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1. 2 8 30 302. 10 3 158 pL 108 kL 3
3. 2 8 2 8 2 8 2 8 5 10
4. 12 7 HCV Ag 20 000 fmol L gt 20 000
5. HAMA Human Anti Mouse Antibodies HAMA 2 zo 4 IgM
6. S EU C R S35 S36 37 39 MS EU C R S
7. 1 2 ProClin 1 HIV HBV HCV HBs
8. 30 2
9. E LT 2 8 2 8 2 30C 12 12 18 HCV Ag 6L47 26 100 6 7 mL 1 6 1 mL 1 30 0 mL 1
10. 2 8 20 2 10 C HCV C 500 mg dL i A 20 mg dL 3000 mg dL 92 gdL CLIA C
11. 9 20 20 pL 380 kL ARCHTTECT HCV Ag 3 00 fmol L A F 2 1
12. 0 20 000 fmol L 24 1 3 00 fmol L HCV 3 00 fmol L HCV 3 00 fmol L 6
13. HCV B F Bound B Free F 3 1 2 ARCHITECT TEA HCV HCV HCV HCV HCV HCV HCV
14. a 5
15. 3 1 108 L 32L 1 90 pL 2 50 gL 2 1 200 pL 90gL 50 pL 3 50 kL 4 100 pL 5 300 kL 400 500nm 6 HCV 7 1 5 HCV
16. 4PLC 10 00 fmol L 2 2 3 00 fmol L HCV 3 00 fmol L 3 00 fmol L HCV HCV RNA
17. 6 10 HCV Bicine TRIS RO ER ENE I
18. 2 3
19. EEE HCV on dal de A RR 1 2 8 5 2 5 20C 3
20. 9 C HCV HCV RNA 1 2 NM 3 MA NE 4
21. fmolD M pg mD CALlA 000 000 CALlB 10 00 0 20 cAulc 80 00 160 cALlp 600 00 12 00 CALlE 4 50000 9000 CALF 20 000 00 400 00 ARCHITECT HCV Ag ARCHITECT HCV Ag Controls 6L47 11 8mL 3 HBs HIV 1 HIV 1 RNA HCV HTV 1 HTV 2 ProClin 300 ProClin 950 1 2 HCV EmolL pg mD fmolL pg mL CONTRoL 000 000 000 299 000 005 CONTROL 1 5000 100 3500 6500 0 70 1 30 CONTROL 2 b 300 00 6 00 21000 39000 420 7 80 a Acid Blue No 9 b Red D amp C No 33
22. a Se S36 37 39 m MM EU R S B F 1 2 EU Xi
23. R S KR AO EU Xi R S
24. 161_020 iae fmol L pg mL 0 02
25. 12 L 50 gL 78 pL 7 1 ARCHITECT i CD ROM Addition C HCV Ag 801_002 iae HCV Ag ARCHITECT 5 00 ARCHITECT i CD ROM Addition C 6 0 8K30 06 HCV HCV Ag ARCHITECT HCV Ag 27 0 6E59 27 ARCHITECT i CD ROM HCV
26. 3350 RV 24 1 Ff ARCHITECT HCV Ag B 10 fmol L A 0 fmol L 10 4 4 5 4 F 20 000 fmol L A 0 fmol L 4315 5390 2 7 5 15 1 3 3 CV 2 5 10 6 4 3 00 fmol L 20 000 00 fmol L 180 000 00 fmol L 5 1 2 3 4 IRMA n 177 r 0 94 x IRMA
27. OSHA Standard on Bloodborne Pathogens 25 78
28. HCV HCV HCV HCV 1 2 ARCHITECT i CD ROM Addition C 6 0 ARCHITECT HCV Ag ARCHITECT HCV Ag Calibrators 6L47 02 4 mL 6 A B F HCV
29. 1 14 5 mL 1 2 110mL 1 5 9 mL 1 6E23 975 mL 4 6C55 975 mL 4 1 HCV ARCHITECT HCV Ag 45 4 454 466 2007 2 Primus FJ Kelley EA Hansen HJ et g7 Sandwich Type Immunoassay of Carcinoembryonic Antigen in Patients Receiving Murine Monoclonal Antibodies for Diagnosis and Therapy Clin Chem 1988 34 2 261 4 3 Schroff RW Foon KA Beatty SM et al Human Anti Murine Immunoglobulin Responses in Patients receiving Monoclonal Antibody Therapy Cancer Res 1985 45 879 85 4 Boscato LM Stuart MC Heterophilic Antibodies A Problem for All Immunoassays Clin Chem 1988 34 1 27 33 5 US Department of Labor Occupational Safety and Health Administration 29 CFR Part 1910 1030 Bloodborne pathogens 6 US Department of Health and Human Services Biosafety in Microbiological and Biomedical Laboratories 5th ed Wash
30. 2 8C 15 30 3 HIV HBV HCV 1 000 ppm 1 2 1 121 C 20 0 1
31. 2011 CE Abbott
32. F5 0206 1 R6 IO 2011 2 4 2010 10 3 a a 200600 1643000 EDTA C EDTA CPD HCV Ag
33. ington DC US Government Printing Office January 2007 7 World Health Organization Laboratory Biosafety Manual 3rd ed Geneva World Health Organization 2004 8 Clinical and Laboratory Standards Institute Protection of Laboratory Workers from Occupationally Acquired Infections Approved Guideline Third Edition CLSI Document M29 A3 Wayne PA Clinical and Laboratory Standards Institute 2005 HCV Chiron Corporation HCV Ag Ortho Diagnostic Systems and Chiron Corporation 270 2214 278 TEL 0120 031441 e 3 Oo 270 2214 278 TEL 047 385 2211 ABBOTTJAPAN CO LTD
34. y ii n 117 r 0 95 y 0 67x 1 59 x IRMA y CLEIA n 67 r 0 97 y 0 70x 117 76 cx CLEIA y hi n 119 r 0 96 y 0 61x 2 07 cx CLEIA y HCV RNA 46 n 211 r 0 90 y 1 66x x HCV RNA y HCV HCV HCV A235nm mol y 0 70x 45 12
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