file press or to scroll screen to the segment that need to be ended and adjust Move as E then press Entef to end the revision of the whole file and enter into file number setting interface Note Six certain files prepared by the system can be edited and can be saved as a file defined by clients e If you want to give up editing press MENU to go back the main menu at any time 3 How to delete a file MAIN MENU 1 19 File New Svs Enter the main menu and press or to move the cursor to File then press ENTER Select File and press ENTER File 19 Firstly press EY or ED toselect gt 1 20 Run Edit the file to be deleted then press or O to select Del and press ENTER Firstly select the file to be delete then select Del and press ENTER Delete File 19 When screen reminds whether you want to 1 21 Yesil No delete the selected file press
14. d be separated a distance from the machine Never cover or obstruct the openings of the machine which are designed for ventilation and to prevent the device s interior from being too hot When a single device is running the shortest distance between its openings and the nearest object is 25cm otherwise when two devices or above are running at the same time the shortest distance is 40 cm Do not place the device on a soft surface because that will result in adverse ventilation near the device s bottom openings Too high temperature will lead to degraded performance or failure of the machine Therefore the device should be protected against any kind of heat sources like sunlight ovens or central heating equipment If the machine is set aside for a long time it is recommended to disconnect the power line to mains and cover the device with a piece of soft cloth or plastic to prevent dust from entering Note Once one of the following events occurs you are suggested to disconnect the power line with mains and contact the distributor or ask a certificated maintenance worker for help Liquid into the device e The device sprinkled or drenched The device malfunctioning giving off abnormal sound or odor The device falling onto the floor or its shell damaged Significant changes in the device s performance 3 WARRANTY AND SERVICE INFORMATION a Warranty The nucleic acid purification system is warranted for a period of
15. deep plate a There are four locking blocks in the 96 well deep plate Two locking blocks in one side have one small bump each with limit while another two locking blocks in another side have corresponding small bumps without limit but there is a slotted User 5 Manual Nucleic Acid Purification System BIOER block in the middle b Please slope the 96 well deep plate slightly when place it and input its borders into the locking block with small limited bumps then press another side of the plate downwards so that the slotted block with flexibility will keep off Finally the flexible slotted block will compress the micro plate tightly after the plate is input C Note please make sure that the 96 well deep plate is placed in leveling condition before power on 6 Power on procedure Turn on the power of Nucleic Acid Purification system the LCD will display self test please waiting That means the device is under self testing which will last for about 10 seconds Please wait patiently If the self testing is past the main menu will be displayed and the device is ready for operations such as file edit review modify or delete User 5 Manual Nucleic Acid Purification System BIOER CHAPTER 4 OPERATION GUIDE In this chapter we explain in details how to edit review modify or delete a file as well as how to run or stop the file Meanwhile we will introduce the meaning of the protection interface which appears during the file
16. dit duplicate stick insert or delete the actions you choose through choosing action line by pulling mouse if necessary s e Ris Ribose Untitled dt File E File E Edit E View V Help H E D a B3 8 2 X 60 P O First Hole Second Hole Third Hole Fourth Hole fifth Hole Sixth Hole Tip Position 1 2 3 4 5 6 Tip running 7 9 Please click Save after programming is finished e Riz Ribose Untitled E mis File File E Edit E View V Help H El o Undo uy Gritz 25X Go P Cut T Ctri x Copy C Paste P Ctrl PV Insert Up Insert Down Delete Seleted row Run Sixth Hole Tip Position 1 2 3 4 5 6 Magnetic stick running Tip running User 5 Manual Nucleic Acid Purification System BIOER 7 10 Run the procedure after choosing the edited file JL Ri Ribose Untitled File E Fle E Edt E View Help Tm New N Ctrl Open O Ctri o g 2 X 6e P Y Save As A Print P Ctrl P Print Preview w Print Setup R LEAUE SH 112 22m EigiteHmoio Exitx Tip Position Tip running 20 Nucleic Acid Purification System B E R CHAPTER 5 FAILURE ANALYSIS AND TROUBLESHOOTING In this chapter we briefly represent possible failures reason analysis and troubleshooting Failure analysis and troubleshooting
17. ing e Turn to the upper segment when pressed in the menu of file editing cursor moving PgDn e Select different item when pressed in the menu of system setting Turn to the next segment when pressed in the menu of file editing Function key confirmation in file setting press to accept the current setting value or selected item and display contents of next page User s Manual Nucleic Acid Purification System BIOER Note In system setting menu press to save the current setting value and stay in the current menu Function key press to select set file number or setting parameters by rolling Function key press to select set file number or setting parameters by rolling Start Pause when file is running press to stop running file and press one more time to restart file running Pause press to stop running file when file is running and the system will turn back to the main menu Insert press to insert one segment during file edit Delete press to delete one segment during file edit Press to turn back to the main menu 4 Check up before Power on Before switch the power on please check and ensure that 1 Supply voltage falls within the specified limits refer to Chapter 2 2 The plug has been inserted into the power socket reliably 3 The grounding of the power line is reliable 4 Make sure that the 96 wells micro plate is put in the right place 5 How to place 96 well
18. ion of maximum moving distance parameters Note When setting value in MOVE is P and LOC displays press qi to 5 unchangeable moving distance is default enter Hold Press or AD to move among time period Hold Set dwelling time after moving part stops Seg 001 Move M It should be between 00m01s to 59m59s 1 4 Loc 5 When cursor is at tens place press Eh or E toincrease decrease ten Press Enter minutes or ten seconds E omer Press to When cursor is at units order press Seg 002 after Ws bide sd or ED toincrease decrease one setting Seg 001 s minute or one second parameters As per method of setting Seg 002 Move T parameters in Seg 001 to go on 1 5 Loc 2 with setting Seg 002 Press Enter to enter next segment Press to go after setting Seg 002 parameters back and reset Seg 003 Move P 1 6 Loc 5 Set XX segment parameters Seg xxx Note 1 7 Loc 5 Normally if a micro plate P moves five times in one file it can complete a purification experiment So if setting value of P exceeding five times it will automatically stop after five times moving Press Enter to Press D to go enter ending segment back and reset after setting all parameters User s Manual Nucleic Acid Purification System BIOER Set MOVE as E will enter into ending segment and press ENTER to end Seg xxx 1 Move E edition of the file and enter file number 1 8 Loc 0 Hold 00
19. m01s setting menu e f you want to revise previous segments during editing process you may press to go back the segment you want to revise After the revision press ENTER then press or to shift among different segments and go on editing e f you want to delete a segment just press DEL to delete it after you enter this segment f you want to insert a segment before one e g Seg 003 move to this segment Seg 003 in editing interface then press INS to insert one segment for edit After editing and confirming the new segment the segment s insertion is accomplished but former Seg 003 will become Seg 004 f you want to give up editing press MENU to go back to the main menu at any time File number editing interface Press or EY tosetfile number File 10 whose range is from 10 to 34 Press or 1 9 Runi Save to move the cursor to Save then press Entef to enter file saving interface If the file exists already 1 10 File is being 1 11 saved File 10 exist 1 12 Renamell Select Rename and Press ENTER Here it shows the file is being saved after about five minutes later it will go back to file number setting interface User s Manual Nucleic Acid Purification System BIOER If the file already exists press or G9 to make the selection e Select Rename and press Enter to go back
20. mended to ask an electrician to install an appropriate power socket b Keep Away from Electric Circuits The operator is not allowed to open the machine Changing components or adjusting certain parameters inside the device must only be accomplished by the certificated professional maintenance personnel Do not change elements while the power is still on C A C Power Considerations Before turn on the power always check and insure that the mains voltage is within the required A C 100 240V and insure that the current rating load of the power socket meet the required specification d A C Power Line Considerations As an accessory of the machine the A C power line should be a default one If it is damaged the A C power line can not be repaired but must be replaced with a new one The power line should be free of heavy objects during the machine s operation Keep the power line away from the place where people ambulate frequently e Connect the A C Power Line While connect or disconnect the power line you should hold the 3 pin plug with your hand Insert the plug thoroughly into the socket to ensure good contact between the plug and socket Pull the plug not the line when you need to disconnect to the mains f Design Environments The machine should be placed in a low humidity dust free and good ventilation room without caustic gas or powerful magnetic interference In addition water sources such as pools and water pipes shoul
21. ods shall conform to such description Note Once it is opened the package should be checked according to the packing list If the buyer finds any items to be missing or damaged do not hesitate to contact the distributor Please store the package and packing materials in a safe place in case of future device maintenance The above warranty does not extend to goods damaged as a result of cheesy package Aftersales services hotline 86 571 87774558 User s Manual Nucleic Acid Purification System BIOER CONTENTS Important Note core tire tie ere ee tai 1 T CONVENTIONS gt dax acte Lec LA LA Lp LEUR OE eU Go SUN cO eA M ec 1 25 uSABETY o eR LLL LL ee tee 1 3 WARRANTY AND SERVICE INFORMATION nennen nnne nennen nennen 2 GHAPTER 1 Introd ctiorn aa 1 A O 1 2 APDIICATIONS D ieee icv eis vie ei vl vl ere E 1 CHAPTER 2 SPECIFICATIONS a e a e E ae 2 4 Normal Working Conditions dado da at 2 2 Transportation and Storage Conditions 2 3 Basic Paramelters epe tente rper e a e en ee net ape e ape A REO S ee 2 4 Performariees iitoieiecutecedeceec ttc A ee ERU Qe CER ue eund ADA 3 5 Software FUNCOMS or tre P Pn be nee 3 CHAPTER 3 A PREPARATIONS pereto an otin reste None None aee e ee e en i niin 4 1 Str cture DDescriptiQmnys t cote cos 4 2 Touch Panel BIagramz oer uiuere eeu 5 3 Jntroduction of pressing Keys ooo rre ie ie e e ee nu ee rers 5 4 Check up before POWer Ofn re et e beth eee e Ce ce Duce
22. of running when unexpected situation results in moving part exceeds maximum position an exceeding Location Out position limit protection interface will appear meanwhile the buzzer alarms and the file stops running and then go back to the main menu 7 Interface of Operating Micro computer You can program set and run files through connecting the machine with computer by RS232 connection please refer to the following steps 7 1 Newly built files Newly built files in the pop up menu from File Column F S Ribose Untitled B 18 xl File F Edit E View v Help H ME EB 8s e amp 2 X eo P Second Hole Third Hole Fourth Hole Fifth Hole Sixth Hole Position 1 Action Position Time Second User s Manual Nucleic Acid Purification System BIOER 7 2 Choose operation holes Each hole location means one line 8 holes EA Ribose Untitled 18 x File E Edit E View V Help H Dc XB5 amp 8 amp 5 9 2 x 6 P O Second Hole Third Hole Fourth Hole Fifth Hole Sixth Hole Position 1 2 3 4 5 6 7 3 Click the pop up menu from Action Column then choose Bar Magnet Action or Tip Action Ribose Untitled j la xl File E Edit E View V Help H 0 S eal 2 X Go P com 1 zl Qv Second Hole Third Hole Fourth Hole fifth Hole Sixth Hole
23. one month from date of shipment from the company to be free from defects in material and workmanship The Bioer Co shall be obligated under this warranty to exchange the nucleic acid purification system which proves to be defective as described herein The nucleic acid purification system is also warranted for a period of twelve 2 months from date of shipment from the company to be free from defects in material and workmanship The Bioer Co s obligation under this warranty shall be limited to repair or exchange at the Bioer Co s option of the nucleic acid purification system which proves to be defective as described herein The buyer is responsible for sending the machine to the maintenance shop designated by the Bioer Co on all warranty claims The buyer is also responsible for the transportation expenses of the freight to the maintenance shop and the transportation expenses of the freight from the maintenance shop after it is reapired After the warranty comes due the Bioer Co reserves the right to charge for maintenance of a defective device b Warranty Terms The above warranty is not applicable to defective devices with incorrect use abnormal operating conditions improper application and unauthorized maintenance or alteration The Bioer Co makes no express warranties other than those which are described herein Any descriptions in sales promotion under specific conditions shall not create an express warranty that the go
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