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GHS分類、マニュアル等調査（PDF形式：9231KB）

Contents

1.
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19. e 1 5 f 1 6 2 8 8 1 b 1 101 3kPa
20. n 3 pH2 pH 11 5 1 pH 2 11 5 pH 1 qu o BORSE LORE TRUE 7 DX 160 E 1 0 1
21. p HS N I TE GHS 500J g 500 300J g 50kg SADT 75
22. 1 c GHS 4 2 15 2 1 GHS 4 1 2 Gas G 50 300kPa Gi 101 8kPa 20 Liquid 50C 300kPa 3bar 20 C 101 3kPa 101 3kPa 20 Ef Solid
23. JIS SDS GHS GHS GHS T xh P 1 2 GHS r Ay GHS 40 BEC
24. gt P201 P264 P264 P233 F mm O OO gt RAO
25. NITE GHS b WELT D H HH Fd HH SDS H I iH 1 SDS
26. 1 f 4000 2 1 2 1 2 1 2 1 GHS gt SDS
27. ASP 2 3 5 9 ASP ID YE H Web DB
28. 1A 1B 2
29. ASP ASP API
30. 3 E 1 1 2 0 1 T CR 2 2 2 ATE 1f H I m g
31. Fil PC VT 1 1 2 3 5 2 Web Web CD ROM
32. d 300J g e 50kg SADT 75C 5 a c B POF H A PDG 7 a i A
33. 2 85 60 L 2 3 4 2 3 3 d 2 3 7 1
34. 74 F FRA eer SPURS 1 2 PC PC 4
35. 1 2 3 4 5 6 7 8 9 1 H225 H315 H317 H319 H351 SAS CIO Ce AER CREBRA TI CU S 15S BES SIBI EDO H360 H370 H372 H401 H411 Q GO NS
36. F Q 54 Fr gt BHS MSDS gt 2430 ret 1 561 580 MA 25 26 27 28 29 30 31 32 33 34 X Q MARIS HRB 29 122 4 EF Ib f 997 VV 3 Octan 3 one 4 Vin yloyclohexenedioxide 4 4 Vinyleyclohexene dioxide 106 87 6 1 2 1 2 Butylene oxide 1 2 1 2 Butylene oxide 106 88 7 Epichloroh ydrin Epichloroh ydrin 106 89 8 PLEJ JY Yk Glycidylacrylate x55 g2 3 XIIIE 3 o 2 3 Epoxypropylme th acrylate 06 91 2 CX EYE T W
37. P405 gt P405 2 Fa mx mur er C gt B 2 1 2 4 MIXTURE product_number Test 1 product_identifier synonyms un_number 1263 statements LABEL product_identifier symbol PICXflamme jpg symbol PIC exclam jpg symbol PIC silhouet jpg symbol PIC pollut jpg signal wds fifi hazard statements H225 hazard_statements H315 hazard_statements H317 hazard_statements H319 ha
38. 1 ECS Al H H 1 iH SDS GHS 1 H GHS RY ADIL M SDS o 1H 1 1 iH HEED GHS EU 67 548 EEC
39. 2 a rera UR 5 96 16 ond D NECS om b A tOBOENERE Gr 2 x dE 8 1 8 D a 1 Ma 1 Wr 21
40. x i i gt N CD m F m gt c x Co gt c ct x n gt ien ct x g0 3 Acute Tox 3 H301 Toxic if H301 Toxic if H301 Toxic if H301 Toxic if 6 1C Acutely swallowed swallowed swallowed swallowed toxic oral H312 Harmful in H312 Harmful in H312 Harmful in H312 Harmful in 6 1D Acutely 25 Fi 3 3 UI contact with skin Acute TR contact with skin AGE Tous contact with skin Acute Ox contact with skin 4 toxic dermal HF d Ht h H332 Harmful if H332 Harmful if H332 Harmful if 6 1D Acutely Acute Tox 4 inhaled inhaled inhaled toxic inhalation 6 3A Irritating to the skin I WE Acute Tox 4 1332 Harmtul it inhaled 3 Sina 91S Causes deo SIO Gases Sa 9 Bevo Causes leinig skin irritation skin irritation skin irritation skin irritation H319 Causes GAL VAR TRU 2A Eye Irrit 2 serious eye to the eye irritation T H317 May cause
41. e g G 50kg 5 V amp TUI ANTE CHE b IREEN LZR DS lt ER ITYPEA TYPE GI B C 4 60C
42. API Applieation Program Interface NN 14 2 3 4 2 3 4 EU 2 8 5
43. GHS 3 2 3 3 6 z 5 1 1 GHS 3 8 8 8 1 1 3
44. GHS 1 3 3 2 GHS 3 3 3 3 6 5 6 5 6 1 4 GHS 4 1 2 1 1 RD 2 4 1 1 4 GHS 4 1 2 1
45. O GHS GHS GHS 2 1 2 GHS ERS GHS
46. 3 1 GHS GHS E Tu ae cc E GHS
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50. Y Y A Y n ng b summation method G 1xM 25 1 Mx10x 1 gt 2 295 Mx100xy 1 10xy 2 gt 3 295 Gi 1xM gt 25 1 Mx10x 1 2 gt 95 Mx100xy 1 10xy 2 3 225 Gii M moe NEN 0 0001 L E C50 0 001 100 10 YE NED ND 28 412
51. 2 G G 2 1 G 2 b
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55. J TBS Mesapmame Simek CSA BESEM MELD ORL 125me ke D RES g CERL NTER ver 1N 8 FSGS BH M COME i 2 SEU TO F325 s00me ke CE BTE RS RB CERT NITE ver1 1No 74C00t li D s Magan RAB LOE OMERLDAERE OREN 2311 1853 3 SHE CEDE ico CERRO CLR 5 VAM325 500 me ke MA LISA See C IASI CATR AS Ehe NITET ver 1 1Na 742008 gt s t ORE DID PIER HUC 2 EHC33984 1 13 50ppm 0189mg L CERT NITE yer 1 1No 74 08 A IZER L JS0ppm 0 189 me L CFR PE AR ABE CERI NTER ver 1 1 No 74 2008 XEIR Up QT ne L CRRRREDCH SEIS EPOD sr RS IFES sa CEPS Ch a ONE rus ML Ru EI a EEE 2534 RES ares 1 MAZ EEF ver 1 1No 100ppm TERIS ERO 35 arame GOGH SO 29me D CIBO SRE BIL ECHOS ACGIH QUU Dec RGB EO 0 095me D L ECHR BIBRA WAT DAS
56. 1 a b lt 45 gt 2 2mm 5 2 4 b lt 45 gt 2 2mm gt 5 10 2 3 8 1 A oboe mO a 2 3 1 GHS b 2 3 13 2 3 14 5 2 3 15 GHS
57. 2 1 2 4 2 2 2 GHS GHS 2 2 1
58. GHS GHS GHS GHS DR ene
59. GHS DLL DLL Dynamic Link Library Windows DLL GHS JIS DLL URL DLL Windows Update TI VT ae sZ 2 NS 8 2 3 2
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61. GHS 8 1 8 3 ou 4 1 C 1 GHS 8 2 8 8 1 1 3
62. conclusive but 3 data lacking not sufficient for data lacking classification EE but Sono data not sufficient wl data lacking ATU conclusive but data lacking not sufficient for data lacking classification 2 4 2 2 CLP 79 06 1 p23 5 6 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 mE Sud j j lud x cgi Acute Tox 2 Acute Tox 3 Acute Tox 3 Acute Tox 3 Acute Tox 4 AueToxS Jelo Aerox4 e o jololololololololololololololololololo Benmt2 wis o o o o e 1 Bem2 wa o fof olololel lelelelelelelelelelelelelelelel Sknsens 1B nm TE e Sknsens 1 o olololololololololololololololololololololol Ho o mlolololololololololololololololololololololol cae i o o o o o Repr2 wer o BToTRE1 72 o o o o
63. ITE http www safe nite gojp ghs ghs_index html http anzeninfo mhlw gojp anzen_pg GHS_MS http www jetoc orjp safe ghs html http ncis nier go kr ghs D_FND aspx HS GHS MSDS GHS GHS ZVAT 203 2435778 2011 10 m 15 000 NITE 27 Wi W y E r O z NS Md x HS CAS 2 450 mm 2011 3 30 x x a 2012 3 16 Web SDS JETOC GHS x II C x GHS 2006 02 10 MSDS
64. Screening Information Data Set SIDS Initial Assessment Report SIDS Chemicals 23 4 41 BAR GHS Ez DIC KE MES IT
65. ss J o T k 6 8E WED MER YS gt GHS E amp xExJA gt GHS 24 gt FSB ADEN c THs Siu lO Tet FI ME TE 58 FSS 3 x 2 1 10017 323 w epichlorohydrin e AEOH 101 Se f 5 68259 2m CAS a AIS tH X E z see 5 ga veo SAA MIS ee gispst nx 3 H226 ad 53 37 3 H301 ed 53 30 3 H311 GHS06 000106 2A 3 GHS05 8 H331 1 Epichlorohyd 97 1 192 85 8 GHS08 WS AA GHS02 pps 1 H314 lt yF 1 H317 ge 1 H350 E FAIA T 2 H315 lt Reaction Ge RANA products of 24 2 H313 epichlorohydrin 2 2 2004 1 544 5938847 aye GHSOT 2 Ha7 68 9 GHS09 mercaptoethanol 34 sodium sulfide SAHAR Liane 1008 GHS 1 ils Epichlorohydrn SJE X SS HSS GHS AAS Page 1 of 3 auzx hn lal j 22014 POMS Korean gt English Jepanese Chinese RREH AN RS s PI Epichiorohydairg omge2z5i cel Epchiorohydan FE Supplier information OSTIA TE VU VIE BS 18 AH Pictogram SH Signal Word 32124 Fe HBSS Hazard Statement H311
66. GHS 18 2 GHS 2 4 2 e EU ESIS European chemical substances information system RC No1272 2008 CLP VI 4 136 GHS a ECHA European chemicals agency A On E RC No1907
67. 2 1 2 15 Hi DAN 2 8 1 2 3 7 1 2
68. Excel Word 2 PDF PS Post Script 4 D a Windows Visual Studio Excel Word CSV Excel VBA Excel Word SDS Excel Word
69. GHS JIS E GHS GHS 13 GHS I1 E HX PS GHS GHS TT
70. 2 8 1 2 GHS JIS 2 3 1 Windows Windows NET HTTP 2 8 2 2 3 2 GHS
71. 2 8 5 1 2 3 5 2 WEB ASP edes Oracle Express Edition MS SQL server Express DIED PostgreSQL MySQL 2 3 6 2 8 6 ASP 2 83 5 PC
72. LD LO so k ppm mg l D m
73. 2 3 1 Not applicable GHS Not classified a gt gu S id 2 2 1 GHS 2200 E
74. P201 P264 P264 P233 P 2 ENTE 5 OO gt P307 P31 1 CEOs 2 18 SAD
75. 3 1 1 1 1 2 2 GHS 8 1 8 6 1 3 1 3 6 2 3 ATR 3
76. GHS UNRTDG GHS 2 2 3 9 3 2 3 2 2 8 4 ISO 10156 2010 1 2 4 80C GHS GHS 5 GHS
77. GHS 2 2 2 JIS GHS Bg 2 2 fi 2 2 2 2 8 3 GHS 4 10 ALA
78. s 2 4 1 1 GHS UN SCEGHS 20 INF 5 Committee of Experts on the Transport of Dangerous Goods and on the Globally Harmonized System of Classification and Labelling of Chemicals Sub Committee of Experts on the Globally Harmonized System of Classification and Labelling of Chemicals 13 October 2010 Twentieth session Geneva 7 9 December 2010 Item 4 a of the provisional agenda Implementation of the GHS Implementation issues Updated consolidated comments on the survey for existing international classification lists of chemicals Transmitted by the expert from Australia Introduction This document contains consolidated comments from GHS Sub Committee experts regarding the survey of international classification lists of hazardous chemicals updated with additional responses received from member countries and observer experts of both the UNSCEGHS and UNSCETDG The survey was circulated on 3 February 2010 and again on 23 July 2010 with responses requested back by Friday 26 August 2010 All the responses received are listed in the annex to this document The questions in the list of consolidated comments are as per in the original survey and the responses from each country international organ
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80. Ta ISO 10156 2010 Table 2 i i b n Ki 15 ISO 10156 2010 Table 1 2 3 3 1 EE GHS GHS 2 3 6 2 3 2 2 3 7 75cm 1 a KAORE 20cm 2 XIX 4cm 7 a 75cm 20 kJ g
81. 2 2 E 1 0 3 1 6 D 1 1 1A
82. OS Microsoft Windows IDE uil NET VB Java PHP IDE Microsoft Visual Studio Eclipse Eclipse NET Framework Java VM Apache IIS PHP 1 2 Windows Ez T4 TY Web Web Web 1 2 NRT windows NET ASP
83. 2 2 3 GHS 83 1 8 8 ATE 1 4 LD LC ATE GHS 5 11 5 LD LC s0 ATE ATE 5 1 5
84. Maximization gt CERI NITE ver 1 1 No 742008 invivo gt CERI NITE ver 1 1No 742008 PATI 5th 2001 DS I RD DC 2e OUR lt BCLS ER O RE R 3565080 CEDAR invivoR 5 MINER 2 T y AREEN CERI NITES LESH 1 1 74 ID 0D S5 D SRE EESTI GH m 1 TARC 999 C2A EA NTP2005 1B 2 1 0mgykgydayy QRISGnn8 3 OED EERE AL QRISG008 c 2
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86. a x b wa c d e f g b i UNRTDG GHS ISO 10156 2010 2
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90. K lt 2 a E 6 A6 1 b CWS ORAZ 200 CxHyOz x y 4 z 2 O2 x CO2 y 2 H20 1600 2 x y 2 g c 500J g 500
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92. 11 2 3 12 1 1 1kg 10 m 1 1kg 20 1 1 3 1kg 1 1 2 2 3 13 1
93. PDF SDS pdf 2 3 8 2 CSV PSV XML Excel PDF Z f un S O 7 APE RAE Adobe Excel Reader
94. GHS V 1 lt gt espe 22 18 11 15 19 23 gt Y GHS x 13 17 21 25 N 12 16 2024 N Y 2 1 2 3 a Ex dud
95. Xx 1 0 1 29 2 2 3 1 1 1 1 2 bridging principle
96. 2008 3 31 FAB R 1 200 2 d 000 OOOO AA A A A 03 1234 5678 03 1234 5678 03 1234 5678 STP O EME DHEIN Z HEN 3 BRENER NET KETTLES BALTES BRI SDS 2 3 3 AWEH EF S CHE 1 1 1 1 2 1 2 EA 2 3 88 gt
97. EU CLP VI K 3 1 GHS EU EU REACH CLP GHS GHS 2 TUCLID5 nternational1 Uniform Chemical Information Database GHS GHS 408 E Hj GHS 20 3
98. 5 6 2 1 1 0 1 ww 1 ww 0 1 E GHS 4 1 3 ri 5 6 3 GHS 4 1 3 3 2
99. 1 a 1 10 20 5 mm2s 40 b 1 10 40 20 5 mm2 s 25 4 4 1 411 D a VRF 1 96 LCso 48 ECso 72 96 ErCso lt 1 mg t MIE lt 1 mg l X lt 1 mg t 2 96 LCso gt 1mg X10 mg t 48 ECso gt 1 0 0 X10 mg t 72 96 ErCso gt 1 108 0
100. Boy CHIL ORES BR ATA 8 1 Bat cats DUNS x EGESOSE BORE ZL ERR AERE AAA TORS 11 Environmental Protection Authority Te Mana Rauhi Taiao Contactus A Zindex Publications News Consultations Secure login Site Search Q Home About Us New Organisms Hazardous Substances Resource Management Emissions Trading Search our Databases You are here Home gt Search our Databases gt HSNO Chemical Classification and Information Database IN THIS SECTION p g w bf HSNO Application Register Controls for approved hazardous substances HSNO Chemical Classification and Information Database New Zealand Inventory of Chemicals NZloC HSNO Equipment Registers HSNO Test Certifiers Substance Exposure Limit Register HSNO Chemical Classification and Information Database CCID The CCID is a database of chemicals we have classified in accordanc
101. EOCHA NITE cix HER 33 CLP GHS ECHA GHS CLP GHS 23 12 LI REACH M GHS CLP GHS EU GHS GHS
102. GHS JIS GHS 4 2011 JIS JIS Z 7252 2009 GHS 2 JIS Z 7253 2012 2010 3 2 9 29 E 3 GHS
103. 12 2 3 15 1 a 1 0 1 0 b 1 0 0 5 O E 16x Y 1 Y 1 mi i Bed 7 n X C J m i lt A b c d 3 i
104. 1 a WE 1 1A 1B b BOUES EM E
105. 140 100mm 140C 25mm 140C 3m3 b 100mm 140C 25mm 140 100mm 120C 450 c 100mm 140 25mm 140 100mm 100C
106. 3 30 1 1 0 1 0 2 1 0 7 0 0 5 1 1 3 1 1 3 2 1 2
107. Several lists are maintained by EPA USA Question 5 Is it publicly available Response Country Organiz Not applicable Argentina Yes both the HSIS http hsis ascc gov au Default aspx and the SUSDP Australia http www tga gov au ndpsc susdp htm susdp are publicly available Yes the CLP Regulation is publicly available via the Official Journal of the European EU Union http eur lex europa eu LexUriServ LexUriServ do uri OJ L 2008 353 0001 1355 en PDF The Inventory will be publicly available via the ECHA website Not applicable Canada Yes from the IMO website published as the GESAMP composite list document IMO BLG 1 Circ 29 Annex 6 latest version 30 April 2009 Any type of the list of chemicals is publicly available Japan Yes the information is publicly available via KOSHA homepage members only Korea e http www kosha or kr Yes at http www ermanz govt nz hs compliance chemicals html New Zealand Access is also available through the OECD eChemPortal at http webnet3 oecd org echemportal Norway will implement the EU regulation on classification and labeling of substances Norway and mixtures CLP See response from the EU commission Not relevant because of the reasons given previous responses question No 2 and 1 Serbia see remark regarding questions 2 16 in the answer to question 1 Switzerland Yes SE EAQB UN SCEGHS 20 INF 5 Response Yes The list
108. a a a ead GHS b GHS NITE o cc GHS GHS IT 3 1 3 2 GHS
109. 2 1 2 2 3 3 2 8 3 1 2 3 8 2 Word Excel PDF Excel TSV
110. 3 233 precautionary_statements precautionary_statements precautionary_statements 11 precautionary_statements precautionary_statements precautionary_statements precautionary_statements 1 precautionary_statements precautionary_statements x CB SRI L 2 lias OD E 1 act cf 2 C O jiwa RUP HORE D gt DARED AE CRS 6 BREN Ia E ODER 5 DARED AE CILE F
111. JIS SDS JTS JIS JIS Z 7251 2006 JIS Z 7251 2010 ali SDS JIS JIS Z 7250 2005 JIS Z 7250 2010 JIS JIS Z 7252 2009 JTS Z 7251 2006 JIS Z 7250 2005 SDS JIS Z 7252 2009 GHS GHS GHS 2 JIS 2 GHS GHS NITE GHS 2200
112. 2 data lacking of damaging not sufficient for reproductive or xd classification developmental 1 1 conclusive but conclusive but ing GE data lacking not sufficient for not sufficient for classification classification 6 9B Harmful to conclusive but conclusive but human target I 1 1 E E ss data lacking not sufficient for not sufficient for organs or UN PET classification classification inhalation 10 conclusive but conclusive but data lacking not sufficient for not sufficient for classification classification EU REACH _ O Te Official classification o omma suem 9 1D Slightly harmful in the conclusive but conclusive but aquatic 3 E33 data lacking not suffici
113. H 0H H GDS SDS 1 27 HH FE fj 4 Ae Tee C3 5 LH GHS Web ASP d
114. GHS b GHS o SDS d ali J ali 2 1 1 2 9 4 4 1 Web 2 2 1 1 3 ali alli al a
115. TT Me GHS PRA IT GHS MAE 2 21 2 1 1 1 SDS 2012 1 16 2 1 1 1 a JIS GHS
116. gt 2 1 2 2 2 8 1 2
117. 1 E ORA 2 GHS 3 E v 3 IT 4 GHS GHS GHS HHL gU NEG DAO S lL loo
118. Ada B I 5354 Rey ORR LLL 51 75 2 2HH GHS 02 7E 97 19 21 H222190GK H18331 ID21B3085 GAS 106 89 8 G m o peame E lt Jo 2 GHS ee 4 ARR 3 GHS E m i GHS 3 BC CSO2003 23C 60C 3 1 ie GHS PEI DD SIRESUD T Sta COSI aL 6 385 CSC 2003 IUCLID C000 411 C NFPAM 3th 2002 70C E essem oo ERR NON
119. CD ROM OS DB A FE A PC CPU HDD 64bit 32bit Zee 286 DB CD ROM A x 2 8 6
120. CERT NITE ver 1 1No 742008 ACGIH 001 gt HT VAM BS TUI ME SSB E SRO MMAR NITE yer 1 1No 74 008 HIT CERI NITE ver 1 1No 74 008 2 1 READS STS IaRG71 1999 697ppm 6 4 3957mg L 0 DRE BERENS CER SE ver 1 1 No 74 C008 ALUSY F CI 3283 445ppm GRO f 1 608 1 684me L TARO B HM CIRIS Q008 DPA AROS 1 gt
121. vvesRtosn s Pe MORE The amended ist of GHS classification and labelling OIC GHS HAH 47 SSS UN GHS AXE HS EH for Toxic Chemicals Hense GHS SSS Heo HE ola sal HE GHS UHAHH 8 m x HEA gt The amended list of GHS H GHS WHAHA 393 p J GHS 23218 Helo HE oa S HE GHS 219 0 SS Coa ori Aw gs NCIS 2222224 404 708 ANJAN AF BMS SSAA HEUS 032 560 7114 gla X 032 560 7223 6 COPYRIGHT C National Institute OF Environmental Research ALL RIGHTS RESERVED SsUEA 209 153248 100 GHS TSS GVEA SS 555 GHS A lI A windows Internet Explorer Go e http ncis nier eokr ehs search toxic contain chem label jsp CurrentPage 1 amp listCountzl amp search type ACHEM YOODOK NAME ENG amp search wordzepichlorohydrin amp v amp gt Google gt gt FE RRO RTV YMD AIH Google v gh gt 4 Qe amp GIO Google Google
122. route organ category 1 SINGLE EXPOSURE nw route organ IE Je gs category 1 REPEATED EXPOSURE route organ category 1 REPEATED EXPOSURE 1 route organ category 1 REPEATED EXPOSURE 1 route H P501 organ category 1 REPEATED EXPOSURE route organ list category 1 2 2 2 1 1 1 GHS 2 Classification not possible GHS oo
123. 3 2 24 48 72 3 HE gt 1 5 b 2A 8 2 24 48 72 1 BR 21 2 22 21 7 1 2B
124. 50C 50C 50 2 a 50C 65C b 65C 2 8 6 Q 1 lt 23 385 C 2 lt 23 gt 35C 3 23 60 C 4 gt 60 93 1 55C 75C
125. D A 1 10 B 1A 10 12 s CROT ZO RACER RE ZAR x 1 2 t 1 1 0 1 1
126. 2 3 GHS 24 3 JCDE l B HENK ero E E E ot E UNE iu tcc uh oct eee E E I T 3 rokssecidnpc eem DNE T i c ARN ii remi ARTT TT al psp TELS URL ostio attt aed Sonet 4 PAP ME 22 GHS RER OJR oS Heb Ee eb Re bu e Pee oe E oe 10 2 2 l RELOJ TR SC Gas cie a b ix Ee peii ee 10 DOD TET NT AORERE OP rd P UD RN 10 2 2 3 JE ay ada C BUE NARKI IR os cea tena a dead 10 2 2 4 ee 10 T 14 2 8 1 iii 14 iui 14 2 3 3 2 3 4 2 3 5 2 3 6 2 3 7 v AS an DITO SUP c NNNM 14 lk 15 15 A a DY i i 15 AE O fee aed a Qa uama kk 16 2 4
127. 3 t L a GHS 1 3 2 3 1 12 M CO R CMR GHS 1 8 2 3 2
128. 4 3 1 RESER GHS OR LC50 634 2ppmCEHC33 1984 251 1ppm 1 GOO2 50ppm PATTY5th2001 3 2 1 KRS 2 Bs 2 1 3 2 1343 FERRE ATTIRE 21578 9ppm V 05908 EU ET 727995 ppmV SESE 1 24 ance Cat dI CE 82 248 A EARI CAL Y C ERT NITE ver1 1No 2 AL N nA ma Ere BEDRE USA CERI NITE ver1 1No 74 2004 ACGIHGth2001INIE EU C R34 1 ARSE EPO RLS SAFES OPE SPSS 10M Tl 3 1 CERI NITE
129. GHS GHS NITE 1 CLP XXX GHS lt gt YES UNTRG YES YES YES YES gt YES 5
130. 1A 1B gt 1B 2 2 1 x ue cxi prece
131. IASP PC InternetExplorer8 9 Firefox Safari InternetExplorer8 9 Firefox Safari DAR A Express SQL Server Express O Microsoft SQL Server Compact Microsoft Access SQL Server DB Oracle SQL Server Microsoft Access Web DB OS DB Microsoft Visual Studio Tools for x Microsoft Office System OS DB
132. GHS 18 2 41 GHS iui 18 2 4 2 GHS 19 d E UE ua anan a a aa set her 21 PME wale 21 22 3 3 EE eevee Seat or eget 22 1 1 SDS ML 1
133. v GHS w GHS cR u 13 2 8 IT
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135. ict GHS JIS 2 3 7 1 GHS GHS GHS _ rmx ae ee E wo zz 1 6 MER METTE bomo DOQOCOCI Hage USE EE KARE GHS IN X XXXX XX X GHS Y YYYY YY Y GHS
136. BME Cb 5 BURENS MET 5 CURITAF ELEY SEE O DL FAT ELIBAGSE COP ERIR tii lL Ca 500 Xem fr uz PURIR AFERAT PERE RIL CAE 2 amp 1 2 3 mg kg C 300 300 C 2000 REZ mg kg C 1000 1000 C 2000 ppmV 4 C 2500 2500 lt C 20000 mg L 4 C 10 10 C 20 Ee lt lt mg L 4 C 1 0 1 0 CS 5 0 a 1 2 EMEN M Tem 1 0 10 2 210 b 3
137. b B C d D G Gi Gi
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141. 3 22 NITE JETOC ESIS ECHA WTO IUCLID API SIDS SIAR GHS Safety Data Sheet EET eR Globally Harmonized System of Classification and Labelling of National Institute of Technology and Evaluation Japan Chemical Industry Ecology Toxicology amp Information Center European chemical Substances Information System European Chemicals Agency World Trade Organization TERUEL BE BS International Uniform Chemical Information Database Application Programming Interface
142. lt P302 P352 in P305 P351 P338 precautionary_statements precautionary_statements precautionary_statements S Dm 0 P405 P332 P313 P333 P313 i N P337 P313 precautionary_statements SUPPLIER supplier_identification address 3 9 2F phone 03 3239 5901 SINGLE_EXPOSURE 1111
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155. DB DB Web x HSNO GHS CLP DSD DPD CLP DSD DPD CLP DSD DPD Ai T L M m U 2 25 4 Ca ERAS tla 2 4 1 3 GHS 1 NITE GHS 2 GHS 3 EPA HSNO CCID 4 EU ECHA CLP GHS 5 EU ECHA CLP 6 EU ECHA REACH 7 GHS 8 lt gt 1 http
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162. RETO COM HJ AA E HEU SIE E P264 P264 EXE 2 D H precautionary_statements lt gt P210 precautionary_statements P260 precautionary_statements P260 precautionary_statements P261 precautionary_statements P243 precautionary_statements lt gt
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164. The HSIS does not use the GHS as a basis for classification at this time but will contain GHS classified chemicals from 2012 Plans for reclassifying the SUSDP for which the scope is domestic chemicals including cosmetics according to GHS are being developed Australia CLP list The list includes classifications of industrial substances active ingredients of Plant Protection Products and Biocides Inventory Under the CLP Regulation a notification has to be submitted for the following substances Substances subject to registration under REACH and placed on the market This will also apply to certain substances contained in articles where REACH Article 7 provides for their registration In case a substance has already been registered under REACH with the CLP classification and labeling or notified under CLP no further notification shall be submitted Substances classified as hazardous under CLP and placed on the market irrespective of the tonnage and Substances classified as hazardous under CLP and present in a mixture above the concentration limits specified in Annex I of CLP or as specified in the Dangerous Preparations Directive Directive 1999 45 EC which results in the classification of the mixture as hazardous and the mixture is placed on the market EU Not applicable Canada Ca 900 of the highest volume and most frequently transported chemicals IMO The hazardous chemicals classified a
165. SDS irSDS i iJAMP MSDS plus JAMP AIS x p 5e x O or x iWeb ASP O or x O or x i Copyright C 2012 2 1 1 2 2012 3 2 le rel C o C evan gt j _ ra r e mar wm a je sare a lt BERERURSEBBRCRGC 2 1 1 3 1 A I iJIS Z 7250 2005 JIS 2 7250
166. 1 Skin Corr 1B severe skin burns Skin Corr 1B severe skin burns Skin Corr 1B severe skin burns Skin Corr 1B severe skin burns X 77 1 8 20 Corrosive to dermal tissue and eye damage and eye damage and eye damage and eye damage H318 Causes conclusive but 8 3A Corrosive 1 BEAR OBER data lacking Eye Damage 1 serious eye not sufficient for s E rni to ocular tissue damage classification conclusive but conclusive but e not sufficient for not sufficient for classification classification H317 May cause H317 May cause H317 May cause H317 May cause 6 5B Contact 1 ss IIb es eic R Skin Sens 1 allergic skin Skin Sens 1 an allergic skin Skin Sens 1 an allergic skin Skin Sens 1 an allergic skin j i reaction reaction reaction reaction 58 5 conclusive but 6 6A Known or 2 EA n 2 data lacking inconclusive not sufficient for presumed nate classification human 6 7A Known or 6 1B 1B Carc 1B H350 May cause H350 May cause Carc 1B H350 May cause Carc 1B H350 May cause presumed cancer cancer cancer human carcinogens 6 8B Suspected Py Suspected conclusive but
167. Flammable aysa Liquids medum Z lt liquid and vapour liquid and vapour liquid and vapour liquid and vapour hazard 7 ze conclusive but conclusive but mu data lacking not sufficient for not sufficient for classification classification 8 conclusive but conclusive but ii aid data lacking not sufficient for not sufficient for classification classification 9 conclusive but conclusive but data lacking not sufficient for not sufficient for classification classification conclusive but conclusive but TTF 1 ata lacking not sufficient for not sufficient for ERE data lacki fficient fi fficient f classification classification 11 conclusive but conclusive but NY 77 ata lacking not sufficient for not sufficient for data lacki fficient f fficient f classification classification 12 conclusive but conclusive but 77 7J ata lacking not sufficient for not sufficient for data lacki fficient f fficient fi classification classification 13 Bett conclusive but conclusive but 7 ata lacking not sufficient for not sufficient for data lacki fficient fi fficient f classification classification 14
168. GHS OK GHS 2 16 A n GHS IR GHS GHS gt DE 2 2 4 2 GHS 4 GHS 4 17 2 4 GHS
169. 0 LCOS TL GO AY OMS EE OR eL IC 5 E 3 18 Q ERR OPERE 1 1 b 3 8 2 0 54 B K o Ct
170. 48712 I 2011 06 30 misis M HS GHS The amended list of GHS classification and labelling for 2011 06 28 RH SSGHS GHS SSS WZH HE SA el 2011 06 24 E amp EGHS FSS UN IZH HA EAO Cei E Abe 6 21 2011 06 21 ELE PRIRAIMAIAS lt 313 m 13 5 EPC N 2012 01 18 a Jae Ajo B 2011 10 27 TS EGHS a rain sien ETC HAEE 00 2011 10 11 z r ERU 2011 10 11 n eum 2011 09 20 re ae eee ee COPYRIGHT C 2010 NIER ALL RIGHTS RESERVED Q A GHS FSS GHS A gHA 8 windows Internet Explorer BAR C 7 http ncisniergokr ehs 4 X Goosle jj E RTV AIW Google v g155 we 4 A D A R GIO gt gt ne Google Google 9 HOME SITEMAP CONTACT US LOGIN MOY aura SES GHSA lIA GHS7Ig GHS H4 GHS BR H1 BS S GHS X IA 2 Fil Globally Harmonized System of Classification and Labelling of Chemicals GHS 29 82 H4 Apes mm 4 GHS
171. Alias CAS Hazard Hazard Pictogram aig amung Special Chinese Name English No Nd Category Description Note Flazamabl Gas H0 Catagory 1 HIEN Gus wader Gas under Pressure Pressure Arcata Tex c br Ligss md Gas EE Toxicite Dissolved Car Fk ge em ME BIEN Specthic Target Organ Systamic Toxicity Hal Rapanted Exposure agree gum Ligzz5ad Fei zi EAT NS 3 H360 H372 SAREE Rie H EN de eo SAWS Liu Qiang ChemCon Europe 2012 Madrid Spain 2012 3 5 40 2 4 2 1 79 06 1 EU REACH OO E zn conclusive but 1 RED data lacking not sufficient for classification 2 conclusive but data lacking not sufficient for A classification 3 conclusive but
172. CSEE Ministry of Health 3 Labour and Welfare Epichlarahydrin 1005 i CAS Na 105 89 8 UN Na 2023 000 OO gt ew SMA BERGE SIEIEO AB t GA x Ma Boras EERr if SCAR MATFSZrESLAM ERR ROCE BROAR BREEBOBtN ou SMBTEaABR FREER FR FROME RN bt2 tit G D COEC Kk oT TRES FROME XEEMCAS HERR MB Oto ob sn BAM Mss D t BHEBALTH lt Ck PRANCMEGARSe RA RE TMS P AtESIE RS oR BRE BRENT PRARRCHTAFH Mw ECRIEXSIE RRA FARA DS BAT Iu TERMES FTD Y FTATORSARt HARM WBA RRR eRATS6e OB LE g THC RM EK l em TRS zt
173. E C50i 1 LC50 EC50 mg l n G 1 n L E C50m L R C50 27 E Gi Ci Cj j 1 gt sona gt 0 1 gt EG Ci i Cj j NOEGi i NORC Gg NOEGj NOEC mg l n G j 1 n EqNOECm NORC 4 1 1000
174. YES mg lppm YES lt gt YES YES TRUE 0 mg 100 2 3 7 2 GHS GHS GHS
175. ESk 1 HER AE GHS IT 2 25 2 1 1 1 GHS 1 JIS iMSDS JIS Z 7250 2005 JIS_Z 7250 2010 E JIS 1 JIS Z 7251 2006 1 I I JIS 2 7251 2010 JIS WIS Z 7252 2009 2 O 3 4 inite IO or x I PRTR EZES i amp US EU d t X Ob BSD GHS 287 508 T
176. H317 May cause H317 May cause H317 May cause 6 5B Contact 1 D 1 Skin Sens 1 an allergic skin lan allergic skin Skin Sens 1 an allergic skin Skin Sens 1 an allergic skin 1 N sensitisers reaction reaction reaction reaction 5 T 6 6A Known or AN AN H340 May cause H340 May cause H340 May cause H340 May cause 1B 1B genetic defects J genetic defects genetic defects i genetic defects 27 presumed human 6 7A Known or 6 a a H350 cause H350 May cause presumed ZN 1B 1B Sare 1B cancer cancer human 7 H361f Suspected x 1B 1 1B Repr 2 of damaging fertility A carcinogens H372 Causes damage to organs 1 through anne prolonged or repeated 2 1 3 3 H319 Causes H319 Causes H319 Causes i 455 2A Eve Irrit 2A Eve Irrit 2 Eve Irrit 2 2 6 4A Irritating Irrit serious eye ye Irrit
177. SE EAQB In theory yes to a large extent in particular for physical hazards However for toxicity the criteria have changed over the time and substances have not been systematically reclassified on the basis of new criteria since the TDG Sub Committee considered that adoption of new criteria should not affect existing classified substances In addition some substances were classified a long time ago on the basis of human experience and human experience does not necessarily match the GHS criteria Some substances were also classified on the basis of test results and this classification may be sometimes more realistic than classification based on the application of some UN secretariat UN SCEGHS 20 INF 5 Response Country Organiz default classification systems allowed by the GHS e g use of pH values for corrosivity which can lead to over classification in the transport system Yes but does not include all of the health classes USA Question 12 In case if not all the chemicals on your list are classified in accordance with the GHS criteria how many GHS classified chemicals do you have listed Response Country Organiz Not applicable Argentina Not applicable Note There are 1200 pure substances on the ADG list of chemicals Australia which are classified according to the GHS for physical acute toxicity and environmental hazards The CLP list table 3 1 of Annex V
178. tesmer 0j LEO 42 63 02 LM IRD lt Z 7 2011 12 14 GHSS UT ROBERN UES ALLOA SHR SU fc MEUS 27259 De C0 0197 3 0 RS 28 IS OSCR AL 2011 12 14 2011 06 20 Q 2011 06 17 2011 06 14 6 SPAKE 1246 Lid 5 PDF27 42KB manaman J gosse fuz iz SUD ROI eret Do SIAR EUIS PERLA PDF 94KB FY PDF 187KB gt Y E 2 I NITE gt LPR gt HS GHS 338055 620923 S 0 S S3 CEDE ODMR html CCRIBI d S2 SRODIL2tI7rlli c55455 n Fcsis EF IMSOSOABIIW Tt SSMHERREYR OH LA VECH PA KF BS MEY ASL CHRIP HRN TST EJE HAT l Bb AT xd 1 18 ES EET T O FESMEG mOFE 5 5 2 460H3H5H E FS ond S 28 CF wi OF x r wass EN 50 29 3 1411 FU2DID 22 E 2 4 2D 02 xz JT ADT EN NES EN ET 23 068 0 6 7 OE 2 3 18 7 40 HE URS i POP
179. 20 20 lt C 200 ppm 6 C 50 50 C 250 X mg L 6 C 0 2 0 2 C 1 0 mg L 6 C 0 02 0 02 C 0 2 3 24 3 1 10 1 2 YE X43 1 E RA EEDA 1 a b 40 20 5 mm s 2
180. 20C 13 12 E 2 1 101 3kPa 20 2 ux 101 8kPa 20C EJ A x Pa i w gt 101 3kPa 20 3 ISO 10156 2010 n V 9 gt 1 7 uet a Wy V T
181. GHS GHS GHS GHS GHS 2 4 1 GHS GHS GHS 2 4 1 1 1 GHS 2 4 1 2 EU GHS
182. GHS GHS SDS JIS JIS Z 7253 2012 2 GHS 22 GHS GHS 127725 GHS GHS GHS GHS
183. P321 P307 P311 precautionary_statements precautionary statements 28 3 7 XA SR OG 23 do SBE precautionary_statements precautionary_statements precautionary_statements precautionary_statements precautionary_statements gt P321 precautionary_statements gt P321 precautionary_statements Jey precautionary_statements precautionary statements Ez Ji j P308 P313 P391 314 P362 P363 Hon lt
184. classification conclusive but not sufficient for Oxidising Solids classification conclusive but not sufficient for Organic Peroxides classification conclusive but not sufficient t Substances and Mixtures corrosive to Metals a classification Acute Toxicity Oral Acute Toxicity Dermal Acute Toxicity Inhalation Skin Corrosion Irritation Serious Eye Damage Eye Irritation Respiratory Sensitization Skin Sensitization Aspiration Hazard Germ Cell Mutagenicity Germ Cell Mutagenicity Carcinogenicity Carcinogenicity Reproductive Toxicity Reproductive Toxicity Specific Effect Route of exposure Effects on or via Lactation Specific target organ toxicity Single Specific target organ toxicity Single Specific target organ toxicity Repeated Specific target organ toxicity Repeated Human Health hazards Hazard Category Acute Tox 3 Acute Tox 3 Acute Tox 3 Skin Corr 1B Eye Dam 1 Skin Sens 1 Hazard Category Hazard Category Carc 1B Hazard Category Repr 2 Hazard Statement H301 H311 H331 H314 H318 H317 Hazard Statement Hazard Statement H350 Hazard Statement H361 Reduced male fertility Oral Hazard Category Hazard Category Hazard Statement Hazard Statement Reason for no Classification conclusive but not sufficient for classification conclusive but not sufficient f
185. data lacking data lacking data lacking data lacking data lacking data lacking data lacking data lacking data lacking data lacking data lacking 3 H226 Flammable liquid and vapour 29 Acute toxicity oral Acute Tox 3 H301 Toxic if swallowed Acute toxicity dermal Acute Tox 3 H311 Toxic in contact with skin Acute toxicity inhalation Acute Tox 3 H331 Toxic if inhaled Skin corrosion irritation Skin Corr 1B H314 Causes severe skin burns and eye damage Serious eye damage eye data lacking irritation Respiratory sensitization data lacking Skin sensitization Skin Sens 1 H317 May cause an allergic skin reaction Aspiration hazard data lacking Reproductive toxicity Reproductive toxicity data lacking Effects via lactation data lacking Germ cell mutagenicity Germ cell mutagenicity data lacking Carcinogenicity Carcinogenicity Carc 1B H350 May cause cancer state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard Route of exposure Oral Also caused via inhalation route Specific target organ toxicity single Specific target organ data lacking toxicity single Specific target organ toxicity repeated Specific target organ data lacking toxicity repeated Environmental hazards Hazardous to the aquatic data lacking environment acute short term Hazardous to the aquatic data lacking environment long term hazardous tothe ozone data
186. factors exposure limits IDLH chemical and physical properties measurement methods personal protection respirator recommendations symptoms and first aid Public Health Emergency Preparedness and Response CDC Chemical Agents List A Z http www bt cdc gov Agent agentlistchem asp Facts description and emergency response information from CDC related to the over eighty specific chemical agents by category and alphabetically Acute Exposure Guideline Levels AEGLs http www epa gov oppt aegl AEGLs are Environmental Protection Agency recommended criteria and are intended to describe the risk to humans resulting from once in a lifetime or rare exposure to airborne chemicals The National Advisory Committee for the Development of Acute Exposure Guideline Levels for Hazardous Substances AEGL Committee is involved in developing these guidelines to help both national and local authorities as well as private companies deal with emergencies involving spills or other catastrophic exposures International Chemical Safety Cards http www cdc gov niosh ipcs icstart html The International Chemical Safety Cards offer essential health and safety information on chemicals to promote their safe use They are intended to be used at the shop floor level by workers and employers in factories agriculture construction and other places of work being particularly useful in less developed areas and in small and medium size enterprises They a
187. serious eye ye Irrit serious eye 7 irritation irritation irritation il data lacking data lacking Tx N EA H350 May cause cancer H350 May cause cancer c 1B c 1B c 1B 6 8B Suspected human reproductive or developmental toxicants H361 Suspected of damaging fertility or the unborn child H361 Suspected of damaging fertility or the unborn child H361 Suspected of damaging fertility or the unborn child data lacking data lacking H372 Causes damage to organs through prolonged or repeated exposure H372 Causes damage to organs through prolonged or repeated H372 Causes damage to organs through 6 9A Toxic to 4M human target x 77 prolonged or repeated exposure organs or systems exposure 10 data lacking exposure e zl e ox o x ct 3 o o 9 S a4 ii UJ 5 Q Q Q gt 5 5 8 5 O O O x ct c u S 5 a 8 S E E E m x 3 a F 3 3 S zi i o 2 o x rm EU REACH Jm
188. www meti go jp policy chemical management int ghs classification html 2 http anzeninfo mhlw go jp anzen pg GHS MSD FND aspx 3 http www epa govt nz search databases Pages HSNO CCID aspx 4 http esis jrc ec europa eu index php PGM cla 5 http echa europa eu web guest information on chemicals cl inventory database 6 http echa europa eu web guest information on chemicals registered substances 7 http ncis nier go kr 8 SAWS Liu Qiang ChemCon Europe 2012 Madrid Spain 2012 3 5 1 GHS Fa Emish 82 amp ze sent ryz Ministry of Economy 9 METI Trade and Indust gt gt gt gt EFM RB CRORE gt gt GHS gt gt 01GHS OECD gt POP GHS MSDS RS Gn DR BEBE SEO ROGER rh DIU MSDS
189. 0 1mg l 3 NOEC ECx Simgl 26 NOEC ECx PRX Slmgl NOEC ECx 1mg 1 Gu 1 96 LCs 1 mg l 48 RCso 1 mgl XX 72 96 ErCso 1 mgl log Kow 4 BCF 500 2 96 LCso gt 1 mg 5 10 mg l 48 ECso PHX 21mg t 10 mg t 72 96 ErCso gt 1mg amp 510 mg H log Kowz4 BCF lt 500 NORC gt 1 mg l 3 96 LCso gt 10 mg lt S100 mg l 48 ECso PH gt 10 mg lt S100 mg t 72 96 ErCso OD gt 10 mgt
190. 3 1 5 1 m M 1 lA 1A a w 22 22 in w 1B 1B
191. 3 H226 H226 Acute Tox 3 H301 H301 Acute Tox 3 H311 H311 Skin Corr 1B H314 H314 Skin Sens 1 H317 H317 Eye Dam 1 H318 H318 Acute Tox 3 H331 H331 Carc 1B H350 H350 Repr 2 H361 H361 Danger 4 gt amp amp Flame Skull and crossbones Corrosion Health hazard 23 No available Data Physical and Chemical hazards Hazard Hazard f Classification Category Statement eason for no Classificatio conclusive but not sufficient for Explosives classification conclusive but not sufficient for Flammable Gases classification Flammable Aerosols data lacking conclusive but not sufficient for Oxidising Gases classification conclusive but not sufficient for Gases Under Presure classification Flammable Liquids Flam Liq 3 H226 rismmabel Solids conclusive but not sufficient for classification Self reactive Substances and Mixtures conclusive but not sufficient for classification SE conclusive but not sufficient for Pyrophoric Liquids classification conclusive but not sufficient for rophoric Solids Ass classification nclusiv n fficient for Self heating Substances and Mixtures P e but classification Substance and Mixtures which in contact with water emits conclusive but not sufficient for flammable gases classification s S conclusive but not sufficient for Oxidising Liquids i
192. 5 GHS 4 1 8 5 4 1 1 b G G 2 3 1 2 1 GHS GHS JIS Integrated Development Environment IDE 2
193. 7 2 3 4 _ 1 1 2 ISO 10156 2010 oxidizing power OP O n gt xC P i l 3253 i l 1 223 5 K B X i i Kk k Bk k n p Ci KkiXISO 10156 2010 Table 2 8 5 1
194. 8 7 2 lex GHS JIS 1 SDS GHS 2 D GHS D GHS SDS SDS
195. Sim E AH AAS IS E sme GHS 4 H P 1 6 FiP3O4 P340 ALAS Sols Che OME HSS PS064F2514F228 Se eR TAA maj FH Sie s my SA AS Bea l P308 P313 amp FEBS O FAAS PS upo a gt l P310 S4 HERE F311 54 Sens Sirm eae PFP 2 False HERE HE SIS P224 BEA IS IPS22 SLL 3 P PS33TP313 mp Xp Ede Ee Sl ure m 61 289 TE 38 7 P3B3 CHI AM Fe FiP3TO P3TB HA AD E 2088 2 BH ASML 38 GHS 5 H P 1 6 SH Storage P403 P233 B71 QP 171 FA Bol hela up P403 P235 27171 amp sl op PPa a zem m 71 Dean cal 501 aa 91 23 sU s ol ee el 39 8 Inventory of Hazardous Chemicals sample
196. Us Registered substances Regulations Chemical Substance Search Addressing Chemicals of cem Last updated 24th February Database contains 4 278 unique substances and contains information from 25 248 Information on Chemicals REACH Registration dossiers Pre registered substances 106 89 8 V 1 have read and EX I accept the Registered substances Enter search string a Chemical Name EC No Cas No etc Leave blank and press Search to view entire database Identified substances for registration in 2010 Substances identified Search results by industry to be registered by 31 May 2013 203 439 8 106 89 8 1 chloro 2 3 epoxypropane View 203 439 8 106 89 8 1 chloro 2 3 epoxypropane View Classification amp Labelling Inventory 1 chloro 2 3 epoxypropane re re the permission of the owner of the information as described in the ECHA Legal Notice General Information Classification and Labellin T3 Classification and Labelling Identification a GHS 4 Epichlorohydrin official Substance identification classification i chlara 2 3 epoxypropane a Epichlorohydrin se EC Number 203 439 8 classification EC Name 1 chloro Z 3 epoxypropane CAS Number 106 82 8 Molecular formula C3H5CIO 4 Epichlorohydrin IUPAC Name 2 chlorornethyllosziran Im Manufacture Use amp Exp Physical and chemical properties Environmental fate and pathways Ecotoxicological Informa
197. and positive interaction and proper coordination with all national international regulatory bodies concerned leads to effective implementation without unnecessary constraints UN secretariat At the time GHS was being developed many U S stakeholders preferred a criteria based system and not a new international classification body or list U S OSHA is undergoing rulemaking on aligning its hazard communication standard with the GHS and has requested feedback on this issue USA UN SCEGHS 20 INF 5 Question 23 If there was an international classification list of chemicals should it be for substances only or should it also include mixtures Response Should be for substances only Country Organiz AISE It should be for substances since there are many times more mixtures than substances and classification of mixtures can be expected to be more variable than for substances Regarding the latter classification of mixtures is more complex for example allowing the use of bridging principles to determine the classification of a mixture and can vary as a result of the use of options allowed under the GHS for mixture classification for example national authorities utilizing varying cut off options ACI The initial focus should be on substances The second step with the mixtures Argentina A national decision is yet to be made on this issue however in practical terms the priority should be on substa
198. available on the UN GHS website Priority should be given to substances with the highest volume and hazard Substances for which substantial test data already exists and there is consensus on the classification between countries would be the obvious first priority among these for inclusion in the international list IPPIC Restricted or controlled chemicals by international treaties would be the priorities Rotterdam and or Stockholm and or UN list of chemicals can be the way also Japan The list would include UN list of chemicals by UN TDG TLV list by ACGIH and carcinogens by IARC Korea The initial priority should be on chemicals of high hazard and or high risk as a result of the quantities used and the manner of use Thus chemicals on various existing international lists databases could be prioritised for initial GHS classification Suggested existing lists not necessarily in any order of priority would include Chemicals covered by WHO IPCS documents ICSCs EHCs CICADs Pesticides SDS particularly WHO Class 1 pesticides OECD HPV chemicals program Rotterdam Stockholm chemicals UNRTDG Dangerous Goods List IMDG Marine Pollutants New Zealand See comments above Note refer to question 17 Norway We find that priority would be to add High volume chemicals as well as CMR chemicals Serbia A starting point could be chemicals that are frequently transported and or manufactured used
199. code s Flam 3 Carc 1B x Acute Tox 3 I Acute Tox 3 lt Acute Tox 3 lt lt Skin Corr 1 344 F Skin Sens 1 44 Specific Concentration Limits and M Factors Concentration Classification Pictogram s o o Flame Skull and crossbones Health hazard Corrosion Regulation EC No 1272 2008 Annex VI Table 3 2 Classification Risk phrases Safety phrases Indication s of danger R10 45 53 T Carc Cat 2 R45 10 45 R23 24 25 23 24 25 C R34 34 R43 43 Concentration Limits Concentration Classification Cz196 T R23 24 25 0 1 1 20 21 22 Seveso Data Seveso Substance Main Seveso Category Other Seveso Categories Seveso Concentration Categories Yes 2 6 C z 10 2 596 C lt 10 96 2 1 C 596 2 0 196 2 C 196 Symbol s 18 5 EU ECHA CLP ECHA EUROPEAN CHEMICALS AGENCY Advanced search gt About Us Regulations Addressing Chemicals Information on Chemicals in our Life Support of Concern Chemicals C amp L Inventory database This database contains classification and labelling information on notified and registered substances received from manufacturers and importers It also Includes the list of Rarmonised classifications Search Classification and Labelling Inventory Search Criteria Substance Name e C Starts with Contains Matches exactly wit
200. for physical hazards acute toxicity and aquatic toxicity according to GHS The ADG Code effectively implements the GHS in Australia through land air and maritime transport regulations for those hazard classes covered in the transport sector Australia Yes the list is included in Annex VI Table 3 1 to the CLP Regulation EC No 1272 2008 the CLP list In addition in 2011 a Classification amp Labeling Inventory will be developed within the EU The Inventory 1s a database which will contain basic classification and labeling information on notified substances under the CLP Regulation and registered substances under the REACH Regulation Regulation EC No 1907 2006 The information will be submitted by manufacturers and importers in accordance with the CLP Regulation EU No Canada GESAMP the Joint Group of Experts on the Scientific Aspects of Marine Environmental Protection an advisory body to the UN system FAO IAEA IMO UN DOALOS UNEP UNESCO IOC UNIDO and WMO maintains an up to date peer reviewed list of the hazards to the environment and human health of ca 900 chemicals on behalf of the International Maritime Organisation IMO IMO Japan has the list The results of the classification approximately on 1 500 chemicals can be downloaded from the following site http www safe nite go jp english ghs_ index html Japan Yes Korea Yes Classifications of various chemicals are contained in a
201. in large amounts transport list OECD HP VC list rather than PIC POP chemicals that are already subject of existing international risk management measures Switzerland In our opinion first priority should be UN TDG amp GHS secondly WHO FAO recommended classification of pesticides and then Rotterdam and or Stockholm SE EAQB First the UN list of chemicals then pesticides and Rotterdam and or Stockholm SRICI Given the number of chemicals it would be unrealistic to think of an extensive list of chemicals at the very beginning Therefore it is suggested to start with the list of chemicals which are most commonly subject to international trade as listed in the UN Model Regulations on the Transport of Dangerous Goods The classification contained therein could be checked validated or corrected and completed as necessary This would already provide a very sound basis for harmonization Then the exercise could continue with substances which have already been assessed by countries or in particular the EU since they have already a rather extensive list intergovernmental organisations etc but still on the basis that the classification proposed would have to remain under the control of the GHS Sub Committee UN secretariat Potentially start with an existing list such as the International Chemical Safety Cards USA UN SCEGHS 20 INF 5 Part III Additional comments views received Comments from Organisation Cou
202. number of documents Issued pursuant to the Hazardous Substances and New Organisms Act 1996 HSNO Act notably the Hazardous Substances Chemicals Transfer Notice 2006 and the Hazardous Substances Dangerous Goods and Scheduled Toxic Substances Transfer Notice 2004 These lists are consolidated in the HSNO Chemical Classification Information Database CCID which is available on the ERMA New Zealand website at http www ermanz govt nz hs compliance chemicals html New Zealand Norway will implement the EU regulation on classification and labeling of substances and mixtures CLP See response from the EU commission Norway At this moment Serbia formally does not have a list of hazardous chemicals classified Serbia UN SCEGHS 20 INF 5 Response in terms of GHS but the list given in Annex 6 of EU Regulation 1272 2008 1s transposed in drafted national legislation which should be adopted in the second quarter of 2010 Country Organiz Switzerland is in the process of implementing GHS according to the Regulation EC No 1272 2008 CLP regulation Since 1 2 2009 Annex VI Tab 3 1 of the CLP regulation CLP list of harmonised classification and labelling of hazardous substances is legally binding in Switzerland to the same extend as in the EU for chemicals classified according to GHS CLP Questions 2 16 For Annex VI of Regulation EC Nr 1272 2008 see EU response Switzerland No SE EAQB Chin
203. should be on substances It is not easy to classify all mixtures since the components may different and variable SRICI unless the components and contents are fixed It could be for both substances and mixtures However given the amount of mixtures currently being placed on the market it might be advisable to focus at least at a first stage on the classification of substances UN secretariat Initially substances Question 24 If there was an international classification list of hazardous chemicals what would be the priorities on which chemicals to be added to that list Rotterdam and or Stockholm and or UN list of chemicals pesticides USA Response The priority should be those substances of high concern already identified in several countries regions Another way of developing such a list could be to extract the substances entries from the UN Model Regulations Dangerous Goods List as a basis these could then be reviewed on a hazard class basis starting with the most severe hazards updated as needed and other hazard classes categories 1 e those not covered by transport added as necessary It would be extremely useful if substances which have been evaluated and found to be not classified as hazardous according to GHS criteria could also be included in an international list Country Organiz AISE If there was an international classification list of hazardous chemicals it should be restricted
204. special interests politics and other factors have varying degrees of influence How would other countries industry resolve conflicts IPIECA This is certainly possible but a consensus process would be needed to ensure its acceptance in other countries An aggregation of existing country classification lists would be the preferred basis for an international list rather than the list from any single country Differing GHS implementations from country to country as a result of the building block approach are likely to yield different classifications for the same chemical which would have to be resolved and harmonised IPPIC It would be possible but not so easy It depends on the international consensus Japan Yes Korea Yes in principle as several such lists are already available if others wish to use them However it has been established that one of the problems with the lists that are now available is that there are inconsistencies between them in terms of the classifications given for the same chemicals The New Zealand CCID list is available on the internet but since the classifications on this are given in terms of the NZ descriptors of the GHS hazard categories it is not perhaps as readily useable as some other lists The list contained in Annex VI Table 3 1 to the EC CLP Regulation No 1272 2008 is perhaps the most likely to be used by other jurisdictions as there are several of these that already use or re
205. the SAICM objective with regard to knowledge and information on chemical substances However it will be a tremendous task therefore priorities e g limited to some hazard classes specific categories of substances like pesticides have to be set procedures have to be developed etc by taking into account existing activities e g dangerous goods list of the UN list of the International Agency for Research on Cancer Country Organiz Possibly provided that the list uses the same classification criteria adopted by the various sectors in Canada and that there is agreement on the datasets used Canada The need does not arise for GESAMP most of the new chemicals being submitted are not pure chemicals but substances and mixtures as transported IMO An international list of chemicals classified in terms of the GHS has the most value when it is accepted by all countries implementing the GHS The proliferation of national regional lists is contrary to harmonization See answers to Question 19 for attributes necessary to make an international list of chemicals classified in terms of the GHS useful The benefits of an international list of chemicals classified in terms of the GHS include supporting cost effective implementation avoiding duplication of effort and promoting harmonization consistency in classification These benefits apply to everyone and will be greater in countries without national GHS implementing legislation an
206. 2006 REACH 4 278 GHS CLP 9 Ex 5 GHS URL GHS 2 GHS EU iX CLP VI 3 5 CLP o 300 5 GHS EU R j 7 000 GHS 2 GHS 2 Jp EH
207. 2010 iJIS Z 7251 2006 JIS Z 7251 2010 JIS Z 7252 2009 inite ua B GHS EU US EU 67 548 E SDS 2 iJAMP MSDS plus JAMP AIS iWeb ASP 500 40007512 200 200 12 39505 r 80 1 505 2 1 2 1
208. 3 2 2 3 2 2 3 3 OO0 1 2 8 2 2 0 0 SEED CxHyOz 1600X 2X Y 2 Z 2 1 2 15
209. 331 H317 P308 P313 IF exposed or concerned Get medical advice attention required for H350 P305 P351 P338 IF IN EYES Rinse cautiously with water for several minutes Remove contact lenses if present and easy to do Continue rinsing required for H314 P303 P361 P353 IF ON SKIN or hair Rernove Take off immediately all contaminated clothing Rinse skin with water shower required for H226 H314 P301 P330 P331 IF SWALLOWED rinse mouth Do NOT induce vomiting required for H314 P304 P340 IF INHALED Remove victim to fresh air and keep at rest in a position comfortable for breathing required for H311 H314 PAOS3 P233 Store in a well ventilated place Keep container tightly closed P501 Dispose of contents container to 31 licensed perrnitted incinerator or other therrnal destruction device 7 2392 str epsr A Et eS eJUICE Windows Internet Explorer oo e http ncis nier eo kr M gt SUO 5 F EDO ATW DQ YD ALP Google yez gt DM ar Wr LIE A amp PrVO Grxrn Tem English ev IS rz EA qH A zat 2 DELE LI IRSE GHS GHS Aim 7 era 2011 07 08 nici Se I amp amp EGHS GHS SBS HE
210. A Corrosive to ocular tissue 91D fish Slightly harmful in the aquatic environment or are otherwise designed for biocidal action 9 10 crustacean Slightly harmful in the aquatic environment or are otherwise designed for biocidal action 9 1D other Slightly harmful in the aquatic environment or are otherwise designed for biocidal action 9 3A Very ecotoxic to terrestrial vertebrates 13 3 1C 6 1B oral 6 1B inhalation 5 1C dermal 6 5B contact 6 6A 6 7A Flashpoint Value 34 C Test Method Closed cup Boiling Point 116 11 C SPECIES Rat ENDPOINT LD50 VALUE 40 mg kg REFERENCE SOURCE Verschueren K Handbook of Environmental Data of Organic Chemicals 2nd ed New York NY Van Nostrand Reinhold Co 1983 612 PEER REVIEWED HSDB Inhalation Form vapour SPECIES Rabbit ENDPOINT LC50 VALUE 445 ppm 4 hr 21 68mg l REFERENCE SOURCE Verschueren K Handbook of Environmental Data of Organic Chemicals 2nd ed New York NY Van Nostrand Reinhold Co 1983 613 PEER REVIEWED HSDB SPECIES Mouse ENDPOINT LD50 VALUE 250 mg kg REFERENCE SOURCE Lewis R J Saxs Dangerous Properties of Industrial Materials 9th ed Volumes 1 3 New York NY Van Nostrand Reinhold 1996 1470 PEER REVIEWED HSDB SPECIES Guinea Pig RESULT Sensitising REFERENCE SOURCE Shell Nederland Chemie B V Hoogvliet Rotterdam 78 78 Rao K S Betso J E Olson R J 1981 collection of guinea pig sensitiza
211. AEREE AES SRE EDIDI V ch DE 2104088831 CERD 96 48 998 1966280 TR Fomin P Gig Sanit319 7 11 CDU HDTV EMO MRS GRE o EIC wo 3 Bie COPS ES 96 LC50 10600 e L AAU 2 28F1 82812 2002 18 68557 chus 3 SIR AEN DY BODIE TARE 67M TE d 77 505 logKow 0 45 PHYSPROPDatabase 2005 2 GHS gt HOME TAL OLA 22 TR 8 HSL o gt FS W Fats OP lv tE AA F lt A RE RMR SRM REO U Xs x HH 5 ARBAB SMe RAL SMCS Tt k SV SED D lt QA Ei G H Bis sb at ae Sait ERE ft gt
212. CID web page denotes the differences between the HSNO Act classification criteria and more recent versions of the GHS A process to update these regulations to reflect the 3rd Revised Edition of the GHS 2009 is underway see http www ermanz govt nz hs abouths ghscriteria html A guide on the application of the existing criteria to the classification of chemicals and mixtures is available at http www ermanz govt nz hs t amp c HSNOUGTC pdf New Zealand Norway will implement the EU regulation on classification and labeling of substances and mixtures CLP See response from the EU commission Norway Not relevant because of the reasons given previous responses question No 2 and 1 Serbia see remark regarding questions 2 16 in the answer to question 1 Switzerland China government has regulated dangerous chemicals using UN Model Regulations GB national standard 13690 2009 General Rule for Classification and Hazard Communication of Chemicals stipulates that chemicals shall be classified according to the 26 GHS classification standards which are already in place SE EAQB The Classification criteria are described for each of the hazard classes in the relevant chapters of Part 2 of the UN Model Regulations UN secretariat See links below Note refer to Part III of this document Question 9 Does the list contain the data on which the classifications were made USA Response Not applic
213. DG Subcommittee OECD Industry or Member States submit a proposal for a harmonized classification in case of different entries in the OECD inventory to the UN TDG Subcommittee The existing subgroups for physical chemical properties and health end environmental properties will evaluate the proposal The result will be a list containing of harmonized GHS classifications of substances to be used for transport and supply and use b Harmonization of the GHS classification for CMR properties of substances Member States or blocks of Member States will submit proposals for a GHS classification to the OECD who coordinates this exercise Industry can submit additional information where appropriate Evaluation should take place at the OECD level The result will be a harmonized classification of the CMR properties of the substance at the OECD level Member States or blocks of Member States will consider those classifications for implementation in their legislation or inventory c Harmonization of the GHS classification for non CMR properties of substances Industry or Member States submit proposals for a GHS classification to the OECD who coordinates this exercise Evaluation should take place at the OECD level The result will be a harmonized classification of non CMR properties of substances at the OECD level Member States or 39 UN SCEGHS 20 INF 5 40 blocks of Member States and Industry will consider those classifications for implem
214. I to CLP Regulation includes approximately 4000 EU entries covering approximately 8000 substances classified according to the GHS criteria Not applicable Canada All follow the GHS criteria IMO 1 500 chemicals Japan 11 377 chemicals are classified in accordance with the GHS Korea There are approximately 5400 GHS classified chemicals on the HSNO CCID As noted New Zealand above a number of these have been classified by translation from existing EU R phrase classifications Norway will implement the EU regulation on classification and labeling of substances Norway and mixtures CLP See response from the EU commission Nil Serbia see remark regarding questions 2 16 in the answer to question 1 Switzerland Not applicable SE EAQB About 1700 The Dangerous Goods list contains about 2700 entries but some of them correspond to articles out of the scope of the GHS hazards not subject to GHS radioactivity infectious and other miscellaneous hazards Furthermore the list includes a great number of generic or so called Not otherwise specified entries which are intended to let the industry to properly classify for transport substances which are not listed by name but which meet the classification criteria Only substances carried internationally in significant quantities are deemed to deserve an entry in the list UN secretariat Nil USA 19 UN SCEGHS 20 INF 5 20 C Area Resources Question 13 D
215. NEC GHS IT K AMH dE 24 4 2 4 2 1 4 2 2 4 2 3 4 2 4
216. Protection Agency EPCRA 302 304 313 emergency planning amp release reporting EPCRA Sections 302 amp 304 extremely hazardous substances subject to EPCRA s emergency planning amp release reporting regulations 40 CFR Part 355 http www access gpo gov nara cfr waisidx 01 40cfr355 01 html 41 UN SCEGHS 20 INF 5 EPCRA Section 313 toxic chemicals subject to EPCRA s Toxics Release Inventory 40 CFR Part 372 http www access gpo gov nara cfr waisidx 01 40cfr372 01 html http www epa gov emergencies content epcra index htm CERLCAS103 emergency release reporting regulations 40 CFR Part 302 hazardous substances http www access gpo gov nara cfr waisidx 01 40cfr302 01 html http www epa gov superfund policy release rq index htm CAAS112 r Chemical Accident Release Prevention Plan 40 CFR Part 68 AKA the risk management plan regulated substances http www epa gov emergencies content rmp index htm EPA s List of Lists This document cross references the lists of chemicals subject to EPCRA 88302 304 313 CERLCAS103 and CAAS112 r http yosemite epa gov oswer lol nsf homepage TSCASS b TSCA Inventory http www epa gov oppt newchems pubs invntory htm 42 2 4 1 2 GHS
217. SC classification guidelines These guidelines take into account factors other than the hazard of a chemical The Poisons Schedules contain cosmetics consumer s products human pharmaceuticals as well as some workplace chemicals such as veterinary medicines and pesticides Australia Yes until 01 June 2015 the EU will have a list of harmonised classifications based on the criteria of the old Directive 67 548 EEC This list is included in Annex VI Table 3 2 to the CLP Regulation EU No Canada GESAMP hazard profiles are GHS compatible the notation may be different but the criteria and the hazard banding are the same and are translated into classifications for Annex II of the MARPOL Convention covering the transport of bulk liquids and IMO UN SCEGHS 20 INF 5 Response gasses by sea Country Organiz The following laws have the list of hazardous chemicals however the classification criteria are different from the GHS Poisonous and Deleterious Substances Control Law 2 Fire Defence Law 3 Act on Confirmation etc of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof 4 Law Concerning the Examination and Regulation of Manufacture etc of Chemical Substances Industrial Safety and Health Law etc Yes Each ministry Ministry of Employment Labor Ministry of Environ
218. U Not applicable Canada The GESAMP composite list is up to date having been completely revised by a dedicated peer review group of GESAMP between 1998 and 2006 when the revised Annex II of MARPOL entered into force IMO Under consideration Some Ministries concerned already have draft results of classification of substances based on GHS criteria Japan Yes Korea No specific plans are set in place however after the classification criteria are updated in the HSNO regulations a number of the classifications currently assigned to chemicals on the CCID will need to be updated It is likely this will occur over a 5 year period 2011 2015 New Zealand Norway will implement the EU regulation on classification and labeling of substances and mixtures CLP See response from the EU commission Norway This question is not relevant for old list of poisons but the new List of classified substances will be made and amended by transposition from Annex 6 of Regulation 1272 2008 In this regards the New Law on Chemicals provides a legal basis for preparation and adoption of bylaw regulating implementation GHS The Law on chemicals has taken into account the existing EU regulations on classification labeling and packaging Directive 67 548 EEC Directive 1999 45 EC but also the new EU Regulation on GHS Regulation 1272 2008 which will be fully transposed into national legislation by adoption of corresponding
219. We are currently developing a list of substances in the context of EU CLP AISE implementation with a view to achieving consistency of classifications across our industry sector It is envisaged that the list would be available on request Not applicable ACI Not applicable Argentina Yes the two lists mentioned above are publicly available see question 5 Australia Yes EIGA Yes EU Not applicable Canada Yes GESAMP has given its working group a mandate to make this known to a much IMO wider group of potential users In promoting product stewardship the oil and gas industry has developed data on IPIECA recommended approaches for the classification of petroleum substances To encourage harmonized and consistent classification the regional petroleum industry associations are willing to share this information to assist in developing an international list of chemicals classified in terms of the GHS Downstream users of chemicals i e manufacturers of mixtures or their industry IPPIC associations typically do not maintain classification lists Such users generally rely on the classifications communicated by their raw material suppliers For paints or printing inks there are therefore no international or regional classification lists of substances used in these products Japan has already shared the list of classified substances according to the GHS Japan Yes Korea Yes It is already available on the ERMA New Zealand website at New Zea
220. a See below Note refer to question 2 UN secretariat Yes but it 1s transport specific only The transport list 1s not intended to be a comprehensive list of all materials that are regulated for transport Rather it is a list of appropriate proper shipping names some of which can cover a broad range of chemicals mixtures solutions The other sectors consumer workplace and environmental No Question 2 Does your country have a list of hazardous chemicals classified in terms of a system other than the GHS If so please specify system USA Response No Country Organiz Argentina Yes The Hazardous Substances Information System HSIS http hsis ascc gov au Default aspx is maintained by Safe Work Australia and contains classifications of industrial chemicals including pesticide active constituents Pharmaceutical chemicals are not included The origins of data for the HSIS are the previous EU classification which is reflected in the Australian Approved Criteria for Classifying Hazardous Chemicals These classifications are regularly updated on advice from Australian assessment agencies HSIS is updated regularly to reflect changes in EU s 30th Adaptation to Technical Progress to Directive 67 548 EEC Substances are also listed in the Standard for the Uniform Scheduling of Drugs and Poisons SUSDP classified according to legislated criteria contained in National Drugs and Poisons Scheduling Committee NDP
221. able Country Organiz Argentina No neither the SUSDP nor HSIS contain the data used on which the classification is based HSIS contains only the source of information and reference Note UN RTDG data considered by the Committee in the past is kept by the UN Secretariat and can be obtained on request The data on which Australian authorities based classification decisions such Poisons Schedule decisions are held by the responsible regulator Australia CLP list No it does not However for classifications made until mid 2007 the reports which summarise the conclusions for a classification are publicly available via the web site of the Joint Research Centre For classifications made after this period the documentation is available on ECHA s website subject to confidentiality claims EU UN SCEGHS 20 INF 5 Response Inventory No it does not However where a substance has been classified in some but not all hazard classes or differentiations an indication of whether this is due to lack of data inconclusive data or data which are conclusive although insufficient for classification should be indicated Country Organiz Not applicable Canada The list contains metadata in the form of banded ratings in order to protect confidential data the original data is maintained in hard copy and electronic form by IMO in London including confidential company information all hazard profiles can be rec
222. anage acute exposures resulting from chemical incidents The MMGs are intended to aid healthcare professionals involved in emergency response to effectively decontaminate patients protect themselves and others from contamination communicate with other involved personnel efficiently transport patients to a medical facility and provide competent medical evaluation and treatment to exposed persons Toxicology Interaction Profiles http www atsdr cdc gov interactionprofiles A series of documents called Interaction Profiles are being developed for certain priority mixtures that are of special concern to ATSDR The purpose of the Interaction Profile is to evaluate data on the toxicology of the whole priority mixture if available and on the joint toxic action of the chemicals in the mixture in order to recommend approaches for the exposure based assessment of the potential hazard to public health http www cdc gov niosh topics emres chemagent html search OSHA EPA Occupational Chemical Database OSHA and EPA jointly developed and maintain this database as a convenient reference for the occupational safety and health community This database compiles information from several government agencies and organizations https www osha gov web dep chemicaldata target EPA Information Although not comprehensive the information presented below contains lists of chemicals developed in response to regulatory requirements of the U S Environmental
223. anghai Research Institute of 345 East Yunling Road lgsh33 AT gmail com No Chemical Industry Testing Centre Shanghai P R China 200062 SE EAQB Zhenqian Song Shandong Entry Exit Inspection No 2 Zhongshan Road Szqciq AT 163 com No And Quarantine Bureau China Qingdao Shandong Province China 266002 SHNI 07 SHOHOS NN Country Organiz Name Organisation Contact information Email Confidential IMO Ken McDonald GESAMP c o International 4 Albert Embankment Kmcdonald AT imo org No Maritime Organisation London SE1 7SR UK IPIECA Derek Swick American Petroleum Institute for IPIECA Swickd AT api org No MECA 5th Floor 209 215 Blackfriars Road London SE1 8NL IPPIC Janice Robinson NTERNATIONAL PAINT amp 1500 Rhode Island Ave NW j robinson AT cepe org No PRINTING INK COUNCIL Washington DC 20005 IPPIC USA Japan Hiroshi Jonai Department of Medical care 1 8 14 Kandasurugadai Chiyoda Jonai AT medwel cst nihon u ac p No Welfare Engineering ku Graduate School of Science and Tokyo 100 8308 Technology Japan Nihon University Korea Hye Jin Lee Occupational Safety and 104 8 Munji Dong Hann1226 AT kosha net No Health Research Institute Yuseong Gu Korea Occupational Safety and Daejeon 305 380 Health Agency KOSHA New Zealand Peter Dawson Environmental Risk Management BP House peter dawson AT ermanz govt nz No Authority New Zealand 20 Customhouse Quay Wellington New Zealand Norway Christ
224. bian chemicals agency as institution responsible for chemicals management in Serbia as well as maintaining of List of classified substances transposed from Annex 6 of EU Regulation 1272 2008 This new list will be published in Serbian Official Gazette in the second quarter of 2010 As this list will be made and amended by simplified procedure e g transposition from EU Regulation there are enough resources for its maintaining Serbia see remark regarding questions 2 16 in the answer to question 1 Switzerland Yes Chinese state administration of work safety has worked on preparation of new edition of Dangerous chemicals List gt which will classify dangerous chemicals based on GHS SE EAQB Yes UN secretariat Nil USA UN SCEGHS 20 INF 5 Question 14 Do you have future plans set in place for the maintenance of the list Response Not applicable Country Organiz Argentina Yes Safe Work Australia intends to adopt the EU classification list in Table 3 2 in Annex VI of CLP as part of implementation of the GHS for workplace chemicals in 2012 and continue to update this list as Australian agencies classify pesticide active ingredients and other industrial chemicals However the list will be non mandatory and for guidance only Maintenance of the Poisons schedules for domestic chemicals including cosmetics is an ongoing process Australia See answer above Note refer to question 13 E
225. bylaw as well as the transitional periods for re classification and re labeling of chemicals according to this EU Regulation Serbia see remark regarding questions 2 16 in the answer to question 1 Switzerland Yes Draft of Dangerous chemicals List will release in late 2010 and will be amended and maintained in future SE EAQB This is done on a regular basis as the needs occur and on the basis of proposals by governments industry UN secretariat Nil USA 21 UN SCEGHS 20 INF 5 22 Question 15 Is the classification list to be expanded or developed Response Country Organiz Not applicable Argentina The GHS classification list of chemicals on HSIS will expand over time as the EU Australia under the CLP Regulations and Australia s Commonwealth government agencies classify veterinary medicines pesticide and other industrial chemicals as part of the authorisation processes The development of the list has been and will be an ongoing process EU Not applicable Canada It expands by ca 10 to 20 requests for new chemicals per year and an equal number of IMO queries from industry for modifications to profiles based on new data it is thus in a relatively stable phase following a decade of investment Being embedded as It is in the Convention implementation mechanism of a UN technical agency it is properly maintained Expanded Japan Yes Korea It is like
226. c and company confidential Lastly the same trade name may be applied to different mixtures supplied in different locations IPIECA For substances only but including complex substances which might otherwise be regarded as mixtures e g defined petroleum refinery streams mixed isomers of xylenes It is neither feasible nor appropriate for an international organisation to classify or list the many millions of mixtures on the international market Manufacturers should self classify their mixtures using the substance classifications and their own knowledge of the product IPPIC It would be impossible for mixtures Japan 35 UN SCEGHS 20 INF 5 36 Response Country Organiz Initial priority should be on substances and generalized mixtures having cas number Korea It should be for chemicals only ie not mixtures at least in the first instance New Zealand It is not realistic to make a list of mixtures since the composition of mixtures changes Norway constantly As first step list containing only substances will be satisfactory including of great Serbia number of mixtures produced all over the world would be very difficult but in further steps it could be useful to consider inclusion of mixtures The focus should be on substances for practical reasons large number of mixtures on Switzerland the markets with limited lifetime SE EAQB Mixtures are numerous and complicated so the initial focus
227. cation and labelling inventory will also be available post December 2010 Country Organiz AISE Among the national and regional implementation initiatives are efforts to publish and maintain lists of GHS classifications for individual chemicals e g New Zealand Japan EU Some intergovernmental groups are doing the same e g IPCS However it has been established that the lists now available are inconsistent with regard to their classifications of the same chemical for reasons referred to in response to question 17 Therefore no single existing classification list should be selected as the one definitive list to make available to all countries As an alternative to selecting one list a mechanism could be set up to facilitate awareness and access to any existing lists However recognizing the differences in information and procedures used to develop national and regional classifications there should be complete transparency associated with every classification as to the GHS criteria applied the information set that provided the basis for the classification the composition of test materials that the information sets apply to in order to judge their relevancy to a substance being classified and the expert judgments and weight of evidence evaluations applied to the classification decision Without transparency on these points the classifier would not know if the classification is relevant to their national or regional rules or t
228. ccording to the GHS are those which are required MSDS by the laws followed 1 Industrial Safety and Health Law 2 Poisonous and Deleterious Substances Control Law 3 Act on Confirmation etc of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof Japan The list includes industrial substances which is legally controlled or highly used among existing chemicals in Korea Korea Industrial chemicals dangerous goods as in UNRTDG including gases solvents petroleum substances components of commercial domestic and industrial products pesticide veterinary medicine and pharmaceutical active ingredients New Zealand Norway will implement the EU regulation on classification and labeling of substances and mixtures CLP See response from the EU commission Norway Not relevant because the list of poisons was not prepared according to criteria Serbia UN SCEGHS 20 INF 5 Response Country Organiz comparable with the GHS criteria Furthermore this List of poisons will be repelled in second quarter of 2010 and replaced by new List of classified substances which will be fully transposed from Annex 6 of EU Regulation 1272 2008 see remark regarding questions 2 16 in the answer to question 1 Switzerland Not applicable SE EAQB Most types of GHS classified chemicals provided that they are most commonly transported and except t
229. contained in the Hazardous Substances Classification Regulations 2001 These criteria align with the early version 2000 of the GHS These chemicals were classified using the best data available to ERMA New Zealand at the time of classification New chemicals post 2001 are subject to an application process by industry to ERMA NZ which involves the classification against these same early GHS criteria The applicant provides the classification of the chemical in the application and this 1s reviewed by ERMA New Zealand Applications are open for public consultation Information on the application process can be found at http www ermanz govt nz hs applications release html New Zealand Norway will implement the EU regulation on classification and labeling of substances and mixtures CLP See response from the EU commission Norway Not relevant because of the reasons given previous responses question No 2 and 1 Serbia see remark regarding questions 2 16 in the answer to question 1 Switzerland Currently chemicals are classified according to their intrinsic hazards defined by TDG criteria and will be classified by GHS SE EAQB Chemicals are classified according to their intrinsic hazards defined by GHS criteria to the extent these criteria are relevant in the transport context Classification is made on the basis of consideration of data submitted to the Committee of Experts by governments intergovernmental an
230. covery mating at 50 ppm increase in preimplantation losses exposure matings at 25 and 4 EU ECHA CLP GHS European Commission Institute for Health and Consumer Prote ction European Commission gt JRC gt IHCP gt ESIS lt POLIT a Select an item w 3 1 l 3 UU U I Search Annex V gt e Maiore none tL LOHN k ri Download Annex VI 4136 16 01 2012 3 1 837 kB able 4136 18 01 2012 2 751 KB 16 CLP GHS European Commission CLP GHS Language EN v Index number _ EC number CAS number 106 89 8 Substance Name R2 Risk Phrases i To select more than one code keep the CTRL key R5 R6 EUH059 Hazard Statement Codes To select more than one code keep the CTRL key H203 H220 v At vw 17 Details on Substances Classified in Annex VI to Regulation EC No 1272 2008 CLP Annex VI General Information Table 3 1 Table 3 2 f Index number ATP inserted ATP updated 603 026 00 6 CLPOO 1 203 439 8 106 89 8 epichlorhydrin 1 chloro 2 3 epoxypropane Regulation EC No 1272 2008 Annex VI Table 3 1 Labelling Hazard Class Hazard Statement Pictogram Hazard Statement Suppl Hazard and Category Code s Code s Signal Word Code s Code s statement
231. d international organizations UN secretariat Not Applicable USA Question 8 Can you provide a reference for the applied classification criteria Response Country Organiz Not applicable Argentina Yes Australian Approved Criteria for Classifying Hazardous Substances NOHSC Australia 1008 2004 http www safeworkaustralia gov au NR rdonlyres C3F31984 D009 4 5E ASBA F6CD5638A7EF 0 approved criteria NOHSC1008 2004 pdf and NDPSC Guidelines http www tga gov au ndpsc ndpscg pdf The applied classification criteria are laid down in Annex I to the CLP Regulation EU which is based on the GHS Not applicable Canada Hazard profiles are prepared according to GESAMP Reports amp Studies 64 2002 IMO available from www gesamp org 13 UN SCEGHS 20 INF 5 14 Response Concerning the GHS classification Yes The JIS Japan Industrial Standards for GHS classification and Classification Manual have been published Concerning substances regulated in the laws Case by case Country Organiz Japan Yes the guideline is available in from http oshri kosha or kr Korea The classification criteria are contained in the Hazardous Substances Classification Regulations 2001 http www legislation govt nz regulation public 2001 01 13 latest DLM33833 html which are issued under the HSNO Act The criteria in these regulations are based on the proposals for the GHS in 2000 A table on the C
232. d intraperitoneal injection it gave negative results after continuous skin painting but was active as an initiator of skin It produced local sarcomas after subcutaneous injection ref 6 and was active in a mouse lung tumour bioassay by intraperitoneal injection ref 7 1 Enterline P E 1982 Importance of sequential exposure in the production of epichlorohydrin and isopropanol Ann N Y Acad Sci 381 344 349 2 Tassignon J P Bos G D Craigen A A Jacquet B Kueng H L Lanouziere Simon C amp Pierre C 1983 Mortality in an European cohort occupationally exposed to epichlorohydrin ECH Int Arch occup environ Health 51 325 336 3 Konishi Y Kawabata A Denda A Ikeda T Katada H Maruyama amp Higashiguchi R 1980 Forestomach tumors induced by orally administered epichlorohydrin in male Wistar rats Gann 71 922 923 4 Wester P W van der Heijden C A Bisschop A amp van Esch G J 1985 Carcinogenicity study with epichlorohydrin CEP by gavage in rats Toxicology 36 325 339 5 Laskin S Sellakumar A R Kuschner M Nelson N La Mendola S Rusch G M Katz G V N C amp Albert R E 1980 Inhalation carcinogenicity of epichlorohydrin in noninbred Sprague Dawley rats J natl Cancer Inst 65 751 757 5 IARC Monographs 11 131 139 1976 7 Stoner G D Conran P B Greisiger E A Stober J Morgan M amp Pereira M A 1986 Comparison of two routes of che
233. d regulation IPIECA A unanimous YES Especially useful or even necessary for small to medium businesses which lack resources to devote to classification and or for those operating in more than one country region Comment to be useful the classifications must be based on multiple datasets and be universally accepted IPPIC It must be very helpful and useful when content of the list is proved to be adequately reliable and reasonable for example by disclosing the data or information on which the classifications were made Japan Yes it will be useful and correspond to original purpose of the GHS Korea Yes New Zealand Norway take part in the EU work related to the harmonised list of classification in Annex VI of the CLP regulation and support this work This ECHA inventory list will be available on internet for all users from all countries Since this list is based on the GHS criteria suppliers from developed and less developed countries can use this list in their work with classification and labelling The idea of an international list of chemicals at the GHS level might be useful in theory and supports the idea of GHS However this will require a lot of resources to establish and maintain Norway is therefore reluctant to support an establishment at GHS level at this stage since this will be complicated need a lot of resources and be very time consuming If additional resources are available we wou
234. e an appropriate body to co ordinate this as for International Chemical Safety Cards IPPIC Relevant UN bodies and OECD should work together cooperatively Japan Working group under UN GHS sub committee including experts in TDG IARC etc needs to be organized Korea This would require a large commitment of resources Ideally it could be maintained by the UNSCEGHS and its Secretariat in a similar way to the list of Dangerous Goods in the UNRTDG Model Regulations However the process for development and maintenance and who and where the work would be done would need quite a bit of thought work and resources Another possible option would be for the OECD eChemPortal to be developed into a database of internationally agreed GHS classified chemicals rather than as it is at present as just a portal to other databases some of which contain GHS classifications New Zealand See comments above Note refer to question 17 Norway One of UN organisations cooperating with countries that have the lists of chemicals classified in terms of the GHS The harmonisation of classification and labelling of substances and the classification and labelling inventory given in Title V of EU Regulation 1272 2008 could be used as model for development of such list Serbia As the development and maintenance of a classification list is an enormous task it should be carefully evaluated whether existing groups of experts working on ha
235. e with the Hazardous Substances and New Organisms HSNO regulations The information on the classification of chemicals will help with classifying formulated products It may also be useful for preparing labels and safety data sheets For more information about the CCID Whatis the CCID For wildcard searches please add 96 after the substance name Search the CCID CAS Number w 106 89 8 12 Oxirane chloromethyl HSNO Cas Number 106 89 8 Synonyms Chloromethyl ethylene oxide 1 2 Epoxy 3 chloropropane 1 Chloro 2 3 epoxypropane 2 Chloromethyl oxirane 2 3 Epoxypropyl chloride 3 Chloro 1 2 epoxypropane 3 Chloro 1 2 propylene oxide 3 Chloropropene 1 2 oxide 3 Chloropropylene oxide Chloromethyloxirane Chloropropylene oxide Epichlorhydrin Epichlorohydrin Glycerol epichlorhydrin Glycerol epichlorohydrin Glycidyl chloride Propane 1 chloro 2 3 epoxy Molecular Weight 92 5 Relative Density Water Solubility mg l 65800 Approval Number HSR000977 UN Class 6 1 PGII UN Number 2023 Classification 3 1C Flammable Liquids medium hazard 6 1B oral Acutely toxic 6 1B inhalation Acutely toxic 6 1C dermal Acutely toxic 6 5B contact Contact sensitisers 6 6A Known or presumed human mutagens 6 7A Known or presumed human carcinogens 6 8B Suspected human reproductive or developmental toxicants 6 9B inhalation Harmful to human target organs or systems 8 2C Corrosive to dermal tissue 8 3
236. ed will be reviewed by annual plan As above Note refer to questions 14 15 New Zealand Norway will implement the EU regulation on classification and labeling of substances Norway and mixtures CLP See response from the EU commission The new List of Classified Substances will be fully transposed from the Annex VI to Serbia EU Regulation 1272 2008 If new substances are added into Annex VI to EU Regulation 1272 2008 it will be added into List of classified substances see remark regarding questions 2 16 in the answer to question 1 Switzerland The old edition of Dangerous chemicals List gt is based on UN Model Regulations SE EAQB focus on acute physics dangerous category The new edition of Dangerous chemicals List will be based GHS and will add healthy environment dangerous category into Following consideration of data submitted to the Committee of Experts by governments intergovernmental and international organizations UN secretariat Nil USA 23 UN SCEGHS 20 INF 5 24 D Area For the future discussions on classification lists Question 17 Would you find an international list of chemicals classified in terms of the GHS useful Response An international list database of GHS classifications for substances would be a useful resource for companies particularly those with limited resources e g small enterprises but the use of such a list should be voluntary However it is reco
237. edures and during future processes to maintain such a list there would need to be transparency including the opportunity for stakeholder review and comment on the data used in the classification and the decision rationales as well as a dispute resolution process Any effort to develop an international list of classifications should also recognize existing internationally agreed classifications and not duplicate past or current work to develop and maintain classifications If work were to go forward on the development of an international list given the large number of substances in commerce a process for prioritizing the work would be critical ACI The initial focus should be in the International Chemical Safety Cards developed through the International Programme on Chemical Safety Argentina If agreed that a list should be developed an internationally recognised body such as the UNSCEGHS or OECD could develop the list but processes and data used to develop the list must be agreed upon by all stakeholders Australia It should be done at the level ofthe UNSC GHS in a similar way it has been done and still is being done for the dangerous goods list by the UNSC TDG EIGA A possible model would be for the list to be maintained overall by the UNSCEGHS with technical input from OECD IARC transport sub committee The list could be an Annex to GHS EU The initial focus should be in the International Chemical Saf
238. egional national sectoral lists such as the TDG list IARC list or the EU CLP list and inventory In addition in existing lists there are differences in classification of the same chemicals by reason of different data used for classification and different approach for evaluation of this data Therefore the data which were used as a basis for classification should be collected and comprised EU UN SCEGHS 20 INF 5 Response Possibly provided that the list uses the same classification criteria adopted by the various sectors in Canada and that there is agreement on the datasets used Country Organiz Canada Politically probably not the GESAMP list has the advantage that it is international in application peer reviewed open to comment and well maintained if little known outside the shipping world IMO Most countries regions organizations already make their lists readily available South Korea has yet to make their list available outside of South Korea The UNSCEGHS could facilitate access to this classification information by providing links or copies of the various lists on the UN GHS website This would be a helpful interim step Before even developing the list the criteria for inclusion of chemicals on the list should be first agreed The difficulty in using a specific list is the ability of global stakeholders to comment and to provide input data on specific listed chemicals Depending on the list
239. ent for not sufficient for environment or classification classification are otherwise designed for biocidal action conclusive but conclusive but data lacking not sufficient for not sufficient wl classification classification conclusive but conclusive but data lacking not sufficient for not sufficient for classification classification 2 4 2 4 CLP 106 89 8 x S sS or rz Flam Lig 3 H26 o O O O o O o AcuteTox 3 H301 o o o L o T o L o o o o o o Oo AcuteTox 3 H311 O O O O o AcuteTox 3 H331 o o o L o LT o L o o o o o o la SknCor 1B H314 O O O O O O Eyepam 1 Hoe J I J Skin Sens 1 Hai7 o o Baso J j j j j _ Car iB a Hs50 Rer2 met j jJ j j j REACHESRCARHEHB wv vv p p p s 999 no nv j 45 29 26 1 4 3 1 1 3 il i CLP VI 3 1
240. entation in their legislation own inventory or self classification Comments from Organisation Country OSHA USA None of the databases or lists presented below are GHS compliant National Toxicological Program NTP provides a report on potential carcinogens Criteria for these chemicals can be found at http ntp niehs nih gov index cfm objectid 03C9CE38 E5CD EE56 D21B94351DBC8FC3 National Institute of Occupation Safety and Health NIOSH provides a links of publicly available chemical database The following databases provide detailed information on a variety of chemical agents associated with emergency response including information on how to protect workers from exposures to these agents The Emergency Response Safety and Health Database ERSH DB http www cdc gov niosh ershdb Developed by NIOSH for the emergency response community the ERSH DB contains accurate and concise information on high priority chemical biological and radiological agents that could be encountered by personnel responding to a terrorist event NIOSH Pocket Guide to Chemical Hazards http www cdc gov niosh npg default html DHHS NIOSH Publication No 2005 149The Pocket Guide is a source of general industrial hygiene information on several hundred chemicals classes found in the work environment Key data provided for each chemical substance includes name including synonyms trade names structure formula CAS RTECS Numbers DOT ID conversion
241. erials currently listed by name in the UN Orange Book have NOT been reviewed against the new GHS criteria and their classifications updated The International Chemical Safety Cards ICSC are peer reviewed but it is by a select group of experts that represent limited input There is no mechanism for input or conflict resolution The ICSC are not updated frequently as new data become available The data to support the classifications or explaining the rationale behind the classifications is not available There is no mention of any impurities in the chemicals Since many countries have not yet implemented the GHS for pesticides it would seem that pesticides would not be a first priority for an international classification list of hazardous chemicals Since at least one major country is not planning on implementing environmental hazards in the near future it doesn t seem to make sense to have the Stockholm Convention Persistent Organic Pollutants as a priority for an international classification list It is recognized that there is an existing project on classifying the chemicals in the Rotterdam Convention Since these chemicals pesticides have been banned or severely restricted such a list would have only limited usefulness and impact The cost benefit IPIECA 37 UN SCEGHS 20 INF 5 38 Response Country Organiz of developing such a list should be considered However it could be useful to make these classifications
242. es such as IMO UNIDO ILO etc Developing countries setting up Chemicals control for the first time and not wishing to repeat classifications Harmonization and manufacturers guidance IMO An international list of chemicals classified in terms of the GHS is useful to governments to avoid duplication of effort in creating national systems to facilitate international trade in chemicals to promote harmonization consistency and to reduce the costs of enforcement Also an international list of chemicals classified in terms of IPIECA UN SCEGHS 20 INF 5 Response the GHS will improve safety for workers and others through consistent and harmonized communications on chemical hazards and practices to follow for safe handling and use An international list of chemicals classified in terms of the GHS is useful to manufacturers to promote cost effective implementation to facilitate international trade in chemicals in applying expert systems resulting in maximizing expert resources and minimizing labour and costs to facilitate electronic transmission systems with international scope to promote harmonization consistency to expand the use of training programs on health and safety to improve the credibility of communication and to reduce laboratory testing on animals Furthermore an international list of chemicals classified in terms of the GHS will greatly benefit countries without national GHS implementing legislation and re
243. ety Cards developed through the International Programme on Chemical Safety These cards are peer reviewed Canada No comment IMO An expert group should be formed under the UNSCEGHS structure to develop the international list This is an especially challenging issue as developing and maintaining a list is very resource intensive Perhaps there are opportunities to share the burden In order to promote the overarching GHS goals of global harmonization and facilitation of trade it is essential that any international list of chemicals classified in terms of the GHS be based on a rigorous evidence based scientific process to be defined in advance and applied globally contain the data to support the classifications or a section explaining the rationale behind the classifications IPIECA UN SCEGHS 20 INF 5 Response ensure accuracy by including impurities and CAS numbers for the chemicals include mechanisms for updating as new evidence based science becomes available have defined criteria for source data provide a conflict resolution mechanism and have provisions for stakeholder input data Country Organiz A group under the auspices of an international organisation such as UN or OECD is regarded as most appropriate Governments should provide resources to develop and maintain the list as part of their GHS implementation commitment Some suggested that ILO SafeWork would b
244. gnised that some countries regions may choose to mandate the classification of certain substances Country Organiz AISE Many industries and governments are engaged in implementing the GHS which is a resource intensive process Adding to this burden by asking the commitment of resources to develop an international list of classified chemicals could be expected to divert resources away from implementation initiatives at the national and regional levels thereby delaying implementation The process of developing such a list would be burdensome because it should address factors that contribute to the current state of different classifications and establish procedures that address the sources of those differences including 1 Differences in how countries are implementing the options incorporated in the GHS 2 Challenges in linking chemicals to relevant sets of data Datasets that nominally appear to be relevant to the same substance under the definition of substance under the GHS may actually apply to different substances when the additives impurities and solvents are considered That will likely require knowledge of the processes used to produce a substance which may not be readily available 3 Differences in how classifiers apply expert judgement and weight of evidence evaluations Until the technical issues are resolved creation of a single global list can t be done Even with technical issues resolved consideration of produci
245. gulation and countries lacking the capacity to implement the GHS Country Organiz Use is foreseen equally by both manufacturers suppliers users of chemicals to classify their products and government regulators to ensure harmonisation between territories IPPIC Firstly manufactures of chemicals and articles including chemicals secondly government ministries concerned Japan It s helpful to government manufacturers NGO union and especially developing countries Korea Manufacturers and suppliers of chemicals and chemical products primarily for the classification of mixtures for the purposes of producing labels and SDS Also regulatory agencies for the purposes of international harmonisation and border control and enforcement authorities New Zealand See comments above Note refer to question 17 Norway An international list of chemicals classified in terms of the GHS could be useful as list that Serbian manufacturers and exporters as well as importers could use as reference for classification of substances which are not on EU market and are not given in List of classified substances transposed from Annex 6 of EU Regulation 1272 2008 but the classification must be done according to the rules given in national legislation which is harmonised with EU legislation in this area Serbia Industry manufacturers of substances formulators of mixtures suppliers of chemical products enterp
246. h Other Identifier oe Only Harmonised C amp L e Classification Details Hazard Class and Category Code s Hazard Statement Code s Flam Gas 1 H200 Flam Gas 2 H201 5 Physical hazards Flam Liq 1 H202 Flam Liq 2 H203 M Acute Tox 1 H300 Acute Tox 2 H301 Health Hazards Acute Tox 3 H302 Acute Tox 4 4 H303 Aquatic Acute 1 EUHOS9 Aquatic Acute 2 H400 Environmental Hazards Aquatic Acute 3 H401 Aquatic Chronic 1 H402 You may select one or more of the above values by using the Control CTRL key In order to perform a search you need to read through and agree to this legal disclaimer Search Clear Summary Of Classification and Labelling Harmonised classification Annex VI of Regulation EC No 1272 2008 CLP Regulation General Information 203 439 8 106 89 8 603 026 00 6 epichlorhydrin 1 chloro 2 3 epoxypropane ATP Inserted Updated CLPOO CLP Classification Table 3 1 Flam Liq 3 H226 H226 GHS02 GHS06 Acute Tox 3 H301 H301 GHS05 Acute Tox 3 H311 H311 GHS08 Dar Skin Corr 1B H314 H314 Skin Sens 1 H317 H317 Acute Tox 3 H331 H331 Carc 1B H350 H350 Danger lt e e Flame Skull and crossbones Corrosion Health hazard 20 Notified classification and labelling General Information 1 203 439 8 106 89 8 1 chloro 2 3 epoxypropa
247. he CLP Regulation However the CLP Regulation does not include all GHS categories For example the CLP Regulation does not cover categories such as acute toxicity cat 5 aspiration hazard cat 2 and aquatic toxicity cat 2 and 3 EU Not applicable Canada They are rated according to GHS criteria IMO Yes As for some laws concerned it s under consideration to accord criteria of substances regulated by the laws to GHS criteria Japan Yes Korea Yes but as discussed above the classification criteria used are essentially those contained in the original 2003 version of the GHS The exception is the criteria for flammable aerosols which were taken from the UNRTDG 11th revised edition 1999 The classifications contained in the CCID are denoted by the New Zealand alphanumeric codes for identifying the GHS classification categories However a table is available on the CCID web page that provides correlation of these with the GHS categories New Zealand Norway will implement the EU regulation on classification and labeling of substances and mixtures CLP See response from the EU commission Norway No but it is not relevant because the List of poisons will be repelled very soon and replaced by new List of classified substances fully transposed from Annex 6 of EU Regulation 1272 2008 Serbia see remark regarding questions 2 16 in the answer to question 1 Switzerland SE EAQB China
248. he substance they are trying to classify or if the dataset is consistent with the dataset they had available locally In addition a mechanism for users of such a list to offer additional information on a substance or its classification should be provided Considering the points above it may be more valuable for classifiers to have access to the data underlying existing classifications than the classifications themselves ACI Yes if the list uses the same classification criteria and if there is agreement on the databases used Argentina Yes in theory as that 1s the approach currently taken in the workplace sector in Australia which relies on EU classifications However in practice it would be highly unlikely as all countries would need to agree on the data and processes used to develop the list Australia We suggest to start with the list that will be made available by the European Chemical Agency ECHA within a few months after the deadline for the phase 1 or the registration of 21000T y chemicals under REACH The test data that supported the GHS classification will be made public and be open for checking and challenge by other regional authorities EIGA Having in mind the need develop priorities to set up an international list of classified substances see above it may be more realistic to aim for an independent list under the ownership of the UNSCEGHS taking into account experience gained in developing other r
249. hose possessing hazardous properties that do not require specific transport conditions The hazards covered are all physical hazards with some low hazard categories excepted in a few cases acute toxicity Cat 1 2 and 3 corrosivity and hazardous to the aquatic environment Acute 1 and Chronic 1 and 2 For transport in sea going or inland navigation chemical tankers Acute 1 2 and 3 and Chronic 1 2 and 3 Hazards to the environment are not indicated if the substance possesses other hazards subject to transport regulations There are nevertheless identified in the IMDG Code list marine pollutants Hazards not relevant to the transport regulatory system are not indicated UN secretariat For transportation only USA 17 UN SCEGHS 20 INF 5 18 Question 11 Are the chemicals on the list classified in accordance with the GHS classification criteria Response Not applicable Country Organiz Argentina Currently workplace chemicals are classified according to the Australian Approved Criteria for Classifying Hazardous Substances NOHSC 1008 2004 which is based on pre GHS EU classification scheme Substances listed in the Standard for the Uniform Scheduling of Drugs and Poisons SUSDP are classified according to legislated criteria contained in National Drugs and Poisons Scheduling Committee NDPSC classification guidelines Australia Yes in so far as the GHS criteria are included in Annex I to t
250. ine Bjorge Climate and Pollution Agency Str msveien 96 Christine bjorge AT klifino No Oslo N 0032 Norway SANI 0C SHOOS NA Country Organiz Name Organisation Contact information Email Confidential Serbia Katarina Krinulovic Serbian chemicals agency Omladinskih brigada 1 katarina krinulovic AT ekoplan gov rs No 11070 Novi Beograd Serbia Switzerland Markus Hoffmann Federal Office of Public Health CH 3003 Bern markus hofmann AT bag admin ch No Switzerland UN secretariat Rosa Garcia Couto United Nations Economic Palais des Nations 8 14 Avenue de rosa garcia couto AT unece org No Commission for Europe la Paix UNECE Geneva 10 CH 1211 Transport Division Dangerous Goods and Special Cargoes Switzerland Section Secretariat of the ECOSOC Sub Committee of Experts on the GHS USA Maureen Ruskin OSHA 200 Constitution Avenue Ruskin Maureen AT dol gov No Washington DC United States SHNI 07 SHOHOS NN UN SCEGHS 20 INF 5 Part Survey responses submitted by the GHS Sub Committee experts on the classification lists of hazardous chemicals Area Organisation Question 1 Does your country have a list of hazardous chemicals classified in terms of the GHS Response No Country Organiz Argentina Partially yes The Australian Dangerous Goods ADG List aligned with UN Model Regulations on Transport of Dangerous Goods rev15 contains classifications
251. ional regional or other available lists or databases of classifications for individual chemicals might provide useful references for classifiers and labelers particularly those with fewer resources e g small enterprises However as countries move forward with GHS implementation the objective of self classification stated in the GHS framework should be maintained Therefore use of such lists should be voluntary However all classifiers may find value having access to data on substances that can be used to decide on a classification for a substance ACI Developing countries countries with economies in transition specialy small and medium enterprises Argentina This would depend on the type of list developed and its purpose At present lists are used by manufacturers and suppliers of chemicals and chemical products for compliance with their duties to classify under hazardous chemicals regulations primarily for the purposes of producing labels and SDS Australia s HSIS is also used for compliance and enforcement purposes by safety regulatory authorities Australia The suppliers of chemicals EIGA The primary group of users would be suppliers and users of substances and authorities in developed and developing countries as well as the packaging and transport sectors EU Developing countries countries with economies in transition industry particularly small and medium enterprises Canada UN agenci
252. is included in Part 3 Chapter 3 2 of the UN Model Regulations on the Transport of Dangerous Goods and is available in the 6 UN official languages English French Russian Spanish Arabic and Chinese Country Organiz UN secretariat Yes USA Question 6 Is it a legally binding list of classifications Response Country Organiz Not applicable Argentina Yes both lists are given legal effect by Australia s state and territory jurisdictions Note Australia however that Safe Work Australia intends HSIS to be merely advisory when the GHS 1s implemented in 2012 for workplace chemicals for the reason that it is the duty under workplace chemical laws of manufacturers and suppliers to classify chemicals correctly and the GHS is a self classification system The CLP list is legally binding The Inventory is not legally binding EU Not applicable Canada The hazard profiles are used as the basis for all IMO Pollution category ship type and IMO tank type classifications plus the assignment of carriage conditions as an integral part of Annex II of the MARPOL Convention as implemented through the IBC Code There are two types of list one is legally binding another not binding Japan The classification results according to the GHS are not legally binding No it s not mandatory for information only Korea Yes where the classifications are given for a chemical that has an approval under the New Zeala
253. isation are listed in the alphabetical order in the next column http www unece org trans main dgdb dgsubc4 c4inf20 html UN SCEGHS 20 INF 5 Annex Part I Submissions received Country Organiz Name Organisation Contact information Email Confidential ACI USA Richard Sedlak American Cleaning Institute 1331 L Street NW Suite 650 rsedlak AT cleaninginstitute org No formerly The Soap and Washington DC 20005 Detergent Association AISE Wendy Cameron A I S E International Avenue Herrmann Debroux 15A wendy cameron at aise eu No Association for Soaps Detergents Bussels 1160 and Maintenance Products Belgium Argentina Arnaldo J Ministry of Labor Employment Leandro N Alem 650 Piso 2 acaldiro AT trabajo gov ar No Caldirola and Social Security C A B A Argentina Australia Drew Wagner Safe Work Australia 220 Northbourne Avenue drew wagner AT safeworkaustralia gov au No Braddon ACT 2612 Australia EU Uta Jensen Korte European Commission DG European Commission uta jensen korte AT ec europa eu No ENTR and DG ENV DG ENTR Av d Auderghem 45 B 1049 Brussels Belgium EIGA Pierre Wolfs EIGA European Industrial Gases IAvenue des Arts 3 5 p wolfs AT eiga eu No Association B 1210 Bruxelles Canada Kim Headrick Canada consumer chemical 123 Slater St AL 3508 Ottawa Kim Headrick AT hc scg c ca No pesticides and workplace Ontario chemicals Canada SRICI LIU Gang Sh
254. lacking layer Labelling Signal word Hazard pictogram GHSO2 flame GHSOS corrosion GHSOG skull and crossbones GHSOS health hazard Hazard statements Hazard statement Additional text Hazard statement Additional text Hazard statement Additional text Hazard statement Additional text Hazard statement Additional text Hazard statement Additional text Hazard statement Additional text panser Part3 H226 Flammable liquid and vapour H301 Toxic if swellowed H311 Toxic in contact vath skin H314 Causes severe skin burns and eye damage H317 cause an allergic skin reaction H331 Toxic if inhaled H350 May cause cancer lt state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard Precautionary statements Hazard statement Additional text Hazard statement Additional text Hazard statement Additional text Hazard statement Additional text Hazard statement Additional text Hazard statement Additional text Hazard statement Additional text Hazard statement Additional text Hazard statement Additional text Hazard statement Additional text P210 Keep awey from heat sparks open flames f hot surfaces No smoking required for H226 P261 Avoid breathing dust furne gazs rnist vapours spray Avoid breathing vapour P280 Weer protective glowes protective clothing eye protection face protection required for H226 H
255. land http www ermanz govt nz hs compliance chemicals html and through the OECD eChemPortal at http webnet3 oecd org echemportal ECHA inventory list will be available on internet for all users from all countries Norway As Serbian list of classified substances will be fully harmonised with list given in Serbia Annex 6 of EU Regulation 1272 2008 we do not see the need for it See answer to question 1 Switzerland We would like share information and resources of chemicals safely management with SE EAQB UNECE and other countries UN SCEGHS 20 INF 5 Response We could share the list if we have it in future and there are no confidential data Country Organiz SRICI It is already available UN secretariat Not applicable Question 22 If there was an international classification list of chemicals should it be a binding or non binding classification list of chemicals USA Response It should be a non binding list of classifications producers or users should be allowed to self classify if they have data that shows results that are contrary to the listed classification Country Organiz AISE The list must be non binding in the absence of an international convention It should also be non binding when national or regional governments implement the GHS While national regional or even globally available lists or databases of classifications for individual chemicals can provide a useful
256. lasses and categories in order to allow for self classification as far as possible It would be a major change in mid course GHS implementation to change this fundamental GHS principle IPIECA Views vary some prefer that it be binding as e g in the EU Annex VI to Regulation 1272 2008 others prefer non binding for guidance only The consensus harmonisation process mentioned in Question 20 would be a pre requisite to introducing a binding list However all respondents agreed that there should be clearly defined processes for exceptions or to challenge the existing classification if a country or organisation has IPPIC 33 UN SCEGHS 20 INF 5 34 Response Country Organiz data casting doubt on the validity or applicability of a classification in the list It depends on the state s law so far Japan International binding like TDG would be the best It is a problem that should be decided by each country but binding may be better like Korea UN RTDG It is probable that it would have to be non binding in itself It would only become New Zealand binding if adopted into relevant national legislation or international agreements conventions It could be used in a similar way to the current Dangerous Goods list in the UNRTDG Model Regulations See comments above Note refer to question 17 Norway As we suggest using of harmonisation of classification and labelling of substances and Serbia
257. ld prefer to use this on further development of the criteria in the recommendation and a future development of a manual of decision Also resources could be spent on helping developing countries implementing GHS Norway Yes Serbia Yes an international list of harmonized classifications of chemicals would be useful and could be an important part of the overall harmonization process Switzerland 25 UN SCEGHS 20 INF 5 26 Response Country Organiz Very useful SE EAQB Yes there are some lists very useful such as EU list SRICI Yes UN secretariat This question is premature for United States OSHA is currently compiling comments from their stakeholders on the usefulness of lists submitted to OSHA through their rulemaking process OSHA is scheduled to report on the feedback at the next UN subcommittee working group meeting Question 18 What do you see as the primary group of users of an international classification list manufacturer s guidance or for harmonisation only USA Response Any international classification list of GHS classifications for substances should be provided as guidance only Chemical producers or users should be allowed to self classify as far as possible 1n line with GHS 1 3 2 1 2 Companies with valid data that show results which are contrary to the listed classification should be free to use such results for classification Country Organiz AISE Nat
258. ly on the existing EU classifications that are now contained in table 3 2 of the EC CLP Regulation New Zealand See comments above Norway Serbia is in process of harmonisation of national legislation with EU legislation so list given in Annex 6 of EU Regulation 1272 2008 is most convenient for Serbia regarding this question Moreover the EU classification and labelling inventory could be considered in this regards Serbia Several countries regional organisations have already made available their lists e g via OECD eChemPortal Whether or not classifications of a country region are made applicable by other countries will among other factors depent on the transparency of the decision making process and the underlying data sets Switzerland Yes But it may be difficult SE EAQB No it is better to consider the classification lists from more countries industries SRICI 31 UN SCEGHS 20 INF 5 32 Response Several countries intergovernmental bodies have already made available their own list of classification e g European Union New Zealand Japan Country Organiz UN secretariat This may be difficult 1 the underlying data may not be available and 2 there would also need to be a feedback loop for conflict resolution Question 21 Would you be willing to share your list with the UNSCEGHS USA Response Country Organiz
259. ly to be developed as described above Note refer to question 14 As New Zealand resources permit it may be expanded to include some component chemicals which are present only in mixtures in New Zealand Norway will implement the EU regulation on classification and labeling of substances Norway and mixtures CLP See response from the EU commission Yes as it considers the List of classified substances that is transposed from Regulation Serbia 1272 2008 see remark regarding questions 2 16 in the answer to question 1 Switzerland It is likely to be developed as described above in question 14 SE EAQB Yes The list is updated every 2 years but bearing in mind that only substances that are carried in significant quantities are listed the other ones have to be self classified by the industry under the relevant generic entry UN secretariat Nil USA Question 16 Describe how it will be developed Response Country Organiz Not applicable Argentina The same as current arrangements Australia See the answer above about the process of classification EU Not applicable Canada Maintenance or development is at the request of IMO GESAMP is a subsidiary body IMO UN SCEGHS 20 INF 5 Response Country Organiz Ministries concerned fund and organize the classification projects Japan About 1 800 2 000 chemicals will be newly classified every year Korea The chemicals already classifi
260. ment National Emergency Management Agency has the lists ofhazardous chemicals For example there are lists about Toxic Substances in Toxic Chemicals Control Act and dangerous goods in Dangerous goods Safety act Korea No although the list in the UNRTDG Model Regulations is used for the transport of dangerous goods in New Zealand through adoption in the New Zealand Standard NZS 5433 2007 Transport of dangerous goods on land New Zealand Norway will implement the EU regulation on classification and labeling of substances and mixtures CLP See response from the EU commission Norway The list of poisons based on the old Law on Production and Marketing of Poisonous Chemicals which is repealed by new Law on chemicals in May 2009 contains dangerous chemicals not only poisons but classification criteria were not well defined and there for were not comparable with GHS criteria However this list will be replaced by new list of hazardous chemicals classified in terms of the GHS and transposed from Annex 6 of EU Regulation 1272 2008 so the List of poisons is not relevant in terms of GHS and the international classification list Serbia Yes Chinese State Administration Of Work Safety has announced Dangerous chemicals List Rev 2008 SE EAQB China see remark regarding questions 2 16 in the answer to question 1 Switzerland Yes The list has been developed and regularly updated since 1953 under the aus
261. mical administration on the lung adenoma response in strain A J mice Toxicol appl Pharmacol 82 19 31 INCHEM The effects of exposure to epichlorohydrin by inhalation on the fertility of male and female Sprague Dawley rats 30 sex group exposed at nominal concentrations of 0 5 25 or 50 ppm for 6 hrs day 5 days week for 10 weeks and held for a recovery period of 10 weeks were evaluated The male rats were mated with unexposed females and the exposed females were mated with unexposed males There were significant differences observed between treated and control FO animals in the following decreased body weight and weight gain 50 ppm females and males increased white blood counts all exposed rats decreased red blood cell count males at 50 ppm and at interim sacrifice 10th week increased relative and absolute weight of kidney and degenerative change in nasal turbinates both sexes at 50 ppm and 25 and 50 ppm respectively There were significant differences observed in the following exposed male reproductive parameters marked decreased in number of fertile males 50 ppm group all 4 exposure mating periods recovery of fertility was observed as early as 1st recovery mating in 2nd week of recovery decreased number of implantations in unexposed females mated to 25 and 50 ppm males during exposure period decreased number of corpora lutea exposure period all matings at 50 ppm mating at 25 ppm decreased number of resorptions 1st re
262. nces only Australia Substances only as a start If there is agreement on the classification of the substances the classification of the mixtures is less a problem EIGA For practical reasons e g millions of possible mixtures lifetime of a mixture on the market can be expected to be shorter than administrative measures to incorporate them into a list the list should only include substances Currently in the EU alone there are an estimated 50 000 substances on the market and possibly 2 10 million mixtures However extremely well defined and conservative widely used mixtures like the coal and oil derivatives could be included In addition the TDG model whereby N O S entries cover mixtures and solutions that are not explicitly named may be an alternative model to consider if the list were to cover mixtures EU The initial focus should be on substances Canada Chemicals come in all forms many are mixtures GESAMP s list contains real chemicals as they are shipped and not just pure substances which are easier to study IMO Existing classification lists are typically for substances and the GHS already contains criteria for the classification of mixtures The feasibility of including true mixtures cannot be supported due to a number of practical considerations Firstly there is the issue of the extremely large number of mixtures Furthermore the details of mixture composition are often company specifi
263. nd HSNO Act an approval number will be given on the CCID record they are legally binding for that chemical Norway will implement the EU regulation on classification and labeling of substances Norway and mixtures CLP See response from the EU commission Not relevant because of the reasons given previous responses question No 2 and 1 Serbia see remark regarding questions 2 16 in the answer to question 1 Switzerland No SE EAQB The list as it appears in the UN Model Regulations is not legally binding since these Model Regulations are of a recommendatory nature However it has been transposed as a mandatory list into all major international and regional legal instruments regulating the international transport of dangerous goods such as the European Agreement on the Transport of Dangerous Goods ADR 45 contracting parties the International Maritime Dangerous Goods Code IMDG Code mandatory in 159 countries the ICAO Technical Instructions on the Safe Transport of Dangerous Goods by Air mandatory in 190 countries European Agreement on the Transport of Dangerous Goods by inland Waterways ADN 13 Contracting Parties Regulations concerning the International Carriage of Dangerous Goods by Rail 44 countries It has UN secretariat 11 UN SCEGHS 20 INF 5 12 Response also been transposed as a mandatory list into national legislation governing inland domestic traffic in many countries of the wo
264. ne Notified classification and labelling according to CLP criteria Flam Liq 3 H226 H226 Acute Tox 3 H301 H301 Acute Tox 3 H311 H311 GHS06 1 GHS02 Skin Corr 1B H314 H314 GHS05 666 GHS08 Skin Sens 1 H317 H317 Dgr Acute Tox 3 H331 H331 Carc 1B H350 H350 Flam Liq 3 H226 H226 Acute Tox 3 H301 H301 Acute Tox 3 H311 H311 GHS02 GHS06 Skin Corr 1B H314 H314 GHS05 117 GHS08 Skin Sens 1 H317 H317 Dgr Acute Tox 3 H331 H331 1 H350 H350 Flam Liq 3 Acute Tox 3 Acute Tox 3 Skin Corr 1B Skin Sens 1 Eye Dam 1 Acute Tox 3 Carc 1B Repr 2 Flam Liq 3 Acute Tox 3 Acute Tox 3 Skin Corr 1B Skin Sens 1 Acute Tox 3 Carc 1B Repr 2 Flam Liq 3 Acute Tox 3 Acute Tox 3 Skin Corr 1B Skin Sens 1 Acute Tox 3 Carc 1B H226 H301 H311 H314 H317 H318 H331 H350 H361 H226 H301 H311 H314 H317 H331 H350 H361 H226 H301 H311 H314 H317 H331 H350 H226 H301 H311 H314 H317 H318 H331 H350 H361 H318 H226 H301 H311 H314 H317 H331 H226 H301 H311 H314 H317 H331 H350 GHS02 GHS06 GHS05 GHS08 Dgr GHS0G GHS02 GHS05 GHS08 Dgr GHS06 GHS02 GHS05 GHS08 Dgr 43 29 22 203 439 8 1 chloro 2 3 epoxypropane 106 89 8 liquid Flam Liq
265. ng such a list should be set aside until the time when countries are more harmonized on the options they adopted for GHS implementation ACI Yes because it will provide the same classification criteria Argentina If the classifications of the chemicals were derived based on an internationally agreed process to which Australia subscribed then yes the list would be useful but only for guidance purposes rather than regulation For an international classification list to be useful particularly as a guide to foster consistency internationally agreed processes would need to be developed for the nomination of candidate chemicals review processes and the classification of chemicals choice of end points study relevance etc as well as for managing data ownership issues Australia would need to engage in whole of government discussions before agreeing how such a list could be developed and used This would need to be further considered as a significant policy decision of government Australia YES Most suppliers of chemicals operate on a global basis and are using global management tools for classification labelling SDS transport documents etc A difference in classification in different regions for the same chemical prevent the effective use of the global tools EIGA To set up an international list of classified substances could be very useful It is also in EU UN SCEGHS 20 INF 5 Response line with
266. ntry EU Commission EU Response compiled by the experts of the European Commission on behalf of the EU member states participating in the GHS Sub Committee NL view ideas on the second part future discussions on classification lists of the UN SCE GHS Survey on Existing Classification Lists of Hazardous Dangerous Chemicals As a first step we propose to establish a world wide public inventory of the GHS classification of substances This inventory should combine at substance level information on the GHS classification based on the following input Industry submissions of GHS classification for substances based on self classification Legally binding GHS classification of substances as included in a list of a Member State or group of Member States Existing inventories databases of GHS classifications of substances e g EU CLP inventory The coordination of such a public inventory should be preferably done by the OECD The final result will be a public database of substances with one or more GHS classifications The world wide public inventory should indicate the origin of the classification e g legally prescribed in Member State X or self classification As a second step parallel activities could be undertaken on the basis of the OECD world wide public inventory a Harmonization of the GHS classification of substances included in the UN dangerous good list for the GHS hazard classes used by transport with coordination of UN T
267. o question 1 Switzerland Government SE EAQB The list is maintained by the UN Secretariat on the basis of the decisions taken by the TDG Sub Committee and inputs by both governments and industry UN secretariat A qualified yes it is time consuming and cumbersome to keep a list of 10s of USA thousands chemicals up to date Question 4 Who owns maintains the classification list of chemicals Response Country Organiz Not applicable Argentina The current non GHS lists are maintained by Safe Work Australia and by the Australia Commonwealth Department of Health and Ageing see above EU Not applicable Canada GESAMP issues a GHS compatible hazard profile not a classification at the request IMO of IMO the owner is IMO and GESAMP Maintained by the ministries concerned Japan UN SCEGHS 20 INF 5 10 Response Country Organiz The list is maintained by KOSHA Korea Maintained by ERMA NZ under the provisions of the Hazardous Substances and New New Zealand Organisms Act HSNO Act Norway will implement the EU regulation on classification and labeling of substances Norway and mixtures CLP See response from the EU commission Not relevant because of the reasons given previous responses question No 2 and 1 Serbia see remark regarding questions 2 16 in the answer to question 1 Switzerland Maintained by Chinese government SE EAQB The TDG Sub Committee UN secretariat
268. o you have sufficient resources for maintaining the list Response Not applicable Country Organiz Argentina There are adequate resources to maintain the existing classification list of chemicals HSIS however this is dependent on the EU continuing to revise their classification list in table 3 2 in Annex 6 ofthe CLP regulations There are limited resources available to maintain the chemicals listed under the Poison Schedules Australia CLP list The legal basis to maintain the list is laid down Title V Chapter 1 of the CLP Regulation Inventory The legal basis to maintain the Inventory is laid down in article 42 of the CLP Regulation EU Not applicable Canada Yes industry submitting new substances for evaluation is charged a fee per hazard profile The work is also supported by IMO since 1969 IMO It depends on the number of chemicals to be classified Japan Yes Korea At present yes Only a few new chemicals are introduced to New Zealand each year and these are able to be added to the list Also corrections are able to be made to the list as new information 1s provided and classifications updated on an annual basis New Zealand Norway will implement the EU regulation on classification and labeling of substances and mixtures CLP See response from the EU commission Norway This question is not relevant for old List of poisons but government established the Ser
269. onstructed at any point in time on the basis of the archived information IMO Concerning the GHS classification Yes Concerning substances regulated in the laws No Japan No but in preparation The data concerning classification can be searched on website by each chemical not the list Korea Yes In many cases this is test data from international published sources that has been evaluated against the HSNO GHS classification criteria In other cases the classification has been derived by translation from existing EU classifications ie R phrases New Zealand Norway will implement the EU regulation on classification and labeling of substances and mixtures CLP See response from the EU commission Norway Not relevant because of the reasons given previous responses question No 2 and 1 Serbia see remark regarding questions 2 16 in the answer to question 1 Switzerland No SE EAQB No The secretariat keeps records of data submitted which are issued in official UN documents for consideration by the TDG Sub Committee A form for submitting such data is included as Figure 1 ofthe United Nations Recommendations on the Transport of Dangerous Goods UN secretariat Nil USA 15 UN SCEGHS 20 INF 5 16 B Area GHS Question 10 What type of GHS classified chemicals if any do you have on that list Response Not applicable Country Organiz Argentina
270. or classification Reason for no Classification inconclusive Reason for no Classification Reason for no Classification conclusive but not sufficient for classification Reason for no Classification conclusive but not sufficient for classification Reason for no Classification conclusive but not sufficient fo Classification Part 3 Hazardous to the aquatic environment acute Hazardous to the aquatic environment chronic Hazardous to the atmospheric environment No available Data Labelling conclusive but not sufficient for classification data lacking conclusive but not sufficient for classification H226 Flammable liquid and vapour H301 Toxic if swallowed H311 Toxic in contact with skin H314 Causes severe skin burns and eye damage H317 May cause an allergic skin reaction H318 Causes serious eye damage H331 Toxic if inhaled H350 May cause cancer e unborn child Suspected of damaging fertility or the No available Data 6 EU ECHA REACH ECHA EUROPEAN CHEMICALS AGENCY Advanced search gt About Us Regulations Addressing Chemicals Information on Chemicals in our Life Support A of Concern Chemicals ECHA gt Information on Chemicals gt Registered substances xnsu 47 About
271. ough general categories and might given the necessary adaptations serve as a foundation on which to build a harmonized list The IARC list could also be as starting point with regards carcinogenicity EU International Programme on Chemical Safety International Chemical Safety Cards Canada Chemicals in trade the Conventions generally look after their own listed chemicals Stockholm s list is short and does not cover many commodity chemicals IMO Developing and maintaining an international classification list of hazardous chemicals will be very resource intensive It will be important to prioritize resources to develop a list that has maximum impact and value for the resources expended A first step would be to review existing national regional classification lists to establish priority setting since those lists already represent priorities for those countries The first step in development of any classification list is the development and agreement on the criteria for inclusion of chemicals on the list It would be logical to start with common hazardous high volume chemicals with multiple suppliers that are in international trade To facilitate acceptance and have a propitious beginning it would also be logical to start with the chemicals where there is already agreement among the existing lists The UN TDG list contains the high volume chemicals most frequently found in commerce However a major issue is that mat
272. pices of the UN ECOSOC Sub Committee of Experts on the Transport of Dangerous Goods TDG Sub Committee on the basis of criteria which were to a large extent especially for physical hazards fully compatible with those of the GHS For health hazards the list also takes account of human experience UN secretariat Yes the United States has several lists of chemicals developed through both government agencies and consensus organizations See below for a partial list of various chemical databases USA UN SCEGHS 20 INF 5 Question 3 Is it a list maintained by a government or an industry Response Country Organiz Not applicable Argentina Government Australia The CLP list is maintained by the European Commission Regularly additional or EU revised classifications are included in Annex VI The last amendment was published in 2009 The Inventory will be established and maintained by the European Chemicals Agency ECHA Not applicable Canada By a UN technical organization namely IMO IMO Maintained by the ministries concerned Japan Yes it is maintained by each ministry Korea Government New Zealand Norway will implement the EU regulation on classification and labeling of substances Norway and mixtures CLP See response from the EU commission Not relevant because of the reasons given previous responses question No 2 and 1 Serbia see remark regarding questions 2 16 in the answer t
273. re also designed to be part of education and training activities UN SCEGHS 20 INF 5 Toxnet http toxnet nlm nih gov A search engine accessing several databases on toxicology hazardous chemicals environmental health and toxic releases provided by the National Library of Medicine ATSDR profiles http www atsdr cdc gov toxpro2 html By Congressional mandate the Agency for Toxic Substances and Disease Registry ATSDR produces toxicological profiles for hazardous substances found at National Priorities List sites These hazardous substances are ranked based on frequency of occurrence at NPL sites toxicity and potential for human exposure Toxicological profiles are developed from a priority list of 275 substances ToxFAQs http www atsdr cdc gov toxfaq html The ATSDR ToxFAQs is a series of summaries about hazardous substances which contain information excerpted from the ATSDR Toxicological Profiles and Public Health Statements Each fact sheet serves as a quick and easy to understand guide Answers are provided to the most frequently asked questions about exposure to hazardous substances found around hazardous waste sites and the effects of exposure on human health Medical Management Guidelines http www atsdr cdc gov MHMI mmg html The Medical Management Guidelines MMGs for Acute Chemical Exposures were developed by ATSDR to aid emergency department physicians and other emergency healthcare professionals who m
274. reference for classifiers and labelers particularly those with fewer resources e g small enterprises use of such lists should be voluntary under all circumstances Chemical producers or users should be allowed to self classify which is consistent with paragraph 1 3 2 1 2 of the GHS ACI Non binding but with the option of each country to make it binding in their legislation Argentina Since the GHS relies on self classification by industry if agreed a list should be non binding because manufacturers and suppliers have a duty to classify chemicals under workplace laws The decision on whether any such list should be binding is in any case not a matter for the UNSCEGHS and would need to be a decision of each country Australia Yes It should be binding as a minimum classification that industry could override if they have evidence of data for more stringent classification EIGA Non binding but with the option for countries or regions to make it binding in their legislation EU The question is premature until the questions of classification criteria and datasets are answered Canada Making lists binding under existing chemicals conventions seems unrealistic IMO A basic premise of the GHS is self classification According to the following statement in the GHS Purple Book Section 1 3 2 1 2 One objective of the GHS is for it to be simple and transparent with a clear distinction between c
275. rises of the transport sector professional users of chemicals NGOs authorities of countries Switzerland This international classification list can help classification harmonization between different countries and give guides to manufacturers retailers transport departments and customers SE EAQB The list should be consistent in all countries no matter it is used for guidance or for harmonisation SRICI Manufacturers especially small and medium enterprises control and enforcement authorities developing countries UN secretariat We will include this in our feedback in July USA 27 UN SCEGHS 20 INF 5 28 Question 19 Who should develop and maintain such an international list Response Suggest that such a list should come under the auspices of the UNSCEGHS Country Organiz AISE If a program to develop an international list were to go forward the capabilities of candidate intergovernmental organizations to develop and manage the list should be assessed against a set of criteria The criteria should address the size of the resources and competency of the resources needed to perform the task Regarding the needed competency the development of an international list would require strong expertise in environmental and human health assessment such as OECD and IPCS During the development of procedures for creating an international list of classifications the implementation of those proc
276. rld e g but not limited to all EU countries USA Canada Australia Country Organiz If we understand this question the only chemical database that is GHS compliant is the one used by U S DOT and this database is binding for the shipping and transport sector Question 7 By which process is the classification of chemicals derived USA Response Not applicable Country Organiz Argentina The substances on HSIS are classified in accordance with the Australian Approved Criteria for Classification of hazardous substances which is based on the pre GHS EU classification scheme The substances on Australia s Poisons Schedule are classified in accordance with Australian specific guidelines that include both hazard and risk assessment processes to categorise chemicals Australia CLP list In accordance with Article 37 of the CLP Regulation proposals for harmonised classifications can be submitted by EU Member States MS Competent Authorities CAs or subject to certain conditions by industry These proposals are to be submitted to ECHA established under Regulation EC No 1907 2006 REACH Regulation After the consultation of the Risk Assessment Committee RAC managed by ECHA and composed of experts from EU MS and stakeholders ECHA prepares a harmonised classification and labelling proposal The proposal is then open for public consultation Following the public consultation RAC prepares an opinion on the p
277. roposal for harmonised classification and labelling and ECHA forwards the opinion and comments received to the EU Commission The Commission if it finds the harmonisation of the classification and labelling of the substance concerned appropriate will draft a legislative proposal to include the classification and labelling information in the Tables 3 1 and until 01 June 2015 in Table 3 2 of Annex VI to the CLP Regulation The legislative proposal will need to be adopted by a regulatory procedure with scrutiny Inventory Where for the same substance the notifications result in different entries on the Inventory the notifiers shall make every effort to come to an agreed entry to be included in the inventory The notifiers shall inform ECHA accordingly EU Not applicable Canada Hazard profiles are determined by peer review of publicly available and proprietary industry data IMO UN SCEGHS 20 INF 5 Response The GHS inter ministerial committee has discussed the classification result when the substance is classified according to the GHS Currently there is another mechanism to classify the substances which are regulated in the laws described above Country Organiz Japan Chemicals are classified by expert judgement according to internal classification guideline Korea Existing chemicals pre 2001 were transferred into the HSNO Act framework by ERMA NZ following classification against the criteria
278. the classification and labelling inventory given in Title V of EU Regulation 1272 2008 as model for development of this list this list should not be legally binding at first step but after the harmonisation 1s achieved maybe it could be binding in second step A non binding list Option to incorporate it in the Purple Book Annex and make it Switzerland available for the Building Block Approach Non binding but with the option of each country to make it binding in their SE EAQB legislation It should be binding so that better for pushing the harmonisation process SRICI A binding list could exist only under a binding legal instrument Developing a binding instrument a convention would raise the question of making the GHS itself of a binding nature and so far this approach has not been supported by governments involved in the development of the GHS This could also cause problems of inconsistencies with existing lists which are of mandatory application under legal instruments and therefore some complications in international law The same approach currently being used with the Dangerous Goods List could be applied to the GHS i e the recommended classification in the GHS would only become legally binding once transposed into the relevant national regional international legislation The current system applied for transport of dangerous goods is rather flexible it allows any interested government organization to provide input feedback
279. tion Cl gical information Guidance on safe use Type of substance Composition mono constituent substance Origin organic Trade names 2 Chloromethyljoxirane Epichlorohydrin official classification General Information Not classified Implementation State form of the substance Remarks Related composition Classification Physical hazards Exposives Flammable gases Flammable aerosols Oxidizing gases Gases under pressure Flammable liquids Flammable solids Self reactive substances and mixtures Pyrophoric liquids Pyrophoric solids Self heating substances and mixtures Substances and mixtures which in contact with water emits flammable Oxidising liquids Oxidising liquids Oxidising solids Organic peroxides Corrosive to metals EU liquid This classification is taken from Table 3 1 of REGULATION EC No 1272 2008 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL of 16 December 2008 on classification labelling and packaging of substances and mixtures amending and repealing Directives 67 548 EEC and 1999 45 EC and amending Regulation EC No 1907 2006 Index No 603 026 00 6 The database for this classification is not available therefore conclusive but not sufficient for classification is used for no classification in all fields where no classification is necessary according to EC 1272 2008 Epichlorohydrin data lacking data lacking data lacking data lacking data lacking Flarn Liquid
280. tion test results grouped by chemical class Drug Chem Toxicol 4 331 51 IUCLID 2000 Auditors comments Balance on current data human CA and 6 7 classification direct bifunctional alkylating agent Therefore 6 6A classification Overall evaluation Epichlorohydrin is probably carcinogenic to humans Group 24 A Evidence for carcinogenicity to humans inadequate Cohort studies of 474 and 389 workers exposed in 1948 1965 and 1955 1965 to epichlorohydrin in two factories in Texas and Louisiana USA respectively showed slight excesses of lung cancer In one ofthe factories six cases 14 were observed with 4 2 expected four of these workers had also been engaged in the manufacture of isopropyl alcohol In the other four cases were 6 8B observed 3 1 expected None ofthese excesses was statistically significant even after pooling the data on lung cancer ref 1 Another cohort study of 606 workers exposed to epichlorohydrin and other chemicals in four European factories was inconclusive due to small cohort size and short follow up The expected number of all cancers was 5 0 four cases were found ref 2 B Evidence for carcinogenicity to animals sufficient Epichlorohydrin was tested in rats by oral administration inducing papillomas and carcinomas ofthe forestomach ref 3 4 and by inhalation inducing papillomas and carcinomas of the nasal cavity ref 5 Itwas also tested in mice by skin application and by subcutaneous an
281. to substances listed under international treaties such as the Rotterdam or Stockholm Conventions since it would be expected that these substances would be well characterized and already have a defined dataset as a result of the deliberations that led to their being listed ACI A starting point could be the substances produced and commercialized internationally in great quantities Argentina Countries could nominate priority chemicals following an agreed process perhaps similar to that of the Stockholm Convention or Rotterdam Convention The focus should be on commonly traded chemicals and ones where existing classifications are available such as the UN dangerous goods list Australia UN SCEGHS 20 INF 5 Response Country Organiz UN List of chemicals Dangerous Goods List EIGA Depending on the list to start with it could be an ongoing process which self prioritises the substances to come and the hazard categories to cover A first option could be that the initial priority should focus on widely traded produced chemicals for which there is already a range of data available As a starting point the chemicals from the Rotterdam or Stockholm Conventions or from the OECD HPV chemicals program for which there is substantial industry generated data should be considered Another option is the UN dangerous goods list for transport that has the advantage of encompassing all possible chemicals and mixtures thr
282. zard assessments and or classifications on an international level e g OECD IARC SCE TDG could be involved in the process and contribute to the development of a list Switzerland A kind of system should be built to make this list be maintained regularly like dangerous goods list in UN Model Regulations SE EAQB GHS sub committee and other relative organisations SRICI Organisations intergovernmental and NGOs and governments which have specific expertise in chemical classification should contribute to the exercise but the list should be kept under the control of the GHS Sub Committee and issued by it to make sure that there is consensus on the harmonized classification proposed UN secretariat Initial comments have indicated that the International Chemical Safety Cards may be appropriate since they are peer reviewed They have already begun the process of providing GHS classifications They have completed GHS classifications for approximately 2596 of the chemicals on their list However see the comment below Note refer to question 20 USA 29 UN SCEGHS 20 INF 5 30 Question 20 Would it be possible to make a classification list of one country industry available for all countries Response Believe it could be possible the EU list of substances with harmonised classifications is freely available on the internet and has been used by other countries in the past The EU classifi
283. zard statements H351 hazard statements H360 hazard_statements H370 Dro AES io hazard_statements H372 J hazard_statements H401 4 hazard statements HA11 precautionary_statements k Ze E ti TES t precautionary_statements precautionary statements precautionary_statements f P24 precautionary_statements 4 P240 precautionary_statements lt gt H

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